Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NB110-1948 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-1948, RRID:AB_789418
- Product name
- Rabbit Polyclonal COX-2 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. The does not cross react with Cox-1.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antigen sequence
carboxy-terminus of human Cox-2.
- Vial size
- 0.05 ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references The Effect of Biotinylated PAMAM G3 Dendrimers Conjugated with COX-2 Inhibitor (celecoxib) and PPARγ Agonist (Fmoc-L-Leucine) on Human Normal Fibroblasts, Immortalized Keratinocytes and Glioma Cells in Vitro.
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.
Induction of NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase expression by androgens in human prostate cancer cells.
Uram Ł, Misiorek M, Pichla M, Filipowicz-Rachwał A, Markowicz J, Wołowiec S, Wałajtys-Rode E
Molecules (Basel, Switzerland) 2019 Oct 22;24(20)
Molecules (Basel, Switzerland) 2019 Oct 22;24(20)
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice.
Khan OM, Akula MK, Skålen K, Karlsson C, Ståhlman M, Young SG, Borén J, Bergo MO
Circulation 2013 Feb 19;127(7):782-90
Circulation 2013 Feb 19;127(7):782-90
Induction of NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase expression by androgens in human prostate cancer cells.
Tong M, Tai HH
Biochemical and biophysical research communications 2000 Sep 16;276(1):77-81
Biochemical and biophysical research communications 2000 Sep 16;276(1):77-81
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: COX-2 Antibody [NB110-1948] - Detection Cox-2 present in Cox-2 transfected Sf9 cell extract (lane 1) and IL-1Beta induced WISH cell extract (lane 2). Detection occurs using a 1:10,000 dilution of antibody followed by 1:10,000 dilution of HRP Goat-a-Rabbit with visualization via ECL. Film exposure approximately 1’.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: COX-2 Antibody [NB110-1948] - Immunohistochemistry. CDK5 antibody was diluted 1:500 to detect CDK5 in human brain cortex tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: COX-2 Antibody [NB110-1948] - Anti-CUL4 antibody was diluted 1:500 to detect CUL4 in human testes tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counter stain.