Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 10-7543-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-Arginase-1 Antibody
- Antibody type
- Monoclonal
- Description
- Arginase-1 (Arg-1) is a binuclear manganese metalloenzyme that catalyzes the hydrolysis of arginine to ornithine and urea. It is expressed in normal human liver with a high degree of specificity, concentrated in periportal hepatocytes. Arginase-1 are urea cycle enzymes used to distinguish hepatocellular carcinoma from other carcinomas. Two transcript variants encoding different isoforms have been found for this gene. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant Argina
se-1 protein (amino acids 11-230) w
as used as the immunogen for this a
ntibody- Isotype
- IgG
- Antibody clone number
- ABM4B35
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of Arginase-1. Anti- Arginase-1 antibody (Clone: ABM4B35) was tested at 2 µg/ml on human liver lysate.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Arginase-1 in human liver tissue using Arginase-1 antibody (Clone: ABM4B35) at 15 µg/ml.
- Protocol
- Protocol
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Arginase-1 in human liver tissue using Arginase-1 antibody (Clone: ABM4B35) at 5 µg/ml.
- Protocol
- Protocol