HPA003595

antibody from Atlas Antibodies

Targeting: ARG1

Provider product page for HPA003595

Western blot

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [17]
Comments [0]
Validations
Immunohistochemistry [1]

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Product number: HPA003595 - Provider product page
Provider: Atlas Antibodies
Proper citation: Atlas Antibodies Cat#HPA003595, RRID:AB_1078190
Product name: Anti-ARG1
Antibody type: Polyclonal
Description: Polyclonal Antibody against Human ARG1, Gene description: arginase 1, Validated applications: IHC, WB, Uniprot ID: P05089, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µl
Concentration: 0.2 mg/ml
Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Handling: The antibody solution should be gently mixed before use.

ARG1 protein structure - HPA003595 shown in red.

Submitted references Liraglutide Therapy in Obese Patients Alters Macrophage Phenotype and Decreases Their Tumor Necrosis Factor Alpha Release and Oxidative Stress Markers—A Pilot Study

Bułdak Ł, Bołdys A, Skudrzyk E, Machnik G, Okopień B
Metabolites 2024;14(10):554

Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion

Bishop E, Dimitrova M, Froggatt A, Estevez-Cebrero M, Storer L, Mussai F, Paine S, Grundy R, Dandapani M, Prodam F
BioMed Research International 2022;2022(1)

A Novel NIPBL-NACC1 Gene Fusion Is Characteristic of the Cholangioblastic Variant of Intrahepatic Cholangiocarcinoma

Argani P, Palsgrove D, Anders R, Smith S, Saoud C, Kwon R, Voltaggio L, Assarzadegan N, Oshima K, Rooper L, Matoso A, Zhang L, Cantarel B, Gagan J, Antonescu C
American Journal of Surgical Pathology 2021;45(11):1550-1560

Evaluation of Glycosylated PTGS2 in Colorectal Cancer for NSAIDS-Based Adjuvant Therapy

Venè R, Costa D, Augugliaro R, Carlone S, Scabini S, Casoni Pattacini G, Boggio M, Zupo S, Grillo F, Mastracci L, Pitto F, Minghelli S, Ferrari N, Tosetti F, Romairone E, Mingari M, Poggi A, Benelli R
Cells 2020;9(3):683

LmjF.22.0810 from Leishmania major Modulates the Th2-Type Immune Response and Is Involved in Leishmaniasis Outcome

Vacas A, Fernández-Rubio C, Larrea E, Peña-Guerrero J, Nguewa P
Biomedicines 2020;8(11):452

Transient Support from Fibroblasts is Sufficient to Drive Functional Vascularization in Engineered Tissues

Song H, Lammers A, Sundaram S, Rubio L, Chen A, Li L, Eyckmans J, Bhatia S, Chen C
Advanced Functional Materials 2020;30(48)

M2-Polarized Macrophages Determine Human Cutaneous Lesions in Lacaziosis

Barboza T, Sotto M, Kanashiro-Galo L, de Brito A, Duarte M, Quaresma J, Pagliari C
Mycopathologia 2020;185(3):477-483

High-density neutrophils in MGUS and multiple myeloma are dysfunctional and immune-suppressive due to increased STAT3 downstream signaling

Romano A, Parrinello N, Simeon V, Puglisi F, La Cava P, Bellofiore C, Giallongo C, Camiolo G, D’Auria F, Grieco V, Larocca F, Barbato A, Cambria D, La Spina E, Tibullo D, Palumbo G, Conticello C, Musto P, Di Raimondo F
Scientific Reports 2020;10(1)

Alpha-Fetoprotein-Producing Early Gastric Cancer with Intramucosal Hepatoid and Fetal Enteric Differentiation.

Iwaya M, Riddell R, Asano K, Kobayashi K, Uehara T, Ota H
Case reports in gastroenterology 2020 May-Aug;14(2):426-435

Plasticity of High-Density Neutrophils in Multiple Myeloma is Associated with Increased Autophagy Via STAT3

Puglisi F, Parrinello N, Giallongo C, Cambria D, Camiolo G, Bellofiore C, Conticello C, Del Fabro V, Leotta V, Markovic U, Sapienza G, Barbato A, Scalese S, Tibullo D, Brundo M, Palumbo G, Di Raimondo F, Romano A
International Journal of Molecular Sciences 2019;20(14):3548

The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma

Romano A, Parrinello N, Vetro C, Tibullo D, Giallongo C, La Cava P, Chiarenza A, Motta G, Caruso A, Villari L, Tripodo C, Cosentino S, Ippolito M, Consoli U, Gallamini A, Pileri S, Di Raimondo F
Oncotarget 2016;7(41):67333-67346

Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity

Yang J, Gonon A, Sjöquist P, Lundberg J, Pernow J
Proceedings of the National Academy of Sciences 2013;110(37):15049-15054

Local Arginase Inhibition during Early Reperfusion Mediates Cardioprotection via Increased Nitric Oxide Production

Gallyas F, Gonon A, Jung C, Katz A, Westerblad H, Shemyakin A, Sjöquist P, Lundberg J, Pernow J
PLoS ONE 2012;7(7):e42038

Arginase Inhibition Improves Endothelial Function in Patients With Coronary Artery Disease and Type 2 Diabetes Mellitus

Shemyakin A, Kövamees O, Rafnsson A, Böhm F, Svenarud P, Settergren M, Jung C, Pernow J
Circulation 2012;126(25):2943-2950

Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats

Grönros J, Jung C, Lundberg J, Cerrato R, Östenson C, Pernow J
American Journal of Physiology-Heart and Circulatory Physiology 2011;300(4):H1174-H1181

Arginase-1

Yan B, Gong C, Song J, Krausz T, Tretiakova M, Hyjek E, Al-Ahmadie H, Alves V, Xiao S, Anders R, Hart J
American Journal of Surgical Pathology 2010;34(8):1147-1154

A Quantitative Proteomic Approach for Identification of Potential Biomarkers in Hepatocellular Carcinoma

Chaerkady R, Harsha H, Nalli A, Gucek M, Vivekanandan P, Akhtar J, Cole R, Simmers J, Schulick R, Singh S, Torbenson M, Pandey A, Thuluvath P
Journal of Proteome Research 2008;7(10):4289-4298

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Supportive validation

Submitted by: Atlas Antibodies (provider)
Enhanced method: Orthogonal validation
Main image
Experimental details: Immunohistochemistry analysis in human liver and kidney tissues using HPA003595 antibody. Corresponding ARG1 RNA-seq data are presented for the same tissues.
Sample type: Human
Protocol: Protocol
Orthogonal method: Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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