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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 17003-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17003-1-AP, RRID:AB_2156497
- Product name
- ODC1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ODC1 antibody (Cat. #17003-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Pirin Promotes the Progression of Non-Small-Cell Lung Cancer by Increasing ODC1 to Suppress Autophagy.
Putrescine promotes MMP9-induced angiogenesis in skeletal muscle through hydrogen peroxide/METTL3 pathway.
The upregulation of peripheral blood polyamine metabolites spermidine and spermine in children with hand, foot, mouth disease is related to enterovirus 71 capsid protein VP1, but not VP4.
Inhibition of Polyamine Catabolism Reduces Cellular Senescence.
The regulation of polyamine pathway proteins in models of skeletal muscle hypertrophy and atrophy: a potential role for mTORC1.
Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets.
Polyamine pathway activity promotes cysteine essentiality in cancer cells.
Exogenous spermidine ameliorates tubular necrosis during cisplatin nephrotoxicity.
Spermidine rescues proximal tubular cells from oxidative stress and necrosis after ischemic acute kidney injury.
Ornithine is a key mediator in hyperphosphatemia-mediated human umbilical vein endothelial cell apoptosis: Insights gained from metabolomics.
Li YP, Huang ZJ, He QK, Li YX, Zhao XP, Ma ZQ, Qin MJ, Chen AW, Wei Q, Wang Y, Lu CH
Journal of proteome research 2024 May 3;23(5):1713-1724
Journal of proteome research 2024 May 3;23(5):1713-1724
Putrescine promotes MMP9-induced angiogenesis in skeletal muscle through hydrogen peroxide/METTL3 pathway.
Hu C, Ji F, Lv R, Zhou H, Hou G, Xu T
Free radical biology & medicine 2024 Feb 20;212:433-447
Free radical biology & medicine 2024 Feb 20;212:433-447
The upregulation of peripheral blood polyamine metabolites spermidine and spermine in children with hand, foot, mouth disease is related to enterovirus 71 capsid protein VP1, but not VP4.
Li C, Zhang W, Chang X, Di X, Xie Q, Lin B, Zhang H, Ye Z, Lan M, Lian J, Zhang H, Qiu X, Zeng J, Huang M
Translational pediatrics 2023 Feb 28;12(2):194-207
Translational pediatrics 2023 Feb 28;12(2):194-207
Inhibition of Polyamine Catabolism Reduces Cellular Senescence.
Uemura T, Matsunaga M, Yokota Y, Takao K, Furuchi T
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
The regulation of polyamine pathway proteins in models of skeletal muscle hypertrophy and atrophy: a potential role for mTORC1.
Tabbaa M, Ruz Gomez T, Campelj DG, Gregorevic P, Hayes A, Goodman CA
American journal of physiology. Cell physiology 2021 Jun 1;320(6):C987-C999
American journal of physiology. Cell physiology 2021 Jun 1;320(6):C987-C999
Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets.
Sekiguchi M, Seki M, Kawai T, Yoshida K, Yoshida M, Isobe T, Hoshino N, Shirai R, Tanaka M, Souzaki R, Watanabe K, Arakawa Y, Nannya Y, Suzuki H, Fujii Y, Kataoka K, Shiraishi Y, Chiba K, Tanaka H, Shimamura T, Sato Y, Sato-Otsubo A, Kimura S, Kubota Y, Hiwatari M, Koh K, Hayashi Y, Kanamori Y, Kasahara M, Kohashi K, Kato M, Yoshioka T, Matsumoto K, Oka A, Taguchi T, Sanada M, Tanaka Y, Miyano S, Hata K, Ogawa S, Takita J
NPJ precision oncology 2020;4:20
NPJ precision oncology 2020;4:20
Polyamine pathway activity promotes cysteine essentiality in cancer cells.
Zhang T, Bauer C, Newman AC, Uribe AH, Athineos D, Blyth K, Maddocks ODK
Nature metabolism 2020 Oct;2(10):1062-1076
Nature metabolism 2020 Oct;2(10):1062-1076
Exogenous spermidine ameliorates tubular necrosis during cisplatin nephrotoxicity.
Yoon SP, Kim J
Anatomy & cell biology 2018 Sep;51(3):189-199
Anatomy & cell biology 2018 Sep;51(3):189-199
Spermidine rescues proximal tubular cells from oxidative stress and necrosis after ischemic acute kidney injury.
Kim J
Archives of pharmacal research 2017 Oct;40(10):1197-1208
Archives of pharmacal research 2017 Oct;40(10):1197-1208
Ornithine is a key mediator in hyperphosphatemia-mediated human umbilical vein endothelial cell apoptosis: Insights gained from metabolomics.
Zhou R, Kang X, Tang B, Mohan C, Wu T, Peng A, Liu JY
Life sciences 2016 Feb 1;146:73-80
Life sciences 2016 Feb 1;146:73-80
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse thymus tissue were subjected to SDS PAGE followed by western blot with 17003-1-AP( ODC1 Antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ODC1 antibody 17003-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate hyperplasia using 17003-1-AP(ODC1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate hyperplasia using 17003-1-AP(ODC1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
