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- Product number
- 13409-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13409-1-AP, RRID:AB_2156308
- Product name
- OCLN
- Antibody type
- Polyclonal
- Antigen
- Recombinant Protein
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
- Concentration
- 40 mg/ml
- Storage
- -20
Submitted references Targeting Myeloid FoxO1 Ameliorates Sepsis-induced Intestinal Injury by Modulating Tim4(+) Macrophage Glycolysis.
Ulinastatin attenuates capillary leakage and suppresses FoxO1-dependent angiopoietin-2 in sepsis-associated acute lung injury via PI3K pathway.
miR-329-3p derived from mast cells-exosomes exacerbates intestinal ischemia-reperfusion injury by targeting ATG10 to regulate autophagy.
Faecalibacterium prausnitzii: A microbial ally against preeclampsia via extracellular vesicle-mediated ferroptosis inhibition.
Chaihu-Shugan San ameliorates perimenopausal obesity with depression by coordinately targeting hepatic PGC-1α/CYP8B1/PPARγ signaling and gut barrier integrity.
Geometrically Constrained Growth Factor Concentration Favors Enrichment of Goblet Cells and Mucus Formation.
Nitric Oxide Donor Alleviates Cardiac Arrest Induced Blood Brain Barrier Injury by Inhibiting HMGB1-ATG5 Mediated Endothelial Autophagy.
ALKBH5 facilitates Srgn stability via m6A demethylation to disrupt blood-testis barrier integrity in the high-fat diet mice.
Tumor-Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis.
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
Senkyunolide I attenuates radiation-induced cognitive dysfunction by restoring PINK1-Parkin-mediated mitophagy and redox homeostasis.
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
Effects of Modified Xuanbai Chengqi Decoction against secondary Streptococcus pneumoniae infection following influenza virus infection: A multi-omics analysis.
Combined metabolomics and gut microbiota analysis reveals the protective effects of α-monoglucosyl rutin against cyclophosphamide-induced intestinal injury.
Lycium barbarum polysaccharide LBP3 alleviates 5-Fluorouracil-induced intestinal injury via a mechanism associated with activating Nrf2 and improving mitochondrial function.
Differentiating Damp-Heat and Cold-Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short-Chain Fatty Acid Profiling.
Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing.
A microbiota-IPA axis facilitates intestinal stem cell-mediated regeneration in colitis through a Hopx-associated program.
CD177(+) neutrophils alleviate acute pancreatitis-associated lung injury by protecting colonic barrier and restoring gut microbiota.
Development and characterization of immortalized mouse intestinal epithelial cell lines.
Jiawei Danxuan Koukang and Its Component Kaempferol Alleviate Oral Submucous Fibrosis by Restoring Epithelial-Fibroblast Homeostasis and Suppressing Neutrophil Recruitment via the ANXA1/FPR2 Axis.
Puerarin Alleviates Depression via Integrated Regulation of TLR4/MyD88/NF-κB Signaling and Gut Microbiota-Metabolic Axis.
Polydisperse polystyrene microplastics exacerbate colitis through gut microbiota-butyrate-PPARγ axis disruption in mice.
Canine-derived Weissella confusa ZJUIDS-D034 and Enterococcus faecalis ZJUIDS-D016 combat aging by regulating gut microbiota.
The role of the gut microbiota and the nicotinate/nicotinamide pathway in rotenone-induced neurotoxicity.
A Hepatic Oxidative Metabolite of Palmatine Ameliorates DSS-Induced Ulcerative Colitis by Regulating Macrophage Polarization Through AMPK/NF-κB Pathway.
Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway.
Fingolimod Suppresses NLRP3 Inflammasome Activation and Alleviates Oxidative Stress in Traumatic Brain Injury-Induced Acute Lung Injury.
Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin.
Aqueous extracts of Elsholtzia ciliata and Hovenia dulcis ameliorate loperamide-induced constipation in mice by promoting intestinal peristalsis and barrier function and the abundance of intestinal beneficial bacteria.
Porphyromonas gingivalis-induced periodontitis promotes neuroinflammation and neuronal loss associated with dysfunction of the brain barrier.
Association between AHR in EGCs and IBS-D patients: the indole pathway of tryptophan metabolism.
Stachyose alleviates high-fat diet-induced obesity via browning of white adipose tissue and modulation of gut microbiota.
Sulfation and carboxymethylation of Citrus medica 'Fingered' polysaccharides: Physicochemical properties and protective effects against LPS-induced intestinal barrier injury in Caco-2 cells.
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD.
Lycopene ameliorates Di-(2-ethylhexyl) phthalate-induced neurotoxicity in mice via the gut-brain axis.
HDAC/NF-κB signaling pathway mediates gut microbiota dysbiosis in rheumatoid arthritis: Intervention mechanisms of Fengshining decoction.
Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia-Reperfusion Injury.
Lithocholic acid ameliorates ulcerative colitis via the PXR/TLR4/NF-κB/NLRP3 signaling pathway and gut microbiota modulation.
Palmatine ameliorates intestinal epithelial barrier injury in ulcerative colitis via targeting enolase 3.
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/NF-κB/MLCK/MLC signaling in ulcerative colitis.
Electroacupuncture suppresses motor impairments via microbiota-metabolized LPS/NLRP3 signaling in 6-OHDA induced Parkinson's disease rats.
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression.
Neuronal pentraxin 1 accelerates post-stroke atherosclerosis by inducing endothelial cell senescence.
OSBPL2 deficiency impaired cochlear blood-labyrinth barrier via activation of NF-κB signaling pathway.
Basic Fibroblast Growth Factor-Releasing Bioabsorbable Polyglycolic Acid Dura Mater Enhances Neural Progenitor Cell Proliferation and Neuroprotection After Brain Injury.
Traditional wisdom meets modern science: The protective role of sanhuang shu'ai decoction in ulcerative colitis models.
Xinqingning tablet attenuates ischemic stroke complicated by gut dysbiosis through regulating the miR-126-driven gut-brain axis.
Aglycin ameliorates nonalcoholic fatty liver disease through modulation of the gut microbiota, restoration of the intestinal barrier, and inhibition of hepatic inflammation in mice.
Effects of fasudil against photothrombotic stroke in genetically modified obese (ob/ob) mice.
Gut Microbiota and Bile Acid Metabolism in the Mechanism of Ginsenoside Re Against Nonalcoholic Fatty Liver Disease.
Protective effects of jiawei yupingfeng polysaccharides on cyclophosphamide-induced intestinal injury in mice.
Larimichthys crocea isinglass polysaccharide attenuates DSS-induced colitis via gut microbiota regulation and NF-κB signaling inhibition.
Proline rich-39 (PR-39) antimicrobial protein alleviated lipopolysaccharide-induced intestinal barrier dysfunction in piglets by altering intestinal flora associated bile acid metabolism and in turn regulating TGR-5/NF-κB/MLCK/MLC pathway.
Puerarin improves MASLD by remodeling intestinal microenvironment to promote mitochondrial fusion and autophagy.
Three-Dimensional Dynamic Blood-Brain Barrier Model Incorporating Native Cell Culture Systems Based on Shape Memory Biomaterials.
Network-based pharmacological and experimentally validated study on the therapeutic effects and mechanisms of Polygonatum Rhizoma Ginseng Formula in immunocompromised mice.
Enhanced alleviation of the selenite-grafted soluble and nondigestive Chinese Yam polysaccharides on nonylphenol-induced cytotoxicity and barrier damage in intestinal epithelial cells.
Probiotics may not adhere to gut and provide benefits in inflammatory bowel disease patients based on an AOM/DSS murine model.
Multiomics analysis revealed the effects of polystyrene nanoplastics at different environmentally relevant concentrations on intestinal homeostasis.
A derivative of tanshinone IIA and salviadione, 15a, inhibits inflammation and alleviates DSS-induced colitis in mice by direct binding and inhibition of RIPK2.
Exploring the Role of Gut Vascular Barrier Proteins in HIV-Induced Mucosal Damage: A Comparative Study.
The impact of combined thymol and rosmarinic acid on the intestinal microbiota and barrier function of the piglets challenged by Escherichia coli K88.
Polydatin, a derivative of resveratrol, ameliorates busulfan-induced oligozoospermia in mice by inhibiting NF-κB pathway activation and suppressing ferroptosis.
PIWI-interacting RNA MIABEPIR regulates cerebral endothelial cell function via DAPK2 pathway in offspring following maternal immune activation.
L-Arabinose Alleviates Functional Constipation in Mice by Regulating Gut Microbiota and Metabolites.
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Antihypertensive effects of rice peptides involve intestinal microbiome alterations and intestinal inflammation alleviation in spontaneously hypertensive rats.
Gancao Xiexin decoction attenuated experimental colitis through suppressing ACSL4-mediated ferroptosis.
Intranasal Delivery of Hydrophobic AC5216 Loaded Nanoemulsion into Brain To Alleviate Chronic Unpredictable Stress-Induced Depressive-like Behaviors.
VopX, a novel Vibrio cholerae T3SS effector, modulates host actin dynamics.
Taurine ameliorates deoxynivalenol-induced intestinal injury in piglets: Restoration of mitochondrial function linked to the PGC1α-NRF1/2 axis.
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
Milk Exosomes From Gestational Diabetes Mellitus Parturients Demonstrate Weaker Ability to Promote Intestinal Development in Offspring.
Blockade of A(2A)R improved brain perfusion and cognitive function in a mouse model of Alzheimer's disease.
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
Scutellaria baicalensis Extracts Restrict Intestinal Epithelial Cell Ferroptosis by Regulating Lipid Peroxidation and GPX4/ACSL4 in Colitis.
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Rag1(-/-) mice with T and B lymphocyte deficiency exhibit milder retinal inflammatory response and retinal ganglion cell injury after optic nerve crush.
Sesamin improved growth and overall health in young animals by enhancing gut-liver axis function.
Flos lonicerae polysaccharide alleviates inflammatory bowel disease by improving intestinal microbiota and inhibiting oxidative stress and the NF-κB pathway.
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
From TCM "Shen-nourishing" and "Yang-strengthening" theory to blood-testis barrier reorganization, GuiLuBuShen attenuates age-related male reproductive dysfunction.
Integrating transcriptomics, metabolomics, and microbiomics to explore the mechanism of action of bran-fried Atractylodes lancea rhizome polysaccharide in ameliorating the enhanced pharmacological effects of dextran sodium sulfate-induced colitis.
Echinacoside alleviates type 2 diabetes mellitus through inhibiting hepatic gluconeogenesis via gut bacterial-fungal trans-kingdom network reconstruction.
Music intervention mitigates LPS-induced gut barrier disruption and immune stress in broilers via TLR4/NF-κB regulation.
ShenQiGan Extract Repairs Intestinal Barrier in Weaning-Stressed Piglets by Modulating Inflammatory Factors, Immunoglobulins, and Short-Chain Fatty Acids.
The promoting effect of high-fat diet-induced trained immunity on ulcerative colitis and the mechanism of the therapeutic effect of Dahuang Mudan Decoction.
Nuciferine ameliorates blood-brain barrier disruption post-ischemic stroke via inhibiting the JAK2/STAT3 pathway.
Exploring the Mechanism of Kidney Injury in Mice Induced by High-Fat Diet and Polystyrene Nanoplastics Co-Exposure Through the Kidney-Gut Axis.
Kushenol I combats ulcerative colitis via intestinal barrier preservation and gut microbiota optimization.
Maternal lead exposure impairs offspring growth and intestinal microbiota via AMPK/ULK1 pathway activation.
Hyperoside promotes autophagy of colonic epithelial cells to protect intestinal barrier function in ulcerative colitis.
Wolfberry Honey and Its Extract Alleviate Dextran Sodium Sulfate-Induced Ulcerative Colitis by Improving Intestinal Barrier Function and Reducing Oxidative Stress and Inflammation.
Chronic arsenic exposure-provoked biotoxicity involved in liver-microbiota-gut axis disruption in chickens based on multi-omics technologies.
Discovery of a novel AhR-CYP1A1 axis activator for mitigating inflammatory diseases using an in situ functional imaging assay.
Ubiquitin-specific protease 25 ameliorates ulcerative colitis by regulating the degradation of phosphor-STAT3.
Mechanistic study of the effect of a high-salt diet on the intestinal barrier.
Interleukin 8 exacerbates age-related hearing loss through regulating perivascular-resident macrophage-like melanocytes viability and the permeability of the endothelial cells.
Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners.
Multi-omics analysis and experimental verification reveal testicular fatty acid metabolism disorder in non-obstructive azoospermia.
Neohesperidin Mitigates High-Fat-Diet-Induced Colitis In Vivo by Modulating Gut Microbiota and Enhancing SCFAs Synthesis.
Discovery of anti-inflammatory molecules from Dendrobium officinale based on activity labelled molecular networking and its alleviation effect on ulcerative colitis.
Xylooligosaccharide and Akkermansia muciniphila synergistically ameliorate insulin resistance by reshaping gut microbiota, improving intestinal barrier and regulating NKG2D/NKG2DL signaling in gestational diabetes mellitus mice.
Stigmasterol from Prunella vulgaris L. Alleviates LPS-induced mammary gland injury by inhibiting inflammation and ferroptosis.
Porphyromonas gingivalis and Its Outer Membrane Vesicles Induce Neuroinflammation in Mice Through Distinct Mechanisms.
Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway.
House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK/AP-1/IL-24 Signaling pathway in allergic rhinitis.
Treatment of Acute Ulcerative Colitis with Zinc Hyaluronate in Mice.
Bisdemethoxycurcumin and Curcumin Alleviate Inflammatory Bowel Disease by Maintaining Intestinal Epithelial Integrity and Regulating Gut Microbiota in Mice.
Polysaccharides from Lycium barbarum, yam, and sunflower ameliorate colitis in a structure and intrinsic flora-dependent manner.
Dietary baking soda (NaHCO(3)) therapy recovered urolithiasis-induced kidney injury in mice by inhibition of oxidative stress, pyroptosis, and inflammation through gut-kidney axis.
The T-type voltage-gated Ca(2+) channel Ca(V)3.1 involves in the disruption of respiratory epithelial barrier induced by Pasteurella multocida toxin.
The Protective Efficacy of Total Alkaloids from Nelumbinis Plumula on Irradiation-Induced Oxidative Stress Damage in Human Umbilical Vein Endothelial Cells.
A novel long-galanin peptide from non-mammalian vertebrates mitigates the inflammatory response in IBD models via the biased GALR2/β-arrestin2 pathway.
Embryonic exposure to GenX causes reproductive toxicity by disrupting the formation of the blood-testis barrier in mouse offspring.
Pristimerin Alleviates DSS-Induced Colitis in Mice by Modulating Intestinal Barrier Function, Gut Microbiota Balance and Host Metabolism.
Akkermansia muciniphila Akk11 Supplementation Attenuates MPTP-Induced Neurodegeneration by Inhibiting Microglial NLRP3 Inflammasome.
Targeting CD38 to alleviate brain endothelial cell dysfunction and cognitive impairment in vascular dementia.
Apigenin mitigates intestinal barrier dysfunction in sepsis by modulating the AKT signaling pathway.
Anti-Obesity Effects of Pea Peptides Modified by Steam Explosion on Obese Mice: Regulation of Gut Microbiota and Glucose Metabolism.
Liberation of galactose from lactose by gut microbial β-galactosidase prevents uterine bacterial infection.
Bifidobacterium species associated with breastfeeding alleviate neonatal hyperbilirubinaemia via the gut microbiota-α-linolenic and linoleic acid metabolism-enterohepatic circulation axis.
β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD(+)/SIRT1 signaling pathways.
Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome.
Podophyllotoxin Alleviates DSS-Induced Ulcerative Colitis via PI3K/AKT Pathway Activation.
Covalent Grafting of Inorganic Selenium to the Water-Soluble and Nondigestive Chinese Yam Polysaccharides Causes Greater Protection of IEC-6 Cells with Acrylamide Injury.
Card9 deficiency exacerbates vulvovaginal candidiasis by impairing the IL-17 production and vaginal epithelial barrier.
HFD-induced LPS translocation and elevated blood lipids exacerbated the inflammatory response in allergic rhinitis.
Total ginsenosides from wild ginseng improve immune regulation in a rat model of spleen qi deficiency by modulating fecal-bacteria-associated short-chain fatty acids and intestinal barrier integrity.
Lactobacillus paracasei Expressing Porcine Trefoil Factor 3 and Epidermal Growth Factor: A Novel Approach for Superior Mucosal Repair.
Exercise antagonizes cadmium-caused liver and intestinal injury in mice via Nrf2 and TLR2/NF-κB signalling pathway.
Cell Membrane-Coated Nanotherapeutics for the Targeted Treatment of Acute and Chronic Colitis.
Therapeutic Effects of Lifei Decoction in a Murine Model of COPD Induced by LPS and Cigarette Smoke.
Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB.
Fusobacterium Nucleatum Aggravates Intestinal Barrier Impairment and Colitis Through IL-8 Induced Neutrophil Chemotaxis by Activating Epithelial Cells.
Cistanche deserticola polysaccharide alleviates constipation by regulating intestinal barrier function and intestinal microbiota and their metabolites.
Periplanta americana extract regulates the Th17/Treg cell balance via Notch1 in ulcerative colitis.
Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.
Different effects of acute and chronic oxidative stress on the intestinal flora and gut-liver axis in weaned piglets.
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Coactosin-like protein 1 regulates integrity and repair of model intestinal epithelial barriers via actin binding dependent and independent mechanisms.
Molecular hydrogen supplementation in mice ameliorates lipopolysaccharide-induced loss of interest.
Lactobacillus gasseri ATCC33323 affects the intestinal mucosal barrier to ameliorate DSS-induced colitis through the NR1I3-mediated regulation of E-cadherin.
Ningxiang pig-derived Enterococcus hirae HNAU0516 ameliorates postweaning diarrhoea by promoting intestinal health and modulating the gut microbiota in piglets.
Long-Term Exposure to Polystyrene Microspheres and High-Fat Diet-Induced Obesity in Mice: Evaluating a Role for Microbiota Dysbiosis.
Sanfeng Tongqiao Dripping Pills alleviate House Dust Mite-induced allergic rhinitis in mice by inhibiting Th2 differentiation and repairing the nasal epithelial barrier.
Paeoniae Decoction restores intestinal barrier dysfunction by promoting the interaction between ILC3 and gut flora.
Theabrownin from Pu-erh Tea Improves DSS-Induced Colitis via Restoring Gut Homeostasis and Inhibiting TLR2&4 Signaling Pathway.
Berberine and magnolol exert cooperative effects on ulcerative colitis in mice by self-assembling into carrier-free nanostructures.
Knockdown of HSPA13 Inhibits TGFβ1-Induced Epithelial-Mesenchymal Transition of RPE by Suppressing the PI3K/Akt Signaling Pathway.
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
hucMSC-Ex alleviates inflammatory bowel disease in mice by enhancing M2-type macrophage polarization via the METTL3-Slc37a2-YTHDF1 axis.
MicroRNA-522-3p promotes brain metastasis in non-small cell lung cancer by targeting Tensin 1 and modulating blood-brain barrier permeability.
Combined effects of TiO(2) nanoparticle and fipronil co-exposure on microbiota in mouse intestine.
PPARγ/NF-κB axis contributes to cold-induced resolution of experimental colitis and preservation of intestinal barrier.
Protective Effect of Protocatechuic Aldehyde on Cerebral Ischemia/Reperfusion Injury in Rats through Blood-Brain Barrier Protection.
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
Kiwifruit Polysaccharides Alleviate Ulcerative Colitis via Regulating Gut Microbiota-Dependent Tryptophan Metabolism and Promoting Colon Fucosylation.
Gut Lactococcus garvieae promotes protective immunity to foodborne Clostridium perfringens infection.
DHA-enriched phosphatidylserine ameliorates cyclophosphamide-induced liver injury via regulating the gut-liver axis.
WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis.
Therapeutic Potential of Foodborne Indole Derived from Chinese Stinky Tofu in Reducing Intestinal Inflammation and Enhancing Barrier Function to Mitigate Alcoholic Liver Injury.
Identification of COL3A1 as a candidate protein involved in the crosstalk between obesity and diarrhea using quantitative proteomics and machine learning.
Increased SPARC in brain microvessels of ob/ob mice accelerates molecular transport into the brain accompany with albumin.
NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice.
Cadmium Induces Vascular Endothelial Cell Detachment by Downregulating Claudin-5 and ZO-1 Levels.
Yam protein ameliorates cyclophosphamide-induced intestinal immunosuppression by regulating gut microbiota and its metabolites.
Human placental mesenchymal stem cells transplantation repairs the alveolar epithelial barrier to alleviate lipopolysaccharides-induced acute lung injury.
Oridonin alleviates cigarette smoke-induced nasal polyp formation by promoting autophagy.
The role of the microbiota-gut-brain axis in methamphetamine-induced neurotoxicity: Disruption of microbial composition and short-chain fatty acid metabolism.
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
The gut microbial metabolite indole-3-aldehyde alleviates impaired intestinal development by promoting intestinal stem cell expansion in weaned piglets.
Gut commensal Parabacteroides distasonis exerts neuroprotective effects in acute ischemic stroke with hyperuricemia via regulating gut microbiota-gut-brain axis.
Differential Roles of Astrocytic CSF1 in Alzheimer's Disease and Cerebral Amyloid Angiopathy: Insights from Transcriptomic Analysis.
The Hydrophobic Amino Acid-Rich Fish Collagen Peptide Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice via Repairing the Intestinal Barrier, Regulating Intestinal Flora and AA Metabolism.
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Unveiling the Novel Benefits of Co-Administering Butyrate and Active Vitamin D3 in Mice Subjected to Chemotherapy-Induced Gut-Derived Pseudomonas aeruginosa Sepsis.
The rhizomes of Atractylodes macrocephala Koidz improve gastrointestinal health and pregnancy outcomes in pregnant mice via modulating intestinal barrier and water-fluid metabolism.
Shaoyao decoction improves damp-heat colitis by activating the AHR/IL-22/STAT3 pathway through tryptophan metabolism driven by gut microbiota.
miRNA Expression Analysis of IPEC-J2 Cells Damaged by Soybean 7S Globulin Reveals ssc-miR-221-5p as the Factor Alleviating Cell Damage.
Tryptophan metabolites relieve intestinal Candida albicans infection by altering the gut microbiota to reduce IL-22 release from group 3 innate lymphoid cells of the colon lamina propria.
Nicotinamide Supplementation Mitigates Oxidative Injury of Bovine Intestinal Epithelial Cells through Autophagy Modulation.
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
The therapeutic effects of traditional Chinese medicine on insulin resistance in obese mice by modulating intestinal functions.
High-intensity exercise impairs intestinal barrier function by generating oxidative stress.
Narirutin Attenuates Cerebral Ischemia-Reperfusion Injury by Suppressing the TXNIP/NLRP3 Pathway.
Suppression of neutrophil extracellular traps is responsible for the amelioration of chemotherapeutic intestinal injury by the natural compound PEITC.
Inhibition of EphA4 reduces vasogenic edema after experimental stroke in mice by protecting the blood-brain barrier integrity.
OR11H1 Missense Variant Confers the Susceptibility to Vogt-Koyanagi-Harada Disease by Mediating Gadd45g Expression.
Interleukin-22 Contributes to Blood-Brain Barrier Disruption via STAT3/VEGFA Activation in Escherichia coli Meningitis.
Xylooligosaccharides ameliorate insulin resistance by increasing Akkermansia muciniphila and improving intestinal barrier dysfunction in gestational diabetes mellitus mice.
Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline-Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora.
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis.
Sulforaphane decreases oxidative stress and inhibits NLRP3 inflammasome activation in a mouse model of ulcerative colitis.
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.
Paeoniflorin ameliorates chronic colitis via the DR3 signaling pathway in group 3 innate lymphoid cells.
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways.
Sarcandra glabra (Thunb.) Nakai alleviates DSS-induced ulcerative colitis by promoting restitution, restoring barrier function, and modulating IL-17/Notch1/FoxP3 pathway in intestinal cells.
Fucoxanthin alleviates lipopolysaccharide-induced intestinal barrier injury in mice.
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy.
Exposure to hexa(fl)uoropropylene oxide trimer acid (HFPO-TA) impairs 5-HT metabolism by impacting the brain-gut axis in mice.
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
The Use of Polysaccharide AOP30 from the Rhizome of Alpinia officinarum Hance to Alleviate Lipopolysaccharide-Induced Intestinal Epithelial Barrier Dysfunction and Inflammation via the TLR4/NfκB Signaling Pathway in Caco-2 Cell Monolayers.
Study on the mechanism of mitigating radiation damage by improving the hematopoietic system and intestinal barrier with Tenebrio molitor peptides.
Simultaneous ischemic regions targeting and BBB crossing strategy to harness extracellular vesicles for therapeutic delivery in ischemic stroke.
PSD-95 inhibitor Tat-NR2B9c (NA-1) protects the integrity of the blood-brain barrier after transient middle artery occlusion in rats by downregulating matrix metalloprotease-9 and upregulating endothelial nitric oxide synthase.
Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken.
Inhibition of circulating exosomes release with GW4869 mitigates severe acute pancreatitis-stimulated intestinal barrier damage through suppressing NLRP3 inflammasome-mediated pyroptosis.
The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway.
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
Canonical and Non-Canonical Localization of Tight Junction Proteins during Early Murine Cranial Development.
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.
Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis.
Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway.
Baitouweng decoction repairs the intestinal barrier in DSS-induced colitis mice via regulation of AMPK/mTOR-mediated autophagy.
Gut Microbiota Plays Essential Roles in Soyasaponin's Preventive Bioactivities against Steatohepatitis in the Methionine and Choline Deficient (MCD) Diet-Induced Non-Alcoholic Steatohepatitis (NASH) Mice.
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
Neuron Derived Cold-Inducible RNA-Binding Protein Promotes NETs Formation to Exacerbate Brain Endothelial Barrier Disruption after Ischemic Stroke.
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice.
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.
The microbial metabolite urolithin A reduces Clostridioides difficile toxin expression and toxin-induced epithelial damage.
Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway.
Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis.
Inulin alleviates perfluorooctanoic acid-induced intestinal injury in mice by modulating the PI3K/AKT/mTOR signaling pathway.
Rehmannia glutinosa polysaccharides enhance intestinal immunity of mice through regulating the microbiota.
Ganjiang Huangqin Huanglian Renshen Decoction protects against ulcerative colitis by modulating inflammation, oxidative stress, and gut microbiota.
Resistant starch confers protection of dietary against diabetic cardiomyopathy.
An In Vitro Model of the Blood-Brain Barrier for the Investigation and Isolation of the Key Drivers of Barriergenesis.
Therapeutic Efficacy and Underlying Mechanisms of a Mannoglucan from Hirsutella sinensis Mycelium on Dextran Sulfate Sodium-Induced Inflammatory Bowel Disease in Mice: Modulation of the Intestinal Barrier, Oxidative Stress and Gut Microbiota.
FGF20 modulates gut microbiota to mitigate dextran sodium sulfate-induced ulcerative colitis in mouse models.
Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability.
Inulin alleviates GenX-induced intestinal injury in mice by modulating the MAPK pathway, cell cycle, and cell adhesion proteins.
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
Role of transient receptor potential vanilloid 4 channels in an ovalbumin-induced murine food allergic model.
Gut microbiota is necessary for pair-housing to protect against post-stroke depression in mice.
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
Chitosan-alginate/R8 ternary polyelectrolyte complex as an oral protein-based vaccine candidate induce effective mucosal immune responses.
The dual effects of dexmedetomidine on intestinal barrier and intestinal motility during sepsis.
Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration.
Nur77 as a novel regulator of Paneth cell differentiation and function.
The Phospholipid Flippase ATP8B1 is Involved in the Pathogenesis of Ulcerative Colitis via Establishment of Intestinal Barrier Function.
Butylparaben induces glycolipid metabolic disorders in mice via disruption of gut microbiota and FXR signaling.
Indole-3-aldehyde Alleviates High-Fat Diet-Induced Gut Barrier Disruption by Increasing Intestinal Stem Cell Expansion.
Dietary rutin improves the antidiarrheal capacity of weaned piglets by improving intestinal barrier function, antioxidant capacity and cecal microbiota composition.
Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology.
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
Qing-Re-Chu-shi decoction ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice through anti-inflammation and immunoregulatory mechanisms.
Exploring the mechanism of Bushen Huoxue prescription in the treatment of early diabetic retinal edema from the perspective of inner blood-retinal barrier injury.
Canagliflozin protects against hyperglycemia-induced cerebrovascular injury by preventing blood-brain barrier (BBB) disruption via AMPK/Sp1/adenosine A2A receptor.
Tetrandrine Inhibits Cancer Stem Cell Characteristics and Epithelial to Mesenchymal Transition in Triple-Negative Breast Cancer via SOD1/ROS Signaling Pathway.
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell Activity.
Mahuang Fuzi Xixin decoction ameliorates allergic rhinitis and repairs the airway epithelial barrier by modulating the lung microbiota dysbiosis.
Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.
Circulating sepsis-related metabolite sphinganine could protect against intestinal damage during sepsis.
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury.
Maslinic acid alleviates LPS-induced mice mastitis by inhibiting inflammatory response, maintaining the integrity of the blood-milk barrier and regulating intestinal flora.
Mitigation of maternal fecal microbiota transplantation on neurobehavioral deficits of offspring rats prenatally exposed to arsenic: Role of microbiota-gut-brain axis.
DUOX2-Induced Oxidative Stress Inhibits Intestinal Angiogenesis through MMP3 in a Low-Birth-Weight Piglet Model.
Resveratrol alleviates DSS-induced IBD in mice by regulating the intestinal microbiota-macrophage-arginine metabolism axis.
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Treatment with Ligilactobacillus murinus lowers blood pressure and intestinal permeability in spontaneously hypertensive rats.
Effects of DON on Mitochondrial Function, Endoplasmic Reticulum Stress, and Endoplasmic Reticulum Mitochondria Contact Sites in the Jejunum of Piglets.
Cerebrospinal Fluid Pressure Reduction Induces Glia-Mediated Retinal Inflammation and Leads to Retinal Ganglion Cell Injury in Rats.
Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans.
Iguratimod promotes functional recovery after SCI by repairing endothelial cell tight junctions.
Lactiplantibacillus plantarum Strain FLPL05 Promotes Longevity in Mice by Improving Intestinal Barrier.
Lauric acid provides neuroprotection against oxidative stress in mouse model of hyperglycaemic stroke.
Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier.
Atractylodes lancea Rhizome Polysaccharide Alleviates Immunosuppression and Intestinal Mucosal Injury in Mice Treated with Cyclophosphamide.
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Role of SIRT2 in intestinal barrier under cold exposure.
Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin).
Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis.
Fecal microbiota transplantation combined with prebiotics ameliorates ulcerative colitis in mice.
Kaempferol ameliorated alcoholic liver disease through inhibiting hepatic bile acid synthesis by targeting intestinal FXR-FGF15 signaling.
Aqueous Extract of Brassica rapa L.'s Impact on Modulating Exercise-Induced Fatigue via Gut-Muscle Axis.
Cingulin regulates hair cell cuticular plate morphology and is required for hearing in human and mouse.
PE (0:0/14:0), an endogenous metabolite of the gut microbiota, exerts protective effects against sepsis-induced intestinal injury by modulating the AHR/CYP1A1 pathway.
Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions.
Chloroquine Protects Hypoxia/Ischemia-Induced Neonatal Brain Injury in Rats by Mitigating Blood-Brain Barrier Disruption.
Cysteamine and N-Acetyl-cysteine Alleviate Placental Oxidative Stress and Barrier Function Damage Induced by Deoxynivalenol.
Molecular Mechanisms Associated with Protecting IEC-6 Cells from Acrylamide-Induced Tight Junction Damage by Ganoderma atrum Polysaccharide.
The Polo-Like Kinase 1-Mammalian Target of Rapamycin Axis Regulates Autophagy to Prevent Intestinal Barrier Dysfunction During Sepsis.
Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation.
Cimifugin suppresses type 2 airway inflammation by binding to SPR and regulating its protein expression in a non-enzymatic manner.
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Foodborne Carbon Dot Exposure Induces Insulin Resistance through Gut Microbiota Dysbiosis and Damaged Intestinal Mucus Layer.
Beneficial Effects of Hordenine on a Model of Ulcerative Colitis.
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Chitosan oligosaccharide alleviates and removes the toxicological effects of organophosphorus pesticide chlorpyrifos residues.
Compatibility between cold-natured medicine CP and hot-natured medicine AZ synergistically mitigates colitis mice through attenuating inflammation and restoring gut barrier.
Therapeutic effects of Zhuling Jianpi capsule on experimental ulcerative colitis and characterization of its chemical constituents and metabolomics using UHPLC-Q-TOF-MS.
Circulating exosomal miR-155-5p contributes to severe acute pancreatitis-associated intestinal barrier injury by targeting SOCS1 to activate NLRP3 inflammasome-mediated pyroptosis.
Non-Invasive and Label-Free On-Chip Impedance Monitoring of Heatstroke.
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic Methamphetamine Exposure.
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis.
Sodium butyrate ameliorates diabetic retinopathy in mice via the regulation of gut microbiota and related short-chain fatty acids.
Open source board based acoustofluidic transwells for reversible disruption of the blood-brain barrier for therapeutic delivery.
Astrocytes in the spinal cord contributed to acute stress-induced gastric damage via the gap junction protein CX43.
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation.
Apelin-13 prevents the effects of oxygen-glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT-mTOR signaling.
Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.
Effects of thiacloprid exposure on microbiota-gut-liver axis: Multiomics mechanistic analysis in Japanese quails.
Pulsatilla decoction improves DSS-induced colitis via modulation of fecal-bacteria-related short-chain fatty acids and intestinal barrier integrity.
β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota.
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
PLK1 protects intestinal barrier function in sepsis: A translational research.
DHA-enriched phosphatidylserine alleviates high fat diet-induced jejunum injury in mice by modulating gut microbiota.
Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1-CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice.
Fecal microbiota transplantation attenuates Escherichia coli infected outgrowth by modulating the intestinal microbiome.
Disorders in the gut and liver are involved in depression contagion between isosexual post-stroke depression mice and the healthy cohabitors.
Small molecule compound K-7174 attenuates neuropsychiatric manifestations in lupus-prone mice.
Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.
Effects of Houpo Mahuang Decoction on serum metabolism and TRPV1/Ca(2+)/TJs in asthma.
Piceatannol and 3'-Hydroxypterostilbene Alleviate Inflammatory Bowel Disease by Maintaining Intestinal Epithelial Integrity and Regulating Gut Microbiota in Mice.
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
A new microphysiological system shows hypoxia primes human ISCs for interleukin-dependent rescue of stem cell activity.
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Astragaloside IV ameliorate acute alcohol-induced liver injury in mice via modulating gut microbiota and regulating NLRP3/caspase-1 signaling pathway.
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Assessment of intestinal status in MPL(W515L) mutant myeloproliferative neoplasms mice model.
Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells.
Protocol for identifying physiologically relevant binding proteins of G-protein-coupled receptors.
A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS.
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
PRMT7 can prevent neurovascular uncoupling, blood-brain barrier permeability, and mitochondrial dysfunction in repetitive and mild traumatic brain injury.
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Targeting formyl peptide receptor 1 with anteiso-C13-surfactin for neutrophil-dominant acute respiratory distress syndrome.
Holothurian Wall Hydrolysate Ameliorates Cyclophosphamide-Induced Immunocompromised Mice via Regulating Immune Response and Improving Gut Microbiota.
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc.
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice.
Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of ADAM17.
Interaction between GPR110 (ADGRF1) and tight junction protein occludin implicated in blood-brain barrier permeability.
Ginkgo biloba Extract Preventively Intervenes in Citrobacter Rodentium-Induced Colitis in Mice.
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Pterostilbene attenuates intestinal epithelial barrier loss induced by high loading intensity of exercise.
Probiotic Lactobacillus rhamnosus GR-1 supplementation attenuates Pb-induced learning and memory deficits by reshaping the gut microbiota.
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Effects of Lipolysis-Stimulated Lipoprotein Receptor on Tight Junctions of Pancreatic Ductal Epithelial Cells in Hypertriglyceridemic Acute Pancreatitis.
Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Tryptophan Supplementation Enhances Intestinal Health by Improving Gut Barrier Function, Alleviating Inflammation, and Modulating Intestinal Microbiome in Lipopolysaccharide-Challenged Piglets.
Effect of Tanshinone IIA on Gut Microbiome in Diabetes-Induced Cognitive Impairment.
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis.
Liujunanwei decoction attenuates cisplatin-induced nausea and vomiting in a Rat-Pica model partially mediated by modulating the gut micsrobiome.
Effects of Zhishi Daozhi Decoction on the intestinal flora of nonalcoholic fatty liver disease mice induced by a high-fat diet.
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
GLP-1 receptor nitration contributes to loss of brain pericyte function in a mouse model of diabetes.
Dihydroartemisinin protects blood-brain barrier permeability during sepsis by inhibiting the transcription factor SNAI1.
Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis.
BMP2 promotes lung adenocarcinoma metastasis through BMP receptor 2-mediated SMAD1/5 activation.
The Barrier-Enhancing Function of Soluble Yam (Dioscorea opposita Thunb.) Polysaccharides in Rat Intestinal Epithelial Cells as Affected by the Covalent Se Conjugation.
Probing the Potential Mechanism of Quercetin and Kaempferol against Heat Stress-Induced Sertoli Cell Injury: Through Integrating Network Pharmacology and Experimental Validation.
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Effect and Mechanism of Pharmaceutical Excipients on Berberine to Alleviate Ulcerative Colitis via Regulating Gut Microbiota.
Phytic Acid Improves Hepatic Steatosis, Inflammation, and Oxidative Stress in High-Fat Diet (HFD)-Fed Mice by Modulating the Gut-Liver Axis.
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Rice Protein Peptides Alleviate Dextran Sulfate Sodium-Induced Colitis via the Keap1-Nrf2 Signaling Pathway and Regulating Gut Microbiota.
Network Pharmacology Analysis and Experimental Validation of Kaempferol in the Treatment of Ischemic Stroke by Inhibiting Apoptosis and Regulating Neuroinflammation Involving Neutrophils.
Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema.
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Luteolin alleviates ulcerative colitis by restoring the balance of NCR(-)ILC3/NCR(+)ILC3 to repairing impaired intestinal barrier.
Natural borneol enhances the anti-cerebral ischaemia efficacy of formononetin in MCAO/R rats by promoting its delivery in the brain.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Live and pasteurized Akkermansia muciniphila attenuate hyperuricemia in mice through modulating uric acid metabolism, inflammation, and gut microbiota.
New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway.
Senegalia macrostachya seed polysaccharides attenuate inflammation-induced intestinal epithelial barrier dysfunction in a Caco-2 and RAW264.7 macrophage co-culture model by inhibiting the NF-κB/MLCK pathway.
DHA-enriched phosphatidylcholine from Clupea harengus roes regulates the gut-liver axis to ameliorate high-fat diet-induced non-alcoholic fatty liver disease.
Hippocampal Activated Microglia May Contribute to Blood-Brain Barrier Impairment and Cognitive Dysfunction in Post-Traumatic Stress Disorder-Like Rats.
A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair.
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Galactooligosaccharides as a protective agent for intestinal barrier and its regulatory functions for intestinal microbiota.
Effect of dendrobium mixture in alleviating diabetic cognitive impairment associated with regulating gut microbiota.
Dietary Alpha-Ketoglutarate Partially Abolishes Adverse Changes in the Small Intestine after Gastric Bypass Surgery in a Rat Model.
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Dietary ferulic acid and vanillic acid on inflammation, gut barrier function and growth performance in lipopolysaccharide-challenged piglets.
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates DSS-induced intestinal colitis by improving intestinal mucosal barrier function.
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis.
Protective role of casuarinin from Melastoma malabathricum against a mouse model of 5-fluorouracil-induced intestinal mucositis: Impact on inflammation and gut microbiota dysbiosis.
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Effect of Houpo-Mahuang Decoction on aggravated asthma induced by cigarette smoke and the expression of TRPA1 and tight junctions in mice.
Selenium exerts protective effects against heat stress-induced barrier disruption and inflammation response in jejunum of growing pigs.
Gualou Xiebai Decoction ameliorates increased Caco-2 monolayer permeability induced by bile acids via tight junction regulation, oxidative stress suppression and apoptosis reduction.
Effects of Exopolysaccharides from Lactiplantibacillus plantarum JLAU103 on Intestinal Immune Response, Oxidative Stress, and Microbial Communities in Cyclophosphamide-Induced Immunosuppressed Mice.
Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway.
Decreased ZO1 expression causes loss of time-dependent tight junction function in the liver of ob/ob mice.
Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut-lung axis.
Effects of betaine on viability, apoptosis, function protein expression and oxidative status in heat-stressed IEC-6 cells.
Huang Qin Decoction inhibits the initiation of experimental colitis associated carcinogenesis by controlling the PAD4 dependent NETs.
Dahuang Mudan decoction repairs intestinal barrier in chronic colitic mice by regulating the function of ILC3.
Glutathione Protects against Paraquat-Induced Oxidative Stress by Regulating Intestinal Barrier, Antioxidant Capacity, and CAR Signaling Pathway in Weaned Piglets.
Effect of ginsenoside compound K on alleviating colitis via modulating gut microbiota.
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Efficacy and Mechanism of Quercetin in the Treatment of Experimental Colitis Using Network Pharmacology Analysis.
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Chitosan-modified Phellinus igniarius polysaccharide PLGA nanoparticles ameliorated inflammatory bowel disease.
Protective effect of surface-layer proteins from four Lactobacillus strains on tumor necrosis factor-α-induced intestinal barrier dysfunction.
Neohesperidin Dihydrochalcone Ameliorates High-Fat Diet-Induced Glycolipid Metabolism Disorder in Rats.
Urolithin A attenuates arsenic-induced gut barrier dysfunction.
P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer.
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota.
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff.
Evaluation of the Anti-Aging Effects of a Probiotic Combination Isolated From Centenarians in a SAMP8 Mouse Model.
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease.
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Diallyl Disulfide (DADS) Ameliorates Intestinal Candida albicans Infection by Modulating the Gut microbiota and Metabolites and Providing Intestinal Protection in Mice.
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon.
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Sucralose enhances the susceptibility to dextran sulfate sodium (DSS) induced colitis in mice with changes in gut microbiota.
Influences of Xylitol Consumption at Different Dosages on Intestinal Tissues and Gut Microbiota in Rats.
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Rho-kinase inhibitor hydroxyfasudil protects against HIV-1 Tat-induced dysfunction of tight junction and neprilysin/Aβ transfer receptor expression in mouse brain microvessels.
Alterations in the gut microbiota and metabolic profiles coincide with intestinal damage in mice with a bloodborne Candida albicans infection.
Effects of Qing Hua Chang Yin on lipopolysaccharide‑induced intestinal epithelial tight junction injury in Caco‑2 cells.
Suppression of obesity and inflammation by polysaccharide from sporoderm-broken spore of Ganoderma lucidum via gut microbiota regulation.
Oral delivery of staphylococcal nuclease ameliorates DSS induced ulcerative colitis in mice via degrading intestinal neutrophil extracellular traps.
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Effects of cigarette smoke on the aggravation of ovalbumin-induced asthma and the expressions of TRPA1 and tight junctions in mice.
TNF-α released from retinal Müller cells aggravates retinal pigment epithelium cell apoptosis by upregulating mitophagy during diabetic retinopathy.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Xinhuang Tablets Improve Intestinal Barrier Function via Regulating Epithelial Tight Junctions in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice.
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation.
Polystyrene microplastics induced male reproductive toxicity in mice.
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Xianglian Pill ameliorates antibiotic-associated diarrhea by restoring intestinal microbiota and attenuating mucosal damage.
Combination of Mesenchymal Stem Cell and Endothelial Progenitor Cell Infusion Accelerates Injured Intestinal Repair by Regulating Gut Microbiota after Hematopoietic Cell Transplantation.
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Titanium dioxide nanoparticles perturb the blood-testis barrier via disruption of actin-based cell adhesive function.
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Increase of BACE1, Brain-Renal Risk Factor, Contributes to Kidney Damage in an Alzheimer's Disease Mouse Model.
Changes of Gut Microbiota and Its Correlation With Short Chain Fatty Acids and Bioamine in Piglets at the Early Growth Stage.
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Isolation of Mouse Cerebral Microvasculature for Molecular and Single-Cell Analysis.
Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells.
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Dietary Copper Plays an Important Role in Maintaining Intestinal Barrier Integrity During Alcohol-Induced Liver Disease Through Regulation of the Intestinal HIF-1α Signaling Pathway and Oxidative Stress.
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.
Sucralose Promotes Colitis-Associated Colorectal Cancer Risk in a Murine Model Along With Changes in Microbiota.
Salmonella Effector SpvB Disrupts Intestinal Epithelial Barrier Integrity for Bacterial Translocation.
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Interferon-β alleviates delayed tPA-induced adverse effects via modulation of MMP3/9 production in ischemic stroke.
Claudin 1 inhibits cell migration and increases intercellular adhesion in triple-negative breast cancer cell line.
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Dl-3-n-butylphthalide attenuates hypoxic-ischemic brain injury through inhibiting endoplasmic reticulum stress-induced cell apoptosis and alleviating blood-brain barrier disruption in newborn rats.
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Assessment of oral ciprofloxacin impaired gut barrier integrity on gut bacteria in mice.
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts.
Maternal Exposure to Di-n-butyl Phthalate Promotes the Formation of Testicular Tight Junctions through Downregulation of NF-κB/COX-2/PGE(2)/MMP-2 in Mouse Offspring.
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia.
A Novel Pharmacological Approach to Enhance the Integrity and Accelerate Restitution of the Intestinal Epithelial Barrier.
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke.
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
The Functional Role of Fecal Microbiota Transplantation on Dextran Sulfate Sodium-Induced Colitis in Mice.
Puerarin prevents high-fat diet-induced obesity by enriching Akkermansia muciniphila in the gut microbiota of mice.
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Characterization of a Novel Diarrheagenic Strain of Proteus mirabilis Associated With Food Poisoning in China.
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner.
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Intestinal epithelial PKM2 serves as a safeguard against experimental colitis via activating β-catenin signaling.
The protective effect of selenium from heat stress-induced porcine small intestinal epithelial cell line (IPEC-J2) injury is associated with regulation expression of selenoproteins.
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Bacterial β-glucuronidase alleviates dextran sulfate sodium-induced colitis in mice: A possible crucial new diagnostic and therapeutic target for inflammatory bowel disease.
Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions.
Fasudil alleviates LPS-induced lung injury by restoring aquaporin 5 expression and inhibiting inflammation in lungs.
Newly synthesized claudins but not occludin are added to the basal side of the tight junction.
Propofol attenuated TNF-α-modulated occludin expression by inhibiting Hif-1α/ VEGF/ VEGFR-2/ ERK signaling pathway in hCMEC/D3 cells.
SET domain containing protein 5 (SETD5) enhances tumor cell invasion and is associated with a poor prognosis in non-small cell lung cancer patients.
KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis.
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer.
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Effects of dietary supplementation with Lactobacillus acidophilus on the performance, intestinal physical barrier function, and the expression of NOD-like receptors in weaned piglets.
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
Probiotic Mixture Protects Dextran Sulfate Sodium-Induced Colitis by Altering Tight Junction Protein Expressions and Increasing Tregs.
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB.
Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood-brain barrier's tight junction proteins.
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Nasal epithelial barrier disruption by particulate matter ≤2.5 μm via tight junction protein degradation.
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation.
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea.
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
MARCKS-related protein regulates cytoskeletal organization at cell-cell and cell-substrate contacts in epithelial cells.
Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage.
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Deficiency in intestinal epithelial O-GlcNAcylation predisposes to gut inflammation.
Arsenic-Induced Autophagy in the Developing Mouse Cerebellum: Involvement of the Blood-Brain Barrier's Tight-Junction Proteins and the PI3K-Akt-mTOR Signaling Pathway.
Endoplasmic Reticulum Stress Mediates Methamphetamine-Induced Blood-Brain Barrier Damage.
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity.
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Metformin treatment after the hypoxia-ischemia attenuates brain injury in newborn rats.
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
Pro-apoptotic effect of Δ2-TGZ in "claudin-1-low" triple-negative breast cancer cells: involvement of claudin-1.
Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion.
Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells.
6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling.
Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-κB signaling pathway after LPS treatment in neonatal rats.
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
Oral administration of propionic acid during lactation enhances the colonic barrier function.
Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood-Brain Barrier after Cerebral Ischemia Reperfusion Injury.
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
RCCD1 depletion attenuates TGF-β-induced EMT and cell migration by stabilizing cytoskeletal microtubules in NSCLC cells.
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus.
Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice.
Effects of Bacillus subtilis on Epithelial Tight Junctions of Mice with Inflammatory Bowel Disease.
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.
Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice.
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Activation of G protein-coupled estrogen receptor 1 (GPER-1) ameliorates blood-brain barrier permeability after global cerebral ischemia in ovariectomized rats.
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.
Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice.
Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role.
Notch1 signaling regulates the epithelial-mesenchymal transition and invasion of breast cancer in a Slug-dependent manner.
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Ni J, Zhang R, Pu Y, He Y, Hu W, Su L, Hou Y, Dou H
International journal of biological sciences 2026;22(1):239-257
International journal of biological sciences 2026;22(1):239-257
Ulinastatin attenuates capillary leakage and suppresses FoxO1-dependent angiopoietin-2 in sepsis-associated acute lung injury via PI3K pathway.
Lv Y, Meng Y, Rui H, Li T, Zhang J, Liu J, Ma X, Wang J, Yuan Y, Jiang Y, Yan X, Li M, Dong X, Zhang B, Ma L
PloS one 2026;21(4):e0348261
PloS one 2026;21(4):e0348261
miR-329-3p derived from mast cells-exosomes exacerbates intestinal ischemia-reperfusion injury by targeting ATG10 to regulate autophagy.
Liang Y, Sheng R, Deng H, Huang D, Xu K, Wang Y, Liu D
International journal of biological macromolecules 2026 May;361:152091
International journal of biological macromolecules 2026 May;361:152091
Faecalibacterium prausnitzii: A microbial ally against preeclampsia via extracellular vesicle-mediated ferroptosis inhibition.
Zhang W, Lai W, Peng M, Yu L, Nie Y, Deng Y
Free radical biology & medicine 2026 May;248:333-349
Free radical biology & medicine 2026 May;248:333-349
Chaihu-Shugan San ameliorates perimenopausal obesity with depression by coordinately targeting hepatic PGC-1α/CYP8B1/PPARγ signaling and gut barrier integrity.
Chen Q, Liu J, Wang J, Yin T, Wu Y, Zhang T, Yu F
Journal of ethnopharmacology 2026 May 23;363:121407
Journal of ethnopharmacology 2026 May 23;363:121407
Geometrically Constrained Growth Factor Concentration Favors Enrichment of Goblet Cells and Mucus Formation.
Villegas-Novoa C, Wang Y, Wang H, Jan I, Sims CE, Allbritton NL
ACS biomaterials science & engineering 2026 May 11;12(5):2700-2713
ACS biomaterials science & engineering 2026 May 11;12(5):2700-2713
Nitric Oxide Donor Alleviates Cardiac Arrest Induced Blood Brain Barrier Injury by Inhibiting HMGB1-ATG5 Mediated Endothelial Autophagy.
Duan P, Bi Y, Feng W, Jin Z, Meng Y, Li H, Li X, Luo L, Zhao X, Zhang B
Cellular and molecular neurobiology 2026 Mar 6;46(1)
Cellular and molecular neurobiology 2026 Mar 6;46(1)
ALKBH5 facilitates Srgn stability via m6A demethylation to disrupt blood-testis barrier integrity in the high-fat diet mice.
Du T, Yao L, Wang W, Li Z, Dong J, Zhou Z, Shi C, Ge X, Ma R, Chen L, Xiang Y, He Z, Zheng L, Xu Y, Cao C, Jing J, Ma J, Yao B
Cellular and molecular life sciences : CMLS 2026 Mar 30;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 30;83(1)
Tumor-Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis.
Yu S, Zhuo J, Hong X, Rao S, Ye Y, Kang D, Peng H, Zhuo H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 13;:e21962
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 13;:e21962
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
Yue M, Chen T, Chen W, Wei J, Liao B, Zhang J, Li F, Hong D, Fang X
Neural regeneration research 2026 Mar 1;21(3):1211-1221
Neural regeneration research 2026 Mar 1;21(3):1211-1221
Senkyunolide I attenuates radiation-induced cognitive dysfunction by restoring PINK1-Parkin-mediated mitophagy and redox homeostasis.
Yan T, Guo S, Zhang S, Wang Q, Zhang Z, Zhao W, Li X, Lai N, Jiang W, Xu Y, Yang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158136
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158136
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
Cen Q, Cui Y, Feng J, Zhu L, Wei J, Wang L, Chang C, Pang R, Wang J, Zhang A
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
Effects of Modified Xuanbai Chengqi Decoction against secondary Streptococcus pneumoniae infection following influenza virus infection: A multi-omics analysis.
Yang J, Shi J, Xu W, Mu J, Chang Y, Zhang X, Wang X
Journal of ethnopharmacology 2026 Jan 10;354:120458
Journal of ethnopharmacology 2026 Jan 10;354:120458
Combined metabolomics and gut microbiota analysis reveals the protective effects of α-monoglucosyl rutin against cyclophosphamide-induced intestinal injury.
Tian J, Xiao F, Xu Y, Chen Y, He C, Jiang S, Tang Y
International immunopharmacology 2026 Jan 1;168(Pt 2):115887
International immunopharmacology 2026 Jan 1;168(Pt 2):115887
Lycium barbarum polysaccharide LBP3 alleviates 5-Fluorouracil-induced intestinal injury via a mechanism associated with activating Nrf2 and improving mitochondrial function.
Xie X, Cai Y, Xu R, Yang C, Li P, Zhu Y, Luo X, Zhou L, Wang Q
International immunopharmacology 2026 Jan 1;168(Pt 2):115879
International immunopharmacology 2026 Jan 1;168(Pt 2):115879
Differentiating Damp-Heat and Cold-Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short-Chain Fatty Acid Profiling.
Zhang H, Song X, Mi W, Ji P, Wei Y, Hua Y
MicrobiologyOpen 2026 Feb;15(1):e70164
MicrobiologyOpen 2026 Feb;15(1):e70164
Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing.
Zhang Y, Tu S, Shao X, Meng J, Zhang Z, Wei W, Jing X, Qin Z, Wu J, Xu W, Dong B, Gao J, Qu A, Chen S, Zhang L, Gong P, Shan B, Shi H, Zhu SJ
Nature communications 2026 Feb 6;17(1)
Nature communications 2026 Feb 6;17(1)
A microbiota-IPA axis facilitates intestinal stem cell-mediated regeneration in colitis through a Hopx-associated program.
Zhang Y, Meng J, Tu S, Ma L, Zhao X, Gao J, Wu J, Xu W, Chen S, Cheng H, Zhang L, Zhu SJ
Nature communications 2026 Feb 25;17(1)
Nature communications 2026 Feb 25;17(1)
CD177(+) neutrophils alleviate acute pancreatitis-associated lung injury by protecting colonic barrier and restoring gut microbiota.
Ji L, Chen Y, Gong L, Li J, Xiong Y, Zhao Y, Li Y, Han Z, Yang Z, Jiang Q, Wu D
Cellular and molecular life sciences : CMLS 2026 Feb 18;83(1)
Cellular and molecular life sciences : CMLS 2026 Feb 18;83(1)
Development and characterization of immortalized mouse intestinal epithelial cell lines.
Zhou JY, Espenschied ST, Lu Q, Karell PE, Lewis KJ, Newhall KP, Han Y, Bambroo M, Job A, Stappenbeck TS
Scientific reports 2026 Feb 11;16(1)
Scientific reports 2026 Feb 11;16(1)
Jiawei Danxuan Koukang and Its Component Kaempferol Alleviate Oral Submucous Fibrosis by Restoring Epithelial-Fibroblast Homeostasis and Suppressing Neutrophil Recruitment via the ANXA1/FPR2 Axis.
Xiao Y, Tan Y, Liu Y, Chen R, Zhou T, Hu Z, Tan J
Food science & nutrition 2026 Apr;14(4):e71785
Food science & nutrition 2026 Apr;14(4):e71785
Puerarin Alleviates Depression via Integrated Regulation of TLR4/MyD88/NF-κB Signaling and Gut Microbiota-Metabolic Axis.
Cao XY, Tian JJ, Zhang W, Chen CL, Ma H
Neurochemical research 2026 Apr 10;51(2)
Neurochemical research 2026 Apr 10;51(2)
Polydisperse polystyrene microplastics exacerbate colitis through gut microbiota-butyrate-PPARγ axis disruption in mice.
Zhai Z, Yang Y, Xu Y, Fu Q, Chen S, Wu Z
Journal of hazardous materials 2026 Apr 1;507:141722
Journal of hazardous materials 2026 Apr 1;507:141722
Canine-derived Weissella confusa ZJUIDS-D034 and Enterococcus faecalis ZJUIDS-D016 combat aging by regulating gut microbiota.
Chen N, Yu Z, Ji X, Zhang S, Yu C, Valencak TG, Shi F, Ren D
Current research in microbial sciences 2025;8:100381
Current research in microbial sciences 2025;8:100381
The role of the gut microbiota and the nicotinate/nicotinamide pathway in rotenone-induced neurotoxicity.
Sai Y, Ge W, Zhong L, Zhang Q, Xiao J, Shan Y, Ye W, Liu H, Liu S, Ye F, Wang X, Tang H, Zhao Y, Dan G
Current research in toxicology 2025;8:100212
Current research in toxicology 2025;8:100212
A Hepatic Oxidative Metabolite of Palmatine Ameliorates DSS-Induced Ulcerative Colitis by Regulating Macrophage Polarization Through AMPK/NF-κB Pathway.
Huang QT, Ma XD, Zhang JN, Lin WX, Shen XX, Huang ZW, Zhang X, Wu XY, Dou YX, Su ZR, Su JY, Li YC, Liu YH, Xie YL, Lin RF, Huang HY, Zhang QH, Huang XQ
The American journal of Chinese medicine 2025;53(1):285-307
The American journal of Chinese medicine 2025;53(1):285-307
Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway.
Wang T, Ou Y, Xiong W, Luo L, Xu Y, Chen G, Peng Y, Chen Y, Zeng H, Yu Y, Tang H, Yao H, Wang W
Journal of inflammation research 2025;18:7301-7321
Journal of inflammation research 2025;18:7301-7321
Fingolimod Suppresses NLRP3 Inflammasome Activation and Alleviates Oxidative Stress in Traumatic Brain Injury-Induced Acute Lung Injury.
Shi Q, Hu T, Xu L, Fu J, Fang Y, Lan Y, Fan W, Wu Q, Tong X, Yan H
Journal of inflammation research 2025;18:2229-2245
Journal of inflammation research 2025;18:2229-2245
Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin.
Bai Q, Zhao Z, Duan Y, Cai R, Chen Y, Zhou C, Tian X, Yang Y, Wu H, Li M, You J, Song Q, Dong H, Liu T
Frontiers in microbiology 2025;16:1594012
Frontiers in microbiology 2025;16:1594012
Aqueous extracts of Elsholtzia ciliata and Hovenia dulcis ameliorate loperamide-induced constipation in mice by promoting intestinal peristalsis and barrier function and the abundance of intestinal beneficial bacteria.
Wu J, Xin Q, Wang S, Zhang X, Jiang C
Frontiers in microbiology 2025;16:1531232
Frontiers in microbiology 2025;16:1531232
Porphyromonas gingivalis-induced periodontitis promotes neuroinflammation and neuronal loss associated with dysfunction of the brain barrier.
Jiang Y, Xu L, Zhao X, Shen H, Qiu C, He Z, Song Z, Zhou W
Frontiers in cellular and infection microbiology 2025;15:1559182
Frontiers in cellular and infection microbiology 2025;15:1559182
Association between AHR in EGCs and IBS-D patients: the indole pathway of tryptophan metabolism.
Wang L, Zhang Y, Ran Y, Li L, Mei L, Ye F, Sun Y, Wang T, Quan X, Shi H, Dai F
Frontiers in nutrition 2025;12:1566595
Frontiers in nutrition 2025;12:1566595
Stachyose alleviates high-fat diet-induced obesity via browning of white adipose tissue and modulation of gut microbiota.
Chen S, Li T, Zhao P, Liang P, Huang X, Song L, Wang T
Current research in food science 2025;10:101081
Current research in food science 2025;10:101081
Sulfation and carboxymethylation of Citrus medica 'Fingered' polysaccharides: Physicochemical properties and protective effects against LPS-induced intestinal barrier injury in Caco-2 cells.
Xiong F, Yao HL, Wu YH, Hu WH, Ou YH, Li HJ, Lan WJ
International journal of biological macromolecules 2025 Sep;321(Pt 1):146211
International journal of biological macromolecules 2025 Sep;321(Pt 1):146211
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD.
Xue W, Fan X, Hui Y, Yu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115570
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115570
Lycopene ameliorates Di-(2-ethylhexyl) phthalate-induced neurotoxicity in mice via the gut-brain axis.
Chen LJ, Liu Y, Liu JL, Chen ZJ, Zhao W, Li JH, Hsu C, Chen L, Zeng JH, Li XW, Yang JZ, Li JH, Xie XL, Tao SH, Wang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157057
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157057
HDAC/NF-κB signaling pathway mediates gut microbiota dysbiosis in rheumatoid arthritis: Intervention mechanisms of Fengshining decoction.
Wen Y, Li M, Hao Y, Peng J, Wei X, Zhang Z, Liu B, Wang Y, Peng T, Ma Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156976
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156976
Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia-Reperfusion Injury.
Jin H, Li Z, Tan S, Xiao Q, Li Q, Ye J, Zhou Y, Wan Y, Liu Q, Menon BK, Hu B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03722
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03722
Lithocholic acid ameliorates ulcerative colitis via the PXR/TLR4/NF-κB/NLRP3 signaling pathway and gut microbiota modulation.
Liu Y, Gao J, Chen L, Chen Y, Jiang J, Chen H, Ma L
Cellular and molecular life sciences : CMLS 2025 Sep 4;82(1):336
Cellular and molecular life sciences : CMLS 2025 Sep 4;82(1):336
Palmatine ameliorates intestinal epithelial barrier injury in ulcerative colitis via targeting enolase 3.
Zhang Y, Lai Z, Hu X, Wu M, Chen S, Su L, Xie S, Ren M, Yang B, Wang J, Huang W, Su Z, Li Z, Xie Y
International immunopharmacology 2025 Sep 23;162:115110
International immunopharmacology 2025 Sep 23;162:115110
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/NF-κB/MLCK/MLC signaling in ulcerative colitis.
Zhou R, Cui Y, Wang W, Qu Y, Zhang G, Wang X, Sun Y, Li J
International immunopharmacology 2025 Sep 23;162:115099
International immunopharmacology 2025 Sep 23;162:115099
Electroacupuncture suppresses motor impairments via microbiota-metabolized LPS/NLRP3 signaling in 6-OHDA induced Parkinson's disease rats.
Quan J, Liu X, Liang S, Nie L, Zhang L, Hong X, He M, Lei S, Duan L, Zhang Y, Zhuang L
International immunopharmacology 2025 Sep 23;162:115089
International immunopharmacology 2025 Sep 23;162:115089
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression.
He Z, Feng YD, Zhang YX, Gao X, Liu JJ, Liu S, Wu GQ
Cellular signalling 2025 Oct;134:111932
Cellular signalling 2025 Oct;134:111932
Neuronal pentraxin 1 accelerates post-stroke atherosclerosis by inducing endothelial cell senescence.
Wu Y, Luo R, Guan H, Zhang X, Yang X, Wang W, Li Q
International immunopharmacology 2025 Oct 30;164:115363
International immunopharmacology 2025 Oct 30;164:115363
OSBPL2 deficiency impaired cochlear blood-labyrinth barrier via activation of NF-κB signaling pathway.
Yang Q, Li T, Lu Y, Wang T, Chen Z, Xing G, Wei Q, Cao X, Yao J
Hearing research 2025 Nov;467:109432
Hearing research 2025 Nov;467:109432
Basic Fibroblast Growth Factor-Releasing Bioabsorbable Polyglycolic Acid Dura Mater Enhances Neural Progenitor Cell Proliferation and Neuroprotection After Brain Injury.
Ito Y, Oyane A, Matsumaru Y, Ishikawa E
Brain and behavior 2025 Nov;15(11):e71008
Brain and behavior 2025 Nov;15(11):e71008
Traditional wisdom meets modern science: The protective role of sanhuang shu'ai decoction in ulcerative colitis models.
Zhang N, Liu A, Cao M, Han Z, Guo D, Zhang S, Zhang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157163
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157163
Xinqingning tablet attenuates ischemic stroke complicated by gut dysbiosis through regulating the miR-126-driven gut-brain axis.
Gong S, Xu Y, Zhao R, Yu J, Bao L, Zhang Y, Li F, Jiao L, Kou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157356
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157356
Aglycin ameliorates nonalcoholic fatty liver disease through modulation of the gut microbiota, restoration of the intestinal barrier, and inhibition of hepatic inflammation in mice.
Zhou L, Li J, Wei W, Ma X, Xu Z, Ouyang L, Guan Y, Jia X, Wu Q, Zhao M
Food & function 2025 Nov 24;16(23):9191-9207
Food & function 2025 Nov 24;16(23):9191-9207
Effects of fasudil against photothrombotic stroke in genetically modified obese (ob/ob) mice.
Salman M, Shahzad H, Bhattacharya SK, Gangaraju R, Brown CM, Ishrat T
Metabolic brain disease 2025 Nov 15;40(8):315
Metabolic brain disease 2025 Nov 15;40(8):315
Gut Microbiota and Bile Acid Metabolism in the Mechanism of Ginsenoside Re Against Nonalcoholic Fatty Liver Disease.
Zheng Y, Chen J, Zhang Y, Guan H, Deng S, Chang D, Wang Y, Lu J, Zhou X, Xie Q, Song J, Huang M
Phytotherapy research : PTR 2025 May;39(5):2339-2356
Phytotherapy research : PTR 2025 May;39(5):2339-2356
Protective effects of jiawei yupingfeng polysaccharides on cyclophosphamide-induced intestinal injury in mice.
Wu R, Zhao N, Li H, Zhang W, Hua Y, Ji P, Wei Y
International journal of biological macromolecules 2025 May;310(Pt 3):143405
International journal of biological macromolecules 2025 May;310(Pt 3):143405
Larimichthys crocea isinglass polysaccharide attenuates DSS-induced colitis via gut microbiota regulation and NF-κB signaling inhibition.
Sui D, Li M, Ai C, Li S, Chang H, Li Y, Zhao S, Li H, Ren X
International journal of biological macromolecules 2025 May;307(Pt 3):142263
International journal of biological macromolecules 2025 May;307(Pt 3):142263
Proline rich-39 (PR-39) antimicrobial protein alleviated lipopolysaccharide-induced intestinal barrier dysfunction in piglets by altering intestinal flora associated bile acid metabolism and in turn regulating TGR-5/NF-κB/MLCK/MLC pathway.
Liu Z, Qin X, Zhang B, Nong K, Chen W, Yang Z, Lang W, Liu X, Li L, Wang X, Shi H, Zhang H
International journal of biological macromolecules 2025 May;307(Pt 1):141930
International journal of biological macromolecules 2025 May;307(Pt 1):141930
Puerarin improves MASLD by remodeling intestinal microenvironment to promote mitochondrial fusion and autophagy.
Sun C, Du M, Sha S, Wang S, Li L, Hou J, Li L, Yuan J, Yan J, Yang Z
Journal of pharmacological sciences 2025 May;158(1):27-41
Journal of pharmacological sciences 2025 May;158(1):27-41
Three-Dimensional Dynamic Blood-Brain Barrier Model Incorporating Native Cell Culture Systems Based on Shape Memory Biomaterials.
Ta W, Wang J, Zheng A, Jia Y, Liu J, Lu W, Zhang J
Advanced healthcare materials 2025 May;14(12):e2500066
Advanced healthcare materials 2025 May;14(12):e2500066
Network-based pharmacological and experimentally validated study on the therapeutic effects and mechanisms of Polygonatum Rhizoma Ginseng Formula in immunocompromised mice.
He X, Xu W, Li L, Jiang X, Dong Y, Liu K, Feng X, Su J, Li B, Lv G, Chen S
Journal of ethnopharmacology 2025 May 28;348:119821
Journal of ethnopharmacology 2025 May 28;348:119821
Enhanced alleviation of the selenite-grafted soluble and nondigestive Chinese Yam polysaccharides on nonylphenol-induced cytotoxicity and barrier damage in intestinal epithelial cells.
Wang ZX, Zhang LL, Zhao XH
Scientific reports 2025 May 23;15(1):17970
Scientific reports 2025 May 23;15(1):17970
Probiotics may not adhere to gut and provide benefits in inflammatory bowel disease patients based on an AOM/DSS murine model.
Hu ML, Wang FS, Lian WS, Yang CH, Yang JW, Chen IY, Huang CH, Liou JS, Yang MY
Journal of the Formosan Medical Association = Taiwan yi zhi 2025 May 19;
Journal of the Formosan Medical Association = Taiwan yi zhi 2025 May 19;
Multiomics analysis revealed the effects of polystyrene nanoplastics at different environmentally relevant concentrations on intestinal homeostasis.
Yang JZ, Li JH, Liu JL, Zhou AD, Wang H, Xie XL, Zhang KK, Wang Q
Environmental pollution (Barking, Essex : 1987) 2025 May 1;372:126050
Environmental pollution (Barking, Essex : 1987) 2025 May 1;372:126050
A derivative of tanshinone IIA and salviadione, 15a, inhibits inflammation and alleviates DSS-induced colitis in mice by direct binding and inhibition of RIPK2.
Hu CH, Chen Y, Jin TY, Wang Z, Jin B, Liao J, Ding CY, Zhang A, Tang WY, Zhang LX, Xu LY, Ning FM, Liang G, Wei XH, Wang Y
Acta pharmacologica Sinica 2025 Mar;46(3):672-686
Acta pharmacologica Sinica 2025 Mar;46(3):672-686
Exploring the Role of Gut Vascular Barrier Proteins in HIV-Induced Mucosal Damage: A Comparative Study.
Jin L, Hu R, Qing Y, Rang Z, Cui F
AIDS research and human retroviruses 2025 Mar;41(3):159-166
AIDS research and human retroviruses 2025 Mar;41(3):159-166
The impact of combined thymol and rosmarinic acid on the intestinal microbiota and barrier function of the piglets challenged by Escherichia coli K88.
Li R, Ding X, Lei M, Li P, Giannenas I, Wang J, Zhu W
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Mar;20:131-144
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Mar;20:131-144
Polydatin, a derivative of resveratrol, ameliorates busulfan-induced oligozoospermia in mice by inhibiting NF-κB pathway activation and suppressing ferroptosis.
Wang C, Li X, Ye T, Gu J, Zheng Z, Chen G, Dong J, Zhou W, Shi J, Zhang L
Bioorganic chemistry 2025 Mar;156:108170
Bioorganic chemistry 2025 Mar;156:108170
PIWI-interacting RNA MIABEPIR regulates cerebral endothelial cell function via DAPK2 pathway in offspring following maternal immune activation.
Li SS, Guo M, Long Y, Cai Y, Zhao Y, Huang S, Yang H, Fan Y, Chen X, Jin X
Clinical and translational medicine 2025 Mar;15(3):e70260
Clinical and translational medicine 2025 Mar;15(3):e70260
L-Arabinose Alleviates Functional Constipation in Mice by Regulating Gut Microbiota and Metabolites.
Liu K, Dong H, Li X, Hu C, Cui F, Li S, Zhang X, Du Y, Yang P, Ji W, Sui W, Meng J
Foods (Basel, Switzerland) 2025 Mar 6;14(5)
Foods (Basel, Switzerland) 2025 Mar 6;14(5)
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Hao Z, Ji R, Su Y, Wang H, Yang W, Zhang S, Liu Y, Ma S, Guan F, Cui Y
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Antihypertensive effects of rice peptides involve intestinal microbiome alterations and intestinal inflammation alleviation in spontaneously hypertensive rats.
Li J, Wei W, Ma X, Ji J, Ling X, Xu Z, Guan Y, Zhou L, Wu Q, Huang W, Liu F, Zhao M
Food & function 2025 Mar 3;16(5):1731-1759
Food & function 2025 Mar 3;16(5):1731-1759
Gancao Xiexin decoction attenuated experimental colitis through suppressing ACSL4-mediated ferroptosis.
Pan Z, Gan C, Zhi S, Yang Y, Zhang Y, Li L, Zhang S, Huang Q
Journal of ethnopharmacology 2025 Mar 26;344:119532
Journal of ethnopharmacology 2025 Mar 26;344:119532
Intranasal Delivery of Hydrophobic AC5216 Loaded Nanoemulsion into Brain To Alleviate Chronic Unpredictable Stress-Induced Depressive-like Behaviors.
Zhang Y, Wang Y, Wang H, Bian L, Gao F, Yao H, Xie J
ACS applied materials & interfaces 2025 Mar 19;17(11):16533-16547
ACS applied materials & interfaces 2025 Mar 19;17(11):16533-16547
VopX, a novel Vibrio cholerae T3SS effector, modulates host actin dynamics.
Ulbrich M, Seward CH, Ivanov AI, Ward BM, Butler JS, Dziejman M
mBio 2025 Mar 12;16(3):e0301824
mBio 2025 Mar 12;16(3):e0301824
Taurine ameliorates deoxynivalenol-induced intestinal injury in piglets: Restoration of mitochondrial function linked to the PGC1α-NRF1/2 axis.
Ji X, Ding H, Zhou F, Zhang F, Wu D
Ecotoxicology and environmental safety 2025 Mar 1;292:117938
Ecotoxicology and environmental safety 2025 Mar 1;292:117938
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
Wang T, Chen J, Shu C, Shen X, Fu Y, Li M, Luo Z
Acta biomaterialia 2025 Mar 1;194:396-410
Acta biomaterialia 2025 Mar 1;194:396-410
Milk Exosomes From Gestational Diabetes Mellitus Parturients Demonstrate Weaker Ability to Promote Intestinal Development in Offspring.
Mo J, Ding Y, Yang J, Zheng Z, Lu J, Luo H, Wang J, Lin F, Chen J, Li Q, Zheng X, Zha L
Molecular nutrition & food research 2025 Jun;69(11):e70026
Molecular nutrition & food research 2025 Jun;69(11):e70026
Blockade of A(2A)R improved brain perfusion and cognitive function in a mouse model of Alzheimer's disease.
Udo MSB, Zaccarelli-Magalhães J, Clemons GA, Citadin CT, Langman J, Smith DJ, Matuguma LH, Tesic V, Lin HW
GeroScience 2025 Jun;47(3):4153-4167
GeroScience 2025 Jun;47(3):4153-4167
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
He W, Wang X, Zhang J, Cao H, Ren S, Sun X, Yu H, Zhang G, Li C, Liu L, Wang C, He J
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Scutellaria baicalensis Extracts Restrict Intestinal Epithelial Cell Ferroptosis by Regulating Lipid Peroxidation and GPX4/ACSL4 in Colitis.
Zhang J, Tan B, Wu H, Han T, Fang D, Cai H, Hu B, Kang A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156708
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156708
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Deng B, Wang K, He H, Xu M, Li J, He P, Liu Y, Ma J, Zhang J, Dong W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Rag1(-/-) mice with T and B lymphocyte deficiency exhibit milder retinal inflammatory response and retinal ganglion cell injury after optic nerve crush.
Cheng Y, Lin D, Wu S, Yan X, Liu Q, Wang N, Zhang J
Neuroscience 2025 Jun 7;576:129-137
Neuroscience 2025 Jun 7;576:129-137
Sesamin improved growth and overall health in young animals by enhancing gut-liver axis function.
Chen C, Qi M, Xu Z, Wen J, Tang W, Diao H, Li Z, Chu Y, Feng F, Tang Z
Food & function 2025 Jun 3;16(11):4415-4436
Food & function 2025 Jun 3;16(11):4415-4436
Flos lonicerae polysaccharide alleviates inflammatory bowel disease by improving intestinal microbiota and inhibiting oxidative stress and the NF-κB pathway.
Xia Y, Zhou X, Cai P, Yan R, Ocansey DKW, Mao F
International immunopharmacology 2025 Jun 26;159:114956
International immunopharmacology 2025 Jun 26;159:114956
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
Zheng X, Cao Z, Wang M, Yuan R, Han Y, Li A, Wang X
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Liang H, Liang Y, Wu L, Lin L, Yao Y, Deng J, Xu J, Li H, Gao F, Xing W, Yu M, Jia X, Wei M, Li C, Zheng G
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
From TCM "Shen-nourishing" and "Yang-strengthening" theory to blood-testis barrier reorganization, GuiLuBuShen attenuates age-related male reproductive dysfunction.
Jia D, Chen DX, Guo QP, Ou HY, Liu B, Dai WP, Peng ZL, Liu YJ, Wang QP, Tan QY, Chen W, Liu JY
Journal of ethnopharmacology 2025 Jun 12;349:119899
Journal of ethnopharmacology 2025 Jun 12;349:119899
Integrating transcriptomics, metabolomics, and microbiomics to explore the mechanism of action of bran-fried Atractylodes lancea rhizome polysaccharide in ameliorating the enhanced pharmacological effects of dextran sodium sulfate-induced colitis.
Yao D, Ma C, Ke C, Wang D, Xu K, Liu Y, Qu L
Journal of ethnopharmacology 2025 Jun 12;349:119805
Journal of ethnopharmacology 2025 Jun 12;349:119805
Echinacoside alleviates type 2 diabetes mellitus through inhibiting hepatic gluconeogenesis via gut bacterial-fungal trans-kingdom network reconstruction.
Fan L, Liu J, Li L, Yang X, Zhao Q, Zhao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156802
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156802
Music intervention mitigates LPS-induced gut barrier disruption and immune stress in broilers via TLR4/NF-κB regulation.
Jin S, Wang H, Gong H, Guo L, Zhang H, Zhang J, Chang Q, Li J, Zhang R, Bao J
Poultry science 2025 Jul;104(7):105189
Poultry science 2025 Jul;104(7):105189
ShenQiGan Extract Repairs Intestinal Barrier in Weaning-Stressed Piglets by Modulating Inflammatory Factors, Immunoglobulins, and Short-Chain Fatty Acids.
Guo R, Jiang C, Niu Y, Niu C, Chen B, Yuan Z, Hua Y, Wei Y
Animals : an open access journal from MDPI 2025 Jul 28;15(15)
Animals : an open access journal from MDPI 2025 Jul 28;15(15)
The promoting effect of high-fat diet-induced trained immunity on ulcerative colitis and the mechanism of the therapeutic effect of Dahuang Mudan Decoction.
Li P, Xu R, Chen H, Cao S, Xie X, Xu B, Chen Y, Xie X, Yang C, Wang Q, Luo X, Zhou L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156893
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156893
Nuciferine ameliorates blood-brain barrier disruption post-ischemic stroke via inhibiting the JAK2/STAT3 pathway.
Li J, Liu M, Fan M, Tian Q, Wang J, Du Y, Yu J, Li X, Yang L, Zhao M, Gao Y, Sun T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156829
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156829
Exploring the Mechanism of Kidney Injury in Mice Induced by High-Fat Diet and Polystyrene Nanoplastics Co-Exposure Through the Kidney-Gut Axis.
Dong J, Yang F, Xu Y, Zhao Q, Li X, Liu T, Tang Y
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17956-17966
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17956-17966
Kushenol I combats ulcerative colitis via intestinal barrier preservation and gut microbiota optimization.
He XD, Li M, Zuo XD, Ni HY, Han YX, Hu YK, Yu J, Yang XX
World journal of gastroenterology 2025 Jul 14;31(26):105656
World journal of gastroenterology 2025 Jul 14;31(26):105656
Maternal lead exposure impairs offspring growth and intestinal microbiota via AMPK/ULK1 pathway activation.
He Y, Wang M, An M, Kulyar MF, Li M, Xu H, Wang Y
Ecotoxicology and environmental safety 2025 Jul 1;299:118345
Ecotoxicology and environmental safety 2025 Jul 1;299:118345
Hyperoside promotes autophagy of colonic epithelial cells to protect intestinal barrier function in ulcerative colitis.
Xia W, Lin H, Zhang J, Bai Y, Wei Z, Zhao H, Xia Y, Dai Y
Food & function 2025 Jul 1;16(13):5543-5555
Food & function 2025 Jul 1;16(13):5543-5555
Wolfberry Honey and Its Extract Alleviate Dextran Sodium Sulfate-Induced Ulcerative Colitis by Improving Intestinal Barrier Function and Reducing Oxidative Stress and Inflammation.
Yuan J, Wu Q, Guo Y, Tang Y, Gao S, Li T, Xuan H
Molecular nutrition & food research 2025 Jan;69(2):e202400726
Molecular nutrition & food research 2025 Jan;69(2):e202400726
Chronic arsenic exposure-provoked biotoxicity involved in liver-microbiota-gut axis disruption in chickens based on multi-omics technologies.
Li J, Guo C, Liu Y, Han B, Lv Z, Jiang H, Li S, Zhang Z
Journal of advanced research 2025 Jan;67:373-386
Journal of advanced research 2025 Jan;67:373-386
Discovery of a novel AhR-CYP1A1 axis activator for mitigating inflammatory diseases using an in situ functional imaging assay.
Zhang F, Zhao B, Fan Y, Qin L, Shi J, Chen L, Xu L, Jin X, Sun M, Deng H, Zeng H, Xiao Z, Yang X, Ge G
Acta pharmaceutica Sinica. B 2025 Jan;15(1):508-525
Acta pharmaceutica Sinica. B 2025 Jan;15(1):508-525
Ubiquitin-specific protease 25 ameliorates ulcerative colitis by regulating the degradation of phosphor-STAT3.
Liu Z, Liu J, Wei Y, Li J, Zhang J, Yu R, Yang Q, Miao Y, Dong W
Cell death & disease 2025 Jan 7;16(1):5
Cell death & disease 2025 Jan 7;16(1):5
Mechanistic study of the effect of a high-salt diet on the intestinal barrier.
Chen L, Tang J, Xia Y, Wang J, Xia LN
Scientific reports 2025 Jan 30;15(1):3826
Scientific reports 2025 Jan 30;15(1):3826
Interleukin 8 exacerbates age-related hearing loss through regulating perivascular-resident macrophage-like melanocytes viability and the permeability of the endothelial cells.
Chen S, Zhou Y, Wu J, Lin J, Hong Z, Wang Y, Han Y, Luo X
International immunopharmacology 2025 Jan 27;146:113820
International immunopharmacology 2025 Jan 27;146:113820
Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners.
Qin X, Shi H, Li H, Chu B, Zhang J, Wen Z, Sun X, Wang H, He Y
Nature communications 2025 Jan 2;16(1):33
Nature communications 2025 Jan 2;16(1):33
Multi-omics analysis and experimental verification reveal testicular fatty acid metabolism disorder in non-obstructive azoospermia.
Li Z, Xiang YJ, Zou ZC, Feng YM, Wang H, Chen WQ, Ge X, Ma JZ, Jing J, Yao B
Zoological research 2025 Jan 18;46(1):177-192
Zoological research 2025 Jan 18;46(1):177-192
Neohesperidin Mitigates High-Fat-Diet-Induced Colitis In Vivo by Modulating Gut Microbiota and Enhancing SCFAs Synthesis.
Lu K, Shan S, Zeng Y, Yang G
International journal of molecular sciences 2025 Jan 10;26(2)
International journal of molecular sciences 2025 Jan 10;26(2)
Discovery of anti-inflammatory molecules from Dendrobium officinale based on activity labelled molecular networking and its alleviation effect on ulcerative colitis.
Dai J, Wang W, He F, Yu X, Liu Z, Wang Y, Zou D
Food research international (Ottawa, Ont.) 2025 Feb;203:115888
Food research international (Ottawa, Ont.) 2025 Feb;203:115888
Xylooligosaccharide and Akkermansia muciniphila synergistically ameliorate insulin resistance by reshaping gut microbiota, improving intestinal barrier and regulating NKG2D/NKG2DL signaling in gestational diabetes mellitus mice.
Wang J, Wu Y, Yang J, Ying S, Luo H, Zha L, Li Q
Food research international (Ottawa, Ont.) 2025 Feb;201:115634
Food research international (Ottawa, Ont.) 2025 Feb;201:115634
Stigmasterol from Prunella vulgaris L. Alleviates LPS-induced mammary gland injury by inhibiting inflammation and ferroptosis.
Sun M, Xu D, Liu D, Ran X, Li F, Wang J, Ge Y, Liu Y, Guo W, Liu J, Cao Y, Fu S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156362
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156362
Porphyromonas gingivalis and Its Outer Membrane Vesicles Induce Neuroinflammation in Mice Through Distinct Mechanisms.
Qiu Y, Zhao Y, He G, Yang D
Immunity, inflammation and disease 2025 Feb;13(2):e70135
Immunity, inflammation and disease 2025 Feb;13(2):e70135
Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway.
Li T, Hu G, Fu S, Qin D, Song Z
Microbiology spectrum 2025 Feb 4;13(2):e0200624
Microbiology spectrum 2025 Feb 4;13(2):e0200624
House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK/AP-1/IL-24 Signaling pathway in allergic rhinitis.
Zhang S, Wu W, Gu M, Zhao Y, Wang L, Liu K, Yu Z
International immunopharmacology 2025 Feb 20;148:113972
International immunopharmacology 2025 Feb 20;148:113972
Treatment of Acute Ulcerative Colitis with Zinc Hyaluronate in Mice.
Zhang L, Fu X, Li J, Xiao W, Xiong X, Lv H, Zhang Z, Ju J
Journal of microbiology and biotechnology 2025 Feb 14;35:e2408050
Journal of microbiology and biotechnology 2025 Feb 14;35:e2408050
Bisdemethoxycurcumin and Curcumin Alleviate Inflammatory Bowel Disease by Maintaining Intestinal Epithelial Integrity and Regulating Gut Microbiota in Mice.
Hsu KY, Majeed A, Ho CT, Pan MH
Journal of agricultural and food chemistry 2025 Feb 12;73(6):3494-3506
Journal of agricultural and food chemistry 2025 Feb 12;73(6):3494-3506
Polysaccharides from Lycium barbarum, yam, and sunflower ameliorate colitis in a structure and intrinsic flora-dependent manner.
Zhang S, Zhou R, Xie X, Xiong S, Li L, Li Y
Carbohydrate polymers 2025 Feb 1;349(Pt A):122905
Carbohydrate polymers 2025 Feb 1;349(Pt A):122905
Dietary baking soda (NaHCO(3)) therapy recovered urolithiasis-induced kidney injury in mice by inhibition of oxidative stress, pyroptosis, and inflammation through gut-kidney axis.
Liu S, Gao Y, Luo J, Chen Y, Cao H, Guo Z, Zhou H, Hong Z, Chen B, Xu X, Zhang J, Duan N, Zhan X, Yao X, Xie T, Dong Y, Xu Y
Renal failure 2025 Dec;47(1):2521456
Renal failure 2025 Dec;47(1):2521456
The T-type voltage-gated Ca(2+) channel Ca(V)3.1 involves in the disruption of respiratory epithelial barrier induced by Pasteurella multocida toxin.
Bi H, Wang F, Lin L, Zhang D, Chen M, Shang Y, Hua L, Chen H, Wu B, Peng Z
Virulence 2025 Dec;16(1):2466482
Virulence 2025 Dec;16(1):2466482
The Protective Efficacy of Total Alkaloids from Nelumbinis Plumula on Irradiation-Induced Oxidative Stress Damage in Human Umbilical Vein Endothelial Cells.
Bu J, Xia Z, Zhang J, Yan L, Luo Y, Zhang Z, Li M, Liu S, Tian Y
Antioxidants (Basel, Switzerland) 2025 Dec 30;15(1)
Antioxidants (Basel, Switzerland) 2025 Dec 30;15(1)
A novel long-galanin peptide from non-mammalian vertebrates mitigates the inflammatory response in IBD models via the biased GALR2/β-arrestin2 pathway.
Lai S, Kong X, Xue J, Ma K, Amanullah A, Chen Y, Yang N, Zhang T, Zheng K, Zeng T, Yan X, Zhang C, Kamal S, Ullah N, Luo C, Brosius J, Deng C
Nature communications 2025 Dec 13;16(1):11512
Nature communications 2025 Dec 13;16(1):11512
Embryonic exposure to GenX causes reproductive toxicity by disrupting the formation of the blood-testis barrier in mouse offspring.
Fan Z, Hong R, Li S, Kong L, Zhou Q, Ma T, Chen H, Pan C
Toxicology 2025 Aug;515:154161
Toxicology 2025 Aug;515:154161
Pristimerin Alleviates DSS-Induced Colitis in Mice by Modulating Intestinal Barrier Function, Gut Microbiota Balance and Host Metabolism.
Wang Y, Qin X, Shuai J, Wan X, Yu D, Ling L, Lu Q, Lv M
Inflammation 2025 Aug;48(4):2166-2181
Inflammation 2025 Aug;48(4):2166-2181
Akkermansia muciniphila Akk11 Supplementation Attenuates MPTP-Induced Neurodegeneration by Inhibiting Microglial NLRP3 Inflammasome.
Wang W, Shi S, Su M, Li Y, Yao X, Jiang J, Yao W, Qin X, Wang Z, Tang C
Probiotics and antimicrobial proteins 2025 Aug;17(4):2348-2361
Probiotics and antimicrobial proteins 2025 Aug;17(4):2348-2361
Targeting CD38 to alleviate brain endothelial cell dysfunction and cognitive impairment in vascular dementia.
Yu M, Qi Z, Zhang J, Zhang Z, Chen J, Yan T, Chen Z
Journal of pharmacological sciences 2025 Aug;158(4):310-321
Journal of pharmacological sciences 2025 Aug;158(4):310-321
Apigenin mitigates intestinal barrier dysfunction in sepsis by modulating the AKT signaling pathway.
Lijun Z, Liping W, Dandan Z, Wenjie Z, Renjie X, Xueyan J, Wenqing C, Chen L, Lu Z
BMC gastroenterology 2025 Aug 30;25(1):626
BMC gastroenterology 2025 Aug 30;25(1):626
Anti-Obesity Effects of Pea Peptides Modified by Steam Explosion on Obese Mice: Regulation of Gut Microbiota and Glucose Metabolism.
Tu J, Liu C, Zhang J, Li T, Zhu J, Wang Q, Wu R, Wang T
Foods (Basel, Switzerland) 2025 Aug 28;14(17)
Foods (Basel, Switzerland) 2025 Aug 28;14(17)
Liberation of galactose from lactose by gut microbial β-galactosidase prevents uterine bacterial infection.
Cai J, He Y, Qu L, Liu J, Xie X, Cao Y
The ISME journal 2025 Aug 20;
The ISME journal 2025 Aug 20;
Bifidobacterium species associated with breastfeeding alleviate neonatal hyperbilirubinaemia via the gut microbiota-α-linolenic and linoleic acid metabolism-enterohepatic circulation axis.
Lin C, Lin Y, Xiao R, Guo M, Zhang H, Chen W, Wang G
Microbiome 2025 Aug 19;13(1):187
Microbiome 2025 Aug 19;13(1):187
β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD(+)/SIRT1 signaling pathways.
Yang X, Zheng E, Lin Y, Sun H, Zhang J, Yu Y
Hereditas 2025 Aug 16;162(1):161
Hereditas 2025 Aug 16;162(1):161
Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome.
Zhang Y, Si L, Shu X, Qiu C, Wan X, Li H, Ma S, Jin X, Wei Z, Hu H
Microbiome 2025 Apr 7;13(1):93
Microbiome 2025 Apr 7;13(1):93
Podophyllotoxin Alleviates DSS-Induced Ulcerative Colitis via PI3K/AKT Pathway Activation.
Li T, Wang X, Wang J
Physiological research 2025 Apr 30;74(2):287-300
Physiological research 2025 Apr 30;74(2):287-300
Covalent Grafting of Inorganic Selenium to the Water-Soluble and Nondigestive Chinese Yam Polysaccharides Causes Greater Protection of IEC-6 Cells with Acrylamide Injury.
Wang ZX, Zhang LL, Zhao XH
Foods (Basel, Switzerland) 2025 Apr 29;14(9)
Foods (Basel, Switzerland) 2025 Apr 29;14(9)
Card9 deficiency exacerbates vulvovaginal candidiasis by impairing the IL-17 production and vaginal epithelial barrier.
Liu W, Song Y, Wang R, Wan Z, Li R, Wang X
Medical mycology 2025 Apr 2;63(4)
Medical mycology 2025 Apr 2;63(4)
HFD-induced LPS translocation and elevated blood lipids exacerbated the inflammatory response in allergic rhinitis.
Peng S, Cai X, Tang J, Huang J, Zhao X, Huang X, Li J
Scientific reports 2025 Apr 15;15(1):12931
Scientific reports 2025 Apr 15;15(1):12931
Total ginsenosides from wild ginseng improve immune regulation in a rat model of spleen qi deficiency by modulating fecal-bacteria-associated short-chain fatty acids and intestinal barrier integrity.
Bai R, Ma L, Li F, Pan L, Bao Y, Li X, Wang S, Yue H, Zheng F
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Apr 15;1256:124554
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Apr 15;1256:124554
Lactobacillus paracasei Expressing Porcine Trefoil Factor 3 and Epidermal Growth Factor: A Novel Approach for Superior Mucosal Repair.
Yin F, Chen Y, Zhang H, Zhao H, Li X, Wang Z, Meng W, Zhao J, Tang L, Li Y, Li J, Wang X
Veterinary sciences 2025 Apr 14;12(4)
Veterinary sciences 2025 Apr 14;12(4)
Exercise antagonizes cadmium-caused liver and intestinal injury in mice via Nrf2 and TLR2/NF-κB signalling pathway.
Zhang D, Liu J, Liu J, Fatima M, Yang L, Qin Y, Li W, Sun Z, Yang B
Ecotoxicology and environmental safety 2025 Apr 1;294:118100
Ecotoxicology and environmental safety 2025 Apr 1;294:118100
Cell Membrane-Coated Nanotherapeutics for the Targeted Treatment of Acute and Chronic Colitis.
Li S, Chen L, Wu T, Wu J, Yang H, Ju Q, Liu Z, Chen W, Zhang D, Hao Y
Biomaterials research 2024;28:0102
Biomaterials research 2024;28:0102
Therapeutic Effects of Lifei Decoction in a Murine Model of COPD Induced by LPS and Cigarette Smoke.
Lu L, Zhu C, Xu J, Hu Y, Dai J, Wang S, Wei T
International journal of chronic obstructive pulmonary disease 2024;19:957-967
International journal of chronic obstructive pulmonary disease 2024;19:957-967
Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB.
Zhou Y, Xiong X, Cheng Z, Chen Z, Wu S, Yu Y, Liu Y, Chen G, Li L
Drug design, development and therapy 2024;18:4825-4838
Drug design, development and therapy 2024;18:4825-4838
Fusobacterium Nucleatum Aggravates Intestinal Barrier Impairment and Colitis Through IL-8 Induced Neutrophil Chemotaxis by Activating Epithelial Cells.
Wang Z, Li B, Bao L, Chen Y, Yang J, Xu F, Shi S, Chen W, Wang B, Liu Y
Journal of inflammation research 2024;17:8407-8420
Journal of inflammation research 2024;17:8407-8420
Cistanche deserticola polysaccharide alleviates constipation by regulating intestinal barrier function and intestinal microbiota and their metabolites.
Yu Z, Zhang Z, Hu C, Xie L, Zhang R, Gao R, Zhang Z, Wei X, Li T, Guo J
American journal of translational research 2024;16(11):7036-7053
American journal of translational research 2024;16(11):7036-7053
Periplanta americana extract regulates the Th17/Treg cell balance via Notch1 in ulcerative colitis.
Zheng Y, Li H, Qi S, Xiao F, Song J, Liu S, Chen X, Li Y, Chen M
Frontiers in pharmacology 2024;15:1534772
Frontiers in pharmacology 2024;15:1534772
Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.
Zhu Y, Wang Y, Zuo X, Liu S, Cao L, Wang J, Yang Q, Huang Q, Huang Q, Tian M, Ping Y, Wu Q
Frontiers in immunology 2024;15:1525469
Frontiers in immunology 2024;15:1525469
Different effects of acute and chronic oxidative stress on the intestinal flora and gut-liver axis in weaned piglets.
Zhang H, Xiang X, Wang C, Li T, Xiao X, He L
Frontiers in microbiology 2024;15:1414486
Frontiers in microbiology 2024;15:1414486
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Wang Y, Bai Y, Cai Y, Zhang Y, Shen L, Xi W, Zhou Z, Xu L, Liu X, Han B, Yao H
Theranostics 2024;14(19):7292-7308
Theranostics 2024;14(19):7292-7308
Coactosin-like protein 1 regulates integrity and repair of model intestinal epithelial barriers via actin binding dependent and independent mechanisms.
Lechuga S, Marino-Melendez A, Davis A, Zalavadia A, Khan A, Longworth MS, Ivanov AI
Frontiers in cell and developmental biology 2024;12:1405454
Frontiers in cell and developmental biology 2024;12:1405454
Molecular hydrogen supplementation in mice ameliorates lipopolysaccharide-induced loss of interest.
Koga M, Sato M, Nakagawa R, Tokuno S, Asai F, Maezawa Y, Nagamine M, Yoshino A, Toda H
PCN reports : psychiatry and clinical neurosciences 2024 Sep;3(3):e70000
PCN reports : psychiatry and clinical neurosciences 2024 Sep;3(3):e70000
Lactobacillus gasseri ATCC33323 affects the intestinal mucosal barrier to ameliorate DSS-induced colitis through the NR1I3-mediated regulation of E-cadherin.
Qian G, Zang H, Tang J, Zhang H, Yu J, Jia H, Zhang X, Zhou J
PLoS pathogens 2024 Sep;20(9):e1012541
PLoS pathogens 2024 Sep;20(9):e1012541
Ningxiang pig-derived Enterococcus hirae HNAU0516 ameliorates postweaning diarrhoea by promoting intestinal health and modulating the gut microbiota in piglets.
Zhang LL, Wu ZC, Li JY, Li HK, Liu ZM, Wang J, Tan BE
Animal : an international journal of animal bioscience 2024 Sep;18(9):101220
Animal : an international journal of animal bioscience 2024 Sep;18(9):101220
Long-Term Exposure to Polystyrene Microspheres and High-Fat Diet-Induced Obesity in Mice: Evaluating a Role for Microbiota Dysbiosis.
Zhai Z, Yang Y, Chen S, Wu Z
Environmental health perspectives 2024 Sep;132(9):97002
Environmental health perspectives 2024 Sep;132(9):97002
Sanfeng Tongqiao Dripping Pills alleviate House Dust Mite-induced allergic rhinitis in mice by inhibiting Th2 differentiation and repairing the nasal epithelial barrier.
Lai M, Sun S, Zuo T, Li L, Zhao Q, Li W, Zheng J, Hong M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155899
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155899
Paeoniae Decoction restores intestinal barrier dysfunction by promoting the interaction between ILC3 and gut flora.
Huang S, Ye Q, Wang A, Chen Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155873
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155873
Theabrownin from Pu-erh Tea Improves DSS-Induced Colitis via Restoring Gut Homeostasis and Inhibiting TLR2&4 Signaling Pathway.
Zhao L, Zhao C, Miao Y, Lei S, Li Y, Gong J, Peng C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155852
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155852
Berberine and magnolol exert cooperative effects on ulcerative colitis in mice by self-assembling into carrier-free nanostructures.
Xu Y, Chen Z, Hao W, Yang Z, Farag M, Vong CT, Wang Y, Wang S
Journal of nanobiotechnology 2024 Sep 4;22(1):538
Journal of nanobiotechnology 2024 Sep 4;22(1):538
Knockdown of HSPA13 Inhibits TGFβ1-Induced Epithelial-Mesenchymal Transition of RPE by Suppressing the PI3K/Akt Signaling Pathway.
Gao F, Li M, Zhu L, Li J, Xu J, Jia S, Ou Q, Jin C, Tian H, Wang J, Xu J, Xu W, Xu GT, Lu L
Investigative ophthalmology & visual science 2024 Sep 3;65(11):1
Investigative ophthalmology & visual science 2024 Sep 3;65(11):1
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
Yan X, Bai X, Fu R, Duan Z, Zeng W, Zhu C
Food & function 2024 Sep 16;15(18):9037-9052
Food & function 2024 Sep 16;15(18):9037-9052
hucMSC-Ex alleviates inflammatory bowel disease in mice by enhancing M2-type macrophage polarization via the METTL3-Slc37a2-YTHDF1 axis.
Xu X, Peng J, Wang N, Ocansey DKW, Zhang X, Mao F
Cell biology and toxicology 2024 Sep 11;40(1):74
Cell biology and toxicology 2024 Sep 11;40(1):74
MicroRNA-522-3p promotes brain metastasis in non-small cell lung cancer by targeting Tensin 1 and modulating blood-brain barrier permeability.
Liu Q, Bao H, Zhang S, Li C, Sun G, Sun X, Fu T, Wang Y, Liang P
Experimental cell research 2024 Sep 1;442(1):114199
Experimental cell research 2024 Sep 1;442(1):114199
Combined effects of TiO(2) nanoparticle and fipronil co-exposure on microbiota in mouse intestine.
Wang C, Liu Y, He Y, Li J, Cao Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114931
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114931
PPARγ/NF-κB axis contributes to cold-induced resolution of experimental colitis and preservation of intestinal barrier.
Di Y, Li H, Yang J, Feng M, Wang S, Li W, Wang X, Zhu Y, Shi Y, Feng R, Qu B
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167326
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167326
Protective Effect of Protocatechuic Aldehyde on Cerebral Ischemia/Reperfusion Injury in Rats through Blood-Brain Barrier Protection.
He F, Feng J, Sun H, Xu Y, Yan H, Song X, Wang Y, Li X, Lin Q
Bulletin of experimental biology and medicine 2024 Oct;177(6):763-769
Bulletin of experimental biology and medicine 2024 Oct;177(6):763-769
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
Niu R, Lan J, Liang D, Xiang L, Wu J, Zhang X, Li Z, Chen H, Geng L, Xu W, Gong S, Yang M
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
Kiwifruit Polysaccharides Alleviate Ulcerative Colitis via Regulating Gut Microbiota-Dependent Tryptophan Metabolism and Promoting Colon Fucosylation.
Li Y, Han Y, Wang X, Yang X, Ren D
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23859-23874
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23859-23874
Gut Lactococcus garvieae promotes protective immunity to foodborne Clostridium perfringens infection.
Wang X-Y, Meng F-H, Zhang M-Y, Li F-X, Lei Y-X, Ma Z-G, Li J-Q, Lou Y-N, Chu Y-F, Ma K, Yu S-X
Microbiology spectrum 2024 Oct 3;12(10):e0402523
Microbiology spectrum 2024 Oct 3;12(10):e0402523
DHA-enriched phosphatidylserine ameliorates cyclophosphamide-induced liver injury via regulating the gut-liver axis.
Zhang H, Lu Y, Zhang Y, Dong J, Jiang S, Tang Y
International immunopharmacology 2024 Oct 25;140:112895
International immunopharmacology 2024 Oct 25;140:112895
WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis.
Tan L, Fan Y, Xu X, Zhang T, Cao X, Zhang C, Liang J, Hou Y, Dou H
Arthritis research & therapy 2024 Oct 23;26(1):183
Arthritis research & therapy 2024 Oct 23;26(1):183
Therapeutic Potential of Foodborne Indole Derived from Chinese Stinky Tofu in Reducing Intestinal Inflammation and Enhancing Barrier Function to Mitigate Alcoholic Liver Injury.
Peng Q, Zheng H, Quan L, Li S, Huang J, Li J, Xie G
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21829-21842
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21829-21842
Identification of COL3A1 as a candidate protein involved in the crosstalk between obesity and diarrhea using quantitative proteomics and machine learning.
Wang Y, Wang X, Niu X, Han K, Ru N, Xiang J, Linghu E
European journal of pharmacology 2024 Oct 15;981:176881
European journal of pharmacology 2024 Oct 15;981:176881
Increased SPARC in brain microvessels of ob/ob mice accelerates molecular transport into the brain accompany with albumin.
Tsurudome Y, Takahata Y, Morita N, Yamauchi S, Iyoda T, Horiguchi M, Ushijima K
Life sciences 2024 Oct 15;355:122990
Life sciences 2024 Oct 15;355:122990
NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice.
Ali M, Ullah H, Farooqui NA, Deng T, Siddiqui NZ, Ilyas M, Ali S, Rahman MU, Rehman AU, Alioui Y, Wang L, Yi X
Heliyon 2024 Oct 15;10(19):e38370
Heliyon 2024 Oct 15;10(19):e38370
Cadmium Induces Vascular Endothelial Cell Detachment by Downregulating Claudin-5 and ZO-1 Levels.
Hara T, Asatsu M, Yamagishi T, Ohata C, Funatsu H, Takahashi Y, Shirai M, Nakata C, Katayama H, Kaji T, Fujie T, Yamamoto C
International journal of molecular sciences 2024 Oct 14;25(20)
International journal of molecular sciences 2024 Oct 14;25(20)
Yam protein ameliorates cyclophosphamide-induced intestinal immunosuppression by regulating gut microbiota and its metabolites.
Lu J, Qin H, Liang L, Fang J, Hao K, Song Y, Sun T, Hui G, Xie Y, Zhao Y
International journal of biological macromolecules 2024 Nov;279(Pt 4):135415
International journal of biological macromolecules 2024 Nov;279(Pt 4):135415
Human placental mesenchymal stem cells transplantation repairs the alveolar epithelial barrier to alleviate lipopolysaccharides-induced acute lung injury.
Yu W, Lv Y, Xuan R, Han P, Xu H, Ma X
Biochemical pharmacology 2024 Nov;229:116547
Biochemical pharmacology 2024 Nov;229:116547
Oridonin alleviates cigarette smoke-induced nasal polyp formation by promoting autophagy.
Liu P, Wu X, Lv H, Huang J, Gu T, Liu D, Xu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117547
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117547
The role of the microbiota-gut-brain axis in methamphetamine-induced neurotoxicity: Disruption of microbial composition and short-chain fatty acid metabolism.
Chen L, Zhang K, Liu J, Li X, Liu Y, Ma H, Yang J, Li J, Chen L, Hsu C, Zeng J, Xie X, Wang Q
Acta pharmaceutica Sinica. B 2024 Nov;14(11):4832-4857
Acta pharmaceutica Sinica. B 2024 Nov;14(11):4832-4857
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
Feng YL, Xu XR, Zhu QM, Chang J, Zhang HL, Wang N, Sun JB, Liu J, Zhang J, Sun CP
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
The gut microbial metabolite indole-3-aldehyde alleviates impaired intestinal development by promoting intestinal stem cell expansion in weaned piglets.
Zhang J, Chen Y, Guo X, Li X, Zhang R, Wang M, Zhu W, Yu K
Journal of animal science and biotechnology 2024 Nov 8;15(1):150
Journal of animal science and biotechnology 2024 Nov 8;15(1):150
Gut commensal Parabacteroides distasonis exerts neuroprotective effects in acute ischemic stroke with hyperuricemia via regulating gut microbiota-gut-brain axis.
Wei H, Zhan L, Lv X, Lin Y, Zheng J, Yang W, Liu J, Sun J, Chen S
Journal of translational medicine 2024 Nov 5;22(1):999
Journal of translational medicine 2024 Nov 5;22(1):999
Differential Roles of Astrocytic CSF1 in Alzheimer's Disease and Cerebral Amyloid Angiopathy: Insights from Transcriptomic Analysis.
Li C, Chen Y, Luo S, Yang Y, Liu X, Li S, Ge W, Han C
Aging and disease 2024 Nov 5;16(5):3137-3153
Aging and disease 2024 Nov 5;16(5):3137-3153
The Hydrophobic Amino Acid-Rich Fish Collagen Peptide Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice via Repairing the Intestinal Barrier, Regulating Intestinal Flora and AA Metabolism.
Yang L, Wang Y, Li X, Chen Y, Liang J, He L, Jiang D, Huang S, Hou S
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25690-25703
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25690-25703
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
Yang W, Zhang X, Wang Z, Zheng X, Wu W, Chen Q
International immunopharmacology 2024 Nov 15;141:112883
International immunopharmacology 2024 Nov 15;141:112883
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Xu F, Xin Q, Ren M, Shi P, Wang B
Neurochemistry international 2024 May;175:105702
Neurochemistry international 2024 May;175:105702
Unveiling the Novel Benefits of Co-Administering Butyrate and Active Vitamin D3 in Mice Subjected to Chemotherapy-Induced Gut-Derived Pseudomonas aeruginosa Sepsis.
Huang FC, Huang SC
Biomedicines 2024 May 7;12(5)
Biomedicines 2024 May 7;12(5)
The rhizomes of Atractylodes macrocephala Koidz improve gastrointestinal health and pregnancy outcomes in pregnant mice via modulating intestinal barrier and water-fluid metabolism.
Chenxing W, Jie S, Yajuan T, Ting L, Yuying Z, Suhong C, Guiyuan L
Journal of ethnopharmacology 2024 May 23;326:117971
Journal of ethnopharmacology 2024 May 23;326:117971
Shaoyao decoction improves damp-heat colitis by activating the AHR/IL-22/STAT3 pathway through tryptophan metabolism driven by gut microbiota.
Zhang Y, Han L, Dong J, Yuan Z, Yao W, Ji P, Hua Y, Wei Y
Journal of ethnopharmacology 2024 May 23;326:117874
Journal of ethnopharmacology 2024 May 23;326:117874
miRNA Expression Analysis of IPEC-J2 Cells Damaged by Soybean 7S Globulin Reveals ssc-miR-221-5p as the Factor Alleviating Cell Damage.
Deng H, Ye T, Deng Y, Cui Y, Guo H, Deng J
Journal of agricultural and food chemistry 2024 May 22;72(20):11694-11705
Journal of agricultural and food chemistry 2024 May 22;72(20):11694-11705
Tryptophan metabolites relieve intestinal Candida albicans infection by altering the gut microbiota to reduce IL-22 release from group 3 innate lymphoid cells of the colon lamina propria.
Peng Z, Zhang J, Zhang M, Yin L, Zhou Z, Lv C, Wang Z, Tang J
Food & function 2024 May 20;15(10):5364-5381
Food & function 2024 May 20;15(10):5364-5381
Nicotinamide Supplementation Mitigates Oxidative Injury of Bovine Intestinal Epithelial Cells through Autophagy Modulation.
Guo Y, Feng C, Zhang Y, Hu K, Wang C, Wei X
Animals : an open access journal from MDPI 2024 May 16;14(10)
Animals : an open access journal from MDPI 2024 May 16;14(10)
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
Liu S, Hu H, Zhang M, Zhang Y, Geng R, Jin Y, Cao Y, Guo W, Liu J, Fu S
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
The therapeutic effects of traditional Chinese medicine on insulin resistance in obese mice by modulating intestinal functions.
Ma L, Bai Y, Liu J, Gong K, He Q, Zhao J, Suo Y, Wang W, Chen G, Lu Z
Heliyon 2024 May 15;10(9):e30379
Heliyon 2024 May 15;10(9):e30379
High-intensity exercise impairs intestinal barrier function by generating oxidative stress.
Takami M, Aoi W, Matsumoto K, Kato Y, Kobayashi Y, Kuwahata M
Journal of clinical biochemistry and nutrition 2024 Mar;74(2):136-140
Journal of clinical biochemistry and nutrition 2024 Mar;74(2):136-140
Narirutin Attenuates Cerebral Ischemia-Reperfusion Injury by Suppressing the TXNIP/NLRP3 Pathway.
Luo L, Wang S, Liu W, Zhang Z, Zhao M, Liu A
Neurochemical research 2024 Mar;49(3):692-705
Neurochemical research 2024 Mar;49(3):692-705
Suppression of neutrophil extracellular traps is responsible for the amelioration of chemotherapeutic intestinal injury by the natural compound PEITC.
Bai M, Li S, Zhang C, An N, Wang J, Qin J, Jia R, Liu W, Cheng J, Wu X, Xu Q
Toxicology and applied pharmacology 2024 Mar;484:116857
Toxicology and applied pharmacology 2024 Mar;484:116857
Inhibition of EphA4 reduces vasogenic edema after experimental stroke in mice by protecting the blood-brain barrier integrity.
Zhang S, Zhao J, Sha WM, Zhang XP, Mai JY, Bartlett PF, Hou ST
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Mar;44(3):419-433
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Mar;44(3):419-433
OR11H1 Missense Variant Confers the Susceptibility to Vogt-Koyanagi-Harada Disease by Mediating Gadd45g Expression.
Li X, Wang G, Wang X, Li W, Li N, Liu X, Fan W, He S, Han Y, Su G, Cao Q, Yang P, Hou S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(11):e2306563
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(11):e2306563
Interleukin-22 Contributes to Blood-Brain Barrier Disruption via STAT3/VEGFA Activation in Escherichia coli Meningitis.
Yang R, Chen J, Qu X, Liu H, Wang X, Tan C, Chen H, Wang X
ACS infectious diseases 2024 Mar 8;10(3):988-999
ACS infectious diseases 2024 Mar 8;10(3):988-999
Xylooligosaccharides ameliorate insulin resistance by increasing Akkermansia muciniphila and improving intestinal barrier dysfunction in gestational diabetes mellitus mice.
Yang J, Wang J, Wu W, Su C, Wu Y, Li Q
Food & function 2024 Mar 18;15(6):3122-3129
Food & function 2024 Mar 18;15(6):3122-3129
Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline-Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora.
Cao Y, Leng C, Lin K, Li Y, Zhou M, Zhou M, Shu X, Liu W
Molecules (Basel, Switzerland) 2024 Mar 16;29(6)
Molecules (Basel, Switzerland) 2024 Mar 16;29(6)
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Teng S, Yang Y, Zhang W, Li X, Li W, Cui Z, Min L, Wu J
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis.
Tansey MG, Boles J, Holt J, Cole C, Neighbarger N, Urs N, Uriarte-Huarte O
Research square 2024 Mar 12;
Research square 2024 Mar 12;
Sulforaphane decreases oxidative stress and inhibits NLRP3 inflammasome activation in a mouse model of ulcerative colitis.
Zhou ZJ, Dong JY, Qiu Y, Zhang GL, Wei K, He LH, Sun YN, Jiang HZ, Zhang SS, Guo XR, Wang JY, Chen DP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116706
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116706
The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.
Li B, Jiang XF, Dong YJ, Zhang YP, He XL, Zhou CL, Ding YY, Wang N, Wang YB, Cheng WQ, Jiang NH, Su J, Lv GY, Chen SH
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116519
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116519
Paeoniflorin ameliorates chronic colitis via the DR3 signaling pathway in group 3 innate lymphoid cells.
Huang S, Xie X, Xu B, Pan Z, Liang J, Zhang M, Pan S, Wang X, Zhao M, Wang Q, Chen J, Li Y, Zhou L, Luo X
Journal of pharmaceutical analysis 2024 Jun;14(6):100940
Journal of pharmaceutical analysis 2024 Jun;14(6):100940
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Bai X, Deng J, Duan Z, Fu R, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways.
Tian X, Li J, Liu S, Dong Q, Fu Y, Luo R, Sun Y, Guo L, Lu Q, Ye C, Liu J, Fu S, Qiu Y
Heliyon 2024 Jun 30;10(12):e33161
Heliyon 2024 Jun 30;10(12):e33161
Sarcandra glabra (Thunb.) Nakai alleviates DSS-induced ulcerative colitis by promoting restitution, restoring barrier function, and modulating IL-17/Notch1/FoxP3 pathway in intestinal cells.
Zhang S, Li Y, Chen G, Wang X, Wu B
Journal of ethnopharmacology 2024 Jun 28;328:118131
Journal of ethnopharmacology 2024 Jun 28;328:118131
Fucoxanthin alleviates lipopolysaccharide-induced intestinal barrier injury in mice.
Du L, Chen C, Yang YH, Zheng Y, Li H, Wu ZJ, Wu H, Miyashita K, Su GH
Food & function 2024 Jun 17;15(12):6359-6373
Food & function 2024 Jun 17;15(12):6359-6373
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy.
Cao C, Zhang H, He Z, Zhang K, Qian Z, Shen J, Zheng L, Xue M, Sun S, Li C, Zhao W, Jing J, Ma R, Ge X, Yao B
Lipids in health and disease 2024 Jun 11;23(1):180
Lipids in health and disease 2024 Jun 11;23(1):180
Exposure to hexa(fl)uoropropylene oxide trimer acid (HFPO-TA) impairs 5-HT metabolism by impacting the brain-gut axis in mice.
Xie X, Sun L, Xu H, Zhang M, Zhou J, Du S, Hu Q, Li Z
Chemosphere 2024 Jul;359:142035
Chemosphere 2024 Jul;359:142035
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Lu J, Liu G, Sun W, Jia G, Zhao H, Chen X, Wang J
The Journal of nutrition 2024 Jul;154(7):2087-2096
The Journal of nutrition 2024 Jul;154(7):2087-2096
The Use of Polysaccharide AOP30 from the Rhizome of Alpinia officinarum Hance to Alleviate Lipopolysaccharide-Induced Intestinal Epithelial Barrier Dysfunction and Inflammation via the TLR4/NfκB Signaling Pathway in Caco-2 Cell Monolayers.
Jia X, Huang Y, Liu G, Li Z, Tan Q, Zhong S
Nutrients 2024 Jul 5;16(13)
Nutrients 2024 Jul 5;16(13)
Study on the mechanism of mitigating radiation damage by improving the hematopoietic system and intestinal barrier with Tenebrio molitor peptides.
Shang Y, Cui P, Chen Y, Zhang Z, Li S, Chen Z, Ma A, Jia Y
Food & function 2024 Jul 29;15(15):8116-8127
Food & function 2024 Jul 29;15(15):8116-8127
Simultaneous ischemic regions targeting and BBB crossing strategy to harness extracellular vesicles for therapeutic delivery in ischemic stroke.
Liang HB, Chen X, Zhao R, Li SJ, Huang PS, Tang YH, Cui GH, Liu JR
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1037-1057
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1037-1057
PSD-95 inhibitor Tat-NR2B9c (NA-1) protects the integrity of the blood-brain barrier after transient middle artery occlusion in rats by downregulating matrix metalloprotease-9 and upregulating endothelial nitric oxide synthase.
Xu Y, Xu L, Xu C, Zhao M, Xu T, Xia L, Wu Y, Cao Y, Han Z
Brain research bulletin 2024 Jan;206:110836
Brain research bulletin 2024 Jan;206:110836
Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken.
Liu L, Gong X, Zhang X, Zhang D, Tang Y, Liu J, Li Y, Pan D
Poultry science 2024 Jan;103(1):103242
Poultry science 2024 Jan;103(1):103242
Inhibition of circulating exosomes release with GW4869 mitigates severe acute pancreatitis-stimulated intestinal barrier damage through suppressing NLRP3 inflammasome-mediated pyroptosis.
Shao Y, Jiang Y, Wang J, Li H, Li C, Zhang D
International immunopharmacology 2024 Jan 5;126:111301
International immunopharmacology 2024 Jan 5;126:111301
The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway.
Zhou L, Yang Y, Fu X, Xia B, Li C, Lu C, Qi Y, Zhang H, Liu T
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117100
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117100
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
Cui L, Zou S, Liu J, Lv H, Li H, Zhang Z
International immunopharmacology 2024 Jan 25;127:111404
International immunopharmacology 2024 Jan 25;127:111404
Canonical and Non-Canonical Localization of Tight Junction Proteins during Early Murine Cranial Development.
Mak S, Hammes A
International journal of molecular sciences 2024 Jan 24;25(3)
International journal of molecular sciences 2024 Jan 24;25(3)
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.
Yang R, Wang X, Liu H, Chen J, Tan C, Chen H, Wang X
Cell communication and signaling : CCS 2024 Jan 17;22(1):44
Cell communication and signaling : CCS 2024 Jan 17;22(1):44
Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis.
Wei Y, Li J, Li J, Liu C, Guo X, Liu Z, Zhang L, Bao S, Wu X, Su W, Wang X, Zhang J, Dong W
Cell death & disease 2024 Jan 17;15(1):60
Cell death & disease 2024 Jan 17;15(1):60
Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway.
Wu S, Du W, Wu Z, Wen F, Zhong X, Huang X, Gu H, Wang J
Ecotoxicology and environmental safety 2024 Jan 15;270:115887
Ecotoxicology and environmental safety 2024 Jan 15;270:115887
Baitouweng decoction repairs the intestinal barrier in DSS-induced colitis mice via regulation of AMPK/mTOR-mediated autophagy.
Pan SM, Wang CL, Hu ZF, Zhang ML, Pan ZF, Zhou RY, Wang XJ, Huang SW, Li YY, Wang Q, Luo X, Zhou L, Hou JT, Chen B
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116888
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116888
Gut Microbiota Plays Essential Roles in Soyasaponin's Preventive Bioactivities against Steatohepatitis in the Methionine and Choline Deficient (MCD) Diet-Induced Non-Alcoholic Steatohepatitis (NASH) Mice.
Su C, Wang J, Luo H, Chen J, Lin F, Mo J, Xiong F, Zha L
Molecular nutrition & food research 2024 Feb;68(4):e2300561
Molecular nutrition & food research 2024 Feb;68(4):e2300561
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Li Z, Wang B, Tian L, Zheng B, Zhao X, Liu R
Inflammation 2024 Feb;47(1):376-389
Inflammation 2024 Feb;47(1):376-389
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
Hui H, Wang Z, Zhao X, Xu L, Yin L, Wang F, Qu L, Peng J
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
Neuron Derived Cold-Inducible RNA-Binding Protein Promotes NETs Formation to Exacerbate Brain Endothelial Barrier Disruption after Ischemic Stroke.
Li Z, Sun S, Xiao Q, Tan S, Jin H, Hu B
Aging and disease 2024 Feb 4;16(1):520-539
Aging and disease 2024 Feb 4;16(1):520-539
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice.
Yang YH, Chen C, Zheng Y, Wu ZJ, Zhou MQ, Liu XY, Miyashita K, Duan DL, Du L
Journal of agricultural and food chemistry 2024 Feb 28;72(8):4142-4154
Journal of agricultural and food chemistry 2024 Feb 28;72(8):4142-4154
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.
Jia L, Liu X, Liu X, Guan Q, Tian Y, Li J, Zhao P
Chinese medicine 2024 Feb 28;19(1):32
Chinese medicine 2024 Feb 28;19(1):32
The microbial metabolite urolithin A reduces Clostridioides difficile toxin expression and toxin-induced epithelial damage.
Ghosh S, Erickson D, Chua MJ, Collins J, Jala VR
mSystems 2024 Feb 20;9(2):e0125523
mSystems 2024 Feb 20;9(2):e0125523
Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway.
Zhang Y, Tu S, Ji X, Wu J, Meng J, Gao J, Shao X, Shi S, Wang G, Qiu J, Zhang Z, Hua C, Zhang Z, Chen S, Zhang L, Zhu SJ
Nature communications 2024 Feb 13;15(1):1333
Nature communications 2024 Feb 13;15(1):1333
Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis.
Boles JS, Holt J, Cole CL, Neighbarger NK, Urs NM, Huarte OU, Tansey MG
bioRxiv : the preprint server for biology 2024 Feb 13;
bioRxiv : the preprint server for biology 2024 Feb 13;
Inulin alleviates perfluorooctanoic acid-induced intestinal injury in mice by modulating the PI3K/AKT/mTOR signaling pathway.
Zhang QY, Zhong MT, Gi M, Chen YK, Lai MQ, Liu JY, Liu YM, Wang Q, Xie XL
Environmental pollution (Barking, Essex : 1987) 2024 Feb 1;342:123090
Environmental pollution (Barking, Essex : 1987) 2024 Feb 1;342:123090
Rehmannia glutinosa polysaccharides enhance intestinal immunity of mice through regulating the microbiota.
Yu L, Lin F, Yu Y, Deng X, Shi X, Lu X, Lu Y, Wang D
International journal of biological macromolecules 2024 Dec;283(Pt 3):137878
International journal of biological macromolecules 2024 Dec;283(Pt 3):137878
Ganjiang Huangqin Huanglian Renshen Decoction protects against ulcerative colitis by modulating inflammation, oxidative stress, and gut microbiota.
Zhou C, Peng B, Zhang M, Yang Y, Yi Z, Wu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156172
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156172
Resistant starch confers protection of dietary against diabetic cardiomyopathy.
Zhu Q, Lu X, Zhang T, Shi M, Gao R, Zhou Y, Zhang H, Yao W, Qi C, Liao S, Li X
The Journal of nutritional biochemistry 2024 Dec;134:109766
The Journal of nutritional biochemistry 2024 Dec;134:109766
An In Vitro Model of the Blood-Brain Barrier for the Investigation and Isolation of the Key Drivers of Barriergenesis.
Schofield C, Sarrigiannidis S, Moran-Horowich A, Jackson E, Rodrigo-Navarro A, van Agtmael T, Cantini M, Dalby MJ, Salmeron-Sanchez M
Advanced healthcare materials 2024 Dec;13(32):e2303777
Advanced healthcare materials 2024 Dec;13(32):e2303777
Therapeutic Efficacy and Underlying Mechanisms of a Mannoglucan from Hirsutella sinensis Mycelium on Dextran Sulfate Sodium-Induced Inflammatory Bowel Disease in Mice: Modulation of the Intestinal Barrier, Oxidative Stress and Gut Microbiota.
Ni W, Li Y, Feng J, Liu B, Yuan H, Tai G, Bi H
International journal of molecular sciences 2024 Dec 5;25(23)
International journal of molecular sciences 2024 Dec 5;25(23)
FGF20 modulates gut microbiota to mitigate dextran sodium sulfate-induced ulcerative colitis in mouse models.
Jin Z, Liu Z, Pan J, Wang S, Cui M, He C, Lin M, Liu X, Yu X, Gong F
International immunopharmacology 2024 Dec 5;142(Pt A):113044
International immunopharmacology 2024 Dec 5;142(Pt A):113044
Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability.
Yang Q, Wan Q, Wang Z
Scientific reports 2024 Dec 2;14(1):29848
Scientific reports 2024 Dec 2;14(1):29848
Inulin alleviates GenX-induced intestinal injury in mice by modulating the MAPK pathway, cell cycle, and cell adhesion proteins.
Zhang QY, Lai MQ, Chen YK, Zhong MT, Gi M, Wang Q, Xie XL
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124974
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124974
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
Dong J, Che J, Wu Y, Deng Y, Jiang X, He Z, Zhang J
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
Role of transient receptor potential vanilloid 4 channels in an ovalbumin-induced murine food allergic model.
Murayama Y, Tabuchi M, Utsumi D, Naruse K, Tokuyama K, Ikedo A, Morimasa E, Kato S, Matsumoto K
Naunyn-Schmiedeberg's archives of pharmacology 2024 Aug;397(8):6061-6074
Naunyn-Schmiedeberg's archives of pharmacology 2024 Aug;397(8):6061-6074
Gut microbiota is necessary for pair-housing to protect against post-stroke depression in mice.
Jiang ST, Sun YH, Li Y, Wang MQ, Wang XY, Dong YF
Experimental neurology 2024 Aug;378:114834
Experimental neurology 2024 Aug;378:114834
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
Xue W, Tianrun W, Jiaqi Y, Xin L, Ruxue D, Peng Z
Ecotoxicology and environmental safety 2024 Aug;281:116636
Ecotoxicology and environmental safety 2024 Aug;281:116636
Chitosan-alginate/R8 ternary polyelectrolyte complex as an oral protein-based vaccine candidate induce effective mucosal immune responses.
Liu Y, Long M, Wang Y, Liang Z, Dong Y, Qu M, Ge X, Nan Y, Chen Y, Zhou X
International journal of biological macromolecules 2024 Aug;275(Pt 2):133671
International journal of biological macromolecules 2024 Aug;275(Pt 2):133671
The dual effects of dexmedetomidine on intestinal barrier and intestinal motility during sepsis.
Cao YY, Wang ZH, Pan YJ, Qi YP, Chen Q, Qin XM, Wang T, Shen GG, Jiang XG, Lu WH
Surgery 2024 Aug;176(2):379-385
Surgery 2024 Aug;176(2):379-385
Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration.
Yang H, Zhou C, Nie S, Xu S, Li M, Yu Q, Wei Y, Wang X
Molecular immunology 2024 Aug;172:23-37
Molecular immunology 2024 Aug;172:23-37
Nur77 as a novel regulator of Paneth cell differentiation and function.
Cui C, Wang X, Zheng Y, Wu L, Li L, Wei H, Peng J
Mucosal immunology 2024 Aug;17(4):752-767
Mucosal immunology 2024 Aug;17(4):752-767
The Phospholipid Flippase ATP8B1 is Involved in the Pathogenesis of Ulcerative Colitis via Establishment of Intestinal Barrier Function.
Koelink PJ, Gómez-Mellado VE, Duijst S, van Roest M, Meisner S, Ho-Mok KS, Frank S, Appelman BS, Bloemendaal LT, Vogel GF, van de Graaf SFJ, Bosma PJ, Oude Elferink RPJ, Wildenberg ME, Paulusma CC
Journal of Crohn's & colitis 2024 Aug 6;18(7):1134-1146
Journal of Crohn's & colitis 2024 Aug 6;18(7):1134-1146
Butylparaben induces glycolipid metabolic disorders in mice via disruption of gut microbiota and FXR signaling.
Du H, Cui L, Zhao X, Yu Z, He T, Zhang B, Fan X, Zhao M, Zhu R, Zhang Z, Li M, Li J, Oh Y, Gu N
Journal of hazardous materials 2024 Aug 5;474:134821
Journal of hazardous materials 2024 Aug 5;474:134821
Indole-3-aldehyde Alleviates High-Fat Diet-Induced Gut Barrier Disruption by Increasing Intestinal Stem Cell Expansion.
Zhang J, Zhang R, Chen Y, Guo X, Ren Y, Wang M, Li X, Huang Z, Zhu W, Yu K
Journal of agricultural and food chemistry 2024 Aug 28;72(34):18930-18941
Journal of agricultural and food chemistry 2024 Aug 28;72(34):18930-18941
Dietary rutin improves the antidiarrheal capacity of weaned piglets by improving intestinal barrier function, antioxidant capacity and cecal microbiota composition.
Ma L, Zhou B, Liu H, Chen S, Zhang J, Wang T, Wang C
Journal of the science of food and agriculture 2024 Aug 15;104(10):6262-6275
Journal of the science of food and agriculture 2024 Aug 15;104(10):6262-6275
Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology.
Liu K, Yin Y, Shi C, Yan C, Zhang Y, Qiu L, He S, Li G
Phytotherapy research : PTR 2024 Apr;38(4):2023-2040
Phytotherapy research : PTR 2024 Apr;38(4):2023-2040
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
Yu X, Nie W, Chen X, Zou LF, Xu BC, Chen CG
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
Qing-Re-Chu-shi decoction ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice through anti-inflammation and immunoregulatory mechanisms.
Meng Y, Liu Y, Guo J, Guo X, Han X, Zhang L, Di T, Zhao J, Wang Y, Li P
Journal of ethnopharmacology 2024 Apr 6;323:117702
Journal of ethnopharmacology 2024 Apr 6;323:117702
Exploring the mechanism of Bushen Huoxue prescription in the treatment of early diabetic retinal edema from the perspective of inner blood-retinal barrier injury.
Li J, Guo X, Huang Y, Ren Y, Liang H, Xie X, Zhang M
Journal of ethnopharmacology 2024 Apr 6;323:117658
Journal of ethnopharmacology 2024 Apr 6;323:117658
Canagliflozin protects against hyperglycemia-induced cerebrovascular injury by preventing blood-brain barrier (BBB) disruption via AMPK/Sp1/adenosine A2A receptor.
Liu Z, Hua W, Jin S, Wang Y, Pang Y, Wang B, Zhao N, Song Y, Qi J
European journal of pharmacology 2024 Apr 5;968:176381
European journal of pharmacology 2024 Apr 5;968:176381
Tetrandrine Inhibits Cancer Stem Cell Characteristics and Epithelial to Mesenchymal Transition in Triple-Negative Breast Cancer via SOD1/ROS Signaling Pathway.
Liu T, Li K, Zhang Z, Peng J, Yang J, Law BYK, Liu X, Li W
The American journal of Chinese medicine 2023;51(2):425-444
The American journal of Chinese medicine 2023;51(2):425-444
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Chen Y, Zhang H, Li Y, Wang T
Oxidative medicine and cellular longevity 2023;2023:8258354
Oxidative medicine and cellular longevity 2023;2023:8258354
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
Ji Q, Li H, Cai Z, Yuan X, Pu X, Huang Y, Fu S, Chu L, Jiang C, Xue J, Zhang X, Li R
International journal of biological sciences 2023;19(6):1894-1909
International journal of biological sciences 2023;19(6):1894-1909
Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell Activity.
Rivera KR, Bliton RJ, Burclaff J, Czerwinski MJ, Liu J, Trueblood JM, Hinesley CM, Breau KA, Deal HE, Joshi S, Pozdin VA, Yao M, Ziegler AL, Blikslager AT, Daniele MA, Magness ST
Cellular and molecular gastroenterology and hepatology 2023;16(5):823-846
Cellular and molecular gastroenterology and hepatology 2023;16(5):823-846
Mahuang Fuzi Xixin decoction ameliorates allergic rhinitis and repairs the airway epithelial barrier by modulating the lung microbiota dysbiosis.
Wei X, Ding M, Liang X, Zhang B, Tan X, Zheng Z
Frontiers in microbiology 2023;14:1206454
Frontiers in microbiology 2023;14:1206454
Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.
Zhang P, Chen J, Ming Y, Niu Y
Frontiers in microbiology 2023;14:1153188
Frontiers in microbiology 2023;14:1153188
Circulating sepsis-related metabolite sphinganine could protect against intestinal damage during sepsis.
Wang Z, Qi Y, Wang F, Zhang B, Jianguo T
Frontiers in immunology 2023;14:1151728
Frontiers in immunology 2023;14:1151728
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Ma P, Huang N, Tang J, Zhou Z, Xu J, Chen Y, Zhang M, Huang Q, Cheng Y
Frontiers in pharmacology 2023;14:1098228
Frontiers in pharmacology 2023;14:1098228
Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury.
Jia J, Deng J, Jin H, Yang J, Nan D, Yu Z, Yu W, Shen Z, Lu Y, Liu R, Wang Z, Qu X, Qiu D, Yang Z, Huang Y
Frontiers in pharmacology 2023;14:1084564
Frontiers in pharmacology 2023;14:1084564
Maslinic acid alleviates LPS-induced mice mastitis by inhibiting inflammatory response, maintaining the integrity of the blood-milk barrier and regulating intestinal flora.
Li K, Ran X, Zeng Y, Li S, Hu G, Wang X, Li Y, Yang Z, Liu J, Fu S
International immunopharmacology 2023 Sep;122:110551
International immunopharmacology 2023 Sep;122:110551
Mitigation of maternal fecal microbiota transplantation on neurobehavioral deficits of offspring rats prenatally exposed to arsenic: Role of microbiota-gut-brain axis.
Zhao Q, Hao Y, Yang X, Mao J, Tian F, Gao Y, Tian X, Yan X, Qiu Y
Journal of hazardous materials 2023 Sep 5;457:131816
Journal of hazardous materials 2023 Sep 5;457:131816
DUOX2-Induced Oxidative Stress Inhibits Intestinal Angiogenesis through MMP3 in a Low-Birth-Weight Piglet Model.
Zou D, Yang Y, Ji F, Lv R, Xu T, Hu C
Antioxidants (Basel, Switzerland) 2023 Sep 25;12(10)
Antioxidants (Basel, Switzerland) 2023 Sep 25;12(10)
Resveratrol alleviates DSS-induced IBD in mice by regulating the intestinal microbiota-macrophage-arginine metabolism axis.
Xu X, Ocansey DKW, Pei B, Zhang Y, Wang N, Wang Z, Mao F
European journal of medical research 2023 Sep 2;28(1):319
European journal of medical research 2023 Sep 2;28(1):319
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Wang Y, Zhang J, Zhang B, Lu M, Ma J, Liu Z, Huang J, Ma J, Yang X, Wang F, Tang X
Journal of ethnopharmacology 2023 Sep 15;313:116538
Journal of ethnopharmacology 2023 Sep 15;313:116538
Treatment with Ligilactobacillus murinus lowers blood pressure and intestinal permeability in spontaneously hypertensive rats.
Mukohda M, Yano T, Matsui T, Nakamura S, Miyamae J, Toyama K, Mitsui R, Mizuno R, Ozaki H
Scientific reports 2023 Sep 14;13(1):15197
Scientific reports 2023 Sep 14;13(1):15197
Effects of DON on Mitochondrial Function, Endoplasmic Reticulum Stress, and Endoplasmic Reticulum Mitochondria Contact Sites in the Jejunum of Piglets.
Li X, Gou F, Xiao K, Zhu J, Lin Q, Yu M, Hong Q, Hu C
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13234-13243
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13234-13243
Cerebrospinal Fluid Pressure Reduction Induces Glia-Mediated Retinal Inflammation and Leads to Retinal Ganglion Cell Injury in Rats.
Cheng Y, Lin D, Wu S, Liu Q, Yan X, Ren T, Zhang J, Wang N
Molecular neurobiology 2023 Oct;60(10):5770-5788
Molecular neurobiology 2023 Oct;60(10):5770-5788
Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans.
Zong X, Zhang H, Zhu L, Deehan EC, Fu J, Wang Y, Jin M
Journal of advanced research 2023 Oct;52:203-218
Journal of advanced research 2023 Oct;52:203-218
Iguratimod promotes functional recovery after SCI by repairing endothelial cell tight junctions.
Wang Q, Yi J, Liu H, Luo M, Yin G, Huang Z
Experimental neurology 2023 Oct;368:114503
Experimental neurology 2023 Oct;368:114503
Lactiplantibacillus plantarum Strain FLPL05 Promotes Longevity in Mice by Improving Intestinal Barrier.
Yu X, Wei M, Yang D, Wu X, Wei H, Xu F
Probiotics and antimicrobial proteins 2023 Oct;15(5):1193-1205
Probiotics and antimicrobial proteins 2023 Oct;15(5):1193-1205
Lauric acid provides neuroprotection against oxidative stress in mouse model of hyperglycaemic stroke.
Shaheryar ZA, Khan MA, Hameed H, Zaidi SAA, Anjum I, Rahman MSU
European journal of pharmacology 2023 Oct 5;956:175990
European journal of pharmacology 2023 Oct 5;956:175990
Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier.
Mao A, Zhao W, Zhu Y, Kong F, Chen D, Si H, Xu C
Microorganisms 2023 Oct 24;11(11)
Microorganisms 2023 Oct 24;11(11)
Atractylodes lancea Rhizome Polysaccharide Alleviates Immunosuppression and Intestinal Mucosal Injury in Mice Treated with Cyclophosphamide.
Wang D, Dong Y, Xie Y, Xiao Y, Ke C, Shi K, Zhou Z, Tu J, Qu L, Liu Y
Journal of agricultural and food chemistry 2023 Oct 20;
Journal of agricultural and food chemistry 2023 Oct 20;
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Tung TH, Lai WD, Lee HC, Su KP, Panunggal B, Huang SY
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin).
Wang K, Kong F, Qiu Y, Chen T, Fu J, Jin X, Su Y, Gu Y, Hu Z, Li J
Autophagy 2023 Nov;19(11):2934-2957
Autophagy 2023 Nov;19(11):2934-2957
Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis.
Chen T, Zhang L, Yao L, Luan J, Zhou X, Cong R, Guo X, Qin C, Song N
Environment international 2023 Nov;181:108292
Environment international 2023 Nov;181:108292
Fecal microbiota transplantation combined with prebiotics ameliorates ulcerative colitis in mice.
Qian X, Jiang H, Wu Y, Shao H, He W, He Y, Bao X, He L, Jia Y, Xu Z
Future microbiology 2023 Nov;18:1251-1263
Future microbiology 2023 Nov;18:1251-1263
Kaempferol ameliorated alcoholic liver disease through inhibiting hepatic bile acid synthesis by targeting intestinal FXR-FGF15 signaling.
Xiao L, Xu G, Chen S, He Y, Peng F, Yuan C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155055
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155055
Aqueous Extract of Brassica rapa L.'s Impact on Modulating Exercise-Induced Fatigue via Gut-Muscle Axis.
Wang C, Zhu H, Cheng Y, Guo Y, Zhao Y, Qian H
Nutrients 2023 Nov 9;15(22)
Nutrients 2023 Nov 9;15(22)
Cingulin regulates hair cell cuticular plate morphology and is required for hearing in human and mouse.
Zhu GJ, Huang Y, Zhang L, Yan K, Qiu C, He Y, Liu Q, Zhu C, Morín M, Moreno-Pelayo MÁ, Zhu MS, Cao X, Zhou H, Qian X, Xu Z, Chen J, Gao X, Wan G
EMBO molecular medicine 2023 Nov 8;15(11):e17611
EMBO molecular medicine 2023 Nov 8;15(11):e17611
PE (0:0/14:0), an endogenous metabolite of the gut microbiota, exerts protective effects against sepsis-induced intestinal injury by modulating the AHR/CYP1A1 pathway.
Tian WZ, Yue Q, Fei W, Yao PZ, Han RQ, Tang J
Clinical science (London, England : 1979) 2023 Nov 29;137(22):1753-1769
Clinical science (London, England : 1979) 2023 Nov 29;137(22):1753-1769
Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions.
Zhou L, Lao Z, Fan X, Hao M, Yang Y
Bioscience, biotechnology, and biochemistry 2023 May 19;87(6):627-637
Bioscience, biotechnology, and biochemistry 2023 May 19;87(6):627-637
Chloroquine Protects Hypoxia/Ischemia-Induced Neonatal Brain Injury in Rats by Mitigating Blood-Brain Barrier Disruption.
Fang M, Liu J, Zhang Z, Li Y, Zhu J, Lin Z
ACS chemical neuroscience 2023 May 17;14(10):1764-1773
ACS chemical neuroscience 2023 May 17;14(10):1764-1773
Cysteamine and N-Acetyl-cysteine Alleviate Placental Oxidative Stress and Barrier Function Damage Induced by Deoxynivalenol.
Huang S, Zhang L, Luo J, Wu D, Ma K, Chen Y, Ma S, Feng L, Li F, Liu D, Deng J, Tan C
Journal of agricultural and food chemistry 2023 May 10;71(18):6846-6858
Journal of agricultural and food chemistry 2023 May 10;71(18):6846-6858
Molecular Mechanisms Associated with Protecting IEC-6 Cells from Acrylamide-Induced Tight Junction Damage by Ganoderma atrum Polysaccharide.
Lu J, Yang Y, Varga E, Marko D, Yu Q, Xie J, Li C, Chen Y
Molecular nutrition & food research 2023 Mar;67(6):e2200774
Molecular nutrition & food research 2023 Mar;67(6):e2200774
The Polo-Like Kinase 1-Mammalian Target of Rapamycin Axis Regulates Autophagy to Prevent Intestinal Barrier Dysfunction During Sepsis.
Cao YY, Qiao Y, Wang ZH, Chen Q, Qi YP, Lu ZM, Wang Z, Lu WH
The American journal of pathology 2023 Mar;193(3):296-312
The American journal of pathology 2023 Mar;193(3):296-312
Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation.
Ning W, Gao G, Zhou Y, Li WQ, Yang HH, Duan XB, Li X, Gong YB, Li D, Guo R
International immunopharmacology 2023 Mar;116:109747
International immunopharmacology 2023 Mar;116:109747
Cimifugin suppresses type 2 airway inflammation by binding to SPR and regulating its protein expression in a non-enzymatic manner.
Gu X, Chen Y, Qian P, He T, Wu Y, Lin W, Zheng J, Hong M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154657
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154657
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Zhao S, Hu S, Sun K, Luo L, Zeng L
Food & function 2023 Mar 6;14(5):2313-2325
Food & function 2023 Mar 6;14(5):2313-2325
Foodborne Carbon Dot Exposure Induces Insulin Resistance through Gut Microbiota Dysbiosis and Damaged Intestinal Mucus Layer.
Zhang B, Fan X, Du H, Zhao M, Zhang Z, Zhu R, He B, Zhang Y, Li X, Li J, Gu N
ACS nano 2023 Mar 28;17(6):6081-6094
ACS nano 2023 Mar 28;17(6):6081-6094
Beneficial Effects of Hordenine on a Model of Ulcerative Colitis.
Xu Z, Zhang Q, Ding C, Wen F, Sun F, Liu Y, Tao C, Yao J
Molecules (Basel, Switzerland) 2023 Mar 21;28(6)
Molecules (Basel, Switzerland) 2023 Mar 21;28(6)
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Wei R, Su Z, Mackenzie GG
Food & function 2023 Mar 20;14(6):2684-2697
Food & function 2023 Mar 20;14(6):2684-2697
Swimming training combined with fecal microbial transplantation protects motor functions in rats with spinal cord injury by improving the intestinal system.
Ouyang S, Wang X, Chen Y, Deng L, Yang X, Hu S, Wu S
Neuroscience letters 2023 Mar 16;799:137104
Neuroscience letters 2023 Mar 16;799:137104
Chitosan oligosaccharide alleviates and removes the toxicological effects of organophosphorus pesticide chlorpyrifos residues.
Fu H, Liu H, Ge Y, Chen Y, Tan P, Bai J, Dai Z, Yang Y, Wu Z
Journal of hazardous materials 2023 Mar 15;446:130669
Journal of hazardous materials 2023 Mar 15;446:130669
Compatibility between cold-natured medicine CP and hot-natured medicine AZ synergistically mitigates colitis mice through attenuating inflammation and restoring gut barrier.
Li YY, He YX, Wu YQ, Liu C, Ren LZ, Lu XY, Wang YM, Yu Y
Journal of ethnopharmacology 2023 Mar 1;303:115902
Journal of ethnopharmacology 2023 Mar 1;303:115902
Therapeutic effects of Zhuling Jianpi capsule on experimental ulcerative colitis and characterization of its chemical constituents and metabolomics using UHPLC-Q-TOF-MS.
Li J, Zhou Z, Liu D, Dong H, Zhou J, Wu J
Heliyon 2023 Jun;9(6):e16553
Heliyon 2023 Jun;9(6):e16553
Circulating exosomal miR-155-5p contributes to severe acute pancreatitis-associated intestinal barrier injury by targeting SOCS1 to activate NLRP3 inflammasome-mediated pyroptosis.
Shao Y, Li Y, Jiang Y, Li H, Wang J, Zhang D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jun;37(6):e23003
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jun;37(6):e23003
Non-Invasive and Label-Free On-Chip Impedance Monitoring of Heatstroke.
Zhao Y, Fan W, Liu A, Pan S, Xu C, Peng H, Yin B, Wang X, Dong J, Pan Z
Biosensors 2023 Jun 27;13(7)
Biosensors 2023 Jun 27;13(7)
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
Qiao N, An Z, Fu Z, Chen X, Tong Q, Zhang Y, Ren H
European journal of pharmacology 2023 Jun 15;949:175717
European journal of pharmacology 2023 Jun 15;949:175717
Gut Microbiota Taxon-Dependent Transformation of Microglial M1/M2 Phenotypes Underlying Mechanisms of Spatial Learning and Memory Impairment after Chronic Methamphetamine Exposure.
Wu Y, Dong Z, Jiang X, Qu L, Zhou W, Sun X, Hou J, Xu H, Cheng M
Microbiology spectrum 2023 Jun 15;11(3):e0030223
Microbiology spectrum 2023 Jun 15;11(3):e0030223
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Liu J, Fu L, Yin F, Yin L, Song X, Guo H, Liu J
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis.
Wei Z, Hang S, Wiredu Ocansey DK, Zhang Z, Wang B, Zhang X, Mao F
Journal of nanobiotechnology 2023 Jun 12;21(1):188
Journal of nanobiotechnology 2023 Jun 12;21(1):188
Sodium butyrate ameliorates diabetic retinopathy in mice via the regulation of gut microbiota and related short-chain fatty acids.
Huang Y, Wang Z, Ye B, Ma JH, Ji S, Sheng W, Ye S, Ou Y, Peng Y, Yang X, Chen J, Tang S
Journal of translational medicine 2023 Jul 7;21(1):451
Journal of translational medicine 2023 Jul 7;21(1):451
Open source board based acoustofluidic transwells for reversible disruption of the blood-brain barrier for therapeutic delivery.
Wang K, Sun C, Dumčius P, Zhang H, Liao H, Wu Z, Tian L, Peng W, Fu Y, Wei J, Cai M, Zhong Y, Li X, Yang X, Cui M
Biomaterials research 2023 Jul 15;27(1):69
Biomaterials research 2023 Jul 15;27(1):69
Astrocytes in the spinal cord contributed to acute stress-induced gastric damage via the gap junction protein CX43.
Wang Z, Shen Y, Huang C, Wang Y, Zhang X, Guo F, Weng R, Ma X, Sun H
Brain research 2023 Jul 15;1811:148395
Brain research 2023 Jul 15;1811:148395
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Wang CQ, Su Z, Dai CG, Song JL, Qian B
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation.
Lien WC, Zhou XR, Liang YJ, Ching CT, Wang CY, Lu FI, Chang HC, Lin FH, Wang HD
Bioengineering & translational medicine 2023 Jan;8(1):e10346
Bioengineering & translational medicine 2023 Jan;8(1):e10346
Apelin-13 prevents the effects of oxygen-glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT-mTOR signaling.
Zhang R, Wu F, Cheng B, Wang C, Bai B, Chen J
Experimental biology and medicine (Maywood, N.J.) 2023 Jan;248(2):146-156
Experimental biology and medicine (Maywood, N.J.) 2023 Jan;248(2):146-156
Polysaccharide-rich fractions from Enteromorpha prolifera improve hepatic steatosis and gut barrier integrity in high-fat diet-induced obese mice linking to modulation of gut microbiota.
Zou T, Xie F, Liang P, Chen J, Wang Z, Du M, You J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114034
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114034
Effects of thiacloprid exposure on microbiota-gut-liver axis: Multiomics mechanistic analysis in Japanese quails.
Han B, Li J, Li S, Liu Y, Zhang Z
Journal of hazardous materials 2023 Jan 15;442:130082
Journal of hazardous materials 2023 Jan 15;442:130082
Pulsatilla decoction improves DSS-induced colitis via modulation of fecal-bacteria-related short-chain fatty acids and intestinal barrier integrity.
Niu C, Hu XL, Yuan ZW, Xiao Y, Ji P, Wei YM, Hua YL
Journal of ethnopharmacology 2023 Jan 10;300:115741
Journal of ethnopharmacology 2023 Jan 10;300:115741
β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota.
Zhang X, Zhang Y, He Y, Zhu X, Ai Q, Shi Y
Journal of translational medicine 2023 Jan 10;21(1):14
Journal of translational medicine 2023 Jan 10;21(1):14
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Li B, Li W, Zheng M, Wang Y, Diao Y, Mou X, Liu J
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
PLK1 protects intestinal barrier function in sepsis: A translational research.
Cao YY, Li J, Chen Q, Qi YP, Xu QC, He JM, Wang Z, Lu WH
Cytokine 2023 Feb;162:156113
Cytokine 2023 Feb;162:156113
DHA-enriched phosphatidylserine alleviates high fat diet-induced jejunum injury in mice by modulating gut microbiota.
Tian S, Zhao Y, Qian L, Jiang S, Tang Y, Han T
Food & function 2023 Feb 6;14(3):1415-1429
Food & function 2023 Feb 6;14(3):1415-1429
Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1-CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice.
Yang Y, Ding T, Xiao G, Huang J, Luo D, Yue M, Su Y, Jiang S, Zeng J, Liu Y
Biomedicines 2023 Feb 5;11(2)
Biomedicines 2023 Feb 5;11(2)
Fecal microbiota transplantation attenuates Escherichia coli infected outgrowth by modulating the intestinal microbiome.
Wang Y, He Y, Liang Y, Liu H, Chen X, Kulyar MF, Shahzad A, Wei K, Li K
Microbial cell factories 2023 Feb 17;22(1):30
Microbial cell factories 2023 Feb 17;22(1):30
Disorders in the gut and liver are involved in depression contagion between isosexual post-stroke depression mice and the healthy cohabitors.
Wang H, Bin Wang, Pan MB, Jiang ST, Wang YC, Zhu Y, Zhang QC, Dong YF
Behavioural brain research 2023 Feb 15;439:114246
Behavioural brain research 2023 Feb 15;439:114246
Small molecule compound K-7174 attenuates neuropsychiatric manifestations in lupus-prone mice.
Fan Y, Liu X, Wu J, Ni J, Liang J, Hou Y, Dou H
Brain research 2023 Feb 15;1801:148203
Brain research 2023 Feb 15;1801:148203
Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.
Wang X, Huang S, Zhang M, Su Y, Pan Z, Liang J, Xie X, Wang Q, Chen J, Zhou L, Luo X
Journal of ethnopharmacology 2023 Feb 10;302(Pt B):115919
Journal of ethnopharmacology 2023 Feb 10;302(Pt B):115919
Effects of Houpo Mahuang Decoction on serum metabolism and TRPV1/Ca(2+)/TJs in asthma.
Zhou L, Hao M, Fan X, Lao Z, Li M, Shang E
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115873
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115873
Piceatannol and 3'-Hydroxypterostilbene Alleviate Inflammatory Bowel Disease by Maintaining Intestinal Epithelial Integrity and Regulating Gut Microbiota in Mice.
Lin WS, Chueh TL, Nagabhushanam K, Ho CT, Pan MH
Journal of agricultural and food chemistry 2023 Feb 1;71(4):1994-2005
Journal of agricultural and food chemistry 2023 Feb 1;71(4):1994-2005
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
Lin D, Sun Q, Liu Z, Pan J, Zhu J, Wang S, Jia S, Zheng M, Li X, Gong F
Free radical biology & medicine 2023 Feb 1;195:199-218
Free radical biology & medicine 2023 Feb 1;195:199-218
A new microphysiological system shows hypoxia primes human ISCs for interleukin-dependent rescue of stem cell activity.
Rivera KR, Bliton RJ, Burclaff J, Czerwinski MJ, Liu J, Trueblood JM, Hinesley CM, Breau KA, Joshi S, Pozdin VA, Yao M, Ziegler AL, Blikslager AT, Daniele MA, Magness ST
bioRxiv : the preprint server for biology 2023 Feb 1;
bioRxiv : the preprint server for biology 2023 Feb 1;
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Gao J, Wang Y, Jia Z, Xue J, Zhou T, Zu G
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Astragaloside IV ameliorate acute alcohol-induced liver injury in mice via modulating gut microbiota and regulating NLRP3/caspase-1 signaling pathway.
Wu S, Wen F, Zhong X, Du W, Chen M, Wang J
Annals of medicine 2023 Dec;55(1):2216942
Annals of medicine 2023 Dec;55(1):2216942
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Li J, Bai J, Song Z, Ji Y, Chen Z, Yang Y, Wu Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Assessment of intestinal status in MPL(W515L) mutant myeloproliferative neoplasms mice model.
Zhu S, Xu K, Li S, Yu X, Liu Y, Zhang Q, Zeng L, Xu K, Fu C
International immunopharmacology 2023 Dec;125(Pt A):111091
International immunopharmacology 2023 Dec;125(Pt A):111091
Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells.
He W, Wang J, Han M, Wang L, Li L, Zhang J, Chen S, Guo J, Zhai X, Yang J
Toxins 2023 Dec 4;15(12)
Toxins 2023 Dec 4;15(12)
Protocol for identifying physiologically relevant binding proteins of G-protein-coupled receptors.
Huang BX, Kim HY
STAR protocols 2023 Dec 15;4(4):102691
STAR protocols 2023 Dec 15;4(4):102691
A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS.
Johann L, Soldati S, Müller K, Lampe J, Marini F, Klein M, Schramm E, Ries N, Schelmbauer C, Palagi I, Karram K, Assmann JC, Khan MA, Wenzel J, Schmidt MH, Körbelin J, Schlüter D, van Loo G, Bopp T, Engelhardt B, Schwaninger M, Waisman A
The Journal of clinical investigation 2023 Dec 15;133(24)
The Journal of clinical investigation 2023 Dec 15;133(24)
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
Zhang ZT, Deng SM, Chen C, He QH, Peng XW, Liang QF, Zhuang GD, Wang SM, Tang D
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
PRMT7 can prevent neurovascular uncoupling, blood-brain barrier permeability, and mitochondrial dysfunction in repetitive and mild traumatic brain injury.
Acosta CH, Clemons GA, Citadin CT, Carr WC, Udo MSB, Tesic V, Sanicola HW, Freelin AH, Toms JB, Jordan JD, Guthikonda B, Rodgers KM, Wu CY, Lee RH, Lin HW
Experimental neurology 2023 Aug;366:114445
Experimental neurology 2023 Aug;366:114445
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Ge X, Wen H, Fei Y, Xue R, Cheng Z, Li Y, Cai K, Li L, Li M, Luo Z
Biomaterials 2023 Aug;299:122184
Biomaterials 2023 Aug;299:122184
Targeting formyl peptide receptor 1 with anteiso-C13-surfactin for neutrophil-dominant acute respiratory distress syndrome.
Yang SC, Wang YH, Ho CM, Tsai YF, Sung PJ, Lin TE, Hwang TL
British journal of pharmacology 2023 Aug;180(16):2120-2139
British journal of pharmacology 2023 Aug;180(16):2120-2139
Holothurian Wall Hydrolysate Ameliorates Cyclophosphamide-Induced Immunocompromised Mice via Regulating Immune Response and Improving Gut Microbiota.
Yan C, Qu H, Li X, Feng B
International journal of molecular sciences 2023 Aug 9;24(16)
International journal of molecular sciences 2023 Aug 9;24(16)
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
Hu J, Ding R, Liu S, Wang J, Li J, Shang Y
iScience 2023 Aug 18;26(8):107503
iScience 2023 Aug 18;26(8):107503
SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc.
Jiang T, Qin T, Gao P, Tao Z, Wang X, Wu M, Gu J, Chu B, Zheng Z, Yi J, Xu T, Huang Y, Liu H, Zhao S, Ren Y, Chen J, Yin G
Redox biology 2023 Apr;60:102615
Redox biology 2023 Apr;60:102615
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice.
Wang S, Liu J, Cheng D, Ren L, Zheng L, Chen F, Zeng T
Toxicology 2023 Apr;488:153487
Toxicology 2023 Apr;488:153487
Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of ADAM17.
Chan YJ, Hsiao G, Wan WN, Yang TM, Tsai CH, Kang JJ, Lee YC, Fang TC, Cheng YW, Li CH
Fluids and barriers of the CNS 2023 Apr 24;20(1):31
Fluids and barriers of the CNS 2023 Apr 24;20(1):31
Interaction between GPR110 (ADGRF1) and tight junction protein occludin implicated in blood-brain barrier permeability.
Huang BX, Chen H, Joo Y, Kwon HS, Fu C, Spector AA, Kim HY
iScience 2023 Apr 21;26(4):106550
iScience 2023 Apr 21;26(4):106550
Ginkgo biloba Extract Preventively Intervenes in Citrobacter Rodentium-Induced Colitis in Mice.
Chen T, Chen Y, Li K, Chen Z, Zhao Q, Fan Y, Liu Y, Zhang S, Hao Z
Nutrients 2023 Apr 21;15(8)
Nutrients 2023 Apr 21;15(8)
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Yang B, Xiong Z, Lin M, Yang Y, Chen Y, Zeng J, Jia X, Feng L
International journal of biological macromolecules 2023 Apr 15;234:123767
International journal of biological macromolecules 2023 Apr 15;234:123767
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Li J, Bai J, Si X, Jia H, Wu Z
Chemico-biological interactions 2023 Apr 1;374:110386
Chemico-biological interactions 2023 Apr 1;374:110386
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Yang Y, Zheng S, Chu H, Du C, Chen M, Emran MY, Chen J, Yang F, Tian L
Toxins 2023 Apr 1;15(4)
Toxins 2023 Apr 1;15(4)
Pterostilbene attenuates intestinal epithelial barrier loss induced by high loading intensity of exercise.
Zhang L, Tian G, Huang L, Zhou M, Zhu J, Yi L, Mi M
Frontiers in nutrition 2022;9:965180
Frontiers in nutrition 2022;9:965180
Probiotic Lactobacillus rhamnosus GR-1 supplementation attenuates Pb-induced learning and memory deficits by reshaping the gut microbiota.
Gu X, Bi N, Wang T, Huang C, Wang R, Xu Y, Wang HL
Frontiers in nutrition 2022;9:934118
Frontiers in nutrition 2022;9:934118
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Li P, Li M, Song Y, Huang X, Wu T, Xu ZZ, Lu H
Frontiers in nutrition 2022;9:832848
Frontiers in nutrition 2022;9:832848
Effects of Lipolysis-Stimulated Lipoprotein Receptor on Tight Junctions of Pancreatic Ductal Epithelial Cells in Hypertriglyceridemic Acute Pancreatitis.
Wang J, Qin M, Wu Q, Yang H, Wei B, Xie J, Qin Y, Liang Z, Huang J
BioMed research international 2022;2022:4234186
BioMed research international 2022;2022:4234186
Gut microbiota and butyrate contribute to nonalcoholic fatty liver disease in premenopause due to estrogen deficiency.
Liu L, Fu Q, Li T, Shao K, Zhu X, Cong Y, Zhao X
PloS one 2022;17(2):e0262855
PloS one 2022;17(2):e0262855
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Li B, Wang HY, Huang JH, Xu WF, Feng XJ, Xiong ZP, Dong YJ, Li LZ, He X, Wu HS, Zhang K, Su J, Yu QX, Jiang NH, Lv GY, Chen SH
Frontiers in pharmacology 2022;13:935714
Frontiers in pharmacology 2022;13:935714
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Wang Z, Yin L, Qi Y, Zhang J, Zhu H, Tang J
Frontiers in microbiology 2022;13:934786
Frontiers in microbiology 2022;13:934786
Tryptophan Supplementation Enhances Intestinal Health by Improving Gut Barrier Function, Alleviating Inflammation, and Modulating Intestinal Microbiome in Lipopolysaccharide-Challenged Piglets.
Liu G, Lu J, Sun W, Jia G, Zhao H, Chen X, Kim IH, Zhang R, Wang J
Frontiers in microbiology 2022;13:919431
Frontiers in microbiology 2022;13:919431
Effect of Tanshinone IIA on Gut Microbiome in Diabetes-Induced Cognitive Impairment.
Zheng Y, Zhou X, Wang C, Zhang J, Chang D, Liu W, Zhu M, Zhuang S, Shi H, Wang X, Chen Y, Cheng Z, Lin Y, Nan L, Sun Y, Min L, Liu J, Chen J, Zhang J, Huang M
Frontiers in pharmacology 2022;13:890444
Frontiers in pharmacology 2022;13:890444
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Zhang R, Xie L, Wu F, Xu J, Lu L, Cao L, Li L, Meng W, Zhang H, Shao C, Li X, Chen D
Frontiers in pharmacology 2022;13:828896
Frontiers in pharmacology 2022;13:828896
Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis.
Ghosh S, Moorthy B, Haribabu B, Jala VR
Frontiers in immunology 2022;13:1004603
Frontiers in immunology 2022;13:1004603
Liujunanwei decoction attenuates cisplatin-induced nausea and vomiting in a Rat-Pica model partially mediated by modulating the gut micsrobiome.
Chen D, Guo Y, Yang Y
Frontiers in cellular and infection microbiology 2022;12:876781
Frontiers in cellular and infection microbiology 2022;12:876781
Effects of Zhishi Daozhi Decoction on the intestinal flora of nonalcoholic fatty liver disease mice induced by a high-fat diet.
Bi CR, Sun JT, Du J, Chu LY, Li YJ, Jia XY, Liu Y, Zhang WP, Li YC, Liu YJ
Frontiers in cellular and infection microbiology 2022;12:1005318
Frontiers in cellular and infection microbiology 2022;12:1005318
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Li C, Pan Y, Tan Y, Wang Y, Sun X
Frontiers in cell and developmental biology 2022;10:896014
Frontiers in cell and developmental biology 2022;10:896014
GLP-1 receptor nitration contributes to loss of brain pericyte function in a mouse model of diabetes.
Bailey J, Coucha M, Bolduc DR, Burnett FN, Barrett AC, Ghaly M, Abdelsaid M
Diabetologia 2022 Sep;65(9):1541-1554
Diabetologia 2022 Sep;65(9):1541-1554
Dihydroartemisinin protects blood-brain barrier permeability during sepsis by inhibiting the transcription factor SNAI1.
Liu F, Liu J, Xiang H, Sun Z, Li Y, Li X, Liu Y, Liu J
Clinical and experimental pharmacology & physiology 2022 Sep;49(9):979-987
Clinical and experimental pharmacology & physiology 2022 Sep;49(9):979-987
Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis.
Li X, Li Q, Xiong B, Chen H, Wang X, Zhang D
Pharmacological research 2022 Sep;183:106368
Pharmacological research 2022 Sep;183:106368
BMP2 promotes lung adenocarcinoma metastasis through BMP receptor 2-mediated SMAD1/5 activation.
Wu CK, Wei MT, Wu HC, Wu CL, Wu CJ, Liaw H, Su WP
Scientific reports 2022 Sep 29;12(1):16310
Scientific reports 2022 Sep 29;12(1):16310
The Barrier-Enhancing Function of Soluble Yam (Dioscorea opposita Thunb.) Polysaccharides in Rat Intestinal Epithelial Cells as Affected by the Covalent Se Conjugation.
Wang ZX, Zhao XH
Nutrients 2022 Sep 23;14(19)
Nutrients 2022 Sep 23;14(19)
Probing the Potential Mechanism of Quercetin and Kaempferol against Heat Stress-Induced Sertoli Cell Injury: Through Integrating Network Pharmacology and Experimental Validation.
Liu DL, Liu SJ, Hu SQ, Chen YC, Guo J
International journal of molecular sciences 2022 Sep 22;23(19)
International journal of molecular sciences 2022 Sep 22;23(19)
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Siddiqui NZ, Rehman AU, Yousuf W, Khan AI, Farooqui NA, Zang S, Xin Y, Wang L
Gut pathogens 2022 Sep 17;14(1):39
Gut pathogens 2022 Sep 17;14(1):39
Effect and Mechanism of Pharmaceutical Excipients on Berberine to Alleviate Ulcerative Colitis via Regulating Gut Microbiota.
Wu C, Zheng T, Chen H, Zou P, Zhang M, Wang J, Li N, Zhang Y, Li Y, Dong Z
Molecules (Basel, Switzerland) 2022 Sep 15;27(18)
Molecules (Basel, Switzerland) 2022 Sep 15;27(18)
Phytic Acid Improves Hepatic Steatosis, Inflammation, and Oxidative Stress in High-Fat Diet (HFD)-Fed Mice by Modulating the Gut-Liver Axis.
Ran X, Hu G, He F, Li K, Li F, Xu D, Liu J, Fu S
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11401-11411
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11401-11411
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Zhang J, Li Q, Zhang X, Chen Y, Lu Y, Wang X, Zhang L, Wang T
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
Rice Protein Peptides Alleviate Dextran Sulfate Sodium-Induced Colitis via the Keap1-Nrf2 Signaling Pathway and Regulating Gut Microbiota.
Yang W, Huang Z, Xiong H, Wang J, Zhang H, Guo F, Wang C, Sun Y
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12469-12483
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12469-12483
Network Pharmacology Analysis and Experimental Validation of Kaempferol in the Treatment of Ischemic Stroke by Inhibiting Apoptosis and Regulating Neuroinflammation Involving Neutrophils.
Zhang SS, Liu M, Liu DN, Shang YF, Du GH, Wang YH
International journal of molecular sciences 2022 Oct 21;23(20)
International journal of molecular sciences 2022 Oct 21;23(20)
Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema.
Xue Y, Wang X, Wan B, Wang D, Li M, Cheng K, Luo Q, Wang D, Lu Y, Zhu L
Cell communication and signaling : CCS 2022 Oct 17;20(1):160
Cell communication and signaling : CCS 2022 Oct 17;20(1):160
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Tian Z, Zhang Y, Zheng Z, Zhang M, Zhang T, Jin J, Zhang X, Yao G, Kong D, Zhang C, Wang Z, Zhang Q
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Luteolin alleviates ulcerative colitis by restoring the balance of NCR(-)ILC3/NCR(+)ILC3 to repairing impaired intestinal barrier.
Xie X, Zhao M, Huang S, Li P, Chen P, Luo X, Wang Q, Pan Z, Li X, Chen J, Chen B, Zhou L
International immunopharmacology 2022 Nov;112:109251
International immunopharmacology 2022 Nov;112:109251
Natural borneol enhances the anti-cerebral ischaemia efficacy of formononetin in MCAO/R rats by promoting its delivery in the brain.
Li JY, Wang JX, Li QH, Li XF, Xiao JP, Li SS, Shen XP, Zhang WD, Shen YH
The Journal of pharmacy and pharmacology 2022 Nov 4;74(11):1598-1608
The Journal of pharmacy and pharmacology 2022 Nov 4;74(11):1598-1608
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Live and pasteurized Akkermansia muciniphila attenuate hyperuricemia in mice through modulating uric acid metabolism, inflammation, and gut microbiota.
Zhang L, Liu J, Jin T, Qin N, Ren X, Xia X
Food & function 2022 Nov 28;13(23):12412-12425
Food & function 2022 Nov 28;13(23):12412-12425
New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway.
Gu X, Miao Z, Wang Y, Yang Y, Yang T, Xu Y
BMC complementary medicine and therapies 2022 Nov 24;22(1):307
BMC complementary medicine and therapies 2022 Nov 24;22(1):307
Senegalia macrostachya seed polysaccharides attenuate inflammation-induced intestinal epithelial barrier dysfunction in a Caco-2 and RAW264.7 macrophage co-culture model by inhibiting the NF-κB/MLCK pathway.
Zongo AW, Zogona D, Youssef M, Ye S, Zhan F, Li J, Li B
Food & function 2022 Nov 14;13(22):11676-11689
Food & function 2022 Nov 14;13(22):11676-11689
DHA-enriched phosphatidylcholine from Clupea harengus roes regulates the gut-liver axis to ameliorate high-fat diet-induced non-alcoholic fatty liver disease.
Qian L, Tian S, Jiang S, Tang Y, Han T
Food & function 2022 Nov 14;13(22):11555-11567
Food & function 2022 Nov 14;13(22):11555-11567
Hippocampal Activated Microglia May Contribute to Blood-Brain Barrier Impairment and Cognitive Dysfunction in Post-Traumatic Stress Disorder-Like Rats.
Ni K, Zhu J, Xu X, Liu Y, Yang S, Huang Y, Xu R, Jiang L, Zhang J, Zhang W, Ma Z
Journal of molecular neuroscience : MN 2022 May;72(5):975-982
Journal of molecular neuroscience : MN 2022 May;72(5):975-982
A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair.
Lechuga S, Cartagena-Rivera AX, Khan A, Crawford BI, Narayanan V, Conway DE, Lehtimäki J, Lappalainen P, Rieder F, Longworth MS, Ivanov AI
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22290
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 May;36(5):e22290
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Yang G, Cao Y, Wang P, Mei L, Chen J, Lu W
The Journal of surgical research 2022 May;273:247-254
The Journal of surgical research 2022 May;273:247-254
Galactooligosaccharides as a protective agent for intestinal barrier and its regulatory functions for intestinal microbiota.
Wang G, Wang H, Jin Y, Xiao Z, Umar Yaqoob M, Lin Y, Chen H, Wang M
Food research international (Ottawa, Ont.) 2022 May;155:111003
Food research international (Ottawa, Ont.) 2022 May;155:111003
Effect of dendrobium mixture in alleviating diabetic cognitive impairment associated with regulating gut microbiota.
Zheng Y, Zhou X, Wang C, Zhang J, Chang D, Zhuang S, Xu W, Chen Y, Wang X, Nan L, Sun Y, Lin X, Lin W, He C, Dai L, Zhang J, Chen J, Shi H, Huang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112891
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112891
Dietary Alpha-Ketoglutarate Partially Abolishes Adverse Changes in the Small Intestine after Gastric Bypass Surgery in a Rat Model.
Iwaniak P, Tomaszewska E, Muszyński S, Marszałek-Grabska M, Pierzynowski SG, Dobrowolski P
Nutrients 2022 May 14;14(10)
Nutrients 2022 May 14;14(10)
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
Li J, Li Y, Liu P, Wang X, Ma Y, Zhong Q, Yang Q
Journal of virology 2022 May 11;96(9):e0038022
Journal of virology 2022 May 11;96(9):e0038022
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Ren X, Xing Y, He L, Xiu Z, Yang L, Han A, Jia Q, Dong Y
Journal of ethnopharmacology 2022 May 10;289:115029
Journal of ethnopharmacology 2022 May 10;289:115029
Dietary ferulic acid and vanillic acid on inflammation, gut barrier function and growth performance in lipopolysaccharide-challenged piglets.
Hu R, Wu S, Li B, Tan J, Yan J, Wang Y, Tang Z, Liu M, Fu C, Zhang H, He J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):144-152
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):144-152
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
Tan C, Fan H, Ding J, Han C, Guan Y, Zhu F, Wu H, Liu Y, Zhang W, Hou X, Tan S, Tang Q
Materials today. Bio 2022 Mar;14:100246
Materials today. Bio 2022 Mar;14:100246
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Du L, Hao YM, Yang YH, Zheng Y, Wu ZJ, Zhou MQ, Wang BZ, Wang YM, Wu H, Su GH
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2911-2922
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2911-2922
α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates DSS-induced intestinal colitis by improving intestinal mucosal barrier function.
Ye Z, Zhu Y, Tang N, Zhao X, Jiang J, Ma J, Zhang H
Molecular medicine (Cambridge, Mass.) 2022 Jun 3;28(1):59
Molecular medicine (Cambridge, Mass.) 2022 Jun 3;28(1):59
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Tian S, Wang J, Gao R, Wang J, Zhu W
Journal of animal science and biotechnology 2022 Jun 3;13(1):70
Journal of animal science and biotechnology 2022 Jun 3;13(1):70
Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis.
Ding Q, Cao F, Lai S, Zhuge H, Chang K, Valencak TG, Liu J, Li S, Ren D
Food research international (Ottawa, Ont.) 2022 Jul;157:111259
Food research international (Ottawa, Ont.) 2022 Jul;157:111259
Protective role of casuarinin from Melastoma malabathricum against a mouse model of 5-fluorouracil-induced intestinal mucositis: Impact on inflammation and gut microbiota dysbiosis.
Chen KJ, Huang YL, Kuo LM, Chen YT, Hung CF, Hsieh PW
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154092
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154092
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Tao W, Wang G, Pei X, Sun W, Wang M
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Effect of Houpo-Mahuang Decoction on aggravated asthma induced by cigarette smoke and the expression of TRPA1 and tight junctions in mice.
Sun YB, Ni Y, Fan XS, Zhou LP, Yue QF, Shang EX
Journal of ethnopharmacology 2022 Jul 15;293:115217
Journal of ethnopharmacology 2022 Jul 15;293:115217
Selenium exerts protective effects against heat stress-induced barrier disruption and inflammation response in jejunum of growing pigs.
He Y, Liu Y, Tang J, Jia G, Liu G, Tian G, Chen X, Cai J, Kang B, Zhao H
Journal of the science of food and agriculture 2022 Jan 30;102(2):496-504
Journal of the science of food and agriculture 2022 Jan 30;102(2):496-504
Gualou Xiebai Decoction ameliorates increased Caco-2 monolayer permeability induced by bile acids via tight junction regulation, oxidative stress suppression and apoptosis reduction.
Su J, He Z, Yu Y, Lu M, Wu Z, Zhang D
Journal of bioenergetics and biomembranes 2022 Feb;54(1):45-57
Journal of bioenergetics and biomembranes 2022 Feb;54(1):45-57
Effects of Exopolysaccharides from Lactiplantibacillus plantarum JLAU103 on Intestinal Immune Response, Oxidative Stress, and Microbial Communities in Cyclophosphamide-Induced Immunosuppressed Mice.
Wang J, Li M, Gao Y, Li H, Fang L, Liu C, Liu X, Min W
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2197-2210
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2197-2210
Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway.
Wang N, Feng BN, Hu B, Cheng YL, Guo YH, Qian H
Food & function 2022 Feb 21;13(4):2019-2032
Food & function 2022 Feb 21;13(4):2019-2032
Decreased ZO1 expression causes loss of time-dependent tight junction function in the liver of ob/ob mice.
Tsurudome Y, Morita N, Horiguchi M, Ushijima K
Molecular biology reports 2022 Dec;49(12):11881-11890
Molecular biology reports 2022 Dec;49(12):11881-11890
Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut-lung axis.
Jeyanathan M, Vaseghi-Shanjani M, Afkhami S, Grondin JA, Kang A, D'Agostino MR, Yao Y, Jain S, Zganiacz A, Kroezen Z, Shanmuganathan M, Singh R, Dvorkin-Gheva A, Britz-McKibbin P, Khan WI, Xing Z
Nature immunology 2022 Dec;23(12):1687-1702
Nature immunology 2022 Dec;23(12):1687-1702
Effects of betaine on viability, apoptosis, function protein expression and oxidative status in heat-stressed IEC-6 cells.
Sun S, Yin Q, Li B, Deng Y, Li J, Xiong Y, Shaojun H
Journal of thermal biology 2022 Dec;110:103348
Journal of thermal biology 2022 Dec;110:103348
Huang Qin Decoction inhibits the initiation of experimental colitis associated carcinogenesis by controlling the PAD4 dependent NETs.
Pan Z, Xie X, Chen Y, Pan S, Wu Z, Yang C, Liang J, Zhang M, Wang Q, Chen J, Zhou L, Luo X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154454
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154454
Dahuang Mudan decoction repairs intestinal barrier in chronic colitic mice by regulating the function of ILC3.
Huang S, Wang X, Xie X, Su Y, Pan Z, Li Y, Liang J, Zhang M, Pan S, Xu B, Li L, Chen J, Luo X, Zhou L
Journal of ethnopharmacology 2022 Dec 5;299:115652
Journal of ethnopharmacology 2022 Dec 5;299:115652
Glutathione Protects against Paraquat-Induced Oxidative Stress by Regulating Intestinal Barrier, Antioxidant Capacity, and CAR Signaling Pathway in Weaned Piglets.
Xiang X, Wang H, Zhou W, Wang C, Guan P, Xu G, Zhao Q, He L, Yin Y, Li T
Nutrients 2022 Dec 30;15(1)
Nutrients 2022 Dec 30;15(1)
Effect of ginsenoside compound K on alleviating colitis via modulating gut microbiota.
Wang L, Shao L, Chen MY, Wang L, Zhang W, Tan FB, Huang WH
Chinese medicine 2022 Dec 28;17(1):146
Chinese medicine 2022 Dec 28;17(1):146
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Wu Y, Bao W, Ren J, Li C, Chen M, Zhang D, Zhu A
Genes 2022 Dec 27;14(1)
Genes 2022 Dec 27;14(1)
Efficacy and Mechanism of Quercetin in the Treatment of Experimental Colitis Using Network Pharmacology Analysis.
Zhang Q, Wen F, Sun F, Xu Z, Liu Y, Tao C, Sun F, Jiang M, Yang M, Yao J
Molecules (Basel, Switzerland) 2022 Dec 24;28(1)
Molecules (Basel, Switzerland) 2022 Dec 24;28(1)
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Wang W, Jiang S, Xu C, Tang L, Liang Y, Zhao Y, Zhu G
Microbiology spectrum 2022 Dec 21;10(6):e0324222
Microbiology spectrum 2022 Dec 21;10(6):e0324222
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Zhao N, Yang Y, Chen C, Jing T, Hu Y, Xu H, Wang S, He Y, Liu E, Cui J
Food & function 2022 Dec 13;13(24):12814-12826
Food & function 2022 Dec 13;13(24):12814-12826
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Ge X, He Z, Cao C, Xue T, Jing J, Ma R, Zhao W, Liu L, Jueraitetibaike K, Ma J, Feng Y, Qian Z, Zou Z, Chen L, Fu C, Song N, Yao B
Redox biology 2022 Aug;54:102380
Redox biology 2022 Aug;54:102380
Chitosan-modified Phellinus igniarius polysaccharide PLGA nanoparticles ameliorated inflammatory bowel disease.
Bai X, Feng Z, Peng S, Zhu T, Jiao L, Mao N, Gu P, Liu Z, Yang Y, Wang D
Biomaterials advances 2022 Aug;139:213002
Biomaterials advances 2022 Aug;139:213002
Protective effect of surface-layer proteins from four Lactobacillus strains on tumor necrosis factor-α-induced intestinal barrier dysfunction.
Zhang J, Li Q, Wu L, Xu S, Lu R
Journal of the science of food and agriculture 2022 Aug 30;102(11):4446-4453
Journal of the science of food and agriculture 2022 Aug 30;102(11):4446-4453
Neohesperidin Dihydrochalcone Ameliorates High-Fat Diet-Induced Glycolipid Metabolism Disorder in Rats.
Xiao Y, Su D, Hu X, Yang G, Shan Y
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9421-9431
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9421-9431
Urolithin A attenuates arsenic-induced gut barrier dysfunction.
Ghosh S, Banerjee M, Haribabu B, Jala VR
Archives of toxicology 2022 Apr;96(4):987-1007
Archives of toxicology 2022 Apr;96(4):987-1007
P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer.
Naydenov NG, Lechuga S, Zalavadia A, Mukherjee PK, Gordon IO, Skvasik D, Vidovic P, Huang E, Rieder F, Ivanov AI
Cells 2022 Apr 27;11(9)
Cells 2022 Apr 27;11(9)
EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.
Fang J, Zhang Z, Cheng Y, Yang H, Zhang H, Xue Z, Lu S, Dong Y, Song C, Zhang X, Zhou Y
Food & function 2022 Apr 20;13(8):4399-4420
Food & function 2022 Apr 20;13(8):4399-4420
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Chen L, Huang X, Wang L, Wang C, Tang X, Gu M, Jing J, Ma R, Ge X, Yao B
Frontiers in cell and developmental biology 2021;9:648578
Frontiers in cell and developmental biology 2021;9:648578
Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota.
Zhou X, Lu J, Wei K, Wei J, Tian P, Yue M, Wang Y, Hong D, Li F, Wang B, Chen T, Fang X
Oxidative medicine and cellular longevity 2021;2021:9424582
Oxidative medicine and cellular longevity 2021;2021:9424582
Chlorogenic Acid Alleviates Colon Mucosal Damage Induced by a High-Fat Diet via Gut Microflora Adjustment to Increase Short-Chain Fatty Acid Accumulation in Rats.
Xie MG, Fei YQ, Wang Y, Wang WY, Wang Z
Oxidative medicine and cellular longevity 2021;2021:3456542
Oxidative medicine and cellular longevity 2021;2021:3456542
Binding and neutralization of C. difficile toxins A and B by purified clinoptilolite-tuff.
Ranftler C, Nagl D, Sparer A, Röhrich A, Freissmuth M, El-Kasaby A, Nasrollahi Shirazi S, Koban F, Tschegg C, Nizet S
PloS one 2021;16(5):e0252211
PloS one 2021;16(5):e0252211
Evaluation of the Anti-Aging Effects of a Probiotic Combination Isolated From Centenarians in a SAMP8 Mouse Model.
Fang X, Yue M, Wei J, Wang Y, Hong D, Wang B, Zhou X, Chen T
Frontiers in immunology 2021;12:792746
Frontiers in immunology 2021;12:792746
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
He Y, Chen J, Zhang Q, Zhang J, Wang L, Chen X, Molenaar AJ, Sun X
Frontiers in plant science 2021;12:673774
Frontiers in plant science 2021;12:673774
Fenretinide Improves Intestinal Barrier Function and Mitigates Alcohol Liver Disease.
Tang XH, Melis M, Mai K, Gudas LJ, Trasino SE
Frontiers in pharmacology 2021;12:630557
Frontiers in pharmacology 2021;12:630557
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Qi R, Zhang Z, Wang J, Qiu X, Wang Q, Yang F, Huang J, Liu Z
Frontiers in microbiology 2021;12:623673
Frontiers in microbiology 2021;12:623673
Diallyl Disulfide (DADS) Ameliorates Intestinal Candida albicans Infection by Modulating the Gut microbiota and Metabolites and Providing Intestinal Protection in Mice.
Hu W, Huang L, Zhou Z, Yin L, Tang J
Frontiers in cellular and infection microbiology 2021;11:743454
Frontiers in cellular and infection microbiology 2021;11:743454
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Qin Q, Chen Y, Li Y, Wei J, Zhou X, Le F, Hu H, Chen T
Frontiers in cellular and infection microbiology 2021;11:719542
Frontiers in cellular and infection microbiology 2021;11:719542
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 Sep;27(9):1048-1063
CNS neuroscience & therapeutics 2021 Sep;27(9):1048-1063
Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon.
Guo C, Guo D, Fang L, Sang T, Wu J, Guo C, Wang Y, Wang Y, Chen C, Chen J, Chen R, Wang X
Carbohydrate polymers 2021 Sep 1;267:118231
Carbohydrate polymers 2021 Sep 1;267:118231
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
Xun W, Fu Q, Shi L, Cao T, Jiang H, Ma Z
International immunopharmacology 2021 Oct;99:107989
International immunopharmacology 2021 Oct;99:107989
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Xu SY, Bian HJ, Shu S, Xia SN, Gu Y, Zhang MJ, Xu Y, Cao X
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
Sucralose enhances the susceptibility to dextran sulfate sodium (DSS) induced colitis in mice with changes in gut microbiota.
Guo M, Liu X, Tan Y, Kang F, Zhu X, Fan X, Wang C, Wang R, Liu Y, Qin X, Jiang M, Wang X
Food & function 2021 Oct 4;12(19):9380-9390
Food & function 2021 Oct 4;12(19):9380-9390
Influences of Xylitol Consumption at Different Dosages on Intestinal Tissues and Gut Microbiota in Rats.
Zuo QL, Cai X, Zheng XY, Chen DS, Li M, Liu ZQ, Chen KQ, Han FF, Zhu X
Journal of agricultural and food chemistry 2021 Oct 13;69(40):12002-12011
Journal of agricultural and food chemistry 2021 Oct 13;69(40):12002-12011
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Deng S, Wu D, Li L, Li J, Xu Y
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p.
Liu H, Liang J, Zhong Y, Xiao G, Efferth T, Georgiev MI, Vargas-De-La-Cruz C, Bajpai VK, Caprioli G, Liu J, Lin J, Wu H, Peng L, Li Y, Ma L, Xiao J, Wang Q
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13510-13523
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Wei R, Liu X, Wang Y, Dong J, Wu F, Mackenzie GG, Su Z
Food & function 2021 Nov 15;12(22):11671-11685
Food & function 2021 Nov 15;12(22):11671-11685
Rho-kinase inhibitor hydroxyfasudil protects against HIV-1 Tat-induced dysfunction of tight junction and neprilysin/Aβ transfer receptor expression in mouse brain microvessels.
Chen Q, Wu Y, Yu Y, Wei J, Huang W
Molecular and cellular biochemistry 2021 May;476(5):2159-2170
Molecular and cellular biochemistry 2021 May;476(5):2159-2170
Alterations in the gut microbiota and metabolic profiles coincide with intestinal damage in mice with a bloodborne Candida albicans infection.
Hu W, Xu D, Zhou Z, Zhu J, Wang D, Tang J
Microbial pathogenesis 2021 May;154:104826
Microbial pathogenesis 2021 May;154:104826
Effects of Qing Hua Chang Yin on lipopolysaccharide‑induced intestinal epithelial tight junction injury in Caco‑2 cells.
Fang W, Zhao P, Shen A, Liu L, Chen H, Chen Y, Peng J, Sferra TJ, Sankararaman S, Luo Y, Ke X
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Suppression of obesity and inflammation by polysaccharide from sporoderm-broken spore of Ganoderma lucidum via gut microbiota regulation.
Sang T, Guo C, Guo D, Wu J, Wang Y, Wang Y, Chen J, Chen C, Wu K, Na K, Li K, Fang L, Guo C, Wang X
Carbohydrate polymers 2021 Mar 15;256:117594
Carbohydrate polymers 2021 Mar 15;256:117594
Oral delivery of staphylococcal nuclease ameliorates DSS induced ulcerative colitis in mice via degrading intestinal neutrophil extracellular traps.
Dong W, Liu D, Zhang T, You Q, Huang F, Wu J
Ecotoxicology and environmental safety 2021 Jun 1;215:112161
Ecotoxicology and environmental safety 2021 Jun 1;215:112161
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Liu FY, Wen J, Hou J, Zhang SQ, Sun CB, Zhou LC, Yin W, Pang WL, Wang C, Ying Y, Han SS, Yan JY, Li CX, Yuan JL, Xing HJ, Yang ZS
International immunopharmacology 2021 Jul;96:107758
International immunopharmacology 2021 Jul;96:107758
Effects of cigarette smoke on the aggravation of ovalbumin-induced asthma and the expressions of TRPA1 and tight junctions in mice.
Sun YB, Liu M, Fan XS, Zhou LP, Li MW, Hu FY, Yue QF, Zhang YM
Molecular immunology 2021 Jul;135:62-72
Molecular immunology 2021 Jul;135:62-72
TNF-α released from retinal Müller cells aggravates retinal pigment epithelium cell apoptosis by upregulating mitophagy during diabetic retinopathy.
Liu Y, Li L, Pan N, Gu J, Qiu Z, Cao G, Dou Y, Dong L, Shuai J, Sang A
Biochemical and biophysical research communications 2021 Jul 5;561:143-150
Biochemical and biophysical research communications 2021 Jul 5;561:143-150
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Cao YY, Wang Z, Wang ZH, Jiang XG, Lu WH
International immunopharmacology 2021 Jan;90:107218
International immunopharmacology 2021 Jan;90:107218
Xinhuang Tablets Improve Intestinal Barrier Function via Regulating Epithelial Tight Junctions in Dextran Sulfate Sodium-Induced Ulcerative Colitis Mice.
Wu M, Shen A, Chen Y, Liu L, Li L, Sankararaman S, Chen H, Guan B, Zhan Z, Nan S, Sferra TJ, Peng J
Journal of medicinal food 2021 Jan;24(1):33-39
Journal of medicinal food 2021 Jan;24(1):33-39
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Jia Z, Bao K, Wei P, Yu X, Zhang Y, Wang X, Wang X, Yao L, Li L, Wu P, Yuan W, Wang S, Zheng J, Hua Y, Hong M
Mucosal immunology 2021 Jan;14(1):125-134
Mucosal immunology 2021 Jan;14(1):125-134
Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation.
Chan YJ, Liao PL, Tsai CH, Cheng YW, Lin FL, Ho JD, Chen CY, Li CH
Particle and fibre toxicology 2021 Jan 9;18(1):4
Particle and fibre toxicology 2021 Jan 9;18(1):4
Polystyrene microplastics induced male reproductive toxicity in mice.
Jin H, Ma T, Sha X, Liu Z, Zhou Y, Meng X, Chen Y, Han X, Ding J
Journal of hazardous materials 2021 Jan 5;401:123430
Journal of hazardous materials 2021 Jan 5;401:123430
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, Huang R, Yin Y
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Xianglian Pill ameliorates antibiotic-associated diarrhea by restoring intestinal microbiota and attenuating mucosal damage.
Yang L, Zhang Q, Huang J, Liu D, Lan Y, Yuan L, Chen Q
Journal of ethnopharmacology 2021 Jan 10;264:113377
Journal of ethnopharmacology 2021 Jan 10;264:113377
Combination of Mesenchymal Stem Cell and Endothelial Progenitor Cell Infusion Accelerates Injured Intestinal Repair by Regulating Gut Microbiota after Hematopoietic Cell Transplantation.
Zhu S, Li H, Lv C, Liang J, Liu L, Zhang X, Xu K, Zeng L
Transplantation and cellular therapy 2021 Feb;27(2):152.e1-152.e9
Transplantation and cellular therapy 2021 Feb;27(2):152.e1-152.e9
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Ma J, Shah AM, Wang ZS, Hu R, Zou HW, Wang XY, Zhao SN, Kong XY
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Chen KJ, Chen YL, Ueng SH, Hwang TL, Kuo LM, Hsieh PW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Li J, Zhang L, Wu T, Li Y, Zhou X, Ruan Z
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Tocmo R, Le B, Heun A, van Pijkeren JP, Parkin K, Johnson JJ
Free radical biology & medicine 2021 Feb 1;163:102-115
Free radical biology & medicine 2021 Feb 1;163:102-115
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Chen Y, Zhang H, Ji S, Jia P, Chen Y, Li Y, Wang T
Free radical biology & medicine 2021 Dec;177:1-14
Free radical biology & medicine 2021 Dec;177:1-14
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Cao Q, Wei W, Wang H, Wang Z, Lv Y, Dai M, Tan C, Chen H, Wang X
Virulence 2021 Dec;12(1):2296-2313
Virulence 2021 Dec;12(1):2296-2313
Titanium dioxide nanoparticles perturb the blood-testis barrier via disruption of actin-based cell adhesive function.
Ni DQ, Ma DD, Hao SL, Yang WX, Kovacs T, Tan FQ
Aging 2021 Dec 14;13(23):25440-25452
Aging 2021 Dec 14;13(23):25440-25452
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Jiao-Yan Y, Qing-Qing L, Xi L, Mei Z, Ting S, Na H, Wei J, Rui-Tao Z, Peng Y, Qi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Chen Y, Jiang Z, Lei Z, Ping J, Su J
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Ma J, Shah AM, Wang Z, Hu R, Zou H, Wang X, Cao G, Peng Q, Xue B, Wang L, Zhao S, Kong X
PeerJ 2020;8:e9851
PeerJ 2020;8:e9851
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Yang F, Zhang Y, Zhu J, Wang J, Jiang Z, Zhao C, Yang Q, Huang Y, Yao W, Pang W, Han L, Zhou J
Frontiers in bioengineering and biotechnology 2020;8:647
Frontiers in bioengineering and biotechnology 2020;8:647
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
Increase of BACE1, Brain-Renal Risk Factor, Contributes to Kidney Damage in an Alzheimer's Disease Mouse Model.
Shi Y, Gao F, Yang X, Liu D, Han Q, Liu Z, Zhu H, Shen Y
Journal of Alzheimer's disease : JAD 2020;76(1):237-248
Journal of Alzheimer's disease : JAD 2020;76(1):237-248
Changes of Gut Microbiota and Its Correlation With Short Chain Fatty Acids and Bioamine in Piglets at the Early Growth Stage.
Qi R, Qiu X, Du L, Wang J, Wang Q, Huang J, Liu Z
Frontiers in veterinary science 2020;7:617259
Frontiers in veterinary science 2020;7:617259
Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.
Wang X, Bi X, Huang X, Wang B, Guo Q, Wu Z
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
Cancer biomarkers : section A of Disease markers 2020;28(1):101-110
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Liu DY, Lou WJ, Zhang DY, Sun SY
BioMed research international 2020;2020:8819195
BioMed research international 2020;2020:8819195
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Wang W, Zhong M, Yu T, Chen L, Shi L, Zong J, Wang S
Nutrition & metabolism 2020;17:27
Nutrition & metabolism 2020;17:27
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Chen L, Zhang L, Wang W, Qiu W, Liu L, Ning A, Cao J, Huang M, Zhong M
PloS one 2020;15(6):e0232972
PloS one 2020;15(6):e0232972
Isolation of Mouse Cerebral Microvasculature for Molecular and Single-Cell Analysis.
Paraiso HC, Wang X, Kuo PC, Furnas D, Scofield BA, Chang FL, Yen JH, Yu IC
Frontiers in cellular neuroscience 2020;14:84
Frontiers in cellular neuroscience 2020;14:84
Alpha-1 Antitrypsin Induces Epithelial-to-Mesenchymal Transition, Endothelial-to-Mesenchymal Transition, and Drug Resistance in Lung Cancer Cells.
Wu DM, Liu T, Deng SH, Han R, Zhang T, Li J, Xu Y
OncoTargets and therapy 2020;13:3751-3763
OncoTargets and therapy 2020;13:3751-3763
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
Hu R, He Z, Liu M, Tan J, Zhang H, Hou DX, He J, Wu S
Journal of animal science and biotechnology 2020;11:92
Journal of animal science and biotechnology 2020;11:92
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Zhang H, Chen Y, Chen Y, Ji S, Jia P, Li Y, Wang T
Journal of animal science and biotechnology 2020;11:52
Journal of animal science and biotechnology 2020;11:52
Dietary Copper Plays an Important Role in Maintaining Intestinal Barrier Integrity During Alcohol-Induced Liver Disease Through Regulation of the Intestinal HIF-1α Signaling Pathway and Oxidative Stress.
Lin H, Chen D, Du Q, Pan T, Tu H, Xu Y, Teng T, Tu J, Li J, Lin Z, Wang X, Xu L, Chen YP
Frontiers in physiology 2020;11:369
Frontiers in physiology 2020;11:369
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Ding F, Wu J, Liu C, Bian Q, Qiu W, Ma Q, Li X, Long M, Zou X, Chen J
Frontiers in pharmacology 2020;11:1069
Frontiers in pharmacology 2020;11:1069
Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting.
Ren L, Feng W, Shao J, Ma J, Xu M, Zhu BZ, Zheng N, Liu S
Theranostics 2020;10(14):6384-6398
Theranostics 2020;10(14):6384-6398
Sucralose Promotes Colitis-Associated Colorectal Cancer Risk in a Murine Model Along With Changes in Microbiota.
Li X, Liu Y, Wang Y, Li X, Liu X, Guo M, Tan Y, Qin X, Wang X, Jiang M
Frontiers in oncology 2020;10:710
Frontiers in oncology 2020;10:710
Salmonella Effector SpvB Disrupts Intestinal Epithelial Barrier Integrity for Bacterial Translocation.
Sun L, Yang S, Deng Q, Dong K, Li Y, Wu S, Huang R
Frontiers in cellular and infection microbiology 2020;10:606541
Frontiers in cellular and infection microbiology 2020;10:606541
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
Liu Y, Ma Y, Du B, Wang Y, Yang GY, Bi X
Molecular neurobiology 2020 Sep;57(9):3891-3901
Molecular neurobiology 2020 Sep;57(9):3891-3901
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, Zhang J, Jing W, Cong B, Ma C
Brain research bulletin 2020 Sep;162:73-83
Brain research bulletin 2020 Sep;162:73-83
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Furutama D, Matsuda S, Yamawaki Y, Hatano S, Okanobu A, Memida T, Oue H, Fujita T, Ouhara K, Kajiya M, Mizuno N, Kanematsu T, Tsuga K, Kurihara H
Brain sciences 2020 Sep 27;10(10)
Brain sciences 2020 Sep 27;10(10)
Interferon-β alleviates delayed tPA-induced adverse effects via modulation of MMP3/9 production in ischemic stroke.
Kuo PC, Weng WT, Scofield BA, Furnas D, Paraiso HC, Intriago AJ, Bosi KD, Yu IC, Yen JH
Blood advances 2020 Sep 22;4(18):4366-4381
Blood advances 2020 Sep 22;4(18):4366-4381
Claudin 1 inhibits cell migration and increases intercellular adhesion in triple-negative breast cancer cell line.
Geoffroy M, Kleinclauss A, Kuntz S, Grillier-Vuissoz I
Molecular biology reports 2020 Oct;47(10):7643-7653
Molecular biology reports 2020 Oct;47(10):7643-7653
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Yang Q, Luo L, Sun T, Yang L, Cheng LF, Wang Y, Liu QQ, Liu A, Liu HY, Zhao MG, Wu SX, Feng B
Psychopharmacology 2020 Oct;237(10):3201-3213
Psychopharmacology 2020 Oct;237(10):3201-3213
Dl-3-n-butylphthalide attenuates hypoxic-ischemic brain injury through inhibiting endoplasmic reticulum stress-induced cell apoptosis and alleviating blood-brain barrier disruption in newborn rats.
Fang M, Yuan J, Jiang S, Hu Y, Pan S, Zhu J, Fu X, Jiang H, Lin J, Li P, Lin Z
Brain research 2020 Nov 15;1747:147046
Brain research 2020 Nov 15;1747:147046
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Wu DM, Deng SH, Zhou J, Han R, Liu T, Zhang T, Li J, Chen JP, Xu Y
International journal of cancer 2020 May 1;146(9):2563-2575
International journal of cancer 2020 May 1;146(9):2563-2575
Assessment of oral ciprofloxacin impaired gut barrier integrity on gut bacteria in mice.
Zhu S, Li H, Liang J, Lv C, Zhao K, Niu M, Li Z, Zeng L, Xu K
International immunopharmacology 2020 Jun;83:106460
International immunopharmacology 2020 Jun;83:106460
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Yin J, Zhou C, Yang K, Ren Y, Qiu Y, Xu P, Xiao W, Yang H
Cell biology international 2020 Jun;44(6):1405-1414
Cell biology international 2020 Jun;44(6):1405-1414
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein‑related peptidase 4 and tight junction proteins in ameloblasts.
Gao J, Li X, Gao L, Chen H, Baras BH, Liu X, Liu H, Rana A, Gao M, Ruan J
International journal of molecular medicine 2020 Jul;46(1):179-190
International journal of molecular medicine 2020 Jul;46(1):179-190
Maternal Exposure to Di-n-butyl Phthalate Promotes the Formation of Testicular Tight Junctions through Downregulation of NF-κB/COX-2/PGE(2)/MMP-2 in Mouse Offspring.
Ma T, Zhou Y, Xia Y, Meng X, Jin H, Wang B, Chen Y, Qiu J, Wu J, Ding J, Han X, Li D
Environmental science & technology 2020 Jul 7;54(13):8245-8258
Environmental science & technology 2020 Jul 7;54(13):8245-8258
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, Wen S, Zhao D, Wu H, Chen J, Sun Y, Duan Z
Archives of microbiology 2020 Jan;202(1):161-169
Archives of microbiology 2020 Jan;202(1):161-169
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.
Sun D, Yang L, Cao H, Shen ZY, Song HL
Cell biology international 2020 Feb;44(2):549-559
Cell biology international 2020 Feb;44(2):549-559
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Tian M, Ma P, Zhang Y, Mi Y, Fan D
International immunopharmacology 2020 Aug;85:106645
International immunopharmacology 2020 Aug;85:106645
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia.
Li M, Li SC, Dou BK, Zou YX, Han HZ, Liu DX, Ke ZJ, Wang ZF
Acta pharmacologica Sinica 2020 Aug;41(8):1025-1032
Acta pharmacologica Sinica 2020 Aug;41(8):1025-1032
A Novel Pharmacological Approach to Enhance the Integrity and Accelerate Restitution of the Intestinal Epithelial Barrier.
Cao X, Sun L, Lechuga S, Naydenov NG, Feygin A, Ivanov AI
Inflammatory bowel diseases 2020 Aug 20;26(9):1340-1352
Inflammatory bowel diseases 2020 Aug 20;26(9):1340-1352
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Guo H, He J, Yang X, Zheng W, Yao W
Journal of thermal biology 2020 Apr;89:102539
Journal of thermal biology 2020 Apr;89:102539
Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke.
Zhang Y, Zhang X, Wei Q, Leng S, Li C, Han B, Bai Y, Zhang H, Yao H
Translational stroke research 2020 Apr;11(2):267-287
Translational stroke research 2020 Apr;11(2):267-287
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L
Theranostics 2019;9(17):5065-5084
Theranostics 2019;9(17):5065-5084
The Functional Role of Fecal Microbiota Transplantation on Dextran Sulfate Sodium-Induced Colitis in Mice.
He Y, Li X, Yu H, Ge Y, Liu Y, Qin X, Jiang M, Wang X
Frontiers in cellular and infection microbiology 2019;9:393
Frontiers in cellular and infection microbiology 2019;9:393
Puerarin prevents high-fat diet-induced obesity by enriching Akkermansia muciniphila in the gut microbiota of mice.
Wang L, Wu Y, Zhuang L, Chen X, Min H, Song S, Liang Q, Li AD, Gao Q
PloS one 2019;14(6):e0218490
PloS one 2019;14(6):e0218490
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
Hu L, Wu C, Zhang Z, Liu M, Maruthi Prasad E, Chen Y, Wang K
Frontiers in physiology 2019;10:908
Frontiers in physiology 2019;10:908
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, Gong Z, Zeng Q, Wei Y, Yang W, Zeng Z, He X, Huang SH, Cao H
Frontiers in microbiology 2019;10:477
Frontiers in microbiology 2019;10:477
Characterization of a Novel Diarrheagenic Strain of Proteus mirabilis Associated With Food Poisoning in China.
Gong Z, Shi X, Bai F, He X, Zhang H, Li Y, Wan Y, Lin Y, Qiu Y, Chen Q, Hu Q, Cao H
Frontiers in microbiology 2019;10:2810
Frontiers in microbiology 2019;10:2810
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Bao K, Yuan W, Zhou Y, Chen Y, Yu X, Wang X, Jia Z, Yu X, Wang X, Yao L, Wang S, Xu Y, Zhang Y, Zheng J, Hong M
Frontiers in pharmacology 2019;10:1698
Frontiers in pharmacology 2019;10:1698
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Nan D, Jin H, Deng J, Yu W, Liu R, Sun W, Huang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Luo L, Liu Y, Cai X, Wang Y, Xue J, Zhang J, Yang F
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Li X, Mao M, Zhang Y, Yu K, Zhu W
Biomolecules 2019 Sep 13;9(9)
Biomolecules 2019 Sep 13;9(9)
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
He F, Dai R, Zhou X, Li X, Song X, Yan H, Meng Q, Yang C, Lin Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109260
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
Ren MT, Gu ML, Zhou XX, Yu MS, Pan HH, Ji F, Ding CY
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
Cadmium regulates von Willebrand factor and occludin expression in glomerular endothelial cells of mice in a TNF-α-dependent manner.
Sun Z, Xie Q, Pan J, Niu N
Renal failure 2019 Nov;41(1):354-362
Renal failure 2019 Nov;41(1):354-362
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z
Toxicology letters 2019 Nov;316:109-118
Toxicology letters 2019 Nov;316:109-118
Intestinal epithelial PKM2 serves as a safeguard against experimental colitis via activating β-catenin signaling.
Sun X, Yao L, Liang H, Wang D, He Y, Wei Y, Ye L, Wang K, Li L, Chen J, Zhang CY, Xu G, Wang F, Zen K
Mucosal immunology 2019 Nov;12(6):1280-1290
Mucosal immunology 2019 Nov;12(6):1280-1290
The protective effect of selenium from heat stress-induced porcine small intestinal epithelial cell line (IPEC-J2) injury is associated with regulation expression of selenoproteins.
Tang J, Cao L, Jia G, Liu G, Chen X, Tian G, Cai J, Shang H, Zhao H
The British journal of nutrition 2019 Nov 28;122(10):1081-1090
The British journal of nutrition 2019 Nov 28;122(10):1081-1090
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Wang J, Zhang C, Guo C, Li X
International journal of molecular sciences 2019 Nov 15;20(22)
International journal of molecular sciences 2019 Nov 15;20(22)
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Xia Y, Chen S, Zhao Y, Chen S, Huang R, Zhu G, Yin Y, Ren W, Deng J
Food & function 2019 Nov 1;10(11):7509-7522
Food & function 2019 Nov 1;10(11):7509-7522
Bacterial β-glucuronidase alleviates dextran sulfate sodium-induced colitis in mice: A possible crucial new diagnostic and therapeutic target for inflammatory bowel disease.
He Y, Yu H, Ge Y, Li X, Jiang M, Liu Y, Li X, Wang Y, Guo M, Qin X, Wang X
Biochemical and biophysical research communications 2019 May 28;513(2):426-433
Biochemical and biophysical research communications 2019 May 28;513(2):426-433
Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions.
Zhu Z, Yu J, Lin W, Tang H, Zhang W, Lu B
Molecular medicine reports 2019 Jun;19(6):5177-5184
Molecular medicine reports 2019 Jun;19(6):5177-5184
Fasudil alleviates LPS-induced lung injury by restoring aquaporin 5 expression and inhibiting inflammation in lungs.
Wang JJ, Kong H, Xu J, Wang YL, Wang H, Xie WP
Journal of biomedical research 2019 Jun 4;33(3):156-163
Journal of biomedical research 2019 Jun 4;33(3):156-163
Newly synthesized claudins but not occludin are added to the basal side of the tight junction.
Van Itallie CM, Lidman KF, Tietgens AJ, Anderson JM
Molecular biology of the cell 2019 Jun 1;30(12):1406-1424
Molecular biology of the cell 2019 Jun 1;30(12):1406-1424
Propofol attenuated TNF-α-modulated occludin expression by inhibiting Hif-1α/ VEGF/ VEGFR-2/ ERK signaling pathway in hCMEC/D3 cells.
Zhang Y, Ding X, Miao C, Chen J
BMC anesthesiology 2019 Jul 9;19(1):127
BMC anesthesiology 2019 Jul 9;19(1):127
SET domain containing protein 5 (SETD5) enhances tumor cell invasion and is associated with a poor prognosis in non-small cell lung cancer patients.
Yu H, Sun J, Zhao C, Wang H, Liu Y, Xiong J, Chang J, Wang M, Wang W, Ye D, Zhou H, Yu T
BMC cancer 2019 Jul 25;19(1):736
BMC cancer 2019 Jul 25;19(1):736
KHDRBS3 regulates the permeability of blood-tumor barrier via cDENND4C/miR-577 axis.
Wu P, Gao Y, Shen S, Xue Y, Liu X, Ruan X, Shao L, Liu Y, Wang P
Cell death & disease 2019 Jul 11;10(7):536
Cell death & disease 2019 Jul 11;10(7):536
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, Jin L, Li S
Cellular signalling 2019 Jan;53:151-161
Cellular signalling 2019 Jan;53:151-161
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Cao W, Wang C, Chin Y, Chen X, Gao Y, Yuan S, Xue C, Wang Y, Tang Q
Food & function 2019 Jan 22;10(1):277-288
Food & function 2019 Jan 22;10(1):277-288
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Wang J, Tian S, Yu H, Wang J, Zhu W
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer.
Liao Z, Zhang H, Fan P, Huang Q, Dong K, Qi Y, Song J, Chen L, Liang H, Chen X, Zhang Z, Zhang B
International journal of oncology 2019 Feb;54(2):479-490
International journal of oncology 2019 Feb;54(2):479-490
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, Hu Y, Mortensen RM, Greenson JK, Cascalho M, Wobus CE, Colacino JA, Nunez G, Rui L, Shah YM
Nature communications 2019 Feb 8;10(1):660
Nature communications 2019 Feb 8;10(1):660
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
You M, Miao Z, Pan Y, Hu F
European journal of pharmacology 2019 Dec 15;865:172736
European journal of pharmacology 2019 Dec 15;865:172736
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
Xu J, Wei G, Wang J, Zhu J, Yu M, Zeng X, Wang H, Xie W, Kong H
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Li X, Dong M, Zhou J, Zhu D, Zhao J, Sheng W
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Huang Y, He J, Liang H, Hu K, Jiang S, Yang L, Mei S, Zhu X, Yu J, Kijlstra A, Yang P, Hou S
Frontiers in immunology 2018;9:1713
Frontiers in immunology 2018;9:1713
Effects of dietary supplementation with Lactobacillus acidophilus on the performance, intestinal physical barrier function, and the expression of NOD-like receptors in weaned piglets.
Wang S, Li H, Du C, Liu Q, Yang D, Chen L, Zhu Q, Wang Z
PeerJ 2018;6:e6060
PeerJ 2018;6:e6060
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Wang Y, Kim R, Gunasekara DB, Reed MI, DiSalvo M, Nguyen DL, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
Xiao Z, Liu L, Tao W, Pei X, Wang G, Wang M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
Probiotic Mixture Protects Dextran Sulfate Sodium-Induced Colitis by Altering Tight Junction Protein Expressions and Increasing Tregs.
Zhang Y, Zhao X, Zhu Y, Ma J, Ma H, Zhang H
Mediators of inflammation 2018;2018:9416391
Mediators of inflammation 2018;2018:9416391
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
Yu M, Wang Q, Ma Y, Li L, Yu K, Zhang Z, Chen G, Li X, Xiao W, Xu P, Yang H
International journal of biological sciences 2018;14(1):69-77
International journal of biological sciences 2018;14(1):69-77
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Jia Z, Wang X, Wang X, Wei P, Li L, Wu P, Hong M
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
Luo L, Zhou Z, Xue J, Wang Y, Zhang J, Cai X, Liu Y, Yang F
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Adegoke EO, Wang C, Machebe NS, Wang X, Wang H, Adeniran SO, Zhang H, Zheng P, Zhang G
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Adegoke EO, Wang X, Wang H, Wang C, Zhang H, Zhang G
Biological trace element research 2018 Oct;185(2):332-343
Biological trace element research 2018 Oct;185(2):332-343
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Liu WT, Lv YJ, Yang RC, Fu JY, Liu L, Wang H, Cao Q, Tan C, Chen HC, Wang XR
Journal of neuroinflammation 2018 Oct 19;15(1):291
Journal of neuroinflammation 2018 Oct 19;15(1):291
Mechanism of piR-DQ590027/MIR17HG regulating the permeability of glioma conditioned normal BBB.
Leng X, Ma J, Liu Y, Shen S, Yu H, Zheng J, Liu X, Liu L, Chen J, Zhao L, Ruan X, Xue Y
Journal of experimental & clinical cancer research : CR 2018 Oct 11;37(1):246
Journal of experimental & clinical cancer research : CR 2018 Oct 11;37(1):246
Arsenic induces autophagy in developmental mouse cerebral cortex and hippocampus by inhibiting PI3K/Akt/mTOR signaling pathway: involvement of blood-brain barrier's tight junction proteins.
Manthari RK, Tikka C, Ommati MM, Niu R, Sun Z, Wang J, Zhang J, Wang J
Archives of toxicology 2018 Nov;92(11):3255-3275
Archives of toxicology 2018 Nov;92(11):3255-3275
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Wu YY, Li TM, Zang LQ, Liu B, Wang GX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
Nasal epithelial barrier disruption by particulate matter ≤2.5 μm via tight junction protein degradation.
Zhao R, Guo Z, Zhang R, Deng C, Xu J, Dong W, Hong Z, Yu H, Situ H, Liu C, Zhuang G
Journal of applied toxicology : JAT 2018 May;38(5):678-687
Journal of applied toxicology : JAT 2018 May;38(5):678-687
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Liu Z, Li L, Chen W, Wang Q, Xiao W, Ma Y, Sheng B, Li X, Sun L, Yu M, Yang H
International journal of molecular medicine 2018 Mar;41(3):1560-1572
International journal of molecular medicine 2018 Mar;41(3):1560-1572
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
Zhang X, Jiang G, Wu J, Zhou H, Zhang Y, Miao Y, Feng Y, Yu J
Oncology letters 2018 Mar;15(3):3806-3813
Oncology letters 2018 Mar;15(3):3806-3813
PIWIL1/piRNA-DQ593109 Regulates the Permeability of the Blood-Tumor Barrier via the MEG3/miR-330-5p/RUNX3 Axis.
Shen S, Yu H, Liu X, Liu Y, Zheng J, Wang P, Gong W, Chen J, Zhao L, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:412-425
Molecular therapy. Nucleic acids 2018 Mar 2;10:412-425
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
Lu M, Wu J, Hao ZW, Shang YK, Xu J, Nan G, Li X, Chen ZN, Bian H
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)
Nutrients 2018 Jul 31;10(8)
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Zou Y, Ma L, Zhao Y, Zhang S, Zhou C, Cai Y
International journal of molecular medicine 2018 Jan;41(1):430-438
International journal of molecular medicine 2018 Jan;41(1):430-438
Metformin protects against intestinal barrier dysfunction via AMPKα1-dependent inhibition of JNK signalling activation.
Deng J, Zeng L, Lai X, Li J, Liu L, Lin Q, Chen Y
Journal of cellular and molecular medicine 2018 Jan;22(1):546-557
Journal of cellular and molecular medicine 2018 Jan;22(1):546-557
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Zhang DD, Jin C, Zhang YT, Gan XD, Zou MJ, Wang YY, Fu WL, Xu T, Xing WW, Xia WR, Xu DG
Journal of neuroinflammation 2018 Jan 15;15(1):16
Journal of neuroinflammation 2018 Jan 15;15(1):16
Role of serotonin in the intestinal mucosal epithelium barrier in weaning mice undergoing stress-induced diarrhea.
Dong Y, Wang Z, Qin Z, Cao J, Chen Y
Journal of molecular histology 2018 Feb;49(1):85-97
Journal of molecular histology 2018 Feb;49(1):85-97
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
Yang S, Jin H, Zhao Z
Neurological research 2018 Feb;40(2):117-121
Neurological research 2018 Feb;40(2):117-121
MARCKS-related protein regulates cytoskeletal organization at cell-cell and cell-substrate contacts in epithelial cells.
Van Itallie CM, Tietgens AJ, Aponte A, Gucek M, Cartagena-Rivera AX, Chadwick RS, Anderson JM
Journal of cell science 2018 Feb 2;131(3)
Journal of cell science 2018 Feb 2;131(3)
Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage.
Adegoke EO, Xue W, Machebe NS, Adeniran SO, Hao W, Chen W, Han Z, Guixue Z, Peng Z
Ecotoxicology and environmental safety 2018 Dec 30;166:165-175
Ecotoxicology and environmental safety 2018 Dec 30;166:165-175
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Wang S, Xie T, Sun S, Wang K, Liu B, Wu X, Ding W
Scientific reports 2018 Dec 12;8(1):17788
Scientific reports 2018 Dec 12;8(1):17788
Deficiency in intestinal epithelial O-GlcNAcylation predisposes to gut inflammation.
Zhao M, Xiong X, Ren K, Xu B, Cheng M, Sahu C, Wu K, Nie Y, Huang Z, Blumberg RS, Han X, Ruan HB
EMBO molecular medicine 2018 Aug;10(8)
EMBO molecular medicine 2018 Aug;10(8)
Arsenic-Induced Autophagy in the Developing Mouse Cerebellum: Involvement of the Blood-Brain Barrier's Tight-Junction Proteins and the PI3K-Akt-mTOR Signaling Pathway.
Manthari RK, Tikka C, Ommati MM, Niu R, Sun Z, Wang J, Zhang J, Wang J
Journal of agricultural and food chemistry 2018 Aug 15;66(32):8602-8614
Journal of agricultural and food chemistry 2018 Aug 15;66(32):8602-8614
Endoplasmic Reticulum Stress Mediates Methamphetamine-Induced Blood-Brain Barrier Damage.
Qie X, Wen D, Guo H, Xu G, Liu S, Shen Q, Liu Y, Zhang W, Cong B, Ma C
Frontiers in pharmacology 2017;8:639
Frontiers in pharmacology 2017;8:639
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Li L, Wang N, Jin Q, Wu Q, Liu Y, Wang Y
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity.
Zhang QY, Wang ZJ, Sun DM, Wang Y, Xu P, Wu WJ, Liu XH, Zhu YZ
Oxidative medicine and cellular longevity 2017;2017:7150376
Oxidative medicine and cellular longevity 2017;2017:7150376
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Yang S, Mei S, Jin H, Zhu B, Tian Y, Huo J, Cui X, Guo A, Zhao Z
PloS one 2017;12(10):e0187017
PloS one 2017;12(10):e0187017
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Zhang X, Zhou H, Cai L, Fan C, Liu Y, Wang L, Li Q, Miao Y
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Metformin treatment after the hypoxia-ischemia attenuates brain injury in newborn rats.
Fang M, Jiang H, Ye L, Cai C, Hu Y, Pan S, Li P, Xiao J, Lin Z
Oncotarget 2017 Sep 26;8(43):75308-75325
Oncotarget 2017 Sep 26;8(43):75308-75325
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
Zhang X, Liu Y, Fan C, Wang L, Li A, Zhou H, Cai L, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Sep 26;8(43):75102-75113
Oncotarget 2017 Sep 26;8(43):75102-75113
Pro-apoptotic effect of Δ2-TGZ in "claudin-1-low" triple-negative breast cancer cells: involvement of claudin-1.
Geoffroy M, Kleinclauss A, Grandemange S, Hupont S, Boisbrun M, Flament S, Grillier-Vuissoz I, Kuntz S
Breast cancer research and treatment 2017 Oct;165(3):517-527
Breast cancer research and treatment 2017 Oct;165(3):517-527
Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion.
Wang J, Fu X, Zhang D, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Wang M, Liu X, Chen X, Zang W, Yang Q, Wang J
Neuroscience 2017 Nov 19;364:202-211
Neuroscience 2017 Nov 19;364:202-211
Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells.
Li CH, Liu CW, Tsai CH, Peng YJ, Yang YH, Liao PL, Lee CC, Cheng YW, Kang JJ
Archives of toxicology 2017 May;91(5):2165-2178
Archives of toxicology 2017 May;91(5):2165-2178
6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling.
Li Y, Xu B, Xu M, Chen D, Xiong Y, Lian M, Sun Y, Tang Z, Wang L, Jiang C, Lin Y
Pharmacological research 2017 May;119:137-148
Pharmacological research 2017 May;119:137-148
Melatonin protects against blood-brain barrier damage by inhibiting the TLR4/ NF-κB signaling pathway after LPS treatment in neonatal rats.
Hu Y, Wang Z, Pan S, Zhang H, Fang M, Jiang H, Zhang H, Gao Z, Xu K, Li Z, Xiao J, Lin Z
Oncotarget 2017 May 9;8(19):31638-31654
Oncotarget 2017 May 9;8(19):31638-31654
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
Han J, Li JH, Bai G, Shen GS, Chen J, Liu JN, Wang S, Liu XJ
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
Oral administration of propionic acid during lactation enhances the colonic barrier function.
Xia Z, Han Y, Wang K, Guo S, Wu D, Huang X, Li Z, Zhu L
Lipids in health and disease 2017 Mar 23;16(1):62
Lipids in health and disease 2017 Mar 23;16(1):62
Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood-Brain Barrier after Cerebral Ischemia Reperfusion Injury.
He F, Duan X, Dai R, Li Y, Lin Q
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Jun;26(6):1258-1265
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Jun;26(6):1258-1265
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Zhang X, Zhou H, Zhang Y, Cai L, Jiang G, Li A, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Jun 13;8(24):38863-38875
Oncotarget 2017 Jun 13;8(24):38863-38875
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Wang Y, DiSalvo M, Gunasekara DB, Dutton J, Proctor A, Lebhar MS, Williamson IA, Speer J, Howard RL, Smiddy NM, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Du J, Zhang X, Zhou H, Miao Y, Han Y, Han Q, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J
Diabetes research and clinical practice 2017 Feb;124:30-40
Diabetes research and clinical practice 2017 Feb;124:30-40
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Zhang X, Jiang G, Sun M, Zhou H, Miao Y, Liang M, Wang E, Zhang Y
Oncotarget 2017 Feb 21;8(8):13357-13366
Oncotarget 2017 Feb 21;8(8):13357-13366
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
Zhang X, Cai L, Zhou H, Liu Y, Fan C, Wang L, Li A, Miao Y, Li Q, Qiu X, Wang E
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
RCCD1 depletion attenuates TGF-β-induced EMT and cell migration by stabilizing cytoskeletal microtubules in NSCLC cells.
Wu J, He Z, Yang XM, Li KL, Wang DL, Sun FL
Cancer letters 2017 Aug 1;400:18-29
Cancer letters 2017 Aug 1;400:18-29
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Yang R, Liu W, Miao L, Yang X, Fu J, Dou B, Cai A, Zong X, Tan C, Chen H, Wang X
Oncotarget 2016 Sep 27;7(39):63839-63855
Oncotarget 2016 Sep 27;7(39):63839-63855
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Yang Z, Wang X, Chi X, Zhao F, Guo J, Ma P, Zhong J, Niu J, Pan X, Long G
Journal of virology 2016 Nov 1;90(21):9632-9643
Journal of virology 2016 Nov 1;90(21):9632-9643
Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus.
Yamamoto S, Fukuhara T, Ono C, Uemura K, Kawachi Y, Shiokawa M, Mori H, Wada M, Shima R, Okamoto T, Hiraga N, Suzuki R, Chayama K, Wakita T, Matsuura Y
PLoS pathogens 2016 May;12(5):e1005610
PLoS pathogens 2016 May;12(5):e1005610
Effect of Polysaccharides from Acanthopanax senticosus on Intestinal Mucosal Barrier of Escherichia coli Lipopolysaccharide Challenged Mice.
Han J, Xu Y, Yang D, Yu N, Bai Z, Bian L
Asian-Australasian journal of animal sciences 2016 Jan;29(1):134-41
Asian-Australasian journal of animal sciences 2016 Jan;29(1):134-41
Effects of Bacillus subtilis on Epithelial Tight Junctions of Mice with Inflammatory Bowel Disease.
Gong Y, Li H, Li Y
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 Feb;36(2):75-85
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016 Feb;36(2):75-85
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Wang ZG, Cheng Y, Yu XC, Ye LB, Xia QH, Johnson NR, Wei X, Chen DQ, Cao G, Fu XB, Li XK, Zhang HY, Xiao J
Molecular neurobiology 2016 Dec;53(10):7298-7311
Molecular neurobiology 2016 Dec;53(10):7298-7311
Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.
Lin CW, Wang LK, Wang SP, Chang YL, Wu YY, Chen HY, Hsiao TH, Lai WY, Lu HH, Chang YH, Yang SC, Lin MW, Chen CY, Hong TM, Yang PC
Nature communications 2016 Dec 22;7:13867
Nature communications 2016 Dec 22;7:13867
Sodium fluoride and sulfur dioxide affected male reproduction by disturbing blood-testis barrier in mice.
Zhang J, Li Z, Qie M, Zheng R, Shetty J, Wang J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2016 Aug;94:103-11
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2016 Aug;94:103-11
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Han J, Liu L, Yu N, Chen J, Liu B, Yang D, Shen G
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Activation of G protein-coupled estrogen receptor 1 (GPER-1) ameliorates blood-brain barrier permeability after global cerebral ischemia in ovariectomized rats.
Lu D, Qu Y, Shi F, Feng D, Tao K, Gao G, He S, Zhao T
Biochemical and biophysical research communications 2016 Aug 19;477(2):209-14
Biochemical and biophysical research communications 2016 Aug 19;477(2):209-14
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Yu X, Zhang X, Zhang Y, Jiang G, Mao X, Jin F
Oncotarget 2015 Sep 22;6(28):25034-45
Oncotarget 2015 Sep 22;6(28):25034-45
Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.
Ridder DA, Wenzel J, Müller K, Töllner K, Tong XK, Assmann JC, Stroobants S, Weber T, Niturad C, Fischer L, Lembrich B, Wolburg H, Grand'Maison M, Papadopoulos P, Korpos E, Truchetet F, Rades D, Sorokin LM, Schmidt-Supprian M, Bedell BJ, Pasparakis M, Balschun D, D'Hooge R, Löscher W, Hamel E, Schwaninger M
The Journal of experimental medicine 2015 Sep 21;212(10):1529-49
The Journal of experimental medicine 2015 Sep 21;212(10):1529-49
Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice.
Li CH, Shyu MK, Jhan C, Cheng YW, Tsai CH, Liu CW, Lee CC, Chen RM, Kang JJ
Toxicological sciences : an official journal of the Society of Toxicology 2015 Nov;148(1):192-203
Toxicological sciences : an official journal of the Society of Toxicology 2015 Nov;148(1):192-203
Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role.
Zhang X, Zhao X, Shao S, Zuo X, Ning Q, Luo M, Gu S, Zhao X
International journal of oncology 2015 Mar;46(3):1141-8
International journal of oncology 2015 Mar;46(3):1141-8
Notch1 signaling regulates the epithelial-mesenchymal transition and invasion of breast cancer in a Slug-dependent manner.
Shao S, Zhao X, Zhang X, Luo M, Zuo X, Huang S, Wang Y, Gu S, Zhao X
Molecular cancer 2015 Feb 3;14(1):28
Molecular cancer 2015 Feb 3;14(1):28
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
Zhang X, Miao Y, Yu X, Zhang Y, Jiang G, Liu Y, Yu J, Han Q, Zhao H, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Ning Q, Liu C, Hou L, Meng M, Zhang X, Luo M, Shao S, Zuo X, Zhao X
PloS one 2013;8(6):e65217
PloS one 2013;8(6):e65217
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The Occludin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Occludin. This antibody recognizes human,mouse,rat antigen. The Occludin antibody has been validated for the following applications: ELISA, WB analysis.
