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- Antibody Data
- Antigen structure
- References [2152]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 21773-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21773-1-AP, RRID:AB_10733242
- Product name
- ZO-1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ZO-1 antibody (Cat. #21773-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, Canine, mouse, rat, hamster and has been validated for the following applications: FC, IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Canine, Hamster
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Human bone marrow-mesenchymal stem cells differentiation into brain-like endothelial cells.
Targeting Myeloid FoxO1 Ameliorates Sepsis-induced Intestinal Injury by Modulating Tim4(+) Macrophage Glycolysis.
Ulinastatin attenuates capillary leakage and suppresses FoxO1-dependent angiopoietin-2 in sepsis-associated acute lung injury via PI3K pathway.
Cordycepin Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Inhibiting IL-6/IL-6R-Mediated p38 MAPK and NF-κB Activation Through Adenosine A(2A) Receptor Stimulation.
Platelet-Rich Plasma Attenuates Knee Osteoarthritis in Rats via Modulation of Gut Microbiota.
Enterotoxigenic Escherichia coli-induced intestinal epithelial necroptosis drives lamina propria immune cell pyroptosis and mucosal injury in piglets.
Modified Jiaoqi powder ameliorates ulcerative colitis through gut microbiota-tryptophan metabolism-AhR signaling modulating-ILC2/ILC3 balance.
Integrating bioinformatic prediction and the "gut microbiota-inflammation-skin axis" to decipher the mechanisms of quercetin (from Evodia rutaecarpa) in diabetic wound healing.
Akkermansia muciniphila alleviates antibiotic- and LPS-induced oxidative stress via the p38α MAPK-Nrf2 signaling axis.
2',4'-dihydroxychalcone alleviates inflammatory bowel disease by inhibiting NLRP3 inflammasome and modulating gut microbiota.
Prim-O-glucosylcimifugin ameliorates DSS-induced ulcerative colitis via suppressing NLRP3 inflammasome activation.
Lactobacillus rhamnosus confers protection against enteropathogenic bacteria by enhancing mucosal immunity and epithelial barrier function.
Rosuvastatin attenuates blood-brain barrier dysfunction after ICH through modulation of CXCL12-associated VEGFR2/p38 MAPK signaling.
Gut microbiota mediates the antidepressant-like effects of xiaochaihutang: mechanisms involving inhibition of inflammation and enhancement of barrier function.
Puerarin Improves Glucose and Lipid Metabolism in Type 2 Diabetes by Regulating Gut Microbiota Homeostasis and Promoting Adipose Tissue Thermogenesis.
Yeast β-glucan alleviates alcohol-related brain injury by restoring gut-brain axis homeostasis.
RIPK1-driven calcium overload and lysosomal-mitochondrial dysfunction induce testicular necroptosis following DEHP exposure.
Mucin alleviates HFD-induced obesity and MASLD via an Akkermansia muciniphila-associated mucin-Neu5Ac-PPARα signaling axis.
Bufei Jianspi formula alleviates intestinal epithelial barrier injury by inhibition of calpain 2 in COPD rat.
Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol-Induced Intestinal Injury via Microbiota-Dependent and -Independent AHR Activation.
Effect of Dietary Electrolyte Balance in Low-Protein Diet on Intestinal Barrier, Mitochondrial Function and Carcass Quality of Growing Pigs.
Multi-omics dissection of lignan diversity and therapeutic potential in Ocimum: Identification of diphyllin as an anti-inflammatory agent targeting TNF-α signaling.
Gynostemma pentaphyllum polysaccharides alleviate ulcerative colitis in mice via the Nrf2/ROS/NLRP3 axis and modulation of the gut microbiota.
Dietary N-acetylneuraminic acid maintains intestinal homeostasis and protects against aging- and inflammation-associated colonic dysfunction.
Naringin alleviates autoimmune hepatitis in mice via the gut-liver Axis through modulation of microbiota, metabolites, and immune responses.
Inflammation-responsive framework nucleic acids for ulcerative colitis therapy.
Dual-action nasal spray with mussel protein and xylitol restores epithelial barrier and attenuates type 2 inflammation in allergic rhinitis.
Therapeutic potential of Isatidis Radix alkaloids in RSV pneumonia: A focus on AhR-mediated pulmonary barrier repair.
Fermented grape pomace alleviates Salmonella typhimurium-induced Hepatointestinal inflammation: FXR mediates protection by orchestrating bile acid homeostasis and suppressing the colonic NLRP3 Inflammasome.
Small extracellular vesicles derived from hair follicle neural crest stem cells enhance perineurial cell proliferation and migration via the TGF-β/SMAD/HAS2 pathway.
Deficiency of exocyst complex component Exoc5 exacerbates the progression of kidney fibrosis.
c-MAF Transcriptionally Activates Slc40a1 to Repress Ferroptosis in Sepsis-Associated Encephalopathy.
LC3-positive extracellular vesicles released from tumor cells promote lung metastasis of breast cancer by inducing vascular permeability.
Scutellaria baicalensis extract prevents metabolic dysfunction-associated steatotic liver disease by modulating the gut-liver axis in high-fat diet mice.
Engineered Bacillus subtilis WB600/ZD reduces post-weaning diarrhea in piglets by modulating gut microbiota and aryl hydrocarbon receptor (AHR) signaling.
Protective impacts of berberine in weaned piglets fed without zinc oxide: Insight of jejunal barrier function, water absorption, and gut microbiota and metabolism.
Reversibly unlocking the blood-brain barrier: A study on microtubule dynamics modulation using gold nanoparticle-modified reduced graphene oxide.
A mitochondrial-derived peptide MOTS-c contributes to the protective effect against brain injury associated with LPS-induced sepsis by strengthening the blood-brain barrier's ultrastructure.
Western Diet Inhibits FUT7-Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease.
TRIM27-controlled endothelium-derived exosomes play a central role in podocyte injury in diabetic kidney disease.
RAB3B regulates vesicle uptake and tight junction integrity in amniotic epithelial cells and is downregulated in premature rupture of membranes.
Nitric Oxide Donor Alleviates Cardiac Arrest Induced Blood Brain Barrier Injury by Inhibiting HMGB1-ATG5 Mediated Endothelial Autophagy.
Lactobacillus reuteri SKLAN202402ZF inhibited by early-life lincomycin exposure alleviate intestinal damage and inflammation sensitivity.
Complement protein C1q induces endothelial apoptosis through C1qBP regulation of mitochondrial function in lung endothelial cells in systemic sclerosis.
Daidzein Confers Prophylactic Protection against Food Allergy by Restoring Immune Regulation, Intestinal Barrier Integrity, and Microbiota-Metabolite Homeostasis.
Odevixibat ameliorates high-fat diet-induced MASLD in mice by targeting the gut microbiota-metabolite axis and enhancing gut-liver crosstalk.
Lactiplantibacillus pentosus JWN01 and Lactiplantibacillus plantarum JWN02 attenuate renal fibrosis and pathological autophagy in hyperuricemic nephropathy via gut-kidney axis.
ALKBH5 facilitates Srgn stability via m6A demethylation to disrupt blood-testis barrier integrity in the high-fat diet mice.
Ketogenic diet alleviates septic lung injury via microbial gut-lung axis.
Gut microbiota and metabolomic alterations underlying the therapeutic effects of SQJZ capsules in a rat model of chronic renal failure.
Chronic Excessive Exposure to Fluoride Impairs the Intestinal Mucosal Barrier to Cause Inflammatory Response and Microbiome Dysbiosis in Rats.
Spiky Nanoparticle-Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder.
Protective Effect of Bifidobacterium longum subsp. infantis E4 Exopolysaccharide on Intestinal Barrier, Regulation of Gut Microbiota and Metabolite In Vitro, and Immunosuppressed Mice.
β1,4-galactosyltransferase III drives retinoblastoma invasion via activation of integrin-FAK axis.
MyD88 inhibitory Peptide-2 (MIP2) improves neurological outcomes and reduces neuroinflammation after intracerebral Hemorrhage-mediated secondary brain injury.
Curculigoside attenuates influenza virus-induced acute lung injury by modulating the Keap1/Nrf2 signaling pathway.
Exploring the mechanism of Qinlian Yuyang Decoction in the treatment of ulcerative colitis based on multi-omics technology.
SGK1 Is Upregulated in Retained Placenta and Mediates Estradiol Effects in Bovine Endometrial Cells.
Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy.
Quercetin Ameliorates Comorbid Insomnia in Diarrhea-Predominant Irritable Bowel Syndrome via the PI3K/AKT/NF-κB Signaling Pathway.
Transcriptomics and metabolomics reveal functional nanoplastics-induced male reproductive damage and resveratrol antagonistic effects.
tLyP-1 peptide-modified MnO₂ co-delivering si-SLC16A1 and temozolomide synergistically suppresses glioblastoma via hypoxia modulation and metabolic stress.
Glycine alleviates the intestinal epithelial barrier damage induced by imidacloprid via promoting metabolic detoxification.
Renal Tubule-Specific Deletion of Nephrocystin 3 (Nphp3) Causes Infantile Nephronophthisis-like Phenotypes in Mice.
A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation-Dependent Cell Adhesion.
Synergistic disruption of the blood-brain barrier in tree shrews by Methamphetamine and HIV-1 Tat via TRPM2-Mediated astrocyte inflammation.
Identification of Ellagic Acid as a Natural GPR35 Agonist for Ulcerative Colitis Therapy.
Glibenclamide Attenuates Brain Edema After Intracerebral Hemorrhage Through Preservation of Blood-Brain Barrier Integrity and Glymphatic Function.
Dietary semen cuscuta improves laying performance by stabilizing mitochondria-associated membranes (MAMs) and inhibiting granulosa cell apoptosis in laying hens.
Shenqi funeng xingnao prescription regulated the TNF/NOD‒like receptor signaling pathway and brain-gut axis dysfunction caused by exercise-induced fatigue.
High fluoride exposure disrupts gut microbiota and induces intestinal barrier damage via RhoA/ROCK-mediated cytoskeletal remodeling.
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
Berberine alleviates soybean meal-induced enteritis in hybrid yellow catfish (Pelteobagrus fulvidraco ♀ × Pelteobagrus vachelli ♂) by regulating intestinal microbiota and tryptophan metabolism.
Limbal organoids and bioengineering sheets based on niche microphysiological systems and bioprinting for corneal injury repair in rabbits.
The Scutellaria baicalensis-Coptis chinensis herb pair ameliorates ulcerative colitis via integrated modulation of the aryl hydrocarbon receptor/NLRP3 inflammasome axis with tryptophan metabolites.
Senkyunolide I attenuates radiation-induced cognitive dysfunction by restoring PINK1-Parkin-mediated mitophagy and redox homeostasis.
Rhubarb ameliorates ischemic stroke-induced tryptophan-kynurenine metabolic reprogramming and neuroinflammation via modulation of the IDO-1/TREM-1 pathway.
Modified Ganlu Xiaodu decoction attenuates airway barrier injury in Mycoplasma pneumoniae pneumonia by inhibiting ZBP1-mediated PANoptosis.
Huanglian muxiang decoction alleviates FTH-mediated ferroptosis in colitis by inhibiting the PI3K-AKT pathway.
Dehydroandrographolide succinate alleviates ulcerative colitis via regulating RAB9A/NF-κB axis-mediated macrophage polarization and remodeling the gut microbiota.
Synergistic tissue destruction by Staphylococcus aureus and Staphylococcus epidermidis in a 3D human skin biofilm equivalent.
EDIL3 regulates caveolin-1-dependent endothelial permeability in subchondral bone during osteoarthritis.
Swertia chirayita ameliorates MAFLD by improving intestinal microenvironment and hepatic lipogenesis.
Immune-epithelial dual-targeting bilirubin nanoparticles for acute lung injury.
Beneficial effects of electro-acupuncture treatment in photothrombotic ischemia model rats by remodeling neurovascular unit.
Zanthoxylum bungeanum essential oil alleviates DSS-induced ulcerative colitis in mice by modulating gut microbiota-dependent AhR/Nrf2 signaling.
The immunomodulatory metabolite butyrate ameliorates renal fibrosis by restoring gut barrier integrity and suppressing the TGF-β1/Smad3 pathway.
Spatiotemporally engineered microneedle for microenvironment remodeling propels mucosal regeneration after tracheal mucosal injury.
Inhibition of endothelial ALOX12 mitigates cerebral ischemia-reperfusion injury by suppressing 12-HETE.
Shaoyao Gancao Decoction alleviates ulcerative colitis-associated secondary liver injury by inhibiting the phosphorylation of pyruvate dehydrogenase in macrophages.
Dual benefits of Xiao Chai Hu Tang and its active compounds in CPT-11 therapy: intestinal protection via barrier restoration and anti-inflammation combined with enhanced tumor apoptosis.
Methyl 3-chloroasterric acid exerted anti-neuroinflammatory and antidepressant effects through the downregulation of P2Y1R.
COXFA4L3 enhances mitochondrial complex IV function to boost ATP synthesis and drive sperm motility.
Metformin attenuates colitis via blocking STAT3 acetylation by reducing acetyl-CoA production.
Targeting PTPN13 with 11-amino-acid peptides of C-terminal APC prevents immune evasion of colorectal cancer.
Bacterial cellulose repairs asthmatic epithelial injury by reprogramming CDS1-mediated phosphatidylinositol metabolism to inhibit PI3K/AKT signaling.
Selective peptide-guided transcytosis enhances extracellular vesicle-mediated siRNA delivery across the blood-brain barrier.
PFOS-induced black liver and hepatic aging in mice: A new paradigm in environmental hepatotoxicology.
Increased glucose transporter 1 contributes to epithelial barrier dysfunction in allergic rhinitis.
Unraveling the active ingredients and molecular mechanisms of Qinghua Changyan granule against irritable bowel syndrome with diarrhea: Effects on gut microbiota and glutamine transport via an integrative approach combining UHPLC-MS/MS and experimental verification.
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
Targeted demethylation of the BRD7 promoter based on CRISPR/dCas9 system inhibits the malignant progression of nasopharyngeal carcinoma.
FABP4-mediated lipid droplet accumulation drives epithelial-mesenchymal transition and aggravates alveolar epithelial barrier disruption.
Inhalable songorine-integrated lipid nanomedicine for targeted ARDS therapy via repairing endothelial barrier and inactivating NLRP3 inflammasome.
Elucidating the mechanism of traditional Chinese medicine formula (Yifei-sanjie Pill) in alleviating the chemobrain based on network pharmacology and experimental verification.
Nutritional Modulation of Melatonin-SIRT1 Signaling by Octanoic Acid-Rich Enteral Nutrition Protects Against Radiation-Induced Intestinal Injury.
Lactobacillus Salivarius-Derived Indole-3-Acetic Acid Promotes AHR-PARP1 Axis-Mediated DNA Repair to Mitigate Intestinal Aging.
Inhibiting Liver-Derived C3 Protein Rescues Anesthesia/Surgery-Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis.
Scutellarein from Erigeron breviscapus Inhibits Apoptosis-Mediated Epithelial Barrier Disruption and Alleviates Cigarette Smoke-Induced Lung Injury.
Ptbp2 Alleviates Neuroinflammation and Blood-brain Barrier Disruption via Modulating Microglial Polarization in Ischemic Stroke.
Chaihu Longgu Muli Decoction attenuates chronic stress-induced endothelial dysfunction and potentiates chemotherapy in breast cancer by inhibiting cAMP/PKA/CREB1 mediated glycolysis.
Comparative studies on the components and anti-ulcerative colitis effects of raw and carbonized Linderae Radix.
Chrysophanein of Rhubarb rescues ILC3-Derived IL-22 by blocking CCDC25/ILK/HIF-1α for mucosal healing in ulcerative colitis mice.
A Feline Milk-Drived Pediococcus acidilactici M22 Alleviates Escherichia coli O157:H7 Infection Through Anti-Adhesion, Anti-Inflammation, and Microbiota Modulation.
A 3D-Printed Pump-Free Multi-Organ-on-a-Chip Platform for Modeling the Intestine-Liver-Muscle Axis.
Gut metabolite indole-3-acetic acid aggravates neuropsychiatric lupus via the AHR/STAT3 pathway in microglia.
Danthron Attenuates Intestinal Inflammation by Modulating Oxidative Stress via the EGFR-PI3K-AKT and Nrf2-HO-1 Pathways.
Brain capillary endothelial-like cells show altered barrier functionality and reduced transport of amyloid β in late-onset Alzheimer disease.
Strategically isolated bacteriophages targeting ETEC K88 (F4) alleviate post-weaning diarrhea in piglets via modulation of gut microbiota and inflammatory responses.
Calcium carbonate supplementation exacerbated gut microenvironment disruption in senile osteoporosis mice.
Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers.
Luteolin Enhances Endothelial Barrier Function and Attenuates Myocardial Ischemia-Reperfusion Injury via FOXP1-NLRP3 Pathway.
Natural Dietary Flavonoid Apigenin Mitigates Ulcerative Colitis via Modulating the AMPK/NF-κB/NLRP3 Signaling Axis.
Fecal microbiota transplantation from healthy piglets ameliorates intestinal inflammation in mice by modulating recipient metabolism.
Clostridium perfringens Type A Isolated from Intestinal Contents of Alpaca.
Flash nano-encapsulation of probiotics: Bolstering environmental resistance and intestinal colonization to prevent necrotizing enterocolitis.
Effects of Modified Xuanbai Chengqi Decoction against secondary Streptococcus pneumoniae infection following influenza virus infection: A multi-omics analysis.
Investigating the Protective Mechanisms of Ginseng-Natto Composite Fermentation Products in Alzheimer's Disease: A Gut Microbiota and Metabolomic Approach.
Activation of Intestinal Mast Cells Contributes to Gut Damage After Cardiac Arrest in Mice.
Inulin with different degrees of polymerization adopts different strategies to mitigate radiation-induced intestinal injury: focus on intestinal epithelial or T cell homeostasis.
Chitosan alleviates symptoms of Parkinson's disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood-brain barrier.
HPGDS promotes tubular injury and interstitial inflammation in diabetic nephropathy by activating canonical pyroptosis pathway.
Obacunone inhibits RIPK1/RIPK3/MLKL-mediated necroptosis by suppressing mitochondrial ROS and MIF signaling in intestinal ischemia-reperfusion injury.
Combined metabolomics and gut microbiota analysis reveals the protective effects of α-monoglucosyl rutin against cyclophosphamide-induced intestinal injury.
Ganoderic Acids Alleviate Neuroinflammation by Targeting Myeloid Differentiation Factor 2 for Ischemic Stroke Therapy.
AURKA modulates tight junction functionality to influence the proliferation and metastasis of lung adenocarcinoma.
Improving glucose tolerance in obese rats: the role of Jinlida granules ( ) in gut microbiota modulation.
Repairing effect of total glucosides of Paeonia on deoxynivalenol-induced enterohepatic axis damage in weaned piglets.
Bacteroides acidifaciens alleviates high-fat diet-induced obesity-related osteoporosis by regulating gut microbiota and bile acid metabolism via the gut-bone axis.
Meningitic Escherichia coli disrupts the blood-brain barrier through pyroptosis and tight junction degradation and NLRP6 deficiency aggravates infection outcomes.
Resveratrol Inhibits Pancreatic Cancer Progression by Regulating CDC42 Succinylation and Disrupting the Extracellular Matrix.
Dynamin-Related Protein 1-Dependent Disruption of Mitochondrial Homeostasis Drives Blue Light-Induced Epithelial-Mesenchymal Transition in Retinal Aging.
Engineered probiotics for the in vivo mitigation of waterborne uranium toxicity and bioaccumulation.
Oral colon-targeted paeonol emulsion for ameliorating ulcerative colitis based on charge adsorption.
MiR-21 modulates P.g-LPS induced apoptosis and inflammatory response in HUVECs via NF-κB/iNOS/NO pathway by targeting PDCD4.
Acute sleep deprivation reduces thermotolerance and exacerbates heat stroke via disruption of intestinal barrier integrity in rats.
Brd4 BD1 Domain Antagonism of MS436 Preserves Blood-Brain Barrier Integrity via Rnf43/β-Catenin Signaling Pathway.
Mettl3-Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS.
Uropathogenic Escherichia coli invade luminal prostate cells via FimH-PPAP receptor binding.
Sulfated Pelvetia siliquosa Polysaccharides Attenuate Pyroptosis via NF-κB Pathway Inhibition Against Calcium Oxalate Stone Formation.
DMBX1 expression in colon cancer and its impact on prognosis and the tumor microenvironment.
Inhibition of macrophage pyroptosis protects against sepsis-induced injury to the alveolar epithelial barrier.
Bacteroides coprocola protects dopaminergic neurons in rotenone-induced Parkinson's disease mouse model by modulating gut microbiota dysbiosis and inhibiting the NLRP3 signaling pathway.
The Protective Effects and Underlying Mechanisms of Taraxacum kok-saghyz Polysaccharides Against Intestinal Dysbiosis-Induced Mastitis Were Elucidated Using a Murine Model of the "Gut-Mammary" Axis.
Self-Assembled Rg3/Naringenin Nanoparticles for Targeted Brain Delivery: A Promising Therapeutic Approach for Early Alzheimer's Disease.
Cobalt Metal-organic Framework Alleviates DSS-Induced Ulcerative Colitis Via Barrier-protective and Immunomodulatory Effects.
Gut microbiota-derived trimethylamine N-oxide contributes to cardiomyocyte pyroptosis and cardiac injury via the tRF-Glu-ANT1-GSDMD axis.
TAS2R46 activation protects intestinal barrier from chronic high glucose.
Gut microbiota dysbiosis contributes to diabetic nephropathy via affecting renal lipid deposition and inflammatory responses.
Construction of an In Vitro Blood-Brain Barrier Micro-Organoid Model Using Decellularized Squid Mantle Scaffold Film.
Gut Lachnospiraceae improves white matter injury-related cognitive decline by increasing L-arginine.
Butyrate ameliorates doxorubicin-induced heart failure by inhibiting cardiomyocyte ferroptosis through the gut-heart axis.
Adenosine from high-fat-diet-tolerant monkey-derived Limsolactobacillus reuteri MacFasB02 modulates cholesterol metabolism to alleviate hyperlipidemia and inflammation.
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
Metagenomics and Machine Learning Identify TMA-Producing Serratia Induced by High-Fat/Choline Diet: A Novel Obesity Target for TMA.
Development and characterization of immortalized mouse intestinal epithelial cell lines.
Lactiplantibacillus plantarum GUANKE ameliorates influenza a virus-induced inflammation and lung barrier dysfunction through enhancing mitophagy and improving oxidative phosphorylation.
Integrating serum pharmacochemistry, network pharmacology, gut microbiota and transcriptomic strategies to reveal the active ingredients and mechanism of Changma Xifeng tablet in the treatment of tourette syndrome.
Glimepiride alleviates blood-brain barrier disruption and neuroinflammation in mice with intracerebral haemorrhage.
Gut-confined fullerene reprograms lactate metabolism to Rescue hypoxia-induced exercise intolerance.
Caspase-4/11-mediated non-canonical pyroptosis disrupts blood-brain barrier integrity via VEGFA/VEGFR2 signaling in Escherichia coli meningitis.
Atractylenolide III Alleviates the Lipid Metabolic Disorders in Ovariectomy-Induced Estrogen-Deficient Mice Through Repairing Intestinal Inflammation and Microenvironment.
Qiming Granules Ameliorate Diabetic Retinopathy by Regulating the PI3K/Akt Signaling Pathway.
Carrier-free supramolecular architectonics of quercetin-berberine for safety-redefined therapy of ulcerative colitis.
Intestinal epithelial protection and gut microbiota modulation by Ganoderma lucidum proteoglycan are associated with its hypoglycemic potential in type 2 diabetes.
HSP70 preserves brain microvascular endothelial integrity under heat stress associated with suppressed JNK-mediated apoptosis and mitophagy.
Panax notoginseng saponins protect the blood-brain barrier against oxidative stress by activating the Akap12-PI3K/AKT-AQP1 signaling axis.
Inhibition of Transglutaminase 2 Preserves Blood-Brain Barrier Integrity and Improves Neurological Outcomes After Experimental Traumatic Brain Injury in Mice.
Remimazolam alleviates blood-brain barrier damage by regulating the PI3K/AKT signaling pathway in sepsis-associated encephalopathy mice.
Protective Effects of Bifidobacterium bifidum Strains with IgA-Potentiating Activity Against ETEC Infection in Weanling Mice.
Integrated network pharmacology, transcriptomics and experimental validation to explore mechanisms of Wenyang Jiedu Granule on IAV-induced pneumonia.
Polystyrene microplastics exposure increases the disruption of intestinal barrier integrity and gut microbiota homeostasis during obesity and aging.
Mechanism of Gzma-mediated GEF-H1 activation in intestinal epithelial cells leading to intestinal barrier dysfunction in sepsis.
The ovarian tumor domain-containing protein 4 (OTUD4)-targeted ferroptosis inhibitor Maclekarpine E attenuates ulcerative colitis.
Brucea javanica oil emulsion ameliorates ulcerative colitis by upregulating Deoxyribonuclease 2 to suppress cytosolic DNA-sensing signaling.
Xanthoxylin alleviates dextran sulfate sodium (DSS)-induced colitis by targeting macrophage infiltration via the tumor necrosis factor (TNF) /nuclear factor-kappa B (NF-κB) signaling pathway.
Homoplantaginin alleviates high glucose-induced vascular endothelial barrier dysfunction by regulating Yes-associated protein 1.
Jiawei Danxuan Koukang and Its Component Kaempferol Alleviate Oral Submucous Fibrosis by Restoring Epithelial-Fibroblast Homeostasis and Suppressing Neutrophil Recruitment via the ANXA1/FPR2 Axis.
ADAMTS2 Modulates Inflammation, Autophagy, and Barrier Integrity Through PI3K/AKT/mTOR Signaling in LPS-Induced Acute Respiratory Distress Syndrome.
Polydopamine-Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus.
Diabetes Mellitus Facilitates Gallstone Formation Through CXCR2-NETs-Mediated Liver-Bile Barrier Damage.
Neuroprotective Effects of Time-Restricted Feeding Combined With Different Protein Sources in MPTP-Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism.
Advanced glycation end products promote Porphyromonas gingivalis dissemination via an ROS-dependent, inflammation-independent mechanism.
RhoB supports rubella infection and impairs endothelial barrier integrity through downstream ROCK signaling.
Head-down position after reperfusion improves cerebral ischaemic injury in rat.
Oral Exposure to Polypropylene Microplastics Exacerbates Cow's Milk Allergy in a Murine Model by Skewing the DCs/T-Cell Response toward Th2 Polarization.
Ophiopogon japonicus Polysaccharides Promote Microbial Production Of Chenodeoxycholic Acid To Alleviate Ulcerative Colitis in Mice by Inhibiting the STING1-Related NF-κB Pathway.
Vitamin D(3) Metabolite-Enhanced Hepatic VDR-FXR Binding Attenuates Bile Acid Dysregulation-Induced Diarrhea in Weaned Piglets.
Biomimetic mitochondria-targeted drug delivery system for the treatment of inflammatory bowel disease.
Gut microbiota: A critical regulator of oxaliplatin-induced peripheral neurotoxicity development.
Macrophages with ITIH4 overexpression attenuate inflammatory responses and regulate intestinal epithelial cells.
Atmospheric particulate matter impairs pulmonary barriers by triggering FTH1-mediated ferroptosis.
Metabolic Engineering of Commensal Bacteria for Producing 5-Hydroxyindoleacetic Acid as a Therapeutic Strategy for Colitis.
Intermittent fasting protects MPTP-induced Parkinson's disease mouse model through regulating gut microbiota dysbiosis.
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
Phenethyl Isothiocyanate Suppresses Hepatocellular Carcinoma Progression and Immune Evasion via ZNF652 Regulation of PD-L1.
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus.
Hexavalent chromium exposure disrupts gut microbial structure and metabolic function in broiler chickens.
Abnormal glycosylation of MUC20 mediates TAM polarization and promotes immune escape in colorectal cancer.
Puerarin Alleviates Depression via Integrated Regulation of TLR4/MyD88/NF-κB Signaling and Gut Microbiota-Metabolic Axis.
Integrated transcriptomic and metabolomic analyses reveal distinct energy metabolic signatures and functional properties of RPE cells under two culture conditions.
LncRNA RP11-510J16.3 exacerbates sepsis-associated encephalopathy by facilitating NLRP3-dependent pyroptosis through miR-1290 sequestering.
PCYT1A Hypophosphorylation Underlies Retinal Lipid Dysregulation in CERKL Retinitis Pigmentosa and Is Therapeutically Reversed by Phosphatidylcholine.
Probiotic Bifidobacterium Confers Protection Against Heat Stroke Through Enhancement of Intestinal Barrier Function in Rats.
Airborne PM(2.5) from pig houses induces piglet respiratory epithelial barrier injury by activating the NLRP3 inflammasome through Drp1-mediated mitochondrial dysfunction.
An indoloquinolinone 3a alleviates lipopolysaccharide-induced acute lung injury by modulating the NF-κB and AMPK/Nrf2 signaling pathways.
Increased PRSS56 expression is a causal factor and therapeutic target for human axial high myopia.
Predictive value of plasma zonulin for postoperative Hirschsprung-associated enterocolitis.
Canine-derived Weissella confusa ZJUIDS-D034 and Enterococcus faecalis ZJUIDS-D016 combat aging by regulating gut microbiota.
The role of the gut microbiota and the nicotinate/nicotinamide pathway in rotenone-induced neurotoxicity.
A Hepatic Oxidative Metabolite of Palmatine Ameliorates DSS-Induced Ulcerative Colitis by Regulating Macrophage Polarization Through AMPK/NF-κB Pathway.
α-hederin Targets USP5 to Inhibit Colorectal Tumorigenesis by Disrupting STAT3 Deubiquitination.
Comparisons of the Effects of Low- or High-Fat Diets Rich in Soybean Oil, Lard, and Tea Seed Oil on Markers of Blood-Brain Barrier and Neuroinflammation in Ovariectomized Mice.
Integrating network pharmacology and experimental verification to explore the protective effects of Evodia rutaecarpa in ischemic stroke.
LncRNA NEAT1 protects uremic toxin-induced intestinal epithelial barrier injury by regulating miR-122-5p/Occludin axis.
Curcumin ameliorates aging-induced blood-testis barrier disruption by regulating AMPK/mTOR mediated autophagy.
Curcumin modulated gut microbiota and alleviated renal fibrosis in 5/6 nephrectomy-induced chronic kidney disease rats.
Functional Liposomes Improve the Oral Absorption of Lurasidone Hydrochloride by Overcoming Multiple Absorption Barriers and Eliminating Food Effect.
SIGIRR Alleviates Intestinal Mucosal Damage in Severe Acute Pancreatitis via the TLR4 Signaling Pathway.
Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways.
Gegen Qinlian Decoction Ameliorated DSS-Induced Colitis by Attenuating Inflammation, Restoring Intestinal Mucosal Barrier and Modulating Gut Microbiota.
Spermidine Exerts Neuroprotective Effects Following Intracerebral Hemorrhage in Mice Through Anti-Inflammation and Blood-Brain Barrier Protection.
Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway.
Kuiyangling Enema Alleviates Ulcerative Colitis Mice by Reducing Levels of Intestinal NETs and Promoting HuR/VDR Signaling.
Tenascin-C Facilitates Microglial Polarization via TLR4/MyD88/NF-κB Pathway Following Subarachnoid Hemorrhage.
Berberine Repairs Intestinal Mucosal Barrier by Targeting HSP90AA1 and MAPK14.
Isoorientin Modulates Gut Microbes and Their Metabolites to Alleviate Caco-2 Cell Monolayer Inflammation by Reducing Intestinal Permeability via P-Gp/eCBs.
Yuyang Decoction Regulates Macrophage Polarization and Repairs the Intestinal Mucosal Barrier via the TLRs/Tollip Signaling Pathway.
Network pharmacology-guided investigation of Fuzheng Yanggan Huaxian decoction in a CCL(4)-induced hepatic fibrosis mouse model: involvement of the TLR4-MAPK/NF-κB signaling axis and intestinal barrier.
Dysregulation of the microbiota-gut-brain axis induced by chronic pancreatitis mediates anxiety- and depression-like behaviors in mice.
Deciphering immune cell interaction aberrations in necrotizing enterocolitis: the regulatory role of DHRS7.
Nrf2/HO-1-dependent inhibition of ferroptosis underlies the antioxidant effects of 5-O-methylvisammioside in colitis.
Dahuang gancao dandelion decoction regulates intestinal flora and inhibits NF-κB/ARA signaling pathway to alleviate ulcerative colitis.
Akkermansia muciniphila and its culture supernatant ameliorate colitis in interleukin-10 knockout mice via gut barrier and immune modulation.
Macrophage TRIM21 lactylation exacerbates infection-induced orchitis through enhancing STAT1-mediated CXCL9 and CXCL10 production.
Lyophyllum decastes-derived polysaccharides alleviate DSS-induced colitis in mice by suppressing inflammation, enhancing intestinal barrier integrity, and restoring gut microbiota homeostasis.
Barnesiella intestinihominis improves gut microbiota disruption and intestinal barrier integrity in mice with impaired glucose regulation.
Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin.
Schisandrin B alleviates metabolic associated fatty liver disease by regulating the PPARγ signaling pathway and gut microbiota in mice.
2-Dodecyl-6-methoxycyclohexa-2,5-dien-1,4-dione alleviates liver fibrosis and improves intestinal flora and bile acid metabolism.
Metformin improves intestinal ischemia-reperfusion injury by reducing the formation of mitochondrial associated endoplasmic reticulum membranes (MAMs) and inhibiting ferroptosis in intestinal cells.
Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice.
Roles of MASP-1 and MASP-3 in the development of retinal degeneration in a murine model of dry age-related macular degeneration.
Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia.
Umbelliferone as an effective component of Rhodiola for protecting the cerebral microvascular endothelial barrier in cSVD.
Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway.
Thlaspi arvense suppresses gut microbiota related TNF inflammatory pathway to alleviates ulcerative colitis.
Acupuncture alleviates hemorrhagic transformation after delayed rt-PA treatment for acute ischemic stroke by regulating the mitophagy-NLRP3 inflammasome pathway.
Aqueous extracts of Elsholtzia ciliata and Hovenia dulcis ameliorate loperamide-induced constipation in mice by promoting intestinal peristalsis and barrier function and the abundance of intestinal beneficial bacteria.
Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.
Traditional Mongolian Medicine Qiqirigan-8 alleviates non-alcoholic fatty liver disease via restoring gut microbiota and metabolism.
Liqi Yangyin formula ameliorates CUMS-induced depression and comorbid constipation via ACE/FFAR2 modulation of the microbiota-gut-brain axis.
Ellagic acid mitigates rotavirus-induced intestinal injury via bidirectional "immune-microbiota" regulatory effect.
Porphyromonas gingivalis-induced periodontitis promotes neuroinflammation and neuronal loss associated with dysfunction of the brain barrier.
Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity.
Chaihuang Qingyi Huoxue granule ameliorates severe acute pancreatitis by modulating gut microbiota and repairing the intestinal mucosal barrier.
Histone lactylation exacerbates acute lung injury in septic mice by promoting ferroptosis in pulmonary microvascular endothelial cells.
Fibroblast exosomes promote wound healing and improve the quality of healed skin via miR-29a-3p-mediated KEAP1/Nrf2 pathway activation.
Gasdermin E-mediated intestinal epithelial pyroptosis promotes chemically induced colitis in mice.
L-cysteine mitigates busulfan-induced testicular injury through modulation of CBS/H(2)S axis.
Preclinical evaluation of 6-Gingerol in modulating gut microbiota and SCFAs to mitigate Clostridium difficile-associated diarrhea in mice.
Multi-omics elucidation of Lactiplantibacillus plantarum NKK20 in preventing PCOS via the gut-ovary axis: SCFAs-mediated microbiota-metabolite-immune crosstalk.
The role of Sophora alopecuroides alkaloids in colon health of lambs fed high-concentrate diets for extended periods: impact on barrier function, antioxidation, and microflora.
Study on the role of the combination of quercetin and lutein in alleviating ulcerative colitis in mice.
Oral administration of curcumin and quercetin nanoparticles can improve ulcerative colitis by regulating intestinal microorganisms.
Therapeutic potential of Glycyrrhiza polysaccharides in pseudorabies virus infection: immune modulation, antioxidant activity, and gut microbiota restoration.
Vespa orientalis pupae peptide hydrolysates modulate NF-κB signaling in LTA-induced pneumonia from clinical Enterococcus faecalis isolates: implications for gut microbiota.
Luteolin attenuates LPS-induced damage in IPEC-J2 cells by enhancing mitophagy via AMPK signaling pathway activation.
Studies on the alleviating effect of Bifidobacterium lactis V9 on dextran sodium sulfate-induced colitis in mice.
Lignans-rich extract of Schisandra chinensis prevent alcohol-associated liver disease by regulating the gut microbiota and tryptophan metabolism.
Stachyose alleviates high-fat diet-induced obesity via browning of white adipose tissue and modulation of gut microbiota.
A pectic polysaccharide from Lycium ruthenicum Murray alleviates dextran sulfate sodium-induced colitis in mice.
Benzo[a]pyrene aggravated ovalbumin‑induced epithelial tight junction disruption via ROS driven‑NLRP3/Caspase‑1 signaling pathway in asthmatic mice.
Nucleotide-binding domain-like receptor protein 3 inflammasome contributes to vascular endothelial barrier dysfunction and shock after burn injury.
A novel glucomannan from Bletilla striata ameliorates colitis: Restores intestinal barrier, alleviates inflammation, and modulates the gut flora.
Ovotransferrin ameliorated intestinal barrier dysfunction in DSS-induced ulcerative colitis mice via inhibition of PI3K-Akt/MAPK signaling pathways and modulation of tissue metabolism.
Associations between the effectiveness of sleeve gastrectomy and the composition and function of gut microbiome in obese rats.
Protective effects of artesunate on the neurovascular unit by regulating PDGFRβ signaling in experimental cerebral malaria.
TBX21 knockdown attenuates neuroinflammation induced by intracerebral hemorrhage via the SIRT1-WDR5-H3K4me3 axis.
TIMP1 inhibits Rac1-mediated ROS production to ameliorate blood-spinal cord barrier disruption in amyotrophic lateral sclerosis.
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD.
Gut dysbiosis exacerbates inflammatory liver injury induced by environmentally relevant concentrations of nanoplastics via the gut-liver axis.
Wendan Decoction exerts therapeutic effects on insomnia by regulating gut microbiota and tryptophan metabolism.
Study on the effects of the atractylodes macrocephala koidz-raphanus sativus l herb pair in alleviating senile constipation via the gut microbiota-SCFAs-5-HT axis.
HDAC/NF-κB signaling pathway mediates gut microbiota dysbiosis in rheumatoid arthritis: Intervention mechanisms of Fengshining decoction.
Caffeic acid improves intestinal barrier function integrity through activation of Nrf2 signaling pathway in weaned piglets and H(2)O(2) induced IPEC-J2 cells.
Neonatal necrotizing enterocolitis attenuates adult asthma via eosinophil ferroptosis.
Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia-Reperfusion Injury.
Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT.
Microenvironment-driven transformable self-assembly nanoplatform enables spatiotemporal remodeling for rheumatoid arthritis therapy.
Role of Necroptosis and Neuroinflammation in CSVD-Associated Cognitive Decline in db/db Mice.
Microbiota-mediated metabolic alterations reveal bidirectional regulation of the gut-nose axis in mice with allergic rhinitis.
Salecan Suppresses Pancreatic Cancer Progression by Promoting Necroptosis via the RIPK1/MLKL Pathway.
Protective effects of Dachengqi Decoction in sepsis-associated liver injury based on network pharmacology analysis and experimental validation.
Zhutong Decoction relieves constipation by enhancing intestinal peristalsis through modulation of C-KIT/ANO1 and PDGFRα/SK3 in the SIP syncytium.
Shenling Baizhu Powder and Betulin attenuate sepsis-induced intestinal injury by targeting GADD45B/TAOK1/p38 MAPK pathway.
Ginsenoside Rk3 Alleviates Neuroinflammation and Gastrointestinal Dysfunction in Parkinson's Disease via Modulation of Gut Microbiota-Mediated Butyric Acid Metabolism.
Artesunate promotes intestinal epithelial barrier repair by facilitating HMGCS2-dependent ketogenesis in experimental ulcerative colitis model mice.
Cardamonin alleviates intestinal inflammation in LPS-induced weaned piglets through the AhR/Nrf2/NLRP3 signaling pathway.
Palmatine ameliorates intestinal epithelial barrier injury in ulcerative colitis via targeting enolase 3.
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/NF-κB/MLCK/MLC signaling in ulcerative colitis.
Electroacupuncture suppresses motor impairments via microbiota-metabolized LPS/NLRP3 signaling in 6-OHDA induced Parkinson's disease rats.
Metal-Organic Framework-Remodeled Gut Microbiota Alleviates Colonic Inflammation via Selective Modulation of Roseburia intestinalis.
Chronic Exposure to Sunset Yellow Promotes Susceptibility to Experimental Colitis in Mice through Gut Microbiota.
Study on the mechanism of penetration of particles of air pollution into the brain through the nasal cavity and the potential neurological health risks.
The Fluidic Shear Stress Loading Method Enables Mechanobiological Stimulation in an On-Chip Pump-Integrated Microphysiological System.
Lactobacillus plantarum CCFM639 ameliorates vascular dysfunction in mice with Kawasaki disease involving eNOS/NO pathway.
Exposure to Bovine Viral Diarrhea Virus Disrupts Intestinal Barrier Function via NLRP3/Caspase-1-Mediated Pyroptosis and Gut Microbiota Dysbiosis.
Metformin limits cerebral cavernous malformation development by targeting KLF4-mediated mitochondrial damage.
Polyphyllin I enhances the anti-tumor efficacy of Palbociclib by reversing M2 macrophage polarization in lung cancer.
A phosphoproteomic study uncovers the importance of PP2A-B56α in liver injury precipitated by NLRP3 activation during MC-LR exposure.
Isoquercitrin mitigates intestinal ischemia-reperfusion injury by regulating intestinal flora and inhibiting NLRP3 inflammasome activation.
Dectin-1 Drives Diabetic Retinopathy via Inducing Microglia-Mediated Inflammation and Blood-Retinal Barrier Breakdown.
Disruption of Bile Acid Metabolism in the Gut-Liver Axis Predisposes Mice to Inflammatory Bowel Disease.
Overexpression of colonic VIP ameliorates cognitive function and barrier system damage caused by sevoflurane anesthesia and surgery in aged rats with fragile brain functions.
Outer membrane protein A mediates Klebsiella pneumoniae penetration of the blood-brain barrier and induces bacterial meningitis.
Genetical TRPV4 deletion-associated gut microbiota alleviates cardiac dysfunction in mice with diabetic cardiomyopathy.
Structural Variations in Ulcerative Colitis-associated Escherichia coli Reduce Fructose Utilization and Aggravate Inflammation Under High-Fructose Diet.
Maslinic acid alleviates ulcerative colitis by inhibiting the colitis-aggravating pathogen Clostridium perfringens and modulating gut microbiota.
Gastrodin ameliorates DSS-induced ulcerative colitis via enhancing the abundance of Akkermansia muciniphila and modulating the metabolites.
Endothelial Piezo1 Mediates Barrier Dysfunction and NLRP3 Inflammasomes Activation in Psoriasis.
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression.
Nod2 deficiency exacerbates schizophrenia-related alterations in offspring of maternal immune activation in a sex-dependent manner.
Intestinal Epithelial-Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78-mediated Endoplasmic Reticulum Stress.
Polygonatum sibiricum Polysaccharides Alleviate Simulated Weightlessness-Induced Cognitive Impairment by Gut Microbiota Modulation and Suppression of NLRP3/NF-κB Pathways.
The role of ROCK1/MLC/NMMHC IIA-actin signaling in ischemic stroke-induced blood-brain barrier disruption: implications for therapeutic intervention.
Hyocholic Acid Species as the Key Modulator for Cecal Epithelial Homeostasis in Low-Birth-Weight Piglets.
Rosmarinic acid improves intestinal barrier integrity through PI3K/AKT/Nrf2-mediated regulation of tight junction protein expression.
Neuronal pentraxin 1 accelerates post-stroke atherosclerosis by inducing endothelial cell senescence.
Lychee Fermented by Mixed Probiotic Strains Alleviates D-Galactose-Induced Skeletal Muscle and Intestinal Aging in Mice.
Green synthesized mesoporous silica nanoparticles offer a promising drug delivery system investigated in physiologically relevant 3D microfluidic models.
Preventive effects of sheep milk on DSS-induced colitis in mice: modulation of gut microbiota and inflammatory responses.
Double-Layered Microphysiological System Made of Polyethylene Terephthalate with Trans-Epithelial Electrical Resistance Measurement Function for Uniform Detection Sensitivity.
Targeting PLOD2 induces epithelioid differentiation and improves therapeutic response in sarcomatoid renal cell carcinoma.
Enhancement of Intestinal Barrier Function by Butyryl-Fructooligosaccharides via Microbiota-Host Interactions in Colonic Organoid Models.
Nicotinamide mononucleotide rescues Di-n-butyl phthalate induced blood-brain barrier damage via NAD(+)/Sirt1/FOXO1a pathway activation.
SOCS2 alleviates traumatic brain injury-induced mitochondrial damage and parthanatos in endothelial cells by inhibiting the JAK2/STAT3 signaling pathway.
Corynebacterium striatum drives neutrophilic asthma via IL-17 signaling activation.
Long noncoding RNA ENST00000458139 promotes mitochondrial dysfunction and apoptosis of podocytes in diabetic kidney disease through binding with SNRPA1.
Therapeutic effects of D-cycloserine in mouse models of IBD and CAC: Targeting NLRP3 inflammasome and intestinal barrier integrity.
Vitamin D Deficiency Exacerbates d-Galactose-Induced Intestinal Barrier Dysfunction in a Murine Model of Intestinal Aging.
Mechanism of silica nanoparticles induced pulmonary epithelial-mesenchymal transition mediated by exosomal HNRNPAB.
Developmental exposure to methyl ester sulfonate induces autism-like behavioral deficits in mice by dysregulation of the Notch/Hes signaling pathway disrupting neuronal differentiation.
OSBPL2 deficiency impaired cochlear blood-labyrinth barrier via activation of NF-κB signaling pathway.
Electroacupuncture at Baliao Points Attenuates Visceral Hypersensitivity in Irritable Bowel Syndrome via Gut-Microbiota-Mast Cell-TPRV1 Axis Modulation.
Regulatory effects of Ophiopogon japonicus polysaccharide on intestinal immune function in mice.
Oral absorption mechanisms of Astragalus polysaccharides and potential as an excipient to increase the absorption of flavonoids.
A High-Fat Diet Damages the Blood-Testis Barrier Through the PCSK9-LOX1 Positive Feedback Loop in Sertoli Cells.
The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs.
Silymarin ameliorates diet-induced gallstone formation by regulating gut microbiota-derived GCDCA to suppress ferroptosis-ROS-NFκB signaling pathway.
Macrophage NADPH oxidase inhibition by ultralow-dose dextromethorphan alleviates DSS-induced inflammation and colitis.
Neutrophil extravasation and NETosis in decompression illness lung injury: A P-selectin/PSGL-1/NOX2/PAD4 axis governed pathway validated by multi-model interrogation.
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation.
A novel off-liver sinusoidal progenitor cells in supporting transplantable bioliver engineering.
Vitamin D3 Improves Hypothalamic-Pituitary-Adrenal Axis Function, Immunological Responses, and Gut Dysbiosis in Sleep Desynchrony.
Fufang Huangqi Jianpi Oral Liquid alleviates spleen deficiency diarrhea via modulation of the NF-κB/Nrf2 signaling pathway and apoptosis.
Gut microbiota-bile acid metabolic disorder involved in the cognitive impairments in epilepsy through HO-1 dependent ferroptosis.
Yuzhi Zhixue Granules regulate the JAK/STAT pathway to affect T-cell differentiation in the colon of ulcerative colitis.
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Obacunone ameliorates high-fat diet-induced MAFLD by regulating the PPARγ-FABP1/CD36 axis and the gut-liver crosstalk.
Huaier overcomes tumor-induced immunosuppression in colorectal cancer by activating MHC I and CD8+ T cells.
Benzoylpaeoniflorin alleviates ulcerative colitis by inhibiting ferroptosis through targeting phosphogluconic dehydrogenase.
MicroRNA-93-5p alleviates uric acid-induced fibrosis in renal tubular epithelial cells by regulating the SMAD5/Id2 signaling pathway.
Bavachinin alleviates allergic rhinitis by modulating gut microbiota and inhibiting NLRP3-mediated epithelial pyroptosis through PI3K/AKT/NF-κB signaling pathway.
Octanoic Acid-Rich Enteral Nutrition Regulates Intestinal M1/M2 Macrophage Polarization via the PPARγ/STAT-1/STAT-6 Pathway to Alleviate Inflammatory Bowel Disease.
Megasphaera Elesdenii Dysregulates Colon Epithelial Homeostasis, Aggravates Colitis-Associated Tumorigenesis.
Effect of berberine on LPS-induced intestinal epithelial injury and m(6)A methylation in broilers.
Pgk1 activation restores endothelial metabolic homeostasis to alleviate vascular aging and atherosclerosis.
Phosphorylation of EF-P aggravates Streptococcus suis-induced blood-brain barrier damage by enhancing serine protease production.
Streptozotocin Causes Blood-Brain Barrier and Astrocytic Dysfunction In Vitro.
Atorvastatin improves spermatogenesis in murine and in vitro human chronic orchitis models through restoring blood-testis barriers.
Unveiling the gut-vascular connection: Gut microbiota regulates cardiovascular toxicity induced by combined exposure to PM(2.5) and high-fat diet via butyric acid/NLRP3 pathway.
Dexmedetomidine enhances anastomotic healing partly via the Wnt/β-catenin pathway in a rat model of colon surgery.
Bifidobacterium animalis subsp. lactis GOLDGUT-BB69 Counteracts Diarrhea in Mice by Alleviating Inflammation, Enhancing Intestinal Barrier Functions, and Regulating Intestinal Microbiota.
Er Miao San Attenuates Collagen-Induced Arthritis Mice by Regulating Gut Microbiota and Its Metabolites.
Loss of alpha-kinase 1 contributes to the formation of congenital cataracts in mice.
FABP3 Mediates Lipid Droplet Accumulation and Adhesive Capacity in Bovine Endometrial Epithelial Cells via PGE(2)/PTGER4/PPAR Axis.
Methylene blue reduces postoperative delirium in mice through neuroinflammation suppression and blood-brain barrier repair.
Huang-Lian-Jie-Du decoction alleviates diabetic ischemic stroke by modulating gut microbiota-derived short-chain fatty acids.
Tongxie Yaofang attenuates ulcerative colitis by modulating gut microbiota and IL-10RA/NF-κB-mediated macrophage polarization.
Zexieyin formula attenuates Alzheimer's disease via suppressing A1 astrocyte activation: A serum pharmacochemistry and network pharmacology study.
Oxymatrine ameliorates ulcerative colitis via improving epithelial barrier function through targeting DSG2.
Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by attenuating the malignancy of cancer stem cells via the gut microbiota-bile acid-FXR axis.
Xinqingning tablet attenuates ischemic stroke complicated by gut dysbiosis through regulating the miR-126-driven gut-brain axis.
Genkwanin reduces airway epithelial cell ferroptosis and alleviates asthma symptoms in mice.
Farrerol alleviates microbiota dysbiosis-associated osteoporosis in IBD by inhibiting PI3K-AKT/MAPK signaling pathways.
PD-L1(+) neutrophils trigger pulmonary endothelial pyroptosis via an oxidative phosphorylation-dependent mechanism in sepsis.
Activation of the aryl hydrocarbon receptor relieves acute pancreatitis via the RBX1/HSF1 pathway.
Gut Microbiota-Targeted Photobiomodulation Ameliorates Alzheimer's Pathology via the Gut-Brain Axis: Comparable Efficacy to Transcranial Irradiation.
Fatty Acid-binding Protein 4 Exacerbates Blood-brain Barrier Disruption Through the JNK/c-Jun/MMP12 Pathway After Traumatic Brain Injury.
Autism-Associated Gut Microbiota-Derived Enterococcus facium Modulates Gut-Brain Axis Function and Behavior in Mice.
Downregulation of oar-miR-125b Drives Blood-Brain Barrier Breakdown Through the TNFSF4-NF-κB Inflammatory Axis in Enterococcus Faecalis Meningitis.
Curcumin Alleviates Bisphenol A-Induced Blood-Testis Barrier Disruption in Mice by Targeting Surfactant Protein B (SFTPB) to Suppress Oxidative Stress-Activated NLRP3 Inflammasome.
Engineering Escherichia coli nissle 1917 with lactonase ZHD101 alleviates zearalenone-induced intestinal disruption and reproductive toxicity in rat.
Migration of CD8 + TSCM cells into intestine via PPBP-CXCR2 axis increases host stress susceptibility by inhibiting gut microbiome-derived homovanillic acid.
Dysregulated ITGA3/FAK/YAP axis mediates impaired alveolar type II epithelial cells function in COPD.
Human umbilical cord mesenchymal stromal cell-derived exosomes alleviate antibiotic-induced intestinal barrier damage by regulating autophagy via the S100G/mTOR signaling pathway.
Fusobacterium nucleatum-derived extracellular vesicles carrying virulence factor DNA trigger AIM2 inflammasome activation to facilitate UC progression.
Berberine ameliorates high-fat diet-induced metabolic disorders through promoting gut Akkermansia and modulating bile acid metabolism.
Thymosin β4 released by mast cells under stress conditions impairs intestinal epithelial barrier via IL22RA1/JAK1/STAT3 signaling in irritable bowel syndrome.
Alterations in Gut Microbiota and their Association with Colonic Permeability and Inflammation in LPS-induced Sepsis Mice.
Disulfiram Prevents Blood-Brain Barrier Disruption in Epileptic Mice by Inhibiting Astrocyte Pyroptosis to Improve Seizure Activity.
Tetrandrine enhances cognition in SAH rats via gut microbiota CYP51 and TLR4 signaling.
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Folate Attenuates Ulcerative Colitis via PI3K/AKT/NF-κB/MLCK Axis Inhibition to Restore Intestinal Barrier Integrity.
Integrated multi-omics of gut-liver axis to dissect the mechanism underlying hepatotoxicity induced by sub-chronic tire wear particles exposure in mice.
Hydroxysafflor yellow A attenuates the blood-brain barrier dysfunction and neuroinflammation through anti-inflammatory microglial polarization after intracerebral hemorrhage.
Neuroprotective effects of urolithin a in a mouse model of intracerebral hemorrhage.
Large-scale multi-trait genome-wide analysis for inflammatory bowel disease reveals new insights into its molecular mechanisms and emphasizes the roles of systemic immune regulation.
Gut flora-derived succinate exacerbates Allergic Airway Inflammation by promoting protein succinylation.
HIF-1α Enhances Intestinal Injury and Inflammation in Severe Acute Pancreatitis Through NLRP3 Inflammasome Activation.
Effects of Narrowband Ultraviolet B Therapy on the Skin Barrier in a Murine Model of Dry Skin.
Forsythiaside A Alleviates Ulcerative Colitis and Inhibits Neutrophil Extracellular Traps Formation in the Mice.
Gastrodin Ameliorates Tau Pathology and BBB Dysfunction in 3xTg-AD Transgenic Mice by Regulating the ADRA1/NF-κB/NLRP3 Pathway to Reduce Neuroinflammation.
Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy.
Dietary supplementation of yeast polysaccharides enhance lamb growth performance by improving immune and intestinal barrier function and the abundance of cecal microbiota.
Larimichthys crocea isinglass polysaccharide attenuates DSS-induced colitis via gut microbiota regulation and NF-κB signaling inhibition.
Kai-Xin-San polysaccharides exert therapeutic effects on D-gal and Aβ(25)(-)(35)-induced AD rats by regulating gut microbiota and metabolic profile.
β-1,3-glucans from Euglena Gracilis protects against ulcerative colitis via modulating the gut barrier, T-cell immunity and gut microbiota.
The ferroptosis of sertoli cells inducing blood-testis barrier damage is produced by oxidative stress in cryptorchidism.
Synergistic effects of the Aβ/fibrinogen complex on synaptotoxicity, neuroinflammation, and blood-brain barrier damage in Alzheimer's disease models.
Kaempferol promotes angiogenesis through HIF-1α/VEGF-A/Notch1 pathway in ischemic stroke rats.
IL-33 facilitates endoplasmic reticulum stress and pyroptosis in LPS-stimulated ARDS model in vitro.
Puerarin improves MASLD by remodeling intestinal microenvironment to promote mitochondrial fusion and autophagy.
Odd-Chain Fatty Acid-Enriched Fats Improve Growth and Intestinal Morphology and Function in Milk Replacer-Fed Piglets.
Three-Dimensional Dynamic Blood-Brain Barrier Model Incorporating Native Cell Culture Systems Based on Shape Memory Biomaterials.
A perfused iPSC-derived proximal tubule model for predicting drug-induced kidney injury.
Compound probiotics alleviate hyperuricemia-induced renal injury via restoring gut microbiota and metabolism.
Heterophyllin B alleviates cognitive disorders in APP/PS1 model mice via the spleen-gut microbiota-brain axis.
Chestnut Nonstarch Polysaccharides Enhance Intestinal Barrier Integrity and Modulate Gut Microbiota to Ameliorate DSS-Induced Colitis in Mice.
Drinking Water Temperature Impacts the Pathogenesis of DSS-Induced Ulcerative Colitis by Regulating Intestinal Barrier Function and Remodeling the Gut Microbiota Composition.
Insulin/PHMB-grafted sodium alginate hydrogels improve infected wound healing by antibacterial-prompted macrophage inflammatory regulation.
In vivo keratotomy by mid-infrared femtosecond laser resonant with amide vibrational mode.
Uncovering the molecular mechanisms of tonifying kidney and activating blood Decoction against myocardial fibrosis using network Pharmacology and experimental validation.
Atractylenolide-1 Alleviates Ulcerative Colitis via Restraining RhoA/ROCK/MLC Pathway-Mediated Intestinal Barrier Dysfunction.
Network-based pharmacological and experimentally validated study on the therapeutic effects and mechanisms of Polygonatum Rhizoma Ginseng Formula in immunocompromised mice.
Schisandra chinensis lignans ameliorate hepatic inflammation and steatosis in methionine choline-deficient diet-fed mice by modulating the gut-liver axis.
Potential mechanisms by which Jiawei Lianpu Yin inhibits Helicobacter pylori colonization and alleviates gastric mucosal inflammation and damage: Integrated transcriptomics, network pharmacology, and experimental validation.
Semaglultide targets Spp1(+) microglia/macrophage to attenuate neuroinflammation following perioperative stroke.
ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity.
Pre-ischaemic empagliflozin treatment attenuates blood-brain barrier disruption via β-catenin mediated protection of cerebral endothelial cells.
Probiotics may not adhere to gut and provide benefits in inflammatory bowel disease patients based on an AOM/DSS murine model.
NUDT1 aggravates intestinal epithelial barrier injury through oxidative stress in ulcerative colitis.
IL-17 enhanced the susceptibility to fluoxetine resistance in depression via the JAK1-STAT6 signaling pathway.
Polygonatum cyrtonema Hua polysaccharide alleviates ulcerative colitis via gut microbiota-independent modulation of inflammatory immune response.
Engineered probiotics remodel the intestinal epithelial barrier and enhance bacteriotherapy for inflammatory bowel diseases.
Edaravone dexborneol provides neuroprotective benefits by suppressing ferroptosis in experimental intracerebral hemorrhage.
Bufei Yishen formula alleviates airway epithelial cell senescence in COPD by activating AMPK-Sirt1-FoxO3a pathway and promoting autophagy.
Transcriptomic analysis and experiment to verify the mechanism of Xiaoyao san in the treatment of irritable bowel syndrome with depression.
Exploring the mechanism of Sinisan in the treatment of ulcerative colitis with depression based on UPLC-Q-Orbitrap-MS combined with network pharmacology, molecular docking, and experimental validation.
Enteroendocrine cells regulate intestinal barrier permeability.
Depletion of Acetyl-CoA Carboxylase 1 Facilitates Epithelial-Mesenchymal Transition in Prostate Cancer Cells by Activating the MAPK/ERK Pathway.
A derivative of tanshinone IIA and salviadione, 15a, inhibits inflammation and alleviates DSS-induced colitis in mice by direct binding and inhibition of RIPK2.
Inhibition of histamine receptor 3 alleviates sevoflurane-induced hypomyelination and neurobehavioral deficits.
TSG-6 Protects Against Cerebral Ischemia-Reperfusion Injury via Upregulating Hsp70-1B in Astrocytes.
A high cholesterol diet aggravates experimental colitis through SREBP2-modulated endocytosis and degradation of occludin and Zo-1 proteins.
The impact of combined thymol and rosmarinic acid on the intestinal microbiota and barrier function of the piglets challenged by Escherichia coli K88.
Butylphthalide may inhibit blood-brain barrier disruption through complement-related pathways to alleviate cognitive impairment in epileptic mice.
Colon-Targeted Ginseng Polysaccharides-Based Microspheres for Improving Ulcerative Colitis via Anti-Inflammation and Gut Microbiota Modulation.
Elevated SPARC Disrupts the Intestinal Barrier Integrity in Crohn's Disease by Interacting with OTUD4 and Activating the MYD88/NF-κB Pathway.
Intestine-Decipher Engineered Capsules Protect Against Sepsis-induced Intestinal Injury via Broad-spectrum Anti-inflammation and Parthanatos Inhibition.
The Gut Microbiota-Xanthurenic Acid-Aromatic Hydrocarbon Receptor Axis Mediates the Anticolitic Effects of Trilobatin.
The shared mechanism of barrier dysfunction in ulcerative colitis and Alzheimer's disease: DDIT4/IL1β neutrophil extracellular traps drive macrophages-mediated phagocytosis.
TEPP-46 inhibits glycolysis to promote M2 polarization of microglia after ischemic stroke.
SVHRSP protects against rotenone-induced neurodegeneration in mice by inhibiting TLR4/NF-κB-mediated neuroinflammation via gut microbiota.
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Neutrophil-derived heparin-binding protein increases endothelial permeability in acute lung injury by promoting TRIM21 and the ubiquitination of P65.
Edaravone dextranol alleviates ferroptosis, Cuproptosis, and blood-brain barrier damage after acute cerebral infarction.
Houshiheisan modulates the NF-κB/MLCK signaling pathway to protect the endothelial barrier in cerebral small vessel disease.
Sensor-integrated gut-on-a-chip for monitoring senescence-mediated changes in the intestinal barrier.
The dopamine receptor agonist rotigotine attenuated indomethacin-induced enteropathy in the small intestinal mucosa of mice.
Dietary emulsifier carboxymethylcellulose-induced gut dysbiosis and SCFA reduction aggravate acute pancreatitis through classical monocyte activation.
Fisetin alleviates Salmonella typhimurium-induced colitis through the TLR2/TLR4-NF-κB pathway, regulating microbiota, and repressing intracellular bacterial proliferation by focal adhesion kinase.
Intranasal Delivery of Hydrophobic AC5216 Loaded Nanoemulsion into Brain To Alleviate Chronic Unpredictable Stress-Induced Depressive-like Behaviors.
Shengui Sansheng San alleviates the worsening of blood-brain barrier integrity resulted from delayed tPA administration through VIP/VIPR1 pathway.
Probiotic Delivery for Editing of the Gut Microbiota to Mitigate Colitis and Maintain Hepatic Homeostasis Via Gut-Liver Axis.
Vitamin A-Integrated Cinnamaldehyde Nanoemulsion: A Nanotherapeutic Approach To Counteract Liver Fibrosis via Gut-Liver Axis Modulation.
Heat-killed Lacticaseibacillus paracasei 6235 is more effective than live on DSS-induced colitis via modulation of intestinal microbiota and MAPK/NF-κB signaling pathways.
Target inhibition of SPAK in choroid plexus attenuates T cell infiltration and demyelination in experimental autoimmune encephalomyelitis.
Supplementary Hesperidin Alleviated CPT-11-Induced Diarrhea by Modulating Gut Microbiota and Inhibiting the IL-17 Signaling Pathway.
Oleanolic Acid Alleviates Hyperuricemia via Gut Microbiota Control the Integrity of Gut Barrier and the Expressions of Urate Transporter in Mice.
Hawthorn Pectin Alleviates DSS-Induced Colitis in Mice by Ameliorating Intestinal Barrier Function and Modulating Gut Microbiota.
Evaluation of Perfusion Cell Culture Conditions in a Double-Layered Microphysiological System Using AI-Assisted Morphological Analysis.
Enteroendocrine Cells Regulate Intestinal Barrier Permeability.
Why do microplastics aggravate cholestatic liver disease? The NLRP3-mediated intestinal barrier integrity damage matter.
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
Bidirectional transport studies of flavonoids from Alpiniae oxyphyllae fructus by in vitro inflammatory blood-brain barrier model combined with UHPLC-MS/MS analysis.
Respiratory Syncytial Virus Infection Disrupts Airway Epithelial Barriers via IL-33/ST2/MyD88 Signaling Axis.
Low-intensity pulsed ultrasound irradiation ameliorates gut inflammation and neuroinflammation in mice with DSS-induced colitis.
H3K18 lactylation-mediated SIX1 upregulation contributes to silica-induced epithelial-mesenchymal transition in airway epithelial cells.
Effect of low humidity on the barrier functions of keratinocytes in a reconstructed human epidermal model.
Dual-modality ultrasound/photoacoustic tomography for mapping tissue oxygen saturation distribution in intestinal strangulation.
β-Sitosterol Ameliorates Ulcerative Colitis Through Modulation of the AMPK/MLCK Anti-Inflammatory Pathway.
Bioinspired hydrogel for sustained minocycline release: A superior periodontitis solution.
Sanghuangporus vaninii polysaccharides alleviates the effects of chlorpyrifos exposure on mouse liver: role of the gut- liver axis.
Rehmannia glutinosa polysaccharides alleviate cyclophosphamide-induced immunosuppression by enhancing immunity and restoring intestinal homeostasis.
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
Aging-associated intestinal dysfunction impairs 5-heptadecylresorcinol absorption: Mechanistic insights into transporter-mediated uptake, barrier integrity and inflammatory regulation.
Visualizing androgen signaling and assessing its interaction with canonical Wnt signaling pathways in prostate development, morphogenesis, and regeneration.
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance.
Acupuncture regulates astrocyte neurotoxic polarization to protect blood-brain barrier integrity in delayed thrombolysis through mediating ERK1/2/Cx43 axis.
An anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut-lung axis and NLRP3 inflammasome activation.
Protective effects of albiflorin on acetaminophen-induced hepatotoxicity: Regulation of blood-biliary barrier integrity by ATF3.
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Oleic acid regulates CD4+ T cells differentiation by targeting ODC1-mediated STAT5A phosphorylation in Vogt-Koyanagi-Harada disease.
Huang-Lian-Jie-Du decoction inhibits CD4+ T cell infiltration into CNS in MCAO rats by regulating BBB.
Dimethyl Itaconate Alleviates Escherichia coli-Induced Endometritis Through the Guanosine-CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae.
CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1-Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis.
Long non-coding RNA ANRIL/p65 negative feedback loop protects intestinal barrier function in inflammatory bowel disease.
Glutamine Attenuates Inflammation and Oxidative Stress in Ulcerative Colitis by Suppressing Wilms' Tumor 1 Associated Protein-Mediated N6-Methyladenosine Modification of Nuclear Receptor Coactivator 3.
Investigation of postmortem change in the human corneal epithelium via impression cytology.
Probiotic Combination of Limosilactobacillus fermentum HF07 and Lactococcus lactis HF08 Targeting Gut Microbiota-Secondary Bile Acid Metabolism Ameliorates Inflammation and Intestinal Barrier Dysfunction in Aging Colitis.
Enhancing intestinal epithelial microtubule stability could alleviate IBD symptoms.
Sesamin improved growth and overall health in young animals by enhancing gut-liver axis function.
Piezo1 disrupts blood-brain barrier via CaMKII/Nrf2 in ischemic stroke.
Disulfiram alleviates epithelial barrier disruption in ozone-induced chronic obstructive pulmonary disease mouse models via inhibiting Gasdermin D-mediated pyroptosis.
Circ-0000197 derived from porcine milk small extracellular vesicles promotes intestinal barrier function by sponging miR-429.
Photobiomodulation mitigates blood-brain barrier disruption in APP/PS1 mouse model of Alzheimer's disease by activating the AMPK pathway.
Endothelial cell Nrf2 controls neuroinflammation following a systemic insult.
Excretory/secretory products from Hymenolepis nana adult worms alleviate ulcerative colitis in mice via tuft/IL-13 signaling pathway.
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Idebenone Orchestrates Anti-Inflammatory and Antioxidant Responses to Alleviate Brain Injury After Intracerebral Hemorrhage in Mice.
Liver-Skin Microphysiological System for Evaluating Topical Drug Delivery-Induced Liver Injury.
Polystyrene nanoplastics aggravate house dust mite induced allergic airway inflammation through EGFR/ERK-dependent lung epithelial barrier dysfunction.
Transcranial magnetic stimulation through attenuating blood-spinal cord barrier disruption and reducing inflammatory response to improve motor function in rats with spinal cord injury.
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Integrating transcriptomics, metabolomics, and microbiomics to explore the mechanism of action of bran-fried Atractylodes lancea rhizome polysaccharide in ameliorating the enhanced pharmacological effects of dextran sodium sulfate-induced colitis.
The Effects of Pretreated and Fermented Corn Stalks on Growth Performance, Nutrient Digestion, Intestinal Structure and Function, and Immune Function in New Zealand Rabbits.
Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.
Comparison of Efavirenz and Dolutegravir on Gut Microbiome and Gut Barrier Functions.
PCP protein Prickle 1 regulates Sertoli cell and testis function via cytoskeletal organization through the recruitment of multiple regulatory proteins.
KLF10 Induced by Hypothermic Machine Perfusion Alleviates Renal Inflammation Through BIRC2 /Noncanonical NF-κB Pathway.
Probiotic domestication and engineering enable one-shot treatment for bladder mucosal repair.
Xuefu Zhuyu Decoction Improves Blood-Brain Barrier Integrity in Acute Traumatic Brain Injury Rats via Regulating Adenosine.
Ethanolic Extract of Atractylodis Rhizoma Ameliorates DSS-Induced Ulcerative Colitis via Improving Intestinal Barrier Function Through the Rho-Associated Kinase/Myosin Light Chain Pathway.
RETRACTED ARTICLE: Copper Exposure Destroys the Integrity of the Blood-Testis Barrier (BTB) Through p38 MAPK-Meditated Autophagy Pathways.
Andrographolide and its sulfated metabolite alleviated DSS-induced inflammatory bowel disease through regulating inflammation and immune via MAPK/NLRP3 pathways and the balance of Th17/Treg cells.
Acupuncture Alleviates Blood-Brain Barrier Damage After Delayed rtPA Thrombolysis for Acute Ischemic Stroke by Regulating Ferroptosis.
Echinacoside alleviates type 2 diabetes mellitus through inhibiting hepatic gluconeogenesis via gut bacterial-fungal trans-kingdom network reconstruction.
Crataegus pinnatifida polysaccharide alleviates DSS-induced colitis in mice by regulating the intestinal microbiota and enhancing arginine biosynthesis.
Music intervention mitigates LPS-induced gut barrier disruption and immune stress in broilers via TLR4/NF-κB regulation.
ORF3a is a key driver of maternal SARS-CoV-2 infection-associated placental dysfunction.
Endoplasmic reticulum-mitochondria coupling prompts ZBP1-mediated RPE cell PANoptosis in age-related macular degeneration.
An engineered antimicrobial peptide Z-FV7 demonstrates bactericidal efficacy against multidrug-resistant Escherichia coli in a murine model of endometritis.
Platelet-derived microparticles increase the interaction of colorectal cancer cells with the endothelium to promote metastatic events.
The promoting effect of high-fat diet-induced trained immunity on ulcerative colitis and the mechanism of the therapeutic effect of Dahuang Mudan Decoction.
Poliumoside alleviates microglia-mediated inflammation and blood-brain barrier disruption via modulating the polarization of microglia after ischemic stroke in mice.
Nuciferine ameliorates blood-brain barrier disruption post-ischemic stroke via inhibiting the JAK2/STAT3 pathway.
Qingshu Yiqi decoction ameliorates exertional heat stroke-induced intestinal barrier injury via NF-κB/MLC pathway and gut microbiota.
PEAK1 maintains tight junctions in intestinal epithelial cells and resists colitis by inhibiting autophagy-mediated ZO-1 degradation.
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice.
Calcium transients regulate the apical emergence of basally located progenitors during Xenopus skin development.
Exploring the Mechanism of Kidney Injury in Mice Induced by High-Fat Diet and Polystyrene Nanoplastics Co-Exposure Through the Kidney-Gut Axis.
Engineered Exosomes Delivering bta-miR-223 Alleviate Staphylococcus aureus-Induced Mastitis in Mice via the TLR4/NF-κB Signaling Pathway.
Lyophilized apoptotic vesicles restore DNA damage and mitochondria dysfunction to ameliorate radiation enteritis.
Long term chlorantraniliprole exposure induced intestinal and cognitive impairment via inducing lipid and amino acid metabolism dysfunction.
Peptide Cy(RL-QN15) alleviates UVB-induced skin aging by promoting the repair of barrier.
Kushenol I combats ulcerative colitis via intestinal barrier preservation and gut microbiota optimization.
Targeting modulation of the choroid plexus blood-CSF barrier and CSF hypersecretion via lipid nanoparticle-mediated co-delivery of siRNA and resveratrol.
Low-dose polystyrene microplastics exposure increases susceptibility to obesity-induced MASLD via disrupting intestinal barrier integrity and gut microbiota homeostasis.
α7 nicotinic acetylcholine receptors regulate radial glia fate in the developing human cortex.
Cold environment regulates ischemic stroke through modulation of gut microbiota.
Ferroptosis is involved in the IL-9-induced intestinal barrier injury in sepsis: an experimental animal and translational study.
Butyrate protects the intestinal barrier by upregulating Fut2 expression via MEK4-JNK signaling pathway activation.
Wolfberry Honey and Its Extract Alleviate Dextran Sodium Sulfate-Induced Ulcerative Colitis by Improving Intestinal Barrier Function and Reducing Oxidative Stress and Inflammation.
Astrocytes-Secreted WNT5B Disrupts the Blood-Brain Barrier Via ROR1/JNK/c-JUN Cascade During Meningitic Escherichia Coli Infection.
Slit2 Promotes H(2)O(2)-Induced Lens Epithelial Cells Oxidative Damage and Age-Related Cataract.
Characteristics of polycystic ovary syndrome rat models induced by letrozole, testosterone propionate and high-fat diets.
Biased constitutive signaling of the G protein-coupled receptor GPR35 suppresses gut barrier permeability.
Astragalus polysaccharide alleviates mastitis disrupted by Staphylococcus aureus infection by regulating gut microbiota and SCFAs metabolism.
Verteporfin combined with ROCK inhibitor promotes the restoration of corneal endothelial cell dysfunction in rats.
Discovery of a novel AhR-CYP1A1 axis activator for mitigating inflammatory diseases using an in situ functional imaging assay.
Pimpinellin mitigates DSS-induced ulcerative colitis in mice by reducing inflammation and regulating gut microbiota.
Toosendanin alleviates acute lung injury by reducing pulmonary vascular barrier dysfunction mediated by endoplasmic reticulum stress through mTOR.
Dachengqi decoction ameliorated liver injury in liver fibrosis mice by maintaining gut vascular barrier integrity.
C9orf72 Alleviates DSS‑Induced Ulcerative Colitis via the cGAS-STING Pathway.
Supervillin-Mediated ZO-1 Downregulation Facilitates Migration of Cisplatin-Resistant HCT116 Colorectal Cancer Cells.
Luteolin Alleviates Ulcerative Colitis in Mice by Modulating Gut Microbiota and Plasma Metabolism.
Ubiquitin-specific protease 25 ameliorates ulcerative colitis by regulating the degradation of phosphor-STAT3.
GYY4137 ameliorates blood brain barrier damage by inhibiting autophagy mediated occludin degradation in cardiac arrest and resuscitation.
Intestinal Barrier Damage and Growth Retardation Caused by Exposure to Polystyrene Nanoplastics Through Lactation Milk in Developing Mice.
Dihydromyricetin attenuates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating oxidative stress and inhibiting NLRP3 inflammasome.
YiMu-QingGong san alleviates lipopolysaccharide-induced endometritis in mice via inhibiting inflammation and oxidative stress through regulating macrophage polarization.
Ursodeoxycholic acid protects against sepsis-induced acute kidney injury by activating Nrf2/HO-1 and inhibiting NF-κB pathway.
Mechanistic study of the effect of a high-salt diet on the intestinal barrier.
Cecropin AD ameliorates pneumonia and intestinal injury in mice with mycoplasma pneumoniae by mediating gut microbiota.
Co-exposure to polyethylene microplastics and house dust mites aggravates airway epithelial barrier dysfunction and airway inflammation via CXCL1 signaling pathway in a mouse model.
Interleukin 8 exacerbates age-related hearing loss through regulating perivascular-resident macrophage-like melanocytes viability and the permeability of the endothelial cells.
Lentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice.
Let-7f-5p/AIMP1/ZO-1 axis mediates blood-brain barrier dysfunction in neuromyelitis optica spectrum disorders.
Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction.
Lactobacillus rhamnosus LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by inhibiting the TLR9/NF-κB signaling pathway.
Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners.
Multi-omics analysis and experimental verification reveal testicular fatty acid metabolism disorder in non-obstructive azoospermia.
Peptide-drug conjugates repolarize glioblastoma-associated macrophages to resensitize chemo-immunotherapy of glioblastoma.
Exploring the Underlying Mechanism of Weiling Decoction Alleviates Cold-Dampness Diarrhea Based on Network Pharmacology, Transcriptomics, Molecular Docking and Experimental Validation.
Ganoderic Acid A Alleviates Severe Acute Pancreatitis by Modulating Gut Homeostasis and Inhibiting TLR4-NLRP3 Signaling.
The Role of TRPV1/CGRP Pathway Activated by Prevotella melaninogenica in Pathogenesis of Oral Lichen Planus.
Neohesperidin Mitigates High-Fat-Diet-Induced Colitis In Vivo by Modulating Gut Microbiota and Enhancing SCFAs Synthesis.
The efficacy and active compounds of Chaihuang Qingyi Huoxue granule to Ameliorate intestinal mucosal barrier injury in rats with severe acute pancreatitis by suppressing the HMGB1/TLR4/NF-κB signaling pathway.
Selenoprotein M protects cardiac endothelial cell integrity against high-glucose stress via enhancing Parkin-mediated mitophagy.
Bisphenol S exposure promotes stemness of triple-negative breast cancer cells via regulating Gli1-mediated Sonic hedgehog pathway.
SPHK1/S1PR1/PPAR-α axis restores TJs between uroepithelium providing new ideas for IC/BPS treatment.
Therapeutic Potential of Vanillic Acid in Ulcerative Colitis Through Microbiota and Macrophage Modulation.
Inhibition of miR-142-3p promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury by targeting FoxM1.
N-Acetylcysteine Alleviates Necrotizing Enterocolitis by Depressing SESN2 Expression to Inhibit Ferroptosis in Intestinal Epithelial Cells.
Activation of PPARγ regulates M1/M2 macrophage polarization and attenuates dextran sulfate sodium salt-induced inflammatory bowel disease via the STAT-1/STAT-6 pathway.
Lysosome-Targeting Protein Degradation Through Endocytosis Pathway Triggered by Polyvalent Nano-Chimera for AD Therapy.
Geniposide Protects Against Myocardial Infarction Injury via the Restoration in Gut Microbiota and Gut-Brain Axis.
Single-Cell Transcriptomic Reveals the Involvement of Cell-Cell Junctions in the Early Development of Hypertrophic Cardiomyopathy.
Effects of exopolysaccharides form Lactobacillus plantarum KX041 on high fat diet-induced gut microbiota and inflammatory obesity.
A comparative study on in vitro models of necrotizing enterocolitis induced by single and combined stimulation.
Muribaculum intestinale-derived 3-hydroxybutyric acid from Heterophyllin B attenuated pulmonary fibrosis through IDO1-mediated ferroptosis.
Discovery of anti-inflammatory molecules from Dendrobium officinale based on activity labelled molecular networking and its alleviation effect on ulcerative colitis.
Xylooligosaccharide and Akkermansia muciniphila synergistically ameliorate insulin resistance by reshaping gut microbiota, improving intestinal barrier and regulating NKG2D/NKG2DL signaling in gestational diabetes mellitus mice.
Long-term effects of Nε-carboxymethyllysine intake on intestinal barrier permeability: Associations with gut microbiota and bile acids.
Lactobacillus acidophilus JYLA-126 Ameliorates Obesity-Associated Metabolic Disorders by Positively Regulating the AMPK Signaling Pathway Through the Gut-Liver Axis.
Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model.
Transcriptomic analysis of key genes and signaling pathways in sepsis-associated intestinal mucosal barrier damage.
Mannuronate Oligosaccharides Ameliorate Experimental Colitis and Secondary Neurological Dysfunction by Manipulating the Gut-Brain Axis.
TRIM37 exacerbates cerebral ischemic injury by regulating the PPARγ/NF-κB pathway.
Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice.
Oridonin Preserves Retinal Pigmented Epithelial Cell Tight Junctions and Ameliorates Choroidal Neovascularization.
An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice.
Lactate-triggered histone lactylation contributes to podocyte epithelial-mesenchymal transition in diabetic nephropathy in mice.
HMGB1 mediates epithelial-mesenchymal transition and fibrosis in silicosis via RAGE/β-catenin signaling.
Transcriptomics insights into glutamine on repairing of histamine-induced Yak rumen epithelial cells barrier damage in vitro.
Notch/IL33/ST2 signaling was involved in the maintenance of intestinal epithelial barrier through regulating tight junction after LPS stimulation.
House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK/AP-1/IL-24 Signaling pathway in allergic rhinitis.
NINJ1-mediated plasma membrane rupture of pyroptotic endothelial cells exacerbates blood-brain barrier destruction caused by neutrophil extracellular traps in traumatic brain injury.
L-Theanine Mitigates Acute Alcoholic Intestinal Injury by Activating the HIF-1 Signaling Pathway to Regulate the TLR4/NF-κB/HIF-1α Axis in Mice.
Bioactive nanomotor enabling efficient intestinal barrier penetration for colorectal cancer therapy.
FADS1 inhibition protects retinal pigment epithelium cells from ferroptosis in age related macular degeneration.
Treatment of Acute Ulcerative Colitis with Zinc Hyaluronate in Mice.
Effect of Food Matrix on Regulation of Intestinal Barrier and Microbiota Homeostasis by Polysaccharides Sulfated Carrageenan.
The bitter flavor of Banxia Xiexin decoction activates TAS2R38 to ameliorate low-grade inflammation in the duodenum of mice with functional dyspepsia.
Decreasing β-Catenin Leads to Altered Endothelial Morphology, Increased Barrier Permeability and Cognitive Impairment During Chronic Methamphetamine Exposure.
Functional evaluation of novel compound heterozygous variants in SLC12A3 of Gitelman syndrome.
The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression and after artemisinin treatment.
Magnolol preserves the integrity of the intestinal epithelial barrier and mitigates intestinal injury through activation of PPAR γ in COPD rat.
PRDM16 Induces Methylation of FLT3 to Promote FLT3-ITD Signaling and Leukemia Progression.
Polysaccharides from Lycium barbarum, yam, and sunflower ameliorate colitis in a structure and intrinsic flora-dependent manner.
Selenoproteome depletion enhances oxidative stress and alters neutrophil functions in Citrobacter rodentium infection leading to gastrointestinal inflammation.
Dihydroartemisinin Alleviates Ulcerative Colitis via Target Identification and Pathway Modulation: A Cyberpharmacology Approach.
Neoagarotetraose Attenuates Hyperglycemia Through Inflammation Amelioration and Glucose Metabolism Improvement.
Vasoactive intestinal peptide reduces ocular hypertension by regulating tight junction of trabecular meshwork through Rab13/PKA signalling complex.
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Activation of the liver X receptor α protects the blood-brain barrier against heatstroke-induced injury.
EUK nanozyme-loaded PL&GA coacervate droplets attenuate ulcerative colitis through restoring gut homeostasis and restricting intestinal cell ferroptosis.
Probiotic-based self-crosslinking bio-coating for the treatment of colitis by increasing probiotic colonization.
Engineering micelles with hydrophilic-lipophilic balance to overcome intestinal barrier for oral therapeutic application.
Atractylodin inhibits ferroptosis in sepsis‑induced acute gastrointestinal injury via SIRT3/PRDX3.
Apelin-13 Attenuates Blood-Brain Barrier Dysfunction Following Intracerebral Hemorrhage via Targeting the Keap1/Nrf2 Signaling.
Macrophage extracellular traps impair intestinal barrier function in DSS-induced colitis in mice by inducing intestinal epithelial cell apoptosis.
Co-fermentation of honeysuckle-Cassia seeds by Lactobacillus acidophilus and Bacillus subtilis: A new approach to attenuate alcohol-induced acute gastric mucosal damage and modulate immune response.
Nano Zinc Oxide Restores Gut Barrier Integrity and Modulates Microbiota to Mitigate TNBS-Induced Colitis in Mice.
Lactobacillus delbrueckii Alleviate Oxidative Stress and Intestinal Injuries by Activating TLR2 and TLR4 Expressions in IPEC-J2 Cells.
Lachnospiraceae bacterium alleviates alcohol-associated liver disease by enhancing N-acetyl-glutamic acid levels and inhibiting ferroptosis through the KEAP1-NRF2 pathway.
Upregulation of Lactobacillus spp. in gut microbiota as a novel mechanism for environmental eustress-induced anti-pancreatic cancer effects.
Novel role of FTO in regulation of gut-brain communication via Desulfovibrio fairfieldensis-produced hydrogen sulfide under arsenic exposure.
Neutrophil extracellular trap-borne C3-driven endothelial dysfunction in Klebsiella pneumoniae liver abscess.
The T-type voltage-gated Ca(2+) channel Ca(V)3.1 involves in the disruption of respiratory epithelial barrier induced by Pasteurella multocida toxin.
Endothelial NLRP3-mediated pyroptosis induces blood-brain barrier and neuronal damage in Huntington's disease models.
Electroacupuncture Potentiates Astragaloside IV Cerebral Delivery via P-Glycoprotein-Mediated Transcellular Transport: A Novel Blood-Brain Barrier Penetration Strategy for Ischemic Stroke Therapy.
Shouhui Tongbian capsule promotes calcium absorption by regulating gut microbiota and protects against osteoporosis.
Diacerein attenuates sepsis shock mortality through combined suppression of vascular inflammation, stiffness, and permeability.
Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress-Related Male Reproductive Dysfunction.
Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2-Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction.
Qula-derived Limosilactobacillus fermentum TD-3 and Lactococcus lactis MQ1-1 alleviate aging-related intestinal barrier dysfunction via microbiota-short-chain fatty acid-AMPK/MLCK-tight junction axis.
Nanozymes modulate probiotic tryptophan metabolism to prevent Salmonella infection in mammalian models.
Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer's Disease Agonist of PANK2.
Investigating Nickel-Induced Neurotoxicity: Associations with Gut Microbiota Dysbiosis and Ferroptosis.
Inflammation-specific DNA origami nanodevice for delivery of siRNAs to treat ulcerative colitis.
Recruiting T-cells toward the brain for enhanced glioblastoma chemo-immunotherapy efficacy by co-delivery of cytokines and temozolomide via ultrasound-gated redox-responsive extracellular vesicles.
Nicotine exacerbates MASH via inducing intestinal dysbiosis and barrier dysfunction.
Ultra-processed foods sourced 7-ketositosterol aggravates colitis through gut dysbiosis induced-PDLIM3 activation.
CRX is an intrinsic suppressor of epithelial‒mesenchymal transition in retinal pigment epithelial cells: a promising therapeutic avenue for subretinal fibrosis.
Cigarette smoke-induced lung-brain barrier dysfunction drives neurocognitive impairment via inflammatory spill-over.
Microbiota-derived indole-3-acetic acid alleviates rumen epithelial barrier dysfunction during the peripartum period through AhR signaling.
Atractylenolide III Ameliorates Ulcerative Colitis By Targeting IL-17RA to Suppress Macrophage M1 Polarization.
Multi-omics analysis identifies a microbiota-bile acid-TLR signaling axis driving bladder injury in interstitial cystitis.
Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections.
The prevalence of Yersinia enterocolitica in retail pre-prepared dishes in Xi'an and the antibacterial activity and mechanism of ε-polylysine against it.
Interindividual variability in gut microbiome mediates the efficacy of resistant starch on MASLD.
Protocol for the differentiation of induced pluripotent stem cells into retinal pigment epithelial cells.
MRI-DTI contributes to evaluating diffuse neural injury following repetitive mild traumatic brain injury.
Sunitinib Impairs Oral Mucosal Healing Through Endoplasmic Reticulum Stress-Mediated Keratinocyte Dysfunction.
Alkaline Phosphatase-Triggered Spatiotemporal Repair of Corneal Injury with TB500 Peptide Hydrogel.
Lcn2 from neutrophil extracellular traps induces astrogliosis and post-stroke emotional disorders.
Alternate-day fasting ameliorates α-synuclein pathology and suppresses inflammation via the gut-brain axis in an MPTP-induced subacute mouse model of Parkinson's disease.
Gut microbiome-derived indole-3-carboxaldehyde promotes intestinal development via AHR-NRF2 signaling in the early-life of chicks.
Clostridium scindens attenuates acute kidney injury by producing indole-3-acetic acid.
A novel long-galanin peptide from non-mammalian vertebrates mitigates the inflammatory response in IBD models via the biased GALR2/β-arrestin2 pathway.
Nano-functionalized probiotic treats atherosclerosis via inhibiting intestinal microbiota-TMA-TMAO axis.
S1PR3 Inhibition in alveolar epithelial cells alleviates pulmonary fibrosis by enhancing alveolar barrier function.
Remimazolam attenuates traumatic brain injury-induced acute lung injury by suppressing pulmonary epithelial pyroptosis.
Unique Sertoli cell adaptations support enhanced spermatogenesis in chickens.
PotD contributes to Streptococcus suis-induced blood-brain barrier disruption by regulating arcA transcription.
The DRP1 inhibitory peptide P110 provides neuroprotection after subarachnoid hemorrhage by suppressing neuronal apoptosis and stabilizing the blood-brain barrier.
Stroke-Homing Peptide-DNase1 Alleviates Intestinal Ischemia Reperfusion Injury by Selectively Degrading Neutrophil Extracellular Traps.
PD-L1 Promotes Immunological Tolerance and Enhances Visual Protection of hESC-RPE Grafts in Retinal Degeneration.
Embryonic exposure to GenX causes reproductive toxicity by disrupting the formation of the blood-testis barrier in mouse offspring.
Glyphosate Induces Anxiety-Like Behaviors in Mice via Activating NLRP3-Mediated Hippocampal Microglia Pyroptosis.
Tannic acid-iron stabilized probiotic silver nano hybrids: Multi-target gut microbiota modulation and intestinal barrier restoration.
Yeast β-glucan ameliorated Salmonella-induced gut impairment in broiler chickens by modulating gut microbiome.
Lactoferrin prevents heat stroke-induced intestinal barrier damage by reducing ferroptosis via regulating MAPK signaling pathway: In vitro and in vivo studies.
Trojan horse strategy and TfR/ LDLR-Mediated transcytosis determine the dissemination of mycobacteria in tuberculous meningoencephalitis.
Targeting CD38 to alleviate brain endothelial cell dysfunction and cognitive impairment in vascular dementia.
Improved prebiotic-based "shield" equipped probiotics for enhanced colon cancer therapy by polarizing M1 macrophages and regulating intestinal microbiota.
Kangquan formula ameliorates the benign prostatic hyperplasia induced by testosterone propionate in rats by regulating urine microecology and metabolic profile.
Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409-Ube2k-Foxp3 Axis in Regulatory T Cells.
Multiomics Reveals Nonphagocytosable Microplastics Induce Colon Inflammatory Injury via Bile Acid-Gut Microbiota Interactions and Barrier Dysfunction.
Apigenin mitigates intestinal barrier dysfunction in sepsis by modulating the AKT signaling pathway.
SPANXB1 drives brain metastasis in breast cancer via MMP1 regulation: potential therapeutic insights with metformin.
Dietary choline deficiency potentiates Helicobacter pylori-driven gut-liver dysfunction via microbial metabolic rewiring.
Anti-Obesity Effects of Pea Peptides Modified by Steam Explosion on Obese Mice: Regulation of Gut Microbiota and Glucose Metabolism.
Pediococcus acidilactici GR-5 alleviates hyperuricemia by degrading purine nucleosides and improving gut microbiota metabolism.
Hypoxia disrupts human bronchial epithelial barrier integrity via tight junction protein remodeling and enhanced paracellular leakage.
Sanren decoction ameliorates ulcerative colitis by modulating gut microbiota and macrophage polarization to enhance intestinal barrier function.
Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics.
Kynu inhibition mitigates bile duct ischemic injury by rewiring tryptophan metabolism to restore tight junction integrity.
Taurine alleviated paraquat-induced oxidative stress and gut-liver axis damage in weaned piglets by regulating the Nrf2/Keap1 and TLR4/NF-κB signaling pathways.
Oncogenic GOPC-ROS1 fusion promotes the formation of lymphatic malformations by impairing tight junction and its crizotinib resistance through repressing ferroptosis.
Flavonoid Extract of Senecio scandens Buch.-Ham. Ameliorates CTX-Induced Immunosuppression and Intestinal Damage via Activating the MyD88-Mediated Nuclear Factor-κB Signaling Pathway.
Alzheimer's Disease-Derived Outer Membrane Vesicles Exacerbate Cognitive Dysfunction, Modulate the Gut Microbiome, and Increase Neuroinflammation and Amyloid-β Production.
Long-Term High-Fat Diet Aggravates Absence Seizures and Neurobehavioral Disorders Without Inducing Metabolic Disorders in WAG/Rij Rats: Involvement of Systemic and Central Inflammation.
Inhibition of C3/C3aR Pathway Alleviates Visual and Optic Nerve Impairments in a Rat Model of Neuromyelitis Optica Spectrum Disorder.
Engineered brain-targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma.
Zinc sulfide nanoparticles serve as gas slow-release bioreactors for H(2)S therapy of ischemic stroke.
Androgen deficiency-induced loss of Lactobacillus salivarius extracellular vesicles is associated with the pathogenesis of osteoporosis.
Identification of Cell Fate Determining Transcription Factors for Generating Brain Endothelial Cells.
In vivo and In vitro assessment of the retinal toxicity of polystyrene nanoplastics.
Banxia Xiexin Decoction inhibits colitis-associated colorectal cancer development by modulating STAT3 signaling and gut microbiota.
Microbial metabolite 3-indolepropionic acid alleviated PD pathologies by decreasing enteric glia cell gliosis via suppressing IL-13Rα1 related signaling pathways.
Thalidomide mitigates Crohn's disease colitis by modulating gut microbiota, metabolites, and regulatory T cell immunity.
HMGB1 Encapsulated in Podocyte-Derived Exosomes Plays a Central Role in Glomerular Endothelial Cell Injury in Lupus Nephritis by Regulating TRIM27 Expression.
Prepubertal Exposure to Tris(2-chloroethyl) Phosphate Disrupts Blood-Testis Barrier Integrity via Ferritinophagy-Mediated Ferroptosis.
Modulation of Intestinal Barrier Function and Wnt/β- Catenin Pathway by Sanzi Formula in Colorectal Adenoma Development.
Febrile temperature-regulated TRPV1 in CD4(+) T cells mediates neuroinflammation in complex febrile seizures.
Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome.
Inhibition of CHI3L1 attenuates excessive autophagy in intestinal epithelial cells to reduce the severity of necrotizing enterocolitis.
Distinct roles of A1/A2 astrocytes in blood-brain barrier injury following cerebral I/R via the ROCK/NF-κB and STAT3 pathways.
Machine learning-based characterization of PANoptosis-related biomarkers and immune infiltration in ulcerative colitis: A comprehensive bioinformatics analysis and experimental validation.
Podophyllotoxin Alleviates DSS-Induced Ulcerative Colitis via PI3K/AKT Pathway Activation.
Cornua cervi degelatinatum inhibits breast cancer stem-like cell properties and metastasis via miR-148a-3p-mediated TGF-β/Smad2 pathway.
Colon-Targeted Mucoadhesive PLGA Microspheres Loaded with Ramulus Mori Alkaloids for Enhanced Water-Soluble Drug Delivery in Ulcerative Colitis Treatment.
FAM207A acts as a novel and potential biomarker in lung adenocarcinoma and shapes the immunesuppressive tumor microenvironment.
Card9 deficiency exacerbates vulvovaginal candidiasis by impairing the IL-17 production and vaginal epithelial barrier.
Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8(+)T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice.
PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells.
STEAP4 facilitates growth, migration, and invasion of prostate carcinoma through upregulation of NOTCH4.
HFD-induced LPS translocation and elevated blood lipids exacerbated the inflammatory response in allergic rhinitis.
Total ginsenosides from wild ginseng improve immune regulation in a rat model of spleen qi deficiency by modulating fecal-bacteria-associated short-chain fatty acids and intestinal barrier integrity.
Statin therapy associated Lactobacillus intestinalis attenuates pancreatic fibrosis through remodeling intestinal homeostasis.
Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury.
Malus hupehensis leaves: a functional beverage for alleviating hepatic inflammation and modulating gut microbiota in diabetic mice.
Lactobacillus paracasei Expressing Porcine Trefoil Factor 3 and Epidermal Growth Factor: A Novel Approach for Superior Mucosal Repair.
Proliferator-Activated Receptor Alpha Inhibits Abnormal Extracellular Matrix Accumulation and Maintains Energy Metabolism in Late-Onset Fuchs Endothelial Corneal Dystrophy.
The role of TFEB-mediated autophagy-lysosome dysfunction in manganese neurotoxicity.
Cell Membrane-Coated Nanotherapeutics for the Targeted Treatment of Acute and Chronic Colitis.
The Effect Mechanism of N6-adenosine Methylation (m6A) in Melatonin Regulated LPS-induced Colon Inflammation.
Chronic Stress-induced Serotonin Impairs Intestinal Epithelial Cell Mitochondrial Biogenesis via the AMPK-PGC-1α Axis.
Therapeutic Effects of Lifei Decoction in a Murine Model of COPD Induced by LPS and Cigarette Smoke.
Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB.
Microbiome-gut-brain axis contributes to patients and Bama miniature pigs with acute large ischemic stroke.
Trimethylamine N-oxide aggravates vascular permeability and endothelial cell dysfunction under diabetic condition: in vitro and in vivo study.
Fusobacterium Nucleatum Aggravates Intestinal Barrier Impairment and Colitis Through IL-8 Induced Neutrophil Chemotaxis by Activating Epithelial Cells.
Unleashing AdipoRon's Potential: A Fresh Approach to Tackle Pseudomonas aeruginosa Infections in Bronchiectasis via Sphingosine Metabolism Modulation.
The Predictive Value of Serum DAO, HDC, and MMP8 for the Gastrointestinal Injury in the Early Stage of Acute Pancreatitis in an Animal Model and a Clinical Study.
Lysophosphatidylcholine 14:0 Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Protecting Alveolar Epithelial Barrier by Activation of Nrf2/HO-1 Pathway.
HucMSC-Ex alleviates DSS-induced colitis in mice by decreasing mast cell activation via the IL-33/ST2 axis.
DNA methylation of miR-181a-5p mediated by DNMT3b drives renal interstitial fibrosis developed from acute kidney injury.
Cistanche deserticola polysaccharide alleviates constipation by regulating intestinal barrier function and intestinal microbiota and their metabolites.
Enriched environment may improve secondary brain injury after traumatic brain injury by regulating the TLR2/NF-κB signaling pathway.
Periplanta americana extract regulates the Th17/Treg cell balance via Notch1 in ulcerative colitis.
Huoxiang Zhengqi dropping pills alleviate exertional heat stroke-induced multiple organ injury through sustaining intestinal homeostasis via regulating MAPK/NF-κB pathway and gut microbiota in rats.
Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.
Polysaccharides derived from golden mushroom (Cantharellus cibarius Fr.) modulate gut microbiota and enhance intestinal barrier function to ameliorate dextran sulfate sodium-induced colitis in mice.
ABCA1 promote tumor environment heterogeneity via epithelial mesenchymal transition in Huh7 and HepG2 liver cancer cell.
Genome analysis of Bifidobacterium adolescentis and investigation of its effects on inflammation and intestinal barrier function.
Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosis.
Scutellarein ameliorates dextran sulfate sodium-induced ulcerative colitis by inhibiting colonic epithelial cell proinflammation and barrier disruption.
GYY4137, as a slow-releasing H(2)S donor, ameliorates sodium deoxycholate-induced chronic intestinal barrier injury and gut microbiota dysbiosis.
Hyperbaric oxygen-induced acute lung injury: A mouse model study on pathogenic characteristics and recovery dynamics.
Matrine regulates autophagy in ileal epithelial cells in a porcine circovirus type 2-infected murine model.
Gasdermin D could be lost in the brain parenchyma infarct core and a pyroptosis-autophagy inhibition effect of Jie-Du-Huo-Xue decoction after stroke.
Different effects of acute and chronic oxidative stress on the intestinal flora and gut-liver axis in weaned piglets.
Effects of the ACE2-Ang-(1-7)-Mas axis on gut flora diversity and intestinal metabolites in SuHx mice.
Circadian rhythm disruption-mediated downregulation of Bmal1 exacerbates DSS-induced colitis by impairing intestinal barrier.
Thonningianin A ameliorated renal interstitial fibrosis in diabetic nephropathy mice by modulating gut microbiota dysbiosis and repressing inflammation.
TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway.
Heat acclimation with probiotics-based ORS supplementation alleviates heat stroke-induced multiple organ dysfunction via improving intestinal thermotolerance and modulating gut microbiota in rats.
Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation.
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
Quercetin ameliorates ulcerative colitis by restoring the balance of M2/M1 and repairing the intestinal barrier via downregulating cGAS‒STING pathway.
SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Interaction of Neisseria meningitidis carrier and disease isolates of MenB cc32 and MenW cc22 with epithelial cells of the nasopharyngeal barrier.
Nocardia rubra cell-wall skeleton mitigates whole abdominal irradiation-induced intestinal injury via regulating macrophage function.
In vitro co-culture of Clostridium scindens with primary human colonic epithelium protects the epithelium against Staphylococcus aureus.
Propionate-producing engineered probiotics ameliorated murine ulcerative colitis by restoring anti-inflammatory macrophage via the GPR43/HDAC1/IL-10 axis.
Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway.
1,25-Dihydroxyvitamin D3 reduces early mortality post severe burn injury via alleviating endotoxemia, oxidative stress and inflammation.
Blueberry extract for the treatment of ischaemic stroke through regulating the gut microbiota and kynurenine metabolism.
Esculentoside H reduces the PANoptosis and protects the blood-brain barrier after cerebral ischemia/reperfusion through the TLE1/PI3K/AKT signaling pathway.
4-methylimidazole exposure impairs sperm mobility by reducing the expression of blood-testis barrier junction protein in mouse testes.
Lactobacillus gasseri ATCC33323 affects the intestinal mucosal barrier to ameliorate DSS-induced colitis through the NR1I3-mediated regulation of E-cadherin.
Carbon monoxide-releasing molecule-3 exerts neuroprotection effects after cardiac arrest in mice: A randomized controlled study.
Plant essential oils combined with organic acids restored lipopolysaccharide-induced leaky intestine via gut microbial modulation in weaned piglets.
Icariin alleviates oxygen-induced retinopathy by targeting microglia hexokinase 2.
MMP-2-mediated Scube2 degradation promotes blood-brain barrier disruption by blocking the interaction between astrocytes and endothelial cells via inhibiting Sonic hedgehog pathway during early cerebral ischemia.
Cinnamaldehyde alleviates aspirin-induced gastric mucosal injury by regulating pi3k/akt pathway-mediated apoptosis, autophagy and ferroptosis.
Microbial Tryptophan Metabolites Ameliorate Ovariectomy-Induced Bone Loss by Repairing Intestinal AhR-Mediated Gut-Bone Signaling Pathway.
Intestinal NSD2 Aggravates Nonalcoholic Steatohepatitis Through Histone Modifications.
Berberine and magnolol exert cooperative effects on ulcerative colitis in mice by self-assembling into carrier-free nanostructures.
Ternary inulin hydrogel with long-term intestinal retention for simultaneously reversing IBD and its fibrotic complication.
Esculetin Combats Multidrug-Resistant Salmonella Infection and Ameliorates Intestinal Dysfunction via the Nrf2 Pathway.
SARS-CoV-2 ORF3a Protein Impairs Syncytiotrophoblast Maturation, Alters ZO-1 Localization, and Shifts Autophagic Pathways in Trophoblast Cells and 3D Organoids.
Disulfiram attenuates cell and tissue damage and blood‒brain barrier dysfunction after intracranial haemorrhage by inhibiting the classical pyroptosis pathway.
Neohesperidin Attenuates DSS-Induced Ulcerative Colitis by Inhibiting Inflammation, Reducing Intestinal Barrier Damage, and Modulating Intestinal Flora Composition.
Allantoin ameliorates dopaminergic neuronal damage in MPTP-induced Parkinson's disease mice via regulating oxidative damage, inflammation, and gut microbiota disorder.
Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism.
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
TJP1 suppresses trophoblast cell invasion by expressing E2F8 in the human placenta.
Zinc oxide nanoparticles disrupt the mammary epithelial barrier via Z-DNA binding protein 1-triggered PANoptosis.
Oral administration of tea-derived exosome-like nanoparticles protects epithelial and immune barrier of intestine from psychological stress.
Integrating metagenomics with metabolomics for gut microbiota and metabolites profiling in acute pancreatitis.
ROS exhaustion reverses the effects of hyperbaric oxygen on hemorrhagic transformation through reactivating microglia in post-stroke hyperglycemic mice.
Protection of blood-brain barrier by endothelial DAPK1 deletion after stroke.
IL-37 protects against house dust mite-induced airway inflammation and airway epithelial barrier dysfunction via inhibiting store-operated calcium entry.
Gut microbiota dysbiosis contributes to α-synuclein-related pathology associated with C/EBPβ/AEP signaling activation in a mouse model of Parkinson's disease.
Neuroprotection of Human Umbilical Cord-Derived Mesenchymal Stem Cells (hUC-MSCs) in Alleviating Ischemic Stroke-Induced Brain Injury by Regulating Inflammation and Oxidative Stress.
Streptococcus salivarius ameliorates the destructive effect on the epithelial barrier by inhibiting the growth of Prevotella melaninogenica via metabolic acid production.
Protective properties of Ophiopogonin D in DSS-induced colitis: insights into microbiota modulation.
Linagliptin's impact on lymphatic barrier and lymphangiogenesis in oral cancer with high glucose.
Immortalized mesenchymal stromal cells overexpressing alpha-1 antitrypsin protect acinar cells from apoptotic and ferroptotic cell death.
Epicatechin and β-glucan from whole highland barley grain ameliorates hyperlipidemia associated with attenuating intestinal barrier dysfunction and modulating gut microbiota in high-fat-diet-fed mice.
Multi-omics insights into anti-colitis benefits of the synbiotic and postbiotic derived from wheat bran arabinoxylan and Limosilactobacillus reuteri.
Abelmoschi Corolla polysaccharides and related metabolite ameliorates colitis via modulating gut microbiota and regulating the FXR/STAT3 signaling pathway.
Combined effects of TiO(2) nanoparticle and fipronil co-exposure on microbiota in mouse intestine.
PPARγ/NF-κB axis contributes to cold-induced resolution of experimental colitis and preservation of intestinal barrier.
Cdk1/p53/p21 feedback loop mechanisms in the pathogenesis of interstitial cystitis/bladder pain syndrome.
Corilagin alleviates ferroptosis in diabetic retinopathy by activating the Nrf2 signaling pathway.
Galangin Alleviates Alcohol-Provoked Liver Injury Associated with Gut Microbiota Disorder and Intestinal Barrier Dysfunction in Mice.
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
ENDOTHELIAL PROX1 INDUCES BLOOD-BRAIN BARRIER DISRUPTION IN THE CENTRAL NERVOUS SYSTEM.
Kiwifruit Polysaccharides Alleviate Ulcerative Colitis via Regulating Gut Microbiota-Dependent Tryptophan Metabolism and Promoting Colon Fucosylation.
Neurons enhance blood-brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion.
Anemarrhena asphodeloides Bunge polysaccharides alleviate lipoteichoic acid-induced lung inflammation and modulate gut microbiota in mice.
Gut Lactococcus garvieae promotes protective immunity to foodborne Clostridium perfringens infection.
Human breast milk-derived phospholipid DOPE ameliorates intestinal injury associated with NEC by inhibiting ferroptosis.
Targeted Delivery of Celastrol by GA-Modified Liposomal Calcium Carbonate Nanoparticles to Enhance Antitumor Efficacy Against Breast Cancer.
DHA-enriched phosphatidylserine ameliorates cyclophosphamide-induced liver injury via regulating the gut-liver axis.
Morin alleviates DSS-induced ulcerative colitis in mice via inhibition of inflammation and modulation of intestinal microbiota.
Goat Milk Exosomes Ameliorate Ulcerative Colitis in Mice through Modulation of the Intestinal Barrier, Gut Microbiota, and Metabolites.
WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis.
eIF6 deficiency regulates gut microbiota, decreases systemic inflammation, and alleviates atherosclerosis.
Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling.
Therapeutic Potential of Foodborne Indole Derived from Chinese Stinky Tofu in Reducing Intestinal Inflammation and Enhancing Barrier Function to Mitigate Alcoholic Liver Injury.
Identification of COL3A1 as a candidate protein involved in the crosstalk between obesity and diarrhea using quantitative proteomics and machine learning.
Intermittent fasting attenuates cognitive dysfunction and systemic disease activity in mice with neuropsychiatric systemic lupus erythematosus.
Alterations in microbiota-metabolism-circRNA crosstalk in autism spectrum disorder-like behaviours caused by maternal exposure to glyphosate-based herbicides in mice.
NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice.
Cadmium Induces Vascular Endothelial Cell Detachment by Downregulating Claudin-5 and ZO-1 Levels.
Gut microbiome and metabolites mediate the benefits of caloric restriction in mice after acute kidney injury.
Reduced Proline-Rich Tyrosine Kinase 2 Promotes Tumor Metastasis by Activating Epithelial-Mesenchymal Transition in Colorectal Cancer.
Resolvin E1 and Inhibition of BLT2 Signaling Attenuate the Inflammatory Response and Improve One-Lung Ventilation-Induced Lung Injury.
PM(10) dysregulates epithelial barrier function in human corneal epithelial cells that is restored by antioxidant SKQ1.
Ferulic Acid Inhibits Arsenic-Induced Colon Injury by Improving Intestinal Barrier Function.
Exosomal miR-129-2-3p promotes airway epithelial barrier disruption in PM(2.5)-aggravated asthma.
Prevotella melaninogenica disrupted oral epithelial barrier function via myosin light chain kinase.
Mechanism of JNK action in oxidative stress-enhanced gut injury by Clostridium perfringens type A infection.
Yam protein ameliorates cyclophosphamide-induced intestinal immunosuppression by regulating gut microbiota and its metabolites.
High glucose-induced senescence contributes to tubular epithelial cell damage in diabetic nephropathy.
Oridonin alleviates cigarette smoke-induced nasal polyp formation by promoting autophagy.
Oxymatrine alleviates NSAID-associated small bowel mucosal injury by regulating MIP-1/CCR1 signalling and gut microbiota.
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
m6A-methylase METTL3 promotes retinal angiogenesis through modulation of metabolic reprogramming in RPE cells.
Multi-Omics Reveal the Improvements of Nutrient Digestion, Absorption, and Metabolism and Intestinal Function via GABA Supplementation in Weanling Piglets.
Downregulated KLF4, induced by m6A modification, aggravates intestinal barrier dysfunction in inflammatory bowel disease.
Low-Medium Polarity Ginsenosides from Wild Ginseng Improves Immunity by Activating the AhR/MAPK Pathway through Tryptophan Metabolism Driven by Gut Microbiota.
ANGPTL4 promotes choroidal neovascularization and subretinal fibrosis through the endothelial‒mesenchymal transition.
Goat milk derived small extracellular vesicles ameliorate LPS-induced intestinal epithelial barrier dysfunction, oxidative stress, and apoptosis by inhibiting the MAPK signaling pathway.
Ginsenoside Rg1 Alleviates Blood-Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive Autophagy.
Increased expression of cathepsin C in airway epithelia exacerbates airway remodeling in asthma.
The Hydrophobic Amino Acid-Rich Fish Collagen Peptide Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice via Repairing the Intestinal Barrier, Regulating Intestinal Flora and AA Metabolism.
APEX1 in intestinal epithelium triggers neutrophil infiltration and intestinal barrier damage in ulcerative colitis.
The P38MAPK Pathway Mediates the Destruction of the Blood-Brain Barrier in Anti-NMDAR Encephalitis Mice.
Naringenin Protected Against Blood Brain Barrier Breakdown after Ischemic Stroke through GSK-3β/ β-Catenin Pathway.
Bile acids supplementation improves colonic mucosal barrier via alteration of bile acids metabolism and gut microbiota composition in goats with subacute ruminal acidosis (SARA).
UCP2 knockout exacerbates sepsis-induced intestinal injury by promoting NLRP3-mediated pyroptosis.
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Inflammation-targeted delivery of Urolithin A mitigates chemical- and immune checkpoint inhibitor-induced colitis.
LSD1 deficiency in breast cancer cells promotes the formation of pre-metastatic niches.
Pomegranate Peel Extract Mitigates Diarrhea-Predominant Irritable Bowel Syndromes via MAPK and NF-κB Pathway Modulation in Rats.
Mechanism of cigarette smoke in promoting small airway remodeling in mice via STAT 3 / PINK 1-Parkin / EMT.
Epithelial Piezo1 deletion ameliorates intestinal barrier damage by regulating ferroptosis in ulcerative colitis.
Epigallocatechin gallate alleviated the in vivo toxicity of ZnO nanoparticles to mouse intestine.
Tongfu Lifei Decoction Attenuated Sepsis-Related Intestinal Mucosal Injury Through Regulating Th17/Treg Balance and Modulating Gut Microbiota.
Carnosol alleviates sepsis-induced pulmonary endothelial barrier dysfunction by targeting nuclear factor erythroid2-related factor 2/sirtuin-3 signaling pathway to attenuate oxidative damage.
Lotus Leaf Extract Alleviates Lipopolysaccharide-Induced Intestinal Injury in Mice by Regulating Oxidative Stress and Inflammation.
Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease models.
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity.
Unveiling the Novel Benefits of Co-Administering Butyrate and Active Vitamin D3 in Mice Subjected to Chemotherapy-Induced Gut-Derived Pseudomonas aeruginosa Sepsis.
RNA-sequencing expression profile and functional analysis of retinal pigment epithelium in atrophic age-related macular degeneration.
Beneficial effect of heat-killed Lactiplantibacillus plantarum L-137 on intestinal barrier function of rat small intestinal epithelial cells.
Exosomes derived from adipose tissue-derived stem cells alleviated H(2)O(2)-induced oxidative stress and endothelial-to-mesenchymal transition in human umbilical vein endothelial cells by inhibition of the mir-486-3p/Sirt6/Smad signaling pathway.
Anchang Yuyang Decoction inhibits experimental colitis-related carcinogenesis by regulating PPAR signaling pathway and affecting metabolic homeostasis of host and microbiota.
Chaihu Guizhi Ganjiang Decoction attenuates nonalcoholic steatohepatitis by enhancing intestinal barrier integrity and ameliorating PPARα mediated lipotoxicity.
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Nicotinamide Supplementation Mitigates Oxidative Injury of Bovine Intestinal Epithelial Cells through Autophagy Modulation.
FGF17 protects cerebral ischemia reperfusion-induced blood-brain barrier disruption via FGF receptor 3-mediated PI3K/AKT signaling pathway.
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
The therapeutic effects of traditional Chinese medicine on insulin resistance in obese mice by modulating intestinal functions.
Metformin attenuates lung ischemia-reperfusion injury and necroptosis through AMPK pathway in type 2 diabetic recipient rats.
Ribosomal Dysregulation in Metastatic Laryngeal Squamous Cell Carcinoma: Proteomic Insights and CX-5461's Therapeutic Promise.
An investigation into the HIF-dependent intestinal barrier protective mechanism of Qingchang Wenzhong decoction in ulcerative colitis management.
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3.
Minimally invasive vagus nerve stimulation modulates mast cell degranulation via the microbiota-gut-brain axis to ameliorate blood-brain barrier and intestinal barrier damage following ischemic stroke.
Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice.
Ginsenoside CK Alleviates DSS-Induced IBD in Mice by Regulating Tryptophan Metabolism and Activating Aryl Hydrocarbon Receptor via Gut Microbiota Modulation.
Cuproptosis mediates copper-induced testicular spermatogenic cell death.
Narirutin Attenuates Cerebral Ischemia-Reperfusion Injury by Suppressing the TXNIP/NLRP3 Pathway.
Inhibition of EphA4 reduces vasogenic edema after experimental stroke in mice by protecting the blood-brain barrier integrity.
Age-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.
Cornuside protects against ischemic stroke in rats by suppressing the IL-17F/TRAF6/NF-κB pathway via the brain-gut axis.
Engineered mesenchymal stem cell-derived small extracellular vesicles for diabetic retinopathy therapy through HIF-1α/EZH2/PGC-1α pathway.
Selective HDAC6 inhibition protects against blood-brain barrier dysfunction after intracerebral hemorrhage.
Amelioration of obesity and inflammation by polysaccharide from unripe fruits of raspberry via gut microbiota regulation.
Ageratina adenophora causes intestinal integrity damage in goats via the activation of the MLCK/ROCK signaling pathway.
Golden bifid treatment regulates gut microbiota and serum metabolites to improve myocardial dysfunction in cecal ligation and puncture-induced sepsis mice.
Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora.
Zinc lactate alleviates oxidative stress by modulating crosstalk between constitutive androstane receptor signaling pathway and gut microbiota profile in weaned piglets.
AhR Activation Ameliorates Intestinal Barrier Damage in Immunostressed Piglets by Regulating Intestinal Flora and Its Metabolism.
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Environmentally realistic dose of tire-derived metabolite 6PPD-Q exposure causes intestinal jejunum and ileum damage in mice via cannabinoid receptor-activated inflammation.
RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells.
Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model.
Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline-Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora.
Selenomethionine Alleviates Deoxynivalenol-Induced Oxidative Injury in Porcine Intestinal Epithelial Cells Independent of MAPK Pathway Regulation.
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
Trifluoperazine regulates blood-brain barrier permeability via the MLCK/p-MLC pathway to promote ischemic stroke recovery.
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice.
Achyranthes bidentata polysaccharide ameliorates type 2 diabetes mellitus by gut microbiota-derived short-chain fatty acids-induced activation of the GLP-1/GLP-1R/cAMP/PKA/CREB/INS pathway.
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner.
Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 pathway.
Rosa laevigata Polysaccharides Ameliorate Dextran Sulfate Sodium-Induced Ulcerative Colitis of Beagles through Regulating Gut Microbiota.
Network analysis of microbiome and metabolome to explore the mechanism of raw rhubarb in the protection against ischemic stroke via microbiota-gut-brain axis.
Effects of electrolyte balance on intestinal barrier, amino acid metabolism, and mTORC1 signaling pathway in piglets fed low-protein diets.
Paeoniflorin ameliorates chronic colitis via the DR3 signaling pathway in group 3 innate lymphoid cells.
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Prevotella copri transplantation promotes neurorehabilitation in a mouse model of traumatic brain injury.
Tedizolid phosphate alleviates DSS-induced ulcerative colitis by inhibiting senescence of cell and colon tissue through activating AMPK signaling pathway.
Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways.
Network pharmacology and experimental validation to explore the mechanism of Changji'an formula against irritable bowel syndrome with predominant diarrhea.
Effect and mechanism of Prunella vulgaris L. extract on alleviating lipopolysaccharide-induced acute mastitis in protecting the blood-milk barrier and reducing inflammation.
Neferine inhibits BMECs pyroptosis and maintains blood-brain barrier integrity in ischemic stroke by triggering a cascade reaction of PGC-1α.
MyD88 Inhibition Attenuates Cerebral Ischemia-reperfusion Injury by Regulating the Inflammatory Response and Reducing Blood-brain Barrier Damage.
3D model of mouse embryonic pancreas and endocrine compartment using stem cell-derived mesoderm and pancreatic progenitors.
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Fucoxanthin alleviates lipopolysaccharide-induced intestinal barrier injury in mice.
Heyingwuzi formulation alleviates diabetic retinopathy by promoting mitophagy via the HIF-1α/BNIP3/NIX axis.
Elucidating the modulatory role of dietary hydroxyproline on the integrity and functional performance of the intestinal barrier in early-weaned piglets: A comprehensive analysis of its interplay with the gut microbiota and metabolites.
ACE2 mediates tryptophan alleviation on diarrhea by repairing intestine barrier involved mTOR pathway.
Butyrate attenuates sympathetic activation in rats with chronic heart failure by inhibiting microglial inflammation in the paraventricular nucleus.
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy.
Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier.
Anthrahydroquinone‑2,6‑disulfonate attenuates PQ‑induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of the PI3K/AKT/eNOS pathway.
Mucoadhesive chitosan-catechol as an efficient vaccine delivery system for intranasal immunization.
Development of an Inflamed High Throughput Stem-cell-based Gut Epithelium Model to Assess the Impact of Annexin A1.
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Dietary emulsifier polysorbate 80 exposure accelerates age-related cognitive decline.
Inhibition of Experimental Corneal Neovascularization by the Tight Junction Protein ZO-1.
Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression.
Dietary Protease Supplementation Improved Growth Performance and Nutrients Digestion via Modulating Intestine Barrier, Immunological Response, and Microbiota Composition in Weaned Piglets.
New advances of NG2-expressing cell subset in marrow mesenchymal stem cells as novel therapeutic tools for liver fibrosis/cirrhosis.
Sestrin2 Restricts Endothelial-to-Mesenchymal Transition Induced by Lipolysaccharide via Autophagy.
The Use of Polysaccharide AOP30 from the Rhizome of Alpinia officinarum Hance to Alleviate Lipopolysaccharide-Induced Intestinal Epithelial Barrier Dysfunction and Inflammation via the TLR4/NfκB Signaling Pathway in Caco-2 Cell Monolayers.
Platelet-rich plasma-derived exosomes promote blood-spinal cord barrier repair and attenuate neuroinflammation after spinal cord injury.
The Barrier Disruption and Pyroptosis of Intestinal Epithelial Cells Caused by Perfringolysin O (PFO) from Clostridium perfringens.
Study on the mechanism of mitigating radiation damage by improving the hematopoietic system and intestinal barrier with Tenebrio molitor peptides.
Protection of Tight Junctional Complexes between hCMEC/D3 Cells by Deep-Sea Fibrinolytic Compound FGFC1.
Arbutin alleviates intestinal colitis by regulating neutrophil extracellular traps formation and microbiota composition.
Narirutin mitigates dextrose sodium sulfate-induced colitis in mice by modulating intestinal flora.
High correlated color temperature artificial lighting impairs retinal pigment epithelium integrity and chloride ion transport: A potential mechanism for choroidal thinning.
Protective effects of patchouli alcohol against DSS-induced ulcerative colitis.
Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells.
Neuroprotection of macamide in a mouse model of Alzheimer's disease involves Nrf2 signaling pathway and gut microbiota.
Nerve growth factor alleviates arsenic-induced testicular injury by enhancing the function of Sertoli cells.
Epigallocatechin-3-gallate mitigates cadmium-induced intestinal damage through modulation of the microbiota-tryptophan-aryl hydrocarbon receptor pathway.
Apple polysaccharide improves age-matched cognitive impairment and intestinal aging through microbiota-gut-brain axis.
Maternal exposure to DON during lactation induces testicular toxicity in pubertal and adult offspring mice.
pH Sensitive Quercetin Nanoparticles Ameliorate DSS-Induced Colitis in Mice by Colon-Specific Delivery.
Addition of α-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems.
Quercetin ameliorates ulcerative colitis by activating aryl hydrocarbon receptor to improve intestinal barrier integrity.
Simultaneous ischemic regions targeting and BBB crossing strategy to harness extracellular vesicles for therapeutic delivery in ischemic stroke.
Angiotensin-converting enzyme inhibitory peptide IVGFPAYGH protects against liver injury in mice fed a high‑sodium diet by inhibiting the RAS and remodeling gut microbial communities.
Chitosan-coated artesunate protects against ulcerative colitis via STAT6-mediated macrophage M2 polarization and intestinal barrier protection.
PSD-95 inhibitor Tat-NR2B9c (NA-1) protects the integrity of the blood-brain barrier after transient middle artery occlusion in rats by downregulating matrix metalloprotease-9 and upregulating endothelial nitric oxide synthase.
An Erythrocyte Membrane-Derived Nanosystem for Efficient Reversal of Endothelial Injury in Sepsis.
The protective effects of icariin against testicular dysfunction in type 1 diabetic mice Via AMPK-mediated Nrf2 activation and NF-κB p65 inhibition.
Cantharidin-induced toxic injury, oxidative stress, and autophagy attenuated by Astragalus polysaccharides in mouse testis.
Probiotic Clostridium butyricum ameliorates cognitive impairment in obesity via the microbiota-gut-brain axis.
Trimethylamine-N oxide enhances post-stroke depression progression via ROS-p38/MAPK signaling.
Infant feces-derived Lactobacillus gasseri FWJL-4 mitigates experimental necrotizing enterocolitis via acetate production.
Gut microbiota promotes macrophage M1 polarization in hepatic sinusoidal obstruction syndrome via regulating intestinal barrier function mediated by butyrate.
Prevotella copri promotes vascular calcification via lipopolysaccharide through activation of NF-κB signaling pathway.
Meta-analysis identifying gut microbial biomarkers of Qinghai-Tibet Plateau populations and the functionality of microbiota-derived butyrate in high-altitude adaptation.
Renal macrophages monitor and remove particles from urine to prevent tubule obstruction.
Study on the Anti-Ulcerative Colitis Effect of Pseudo-Ginsenoside RT4 Based on Gut Microbiota, Pharmacokinetics, and Tissue Distribution.
Macrophage-derived MMP12 promotes fibrosis through sustained damage to endothelial cells.
Inhibition of circulating exosomes release with GW4869 mitigates severe acute pancreatitis-stimulated intestinal barrier damage through suppressing NLRP3 inflammasome-mediated pyroptosis.
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
FTO-mediated m6A modification of serum amyloid A2 mRNA promotes podocyte injury and inflammation by activating the NF-κB signaling pathway.
The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway.
Standalone cell culture microfluidic device-based microphysiological system for automated cell observation and application in nephrotoxicity tests.
Targeted mRNA Nanoparticles Ameliorate Blood-Brain Barrier Disruption Postischemic Stroke by Modulating Microglia Polarization.
Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.
Ageratina adenophora damages the rumen epithelium via inducing the expression of inflammatory factors in goats.
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium.
Dietary supplementation of benzoic acid and essential oils combination enhances intestinal resilience against LPS stimulation in weaned piglets.
A Platform for Testing the Biocompatibility of Implants: Silicone Induces a Proinflammatory Response in a 3D Skin Equivalent.
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.
Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis.
Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox.
Levofloxacin alleviates blood-brain barrier disruption following cerebral ischemia and reperfusion via directly inhibiting A-FABP.
Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway.
Baitouweng decoction repairs the intestinal barrier in DSS-induced colitis mice via regulation of AMPK/mTOR-mediated autophagy.
Torreya grandis Kernel Oil Alleviates Loperamide-Induced Slow Transit Constipation via Up-Regulating the Colonic Expressions of Occludin/Claudin-1/ZO-1 and 5-HT3R/5-HT4R in BALB/c Mice.
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Gut microbiota dysbiosis and intestinal barrier impairment in diarrhea caused by cold drink and high-fat diet.
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Assessment of osteopontin as an early nephrotoxicity indicator in human renal proximal tubule cells and its application in evaluating lanthanum-induced nephrotoxicity.
Bone morphogenetic protein 4 thermosensitive hydrogel inhibits corneal neovascularization by repairing corneal epithelial apical junctional complexes.
peu-MIR2916-p3-enriched garlic exosomes ameliorate murine colitis by reshaping gut microbiota, especially by boosting the anti-colitic Bacteroides thetaiotaomicron.
Fluorene-9-bisphenol exposure damages the testis in mice through a novel mechanism of ferroptosis.
Fermentation enhances the amelioration effect of bee pollen on Caco-2 monolayer epithelial barrier dysfunction based on NF-κB-mediated MLCK-MLC signaling pathway.
Sinomenine regulates the cholinergic anti-inflammatory pathway to inhibit TLR4/NF-κB pathway and protect the homeostasis in brain and gut in scopolamine-induced Alzheimer's disease mice.
Electroacupuncture at ST36 modulates the intestinal microecology and may help repair the intestinal barrier in the rat model of severe acute pancreatitis.
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
(-)-Syringaresinol attenuates ulcerative colitis by improving intestinal epithelial barrier function and inhibiting inflammatory responses.
CpxAR two-component system contributes to virulence properties of Cronobacter sakazakii.
Microsporidia persistence in host impairs epithelial barriers and increases chances of inflammatory bowel disease.
The Effects of Yeast Protein on Gut Microbiota in Mice When Compared with Soybean Protein and Whey Protein Isolates.
Neuron Derived Cold-Inducible RNA-Binding Protein Promotes NETs Formation to Exacerbate Brain Endothelial Barrier Disruption after Ischemic Stroke.
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice.
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.
Cathepsin B-Responsive Programmed Brain Targeted Delivery System for Chemo-Immunotherapy Combination Therapy of Glioblastoma.
An Inulin-Type Fructan CP-A from Codonopsis pilosula Alleviated 5-Fluorouracil-Induced Intestinal Mucositis via the ERK/MLCK/MLC2 Pathway and Regulation of Gut Microbiota.
Intrauterine Growth Restriction Affects Colonic Barrier Function via Regulating the Nrf2/Keap1 and TLR4-NF-κB/ERK Pathways and Altering Colonic Microbiome and Metabolome Homeostasis in Growing-Finishing Pigs.
The microbial metabolite urolithin A reduces Clostridioides difficile toxin expression and toxin-induced epithelial damage.
A Mixture of Formic Acid, Benzoic Acid, and Essential Oils Enhanced Growth Performance via Modulating Nutrient Uptake, Mitochondrion Metabolism, and Immunomodulation in Weaned Piglets.
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
A single cell atlas of circulating immune cells involved in diabetic retinopathy.
Disrupting the gut microbiota/metabolites axis by Di-(2-ethylhexyl) phthalate drives intestinal inflammation via AhR/NF-κB pathway in mice.
Isofraxidin attenuates dextran sulfate sodium-induced ulcerative colitis through inhibiting pyroptosis by upregulating Nrf2 and reducing reactive oxidative species.
Melatonin alleviates necrotizing enterocolitis by reducing bile acid levels through the SIRT1/FXR signalling axis.
Irisin links Claudin-5 preservation and Mfn2-mediated mitochondrial dynamics to resist doxorubicin-induced cardiac endothelial damage.
Icariin Regulates EMT and Stem Cell-Like Character in Breast Cancer through Modulating lncRNA NEAT1/TGFβ/SMAD2 Signaling Pathway.
DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.
A multi-omics analysis of viral nucleic acid poly(I:C) responses to mammalian testicular stimulation.
Inulin alleviates perfluorooctanoic acid-induced intestinal injury in mice by modulating the PI3K/AKT/mTOR signaling pathway.
Therapeutic potential of Lacticaseibacillus rhamnosus grx10 and its derived postbiotic through gut microbiota and MAPK/MLCK/MLC pathway-mediated intestinal barrier repairment in ulcerative colitis.
SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.
An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain.
Effects of Intestinal M Cells on Intestinal Barrier and Neuropathological Properties in an AD Mouse Model.
Nicotinamide mononucleotide protects STAT1 from oxidative stress-induced degradation to prevent colorectal tumorigenesis.
Tea-derived exosome-like nanoparticles prevent irritable bowel syndrome induced by water avoidance stress in rat model.
Targeted reprogramming of tumor-associated macrophages for overcoming glioblastoma resistance to chemotherapy and immunotherapy.
Methane saline suppresses ferroptosis via the Nrf2/HO-1 signaling pathway to ameliorate intestinal ischemia-reperfusion injury.
Rehmannia glutinosa polysaccharides enhance intestinal immunity of mice through regulating the microbiota.
Schisandra chinensis polysaccharide prevents alcohol-associated liver disease in mice by modulating the gut microbiota-tryptophan metabolism-AHR pathway axis.
RVG-peptide-camouflaged iron-coordinated engineered polydopamine nanoenzyme with ROS scavenging and inhibiting inflammatory response for ischemic stroke therapy.
Tanshinone IIA Exerts Cardioprotective Effects Through Improving Gut-Brain Axis Post-Myocardial Infarction.
Growth hormone attenuates obesity and reshapes gut microbiota in high-fat diet-fed mice.
SOX9 regulates epithelial-mesenchymal transformation by mediating the Wnt/β-catenin signaling pathway in hypospadias.
Lactobacillus reuteri or Lactobacillus rhamnosus GG intervention facilitates gut barrier function, decreases corticosterone and ameliorates social behavior in LPS-exposed offspring.
Intestinal barrier, immunity and gut microbiota-based protective effects of Lactococcus lactis HF08 and its postbiotic derivative on aging and aging colitis mice.
Dietary sanguinarine supplementation improves the growth performance and intestinal immunity of broilers.
Hymenolepis nana antigens alleviate ulcerative colitis by promoting intestinal stem cell proliferation and differentiation via AhR/IL-22 signaling pathway.
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Counteracting Alzheimer's disease via normalizing neurovascular unit with a self-regulated multi-functional nano-modulator.
Licorice-regulated gut-joint axis for alleviating collagen-induced rheumatoid arthritis.
Ganjiang Huangqin Huanglian Renshen Decoction protects against ulcerative colitis by modulating inflammation, oxidative stress, and gut microbiota.
Chidan Tuihuang granule modulates gut microbiota to influence NOD1/RIPK2 pathway in cholestatic liver injury recovery.
Jianwei Shoutai Pills alleviates miscarriage by modulating gut microbial production of BAs and NLRP3-inflammasome at the maternal-fetal interface of rats.
Xuanfei Baidu decoction ameliorates bleomycin-elicited idiopathic pulmonary fibrosis in mice by regulating the lung-gut crosstalk via IFNγ/STAT1/STAT3 axis.
Resistant starch confers protection of dietary against diabetic cardiomyopathy.
Lipopolysaccharide-regulated RNF31/NRF2 axis in colonic epithelial cells mediates homeostasis of the intestinal barrier in ulcerative colitis.
Identification of Ferroptosis-Related Gene in Age-Related Macular Degeneration Using Machine Learning.
ReBiA-Robotic Enabled Biological Automation: 3D Epithelial Tissue Production.
Quercetin prevents the USP22-Snail1 signaling pathway to ameliorate diabetic tubulointerstitial fibrosis.
Xiaoyaosan against depression through suppressing LPS mediated TLR4/NLRP3 signaling pathway in "microbiota-gut-brain" axis.
Isoastragaloside I attenuates cholestatic liver diseases by ameliorating liver injury, regulating bile acid metabolism and restoring intestinal barrier.
Therapeutic Efficacy and Underlying Mechanisms of a Mannoglucan from Hirsutella sinensis Mycelium on Dextran Sulfate Sodium-Induced Inflammatory Bowel Disease in Mice: Modulation of the Intestinal Barrier, Oxidative Stress and Gut Microbiota.
High-fat diet led to testicular inflammation and ferroptosis via dysbiosis of gut microbes.
Formononetin ameliorates dextran sulfate sodium-induced colitis via enhancing antioxidant capacity, promoting tight junction protein expression and reshaping M1/M2 macrophage polarization balance.
Efficacy of DHA-enriched phosphatidylserine and its underlying mechanism in alleviating polystyrene nanoplastics-induced hepatotoxicity in mice.
FGF20 modulates gut microbiota to mitigate dextran sodium sulfate-induced ulcerative colitis in mouse models.
Salidroside alleviates ferroptosis in FAC-induced Age-related macular degeneration models by activating Nrf2/SLC7A11/GPX4 axis.
Bone morphogenetic protein 4 inhibits corneal neovascularization by blocking NETs-induced disruption to corneal epithelial barrier.
Intranasal administration of Clostridium butyricum and its derived extracellular vesicles alleviate LPS-induced acute lung injury.
The host cells suppress the proliferation of pseudorabies virus by regulating the PI3K/Akt/mTOR pathway.
Rewiring Tryptophan Metabolism via Programmable Probiotic Integrated by Dual-Layered Microcapsule Protects against Inflammatory Bowel Disease in Mice.
CD8+T cell infiltration-associated barrier function of brain endothelial cells is enhanced by astragalus polysaccharides via inhibiting the PI3K/AKT signaling pathway.
Gut-Microbiota-Derived Butyric Acid Overload Contributes to Ileal Mucosal Barrier Damage in Late Phase of Chronic Unpredictable Mild Stress Mice.
Spint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA.
N7-methyladenosine-induced SLC7A7 serves as a prognostic biomarker in pan-cancer and promotes CRC progression in colorectal cancer.
Snake venom weakens neurovascular integrity and promotes vulnerability to neuroinflammation.
Nicotinamide adenine dinucleotide phosphate alleviates intestinal ischemia/reperfusion injury via Nrf2/HO-1 pathway.
Neutrophil extracellular traps induce barrier dysfunction in DSS-induced ulcerative colitis via the cGAS-STING pathway.
Sphk1/S1P pathway promotes blood-brain barrier breakdown after intracerebral hemorrhage through inducing Nlrp3-mediated endothelial cell pyroptosis.
Salivary adenoid cystic carcinoma-derived α2,6-sialylated extracellular vesicles increase vascular permeability by triggering ER-stress in endothelial cells and promote lung metastasis.
Role of Rab13, Protein Kinase A, and Zonula Occludens-1 in Hepatitis E Virus Entry and Cell-to-Cell Spread: Comparative Analysis of Quasi-Enveloped and Non-Enveloped Forms.
Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability.
Fructo-oligosaccharides Alleviated Ulcerative Colitis via Gut Microbiota-Dependent Tryptophan Metabolism in Association with Aromatic Hydrocarbon Receptor Activation in Mice.
Inhibition of AhR disrupts intestinal epithelial barrier and induces intestinal injury by activating NF-κB in COPD.
2-(3,4-Dihydroxyphenyl)ethyl 3-hydroxybutanoate Ameliorates Cognitive Dysfunction and Inflammation Via Modulating Gut Microbiota in Aged Senescence-Accelerated Mouse Prone8 Mice.
Inulin alleviates GenX-induced intestinal injury in mice by modulating the MAPK pathway, cell cycle, and cell adhesion proteins.
Omega-3 Polyunsaturated Fatty Acids Alleviate Intestinal Barrier Dysfunction in Obstructive Jaundice Rats.
Raddeanin A Protects the BRB Through Inhibiting Inflammation and Apoptosis in the Retina of Alzheimer's Disease.
HSP70 protects against acute pancreatitis-elicited intestinal barrier damage in rats.
Fecal Microbiota Transplantation Alleviates Allergic Rhinitis via CD4(+) T Cell Modulation Through Gut Microbiota Restoration.
Auraptene Mitigates Colitis Induced by Dextran Sulfate Sodium in Mice by Regulating Specific Intestinal Flora and Repairing the Intestinal Barrier.
Long noncoding RNA H19 knockdown promotes angiogenesis via IMP2 after ischemic stroke.
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
A2 reactive astrocyte-derived exosomes alleviate cerebral ischemia-reperfusion injury by delivering miR-628.
Chitosan-alginate/R8 ternary polyelectrolyte complex as an oral protein-based vaccine candidate induce effective mucosal immune responses.
Nur77 as a novel regulator of Paneth cell differentiation and function.
Dissection of triple-negative breast cancer microenvironment and identification of potential therapeutic drugs using single-cell RNA sequencing analysis.
Expression of MAF bZIP transcription factor B protects against ulcerative colitis through the inhibition of the NF-κB pathway.
A Glucose-Responsive Hydrogel Inhibits Primary and Secondary BRB Injury for Retinal Microenvironment Remodeling in Diabetic Retinopathy.
Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.
Schisandrin B alleviates testicular inflammation and Sertoli cell apoptosis via AR-JNK pathway.
Gut-derived memory γδ T17 cells exacerbate sepsis-induced acute lung injury in mice.
Colonization of microbiota derived from Macaca fascicularis, Bama miniature pigs, beagle dogs, and C57BL/6J mice alleviates DSS-induced colitis in germ-free mice.
The Novel-m0230-3p miRNA Modulates the CSF1/CSF1R/Ras Pathway to Regulate the Cell Tight Junctions and Blood-Testis Barrier in Yak.
Ultrasound-responsive theranostic platform for the timely monitoring and efficient thrombolysis in thrombi of tPA resistance.
Pasteurella multocida infection induces blood-brain barrier disruption by decreasing tight junctions and adherens junctions between neighbored brain microvascular endothelial cells.
Pseudorabies virus infection increases the permeability of the mammalian respiratory barrier to facilitate Pasteurella multocida infection.
Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy.
Integrated Multi-Omics Analysis Reveals Mountain-Cultivated Ginseng Ameliorates Cold-Stimulated Steroid-Resistant Asthma by Regulating Interactions among Microbiota, Genes, and Metabolites.
Role of gut microbiota in Crohn's disease pathogenesis: Insights from fecal microbiota transplantation in mouse model.
Epimedii Folium decoction ameliorates osteoporosis in mice through NLRP3/caspase-1/IL-1β signalling pathway and gut-bone axis.
GM130-silencing may aggravate blood-brain barrier damage and affect microglia polarization by down-regulating PD-L1 expression after experimental intracerebral hemorrhage.
Oral alginate microspheres for the efficient site-specific delivery of epidermal growth factor attenuated murine ulcerative colitis via repairing the mucosal barrier.
Seliciclib alleviates ulcerative colitis by inhibiting ferroptosis and improving intestinal inflammation.
Dietary rutin improves the antidiarrheal capacity of weaned piglets by improving intestinal barrier function, antioxidant capacity and cecal microbiota composition.
Kidney-tonifying blood-activating decoction delays ventricular remodeling in rats with chronic heart failure by regulating gut microbiota and metabolites and p38 mitogen-activated protein kinase/p65 nuclear factor kappa-B/aquaporin-4 signaling pathway.
Pueraria lobata-Prunus mume Complex Alleviates Alcoholic Liver Disease by Regulating Lipid Metabolism and Inhibiting Inflammation: A Transcriptome and Gut Microbiota Analysis.
l-Theanine Prevents Colonic Damage via NF-κB/MAPK Signaling Pathways Induced by a High-Fat Diet in Rats.
Naringenin Alleviates Radiation-Induced Intestinal Injury by Inhibiting TRPV6 in Mice.
Protective Mechanism of Polysaccharide ORP-1 Isolated from Oudemansiella raphanipes against Age-Related Cognitive Decline through the Microbiota-Gut-Brain Axis.
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Protective effect of cilostazol on vascular injury in rats with acute ischemic stroke complicated with chronic renal failure.
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology.
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
L-theanine attenuates H(2)O(2)-induced inflammation and apoptosis in IPEC-J2 cells via inhibiting p38 MAPK signaling pathway.
Trilobatin attenuates cerebral ischaemia/reperfusion-induced blood-brain barrier dysfunction by targeting matrix metalloproteinase 9: The legend of a food additive.
A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease.
Alleviation of allergic asthma by rosmarinic acid via gut-lung axis.
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
Occludin and collagen IV degradation mediated by the T9SS effector SspA contributes to blood-brain barrier damage in ducks during Riemerella anatipestifer infection.
Faecalibacterium prausnitzii Supplementation Prevents Intestinal Barrier Injury and Gut Microflora Dysbiosis Induced by Sleep Deprivation.
Exploring the mechanism of Bushen Huoxue prescription in the treatment of early diabetic retinal edema from the perspective of inner blood-retinal barrier injury.
Canagliflozin protects against hyperglycemia-induced cerebrovascular injury by preventing blood-brain barrier (BBB) disruption via AMPK/Sp1/adenosine A2A receptor.
The Lactobacillus plantarum P-8 Probiotic Microcapsule Prevents DSS-Induced Colitis through Improving Intestinal Integrity and Reducing Colonic Inflammation in Mice.
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Bone-derived PDGF-BB enhances hippocampal non-specific transcytosis through microglia-endothelial crosstalk in HFD-induced metabolic syndrome.
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines.
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
miR-186-5p improves alveolar epithelial barrier function by targeting the wnt5a/β-catenin signaling pathway in sepsis-acute lung injury.
Acupuncture Extended the Thrombolysis Window by Suppressing Blood-Brain Barrier Disruption and Regulating Autophagy-Apoptosis Balance after Ischemic Stroke.
Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway.
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Long-Term Triclocarban Exposure Induced Enterotoxicity by Triggering Intestinal AhR-Mediated Inflammation and Disrupting Microbial Community in Mice.
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Microneedle array facilitates hepatic sinusoid construction in a large-scale liver-acinus-chip microsystem.
Caulerpa lentillifera improves ethanol-induced liver injury and modulates the gut microbiota in rats.
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
Panax notoginseng Alleviates Colitis via the Regulation of Gut Microbiota.
Functional Peptide-Modified Liposomes for siRNA Delivery to Rat Retinal Pigment Epithelium Cells: Effect of Peptide Sequences.
Butylphthalide improves brain damage induced by renal ischemia-reperfusion injury rats through Nrf2/HO-1 and NOD2/MAPK/NF-κB pathways.
A microfluidic thyroid-liver platform to assess chemical safety in humans.
Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle.
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Upregulated SSB Is Involved in Hepatocellular Carcinoma Progression and Metastasis through the Epithelial-Mesenchymal Transition, Antiapoptosis, and Altered ROS Level Pathway.
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
A hydrogel model of the human blood-brain barrier using differentiated stem cells.
Shensong Yangxin Capsule Reduces the Susceptibility of Arrhythmia in db/db Mice via Inhibiting the Inflammatory Response Induced by Endothelium Dysfunction.
Indole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Experimental Colitis Models.
Suppression of Wnt/β-catenin Signaling in PDAC via METTL16-mediated N6-methyladenosine Modification of DVL2.
Bacteroides acidifaciens and its derived extracellular vesicles improve DSS-induced colitis.
The immunity protection of intestine induced by pseudorabies virus del gI/gE/TK in piglets.
Leveraging a gene signature associated with disulfidptosis identified by machine learning to forecast clinical outcomes, immunological heterogeneities, and potential therapeutic targets within lower-grade glioma.
Fecal microbiota transplantation from HUC-MSC-treated mice alleviates acute lung injury in mice through anti-inflammation and gut microbiota modulation.
β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis.
Ultrasound-assisted intravesical botulinum toxin A delivery attenuates acetic acid-induced bladder hyperactivity in rats.
Mahuang Fuzi Xixin decoction ameliorates allergic rhinitis and repairs the airway epithelial barrier by modulating the lung microbiota dysbiosis.
Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness.
Intermittent fasting protects against food allergy in a murine model via regulating gut microbiota.
Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.
Circulating sepsis-related metabolite sphinganine could protect against intestinal damage during sepsis.
Whole intestinal microbiota transplantation is more effective than fecal microbiota transplantation in reducing the susceptibility of DSS-induced germ-free mice colitis.
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Zengshengping improves lung cancer by regulating the intestinal barrier and intestinal microbiota.
Establishment of a porcine bronchial epithelial cell line and its application to study innate immunity in the respiratory epithelium.
Network pharmacology and experimental study of phenolic acids in salvia miltiorrhiza bung in preventing ischemic stroke.
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury.
Jinhong decoction protects sepsis-associated acute lung injury by reducing intestinal bacterial translocation and improving gut microbial homeostasis.
Wnt4 increases the thickness of the epidermis in burn wounds by activating canonical Wnt signalling and decreasing the cell junctions between epidermal cells.
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Efficient Therapy of Inflammatory Bowel Disease (IBD) with Highly Specific and Durable Targeted Ta(2) C Modified with Chondroitin Sulfate (TACS).
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury.
Lactiplantibacillus plantarum L47 and inulin alleviate enterotoxigenic Escherichia coli induced ileal inflammation in piglets by upregulating the levels of α-linolenic acid and 12,13-epoxyoctadecenoic acid.
Dietary emodin alleviates lipopolysaccharide-induced intestinal mucosal barrier injury by regulating gut microbiota in piglets.
Maslinic acid alleviates LPS-induced mice mastitis by inhibiting inflammatory response, maintaining the integrity of the blood-milk barrier and regulating intestinal flora.
Maintenance of airway epithelial barrier integrity via the inhibition of AHR/EGFR activation ameliorates chronic obstructive pulmonary disease using effective-component combination.
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
The panda-derived Lactiplantibacillus plantarum BSG201683 improves LPS-induced intestinal inflammation and epithelial barrier disruption in vitro.
A novel small molecule effectively ameliorates estrogen deficiency-induced osteoporosis by targeting the gut-bone signaling axis.
Gut microbiota modulate distal symmetric polyneuropathy in patients with diabetes.
The mechanism of simultaneous intake of Jujuboside A and B in the regulation of sleep at the hypothalamic level.
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Sea Conch Peptides Hydrolysate Alleviates DSS-Induced Colitis in Mice through Immune Modulation and Gut Microbiota Restoration.
Long-term PM2.5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models.
Multiomics reveal human umbilical cord mesenchymal stem cells improving acute lung injury via the lung-gut axis.
Fasting-mimicking diet alleviates inflammatory pain by inhibiting neutrophil extracellular traps formation and neuroinflammation in the spinal cord.
Pterostilbene alleviated cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction via inhibiting early endothelial cytoskeleton reorganization and late basement membrane degradation.
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Effects of DON on Mitochondrial Function, Endoplasmic Reticulum Stress, and Endoplasmic Reticulum Mitochondria Contact Sites in the Jejunum of Piglets.
Catalysis-Mediated Male Contraception through Black Phosphorus Nanosheets.
Cerebrospinal Fluid Pressure Reduction Induces Glia-Mediated Retinal Inflammation and Leads to Retinal Ganglion Cell Injury in Rats.
The therapeutic value of adipose-derived pericyte transplantation after intracerebral hemorrhage in rats.
Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans.
Oncogenic BRAF noncanonically promotes tumor metastasis by mediating VASP phosphorylation and filopodia formation.
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Repeated Social Defeat Stress Induces an Inflammatory Gut Milieu by Altering the Mucosal Barrier Integrity and Gut Microbiota Homeostasis.
Lactiplantibacillus plantarum Strain FLPL05 Promotes Longevity in Mice by Improving Intestinal Barrier.
3D Bioprinting of Neurovascular Tissue Modeling with Collagen-Based Low-Viscosity Composites.
Chlorogenic Acid Ameliorates Post-Infectious Irritable Bowel Syndrome by Regulating Extracellular Vesicles of Gut Microbes.
Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease.
Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism.
Dietary Betaine Supplementation Enhances Colonic Barrier Function through the Nrf2/Keap1 and TLR4-NF-κB/MAPK Signaling Pathways and Alters Colonic Microbiota in Bama Mini-Pigs.
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Atractylodes lancea Rhizome Polysaccharide Alleviates Immunosuppression and Intestinal Mucosal Injury in Mice Treated with Cyclophosphamide.
FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.
Effect of Cordyceps militaris Powder Prophylactic Supplementation on Intestinal Mucosal Barrier Impairment and Microbiota-Metabolites Axis in DSS-Injured Mice.
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis.
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Effects of Enteromorpha prolifera polysaccharides on growth performance, intestinal barrier function and cecal microbiota in yellow-feathered broilers under heat stress.
miR-379-5P INHIBITION ENHANCES INTESTINAL EPITHELIAL PROLIFERATION AND BARRIER FUNCTION RECOVERY AFTER ISCHEMIA/REPERFUSION BY TARGETING EIF4G2.
Role of SIRT2 in intestinal barrier under cold exposure.
The coexistence of aflatoxin M1 and ochratoxin A induced intestinal barrier disruption via the regulation of key differentially expressed microRNAs and long non-coding RNAs in BALB/c mice.
Nickel induces blood-testis barrier damage through ROS-mediated p38 MAPK pathways in mice.
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Dendrobium huoshanense Polysaccharide Improves High-Fat Diet Induced Liver Injury by Regulating the Gut-Liver Axis.
Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis.
Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury.
Refined Qingkailing protects the in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.
Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice.
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Cingulin regulates hair cell cuticular plate morphology and is required for hearing in human and mouse.
JNK regulates ciliogenesis through the interflagellar transport complex and actin networks.
Quercetin Attenuates the Combined Effects of Zearalenone and Lipopolysaccharide on IPEC-J2 Cell Injury through Activating the Nrf2 Signaling Pathway.
Cadmium promotes colorectal cancer metastasis through EGFR/Akt/mTOR signaling cascade and dynamics.
Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.
Environmental cadmium exposure facilitates mammary tumorigenesis via reprogramming gut microbiota-mediated glutamine metabolism in MMTV-Erbb2 mice.
Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling.
Phlorizin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota and Inhibiting Ferroptosis.
Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice.
Bile Acid Derivatives Effectively Prevented High-Fat Diet-Induced Colonic Barrier Dysfunction.
Comparative study of cigarette smoke, Klebsiella pneumoniae, and their combination on airway epithelial barrier function in mice.
Interleukin-1β suppresses rabies virus infection by activating cGAS-STING pathway and compromising the blood-brain barrier integrity in mice.
Globoside and the mucosal pH mediate parvovirus B19 entry through the epithelial barrier.
Oral Metal-Free Melanin Nanozymes for Natural and Durable Targeted Treatment of Inflammatory Bowel Disease (IBD).
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.
Shengjiang Xiexin Decoction ameliorates antibiotic-associated diarrhea by altering the gut microbiota and intestinal metabolic homeostasis.
The protective effects of electroacupuncture on intestinal barrier lesions in IBS and UC model.
HCMV Infection Reduces Nidogen-1 Expression, Contributing to Impaired Neural Rosette Development in Brain Organoids.
Gut Microbiota from Short-Chain Chlorinated Paraffin-Exposed Mice Promotes Astrocyte Activation by Disrupting the Intestinal Tight Junction via Zonulin Upregulation.
Baicalin Attenuates H(2)O(2)-Induced Oxidative Stress by Regulating the AMPK/Nrf2 Signaling Pathway in IPEC-J2 Cells.
Calcitriol, an Active Form of Vitamin D3, Mitigates Skin Barrier Dysfunction in Atopic Dermatitis NC/Nga Mice.
Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine.
Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions.
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Therapeutic mechanisms of the medicine and food homology formula Xiao-Ke-Yin on glucolipid metabolic dysfunction revealed by transcriptomics, metabolomics and microbiomics in mice.
Hydrogen inhalation ameliorates hepatic inflammation and modulates gut microbiota in rats with high-fat diet-induced non-alcoholic fatty liver disease.
Bazedoxifene attenuates intestinal injury in sepsis by suppressing the NF-κB/NLRP3 signaling pathways.
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
HC067047 Ameliorates Sepsis-associated Encephalopathy by Suppressing Endoplasmic Reticulum Stress and Oxidative Stress-Induced Pyroptosis in the Hippocampi of Mice.
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
A novel model of subretinal edema induced by DL-alpha aminoadipic acid.
The Polo-Like Kinase 1-Mammalian Target of Rapamycin Axis Regulates Autophagy to Prevent Intestinal Barrier Dysfunction During Sepsis.
S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung.
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation.
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Cimifugin suppresses type 2 airway inflammation by binding to SPR and regulating its protein expression in a non-enzymatic manner.
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis.
p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.
Integration of metabolomics and transcriptomics to reveal ferroptosis is involved in Tripterygium wilfordii polyglycoside tablet-induced testicular injury.
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Alteration of gut microbiome and metabolome by Clostridium butyricum can repair the intestinal dysbiosis caused by antibiotics in mice.
Emblica officinalis mitigates intestinal toxicity of mice by modulating gut microbiota in lead exposure.
Highly stable fibronectin-mimetic-peptide-based supramolecular hydrogel to accelerate corneal wound healing.
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression.
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Circulating exosomal miR-155-5p contributes to severe acute pancreatitis-associated intestinal barrier injury by targeting SOCS1 to activate NLRP3 inflammasome-mediated pyroptosis.
Tongqiao Huoxue Decoction ameliorates traumatic brain injury-induced gastrointestinal dysfunction by regulating CD36/15-LO/NR4A1 signaling, which fails when CD36 and CX3CR1 are deficient.
SRT1720 attenuates UVA-induced corneal endothelial damage via inhibition of oxidative stress and cellular apoptosis.
Dopamine D1 receptor agonist alleviates acute lung injury via modulating inflammatory responses in macrophages and barrier function in airway epithelial cells.
Spermidine protects intestinal mucosal barrier function in mice colitis via the AhR/Nrf2 and AhR/STAT3 signaling pathways.
YES-associated protein-regulated Smad7 worsen epithelial barrier injury of chronic sinusitis with nasal polyps.
Systematic assessment of hexavalent chromium-induced damage to male fertility and the preventive role of melatonin: a longitudinal study from the translational point of view.
Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice.
Non-Invasive and Label-Free On-Chip Impedance Monitoring of Heatstroke.
Fecal microbiota transplantation from sodium alginate-dosed mice and normal mice mitigates intestinal barrier injury and gut dysbiosis induced by antibiotics and cyclophosphamide.
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice.
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Polystyrene microplastics aggravate acute pancreatitis in mice.
MiR-26a-5p from HucMSC-derived extracellular vesicles inhibits epithelial mesenchymal transition by targeting Adam17 in silica-induced lung fibrosis.
Fluoride disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated RhoA/ROCK signaling and myosin light chain kinase.
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Effect of lonidamine derivatives on the inhibition of transformed cell area expansion.
Thioredoxin1 is a target to attenuate diabetes‑induced RPE cell dysfunction in human ARPE19 cells by alleviating oxidative stress.
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
Protective effects of melatonin on deoxynivalenol-induced oxidative stress and autophagy in IPEC-J2 cells.
Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases.
The ACE2 activator diminazene aceturate ameliorates colitis by repairing the gut-vascular barrier in mice.
Programmed cell death 10 increased blood-brain barrier permeability through HMGB1/TLR4 mediated downregulation of endothelial ZO-1 in glioblastoma.
Effects of the polypeptide from peanut meal mixed fermentation on lipid metabolism and intestinal flora of hyperlipidemic mice.
DSPE-PEG polymer enhanced berberine absorption specifically in the small intestine of rats through paracellular passway.
The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage.
Mn(3)O(4) Nanozyme Loaded Thermosensitive PDLLA-PEG-PDLLA Hydrogels for the Treatment of Inflammatory Bowel Disease.
Alginate oligosaccharide structures differentially affect DSS-induced colitis in mice by modulating gut microbiota.
Open source board based acoustofluidic transwells for reversible disruption of the blood-brain barrier for therapeutic delivery.
Mechanistic study for drug induced cholestasis using batch-fabricated 3D spheroids developed by agarose-stamping method.
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Hexavalent chromium disrupts the skin barrier by targeting ROS-mediated mitochondrial pathway apoptosis in keratinocytes.
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation.
Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury.
Apelin-13 prevents the effects of oxygen-glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT-mTOR signaling.
Metasilicate-based alkaline mineral water confers diarrhea resistance in maternally separated piglets via the microbiota-gut interaction.
Desulfovibrio desulfuricans aggravates atherosclerosis by enhancing intestinal permeability and endothelial TLR4/NF-κB pathway in Apoe (-/-) mice.
A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection.
FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
Effects of 6-Shogaol on Glucose Uptake and Intestinal Barrier Integrity in Caco-2 Cells.
Gut Bacterial Indole-3-acetic Acid Induced Immune Promotion Mediates Preventive Effects of Fu Brick Tea Polyphenols on Experimental Colitis.
Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions.
Intestinal epithelium penetration of liraglutide via cholic acid pre-complexation and zein/rhamnolipids nanocomposite delivery.
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota.
Involvement of gut-brain communication in arsenite-induced neurobehavioral impairments in adult male mice.
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Effects of Buyang Huanwu Decoction on Intestinal Barrier, Intestinal Flora, and Trimethylamine Oxide in Rats with Heart Failure.
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses.
Capsaicin shapes gut microbiota and pre-metastatic niche to facilitate cancer metastasis to liver.
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
PLK1 protects intestinal barrier function in sepsis: A translational research.
DHA-enriched phosphatidylserine alleviates high fat diet-induced jejunum injury in mice by modulating gut microbiota.
Lutein Prevents Liver Injury and Intestinal Barrier Dysfunction in Rats Subjected to Chronic Alcohol Intake.
Fecal microbiota transplantation attenuates Escherichia coli infected outgrowth by modulating the intestinal microbiome.
Small molecule compound K-7174 attenuates neuropsychiatric manifestations in lupus-prone mice.
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.
Effects of Houpo Mahuang Decoction on serum metabolism and TRPV1/Ca(2+)/TJs in asthma.
Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE-19 Cells.
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Toxicity assessment of organophosphate flame retardant triphenyl phosphate (TPHP) on intestines in mice.
Increased R-spondin 3 contributes to aerobic exercise-induced protection against renal vascular endothelial hyperpermeability and acute kidney injury.
Deciphering the interplay between LPS/TLR4 pathways, neurotransmitter, and deltamethrin-induced depressive-like behavior: Perspectives from the gut-brain axis.
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
The E3 ubiquitin ligase RNF31 mediates the development of ulcerative colitis by regulating NLRP3 inflammasome activation.
Ursodeoxycholic acid alleviates sepsis-induced lung injury by blocking PANoptosis via STING pathway.
Combined VEGF and bFGF loaded nanofiber membrane protects against neuronal injury and hypomyelination in a rat model of chronic cerebral hypoperfusion.
Protective effect of ethyl ferulate against hypoxic injury in retinal cells and retinal neovascularization in an oxygen-induced retinopathy model.
Dual-Targeted Nanoparticle-in-Microparticle System for Ulcerative Colitis Therapy.
Effects of enteral nutrition supplemented with octanoic acid on lipopolysaccharide-induced intestinal injury: role of peroxisome proliferator-activated receptor γ/STAT-1/myeloid differentiation factor 88 pathway.
Plasma-Activated Solutions Mitigates DSS-Induced Colitis via Restoring Redox Homeostasis and Reversing Microbiota Dysbiosis.
IGF2/IGF2R/Sting signaling as a therapeutic target in DSS-induced ulcerative colitis.
FGF21 alleviates endothelial mitochondrial damage and prevents BBB from disruption after intracranial hemorrhage through a mechanism involving SIRT6.
Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells.
Bacterial butyrate mediates the anti-atherosclerotic effect of silybin.
Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis and Ameliorates Colitis.
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP.
Clostridium butyricum and Clostridium tyrobutyricum: angel or devil for necrotizing enterocolitis?
Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients.
Gut microbiota-associated taurine metabolism dysregulation in a mouse model of Parkinson's disease.
Beta-Amyloid Enhances Vessel Formation in Organotypic Brain Slices Connected to Microcontact Prints.
Heat Stress-Induced Fetal Intrauterine Growth Restriction Is Associated with Elevated LPS Levels Along the Maternal Intestine-Placenta-Fetus Axis in Pregnant Mice.
2'-Fucosyllactose alleviates OVA-induced food allergy in mice by ameliorating intestinal microecology and regulating the imbalance of Th2/Th1 proportion.
The role of ROS-pyroptosis in PM(2.5) induced air-blood barrier destruction.
Maternal Selenium-Enriched Yeast Supplementation in Sows Enhances Offspring Growth and Antioxidant Status through the Nrf2/Keap1 Pathway.
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function.
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Succinate signaling attenuates high-fat diet-induced metabolic disturbance and intestinal barrier dysfunction.
Limosilactobacillus fermentum NCU003089 and Lactiplantibacillus plantarum NCU001261, two probiotics with inhibition of Escherichia coli and Cronobacter sakazakii translocation in vitro.
Sphingosine 1-phosphate receptor 1 regulates blood-brain barrier permeability in epileptic mice.
Triclocarban exposure aggravates dextran sulfate sodium-induced colitis by deteriorating the gut barrier function and microbial community in mice.
MiR-874-5p targets VDR/NLRP3 to reduce intestinal pyroptosis and improve intestinal barrier damage in sepsis.
Extracellular ATP accelerates cell death and decreases tight junction protein ZO-1 in hypoxic cochlear strial marginal cells in neonatal rats.
Arula-7 powder improves diarrhea and intestinal epithelial tight junction function associated with its regulation of intestinal flora in calves infected with pathogenic Escherichia coli O(1).
Mechanisms of Lung and Intestinal Microbiota and Innate Immune Changes Caused by Pathogenic Enterococcus Faecalis Promoting the Development of Pediatric Pneumonia.
Zinc-Rutin Particles Ameliorate DSS-Induced Acute and Chronic Colitis via Anti-inflammatory and Antioxidant Protection of the Intestinal Epithelial Barrier.
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis.
Dextran sulfate sodium-induced mild chronic colitis induced cognitive impairment accompanied by inhibition of neuronal maturation in adolescent mice.
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition.
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
Mechanisms of Qingyi Decoction in Severe Acute Pancreatitis-Associated Acute Lung Injury via Gut Microbiota: Targeting the Short-Chain Fatty Acids-Mediated AMPK/NF-κB/NLRP3 Pathway.
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice.
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
A mesoporous polydopamine-derived nanomedicine for targeted and synergistic treatment of inflammatory bowel disease by pH-Responsive drug release and ROS scavenging.
Intranasal Delivery of Gene-Edited Microglial Exosomes Improves Neurological Outcomes after Intracerebral Hemorrhage by Regulating Neuroinflammation.
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Organotypic 3D Co-Culture of Human Pleura as a Novel In Vitro Model of Staphylococcus aureus Infection and Biofilm Development.
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis.
Huangkui capsule alleviates doxorubicin-induced proteinuria via protecting against podocyte damage and inhibiting JAK/STAT signaling.
Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver disease in high-fat diet-induced obese mice.
Cadmium-induced Sertoli Cell Injury Through p38-MAPK and Related Signaling Proteins-A Study by RNA Sequencing.
Lactational exposure to Deoxynivalenol causes mammary gland injury via inducing inflammatory response and impairing blood-milk barrier integrity in mice.
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Mitochondrial-targeting fluorescent small molecule IR-780 alleviates radiation-induced brain injury.
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
Construction of a three-dimensional urothelium on-chip with barrier function based on urinary flow microenvironment.
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Kinase Activity Is Not Required for G Protein-Coupled Receptor Kinase 4 Restraining mTOR Signaling during Cilia and Kidney Development.
A leaky human colon model reveals uncoupled apical/basal cytotoxicity in early Clostridioides difficile toxin exposure.
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Selenoprotein W Ameliorates Experimental Colitis and Promotes Intestinal Epithelial Repair.
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Probiotic Lactobacillus rhamnosus GR-1 supplementation attenuates Pb-induced learning and memory deficits by reshaping the gut microbiota.
Lactobacillus fermentum CECT5716 Alleviates the Inflammatory Response in Asthma by Regulating TLR2/TLR4 Expression.
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Blue Light Induces RPE Cell Necroptosis, Which Can Be Inhibited by Minocycline.
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
Bacteroides fragilis strain ZY-312 promotes intestinal barrier integrity via upregulating the STAT3 pathway in a radiation-induced intestinal injury mouse model.
Tannic acid attenuates intestinal oxidative damage by improving antioxidant capacity and intestinal barrier in weaned piglets and IPEC-J2 cells.
Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.
Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Effects of Lipolysis-Stimulated Lipoprotein Receptor on Tight Junctions of Pancreatic Ductal Epithelial Cells in Hypertriglyceridemic Acute Pancreatitis.
Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway.
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
The effect of a fennel seed extract on the STAT signaling and intestinal barrier function.
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
The SARS-CoV-2 envelope protein disrupts barrier function in an in vitro human blood-brain barrier model.
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage.
Selenium-enriched Bifidobacterium longum DD98 effectively ameliorates dextran sulfate sodium-induced ulcerative colitis in mice.
Preventive effects of the Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple on chronic kidney disease rats via modulating the intestinal microbiota and enhancing the intestinal barrier.
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway.
Tryptophan Supplementation Enhances Intestinal Health by Improving Gut Barrier Function, Alleviating Inflammation, and Modulating Intestinal Microbiome in Lipopolysaccharide-Challenged Piglets.
Qingchang Wenzhong Decoction Prevents the Occurrence of Intestinal Tumors by Regulating Intestinal Microbiota and Gasdermin E.
Integrated analysis of inflammatory response subtype-related signature to predict clinical outcomes, immune status and drug targets in lower-grade glioma.
Effect of Tanshinone IIA on Gut Microbiome in Diabetes-Induced Cognitive Impairment.
Shenling Baizhu Powder Alleviates TNBS-Induced Colitis in Rats by Improving Intestinal Epithelial Permeability and Inhibiting Inflammation Through the TLR5/MyD88/NF-κB Pathway.
Transepithelial Secretion of Mucosal IgM Mediated by Polymeric Immunoglobulin Receptor of Flounder (Paralichthys olivaceus): In-Vivo and In-Vitro Evidence.
Artemisinin analog SM934 alleviates epithelial barrier dysfunction via inhibiting apoptosis and caspase-1-mediated pyroptosis in experimental colitis.
Human Fecal Microbiota Transplantation Reduces the Susceptibility to Dextran Sulfate Sodium-Induced Germ-Free Mouse Colitis.
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis.
Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis.
Liujunanwei decoction attenuates cisplatin-induced nausea and vomiting in a Rat-Pica model partially mediated by modulating the gut micsrobiome.
Correlation Analysis of Gut Microbiota and Serum Metabolome With Porphyromonas gingivalis-Induced Metabolic Disorders.
Effects of Zhishi Daozhi Decoction on the intestinal flora of nonalcoholic fatty liver disease mice induced by a high-fat diet.
Telomerase reverse transcriptase promotes angiogenesis in neonatal rats after hypoxic-ischemic brain damage.
A Platform for Co-Culture of Primary Human Colonic Epithelium With Anaerobic Probiotic Bacteria.
Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis.
Complement factor B inhibitor LNP023 improves lupus nephritis in MRL/lpr mice.
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells.
Exercise protects intestinal epithelial barrier from high fat diet- induced permeabilization through SESN2/AMPKα1/HIF-1α signaling.
Glutamine in suppression of lipopolysaccharide-induced piglet intestinal inflammation: The crosstalk between AMPK activation and mitochondrial function.
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions.
Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities.
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Protective Effects and Mechanism of a Novel Probiotic Strain Ligilactobacillus salivarius YL20 against Cronobacter sakazakii-Induced Necrotizing Enterocolitis In Vitro and In Vivo.
Effect and Mechanism of Pharmaceutical Excipients on Berberine to Alleviate Ulcerative Colitis via Regulating Gut Microbiota.
Phytic Acid Improves Hepatic Steatosis, Inflammation, and Oxidative Stress in High-Fat Diet (HFD)-Fed Mice by Modulating the Gut-Liver Axis.
Periplaneta americana Extract Pretreatment Alleviates Oxidative Stress and Inflammation and Increases the Abundance of Gut Akkermansia muciniphila in Diquat-Induced Mice.
Mo(3)Se(4) nanoparticle with ROS scavenging and multi-enzyme activity for the treatment of DSS-induced colitis in mice.
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Chromatin remodeler Znhit1 controls bone morphogenetic protein signaling in embryonic lung tissue branching.
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Rice Protein Peptides Alleviate Dextran Sulfate Sodium-Induced Colitis via the Keap1-Nrf2 Signaling Pathway and Regulating Gut Microbiota.
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Network Pharmacology Analysis and Experimental Validation of Kaempferol in the Treatment of Ischemic Stroke by Inhibiting Apoptosis and Regulating Neuroinflammation Involving Neutrophils.
Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema.
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice.
Restored intestinal integrity, nutrients transporters, energy metabolism, antioxidative capacity and decreased harmful microbiota were associated with IUGR piglet's catch-up growth before weanling.
Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice.
P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy.
Betaine Ameliorates Acute Sever Ulcerative Colitis by Inhibiting Oxidative Stress Induced Inflammatory Pyroptosis.
Suspended Collagen Hydrogels to Replicate Human Colonic Epithelial Cell Interactions with Immune Cells.
Metabolites of Latilactobacillus curvatus BYB3 and Indole Activate Aryl Hydrocarbon Receptor to Attenuate Lipopolysaccharide-Induced Intestinal Barrier Dysfunction.
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Neutrophil extracellular traps: A novel therapeutic target for intracranial hemorrhage.
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Xiaojianzhong decoction attenuates gastric mucosal injury by activating the p62/Keap1/Nrf2 signaling pathway to inhibit ferroptosis.
Luteolin alleviates ulcerative colitis by restoring the balance of NCR(-)ILC3/NCR(+)ILC3 to repairing impaired intestinal barrier.
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Hypoxia-Induced HIF-1α Expression Promotes Neurogenic Bladder Fibrosis via EMT and Pyroptosis.
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway.
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
FGF2 isoforms play distinct roles in tubular epithelial-to-mesenchymal transition in diabetic nephropathy.
Gestational PCB52 exposure induces hepatotoxicity and intestinal injury by activating inflammation in dam and offspring mice: A maternal and progeny study.
DHA-enriched phosphatidylcholine from Clupea harengus roes regulates the gut-liver axis to ameliorate high-fat diet-induced non-alcoholic fatty liver disease.
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury.
Galactooligosaccharides as a protective agent for intestinal barrier and its regulatory functions for intestinal microbiota.
Effect of dendrobium mixture in alleviating diabetic cognitive impairment associated with regulating gut microbiota.
Comparison of five diarrhea-predominant irritable bowel syndrome (IBS-D) rat models in the brain-gut-microbiota axis.
miR-145-5p targets MMP2 to protect brain injury in hypertensive intracerebral hemorrhage via inactivation of the Wnt/β-catenin signaling pathway.
Human branching cholangiocyte organoids recapitulate functional bile duct formation.
Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.
JAC4 Protects from X-ray Radiation-Induced Intestinal Injury by JWA-Mediated Anti-Oxidation/Inflammation Signaling.
Chromogranin A-derived peptide CGA47-66 protects against septic brain injury by reducing blood-brain barrier damage through the PI3K/AKT pathway.
Methamphetamine induces intestinal injury by altering gut microbiota and promoting inflammation in mice.
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
Phloretin Protects Bovine Rumen Epithelial Cells from LPS-Induced Injury.
Gestational exposure to GenX induces hepatic alterations by the gut-liver axis in maternal mice: A similar mechanism as PFOA.
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Astilbin from Smilax glabra Roxb. alleviates high-fat diet-induced metabolic dysfunction.
Diet composition affects long-term zearalenone exposure on the gut-blood-liver axis metabolic dysfunction in mice.
Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats.
Dietary ferulic acid and vanillic acid on inflammation, gut barrier function and growth performance in lipopolysaccharide-challenged piglets.
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats.
M1 macrophages impair tight junctions between endothelial cells after spinal cord injury.
Alterations in the expression level of visfatin in the lungs of piglets infected with PRRSV and its effect on PRRSV replication.
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Apple polyphenol extract modulates bile acid metabolism and gut microbiota by regulating the circadian rhythms in daytime-restricted high fat diet feeding C57BL/6 male mice.
Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway.
Bioactive triple peptide inhibits inflammasome activation to alleviate Salmonella-induced intestinal inflammation in mice via modulation of host defense and bacterial virulence.
Effect of TRAF6 in acute pancreatitis-induced intestinal barrier injury via TLR4/NF-κB signal pathway.
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Inhibition of galectin-3 ameliorates high-glucose-induced oxidative stress and inflammation in ARPE-19 cells.
Effects of dietary lycopene supplementation on intestinal morphology, antioxidant capability and inflammatory response in finishing pigs.
DEHP induces ferroptosis in testes via p38α-lipid ROS circulation and destroys the BTB integrity.
Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis.
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Aryl-hydrocarbon receptor-interacting protein regulates tumorigenic and metastatic properties of colorectal cancer cells driving liver metastasis.
Atractyloside-A ameliorates spleen deficiency diarrhea by interfering with TLR4/MyD88/NF-κB signaling activation and regulating intestinal flora homeostasis.
Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy.
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Longitudinal 16S rRNA Sequencing Reveals Relationships among Alterations of Gut Microbiota and Nonalcoholic Fatty Liver Disease Progression in Mice.
Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia.
Periodontitis may induce gut microbiota dysbiosis via salivary microbiota.
Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.
Analysis by transcriptomics and metabolomics for the proliferation inhibition and dysfunction through redox imbalance-mediated DNA damage response and ferroptosis in male reproduction of mice and TM4 Sertoli cells exposed to PM(2.5).
Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery.
Oxidized PUFAs Increase Susceptibility of Mice to Salmonella Infection by Diminishing Host's Innate Immune Responses.
Burn Injury-Induced Extracellular Vesicle Production and Characteristics.
Breast Cancer Stem Cells-derived Extracellular Vesicles Affect PPARG Expression by Delivering MicroRNA-197 in Breast Cancer Cells.
Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis.
Protective role of casuarinin from Melastoma malabathricum against a mouse model of 5-fluorouracil-induced intestinal mucositis: Impact on inflammation and gut microbiota dysbiosis.
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia.
Human 2D Crypt Model for Assaying Intestinal Stem Cell Proliferation and Differentiation.
Neuroprotective Effects of Chlorogenic Acid in a Mouse Model of Intracerebral Hemorrhage Associated with Reduced Extracellular Matrix Metalloproteinase Inducer.
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Delayed administration of nafamostat mesylate inhibits thrombin-mediated blood-spinal cord barrier breakdown during acute spinal cord injury in rats.
Effect of Houpo-Mahuang Decoction on aggravated asthma induced by cigarette smoke and the expression of TRPA1 and tight junctions in mice.
Metformin protects against pericyte apoptosis and promotes neurogenesis through suppressing JNK p38 MAPK signalling activation in ischemia/reperfusion injury.
Bryodulcosigenin a natural cucurbitane-type triterpenoid attenuates dextran sulfate sodium (DSS)-induced colitis in mice.
Radiocontrast agent and intraductal pressure promote the progression of post-ERCP pancreatitis by regulating inflammatory response, cellular apoptosis, and tight junction integrity.
A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury.
Enterococcus faecium HDRsEf1 inhibits Lipopolysaccharide-induced downregulation of zona occludens -1 expression via toll-like receptor 2/4-mediated c-Jun N-terminal kinase/activator protein-1 signalling pathways.
Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis.
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Apple polyphenols improve intestinal barrier function by enhancing antioxidant capacity and suppressing inflammation in weaning piglets.
Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue.
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
Online Measurement System for Dynamic Flow Bioreactors to Study Barrier Integrity of hiPSC-Based Blood-Brain Barrier In Vitro Models.
De novo Lipogenesis in Astrocytes Promotes the Repair of Blood-Brain Barrier after Transient Cerebral Ischemia Through Interleukin-33.
Protective effects of polysaccharides from Atractylodes macrocephalae Koidz. against dextran sulfate sodium induced intestinal mucosal injury on mice.
Identifying distinct oxygen diffusivity through type I pneumocyte-like cell layers using microfluidic device.
Cordycepin, a major bioactive component of Cordyceps militaris, ameliorates diabetes-induced testicular damage through the Sirt1/Foxo3a pathway.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Oral delivery of decanoic acid conjugated plant protein shell incorporating hybrid nanosystem leverage intestinal absorption of polyphenols.
MicroRNA-582-5p regulates cell invasion in bladder cancer through targeting Forkhead Box G1.
Hyperglycemia induces corneal endothelial dysfunction through attenuating mitophagy.
Connexin32 ameliorates epithelial-to-mesenchymal-transition in diabetic renal tubular via inhibiting NOX4.
CRH/CRHR1 modulates cerebrovascular endothelial cell permeability in association with S1PR2 and S1PR3 under oxidative stress.
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Effects of Exopolysaccharides from Lactiplantibacillus plantarum JLAU103 on Intestinal Immune Response, Oxidative Stress, and Microbial Communities in Cyclophosphamide-Induced Immunosuppressed Mice.
Akkermansia muciniphila Ameliorates Acetaminophen-Induced Liver Injury by Regulating Gut Microbial Composition and Metabolism.
LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland.
LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice.
A Pilot Application of an iTRAQ-Based Proteomics Screen Estimates the Effects of Cigarette Smokers' Serum on RPE Cells With AMD High-Risk Alleles.
Effects of dietary dihydromyricetin supplementation on intestinal barrier and humoral immunity in growing-finishing pigs.
Hesperidin partly ameliorates the decabromodiphenyl ether-induced reproductive toxicity in pubertal mice.
Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.
Polysaccharide ORP-1 isolated from Oudemansiella raphanipes ameliorates age-associated intestinal epithelial barrier dysfunction in Caco-2 cells monolayer.
Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiation.
Dahuang Mudan decoction repairs intestinal barrier in chronic colitic mice by regulating the function of ILC3.
Glutathione Protects against Paraquat-Induced Oxidative Stress by Regulating Intestinal Barrier, Antioxidant Capacity, and CAR Signaling Pathway in Weaned Piglets.
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Effect of ginsenoside compound K on alleviating colitis via modulating gut microbiota.
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo.
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury.
Exploration of the mechanisms underlying the beneficial effect of Luo Tong formula on retinal function in diabetic rats via the "gut microbiota-inflammation-retina" axis.
Intermittent Fasting Alleviates Risk Markers in a Murine Model of Ulcerative Colitis by Modulating the Gut Microbiome and Metabolome.
The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response.
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Effects of chitosan oligosaccharides (COS) and FMT from COS-dosed mice on intestinal barrier function and cell apoptosis.
Microglia Regulate Blood-Brain Barrier Integrity via MiR-126a-5p/MMP9 Axis during Inflammatory Demyelination.
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis.
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Pyroptosis participates in PM(2.5)-induced air-blood barrier dysfunction.
Chitosan-modified Phellinus igniarius polysaccharide PLGA nanoparticles ameliorated inflammatory bowel disease.
Comparative Effects of Allulose, Fructose, and Glucose on the Small Intestine.
Tollip Orchestrates Macrophage Polarization to Alleviate Intestinal Mucosal Inflammation.
Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.
Protective effect of surface-layer proteins from four Lactobacillus strains on tumor necrosis factor-α-induced intestinal barrier dysfunction.
Neohesperidin Dihydrochalcone Ameliorates High-Fat Diet-Induced Glycolipid Metabolism Disorder in Rats.
Wumei pills attenuates 5-fluorouracil-induced intestinal mucositis through Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB pathway and microbiota regulation.
Stigmasterol attenuates hepatic steatosis in rats by strengthening the intestinal barrier and improving bile acid metabolism.
Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood-brain barrier disruption.
[Diethylhexyl phthalate induces anxiety-like behavior and learning and memory impairment in mice probably by damaging blood-brain barrier].
Ascorbic acid induces salivary gland function through TET2/acetylcholine receptor signaling in aging SAMP1/Klotho (-/-) mice.
Urolithin A attenuates arsenic-induced gut barrier dysfunction.
Curcumin Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice Through Regulating Gut Microbiota.
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.
Dietary ferulic acid supplementation improves intestinal antioxidant capacity and intestinal barrier function in weaned piglets.
Mesencephalic astrocyte-derived neurotrophic factor restores blood-brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway.
Gelsolin impairs barrier function in pancreatic ductal epithelial cells by actin filament depolymerization in hypertriglyceridemia-induced pancreatitis in vitro.
Interfering with alternatively activated macrophages by CSF-1R inhibition exerts therapeutic capacity on allergic airway inflammation.
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Late-onset hearing loss case associated with a heterozygous truncating variant of DIAPH1.
Industrially Produced Rice Protein Ameliorates Dextran Sulfate Sodium-Induced Colitis via Protecting the Intestinal Barrier, Mitigating Oxidative Stress, and Regulating Gut Microbiota.
Anemone chinensis Bunge aqueous enema alleviates dextran sulfate sodium-induced colitis via inhibition of inflammation and regulation of the colonic mucosal microbiota.
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.
Comparison of the effects of different calorie amounts of enteral nutrition in hypercatabolism associated with ghrelin-POMC in endotoxemic rats.
Sertoli cell and spermatogonial development in pigs.
Ubiquitin-Specific Protease 25 Aggravates Acute Pancreatitis and Acute Pancreatitis-Related Multiple Organ Injury by Destroying Tight Junctions Through Activation of The STAT3 Pathway.
Cathelicidin-WA Protects Against LPS-Induced Gut Damage Through Enhancing Survival and Function of Intestinal Stem Cells.
P16 (I NK 4a) Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice.
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Bovine Lactoferrin Protects Dextran Sulfate Sodium Salt Mice Against Inflammation and Impairment of Colonic Epithelial Barrier by Regulating Gut Microbial Structure and Metabolites.
Effects of Guava (Psidium guajava L.) Leaf Extract on the Metabolomics of Serum and Feces in Weaned Piglets Challenged by Escherichia coli.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via Activation of Peribiliary Glands through the Wnt Pathway.
Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota.
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1(-/-) Mice.
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Overexpression of 15-Hydroxyprostaglandin Dehydrogenase Inhibits A549 Lung Adenocarcinoma Cell Growth via Inducing Cell Cycle Arrest and Inhibiting Epithelial-Mesenchymal Transition.
Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.
Evaluation of the Anti-Aging Effects of a Probiotic Combination Isolated From Centenarians in a SAMP8 Mouse Model.
Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury.
Integrated Analysis of the Cecal Microbiome and Plasma Metabolomics to Explore NaoMaiTong and Its Potential Role in Changing the Intestinal Flora and Their Metabolites in Ischemic Stroke.
Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma.
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
The Panda-Derived Lactobacillus plantarum G201683 Alleviates the Inflammatory Response in DSS-Induced Panda Microbiota-Associated Mice.
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis.
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization.
Susceptibility of Human Airway Tissue Models Derived From Different Anatomical Sites to Bordetella pertussis and Its Virulence Factor Adenylate Cyclase Toxin.
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Neutrophil extracellular traps induce thrombogenicity in severe carotid stenosis.
The important roles and molecular mechanisms of annexin A(2) autoantibody in children with nephrotic syndrome.
Enteromorpha polysaccharide-zinc replacing prophylactic antibiotics contributes to improving gut health of weaned piglets.
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Magnetically-propelled fecal surrogates for modeling the impact of solid-induced shear forces on primary colonic epithelial cells.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Mfsd2a overexpression alleviates vascular dysfunction in diabetic retinopathy.
Treatment of early brain injury after subarachnoid hemorrhage in the rat model by inhibiting p53-induced ferroptosis.
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure.
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Regulation of blood-brain barrier permeability by Salvinorin A via alleviating endoplasmic reticulum stress in brain endothelial cell after ischemia stroke.
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Improved epithelial cell-cell adhesion using molecular mobility of supramolecular surfaces.
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply.
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Seaweed polysaccharide mitigates intestinal barrier dysfunction induced by enterotoxigenic Escherichia coli through NF-κB pathway suppression in porcine intestinal epithelial cells.
Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting the intestinal barrier, mitigating oxidative stress and regulating the gut microbiota.
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation.
Neuroprotection of minocycline by inhibition of extracellular matrix metalloproteinase inducer expression following intracerebral hemorrhage in mice.
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Interleukin-9 promotes intestinal barrier injury of sepsis: a translational research.
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.
Naringenin attenuates experimental autoimmune encephalomyelitis by protecting the intact of blood-brain barrier and controlling inflammatory cell migration.
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
l-Arabinose Attenuates Gliadin-Induced Food Allergy via Regulation of Th1/Th2 Balance and Upregulation of Regulatory T Cells in Mice.
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice.
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
A Microfluidic Multisize Spheroid Array for Multiparametric Screening of Anticancer Drugs and Blood-Brain Barrier Transport Properties.
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut-Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation.
Brain endothelial LRP1 maintains blood-brain barrier integrity.
Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNFα-promotes severe intestinal epithelial dysfunction.
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Xiao-Xu-Ming decoction prevented hemorrhagic transformation induced by acute hyperglycemia through inhibiting AGE-RAGE-mediated neuroinflammation.
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
Effects of cigarette smoke on the aggravation of ovalbumin-induced asthma and the expressions of TRPA1 and tight junctions in mice.
A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.
Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.
Effects of Coated Cysteamine on Oxidative Stress and Inflammation in Weaned Pigs.
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Roux-en-Y gastric bypass potentially improved intestinal permeability by regulating gut innate immunity in diet-induced obese mice.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Meningitic Escherichia coli α-hemolysin aggravates blood-brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling.
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling.
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Scratching damages tight junctions through the Akt-claudin 1 axis in atopic dermatitis.
CD151 Alleviates Early Blood-Brain Barrier Dysfunction After Experimental Focal Brain Ischemia in Rats.
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice.
A Comparison of Chitosan, Mesoporous Silica and Poly(lactic-co-glycolic) Acid Nanocarriers for Optimising Intestinal Uptake of Oral Protein Therapeutics.
Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice.
Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.
Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.
Effects of Pinus massoniana pollen polysaccharides on intestinal microenvironment and colitis in mice.
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
Polystyrene microplastics induced male reproductive toxicity in mice.
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Antibiotic-induced microbiome depletion in adult mice disrupts blood-brain barrier and facilitates brain infiltration of monocytes after bone-marrow transplantation.
Punicalagin Prevents Hepatic Steatosis through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western Diet-Fed Mice.
First evidence of altered microbiota and intestinal damage and their link to absence epilepsy in a genetic animal model, the WAG/Rij rat.
Val-Val-Tyr-Pro protects against non-alcoholic steatohepatitis in mice by modulating the gut microbiota and gut-liver axis activation.
Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis.
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Induction of Epithelial-mesenchymal Transition in MDCK II Cells.
Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.
Galli gigeriae endothelium corneum: its intestinal barrier protective activity in vitro and chemical composition.
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Neutrophil extracellular traps induce a hypercoagulable state in glioma.
Salidroside protects against ventilation-induced lung injury by inhibiting the expression of matrix metalloproteinase-9.
Poly(ADP-ribose) polymerase inhibitor PJ34 protects against UVA-induced oxidative damage in corneal endothelium.
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Modified cyclodextrin-based nanoparticles mediated delivery of siRNA for huntingtin gene silencing across an in vitro BBB model.
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
Djulis Hull Improves Insulin Resistance and Modulates the Gut Microbiota in High-Fat Diet (HFD)-Induced Hyperglycaemia.
Dose-Dependent Relationship between Protection of Thioacetamide-Induced Acute Liver Injury and Hyperammonemia and Concentration of Lactobacillus salivarius Li01 in Mice.
Titanium dioxide nanoparticles perturb the blood-testis barrier via disruption of actin-based cell adhesive function.
Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice.
Intrahepatic cholestasis induced by α-naphthylisothiocyanate can cause gut-liver axis disorders.
LncRNA-MALAT1/miRNA-204-5p/Smad4 Axis Regulates Epithelial-Mesenchymal Transition, Proliferation and Migration of Lens Epithelial Cells.
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.
Effects of Dietary Supplementation of Algae-Derived Polysaccharides on Morphology, Tight Junctions, Antioxidant Capacity and Immune Response of Duodenum in Broilers under Heat Stress.
Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets.
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Multiple roles of FGF10 in the regulation of corneal endothelial wound healing.
Effects of the extract from peanut meal fermented with Bacillus natto and Monascus on lipid metabolism and intestinal barrier function of hyperlipidemic mice.
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Transwell Insert-Embedded Microfluidic Devices for Time-Lapse Monitoring of Alveolar Epithelium Barrier Function under Various Stimulations.
Impaired Colonic Contractility and Intestinal Permeability in Symptomatic Uncomplicated Diverticular Disease.
Exosomes derived from HeLa cells break down vascular integrity by triggering endoplasmic reticulum stress in endothelial cells.
Molecular mechanism mediating enteric bacterial translocation after severe burn: the role of cystic fibrosis transmembrane conductance regulator.
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation.
Teasaponin Ameliorates Murine Colitis by Regulating Gut Microbiota and Suppressing the Immune System Response.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway.
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated Nucleotide Binding Oligomerization Domain-Like Receptor Protein 3 Inflammasome Activation in Retinopathy Induced by Hyperglycemia.
Screening, Safety Evaluation, and Mechanism of Two Lactobacillus fermentum Strains in Reducing the Translocation of Staphylococcus aureus in the Caco-2 Monolayer Model.
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Taurine Alleviates Intestinal Injury by Mediating Tight Junction Barriers in Diquat-Challenged Piglet Models.
Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells.
1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation In Vivo and In Vitro Model.
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.
Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae.
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids.
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening.
Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice.
Bioinformatics analysis of LINC01554 and its co‑expressed genes in hepatocellular carcinoma.
Protective effect of Lactobacillus salivarius Li01 on thioacetamide-induced acute liver injury and hyperammonaemia.
Anthocyanins decrease the internalization of TiO(2) nanoparticles into 3D Caco-2 spheroids.
Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.
Novel Pentapeptide Derived from Chicken by-Product Ameliorates DSS-Induced Colitis by Enhancing Intestinal Barrier Function via AhR-Induced Src Inactivation.
Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress.
Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway.
Effect of MicroRNA-126a-3p on Bone Marrow Mesenchymal Stem Cells Repairing Blood-brain Barrier and Nerve Injury after Intracerebral Hemorrhage.
Small airway remodeling in diabetic and smoking chronic obstructive pulmonary disease patients.
Exposure to nonylphenol in early life increases pro-inflammatory cytokines in the prefrontal cortex: Involvement of gut-brain communication.
Palmitic Acid Affects Intestinal Epithelial Barrier Integrity and Permeability In Vitro.
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions.
Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia.
A PTAL-miR-101-FN1 Axis Promotes EMT and Invasion-Metastasis in Serous Ovarian Cancer.
Jiao-tai-wan inhibits inflammation of the gut-brain-axis and attenuates cognitive impairment in insomnic rats.
Methamphetamine-induced alterations in intestinal mucosal barrier function occur via the microRNA-181c/ TNF-α/tight junction axis.
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way.
CD147 Promoted Epithelial Mesenchymal Transition in Airway Epithelial Cells Induced by Cigarette Smoke via Oxidative Stress Signaling Pathway.
microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.
ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch.
Ursodeoxycholic Acid Halts Pathological Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy.
Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease.
TBC1D20 Is Essential for Mouse Blood-Testis Barrier Integrity Through Maintaining the Epithelial Phenotype and Modulating the Maturation of Sertoli Cells.
Platelet regulates neuroinflammation and restores blood-brain barrier integrity in a mouse model of traumatic brain injury.
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Identification of differentially expressed genes and signaling pathways involved in endometriosis by integrated bioinformatics analysis.
Protective Effect of Naringin on In Vitro Gut-Vascular Barrier Disruption of Intestinal Microvascular Endothelial Cells Induced by TNF-α.
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion.
Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Melatonin protects the mouse testis against heat-induced damage.
Peripheral inflammation promotes brain tau transmission via disrupting blood-brain barrier.
Environmental lead exposure aggravates the progression of Alzheimer's disease in mice by targeting on blood brain barrier.
Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice.
Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats.
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Icariside II attenuates cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction in rats via regulating the balance of MMP9/TIMP1.
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice.
Polysaccharide from the seeds of Plantago asiatica L. alleviates nonylphenol induced intestinal barrier injury by regulating tight junctions in human Caco-2 cell line.
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain.
Salvianolic acid B protects against myocardial ischaemia-reperfusion injury in rats via inhibiting high mobility group box 1 protein expression through the PI3K/Akt signalling pathway.
A self-driven bioinspired nanovehicle by leukocyte membrane-hitchhiking for early detection and treatment of atherosclerosis.
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Metformin therapy confers cardioprotection against the remodeling of gap junction in tachycardia-induced atrial fibrillation dog model.
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice.
Protective effect of Dioscorea zingiberensis ethanol extract on the disruption of blood-testes barrier in high-fat diet/streptozotocin-induced diabetic mice by upregulating ZO-1 and Nrf2.
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage.
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis.
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage.
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Building a Thick Mucus Hydrogel Layer to Improve the Physiological Relevance of In Vitro Primary Colonic Epithelial Models.
Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds.
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis.
High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis.
Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking.
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Licochalcone A Protects the Blood-Milk Barrier Integrity and Relieves the Inflammatory Response in LPS-Induced Mastitis.
Administration of Akkermansia muciniphila Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1.
Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection.
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro.
The effects of c-Src kinase on EMT signaling pathway in human lens epithelial cells associated with lens diseases.
An in vitro intestinal platform with a self-sustaining oxygen gradient to study the human gut/microbiome interface.
The protective effect of selenium from heat stress-induced porcine small intestinal epithelial cell line (IPEC-J2) injury is associated with regulation expression of selenoproteins.
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Chitosan coating of zein-carboxymethylated short-chain amylose nanocomposites improves oral bioavailability of insulin in vitro and in vivo.
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
TIMM50 promotes tumor progression via ERK signaling and predicts poor prognosis of non-small cell lung cancer patients.
Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway.
Activation of SIRT1 ameliorates LPS-induced lung injury in mice via decreasing endothelial tight junction permeability.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Propofol Protects Lung Endothelial Barrier Function by Suppression of High-Mobility Group Box 1 (HMGB1) Release and Mitochondrial Oxidative Damage Catalyzed by HMGB1.
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Epidermal growth factor treatment has protective effects on the integrity of the blood-brain barrier against cerebral ischemia injury in bEnd3 cells.
Cold-inducible RNA-binding protein as a novel target to alleviate blood-brain barrier damage induced by cardiopulmonary bypass.
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Ethyl pyruvate protects against Salmonella intestinal infection in mice through down-regulation of pro-inflammatory factors and inhibition of TLR4/MAPK pathway.
Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells.
ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling.
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Connexin43 dephosphorylation at serine 282 is associated with connexin43-mediated cardiomyocyte apoptosis.
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system.
The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice.
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension.
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
LncRNA CRNDE promotes the epithelial-mesenchymal transition of hepatocellular carcinoma cells via enhancing the Wnt/β-catenin signaling pathway.
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Vanillin protects the blood-milk barrier and inhibits the inflammatory response in LPS-induced mastitis in mice.
Ezrin, a Membrane Cytoskeleton Cross-Linker Protein, as a Marker of Epithelial Damage in Asthma.
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota.
Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats.
The role of sphingosine 1-phosphate receptors on retinal pigment epithelial cells barrier function and angiogenic effects.
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
Oral delivery of a Lactococcus lactis strain secreting bovine lactoferricin-lactoferrampin alleviates the development of acute colitis in mice.
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice.
Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells.
Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy.
Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices.
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Butyrate Protects Mice Against Methionine-Choline-Deficient Diet-Induced Non-alcoholic Steatohepatitis by Improving Gut Barrier Function, Attenuating Inflammation and Reducing Endotoxin Levels.
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Effects of Dietary Serine Supplementation on Intestinal Integrity, Inflammation and Oxidative Status in Early-Weaned Piglets.
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway.
Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases.
Volatile Oil of Amomum villosum Inhibits Nonalcoholic Fatty Liver Disease via the Gut-Liver Axis.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
A novel SWIM domain protein ZSWIM5 inhibits the malignant progression of non-small-cell lung cancer.
ZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling.
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.
Fluoride altered rat's blood testis barrier by affecting the F-actin via IL-1α.
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
Autocrine transforming growth factor-β/activin A-Smad signaling induces hepatic progenitor cells undergoing partial epithelial-mesenchymal transition states.
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD.
Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood-Brain Barrier Permeability During Early Reperfusion in Stroke.
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD(+)-Mediated Epithelial-Mesenchymal Transition.
miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
NIK‑ and IKKβ‑binding protein contributes to gastric cancer chemoresistance by promoting epithelial‑mesenchymal transition through the NF‑κB signaling pathway.
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Effects of chronic noise exposure on the microbiome-gut-brain axis in senescence-accelerated prone mice: implications for Alzheimer's disease.
Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis.
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Tail Vein Infusion of Adipose-Derived Mesenchymal Stem Cell Alleviated Inflammatory Response and Improved Blood Brain Barrier Condition by Suppressing Endoplasmic Reticulum Stress in a Middle Cerebral Artery Occlusion Rat Model.
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Lipopolysaccharide Induces Subacute Cerebral Microhemorrhages with Involvement of Nitric Oxide Synthase in Rats.
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells.
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Paracellular tightness and the functional expression of efflux transporters P-gp and BCRP in bEnd3 cells.
Metformin Protects against LPS-Induced Intestinal Barrier Dysfunction by Activating AMPK Pathway.
Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury.
Potential Orphan Drug Therapy of Intravesical Liposomal Onabotulinumtoxin-A for Ketamine-Induced Cystitis by Mucosal Protection and Anti-inflammation in a Rat Model.
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense.
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Calycosin Suppresses Epithelial Derived Initiative Key Factors and Maintains Epithelial Barrier in Allergic Inflammation via TLR4 Mediated NF-κB Pathway.
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
Role of macrophage migration inhibitory factor (MIF) in the effects of oxidative stress on human retinal pigment epithelial cells.
The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-κB Inhibition.
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Administration of alpha-ketoglutarate improves epithelial restitution under stress injury in early-weaning piglets.
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Small Interfering RNA Targeting Dickkopf-1 Contributes to Neuroprotection After Intracerebral Hemorrhage in Rats.
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
Targeted deletion of Aqp4 promotes the formation of astrocytic gap junctions.
Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.
CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation.
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Phenotype transformation of immortalized NCM460 colon epithelial cell line by TGF-β1 is associated with chromosome instability.
A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells.
SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Knockout of BRD7 results in impaired spermatogenesis and male infertility.
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
Naturally Occurring Stilbenoid TSG Reverses Non-Alcoholic Fatty Liver Diseases via Gut-Liver Axis.
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism.
Par-3 modulates intestinal epithelial barrier function through regulating intracellular trafficking of occludin and myosin light chain phosphorylation.
The multi-targeted tyrosine kinase inhibitor vandetanib plays a bifunctional role in non-small cell lung cancer cells.
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Keratinocyte growth factor pretreatment prevents radiation-induced intestinal damage in a mouse model.
Increased epithelial permeability is the primary cause for bicarbonate loss in inflamed murine colon.
Keratinocyte growth factor improves epithelial structure and function in a mouse model of intestinal ischemia/reperfusion.
Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier.
Soliman Y, Baran G, Mustafaoğlu N
Turkish journal of biology = Turk biyoloji dergisi 2026;50(1):1-16
Turkish journal of biology = Turk biyoloji dergisi 2026;50(1):1-16
Targeting Myeloid FoxO1 Ameliorates Sepsis-induced Intestinal Injury by Modulating Tim4(+) Macrophage Glycolysis.
Ni J, Zhang R, Pu Y, He Y, Hu W, Su L, Hou Y, Dou H
International journal of biological sciences 2026;22(1):239-257
International journal of biological sciences 2026;22(1):239-257
Ulinastatin attenuates capillary leakage and suppresses FoxO1-dependent angiopoietin-2 in sepsis-associated acute lung injury via PI3K pathway.
Lv Y, Meng Y, Rui H, Li T, Zhang J, Liu J, Ma X, Wang J, Yuan Y, Jiang Y, Yan X, Li M, Dong X, Zhang B, Ma L
PloS one 2026;21(4):e0348261
PloS one 2026;21(4):e0348261
Cordycepin Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Inhibiting IL-6/IL-6R-Mediated p38 MAPK and NF-κB Activation Through Adenosine A(2A) Receptor Stimulation.
Liao Y, Wei W, Qin F, Ruan Y, He T, He J, Wang M, Liu T, Chen J
Drug design, development and therapy 2026;20:575035
Drug design, development and therapy 2026;20:575035
Platelet-Rich Plasma Attenuates Knee Osteoarthritis in Rats via Modulation of Gut Microbiota.
Yan D, Li Q, Wang M, Nie Y, Sun X, Na L, Wang H
Drug design, development and therapy 2026;20:574392
Drug design, development and therapy 2026;20:574392
Enterotoxigenic Escherichia coli-induced intestinal epithelial necroptosis drives lamina propria immune cell pyroptosis and mucosal injury in piglets.
Wu X, Liu Y, Wu S, Wei H, Peng J
Frontiers in immunology 2026;17:1778258
Frontiers in immunology 2026;17:1778258
Modified Jiaoqi powder ameliorates ulcerative colitis through gut microbiota-tryptophan metabolism-AhR signaling modulating-ILC2/ILC3 balance.
Jin T, Yi Q, Wang Y, Liu W, Zheng L, An J, Mi H, Zhou L, Liu F, Wang X
Frontiers in microbiology 2026;17:1764082
Frontiers in microbiology 2026;17:1764082
Integrating bioinformatic prediction and the "gut microbiota-inflammation-skin axis" to decipher the mechanisms of quercetin (from Evodia rutaecarpa) in diabetic wound healing.
Huang Z, Liu J, Zheng X, Geng X, Tan J, Ai Y, Li H, Zhou D
Frontiers in immunology 2026;17:1755280
Frontiers in immunology 2026;17:1755280
Akkermansia muciniphila alleviates antibiotic- and LPS-induced oxidative stress via the p38α MAPK-Nrf2 signaling axis.
Ye WY, Feng CX, Su SQ, Wei SM, Mao Y, Chen ZY, Su Y, Shan QW
Frontiers in microbiology 2026;17:1753421
Frontiers in microbiology 2026;17:1753421
2',4'-dihydroxychalcone alleviates inflammatory bowel disease by inhibiting NLRP3 inflammasome and modulating gut microbiota.
Zhang G, Yao Y, Zhang Z, Wang J, Xiao J, Yu H, Huang M, Yao C, Wang Y, Luo H
Frontiers in immunology 2026;17:1751218
Frontiers in immunology 2026;17:1751218
Prim-O-glucosylcimifugin ameliorates DSS-induced ulcerative colitis via suppressing NLRP3 inflammasome activation.
Wang F, Xiong X, Ruan Q, Zhang D, Huang C, Xie T, Cheng L
Frontiers in pharmacology 2026;17:1750305
Frontiers in pharmacology 2026;17:1750305
Lactobacillus rhamnosus confers protection against enteropathogenic bacteria by enhancing mucosal immunity and epithelial barrier function.
Gao X, Zhou J, Yan K, Guan Y, Xiang J, Liu Y, Yu H, Wang J, Li Y, Xu Y
Frontiers in cellular and infection microbiology 2026;16:1769889
Frontiers in cellular and infection microbiology 2026;16:1769889
Rosuvastatin attenuates blood-brain barrier dysfunction after ICH through modulation of CXCL12-associated VEGFR2/p38 MAPK signaling.
Yuan M, Zhou H, Pan H, Xiao Z, Wu H, Wu W
Neuropharmacology 2026 Sep 1;295:110998
Neuropharmacology 2026 Sep 1;295:110998
Gut microbiota mediates the antidepressant-like effects of xiaochaihutang: mechanisms involving inhibition of inflammation and enhancement of barrier function.
Pang J, Ma X, Hong N, Shen Z, Li S, Li X, Wang S, Cong H, Zhang K, Yang J, Wu C
Journal of natural medicines 2026 May;80(3):881-898
Journal of natural medicines 2026 May;80(3):881-898
Puerarin Improves Glucose and Lipid Metabolism in Type 2 Diabetes by Regulating Gut Microbiota Homeostasis and Promoting Adipose Tissue Thermogenesis.
Cheng L, Gan M, Wang H, Song Y, Bai Y, Zhang D
Phytotherapy research : PTR 2026 May;40(5):2397-2416
Phytotherapy research : PTR 2026 May;40(5):2397-2416
Yeast β-glucan alleviates alcohol-related brain injury by restoring gut-brain axis homeostasis.
Li H, Ouyang Z, Li B, Gong D, Bai J, Li J, Zhang S, Liang Z, Long D
International journal of biological macromolecules 2026 May;360:151880
International journal of biological macromolecules 2026 May;360:151880
RIPK1-driven calcium overload and lysosomal-mitochondrial dysfunction induce testicular necroptosis following DEHP exposure.
Ran M, Yi R, Zhang H, Sun X, Qiu T, Li J, Wang N, Yao X, Zhang C, Deng H, Wang S, Yang G
Ecotoxicology and environmental safety 2026 May;316:120163
Ecotoxicology and environmental safety 2026 May;316:120163
Mucin alleviates HFD-induced obesity and MASLD via an Akkermansia muciniphila-associated mucin-Neu5Ac-PPARα signaling axis.
You S, Yu C, Xu Z, Jiao Y, Ao J, Xia X, Li M, Long M, Zhu S, Liu SL, Wang S, Bao H
Pharmacological research 2026 May;227:108174
Pharmacological research 2026 May;227:108174
Bufei Jianspi formula alleviates intestinal epithelial barrier injury by inhibition of calpain 2 in COPD rat.
Wang K, Tao L, Zhang Q, Liu L, Shan B, Zhao P, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158006
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158006
Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol-Induced Intestinal Injury via Microbiota-Dependent and -Independent AHR Activation.
Cui C, Zhang B, Tang J, Hou J, Qiu Y, Gao K, Wang L, Jiang Z, Yang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e22912
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 May;13(25):e22912
Effect of Dietary Electrolyte Balance in Low-Protein Diet on Intestinal Barrier, Mitochondrial Function and Carcass Quality of Growing Pigs.
Hao J, Li L, Lin Q, Tu X, Feng J, Ying Y, Ding L, Li J, Hu C
Journal of animal physiology and animal nutrition 2026 May;110(3):388-397
Journal of animal physiology and animal nutrition 2026 May;110(3):388-397
Multi-omics dissection of lignan diversity and therapeutic potential in Ocimum: Identification of diphyllin as an anti-inflammatory agent targeting TNF-α signaling.
Yang J, Huang T, Huang Y, Yu M, Jiaba W, Su R, Liu L, Guan L
Journal of ethnopharmacology 2026 May 23;363:121412
Journal of ethnopharmacology 2026 May 23;363:121412
Gynostemma pentaphyllum polysaccharides alleviate ulcerative colitis in mice via the Nrf2/ROS/NLRP3 axis and modulation of the gut microbiota.
Qiu M, Yi Q, Luo M, Duan S, Zhang Z, Wu X, Chen T, Ma C, Cui T, Zhang B, Zhang Y, Li J, Guo S, Gao Y, Zhang D
Journal of ethnopharmacology 2026 May 23;363:121373
Journal of ethnopharmacology 2026 May 23;363:121373
Dietary N-acetylneuraminic acid maintains intestinal homeostasis and protects against aging- and inflammation-associated colonic dysfunction.
Li XX, Shi JN, Guan Z, Zeng SY, Luo Y, Gong XX, He SY, Xu KX, Yang Y, Yin H, Wang ZX, Xie H, Shi LJ
International immunopharmacology 2026 May 15;177:116531
International immunopharmacology 2026 May 15;177:116531
Naringin alleviates autoimmune hepatitis in mice via the gut-liver Axis through modulation of microbiota, metabolites, and immune responses.
Zhu Q, Gao M, Yan M, Ma Z, Li X, Yu M, Niu X, Wang J
International immunopharmacology 2026 May 15;177:116498
International immunopharmacology 2026 May 15;177:116498
Inflammation-responsive framework nucleic acids for ulcerative colitis therapy.
Zhang T, Huang J, Chen X, Zhou Y, Chen H, Xiao J, Ma Y, Tong N, Li R, Li W
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114845
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114845
Dual-action nasal spray with mussel protein and xylitol restores epithelial barrier and attenuates type 2 inflammation in allergic rhinitis.
Zhang B, Wang W, Fang P, Wang Y, Xia J, Xu M
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114809
Journal of controlled release : official journal of the Controlled Release Society 2026 May 10;393:114809
Therapeutic potential of Isatidis Radix alkaloids in RSV pneumonia: A focus on AhR-mediated pulmonary barrier repair.
Xu S, Hou X, Xu Y, Wang X, Xu L, He L
Journal of ethnopharmacology 2026 May 10;362:121387
Journal of ethnopharmacology 2026 May 10;362:121387
Fermented grape pomace alleviates Salmonella typhimurium-induced Hepatointestinal inflammation: FXR mediates protection by orchestrating bile acid homeostasis and suppressing the colonic NLRP3 Inflammasome.
Zhang J, Jiang D, Zhang X, Yang Y, Wu Z
Food research international (Ottawa, Ont.) 2026 May 1;231(Pt 2):118797
Food research international (Ottawa, Ont.) 2026 May 1;231(Pt 2):118797
Small extracellular vesicles derived from hair follicle neural crest stem cells enhance perineurial cell proliferation and migration via the TGF-β/SMAD/HAS2 pathway.
Huo Y, Xiao B, Yu H, Xu Y, Zheng J, Huang C, Wang L, Lin H, Xu J, Yang P, Liu F
Neural regeneration research 2026 May 1;21(5):2060-2072
Neural regeneration research 2026 May 1;21(5):2060-2072
Deficiency of exocyst complex component Exoc5 exacerbates the progression of kidney fibrosis.
Lim HJ, Han YK, Noh MR, Park YR, Jang SY, Lipschutz JH, Park KM
Experimental & molecular medicine 2026 Mar;58(3):681-695
Experimental & molecular medicine 2026 Mar;58(3):681-695
c-MAF Transcriptionally Activates Slc40a1 to Repress Ferroptosis in Sepsis-Associated Encephalopathy.
Song W, Shen Q, Zhang H, Bu X, Gao W, Wang W
CNS neuroscience & therapeutics 2026 Mar;32(3):e70820
CNS neuroscience & therapeutics 2026 Mar;32(3):e70820
LC3-positive extracellular vesicles released from tumor cells promote lung metastasis of breast cancer by inducing vascular permeability.
Shen Y, Shen Y, Wang X, Wang F, Liu P, Sun C, Zhang Y, Miao FQ, Zhang J, Wang L
The FEBS journal 2026 Mar;293(5):1478-1494
The FEBS journal 2026 Mar;293(5):1478-1494
Scutellaria baicalensis extract prevents metabolic dysfunction-associated steatotic liver disease by modulating the gut-liver axis in high-fat diet mice.
Ma L, Wang Y, Ren T, Pan L, Li X, Wang S, Li D, Zhang M, Li F, Zheng F, Yue H
Phytochemistry 2026 Mar;243:114720
Phytochemistry 2026 Mar;243:114720
Engineered Bacillus subtilis WB600/ZD reduces post-weaning diarrhea in piglets by modulating gut microbiota and aryl hydrocarbon receptor (AHR) signaling.
Li W, Wang X, Zhang Y, Yang H, Wang X, Meng W, Hu T, Zhang W, Zhu Y, Wang J, Yang G
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Mar;24:46-60
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Mar;24:46-60
Protective impacts of berberine in weaned piglets fed without zinc oxide: Insight of jejunal barrier function, water absorption, and gut microbiota and metabolism.
Sun Y, Liu S, Xu Y, Zhong R, Zhang L, Chen L, Zhang H
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Mar;24:303-315
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Mar;24:303-315
Reversibly unlocking the blood-brain barrier: A study on microtubule dynamics modulation using gold nanoparticle-modified reduced graphene oxide.
Wu J, Cui G, Lin Z, Lin W, Zhang Y, Zhou T, He P, Zhang Y, Yao G
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
A mitochondrial-derived peptide MOTS-c contributes to the protective effect against brain injury associated with LPS-induced sepsis by strengthening the blood-brain barrier's ultrastructure.
Bai Y, Wu H, Wang X, Guo Y, Gong B, Dong B, Yu Y
The International journal of neuroscience 2026 Mar;136(3):329-342
The International journal of neuroscience 2026 Mar;136(3):329-342
Western Diet Inhibits FUT7-Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease.
Zhou Q, Wang X, Ben T, Zhu C, Lin X, Li Y, Zhang X, Chen Y, Xuan Y, Chen H, Liu K, Wu F, Ren Y, Tan G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(13):e09541
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(13):e09541
TRIM27-controlled endothelium-derived exosomes play a central role in podocyte injury in diabetic kidney disease.
Tian Y, Liu Y, Feng X, Wu L, Song W, Zhao T, Liu J, Miao X, Ma H, Jia B, Kang L, Liu Q, Zhang W, Guo H, Yang L, Xu J, Liu S
Cell death discovery 2026 Mar 7;12(1)
Cell death discovery 2026 Mar 7;12(1)
RAB3B regulates vesicle uptake and tight junction integrity in amniotic epithelial cells and is downregulated in premature rupture of membranes.
Su S, Ye Q, Chen F, Tian Q, Gan C, Li Y
Biology of reproduction 2026 Mar 7;
Biology of reproduction 2026 Mar 7;
Nitric Oxide Donor Alleviates Cardiac Arrest Induced Blood Brain Barrier Injury by Inhibiting HMGB1-ATG5 Mediated Endothelial Autophagy.
Duan P, Bi Y, Feng W, Jin Z, Meng Y, Li H, Li X, Luo L, Zhao X, Zhang B
Cellular and molecular neurobiology 2026 Mar 6;46(1)
Cellular and molecular neurobiology 2026 Mar 6;46(1)
Lactobacillus reuteri SKLAN202402ZF inhibited by early-life lincomycin exposure alleviate intestinal damage and inflammation sensitivity.
Zhang S, Tang S, Han H, Xu Y, Liu D, Wang H, Zhong R, Chen L, Zhang H
Microbiome 2026 Mar 6;14(1)
Microbiome 2026 Mar 6;14(1)
Complement protein C1q induces endothelial apoptosis through C1qBP regulation of mitochondrial function in lung endothelial cells in systemic sclerosis.
Yi Z, Liu K, Shabin M
Molecular medicine (Cambridge, Mass.) 2026 Mar 5;32(1)
Molecular medicine (Cambridge, Mass.) 2026 Mar 5;32(1)
Daidzein Confers Prophylactic Protection against Food Allergy by Restoring Immune Regulation, Intestinal Barrier Integrity, and Microbiota-Metabolite Homeostasis.
Yi X, Deng W, Gao K, Ou X, Tang K, Ni Y, Zeng Q, Wu Z, Wu Y, Xie Y, Chen H, Yang A
Journal of agricultural and food chemistry 2026 Mar 4;74(8):7125-7138
Journal of agricultural and food chemistry 2026 Mar 4;74(8):7125-7138
Odevixibat ameliorates high-fat diet-induced MASLD in mice by targeting the gut microbiota-metabolite axis and enhancing gut-liver crosstalk.
Gao X, Dai S, Li J, Wang T, Sun X, Li P
Journal of physiology and biochemistry 2026 Mar 31;82(1)
Journal of physiology and biochemistry 2026 Mar 31;82(1)
Lactiplantibacillus pentosus JWN01 and Lactiplantibacillus plantarum JWN02 attenuate renal fibrosis and pathological autophagy in hyperuricemic nephropathy via gut-kidney axis.
Mo Q, Qin M, Liang H, Wei L, Li Y, Qin Y, Tang L, Liang J, Qian C, Liang Y, Luo S, Wei Y, Kong L, Cheng J
Food research international (Ottawa, Ont.) 2026 Mar 31;228:118376
Food research international (Ottawa, Ont.) 2026 Mar 31;228:118376
ALKBH5 facilitates Srgn stability via m6A demethylation to disrupt blood-testis barrier integrity in the high-fat diet mice.
Du T, Yao L, Wang W, Li Z, Dong J, Zhou Z, Shi C, Ge X, Ma R, Chen L, Xiang Y, He Z, Zheng L, Xu Y, Cao C, Jing J, Ma J, Yao B
Cellular and molecular life sciences : CMLS 2026 Mar 30;83(1)
Cellular and molecular life sciences : CMLS 2026 Mar 30;83(1)
Ketogenic diet alleviates septic lung injury via microbial gut-lung axis.
Wei M, Yi X, Lin Z, Cai J, Chen S, Zhou F, Cai H, Lu X, Tang J, Shi Y, Cui L, Yang L, Jing X, Zeng Y, Wu R, Shu T, Li Y, Yang F, He Y, Zhao Z, Yang Y, Zhu W, Jiang Q, Zhang W, Tan X, Ma Z, Fan X, Ma W, Li S, Shu W, Wei H, Xiang Z, Gilbert JA, Gong S, Wang Z
Cell metabolism 2026 Mar 3;38(3):493-511.e12
Cell metabolism 2026 Mar 3;38(3):493-511.e12
Gut microbiota and metabolomic alterations underlying the therapeutic effects of SQJZ capsules in a rat model of chronic renal failure.
Tan R, Que T, Pan F, Tong N, Wu D, Zhu H, Tong A
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 28;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 28;
Chronic Excessive Exposure to Fluoride Impairs the Intestinal Mucosal Barrier to Cause Inflammatory Response and Microbiome Dysbiosis in Rats.
Zhang JR, Li YW, Chen HX, Luo Y, Liu RM, Wang JB, Liu NN, Xiao JH
Biological trace element research 2026 Mar 28;
Biological trace element research 2026 Mar 28;
Spiky Nanoparticle-Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder.
Zhou Y, Liu Q, Wang L, Sun H, Liu Y, Xiang T, Zhu M, Liu X, Liu T, Cong H, Liao L
Advanced healthcare materials 2026 Mar 27;:e05843
Advanced healthcare materials 2026 Mar 27;:e05843
Protective Effect of Bifidobacterium longum subsp. infantis E4 Exopolysaccharide on Intestinal Barrier, Regulation of Gut Microbiota and Metabolite In Vitro, and Immunosuppressed Mice.
Wang Y, Yue Y, Li J, Wang L, Li B, Yu D
Journal of agricultural and food chemistry 2026 Mar 25;74(11):9235-9252
Journal of agricultural and food chemistry 2026 Mar 25;74(11):9235-9252
β1,4-galactosyltransferase III drives retinoblastoma invasion via activation of integrin-FAK axis.
Tang J, Li J, Wang M, Liu Y, Sun H, Zhang Z, Gao Y, Cheng C, Chen S, Zhang P, Ai S, Su S, Hu Y, Lu R
Cell death & disease 2026 Mar 23;17(1)
Cell death & disease 2026 Mar 23;17(1)
MyD88 inhibitory Peptide-2 (MIP2) improves neurological outcomes and reduces neuroinflammation after intracerebral Hemorrhage-mediated secondary brain injury.
Siddique R, Guo P, Wang Q, Su Q, Qi L, Mazhar M, Aaqib M, Zhang X, Khan S, Yong VW, Xue M
Journal of advanced research 2026 Mar 23;
Journal of advanced research 2026 Mar 23;
Curculigoside attenuates influenza virus-induced acute lung injury by modulating the Keap1/Nrf2 signaling pathway.
Liu T, Chen F, Wu L, Zhang H, Yin P
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 21;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 21;
Exploring the mechanism of Qinlian Yuyang Decoction in the treatment of ulcerative colitis based on multi-omics technology.
Cao YT, Huang X, Yu CL, Wang J, Han X, Wang CW, Luo ZC, Xu WC, Shan JJ, Li YM, Ding K, Zhang Y, Yin AL
Chinese medicine 2026 Mar 20;21(1)
Chinese medicine 2026 Mar 20;21(1)
SGK1 Is Upregulated in Retained Placenta and Mediates Estradiol Effects in Bovine Endometrial Cells.
Wang R, Wei M, Niu W, Chen J, Nan J, Zhang Y, Zhao X, Wang Q
Cells 2026 Mar 20;15(6)
Cells 2026 Mar 20;15(6)
Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy.
Zink A, Dai DF, Wittich A, Henke MT, Pedrotti G, Heiduschka S, Santamaria G, Pentimalli TM, Brueser C, Notopoulou S, Umar AR, Zhaivoron A, Petersilie L, Jerred C, Bergmans J, Neu LA, Schumacher F, Keller-Findeisen J, Rybak-Wolf A, Stach D, Reinshagen J, Haferkamp U, Krieg K, Zaliani A, Euro L, Di Donfrancesco A, Santanatoglia C, Cappellozza E, Suarez Cubero M, Pavez-Giani M, Bakumenko O, Meierhofer D, Foley A, Morales-Gonzalez S, Tolle I, Herebian D, Bonesso D, Cecchetto G, Wong SN, Moresco M, Maresca A, Decimo I, De Sanctis F, Adamo A, Adjobo-Hermans MJW, Duchi R, Barandalla M, Scaglia M, Perota A, Galli C, Kleuser B, Cyganek L, Mühlhausen C, Schlotawa L, Tiranti V, Mayatepek E, Szabo I, La Morgia C, Klopstock T, Carelli V, Distelmaier F, Rossi A, Rajewsky N, Ullah G, Jakobs S, Rose CR, Petrakis S, Edenhofer F, Koopman WJH, Lisowski P, Suomalainen A, Brunetti D, Del Sol A, Bottani E, Pless O, Schuelke M, Prigione A
Cell 2026 Mar 19;189(6):1656-1679.e42
Cell 2026 Mar 19;189(6):1656-1679.e42
Quercetin Ameliorates Comorbid Insomnia in Diarrhea-Predominant Irritable Bowel Syndrome via the PI3K/AKT/NF-κB Signaling Pathway.
Liu G, Kong X, Zhao Y, Cai N, Wang H, Sun H, Zhao P
Biomedicines 2026 Mar 17;14(3)
Biomedicines 2026 Mar 17;14(3)
Transcriptomics and metabolomics reveal functional nanoplastics-induced male reproductive damage and resveratrol antagonistic effects.
Zhang F, Zhang N, Wang C, Zhang L, Yang Y, Jia Y, Huang X, Li M, Tang J, Xu L
Journal of nanobiotechnology 2026 Mar 16;24(1)
Journal of nanobiotechnology 2026 Mar 16;24(1)
tLyP-1 peptide-modified MnO₂ co-delivering si-SLC16A1 and temozolomide synergistically suppresses glioblastoma via hypoxia modulation and metabolic stress.
Zhao H, Meng L, Du P, Chen Y, Gong M, Zan B, Chen J, Zeng M, Liao Y
Journal of nanobiotechnology 2026 Mar 16;
Journal of nanobiotechnology 2026 Mar 16;
Glycine alleviates the intestinal epithelial barrier damage induced by imidacloprid via promoting metabolic detoxification.
Cheng W, Wang Y, Li Y, Zhao G
Ecotoxicology and environmental safety 2026 Mar 15;313:120002
Ecotoxicology and environmental safety 2026 Mar 15;313:120002
Renal Tubule-Specific Deletion of Nephrocystin 3 (Nphp3) Causes Infantile Nephronophthisis-like Phenotypes in Mice.
Du X, Wang C, Fang Y, Wang G, Zhai Y, Shen Q, Tang X, Xu H
International journal of molecular sciences 2026 Mar 15;27(6)
International journal of molecular sciences 2026 Mar 15;27(6)
A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation-Dependent Cell Adhesion.
Zhong J, Lu J, Li H, Zhong J, Luo X, Hu Y, Wang X, Wang P, Zhang Y, Wang Z, Lai Q, Chen Z, Mi W, San-To WT, Li W, Tan S, Cheng Q, Li R, Nie Y, Liu S, Huang B, Han Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 15;:e23872
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 15;:e23872
Synergistic disruption of the blood-brain barrier in tree shrews by Methamphetamine and HIV-1 Tat via TRPM2-Mediated astrocyte inflammation.
Teng HX, Huang J, Miao L, Yang X, Xu LS, Zhao YJ, Li J, Zeng XF
Brain, behavior, and immunity 2026 Mar 14;136:106538
Brain, behavior, and immunity 2026 Mar 14;136:106538
Identification of Ellagic Acid as a Natural GPR35 Agonist for Ulcerative Colitis Therapy.
Liu H, Yang L, Ma X, Wang G, Wang D, Liu X, Li Z, Guo D
Biomolecules 2026 Mar 13;16(3)
Biomolecules 2026 Mar 13;16(3)
Glibenclamide Attenuates Brain Edema After Intracerebral Hemorrhage Through Preservation of Blood-Brain Barrier Integrity and Glymphatic Function.
Du C, Wu Y, Geng Y, Ali A, Li Z, Liu Z, Ma C
Neurochemical research 2026 Mar 10;51(2)
Neurochemical research 2026 Mar 10;51(2)
Dietary semen cuscuta improves laying performance by stabilizing mitochondria-associated membranes (MAMs) and inhibiting granulosa cell apoptosis in laying hens.
Si C, Chen Y, Liu L, Liu S, Zhang Z, Guo L, Zhao M, Chen Y, Shi Y, Shi W, Ma S
Poultry science 2026 Mar 10;105(6):106749
Poultry science 2026 Mar 10;105(6):106749
Shenqi funeng xingnao prescription regulated the TNF/NOD‒like receptor signaling pathway and brain-gut axis dysfunction caused by exercise-induced fatigue.
Xu D, Zhang W, Tao XR, Gao K, Zhao MN, Wang JW
Journal of ethnopharmacology 2026 Mar 1;358:121035
Journal of ethnopharmacology 2026 Mar 1;358:121035
High fluoride exposure disrupts gut microbiota and induces intestinal barrier damage via RhoA/ROCK-mediated cytoskeletal remodeling.
Wang D, Xin J, Lai C, Sun N, Yang Y, He Y, Duan L, Luo J, He Y, Zhang Y, Zhang Y, Wang H, Zeng D, Bai Y, Ni X
Ecotoxicology and environmental safety 2026 Mar 1;312:119898
Ecotoxicology and environmental safety 2026 Mar 1;312:119898
The engineered probiotic strain Lactococcus lactis MG1363-pMG36e-GLP-1 regulates microglial polarization and gut dysbiosis in a transgenic mouse model of Parkinson's disease.
Yue M, Chen T, Chen W, Wei J, Liao B, Zhang J, Li F, Hong D, Fang X
Neural regeneration research 2026 Mar 1;21(3):1211-1221
Neural regeneration research 2026 Mar 1;21(3):1211-1221
Berberine alleviates soybean meal-induced enteritis in hybrid yellow catfish (Pelteobagrus fulvidraco ♀ × Pelteobagrus vachelli ♂) by regulating intestinal microbiota and tryptophan metabolism.
Zhang Z, Hong J, Zhang M, Liu Y, Wu C, Huang X, Dong P, Yang Z, Guo G, Xie S, Wu G, Li G, Li M, Yu G, Liu B
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Jun;25:360-374
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2026 Jun;25:360-374
Limbal organoids and bioengineering sheets based on niche microphysiological systems and bioprinting for corneal injury repair in rabbits.
Chen S, Cao J, Ye X, Xie F, Wang W, Liang Y, Yang T, Xie M, Liang L, Su C, Zhang J, Cui Z, Chen J
Acta biomaterialia 2026 Jun;216:137-155
Acta biomaterialia 2026 Jun;216:137-155
The Scutellaria baicalensis-Coptis chinensis herb pair ameliorates ulcerative colitis via integrated modulation of the aryl hydrocarbon receptor/NLRP3 inflammasome axis with tryptophan metabolites.
Fang D, Sheng X, Li X, Tan B, Zhang J, Ding K, Kang A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158164
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158164
Senkyunolide I attenuates radiation-induced cognitive dysfunction by restoring PINK1-Parkin-mediated mitophagy and redox homeostasis.
Yan T, Guo S, Zhang S, Wang Q, Zhang Z, Zhao W, Li X, Lai N, Jiang W, Xu Y, Yang L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158136
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158136
Rhubarb ameliorates ischemic stroke-induced tryptophan-kynurenine metabolic reprogramming and neuroinflammation via modulation of the IDO-1/TREM-1 pathway.
Liu X, Wang X, Wang Y, Zhu H, Xiang Q, Li Q, Wang X, Xu W, Jiang M, Wang W, Gao J, Wang T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158133
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158133
Modified Ganlu Xiaodu decoction attenuates airway barrier injury in Mycoplasma pneumoniae pneumonia by inhibiting ZBP1-mediated PANoptosis.
Zhang Y, Feng J, Diao J, Gou J, Liang Y, Wang X, Song Z, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158112
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158112
Huanglian muxiang decoction alleviates FTH-mediated ferroptosis in colitis by inhibiting the PI3K-AKT pathway.
Wang Y, Li T, Wang Y, Li J, Song L, Fu Y, Li W, Li L, Qiu Y, Yan J, Yang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158083
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158083
Dehydroandrographolide succinate alleviates ulcerative colitis via regulating RAB9A/NF-κB axis-mediated macrophage polarization and remodeling the gut microbiota.
Liu J, Mai Y, Xie Y, Zhou X, Ye Y, Jiang D, He L, Ye Z, Li D, Xia C, Su J, Huang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158039
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158039
Synergistic tissue destruction by Staphylococcus aureus and Staphylococcus epidermidis in a 3D human skin biofilm equivalent.
Nuwayhid R, Ngoc-Huyen N, Lippmann N, Dietze N, Kursawe L, Kikhney J, Moter A, Kobbe P, Siemers F, Roth A, Langer S, Pempe C, Kurow O
Biofilm 2026 Jun;11:100361
Biofilm 2026 Jun;11:100361
EDIL3 regulates caveolin-1-dependent endothelial permeability in subchondral bone during osteoarthritis.
Ma Y, Feng K, Tian K, He X, Yan J, Wang R, Ma P, Tang Z, Zhu G, Yang Y, Sun R, Su Y, Xue D, Chen Z, Lin X, Jin Q
International immunopharmacology 2026 Jun 15;179:116637
International immunopharmacology 2026 Jun 15;179:116637
Swertia chirayita ameliorates MAFLD by improving intestinal microenvironment and hepatic lipogenesis.
Gou X, Shen Y, Liu F, Wang Y, Zong Y, Qu D, Ren Zeng C, Nhamdriel T, Kuang T, Fan G
Journal of ethnopharmacology 2026 Jun 12;364:121471
Journal of ethnopharmacology 2026 Jun 12;364:121471
Immune-epithelial dual-targeting bilirubin nanoparticles for acute lung injury.
Tang Y, Xu Y, Ye J, Han Y, Zhang M, Sun Y, Kang Y, Zhu S, Cai L, Wu R, Gong W, Yao Q, Duan B, Kou L, Chen R, Zhang H
Journal of controlled release : official journal of the Controlled Release Society 2026 Jun 10;394:114852
Journal of controlled release : official journal of the Controlled Release Society 2026 Jun 10;394:114852
Beneficial effects of electro-acupuncture treatment in photothrombotic ischemia model rats by remodeling neurovascular unit.
Li Z, Xiao Y, Zhou S, Lam M, Ding Y, Lin R, Yang M, Liang S, Tao J
Brain research bulletin 2026 Jun 1;239:111858
Brain research bulletin 2026 Jun 1;239:111858
Zanthoxylum bungeanum essential oil alleviates DSS-induced ulcerative colitis in mice by modulating gut microbiota-dependent AhR/Nrf2 signaling.
Sun L, Xu B, Liang Y, Tao Y, Wei C, Du W, Chen P, Wang L, Yang X, Chen X
Food research international (Ottawa, Ont.) 2026 Jun 1;233(Pt 1):118986
Food research international (Ottawa, Ont.) 2026 Jun 1;233(Pt 1):118986
The immunomodulatory metabolite butyrate ameliorates renal fibrosis by restoring gut barrier integrity and suppressing the TGF-β1/Smad3 pathway.
Liu G, Sun Q, Yan Q, Tang F, Lai LS, De Li X
International immunopharmacology 2026 Jun 1;178:116557
International immunopharmacology 2026 Jun 1;178:116557
Spatiotemporally engineered microneedle for microenvironment remodeling propels mucosal regeneration after tracheal mucosal injury.
Wang P, Ci Z, Zhao E, Hu C, Chen B, Gao E, Bo Q, Bian C, Li Y, Song X, Zhou G, Xu T, Duan L
Bioactive materials 2026 Jul;61:272-289
Bioactive materials 2026 Jul;61:272-289
Inhibition of endothelial ALOX12 mitigates cerebral ischemia-reperfusion injury by suppressing 12-HETE.
Wang T, Zhang J, Lu G, Han D, Mi T, Ma X, Wang L, He Z, Niu J
Free radical biology & medicine 2026 Jul;250:134-152
Free radical biology & medicine 2026 Jul;250:134-152
Shaoyao Gancao Decoction alleviates ulcerative colitis-associated secondary liver injury by inhibiting the phosphorylation of pyruvate dehydrogenase in macrophages.
Tang F, Tang Y, Li L, Zhou F, Sun C, Ouyang B, Huang D, Li M, He W, Pei G, Tan Y
Journal of ethnopharmacology 2026 Jul 15;366:121652
Journal of ethnopharmacology 2026 Jul 15;366:121652
Dual benefits of Xiao Chai Hu Tang and its active compounds in CPT-11 therapy: intestinal protection via barrier restoration and anti-inflammation combined with enhanced tumor apoptosis.
Zhang Y, Cao X, Hou Z, Liu Z, Liu S
Journal of ethnopharmacology 2026 Jul 15;366:121621
Journal of ethnopharmacology 2026 Jul 15;366:121621
Methyl 3-chloroasterric acid exerted anti-neuroinflammatory and antidepressant effects through the downregulation of P2Y1R.
Zhang Y, Sun M, Zhang Z, Jia Y, Xiao H, Xu X, Pan X, Li Z
International immunopharmacology 2026 Jul 15;181:116689
International immunopharmacology 2026 Jul 15;181:116689
COXFA4L3 enhances mitochondrial complex IV function to boost ATP synthesis and drive sperm motility.
Tokito R, Oishi K, Sugiyama T, Fujisawa Y, Kuba F, Yoshida K, Yoshida K, Yoshida M, Tanaka Y, Amo T, Yamaguchi N, Akiyama T, Imai Y, Yoshimi K, Koide T, Kurihara Y
Mitochondrion 2026 Jan;86:102082
Mitochondrion 2026 Jan;86:102082
Metformin attenuates colitis via blocking STAT3 acetylation by reducing acetyl-CoA production.
Li X, Xiang Z, Wang X, He H, Xu M, Tan C, Wu X, Zhang J, Dong W
Journal of advanced research 2026 Jan;79:393-407
Journal of advanced research 2026 Jan;79:393-407
Targeting PTPN13 with 11-amino-acid peptides of C-terminal APC prevents immune evasion of colorectal cancer.
Ma WH, Li WY, Chen T, Jing L, Chen YH, Li K, Xu ZL, Shen RF, He Y, Mou T, Luo TY, Sun X, Wu ZK, Wang LJ, Liu HJ, Qiu X, Gao Y, Bai X, Wang W, Wu D, Li G, Zhou WJ
Cell research 2026 Jan;36(1):72-93
Cell research 2026 Jan;36(1):72-93
Bacterial cellulose repairs asthmatic epithelial injury by reprogramming CDS1-mediated phosphatidylinositol metabolism to inhibit PI3K/AKT signaling.
Yu Q, Huang L, Wu Z, Zhuo J, Huang H, Cheng Y, Hu M, Wang Q, Liu D, Jiang X, Zhang J, Cai S, Dong H
International journal of biological macromolecules 2026 Jan;338(Pt 2):149695
International journal of biological macromolecules 2026 Jan;338(Pt 2):149695
Selective peptide-guided transcytosis enhances extracellular vesicle-mediated siRNA delivery across the blood-brain barrier.
Fang J, Zhang L, Wang Y, Chen M, He Y, Zhang CY, Zhang Y, Jiang X, Li J
The Journal of biological chemistry 2026 Jan;302(1):110942
The Journal of biological chemistry 2026 Jan;302(1):110942
PFOS-induced black liver and hepatic aging in mice: A new paradigm in environmental hepatotoxicology.
Stevenson CK, Wang J, Du C
Environment international 2026 Jan;207:109999
Environment international 2026 Jan;207:109999
Increased glucose transporter 1 contributes to epithelial barrier dysfunction in allergic rhinitis.
Xia C, Zhu K, Yu C, Chen J, Gao T, Zhang Y
The World Allergy Organization journal 2026 Jan;19(1):101158
The World Allergy Organization journal 2026 Jan;19(1):101158
Unraveling the active ingredients and molecular mechanisms of Qinghua Changyan granule against irritable bowel syndrome with diarrhea: Effects on gut microbiota and glutamine transport via an integrative approach combining UHPLC-MS/MS and experimental verification.
Yang J, Wang Y, Wang S, Liu Z, Chen X, Jia R, Wang J, Wang F, Yang Q, Tang L, Miao W
Fitoterapia 2026 Jan;188:106960
Fitoterapia 2026 Jan;188:106960
Limosilactobacillus reuteri DSM17938 Attenuates Neuroinflammatory Responses After Spinal Cord Injury by Modulating Tryptophan Metabolism.
Cen Q, Cui Y, Feng J, Zhu L, Wei J, Wang L, Chang C, Pang R, Wang J, Zhang A
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
Probiotics and antimicrobial proteins 2026 Jan;18(1):583-601
Targeted demethylation of the BRD7 promoter based on CRISPR/dCas9 system inhibits the malignant progression of nasopharyngeal carcinoma.
Wei J, Duan Y, Xue C, Zheng L, Wei Q, Wu Z, Xin H, Zeng T, Deng H, Fan S, Xiong W, Zeng Z, Li M, Zhou M
Clinical and translational medicine 2026 Jan;16(1):e70583
Clinical and translational medicine 2026 Jan;16(1):e70583
FABP4-mediated lipid droplet accumulation drives epithelial-mesenchymal transition and aggravates alveolar epithelial barrier disruption.
Shen Z, Qi Y, Chu M, Wu M, Feng C, Li X, Liu Z, Si L, Wang Y, Zhang J, Lu X, Lu P
Clinical and translational medicine 2026 Jan;16(1):e70563
Clinical and translational medicine 2026 Jan;16(1):e70563
Inhalable songorine-integrated lipid nanomedicine for targeted ARDS therapy via repairing endothelial barrier and inactivating NLRP3 inflammasome.
Wang H, Sun ZC, Dai C, Liao R, Lin R, Wang L, Fu W, Zhang R, Zheng D, Zhang Z, Wu J, Liu Y
Acta pharmaceutica Sinica. B 2026 Jan;16(1):596-615
Acta pharmaceutica Sinica. B 2026 Jan;16(1):596-615
Elucidating the mechanism of traditional Chinese medicine formula (Yifei-sanjie Pill) in alleviating the chemobrain based on network pharmacology and experimental verification.
Wu Y, Wang H, Liang Z, Cui J, Liu S, Chen Y, Pi D, Ouyang M
Journal of traditional and complementary medicine 2026 Jan;16(1):17-30
Journal of traditional and complementary medicine 2026 Jan;16(1):17-30
Nutritional Modulation of Melatonin-SIRT1 Signaling by Octanoic Acid-Rich Enteral Nutrition Protects Against Radiation-Induced Intestinal Injury.
Zhou C, Li X, Xing C, Cao C
Food science & nutrition 2026 Jan;14(1):e71465
Food science & nutrition 2026 Jan;14(1):e71465
Lactobacillus Salivarius-Derived Indole-3-Acetic Acid Promotes AHR-PARP1 Axis-Mediated DNA Repair to Mitigate Intestinal Aging.
Cao Z, Zhang C, Lei H, Lin W, Yu W, Gao X, He Y, Li X, Xiang Q, Zhang Z, Luo W, Patterson AD, Zhang L, Chen G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e15794
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e15794
Inhibiting Liver-Derived C3 Protein Rescues Anesthesia/Surgery-Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis.
Wu Q, Cong P, Li Z, Zhang Y, Wu H, Zhang Q, Li Y, Tian L, Miao Q, Zheng Y, Zhang H, Chen Q, Feng E, Li X, Chen Z, Wang DX, Huang X, Xiong L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e02034
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e02034
Scutellarein from Erigeron breviscapus Inhibits Apoptosis-Mediated Epithelial Barrier Disruption and Alleviates Cigarette Smoke-Induced Lung Injury.
Xi C, Fu H, Qin X, Wang Y, Ren K, Song M, Liang H, Zhao F, Cao Z
Pharmaceuticals (Basel, Switzerland) 2026 Jan 8;19(1)
Pharmaceuticals (Basel, Switzerland) 2026 Jan 8;19(1)
Ptbp2 Alleviates Neuroinflammation and Blood-brain Barrier Disruption via Modulating Microglial Polarization in Ischemic Stroke.
Xu W, Li L, Zhou M, Zhang C, Zhang X
Molecular neurobiology 2026 Jan 30;63(1):408
Molecular neurobiology 2026 Jan 30;63(1):408
Chaihu Longgu Muli Decoction attenuates chronic stress-induced endothelial dysfunction and potentiates chemotherapy in breast cancer by inhibiting cAMP/PKA/CREB1 mediated glycolysis.
Li Z, Wang Z, Yang W, Li Y, Li Y, Xu E
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120670
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120670
Comparative studies on the components and anti-ulcerative colitis effects of raw and carbonized Linderae Radix.
Zheng X, Li K, Hu J, Zhang Z, Pan J, Xia A, Ge Z, Wang J, Lou Z
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120629
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120629
Chrysophanein of Rhubarb rescues ILC3-Derived IL-22 by blocking CCDC25/ILK/HIF-1α for mucosal healing in ulcerative colitis mice.
Xu B, Cao S, Li C, Zhao M, Wang Q, Xie X, Chen H, Xu R, Yi Q, Ke X, Zhu Y, Zhou L, Luo X
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120628
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120628
A Feline Milk-Drived Pediococcus acidilactici M22 Alleviates Escherichia coli O157:H7 Infection Through Anti-Adhesion, Anti-Inflammation, and Microbiota Modulation.
Gong X, Wang X, Huang H, Han J, Wang Z, Wen M
Microorganisms 2026 Jan 30;14(2)
Microorganisms 2026 Jan 30;14(2)
A 3D-Printed Pump-Free Multi-Organ-on-a-Chip Platform for Modeling the Intestine-Liver-Muscle Axis.
Kado Abdalkader R, Fujita T
Micromachines 2026 Jan 28;17(2)
Micromachines 2026 Jan 28;17(2)
Gut metabolite indole-3-acetic acid aggravates neuropsychiatric lupus via the AHR/STAT3 pathway in microglia.
Feng Y, Zheng L, Tang W, Wang P, Lai Y, Qin J, Zhou C, Zhang X, Yang M, Jie L, Yu G, Ren H, Huang Q
Communications biology 2026 Jan 23;9(1):281
Communications biology 2026 Jan 23;9(1):281
Danthron Attenuates Intestinal Inflammation by Modulating Oxidative Stress via the EGFR-PI3K-AKT and Nrf2-HO-1 Pathways.
Ni C, Liu H, Jiang H, Lin Z, Wu K, Wang R, Yang H, Li W, Fan C, Zhao Y
Antioxidants (Basel, Switzerland) 2026 Jan 23;15(2)
Antioxidants (Basel, Switzerland) 2026 Jan 23;15(2)
Brain capillary endothelial-like cells show altered barrier functionality and reduced transport of amyloid β in late-onset Alzheimer disease.
Hartmann C, Haferkamp U, Appelt-Menzel A, Barenberg J, Brachner A, Ehrhard T, Feldhaus J, Gerhartl A, Hollemann T, Kulka LAM, Leckzik S, Leu J, Woo MS, Friese MA, Initiative ADN, Metzger M, Neuhaus W, Oerter S, Olzscha H, Pich A, Riemann D, Pless O, Rujescu D, Jung M
Fluids and barriers of the CNS 2026 Jan 22;23(1):11
Fluids and barriers of the CNS 2026 Jan 22;23(1):11
Strategically isolated bacteriophages targeting ETEC K88 (F4) alleviate post-weaning diarrhea in piglets via modulation of gut microbiota and inflammatory responses.
Chen Y, Ding M, Chen X, Zou T, Liu Y, Chen J, You J
Journal of animal science and biotechnology 2026 Jan 18;17(1):11
Journal of animal science and biotechnology 2026 Jan 18;17(1):11
Calcium carbonate supplementation exacerbated gut microenvironment disruption in senile osteoporosis mice.
Chen J, Liu J, Xu M, Fu Q, Si H
iScience 2026 Jan 16;29(1):114530
iScience 2026 Jan 16;29(1):114530
Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers.
Cheng J, Wu P, Li C, Han Y, Sun M, Dou Y, Chen S, Zhang J
Science advances 2026 Jan 16;12(3):eaea2989
Science advances 2026 Jan 16;12(3):eaea2989
Luteolin Enhances Endothelial Barrier Function and Attenuates Myocardial Ischemia-Reperfusion Injury via FOXP1-NLRP3 Pathway.
Xie H, Zhong X, Li N, Zhou M, Zhang M, Yang X, Wang H, Yan Y, Gao P, Liu T, Wang Q, Guo D
International journal of molecular sciences 2026 Jan 15;27(2)
International journal of molecular sciences 2026 Jan 15;27(2)
Natural Dietary Flavonoid Apigenin Mitigates Ulcerative Colitis via Modulating the AMPK/NF-κB/NLRP3 Signaling Axis.
Zhou M, Mao X, Zou LE, Yang Y, Zhao W, Yang Y, Sun S, Mao Z, Li P, Qi G
Journal of agricultural and food chemistry 2026 Jan 14;74(1):983-997
Journal of agricultural and food chemistry 2026 Jan 14;74(1):983-997
Fecal microbiota transplantation from healthy piglets ameliorates intestinal inflammation in mice by modulating recipient metabolism.
Yang Y, Wang Y, Li J, Gao Y, Wu Z, Tan X, Feng S, Cheng W, Zhang H, Gan Q, Wei H, Li Q
BMC microbiology 2026 Jan 12;26(1):147
BMC microbiology 2026 Jan 12;26(1):147
Clostridium perfringens Type A Isolated from Intestinal Contents of Alpaca.
Ren H, Jia Q, Gao S, Yang H, Zhang S, Fan R
Microorganisms 2026 Jan 12;14(1)
Microorganisms 2026 Jan 12;14(1)
Flash nano-encapsulation of probiotics: Bolstering environmental resistance and intestinal colonization to prevent necrotizing enterocolitis.
Huang Y, Niu W, He Y, Zhuang X, Qu Z, Lan X, Zheng C, Lin Z, Xin F, Li D, Huang Y, Lin Y
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114481
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114481
Effects of Modified Xuanbai Chengqi Decoction against secondary Streptococcus pneumoniae infection following influenza virus infection: A multi-omics analysis.
Yang J, Shi J, Xu W, Mu J, Chang Y, Zhang X, Wang X
Journal of ethnopharmacology 2026 Jan 10;354:120458
Journal of ethnopharmacology 2026 Jan 10;354:120458
Investigating the Protective Mechanisms of Ginseng-Natto Composite Fermentation Products in Alzheimer's Disease: A Gut Microbiota and Metabolomic Approach.
Li Z, Wang H, Yuan H, Zhang Y, Yang B, Ji G, Yao Z, Kuang M, Wu X, Wang S, Wang H
Pharmaceuticals (Basel, Switzerland) 2026 Jan 10;19(1)
Pharmaceuticals (Basel, Switzerland) 2026 Jan 10;19(1)
Activation of Intestinal Mast Cells Contributes to Gut Damage After Cardiac Arrest in Mice.
Dang L, Rehman AU, Zhang J, Zhang R, Yu X, Sheng H, Karhausen J, Yang W
Shock (Augusta, Ga.) 2026 Jan 1;65(1):85-92
Shock (Augusta, Ga.) 2026 Jan 1;65(1):85-92
Inulin with different degrees of polymerization adopts different strategies to mitigate radiation-induced intestinal injury: focus on intestinal epithelial or T cell homeostasis.
Ji K, Jia X, Lu X, Zhang D, Du L, Wang J, Wang Y, Song H, He N, Xu C, Gu Y, Yang M, Dong J, Yuan Y, Li J, Zhang M, Liu Q
Carbohydrate polymers 2026 Jan 1;371:124490
Carbohydrate polymers 2026 Jan 1;371:124490
Chitosan alleviates symptoms of Parkinson's disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood-brain barrier.
Wang Y, Chen R, Shi G, Huang X, Li K, Wang R, Cao X, Yang Z, Zhao N, Yan J
Neural regeneration research 2026 Jan 1;21(1):377-391
Neural regeneration research 2026 Jan 1;21(1):377-391
HPGDS promotes tubular injury and interstitial inflammation in diabetic nephropathy by activating canonical pyroptosis pathway.
Huang Y, Li S, Li W, Zhang T, Lu Z, Li C, Zhu X, Yang T, Lu Q, Dong B, Wang J, Zhou W, Yan M
International immunopharmacology 2026 Jan 1;168(Pt 2):115911
International immunopharmacology 2026 Jan 1;168(Pt 2):115911
Obacunone inhibits RIPK1/RIPK3/MLKL-mediated necroptosis by suppressing mitochondrial ROS and MIF signaling in intestinal ischemia-reperfusion injury.
Li XY, Xie JY, Yin YT, Weng XG, Huang ZY, Wang LS, Ding K, Chen R, Meng QT
International immunopharmacology 2026 Jan 1;168(Pt 2):115901
International immunopharmacology 2026 Jan 1;168(Pt 2):115901
Combined metabolomics and gut microbiota analysis reveals the protective effects of α-monoglucosyl rutin against cyclophosphamide-induced intestinal injury.
Tian J, Xiao F, Xu Y, Chen Y, He C, Jiang S, Tang Y
International immunopharmacology 2026 Jan 1;168(Pt 2):115887
International immunopharmacology 2026 Jan 1;168(Pt 2):115887
Ganoderic Acids Alleviate Neuroinflammation by Targeting Myeloid Differentiation Factor 2 for Ischemic Stroke Therapy.
Ma A, Zhu Y, Ying Y, Wang S, Zhang J, Feng N, Quan Y, Shao G, Liu D, Zhang S, Geng X, Zhou H, Li M, Lin D, Wang L, Liang G, Li S, Yang B
Exploration (Beijing, China) 2026 Feb;6(1):20240147
Exploration (Beijing, China) 2026 Feb;6(1):20240147
AURKA modulates tight junction functionality to influence the proliferation and metastasis of lung adenocarcinoma.
Mi Y, Mao J, Li X, Wang Z, Zuo X, Chang Z, Wang R, Wang L, Wang L
Molecular and cellular biochemistry 2026 Feb;481(2):825-840
Molecular and cellular biochemistry 2026 Feb;481(2):825-840
Improving glucose tolerance in obese rats: the role of Jinlida granules ( ) in gut microbiota modulation.
Dongqi LI, Tongxing W, Zixuan W, Yihui Y, Jie LI, Jiaojiao GU, Cuiru LI, Aili W, Lingling S, Yongjie M, Zeyu Z, Yunlong H, Huailin G
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2026 Feb;46(1):62-72
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2026 Feb;46(1):62-72
Repairing effect of total glucosides of Paeonia on deoxynivalenol-induced enterohepatic axis damage in weaned piglets.
Guo S, Li H, Peng B, Lv Z, Duan Y, Niu J, Guo Y, Wang Z, Zhang W
Ecotoxicology and environmental safety 2026 Feb;311:119876
Ecotoxicology and environmental safety 2026 Feb;311:119876
Bacteroides acidifaciens alleviates high-fat diet-induced obesity-related osteoporosis by regulating gut microbiota and bile acid metabolism via the gut-bone axis.
Zheng C, Xie J, Tang F, Wang Z, Liu L, Pi Y, Zhong Y, He Z, Liu T, Zheng J, Luo J
Microbiological research 2026 Feb;303:128393
Microbiological research 2026 Feb;303:128393
Meningitic Escherichia coli disrupts the blood-brain barrier through pyroptosis and tight junction degradation and NLRP6 deficiency aggravates infection outcomes.
Jia K, Du Y, Cao X, Shen X, Ran J, Lu Y, Peng L, Li Z, Fang R
Microbiological research 2026 Feb;303:128388
Microbiological research 2026 Feb;303:128388
Resveratrol Inhibits Pancreatic Cancer Progression by Regulating CDC42 Succinylation and Disrupting the Extracellular Matrix.
Ding M, Wang Q
Rejuvenation research 2026 Feb;29(1):18-28
Rejuvenation research 2026 Feb;29(1):18-28
Dynamin-Related Protein 1-Dependent Disruption of Mitochondrial Homeostasis Drives Blue Light-Induced Epithelial-Mesenchymal Transition in Retinal Aging.
Li ZY, Yang D, Huang Y, Li Y, Zhao T, Xu Y
Aging cell 2026 Feb;25(2):e70416
Aging cell 2026 Feb;25(2):e70416
Engineered probiotics for the in vivo mitigation of waterborne uranium toxicity and bioaccumulation.
Li H, Zhang F, Wang C, Cui Z, Liu Y, Song Z, Yuan L, Chen X, Wu Y, Wu W, Tian L
Environment international 2026 Feb;208:110127
Environment international 2026 Feb;208:110127
Oral colon-targeted paeonol emulsion for ameliorating ulcerative colitis based on charge adsorption.
Zhang L, Xiong X, Lu W, Li J, Zhang R, Cai Z, Lv H, Zhang Z, Ju J, Yang Y
Drug delivery and translational research 2026 Feb;16(2):675-692
Drug delivery and translational research 2026 Feb;16(2):675-692
MiR-21 modulates P.g-LPS induced apoptosis and inflammatory response in HUVECs via NF-κB/iNOS/NO pathway by targeting PDCD4.
Ren J, Zou H, Sun S, Chen S, He R, Zhou Q, Tao J, Yang J
Non-coding RNA research 2026 Feb;16:144-155
Non-coding RNA research 2026 Feb;16:144-155
Acute sleep deprivation reduces thermotolerance and exacerbates heat stroke via disruption of intestinal barrier integrity in rats.
Li L, Xie Y, Gong Y, Chen J, Wang Y, Pei Y, Zhou J, You J, Cao Y, Song M, Sun H, Ma W, Wang M, Ma J, Chen J, Chang W, Song Q, Wang Y, Wang Q, Xu S
Sleep medicine 2026 Feb;138:108699
Sleep medicine 2026 Feb;138:108699
Brd4 BD1 Domain Antagonism of MS436 Preserves Blood-Brain Barrier Integrity via Rnf43/β-Catenin Signaling Pathway.
Li C, Zhang X, Xia J, Liu S, Du Y, Li S, Zhang S, Zhang Y, Ji F, Jiao J, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e15584
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(7):e15584
Mettl3-Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS.
Zhu F, Li H, Li X, Du C, Wang T, Zhou X, Xie X, Shao Y, Huang Y, Hu Y, Guo X, Zhu B, Yu S, Zhang X, Zhao B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e01242
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e01242
Uropathogenic Escherichia coli invade luminal prostate cells via FimH-PPAP receptor binding.
Guedes M, Peters S, Joshi A, Dorn S, Rieger J, Klapproth K, Beste T, Leipold AM, Rosenfeldt M, Saliba AE, Dobrindt U, Kalogirou C, Aguilar C
Nature microbiology 2026 Feb;11(2):535-550
Nature microbiology 2026 Feb;11(2):535-550
Sulfated Pelvetia siliquosa Polysaccharides Attenuate Pyroptosis via NF-κB Pathway Inhibition Against Calcium Oxalate Stone Formation.
Tong XY, Chen XW, Zhang JY, Ouyang JM
Marine drugs 2026 Feb 8;24(2)
Marine drugs 2026 Feb 8;24(2)
DMBX1 expression in colon cancer and its impact on prognosis and the tumor microenvironment.
Zhang K, Hu X, Chen J, Zhao Z, Yin X, Zhou L, Wang B
BMC medical genomics 2026 Feb 3;19(1)
BMC medical genomics 2026 Feb 3;19(1)
Inhibition of macrophage pyroptosis protects against sepsis-induced injury to the alveolar epithelial barrier.
Wang M, Zhang C, Li C, Zhang D
Journal of thoracic disease 2026 Feb 28;18(2):57
Journal of thoracic disease 2026 Feb 28;18(2):57
Bacteroides coprocola protects dopaminergic neurons in rotenone-induced Parkinson's disease mouse model by modulating gut microbiota dysbiosis and inhibiting the NLRP3 signaling pathway.
Liu Z, Nie J, Li Y, Huang M, Chen Z, Yu S, Zheng J, Tan Y, Chen S
Translational neurodegeneration 2026 Feb 28;15(1)
Translational neurodegeneration 2026 Feb 28;15(1)
The Protective Effects and Underlying Mechanisms of Taraxacum kok-saghyz Polysaccharides Against Intestinal Dysbiosis-Induced Mastitis Were Elucidated Using a Murine Model of the "Gut-Mammary" Axis.
Liang Y, Huang P, Li J, Manafu Z, Wang R, Chen X, Zhang X, Wu Y, Malajiang X, Yiming A, Duishan S, Wusiman A
Animals : an open access journal from MDPI 2026 Feb 27;16(5)
Animals : an open access journal from MDPI 2026 Feb 27;16(5)
Self-Assembled Rg3/Naringenin Nanoparticles for Targeted Brain Delivery: A Promising Therapeutic Approach for Early Alzheimer's Disease.
Lou X, Ni Z, Cui S, He Z, Zong Y, Chen W, Geng J, Zhou J, Li Z, Zhao Y, Teng H
Pharmaceuticals (Basel, Switzerland) 2026 Feb 26;19(3)
Pharmaceuticals (Basel, Switzerland) 2026 Feb 26;19(3)
Cobalt Metal-organic Framework Alleviates DSS-Induced Ulcerative Colitis Via Barrier-protective and Immunomodulatory Effects.
Abbas M, Suliman K, Chen M, Ying Z, Ashaq MS, Asif A, Khan MA, Chen D, Xie S
Biological trace element research 2026 Feb 25;
Biological trace element research 2026 Feb 25;
Gut microbiota-derived trimethylamine N-oxide contributes to cardiomyocyte pyroptosis and cardiac injury via the tRF-Glu-ANT1-GSDMD axis.
Wang T, Ren W, Chen X, Wang X, Liu M, Zhang Y, Li Z, Wang Y, Song Z, Diao H
Cellular & molecular biology letters 2026 Feb 24;31(1)
Cellular & molecular biology letters 2026 Feb 24;31(1)
TAS2R46 activation protects intestinal barrier from chronic high glucose.
Wang JM, Tian S, Duan JY, Zhang CP, Liu YW
Brain, behavior, and immunity 2026 Feb 24;135:106516
Brain, behavior, and immunity 2026 Feb 24;135:106516
Gut microbiota dysbiosis contributes to diabetic nephropathy via affecting renal lipid deposition and inflammatory responses.
Liu P, Hu P, Jin M, Wan Y, Wu J, Sun W, Tang Y, Huang L, Zhang D, Shi D, Xie T, Tong Y, Zheng H, Wang L, He H, Xu X
Journal of translational medicine 2026 Feb 23;24(1)
Journal of translational medicine 2026 Feb 23;24(1)
Construction of an In Vitro Blood-Brain Barrier Micro-Organoid Model Using Decellularized Squid Mantle Scaffold Film.
Sun H, Diao X, Feng J, Wang H, Elango J, Wu W
Journal of functional biomaterials 2026 Feb 23;17(2)
Journal of functional biomaterials 2026 Feb 23;17(2)
Gut Lachnospiraceae improves white matter injury-related cognitive decline by increasing L-arginine.
Xu Y, Huang L, Sun L, Li C, Zhou C, Liu P, Zhang Z, Deng S, Mao C, Hu Z, Bao X, Xia S, Xu Y
Cellular & molecular biology letters 2026 Feb 22;31(1)
Cellular & molecular biology letters 2026 Feb 22;31(1)
Butyrate ameliorates doxorubicin-induced heart failure by inhibiting cardiomyocyte ferroptosis through the gut-heart axis.
Zeng S, Xie Q, Zhang R, Yang T, Liu D, Zhang J, Ma S, Qiu X
iScience 2026 Feb 20;29(2):114754
iScience 2026 Feb 20;29(2):114754
Adenosine from high-fat-diet-tolerant monkey-derived Limsolactobacillus reuteri MacFasB02 modulates cholesterol metabolism to alleviate hyperlipidemia and inflammation.
Jin Y, An HJ, Zheng TT, Li JJ, Gao JM, Zhong XL, Li BH, Liu YY, Zhuang XJ, Chen JH, Rao JH
NPJ science of food 2026 Feb 20;10(1)
NPJ science of food 2026 Feb 20;10(1)
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
Yang Y, Yan K, Tang Y, Liu Z, Zhu L, Wei M, Huang C, Liu Z, Zhao D, Ren S
Investigative ophthalmology & visual science 2026 Feb 2;67(2):47
Investigative ophthalmology & visual science 2026 Feb 2;67(2):47
Metagenomics and Machine Learning Identify TMA-Producing Serratia Induced by High-Fat/Choline Diet: A Novel Obesity Target for TMA.
Wang Z, Wei J, Huang Z, Liu X, Li S, Fang Z, Hu L, Li R, Tao L, Li C, Chen H
Nutrients 2026 Feb 17;18(4)
Nutrients 2026 Feb 17;18(4)
Development and characterization of immortalized mouse intestinal epithelial cell lines.
Zhou JY, Espenschied ST, Lu Q, Karell PE, Lewis KJ, Newhall KP, Han Y, Bambroo M, Job A, Stappenbeck TS
Scientific reports 2026 Feb 11;16(1)
Scientific reports 2026 Feb 11;16(1)
Lactiplantibacillus plantarum GUANKE ameliorates influenza a virus-induced inflammation and lung barrier dysfunction through enhancing mitophagy and improving oxidative phosphorylation.
Lu S, Yue K, He S, Mi J, Yang T, Yang Y, Ma H, Ren Z, Ren L, Xu J
Cellular and molecular life sciences : CMLS 2026 Feb 10;83(1):107
Cellular and molecular life sciences : CMLS 2026 Feb 10;83(1):107
Integrating serum pharmacochemistry, network pharmacology, gut microbiota and transcriptomic strategies to reveal the active ingredients and mechanism of Changma Xifeng tablet in the treatment of tourette syndrome.
Zhu C, Shi Y, Zhou Z, Shao Y, Wang J, Sun Z, Bian M
Journal of ethnopharmacology 2026 Feb 10;356:120830
Journal of ethnopharmacology 2026 Feb 10;356:120830
Glimepiride alleviates blood-brain barrier disruption and neuroinflammation in mice with intracerebral haemorrhage.
Zhou H, Wang Q, Liu Y, Zhang X, Chen Y, Guo P, Yong VW, Xue M
Annals of medicine 2026 Dec;58(1):2663133
Annals of medicine 2026 Dec;58(1):2663133
Gut-confined fullerene reprograms lactate metabolism to Rescue hypoxia-induced exercise intolerance.
Chen S, Pan Y, Liu M, Liu C, Xu Y, Ma J, Li J, Wang X, Yang L, Wang Y, Li B, Wang Z, Zhang Y, Shen H, Wulan Q, Li J, Wang C, Bai C
Biomaterials 2026 Aug;331:124075
Biomaterials 2026 Aug;331:124075
Caspase-4/11-mediated non-canonical pyroptosis disrupts blood-brain barrier integrity via VEGFA/VEGFR2 signaling in Escherichia coli meningitis.
Du Y, Yu X, Lu Y, Jia K, Peng L, Fang R, Zhang J, Li Z
Microbiological research 2026 Aug;309:128531
Microbiological research 2026 Aug;309:128531
Atractylenolide III Alleviates the Lipid Metabolic Disorders in Ovariectomy-Induced Estrogen-Deficient Mice Through Repairing Intestinal Inflammation and Microenvironment.
Yanyan X, Yanyu Q, Qiao G, Jiabo G, Desong K, Heiying J
The journal of obstetrics and gynaecology research 2026 Apr;52(4):e70272
The journal of obstetrics and gynaecology research 2026 Apr;52(4):e70272
Qiming Granules Ameliorate Diabetic Retinopathy by Regulating the PI3K/Akt Signaling Pathway.
Zhou L, Qin T, Lv Y, Wu Z
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2026 Apr;42(3):202-212
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2026 Apr;42(3):202-212
Carrier-free supramolecular architectonics of quercetin-berberine for safety-redefined therapy of ulcerative colitis.
Zhang X, Fu Y, Liu S, Zhang J, Xu F, Zhang C, Wang Y, Huo C
Materials today. Bio 2026 Apr;37:102970
Materials today. Bio 2026 Apr;37:102970
Intestinal epithelial protection and gut microbiota modulation by Ganoderma lucidum proteoglycan are associated with its hypoglycemic potential in type 2 diabetes.
Zhang Q, Chen J, Zhang Y, Wang Y, Li J, Pan Y, Zhang Z, Yang H, He Y, Zhou P
International journal of biological macromolecules 2026 Apr;354:151441
International journal of biological macromolecules 2026 Apr;354:151441
HSP70 preserves brain microvascular endothelial integrity under heat stress associated with suppressed JNK-mediated apoptosis and mitophagy.
Zhou M, Li H, Wan M, Ji Z, Liu Z, Wan Z, Cai J, Shi J, Qiu X, Zhang X
International journal of biological macromolecules 2026 Apr;353:151239
International journal of biological macromolecules 2026 Apr;353:151239
Panax notoginseng saponins protect the blood-brain barrier against oxidative stress by activating the Akap12-PI3K/AKT-AQP1 signaling axis.
Fan L, Qu S, Miao C, Wu D, Rao Y, Xu W, He Y, Ding R, Song G
International journal of biological macromolecules 2026 Apr;353:151045
International journal of biological macromolecules 2026 Apr;353:151045
Inhibition of Transglutaminase 2 Preserves Blood-Brain Barrier Integrity and Improves Neurological Outcomes After Experimental Traumatic Brain Injury in Mice.
Yang J, Zhang L, Qiu X, Wang J, Yan R, Ye J, Peng J, Jiang Y
CNS neuroscience & therapeutics 2026 Apr;32(4):e70887
CNS neuroscience & therapeutics 2026 Apr;32(4):e70887
Remimazolam alleviates blood-brain barrier damage by regulating the PI3K/AKT signaling pathway in sepsis-associated encephalopathy mice.
Xu B, Wang X, Liu S, Guo Y, Dong Q, Tao Y, Zhang M, Ni P, Xie Y
Brain research bulletin 2026 Apr;237:111824
Brain research bulletin 2026 Apr;237:111824
Protective Effects of Bifidobacterium bifidum Strains with IgA-Potentiating Activity Against ETEC Infection in Weanling Mice.
Zhao M, Ma Q, Meng Y, Hung W, Zhao W, Zeng Z, Yi H, Zhang L, Zhang Z
Probiotics and antimicrobial proteins 2026 Apr;18(3):4598-4609
Probiotics and antimicrobial proteins 2026 Apr;18(3):4598-4609
Integrated network pharmacology, transcriptomics and experimental validation to explore mechanisms of Wenyang Jiedu Granule on IAV-induced pneumonia.
Qin S, Chen T, Wang Y, Ke H, Xin J, He W, Guo Y, Niu Z, Hua Q, Yang Z, Liu Y, Zhang Z
Chinese herbal medicines 2026 Apr;18(2):241-261
Chinese herbal medicines 2026 Apr;18(2):241-261
Polystyrene microplastics exposure increases the disruption of intestinal barrier integrity and gut microbiota homeostasis during obesity and aging.
Wei G, Liu W, Shen F, Xie R, Wang F, Guo H, Liu L
Journal of environmental sciences (China) 2026 Apr;162:430-443
Journal of environmental sciences (China) 2026 Apr;162:430-443
Mechanism of Gzma-mediated GEF-H1 activation in intestinal epithelial cells leading to intestinal barrier dysfunction in sepsis.
Lin Z, Jiang H, Ni C, Deng L, Yang H, Wang R, Liu P, Li X, Yu Y, Li W, Liao B, Liu J, Li W, Yang J, Chao Y, Liu H, Wu X, Ren J, Zhao Y
Clinical and translational medicine 2026 Apr;16(4):e70651
Clinical and translational medicine 2026 Apr;16(4):e70651
The ovarian tumor domain-containing protein 4 (OTUD4)-targeted ferroptosis inhibitor Maclekarpine E attenuates ulcerative colitis.
Lv X, He Z, Xue J, Yang Y, Tang Y, Cai H, Luo H, Li X, Dong Z, Liu Y, Zeng J, Yang Z, Cheng P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157999
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157999
Brucea javanica oil emulsion ameliorates ulcerative colitis by upregulating Deoxyribonuclease 2 to suppress cytosolic DNA-sensing signaling.
Ren M, Liu C, Lai J, Huang W, Wang J, Tu J, Yang B, Su Z, Han Q, Lai Z, Chen J, Liang Q, Xie Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157980
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157980
Xanthoxylin alleviates dextran sulfate sodium (DSS)-induced colitis by targeting macrophage infiltration via the tumor necrosis factor (TNF) /nuclear factor-kappa B (NF-κB) signaling pathway.
Chen Y, Chen Z, Li J, Zhao R, Chen Q, Zhong C, Lu M, Shi Y, Wang L, Bao L, Zuo Z, Mao X, Wu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157971
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157971
Homoplantaginin alleviates high glucose-induced vascular endothelial barrier dysfunction by regulating Yes-associated protein 1.
Li X, Wang J, Wang L, Sha X, Huang S, Ren M, Cheng L, Zhang Y, Zhou W, Lin Y, Wu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157953
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157953
Jiawei Danxuan Koukang and Its Component Kaempferol Alleviate Oral Submucous Fibrosis by Restoring Epithelial-Fibroblast Homeostasis and Suppressing Neutrophil Recruitment via the ANXA1/FPR2 Axis.
Xiao Y, Tan Y, Liu Y, Chen R, Zhou T, Hu Z, Tan J
Food science & nutrition 2026 Apr;14(4):e71785
Food science & nutrition 2026 Apr;14(4):e71785
ADAMTS2 Modulates Inflammation, Autophagy, and Barrier Integrity Through PI3K/AKT/mTOR Signaling in LPS-Induced Acute Respiratory Distress Syndrome.
Gao S, Lyu T, Quan Y, Tao Y, Wang W, Xu X
Immunity, inflammation and disease 2026 Apr;14(4):e70429
Immunity, inflammation and disease 2026 Apr;14(4):e70429
Polydopamine-Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus.
Wu R, Liu M, Gao C, Zhao C, Zhao F, Dong S, Zhang B, Liu Q, Zhang W, Zhao M, Lu Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e22637
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e22637
Diabetes Mellitus Facilitates Gallstone Formation Through CXCR2-NETs-Mediated Liver-Bile Barrier Damage.
Shi C, Feng S, Liu T, Meng Z, Zheng Y, Huang Z, Wang T, Zhang B, Xue D, Ma B, Meng X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e19500
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(24):e19500
Neuroprotective Effects of Time-Restricted Feeding Combined With Different Protein Sources in MPTP-Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism.
Li T, Wu J, Zhou SY, Li MA, Zhao LP, Wang A, Song YZ, Huang WY, Tan LL, Qiao CM, Zhao WJ, Cui C, Shen YQ
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e16502
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e16502
Advanced glycation end products promote Porphyromonas gingivalis dissemination via an ROS-dependent, inflammation-independent mechanism.
Liu Y, Zhu C, Mao C, Zhang X, Wang M, Xu X, Guo M, Zhang R, Guan C, Wang C, Ye K, Xu D
Cell reports 2026 Apr 8;45(4):117252
Cell reports 2026 Apr 8;45(4):117252
RhoB supports rubella infection and impairs endothelial barrier integrity through downstream ROCK signaling.
Kovacevic I, Müller M, Mair L, Henschke V, Kowalski A, Boeckel JN, Kropf K, Posern G, Reibetanz U, Claus C
Cell communication and signaling : CCS 2026 Apr 27;24(1)
Cell communication and signaling : CCS 2026 Apr 27;24(1)
Head-down position after reperfusion improves cerebral ischaemic injury in rat.
Wu Q, Zhang NN, Cai JR, Zhang YN, Chen HS
Stroke and vascular neurology 2026 Apr 27;11(2):208-217
Stroke and vascular neurology 2026 Apr 27;11(2):208-217
Oral Exposure to Polypropylene Microplastics Exacerbates Cow's Milk Allergy in a Murine Model by Skewing the DCs/T-Cell Response toward Th2 Polarization.
Shi Q, Wang Z, Luo H, Chen C, Chen Y, Li X, Xie Y, Zheng S, Meng X, Wu Y, Gao J, Chen H
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12461-12474
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12461-12474
Ophiopogon japonicus Polysaccharides Promote Microbial Production Of Chenodeoxycholic Acid To Alleviate Ulcerative Colitis in Mice by Inhibiting the STING1-Related NF-κB Pathway.
Gao X, Zhang C, Zhao Z, Chen Y, Lei H, Cao Z, Yu W, Lin W, He Y, Li X, Xiang Q, Zhang Z, Zhang L, Chen G
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12087-12101
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12087-12101
Vitamin D(3) Metabolite-Enhanced Hepatic VDR-FXR Binding Attenuates Bile Acid Dysregulation-Induced Diarrhea in Weaned Piglets.
He L, Wu J, Wang Y, Jiao Y, Zhang F, Lin Z, Liu Q, Feng Y
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12069-12086
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12069-12086
Biomimetic mitochondria-targeted drug delivery system for the treatment of inflammatory bowel disease.
Jia F, Deng Y, Xu Y, Wu J, Liu S, Huang Y
Journal of controlled release : official journal of the Controlled Release Society 2026 Apr 22;395:114927
Journal of controlled release : official journal of the Controlled Release Society 2026 Apr 22;395:114927
Gut microbiota: A critical regulator of oxaliplatin-induced peripheral neurotoxicity development.
Liu Z, Zhang T, Wang S, Yin H, Shao X, Gao L, Lu X
Neurotoxicology 2026 Apr 21;114:103460
Neurotoxicology 2026 Apr 21;114:103460
Macrophages with ITIH4 overexpression attenuate inflammatory responses and regulate intestinal epithelial cells.
Li J, Zhao Z, Fei J, Zhang R, Pan L, Xiang Y, Hong L, Zhan Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 17;75(1)
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 17;75(1)
Atmospheric particulate matter impairs pulmonary barriers by triggering FTH1-mediated ferroptosis.
Yue H, Wang J, Li Y, Dong H, Dong Y, Liu T, Li J
iScience 2026 Apr 17;29(4):115177
iScience 2026 Apr 17;29(4):115177
Metabolic Engineering of Commensal Bacteria for Producing 5-Hydroxyindoleacetic Acid as a Therapeutic Strategy for Colitis.
Du W, Zhang C, Zou ZP, Shan S, Wang LS, Jiang W, Yin BC, Ye BC, Zhou Y
ACS synthetic biology 2026 Apr 17;15(4):1412-1425
ACS synthetic biology 2026 Apr 17;15(4):1412-1425
Intermittent fasting protects MPTP-induced Parkinson's disease mouse model through regulating gut microbiota dysbiosis.
Qu Y, Wang P, Wang D, Li B, Yang F
International immunopharmacology 2026 Apr 15;175:116447
International immunopharmacology 2026 Apr 15;175:116447
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
Zhang H, Chang Y, Fu Q, Jin T, Zhang S, Zhang M
International immunopharmacology 2026 Apr 15;175:116417
International immunopharmacology 2026 Apr 15;175:116417
Phenethyl Isothiocyanate Suppresses Hepatocellular Carcinoma Progression and Immune Evasion via ZNF652 Regulation of PD-L1.
Ren D, Wu J, Zhu J, Xie C, Zhong C, Cao H, Han H, Zhu J
Phytotherapy research : PTR 2026 Apr 15;
Phytotherapy research : PTR 2026 Apr 15;
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus.
Guan J, Zhou D, Shao R, Liu X, Peng J, Huang Y, Qi S, Xi C, Wang M, Sun B, Qi Y, Yin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 13;:e75255
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 13;:e75255
Hexavalent chromium exposure disrupts gut microbial structure and metabolic function in broiler chickens.
Yang Q, He S, Xiang B, Chen Y
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr 12;95:127874
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr 12;95:127874
Abnormal glycosylation of MUC20 mediates TAM polarization and promotes immune escape in colorectal cancer.
Zhi Y, Zhang Y, Fei H, Yuan J, Liu X, Liu W
Communications biology 2026 Apr 11;
Communications biology 2026 Apr 11;
Puerarin Alleviates Depression via Integrated Regulation of TLR4/MyD88/NF-κB Signaling and Gut Microbiota-Metabolic Axis.
Cao XY, Tian JJ, Zhang W, Chen CL, Ma H
Neurochemical research 2026 Apr 10;51(2)
Neurochemical research 2026 Apr 10;51(2)
Integrated transcriptomic and metabolomic analyses reveal distinct energy metabolic signatures and functional properties of RPE cells under two culture conditions.
Zhang F, Wang C, Tang Q, Ao T, Li J, Liu Y
Scientific reports 2026 Apr 10;16(1)
Scientific reports 2026 Apr 10;16(1)
LncRNA RP11-510J16.3 exacerbates sepsis-associated encephalopathy by facilitating NLRP3-dependent pyroptosis through miR-1290 sequestering.
Liu X, Xiao Y, Lai Y, Ding H, Wen Y, He Z, Chen M, Han Y, Jing Y, Wen M
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 1;75(1)
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2026 Apr 1;75(1)
PCYT1A Hypophosphorylation Underlies Retinal Lipid Dysregulation in CERKL Retinitis Pigmentosa and Is Therapeutically Reversed by Phosphatidylcholine.
Gao P, Li P, Qin Y, Hu H, Reilly J, Fu Y, Wang Q, Ren M, Luo J, Zhu Y, Dai L, Shu X, Ren X, Liu F, Liu M, Xu C, Tang Z
Investigative ophthalmology & visual science 2026 Apr 1;67(4):54
Investigative ophthalmology & visual science 2026 Apr 1;67(4):54
Probiotic Bifidobacterium Confers Protection Against Heat Stroke Through Enhancement of Intestinal Barrier Function in Rats.
Cai G, Chen Y, Chen J, Zhang J, Cai J, Fan Q, Zhang Y, Tang Y, Huang J, Xia G, Wang C, Feng A, Nie X
Shock (Augusta, Ga.) 2026 Apr 1;65(4):686-699
Shock (Augusta, Ga.) 2026 Apr 1;65(4):686-699
Airborne PM(2.5) from pig houses induces piglet respiratory epithelial barrier injury by activating the NLRP3 inflammasome through Drp1-mediated mitochondrial dysfunction.
Tang Q, Wang C, Wang Y, Mao H, Deng K, Shen D, Zhang M, Li C
Ecotoxicology and environmental safety 2026 Apr 1;314:120072
Ecotoxicology and environmental safety 2026 Apr 1;314:120072
An indoloquinolinone 3a alleviates lipopolysaccharide-induced acute lung injury by modulating the NF-κB and AMPK/Nrf2 signaling pathways.
Tian W, Liu Z, Liu J, Kong L, Qin H, Zhu GY, Zhang W, Jin J, Wang X, Jiang ZH, Bai LP
International immunopharmacology 2026 Apr 1;174:116398
International immunopharmacology 2026 Apr 1;174:116398
Increased PRSS56 expression is a causal factor and therapeutic target for human axial high myopia.
Wu B, Zeng W, Tang K, Xiong J, Mo X, Fu Q, Fu D, Chu R, Zhao G, Lu L, Wang Z, Wu L, Yu Z, Zhou X, Wang H
Cell research 2026 Apr 1;
Cell research 2026 Apr 1;
Predictive value of plasma zonulin for postoperative Hirschsprung-associated enterocolitis.
Wu L, Gao Y, Zhou R, Xiao P, Zhang Z, Li B, Pierro A, Li L, Jiang Q, Li Q
World journal of pediatric surgery 2025;8(3):e001057
World journal of pediatric surgery 2025;8(3):e001057
Canine-derived Weissella confusa ZJUIDS-D034 and Enterococcus faecalis ZJUIDS-D016 combat aging by regulating gut microbiota.
Chen N, Yu Z, Ji X, Zhang S, Yu C, Valencak TG, Shi F, Ren D
Current research in microbial sciences 2025;8:100381
Current research in microbial sciences 2025;8:100381
The role of the gut microbiota and the nicotinate/nicotinamide pathway in rotenone-induced neurotoxicity.
Sai Y, Ge W, Zhong L, Zhang Q, Xiao J, Shan Y, Ye W, Liu H, Liu S, Ye F, Wang X, Tang H, Zhao Y, Dan G
Current research in toxicology 2025;8:100212
Current research in toxicology 2025;8:100212
A Hepatic Oxidative Metabolite of Palmatine Ameliorates DSS-Induced Ulcerative Colitis by Regulating Macrophage Polarization Through AMPK/NF-κB Pathway.
Huang QT, Ma XD, Zhang JN, Lin WX, Shen XX, Huang ZW, Zhang X, Wu XY, Dou YX, Su ZR, Su JY, Li YC, Liu YH, Xie YL, Lin RF, Huang HY, Zhang QH, Huang XQ
The American journal of Chinese medicine 2025;53(1):285-307
The American journal of Chinese medicine 2025;53(1):285-307
α-hederin Targets USP5 to Inhibit Colorectal Tumorigenesis by Disrupting STAT3 Deubiquitination.
Feng H, Wang Q, Li L, Tao L, Zeng S, Li Z, Fan M, Yu C, Sun D, Shen W, Cheng H
International journal of biological sciences 2025;21(15):6697-6722
International journal of biological sciences 2025;21(15):6697-6722
Comparisons of the Effects of Low- or High-Fat Diets Rich in Soybean Oil, Lard, and Tea Seed Oil on Markers of Blood-Brain Barrier and Neuroinflammation in Ovariectomized Mice.
Lin SH, Soetanto CG, Chiu WC, Cross TL, Kao NJ, Wu YR, Lin CI, Jha P
International journal of food science 2025;2025:4154633
International journal of food science 2025;2025:4154633
Integrating network pharmacology and experimental verification to explore the protective effects of Evodia rutaecarpa in ischemic stroke.
Huang Z, Liu J, Li H, Huang H, Ai Y, Zhou D
PloS one 2025;20(6):e0327133
PloS one 2025;20(6):e0327133
LncRNA NEAT1 protects uremic toxin-induced intestinal epithelial barrier injury by regulating miR-122-5p/Occludin axis.
Han M, P P, Tian J, Wang C, Zhou S, Fu L, Wang L, Tian N
PloS one 2025;20(5):e0322989
PloS one 2025;20(5):e0322989
Curcumin ameliorates aging-induced blood-testis barrier disruption by regulating AMPK/mTOR mediated autophagy.
Xue C, Yan Z, Cheng W, Zhang D, Zhang R, Duan H, Zhang L, Ma X, Hu J, Kang J, Ma X
PloS one 2025;20(4):e0321752
PloS one 2025;20(4):e0321752
Curcumin modulated gut microbiota and alleviated renal fibrosis in 5/6 nephrectomy-induced chronic kidney disease rats.
Li C, Chen X, Yao J, Zha W, Li M, Shen J, Jiang H, Tian P
PloS one 2025;20(1):e0314029
PloS one 2025;20(1):e0314029
Functional Liposomes Improve the Oral Absorption of Lurasidone Hydrochloride by Overcoming Multiple Absorption Barriers and Eliminating Food Effect.
Song T, Wang W, Wu Y, Liu C, Yuan L, Sun Z, Zhang J, Sun Y
International journal of nanomedicine 2025;20:4883-4901
International journal of nanomedicine 2025;20:4883-4901
SIGIRR Alleviates Intestinal Mucosal Damage in Severe Acute Pancreatitis via the TLR4 Signaling Pathway.
Liu Y, Zhou F, Song Y, Wei S, Cheng B, Liu D, Xiong H, Xie Y, Zhou X
Cellular and molecular gastroenterology and hepatology 2025;19(12):101608
Cellular and molecular gastroenterology and hepatology 2025;19(12):101608
Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways.
Zhu D, Wu XY, Li LC
International journal of ophthalmology 2025;18(8):1426-1432
International journal of ophthalmology 2025;18(8):1426-1432
Gegen Qinlian Decoction Ameliorated DSS-Induced Colitis by Attenuating Inflammation, Restoring Intestinal Mucosal Barrier and Modulating Gut Microbiota.
Wang Y, Yan R, Ye L, Tang C, Zhou H, Zhao G
Journal of inflammation research 2025;18:8065-8084
Journal of inflammation research 2025;18:8065-8084
Spermidine Exerts Neuroprotective Effects Following Intracerebral Hemorrhage in Mice Through Anti-Inflammation and Blood-Brain Barrier Protection.
Qi L, Zhang X, Liu Y, Guo P, Siddique R, Mazhar M, Xue S, Yong VW, Xue M
Journal of inflammation research 2025;18:7401-7417
Journal of inflammation research 2025;18:7401-7417
Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway.
Wang T, Ou Y, Xiong W, Luo L, Xu Y, Chen G, Peng Y, Chen Y, Zeng H, Yu Y, Tang H, Yao H, Wang W
Journal of inflammation research 2025;18:7301-7321
Journal of inflammation research 2025;18:7301-7321
Kuiyangling Enema Alleviates Ulcerative Colitis Mice by Reducing Levels of Intestinal NETs and Promoting HuR/VDR Signaling.
Zhang D, Zhu Z, He Z, Duan S, Yi Q, Qiu M, Dai X, Su G, Li K, Xu L, Liu D, Wu Y, Gao Y, Li R, Guo S
Journal of inflammation research 2025;18:381-403
Journal of inflammation research 2025;18:381-403
Tenascin-C Facilitates Microglial Polarization via TLR4/MyD88/NF-κB Pathway Following Subarachnoid Hemorrhage.
Hu ZQ, Ma R, Sun JQ, Peng M, Yuan J, Lai N, Liu J, Xia D
Journal of inflammation research 2025;18:3555-3570
Journal of inflammation research 2025;18:3555-3570
Berberine Repairs Intestinal Mucosal Barrier by Targeting HSP90AA1 and MAPK14.
Zhao D, Zhai Y, Chen C, Chen J, Chen D, Yang Q, Yu Z, Shao S, Huang Y, Shu J
Pharmacogenomics and personalized medicine 2025;18:263-278
Pharmacogenomics and personalized medicine 2025;18:263-278
Isoorientin Modulates Gut Microbes and Their Metabolites to Alleviate Caco-2 Cell Monolayer Inflammation by Reducing Intestinal Permeability via P-Gp/eCBs.
Wang Z, Jiang Y, Duan B, Zhang H, Li A, Yang J, Lv M, Yang J
Journal of inflammation research 2025;18:14365-14379
Journal of inflammation research 2025;18:14365-14379
Yuyang Decoction Regulates Macrophage Polarization and Repairs the Intestinal Mucosal Barrier via the TLRs/Tollip Signaling Pathway.
Lian J, Jin G, Li J, Zhang W, Chang Y, Li W, Zhi H, Tian J, Liang C, Su J
Journal of inflammation research 2025;18:10499-10518
Journal of inflammation research 2025;18:10499-10518
Network pharmacology-guided investigation of Fuzheng Yanggan Huaxian decoction in a CCL(4)-induced hepatic fibrosis mouse model: involvement of the TLR4-MAPK/NF-κB signaling axis and intestinal barrier.
Ma J, Zang X, Li X, Xu M, Zhang S, Chen X, Zhu T, Luan Y, Chen X, Qiu Y
American journal of translational research 2025;17(9):6795-6810
American journal of translational research 2025;17(9):6795-6810
Dysregulation of the microbiota-gut-brain axis induced by chronic pancreatitis mediates anxiety- and depression-like behaviors in mice.
Liu L, Zhang X, Wang C, Zhou K, Bao J, Cheng Z, Sun H, Zhu C, Yu G, Xiao W, Wan R
Frontiers in immunology 2025;16:1753424
Frontiers in immunology 2025;16:1753424
Deciphering immune cell interaction aberrations in necrotizing enterocolitis: the regulatory role of DHRS7.
Gao K, Chen Y, Lu J, Ge W, Yin Q
Frontiers in immunology 2025;16:1743878
Frontiers in immunology 2025;16:1743878
Nrf2/HO-1-dependent inhibition of ferroptosis underlies the antioxidant effects of 5-O-methylvisammioside in colitis.
Li D, Xu F, Wang W, Jiang C, Cui W, Guan ZA, Gu C
Frontiers in immunology 2025;16:1738408
Frontiers in immunology 2025;16:1738408
Dahuang gancao dandelion decoction regulates intestinal flora and inhibits NF-κB/ARA signaling pathway to alleviate ulcerative colitis.
Malajiang X, Shen WE, Aersilan A, Liu M, Liang Y, Wang S, Abula S, Wusiman A
Frontiers in immunology 2025;16:1735021
Frontiers in immunology 2025;16:1735021
Akkermansia muciniphila and its culture supernatant ameliorate colitis in interleukin-10 knockout mice via gut barrier and immune modulation.
Jiang M, Jia Y, Ma C, Zeng Z, Li Y, Li L, Lin H, Pang J, Li J, Chen J, Li X, Chen K, Zhang H, Gan Y, Xiang Z, Chen L, Zhang H
Frontiers in immunology 2025;16:1693007
Frontiers in immunology 2025;16:1693007
Macrophage TRIM21 lactylation exacerbates infection-induced orchitis through enhancing STAT1-mediated CXCL9 and CXCL10 production.
Tang W, Chen W, Li N, Li W, Lei Z, Sun W, Xie X, Jiang Y, Chen Y, Xu L, Zhu J, Li Y, Sha J, Dai Y, Zhou S, Chen X, Su C
Frontiers in immunology 2025;16:1684836
Frontiers in immunology 2025;16:1684836
Lyophyllum decastes-derived polysaccharides alleviate DSS-induced colitis in mice by suppressing inflammation, enhancing intestinal barrier integrity, and restoring gut microbiota homeostasis.
Ghaleb E, Alioui Y, Yazeed J, Wahan N, Bashah A, Al-Waqeerah A, Atta A, Sun Y, Xin Y, Wang L, Feng B, Mao W
Frontiers in pharmacology 2025;16:1644325
Frontiers in pharmacology 2025;16:1644325
Barnesiella intestinihominis improves gut microbiota disruption and intestinal barrier integrity in mice with impaired glucose regulation.
Liu X, Wang L, Huang B, Jiao Y, Guan Y, Nuli R
Frontiers in pharmacology 2025;16:1635579
Frontiers in pharmacology 2025;16:1635579
Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin.
Bai Q, Zhao Z, Duan Y, Cai R, Chen Y, Zhou C, Tian X, Yang Y, Wu H, Li M, You J, Song Q, Dong H, Liu T
Frontiers in microbiology 2025;16:1594012
Frontiers in microbiology 2025;16:1594012
Schisandrin B alleviates metabolic associated fatty liver disease by regulating the PPARγ signaling pathway and gut microbiota in mice.
Wan J, Lang C, Gao M, Liu F, Feng X, Li H, Wang C, Sun J
Frontiers in pharmacology 2025;16:1583307
Frontiers in pharmacology 2025;16:1583307
2-Dodecyl-6-methoxycyclohexa-2,5-dien-1,4-dione alleviates liver fibrosis and improves intestinal flora and bile acid metabolism.
He Y, Hoa Pham TT, Xu J, Hong S, Wang J, Zhai H, Tao Q, Li R, Zhang G, Shi X
Frontiers in pharmacology 2025;16:1581138
Frontiers in pharmacology 2025;16:1581138
Metformin improves intestinal ischemia-reperfusion injury by reducing the formation of mitochondrial associated endoplasmic reticulum membranes (MAMs) and inhibiting ferroptosis in intestinal cells.
Zhao X, Yan L, Tian L, Zhang X, Liu R, Li Z
Frontiers in pharmacology 2025;16:1581085
Frontiers in pharmacology 2025;16:1581085
Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice.
Tang R, Jiang L, Ji Q, Kang P, Liu Y, Miao P, Xu X, Tang M
Frontiers in pharmacology 2025;16:1572906
Frontiers in pharmacology 2025;16:1572906
Roles of MASP-1 and MASP-3 in the development of retinal degeneration in a murine model of dry age-related macular degeneration.
Omori T, Machida T, Ishida Y, Sekiryu T, Sekine H
Frontiers in immunology 2025;16:1566018
Frontiers in immunology 2025;16:1566018
Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia.
Zhao J, Fu Y, Qiu H
Frontiers in microbiology 2025;16:1555734
Frontiers in microbiology 2025;16:1555734
Umbelliferone as an effective component of Rhodiola for protecting the cerebral microvascular endothelial barrier in cSVD.
Tang L, Cheng H, Yang Q, Xie Y, Zhang Q
Frontiers in pharmacology 2025;16:1552579
Frontiers in pharmacology 2025;16:1552579
Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway.
Wang S, Liu X, Xu L, Lang J, Liu D
Frontiers in immunology 2025;16:1537651
Frontiers in immunology 2025;16:1537651
Thlaspi arvense suppresses gut microbiota related TNF inflammatory pathway to alleviates ulcerative colitis.
Wang W, Zhao Y, Wang Z, Wang C, Bi L, Wang Y
Frontiers in immunology 2025;16:1537325
Frontiers in immunology 2025;16:1537325
Acupuncture alleviates hemorrhagic transformation after delayed rt-PA treatment for acute ischemic stroke by regulating the mitophagy-NLRP3 inflammasome pathway.
Jiang T, Liu Q, Liu H, Huang Z, Yang M, Huang P, Shen Y, Song Y, Xu W, Zhang X, Ni G
Frontiers in neurology 2025;16:1533092
Frontiers in neurology 2025;16:1533092
Aqueous extracts of Elsholtzia ciliata and Hovenia dulcis ameliorate loperamide-induced constipation in mice by promoting intestinal peristalsis and barrier function and the abundance of intestinal beneficial bacteria.
Wu J, Xin Q, Wang S, Zhang X, Jiang C
Frontiers in microbiology 2025;16:1531232
Frontiers in microbiology 2025;16:1531232
Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.
Chen C, Sun B, Chen K, Bao H, Tao Y, Zhou J, Yuan X, He L, Lu Z, Chen K, Li Y, Yu C, Chen Y, Zhang Y
Frontiers in pharmacology 2025;16:1530109
Frontiers in pharmacology 2025;16:1530109
Traditional Mongolian Medicine Qiqirigan-8 alleviates non-alcoholic fatty liver disease via restoring gut microbiota and metabolism.
Yang D, Wuyunsiqin, YanNiu, Hashentuya, Tana, Anna, Ma M, Zhao W, Menggenduxi, Wang M
Frontiers in microbiology 2025;16:1517082
Frontiers in microbiology 2025;16:1517082
Liqi Yangyin formula ameliorates CUMS-induced depression and comorbid constipation via ACE/FFAR2 modulation of the microbiota-gut-brain axis.
Xu L, Ong SS, Deng X, Qian Y, Lu H, Song Y, Wang Y, Xu T
Frontiers in cellular and infection microbiology 2025;15:1692110
Frontiers in cellular and infection microbiology 2025;15:1692110
Ellagic acid mitigates rotavirus-induced intestinal injury via bidirectional "immune-microbiota" regulatory effect.
Zheng J, Cao Z, Yousaf W, Haseeb A, Wang Z, Wang H
Frontiers in cellular and infection microbiology 2025;15:1686918
Frontiers in cellular and infection microbiology 2025;15:1686918
Porphyromonas gingivalis-induced periodontitis promotes neuroinflammation and neuronal loss associated with dysfunction of the brain barrier.
Jiang Y, Xu L, Zhao X, Shen H, Qiu C, He Z, Song Z, Zhou W
Frontiers in cellular and infection microbiology 2025;15:1559182
Frontiers in cellular and infection microbiology 2025;15:1559182
Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity.
Pang WL, Li TG, Wang YY, Song LY, Li L, Li XY, Qiu Y, Yang ZS
Frontiers in cellular and infection microbiology 2025;15:1528578
Frontiers in cellular and infection microbiology 2025;15:1528578
Chaihuang Qingyi Huoxue granule ameliorates severe acute pancreatitis by modulating gut microbiota and repairing the intestinal mucosal barrier.
Zhang X, Zeng X, Guo W, Zhou X, Zhang Y, Tang M, Fu J, Deng Y, Liang X, Zhao L, Li Z, Wang T, Li L, Xiao G
Frontiers in cellular and infection microbiology 2025;15:1514201
Frontiers in cellular and infection microbiology 2025;15:1514201
Histone lactylation exacerbates acute lung injury in septic mice by promoting ferroptosis in pulmonary microvascular endothelial cells.
Fang P, Li S, Lu ZQ, Xia DL, Xu MM, Pan JJ, Fu L, Sun GY, You QH
Burns & trauma 2025;13:tkaf056
Burns & trauma 2025;13:tkaf056
Fibroblast exosomes promote wound healing and improve the quality of healed skin via miR-29a-3p-mediated KEAP1/Nrf2 pathway activation.
Yan L, Fan D, Yang J, Wang J, Hu X, Zhang X, Huang Y, Wang H, Yin W, Cai X, Shang R, Huang C, Luo G, He W
Burns & trauma 2025;13:tkaf035
Burns & trauma 2025;13:tkaf035
Gasdermin E-mediated intestinal epithelial pyroptosis promotes chemically induced colitis in mice.
Wu YZ, Xie Y, Chen L, Ning L, Hu XQ, Xu XP
Gastroenterology report 2025;13:goaf021
Gastroenterology report 2025;13:goaf021
L-cysteine mitigates busulfan-induced testicular injury through modulation of CBS/H(2)S axis.
Liu S, Wei B, Wei H, Xu A, Sheng L, Sun X, Dong Y, Yang H
Frontiers in cell and developmental biology 2025;13:1679330
Frontiers in cell and developmental biology 2025;13:1679330
Preclinical evaluation of 6-Gingerol in modulating gut microbiota and SCFAs to mitigate Clostridium difficile-associated diarrhea in mice.
Ma FZ, Zhu L, Li M, Tang ZW, Yu XH, Zhang CE, Ma ZJ
Frontiers in chemistry 2025;13:1635781
Frontiers in chemistry 2025;13:1635781
Multi-omics elucidation of Lactiplantibacillus plantarum NKK20 in preventing PCOS via the gut-ovary axis: SCFAs-mediated microbiota-metabolite-immune crosstalk.
Xu H, Liu X, Sun W, Dong X, Liu X, Xie Y, He J, Ali A, Chen M, Wu L, Ma J, Shao K
Frontiers in nutrition 2025;12:1709581
Frontiers in nutrition 2025;12:1709581
The role of Sophora alopecuroides alkaloids in colon health of lambs fed high-concentrate diets for extended periods: impact on barrier function, antioxidation, and microflora.
Li S, Li B, Lu H, Zhao J, Gao A, An Y, Yang J, Wang H
Frontiers in veterinary science 2025;12:1698892
Frontiers in veterinary science 2025;12:1698892
Study on the role of the combination of quercetin and lutein in alleviating ulcerative colitis in mice.
Xu Z, Mi S, Chitrakar B, Wang L, Li Y, Shi R, Sang Y, Yu W, Wang X
Frontiers in nutrition 2025;12:1698231
Frontiers in nutrition 2025;12:1698231
Oral administration of curcumin and quercetin nanoparticles can improve ulcerative colitis by regulating intestinal microorganisms.
Li Y, Xu Z, Zhao S, Huang T, Xu J, Wang S, Sang Y, Yu W, Wang X
Frontiers in nutrition 2025;12:1696699
Frontiers in nutrition 2025;12:1696699
Therapeutic potential of Glycyrrhiza polysaccharides in pseudorabies virus infection: immune modulation, antioxidant activity, and gut microbiota restoration.
Song C, Wei Q, Shen H, Zhang X, Pan D, Zhang Z, Zhang Y, Yang S, Shu X
Frontiers in veterinary science 2025;12:1679013
Frontiers in veterinary science 2025;12:1679013
Vespa orientalis pupae peptide hydrolysates modulate NF-κB signaling in LTA-induced pneumonia from clinical Enterococcus faecalis isolates: implications for gut microbiota.
Rahman MU, Ilyas M, Atta A, Alioui Y, Ali S, Ullah H, Ali M, Deng T, Farooqui NA, Ma R, Abusidu M, Wang J, Wang L, Xin Y
Frontiers in nutrition 2025;12:1651499
Frontiers in nutrition 2025;12:1651499
Luteolin attenuates LPS-induced damage in IPEC-J2 cells by enhancing mitophagy via AMPK signaling pathway activation.
Yuan J, Zhang K, Yang L, Cheng X, Chen J, Guo X, Cao H, Zhang C, Xing C, Hu G, Zhuang Y
Frontiers in nutrition 2025;12:1552890
Frontiers in nutrition 2025;12:1552890
Studies on the alleviating effect of Bifidobacterium lactis V9 on dextran sodium sulfate-induced colitis in mice.
Duan X, Wu R, Li J, Li Z, Liu Y, Chen P, Wang B
Frontiers in medicine 2025;12:1496023
Frontiers in medicine 2025;12:1496023
Lignans-rich extract of Schisandra chinensis prevent alcohol-associated liver disease by regulating the gut microbiota and tryptophan metabolism.
Chi YY, Xiang JY, Li HM, Shi HY, Ning K, Xiang H, Xie Q
Current research in food science 2025;11:101172
Current research in food science 2025;11:101172
Stachyose alleviates high-fat diet-induced obesity via browning of white adipose tissue and modulation of gut microbiota.
Chen S, Li T, Zhao P, Liang P, Huang X, Song L, Wang T
Current research in food science 2025;10:101081
Current research in food science 2025;10:101081
A pectic polysaccharide from Lycium ruthenicum Murray alleviates dextran sulfate sodium-induced colitis in mice.
Dong D, Wang H, Bi H, Li Y, Gao T, Feng J, Li G, Guo S, Yuan H, Ni W
Current research in food science 2025;10:100955
Current research in food science 2025;10:100955
Benzo[a]pyrene aggravated ovalbumin‑induced epithelial tight junction disruption via ROS driven‑NLRP3/Caspase‑1 signaling pathway in asthmatic mice.
Xu Y, Feng Y, Wang L, Xu X, Xu L, Wang B
International journal of molecular medicine 2025 Sep;56(3)
International journal of molecular medicine 2025 Sep;56(3)
Nucleotide-binding domain-like receptor protein 3 inflammasome contributes to vascular endothelial barrier dysfunction and shock after burn injury.
Yu H, Lyu F, Cheng Z, Luo M, Sasmita BR, Lan Y, Lv D
Burns : journal of the International Society for Burn Injuries 2025 Sep;51(7):107589
Burns : journal of the International Society for Burn Injuries 2025 Sep;51(7):107589
A novel glucomannan from Bletilla striata ameliorates colitis: Restores intestinal barrier, alleviates inflammation, and modulates the gut flora.
Sun X, Zhang T, Zhao Y, Yang H, Li Y, Sun X, Bian X
International journal of biological macromolecules 2025 Sep;321(Pt 3):146421
International journal of biological macromolecules 2025 Sep;321(Pt 3):146421
Ovotransferrin ameliorated intestinal barrier dysfunction in DSS-induced ulcerative colitis mice via inhibition of PI3K-Akt/MAPK signaling pathways and modulation of tissue metabolism.
Zheng D, Ma L, Xin X, Gao Y, Dong S, Huang Y, Wu J, Huo J, Li S
International journal of biological macromolecules 2025 Sep;321(Pt 1):146274
International journal of biological macromolecules 2025 Sep;321(Pt 1):146274
Associations between the effectiveness of sleeve gastrectomy and the composition and function of gut microbiome in obese rats.
Cao Y, Qin S, Liu D, Zhang T, Wu Y, Xie M, Wang J
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2025 Sep;29(9):102153
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2025 Sep;29(9):102153
Protective effects of artesunate on the neurovascular unit by regulating PDGFRβ signaling in experimental cerebral malaria.
Dai Y, Zheng Z, Ma J, Liu C, Deng S, Liang Y, Liu T, Wang L, Li Y, Chen L
Biochemical pharmacology 2025 Sep;239:117023
Biochemical pharmacology 2025 Sep;239:117023
TBX21 knockdown attenuates neuroinflammation induced by intracerebral hemorrhage via the SIRT1-WDR5-H3K4me3 axis.
Zou Z, Liu Z, Zhang Z, Li X
Brain research bulletin 2025 Sep;229:111415
Brain research bulletin 2025 Sep;229:111415
TIMP1 inhibits Rac1-mediated ROS production to ameliorate blood-spinal cord barrier disruption in amyotrophic lateral sclerosis.
Tang J, Kang Y, Chen Q, Zhang B, Shang N, Lan J, Wu L, Peng Y
Neurobiology of disease 2025 Sep;213:106987
Neurobiology of disease 2025 Sep;213:106987
Active compounds of licorice ameliorate microplastics-induced intestinal damage by targeting FADD.
Xue W, Fan X, Hui Y, Yu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115570
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115570
Gut dysbiosis exacerbates inflammatory liver injury induced by environmentally relevant concentrations of nanoplastics via the gut-liver axis.
Xia S, Yan C, Cai G, Xu Q, Zou H, Gu J, Yuan Y, Liu Z, Bian J
Journal of environmental sciences (China) 2025 Sep;155:250-266
Journal of environmental sciences (China) 2025 Sep;155:250-266
Wendan Decoction exerts therapeutic effects on insomnia by regulating gut microbiota and tryptophan metabolism.
Tian Y, Meng J, Zhang D, Zhai B, Cheng J, Zou J, Shi Y, Guo D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157028
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157028
Study on the effects of the atractylodes macrocephala koidz-raphanus sativus l herb pair in alleviating senile constipation via the gut microbiota-SCFAs-5-HT axis.
Gao F, Su J, Li J, Gan C, Jin X, Zhou H, Liu X, Yu J, Yan M, Chen S, Lv G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156977
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156977
HDAC/NF-κB signaling pathway mediates gut microbiota dysbiosis in rheumatoid arthritis: Intervention mechanisms of Fengshining decoction.
Wen Y, Li M, Hao Y, Peng J, Wei X, Zhang Z, Liu B, Wang Y, Peng T, Ma Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156976
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156976
Caffeic acid improves intestinal barrier function integrity through activation of Nrf2 signaling pathway in weaned piglets and H(2)O(2) induced IPEC-J2 cells.
Zhu X, Qiao T, Huang Z, Jia G, Zhao H, Chen X
The Journal of nutritional biochemistry 2025 Sep;143:109952
The Journal of nutritional biochemistry 2025 Sep;143:109952
Neonatal necrotizing enterocolitis attenuates adult asthma via eosinophil ferroptosis.
Lai J, Zhang H, Li H, Li F, Huang D, Huang D, Zhao X, Wang Y, Jiang C, Huang R, Hao H, Wu B, Wu D
Cellular signalling 2025 Sep;133:111878
Cellular signalling 2025 Sep;133:111878
Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia-Reperfusion Injury.
Jin H, Li Z, Tan S, Xiao Q, Li Q, Ye J, Zhou Y, Wan Y, Liu Q, Menon BK, Hu B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03722
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(36):e03722
Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT.
Cai C, Zheng Y, Sun B, Wang G, Li P, Geng H, Li R, Zhu M, Zhu Y, Feng D, Chen L, Chu G, Deng L, Qiao S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e08280
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e08280
Microenvironment-driven transformable self-assembly nanoplatform enables spatiotemporal remodeling for rheumatoid arthritis therapy.
Hu C, Ma J, Chen X, Chen Y, Song Y, Tang Q, He X, Wang Y, Gao H, Zhang J
Science advances 2025 Sep 5;11(36):eadu5245
Science advances 2025 Sep 5;11(36):eadu5245
Role of Necroptosis and Neuroinflammation in CSVD-Associated Cognitive Decline in db/db Mice.
Wang DQ, Wang L, Zhao P, Gu YM, Xia XS, Li T, An N, Li X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e70868
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 30;39(18):e70868
Microbiota-mediated metabolic alterations reveal bidirectional regulation of the gut-nose axis in mice with allergic rhinitis.
Dong L, Chen T, Li F, Shen T, Wu Y, Deng Y, Tao Z
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2025 Sep 3;
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2025 Sep 3;
Salecan Suppresses Pancreatic Cancer Progression by Promoting Necroptosis via the RIPK1/MLKL Pathway.
Du W, Xu R, Chen P, Wen J, Sun L, Chen X
Nutrients 2025 Sep 28;17(19)
Nutrients 2025 Sep 28;17(19)
Protective effects of Dachengqi Decoction in sepsis-associated liver injury based on network pharmacology analysis and experimental validation.
Liu Y, Lei Y, Shang L, Yu Z, Wang L, Zhou J, Pan G
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120450
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120450
Zhutong Decoction relieves constipation by enhancing intestinal peristalsis through modulation of C-KIT/ANO1 and PDGFRα/SK3 in the SIP syncytium.
Shi L, Gao J, Liu J, Li Y, Yang H, Qu B, Chen K, Pu X, Cai S, Liu L, Feng M, Xiao H
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120330
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120330
Shenling Baizhu Powder and Betulin attenuate sepsis-induced intestinal injury by targeting GADD45B/TAOK1/p38 MAPK pathway.
Xia G, Shen C, Xiao Y, Wang X, Qiu L, Lei S, Jiang R
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120282
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120282
Ginsenoside Rk3 Alleviates Neuroinflammation and Gastrointestinal Dysfunction in Parkinson's Disease via Modulation of Gut Microbiota-Mediated Butyric Acid Metabolism.
Zhou S, Liu Y, Liu Y, Duan Z, Zhu C, Wang P, Fu R
Journal of agricultural and food chemistry 2025 Sep 24;73(38):24139-24154
Journal of agricultural and food chemistry 2025 Sep 24;73(38):24139-24154
Artesunate promotes intestinal epithelial barrier repair by facilitating HMGCS2-dependent ketogenesis in experimental ulcerative colitis model mice.
Wang G, Han L, Sun H, Sun T, Wu B, Cheng X, Yang S, Zhou D
International immunopharmacology 2025 Sep 23;162:115152
International immunopharmacology 2025 Sep 23;162:115152
Cardamonin alleviates intestinal inflammation in LPS-induced weaned piglets through the AhR/Nrf2/NLRP3 signaling pathway.
Hu X, Fang Y, Zhang Y, Deng T, Ji M, Yang W, Shi L, Xun W
International immunopharmacology 2025 Sep 23;162:115144
International immunopharmacology 2025 Sep 23;162:115144
Palmatine ameliorates intestinal epithelial barrier injury in ulcerative colitis via targeting enolase 3.
Zhang Y, Lai Z, Hu X, Wu M, Chen S, Su L, Xie S, Ren M, Yang B, Wang J, Huang W, Su Z, Li Z, Xie Y
International immunopharmacology 2025 Sep 23;162:115110
International immunopharmacology 2025 Sep 23;162:115110
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/NF-κB/MLCK/MLC signaling in ulcerative colitis.
Zhou R, Cui Y, Wang W, Qu Y, Zhang G, Wang X, Sun Y, Li J
International immunopharmacology 2025 Sep 23;162:115099
International immunopharmacology 2025 Sep 23;162:115099
Electroacupuncture suppresses motor impairments via microbiota-metabolized LPS/NLRP3 signaling in 6-OHDA induced Parkinson's disease rats.
Quan J, Liu X, Liang S, Nie L, Zhang L, Hong X, He M, Lei S, Duan L, Zhang Y, Zhuang L
International immunopharmacology 2025 Sep 23;162:115089
International immunopharmacology 2025 Sep 23;162:115089
Metal-Organic Framework-Remodeled Gut Microbiota Alleviates Colonic Inflammation via Selective Modulation of Roseburia intestinalis.
Hu H, Su X, Dong Q, Yuan S, Ding S, Liu J, Xu B, Tu L, Liu X, Cao Y, Wang X, Yang G, Guo W, Fu S, Chao D
ACS nano 2025 Sep 2;19(34):31107-31125
ACS nano 2025 Sep 2;19(34):31107-31125
Chronic Exposure to Sunset Yellow Promotes Susceptibility to Experimental Colitis in Mice through Gut Microbiota.
Shi X, Wan L, Ni S, Wu X, Mu J, Pei W, Chen Z, Xia Y, Li L, Zhang Z
Journal of agricultural and food chemistry 2025 Sep 17;73(37):23633-23643
Journal of agricultural and food chemistry 2025 Sep 17;73(37):23633-23643
Study on the mechanism of penetration of particles of air pollution into the brain through the nasal cavity and the potential neurological health risks.
Zhang Y, Zhang H, Li H, Li J, Wei H, Wang Y, Wang T, Du S, Li P
Ecotoxicology and environmental safety 2025 Sep 15;303:118963
Ecotoxicology and environmental safety 2025 Sep 15;303:118963
The Fluidic Shear Stress Loading Method Enables Mechanobiological Stimulation in an On-Chip Pump-Integrated Microphysiological System.
Yap JH, Ishizaki S, Nakamura H, Shinha K, Kimura H
Micromachines 2025 Sep 15;16(9)
Micromachines 2025 Sep 15;16(9)
Lactobacillus plantarum CCFM639 ameliorates vascular dysfunction in mice with Kawasaki disease involving eNOS/NO pathway.
Yu F, Yang T, Zhou Y, Gan T, Zhu Y, Zheng S, Zhou T, Li W, Zhou T
European journal of pharmacology 2025 Sep 15;1003:177877
European journal of pharmacology 2025 Sep 15;1003:177877
Exposure to Bovine Viral Diarrhea Virus Disrupts Intestinal Barrier Function via NLRP3/Caspase-1-Mediated Pyroptosis and Gut Microbiota Dysbiosis.
Chen S, Liu F, Han X, Jia D, Chen J, Wei Y, Yu Z, He L, Liao C, Ding K
Journal of agricultural and food chemistry 2025 Sep 10;73(36):22384-22396
Journal of agricultural and food chemistry 2025 Sep 10;73(36):22384-22396
Metformin limits cerebral cavernous malformation development by targeting KLF4-mediated mitochondrial damage.
Yan C, Ye Y, Liu N, Zhang D, Du W, Li Y, Li G, Li C, Li J, Ma S, Dai Z, Xiong Z, Wang Y, Men C, Bi R, Duan Q, Xu W, Husilengtu, Cao Y, Du J, Shi C
Biochemical and biophysical research communications 2025 Sep 1;777:152241
Biochemical and biophysical research communications 2025 Sep 1;777:152241
Polyphyllin I enhances the anti-tumor efficacy of Palbociclib by reversing M2 macrophage polarization in lung cancer.
Jiang Y, Wang L, Chen Y, Li Y, Chen G, Lu Y, Jiang C, Chai K, Wang Y
Biochemical and biophysical research communications 2025 Sep 1;777:152228
Biochemical and biophysical research communications 2025 Sep 1;777:152228
A phosphoproteomic study uncovers the importance of PP2A-B56α in liver injury precipitated by NLRP3 activation during MC-LR exposure.
Yin H, Jiang H, Zhao R, Zhang Y, Fan X, Zhai X, Yang X, Zhang Y
Ecotoxicology and environmental safety 2025 Sep 1;302:118752
Ecotoxicology and environmental safety 2025 Sep 1;302:118752
Isoquercitrin mitigates intestinal ischemia-reperfusion injury by regulating intestinal flora and inhibiting NLRP3 inflammasome activation.
Xu H, He TQ, Chen SY, Shi RR, Xu J, Xing YR, Shi D, Liu YQ, He BS, Gu JH
Redox biology 2025 Oct;86:103803
Redox biology 2025 Oct;86:103803
Dectin-1 Drives Diabetic Retinopathy via Inducing Microglia-Mediated Inflammation and Blood-Retinal Barrier Breakdown.
Zhang L, Zhang S, Li Y, Yang Z, Hu W, Bai H, Zhou W, Wang Z, Li M, Zhang S, Liao R
Developmental neurobiology 2025 Oct;85(4):e22997
Developmental neurobiology 2025 Oct;85(4):e22997
Disruption of Bile Acid Metabolism in the Gut-Liver Axis Predisposes Mice to Inflammatory Bowel Disease.
Chang H, Jiang Y, Zhao Q, Su Z, Chen M, He Q, Lai J, Jiang Y, Zheng J, Pan R, Shao J, Zhao RC, Chen Y
MedComm 2025 Oct;6(10):e70429
MedComm 2025 Oct;6(10):e70429
Overexpression of colonic VIP ameliorates cognitive function and barrier system damage caused by sevoflurane anesthesia and surgery in aged rats with fragile brain functions.
Liao H, Wang X, Yang C, Wang Z, Liu X, Liu H, Zhang J, Shen H, Wang H
Experimental neurology 2025 Oct;392:115328
Experimental neurology 2025 Oct;392:115328
Outer membrane protein A mediates Klebsiella pneumoniae penetration of the blood-brain barrier and induces bacterial meningitis.
Zeng W, Sun Y, Zhang J, Yao Z, Cao J, Hu P, Qian C, Li J, Zhou T
Microbiological research 2025 Oct;299:128262
Microbiological research 2025 Oct;299:128262
Genetical TRPV4 deletion-associated gut microbiota alleviates cardiac dysfunction in mice with diabetic cardiomyopathy.
Zhou Y, Yang T, Zheng S, Gan T, Yu F, Liu G, Zhou T
Journal of molecular and cellular cardiology 2025 Oct;207:37-50
Journal of molecular and cellular cardiology 2025 Oct;207:37-50
Structural Variations in Ulcerative Colitis-associated Escherichia coli Reduce Fructose Utilization and Aggravate Inflammation Under High-Fructose Diet.
Wu X, Li Y, Li P, Lu G, Wu J, Wang Z, Wen Q, Cui B, Wang J, Zhang F
Gastroenterology 2025 Oct;169(5):909-924
Gastroenterology 2025 Oct;169(5):909-924
Maslinic acid alleviates ulcerative colitis by inhibiting the colitis-aggravating pathogen Clostridium perfringens and modulating gut microbiota.
Geng B, Zhu C, Cui Z, Chen Y, Zhang Q, Shi H, Min L, Zhu S, Zhang W, Zhao M, Zhang S, Xu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157144
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157144
Gastrodin ameliorates DSS-induced ulcerative colitis via enhancing the abundance of Akkermansia muciniphila and modulating the metabolites.
Zhang X, Cai J, Chen L, Tai J, Liu J, Cao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157138
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157138
Endothelial Piezo1 Mediates Barrier Dysfunction and NLRP3 Inflammasomes Activation in Psoriasis.
Yue L, Pang B, Li G, Zhang C, Li Q, Li K, Fang H, Zhu Z, Shao S, Dang E, Wang G, Qiao P
The Journal of investigative dermatology 2025 Oct;145(10):2484-2494.e5
The Journal of investigative dermatology 2025 Oct;145(10):2484-2494.e5
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression.
He Z, Feng YD, Zhang YX, Gao X, Liu JJ, Liu S, Wu GQ
Cellular signalling 2025 Oct;134:111932
Cellular signalling 2025 Oct;134:111932
Nod2 deficiency exacerbates schizophrenia-related alterations in offspring of maternal immune activation in a sex-dependent manner.
Gao F, Wang C, Cao Z, Zhang X, Xi W, Liu Y, Zhan X, Jia M, Gou N, Yu L, Zhang Y, Guo Y, Wang W, Zhu F, Ma X, Gao Y
Brain, behavior, and immunity 2025 Oct;129:126-142
Brain, behavior, and immunity 2025 Oct;129:126-142
Intestinal Epithelial-Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78-mediated Endoplasmic Reticulum Stress.
Qian C, Hu C, Xu Y, Xu W, Wang Z, Gan W, Tang W, Huang L, Samorodov AV, Wang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e00741
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e00741
Polygonatum sibiricum Polysaccharides Alleviate Simulated Weightlessness-Induced Cognitive Impairment by Gut Microbiota Modulation and Suppression of NLRP3/NF-κB Pathways.
Chen F, Khan MN, Xie M, Zhang Y, Li L, Dar Farooq A, Liu J, He Q, Liu X, Jiang N
Nutrients 2025 Oct 5;17(19)
Nutrients 2025 Oct 5;17(19)
The role of ROCK1/MLC/NMMHC IIA-actin signaling in ischemic stroke-induced blood-brain barrier disruption: implications for therapeutic intervention.
Bao L, Xu Y, Ren Y, Dai Y, Yu J, Zhang M, Gong S, Kou J
Cellular and molecular life sciences : CMLS 2025 Oct 30;82(1):373
Cellular and molecular life sciences : CMLS 2025 Oct 30;82(1):373
Hyocholic Acid Species as the Key Modulator for Cecal Epithelial Homeostasis in Low-Birth-Weight Piglets.
Yin C, Liu X, Fang W, Meng Q, Feng X, Zhang W, Dang G, Zhong R, Chen L, Wang Z, Zhang H
Nutrients 2025 Oct 30;17(21)
Nutrients 2025 Oct 30;17(21)
Rosmarinic acid improves intestinal barrier integrity through PI3K/AKT/Nrf2-mediated regulation of tight junction protein expression.
Tang L, Deng J, Shi P, Zou S, Ran H, Yin F, Liu J
International immunopharmacology 2025 Oct 30;164:115380
International immunopharmacology 2025 Oct 30;164:115380
Neuronal pentraxin 1 accelerates post-stroke atherosclerosis by inducing endothelial cell senescence.
Wu Y, Luo R, Guan H, Zhang X, Yang X, Wang W, Li Q
International immunopharmacology 2025 Oct 30;164:115363
International immunopharmacology 2025 Oct 30;164:115363
Lychee Fermented by Mixed Probiotic Strains Alleviates D-Galactose-Induced Skeletal Muscle and Intestinal Aging in Mice.
Han H, Tao J, Bai X, Jing Y, Zhai Z, Luo J, Zhang W, Gan D, Hao Y
Foods (Basel, Switzerland) 2025 Oct 29;14(21)
Foods (Basel, Switzerland) 2025 Oct 29;14(21)
Green synthesized mesoporous silica nanoparticles offer a promising drug delivery system investigated in physiologically relevant 3D microfluidic models.
Porrang S, Baran G, Mustafaoglu N
RSC advances 2025 Oct 28;15(49):42071-42086
RSC advances 2025 Oct 28;15(49):42071-42086
Preventive effects of sheep milk on DSS-induced colitis in mice: modulation of gut microbiota and inflammatory responses.
Ahmad N, Zhu Z, Chu T, Jiaxin L, Danni L, Yue J, Zhang L, Yuan H, Song Y
Food & function 2025 Oct 27;16(21):8444-8462
Food & function 2025 Oct 27;16(21):8444-8462
Double-Layered Microphysiological System Made of Polyethylene Terephthalate with Trans-Epithelial Electrical Resistance Measurement Function for Uniform Detection Sensitivity.
Kutsuzawa N, Nakamura H, Chen L, Fujioka R, Mori S, Nakatani N, Yoshioka T, Kimura H
Biosensors 2025 Oct 2;15(10)
Biosensors 2025 Oct 2;15(10)
Targeting PLOD2 induces epithelioid differentiation and improves therapeutic response in sarcomatoid renal cell carcinoma.
Chen X, Xu D, Ji Y, Dong X, Dong X, Li Z, Tan J, Sun Q, Xin H, Liu Z, Deng Q, Wen T, Jia Y, Zhu X, Liu J
Journal of advanced research 2025 Oct 16;
Journal of advanced research 2025 Oct 16;
Enhancement of Intestinal Barrier Function by Butyryl-Fructooligosaccharides via Microbiota-Host Interactions in Colonic Organoid Models.
Li H, Liu L, Liu J, Zheng H, Long J, Wang J, Ku S, Weng M, Kang S
Journal of agricultural and food chemistry 2025 Oct 15;73(41):26141-26153
Journal of agricultural and food chemistry 2025 Oct 15;73(41):26141-26153
Nicotinamide mononucleotide rescues Di-n-butyl phthalate induced blood-brain barrier damage via NAD(+)/Sirt1/FOXO1a pathway activation.
Liu R, Feng J, Song Y, Yin H, Yang Z, Zhao Y, Ma J, Chen X, Gao H
Ecotoxicology and environmental safety 2025 Oct 15;305:119290
Ecotoxicology and environmental safety 2025 Oct 15;305:119290
SOCS2 alleviates traumatic brain injury-induced mitochondrial damage and parthanatos in endothelial cells by inhibiting the JAK2/STAT3 signaling pathway.
Zhang H, Gui Y, Che W, Deng S, Yang L
Metabolic brain disease 2025 Oct 14;40(7):289
Metabolic brain disease 2025 Oct 14;40(7):289
Corynebacterium striatum drives neutrophilic asthma via IL-17 signaling activation.
Yu X, Li X, Wang Y, Yu X, Guo X, Wang C, Wang F
International immunopharmacology 2025 Oct 10;163:115255
International immunopharmacology 2025 Oct 10;163:115255
Long noncoding RNA ENST00000458139 promotes mitochondrial dysfunction and apoptosis of podocytes in diabetic kidney disease through binding with SNRPA1.
Yang M, Fan X, Lang Y, Hu J, Wang Q, Shen N, Zhang D, Chai S, Wang R, Lv Z
International immunopharmacology 2025 Oct 10;163:115232
International immunopharmacology 2025 Oct 10;163:115232
Therapeutic effects of D-cycloserine in mouse models of IBD and CAC: Targeting NLRP3 inflammasome and intestinal barrier integrity.
Chen S, Yan L, Zeng J, Meng W, Zhuang J, Chen F, Guo Y, Abd El-Aty AM, Ju X, Yang S
International immunopharmacology 2025 Oct 10;163:115209
International immunopharmacology 2025 Oct 10;163:115209
Vitamin D Deficiency Exacerbates d-Galactose-Induced Intestinal Barrier Dysfunction in a Murine Model of Intestinal Aging.
Feng X, Li J, Meng Y, Jing Y, Qian H, Zhang W, Liu R, Wang D, Zhang W, Hao Y, Gan D, Shi W
Journal of agricultural and food chemistry 2025 Oct 1;73(39):24725-24740
Journal of agricultural and food chemistry 2025 Oct 1;73(39):24725-24740
Mechanism of silica nanoparticles induced pulmonary epithelial-mesenchymal transition mediated by exosomal HNRNPAB.
Zhao X, Pan Y, Yan G, Yu Y, Song Y
Ecotoxicology and environmental safety 2025 Oct 1;304:119162
Ecotoxicology and environmental safety 2025 Oct 1;304:119162
Developmental exposure to methyl ester sulfonate induces autism-like behavioral deficits in mice by dysregulation of the Notch/Hes signaling pathway disrupting neuronal differentiation.
Hu L, Ren K, Li Y, Xia Y, Chen G, Wang X, Luo C, Sun Y, Li D
Archives of toxicology 2025 Nov;99(11):4631-4647
Archives of toxicology 2025 Nov;99(11):4631-4647
OSBPL2 deficiency impaired cochlear blood-labyrinth barrier via activation of NF-κB signaling pathway.
Yang Q, Li T, Lu Y, Wang T, Chen Z, Xing G, Wei Q, Cao X, Yao J
Hearing research 2025 Nov;467:109432
Hearing research 2025 Nov;467:109432
Electroacupuncture at Baliao Points Attenuates Visceral Hypersensitivity in Irritable Bowel Syndrome via Gut-Microbiota-Mast Cell-TPRV1 Axis Modulation.
Sun MY, Xing HH, Lin X, Hong-haoWu, Cheng BG, Liu X, Ni M
Neurogastroenterology and motility 2025 Nov;37(11):e70137
Neurogastroenterology and motility 2025 Nov;37(11):e70137
Regulatory effects of Ophiopogon japonicus polysaccharide on intestinal immune function in mice.
Lin F, Yu L, Lu X, Yu Y, He J, Mao N, Shi X, Wang D
International journal of biological macromolecules 2025 Nov;330(Pt 4):148339
International journal of biological macromolecules 2025 Nov;330(Pt 4):148339
Oral absorption mechanisms of Astragalus polysaccharides and potential as an excipient to increase the absorption of flavonoids.
Wu X, Xu Y, Zhu D, Zhang W, Yang Y, Feng L, Yang B, Jia X
International journal of biological macromolecules 2025 Nov;330(Pt 2):147977
International journal of biological macromolecules 2025 Nov;330(Pt 2):147977
A High-Fat Diet Damages the Blood-Testis Barrier Through the PCSK9-LOX1 Positive Feedback Loop in Sertoli Cells.
Zhang G, Wang Z, He M, Kong L, Yushanjiang S, Jin L, Zhao R, Ma Z, Pan Y, Hu Y, Nie L, Yuan D
Reproductive sciences (Thousand Oaks, Calif.) 2025 Nov;32(11):3587-3598
Reproductive sciences (Thousand Oaks, Calif.) 2025 Nov;32(11):3587-3598
The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs.
Wang W, Wu H, Li J, Chen Z, Liu J, Xu E, Hassanin AA, Rahman SU, Chen L, Zheng R
Protoplasma 2025 Nov;262(6):1451-1468
Protoplasma 2025 Nov;262(6):1451-1468
Silymarin ameliorates diet-induced gallstone formation by regulating gut microbiota-derived GCDCA to suppress ferroptosis-ROS-NFκB signaling pathway.
Wang Q, Han C, Zheng Y, Liu X, Lv Z, Du Z, Liu T, Hao C, Meng X, Li T, Xue D
Free radical biology & medicine 2025 Nov;239:496-512
Free radical biology & medicine 2025 Nov;239:496-512
Macrophage NADPH oxidase inhibition by ultralow-dose dextromethorphan alleviates DSS-induced inflammation and colitis.
Li Y, Hou L, Cheng K, He G, Hong JS, Li S, Zhao J, Guo Y
Free radical biology & medicine 2025 Nov;239:189-201
Free radical biology & medicine 2025 Nov;239:189-201
Neutrophil extravasation and NETosis in decompression illness lung injury: A P-selectin/PSGL-1/NOX2/PAD4 axis governed pathway validated by multi-model interrogation.
Li Z, Wang S, Bai Y, Liu S, Huang J, You Y, Li J, Yu X, Han Y, Bao X
Free radical biology & medicine 2025 Nov;239:14-26
Free radical biology & medicine 2025 Nov;239:14-26
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation.
Cardona-Benavides IJ, Cristobal-Vargas S, De Ramón C, Rojas EA, Misiewicz-Krzeminska I, Isidro I, Pérez JJ, Paiva B, Puig N, Alcoceba M, Mateos MV, Corchete LA, Cuadrado M, Gutiérrez NC
Molecular oncology 2025 Nov;19(11):3175-3192
Molecular oncology 2025 Nov;19(11):3175-3192
A novel off-liver sinusoidal progenitor cells in supporting transplantable bioliver engineering.
Lai J, Hu D, Yan M, Chen Q, Shi H, Yang Q, Ding M, Li L, Zhang H, Bai L
Biomaterials advances 2025 Nov;176:214358
Biomaterials advances 2025 Nov;176:214358
Vitamin D3 Improves Hypothalamic-Pituitary-Adrenal Axis Function, Immunological Responses, and Gut Dysbiosis in Sleep Desynchrony.
Wu CW, Huang YJ, Xu JW, Fan HY, Zeng JL, Yang YSH, Tung YT
Brain and behavior 2025 Nov;15(11):e71084
Brain and behavior 2025 Nov;15(11):e71084
Fufang Huangqi Jianpi Oral Liquid alleviates spleen deficiency diarrhea via modulation of the NF-κB/Nrf2 signaling pathway and apoptosis.
Huang L, Qiu Z, Sun K, Yu C, Huang Q, Liu C, Pan X, Li S, Ge S, Shi X, Hu F, Xin R
3 Biotech 2025 Nov;15(11):377
3 Biotech 2025 Nov;15(11):377
Gut microbiota-bile acid metabolic disorder involved in the cognitive impairments in epilepsy through HO-1 dependent ferroptosis.
Li X, Ji J, Li J, Li S, Luo Q, Gu M, Yin X, Zhang M, Fan H, Yao R
Journal of pharmaceutical analysis 2025 Nov;15(11):101291
Journal of pharmaceutical analysis 2025 Nov;15(11):101291
Yuzhi Zhixue Granules regulate the JAK/STAT pathway to affect T-cell differentiation in the colon of ulcerative colitis.
Zhang Y, He C, Zhao Y, Jiang M, Yao J, Cheng G, Niu D, Zeng Z, Dai E, Liu R, Shang G, Qu X, Kong H, Zhang Y, Qu H, Zhao Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157198
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157198
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Tao X, Gao Y, Jin Z, Lu S, Li Z, Guo S, Fan Q, Li J, Qiao C, Lei H, Zhang Z, Zhao C, Wu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Obacunone ameliorates high-fat diet-induced MAFLD by regulating the PPARγ-FABP1/CD36 axis and the gut-liver crosstalk.
Wang X, Hong J, Liang R, Bao S, Li L, Wang J, Feng J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157180
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157180
Huaier overcomes tumor-induced immunosuppression in colorectal cancer by activating MHC I and CD8+ T cells.
Chen J, Li Y, Sun Q, Wang Y, Qiu Z, He X, Zhong X, Chen F, Huang H, Chen K, Zhu Y, Yao Y, Hu Z, Wang X, Tang J, Zhao S, Wei P, Li D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157157
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157157
Benzoylpaeoniflorin alleviates ulcerative colitis by inhibiting ferroptosis through targeting phosphogluconic dehydrogenase.
Tang Y, Wang Z, Zhou F, Li L, Sun C, Li L, Tang F, Huang D, Li Z, Tan Y, Pei G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157111
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157111
MicroRNA-93-5p alleviates uric acid-induced fibrosis in renal tubular epithelial cells by regulating the SMAD5/Id2 signaling pathway.
Lu X, Ma C, Li D, Yang J, Sun Y, Liu B, Zhao B, Li H
Cellular signalling 2025 Nov;135:112081
Cellular signalling 2025 Nov;135:112081
Bavachinin alleviates allergic rhinitis by modulating gut microbiota and inhibiting NLRP3-mediated epithelial pyroptosis through PI3K/AKT/NF-κB signaling pathway.
Chen T, Dong L, Wu Y, Shen T, Deng Y, Li F, Tao Z
Cellular signalling 2025 Nov;135:112026
Cellular signalling 2025 Nov;135:112026
Octanoic Acid-Rich Enteral Nutrition Regulates Intestinal M1/M2 Macrophage Polarization via the PPARγ/STAT-1/STAT-6 Pathway to Alleviate Inflammatory Bowel Disease.
Xue L, Cao C
Food science & nutrition 2025 Nov;13(11):e71234
Food science & nutrition 2025 Nov;13(11):e71234
Megasphaera Elesdenii Dysregulates Colon Epithelial Homeostasis, Aggravates Colitis-Associated Tumorigenesis.
Hou X, Zhang Z, Chen W, Li J, Zhu X, Li M, Guan X, Guo H, Ma Y, Zhao L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e05670
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e05670
Effect of berberine on LPS-induced intestinal epithelial injury and m(6)A methylation in broilers.
Yuan L, Li W, Li G, Jin W, Wang B, Li S, Wang H
Poultry science 2025 Nov;104(11):105677
Poultry science 2025 Nov;104(11):105677
Pgk1 activation restores endothelial metabolic homeostasis to alleviate vascular aging and atherosclerosis.
Lu J, Wang J, Liu Y, Zhang C, Zhang G, Ge Y, Liu L
Cardiovascular diabetology 2025 Nov 8;24(1):427
Cardiovascular diabetology 2025 Nov 8;24(1):427
Phosphorylation of EF-P aggravates Streptococcus suis-induced blood-brain barrier damage by enhancing serine protease production.
Yin H, Tian Y, Zhou Z, Lang S, Li Y, Peng L, Li J, Fang R
Veterinary research 2025 Nov 7;56(1):215
Veterinary research 2025 Nov 7;56(1):215
Streptozotocin Causes Blood-Brain Barrier and Astrocytic Dysfunction In Vitro.
Habib SA, Kamal MM, Aly MH, Ghaiad HR, Rizk SM, Banks WA, Erickson MA
Cells 2025 Nov 6;14(21)
Cells 2025 Nov 6;14(21)
Atorvastatin improves spermatogenesis in murine and in vitro human chronic orchitis models through restoring blood-testis barriers.
Ma L, Chen J, Li Q, Zhu Y, Ren S, Song K, Yao Z, Yang X, Zheng Y, Liu Z, Wang Z, Miao K, Chen S, Zhao XY, Luo F
Cell death discovery 2025 Nov 6;11(1):505
Cell death discovery 2025 Nov 6;11(1):505
Unveiling the gut-vascular connection: Gut microbiota regulates cardiovascular toxicity induced by combined exposure to PM(2.5) and high-fat diet via butyric acid/NLRP3 pathway.
Tian J, Cheng J, Yang H, Niu Z, Zhao L, Guan L, Liu N, Rong S, Wang C, Shi D, Zheng H, Cao N, Li R, Zhang Y, Ren C, Zhang Z
Journal of hazardous materials 2025 Nov 5;499:140334
Journal of hazardous materials 2025 Nov 5;499:140334
Dexmedetomidine enhances anastomotic healing partly via the Wnt/β-catenin pathway in a rat model of colon surgery.
Chen Y, Li CT, Wang JB, Tang WL, Zhao Y, Chen Y, Liao LM, Zhang LC, Lin TH, Cao ZF
World journal of gastroenterology 2025 Nov 28;31(44):112833
World journal of gastroenterology 2025 Nov 28;31(44):112833
Bifidobacterium animalis subsp. lactis GOLDGUT-BB69 Counteracts Diarrhea in Mice by Alleviating Inflammation, Enhancing Intestinal Barrier Functions, and Regulating Intestinal Microbiota.
Zhao M, Li C, Fang Z, Yi Q, Ke X, Luo X, Zhou L, Wang Q
Probiotics and antimicrobial proteins 2025 Nov 28;
Probiotics and antimicrobial proteins 2025 Nov 28;
Er Miao San Attenuates Collagen-Induced Arthritis Mice by Regulating Gut Microbiota and Its Metabolites.
Xu S, Su W, Qin Z, Xuan Z, Wang J, Wang J, Tang R, Yin J, Liang J, Jia X
Journal of microbiology and biotechnology 2025 Nov 26;35:e2507054
Journal of microbiology and biotechnology 2025 Nov 26;35:e2507054
Loss of alpha-kinase 1 contributes to the formation of congenital cataracts in mice.
Wang HS, Yang YX, Duan SS, Long FY, Wu T, Yan NH, Li XH, Du JR
Cellular & molecular biology letters 2025 Nov 26;31(1):1
Cellular & molecular biology letters 2025 Nov 26;31(1):1
FABP3 Mediates Lipid Droplet Accumulation and Adhesive Capacity in Bovine Endometrial Epithelial Cells via PGE(2)/PTGER4/PPAR Axis.
Zhang B, Yan Y, Cheng M, Guo T, Gao K, Wang A, Lin P, Zhou D, Jin Y
Animals : an open access journal from MDPI 2025 Nov 26;15(23)
Animals : an open access journal from MDPI 2025 Nov 26;15(23)
Methylene blue reduces postoperative delirium in mice through neuroinflammation suppression and blood-brain barrier repair.
Deng Y, Hua J, Pan H, Zhang J
Scientific reports 2025 Nov 26;15(1):42201
Scientific reports 2025 Nov 26;15(1):42201
Huang-Lian-Jie-Du decoction alleviates diabetic ischemic stroke by modulating gut microbiota-derived short-chain fatty acids.
Chen C, Luo WH, Li A, Wu HZ, Chen DY, Chen JX, Wang ZQ, Wang SM, Tang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157476
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157476
Tongxie Yaofang attenuates ulcerative colitis by modulating gut microbiota and IL-10RA/NF-κB-mediated macrophage polarization.
Shang Z, Zhou L, Liu Y, Yang X, Yao D, Zhai F, Liu B, Chen Y, Zhu X, Liu D, Yi B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157459
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157459
Zexieyin formula attenuates Alzheimer's disease via suppressing A1 astrocyte activation: A serum pharmacochemistry and network pharmacology study.
Zhou S, Sun M, Song Z, Qin Z, Wu H, Wang M, Zhu B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157375
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157375
Oxymatrine ameliorates ulcerative colitis via improving epithelial barrier function through targeting DSG2.
Li P, Jin X, Li Y, Shen Y, Wu J, Kang N, Feng X, Qiu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157370
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157370
Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by attenuating the malignancy of cancer stem cells via the gut microbiota-bile acid-FXR axis.
Zhang Y, Shen M, Baokan J, Xu L, Ni M, Jin J, Shen W, Sun D, Li L, Lai Y, Yan Q, Yu C, Tan J, Xu C, Tao L, Fan M, Cheng H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157366
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157366
Xinqingning tablet attenuates ischemic stroke complicated by gut dysbiosis through regulating the miR-126-driven gut-brain axis.
Gong S, Xu Y, Zhao R, Yu J, Bao L, Zhang Y, Li F, Jiao L, Kou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157356
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157356
Genkwanin reduces airway epithelial cell ferroptosis and alleviates asthma symptoms in mice.
Chen X, Liu J, An Z, Li M, Ji X, Huang J, Yan X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157306
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157306
Farrerol alleviates microbiota dysbiosis-associated osteoporosis in IBD by inhibiting PI3K-AKT/MAPK signaling pathways.
Yin N, Su Y, Wang C, Liang J, Guo T, Zhao J, Ling Z, Xu R, Liu Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157279
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157279
PD-L1(+) neutrophils trigger pulmonary endothelial pyroptosis via an oxidative phosphorylation-dependent mechanism in sepsis.
Ma C, Wang L, Wang X, Zhu X, Chen Y
Respiratory research 2025 Nov 24;26(1):327
Respiratory research 2025 Nov 24;26(1):327
Activation of the aryl hydrocarbon receptor relieves acute pancreatitis via the RBX1/HSF1 pathway.
Fang Y, Zhang C, Yu J, Shen X
Journal of inflammation (London, England) 2025 Nov 22;22(1):54
Journal of inflammation (London, England) 2025 Nov 22;22(1):54
Gut Microbiota-Targeted Photobiomodulation Ameliorates Alzheimer's Pathology via the Gut-Brain Axis: Comparable Efficacy to Transcranial Irradiation.
Cao S, Shi X, Chen Y, Liu T, Hu J, Dong X, Chen H, Dai J, Yin H
Microorganisms 2025 Nov 22;13(12)
Microorganisms 2025 Nov 22;13(12)
Fatty Acid-binding Protein 4 Exacerbates Blood-brain Barrier Disruption Through the JNK/c-Jun/MMP12 Pathway After Traumatic Brain Injury.
Ma B, Yang D, Tian M, Dai S, Jing Z, He X, Bao X, Long Y, Gong Y, Dong Y, Li J, Zhang G, Cheng H, Yu J, Wang X, An Y, Wu Y
Molecular neurobiology 2025 Nov 21;63(1):130
Molecular neurobiology 2025 Nov 21;63(1):130
Autism-Associated Gut Microbiota-Derived Enterococcus facium Modulates Gut-Brain Axis Function and Behavior in Mice.
Ma R, Ullah H, Bohlooli FS, Wen Y, Xin Y, Wang J, Lu S, Wang L
Pathogens (Basel, Switzerland) 2025 Nov 21;14(12)
Pathogens (Basel, Switzerland) 2025 Nov 21;14(12)
Downregulation of oar-miR-125b Drives Blood-Brain Barrier Breakdown Through the TNFSF4-NF-κB Inflammatory Axis in Enterococcus Faecalis Meningitis.
Jiao L, Wu Y, Qi B, Zhao P, Zhou M, Zhang R, Li Y, Ren J, Cao S, Qi Y
Microorganisms 2025 Nov 21;13(12)
Microorganisms 2025 Nov 21;13(12)
Curcumin Alleviates Bisphenol A-Induced Blood-Testis Barrier Disruption in Mice by Targeting Surfactant Protein B (SFTPB) to Suppress Oxidative Stress-Activated NLRP3 Inflammasome.
Duan H, Yang S, Xiao L, Yang S, Jiang B, Fang Z, Yan Z, Zeng J, Ma X, Dong W, Liu Y
Journal of agricultural and food chemistry 2025 Nov 19;73(46):29874-29885
Journal of agricultural and food chemistry 2025 Nov 19;73(46):29874-29885
Engineering Escherichia coli nissle 1917 with lactonase ZHD101 alleviates zearalenone-induced intestinal disruption and reproductive toxicity in rat.
Dai M, Liu S, Cai R, Li D, Wen Y, Jiang J, Hao N, Wang Q, Gao X
World journal of microbiology & biotechnology 2025 Nov 19;41(12):463
World journal of microbiology & biotechnology 2025 Nov 19;41(12):463
Migration of CD8 + TSCM cells into intestine via PPBP-CXCR2 axis increases host stress susceptibility by inhibiting gut microbiome-derived homovanillic acid.
Zhang Y, Ju M, Chen S, Yang W, Cai Y, Yu X, Chen G, Shen Z, Bai Y, Ren H, Li Y, Shen L, Li J, Shi P, Yuan Y, Han B, Yao H
Nature communications 2025 Nov 19;16(1):10165
Nature communications 2025 Nov 19;16(1):10165
Dysregulated ITGA3/FAK/YAP axis mediates impaired alveolar type II epithelial cells function in COPD.
Liu L, Zhong S, Zhou T, Wu Y, Hu W, Wang X, Ren Y, Wang K, Lin X, Zhang J
Journal of advanced research 2025 Nov 19;
Journal of advanced research 2025 Nov 19;
Human umbilical cord mesenchymal stromal cell-derived exosomes alleviate antibiotic-induced intestinal barrier damage by regulating autophagy via the S100G/mTOR signaling pathway.
Guo Y, Li Y, Shi M, Li Y, Qiang J, Li J, Gao H, Zhu G, Xie B, Guo X, He B, Zhang B, Liu B
Cellular & molecular biology letters 2025 Nov 17;30(1):139
Cellular & molecular biology letters 2025 Nov 17;30(1):139
Fusobacterium nucleatum-derived extracellular vesicles carrying virulence factor DNA trigger AIM2 inflammasome activation to facilitate UC progression.
Zhao Y, Wu R, Duan Y, Kong X, Zhang Y, You Y, Zhang J, Wang Y, Zhou L, Duan L
Cellular & molecular biology letters 2025 Nov 17;30(1):138
Cellular & molecular biology letters 2025 Nov 17;30(1):138
Berberine ameliorates high-fat diet-induced metabolic disorders through promoting gut Akkermansia and modulating bile acid metabolism.
Hang WJ, Yin R, Kang XW, He L, Cao X, Chen J
Chinese medicine 2025 Nov 17;20(1):190
Chinese medicine 2025 Nov 17;20(1):190
Thymosin β4 released by mast cells under stress conditions impairs intestinal epithelial barrier via IL22RA1/JAK1/STAT3 signaling in irritable bowel syndrome.
Sun YS, Bai XQ, Sun KD, Li J, Liu L, Chen YY, Zeng ZY, Wang Q, Guo YB
World journal of gastroenterology 2025 Nov 14;31(42):111706
World journal of gastroenterology 2025 Nov 14;31(42):111706
Alterations in Gut Microbiota and their Association with Colonic Permeability and Inflammation in LPS-induced Sepsis Mice.
Zhang M, Shu Y, Yang J, Sang S, Liu X, Li Y, Qin C, An L, Lin X
Current microbiology 2025 Nov 12;83(1):15
Current microbiology 2025 Nov 12;83(1):15
Disulfiram Prevents Blood-Brain Barrier Disruption in Epileptic Mice by Inhibiting Astrocyte Pyroptosis to Improve Seizure Activity.
Zhang M, Zhao L, Chen S, Huang W, Jin X, Xu H
Molecular neurobiology 2025 Nov 12;63(1):34
Molecular neurobiology 2025 Nov 12;63(1):34
Tetrandrine enhances cognition in SAH rats via gut microbiota CYP51 and TLR4 signaling.
Liu H, Zou Q, Xiang T, Zhu R, Chen Z, Chen R
Scientific reports 2025 Nov 11;15(1):39418
Scientific reports 2025 Nov 11;15(1):39418
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Li H, Tao D, Chen Y, Deng Y, Wei W, Xue X
European journal of medical research 2025 Nov 10;30(1):1096
European journal of medical research 2025 Nov 10;30(1):1096
Folate Attenuates Ulcerative Colitis via PI3K/AKT/NF-κB/MLCK Axis Inhibition to Restore Intestinal Barrier Integrity.
Zhang S, Cheng T, Chen Y, Wang M, Wang G, Aa J
Biology 2025 Nov 10;14(11)
Biology 2025 Nov 10;14(11)
Integrated multi-omics of gut-liver axis to dissect the mechanism underlying hepatotoxicity induced by sub-chronic tire wear particles exposure in mice.
Zhou Y, Cheng P, Ran J, Li X, Yan X, Luo L, Xie M, Tian K
Ecotoxicology and environmental safety 2025 Nov 1;306:119350
Ecotoxicology and environmental safety 2025 Nov 1;306:119350
Hydroxysafflor yellow A attenuates the blood-brain barrier dysfunction and neuroinflammation through anti-inflammatory microglial polarization after intracerebral hemorrhage.
Zheng F, Guo X, Yan Q, Zhou Y, Hu E, Zhu H, Cheng M, Yu Z, Hu M, Ding R, Li H, Zhang W, Tang T, Wang Y, Li T, Deng C
Neuropharmacology 2025 Nov 1;278:110576
Neuropharmacology 2025 Nov 1;278:110576
Neuroprotective effects of urolithin a in a mouse model of intracerebral hemorrhage.
Guo Y, Zhang X, Deng J, Su Q, Liu Y, Yan G, Xue S, Yong VW, Xue M
Neuropharmacology 2025 Nov 1;278:110538
Neuropharmacology 2025 Nov 1;278:110538
Large-scale multi-trait genome-wide analysis for inflammatory bowel disease reveals new insights into its molecular mechanisms and emphasizes the roles of systemic immune regulation.
Zhu Z, Shi L, Li H, Wang X, Gao J, Cheng L, Zhang X
Briefings in bioinformatics 2025 Nov 1;26(6)
Briefings in bioinformatics 2025 Nov 1;26(6)
Gut flora-derived succinate exacerbates Allergic Airway Inflammation by promoting protein succinylation.
Wang C, Yu X, Yu X, Xiao H, Song Y, Wang X, Zheng H, Chen K, An Y, Zhou Z, Guo X, Wang F
Redox biology 2025 May;82:103623
Redox biology 2025 May;82:103623
HIF-1α Enhances Intestinal Injury and Inflammation in Severe Acute Pancreatitis Through NLRP3 Inflammasome Activation.
Gao T, Zhang H, Xu Y, He G, Ma H, Zheng C, Li L, Cheng F, Dou H, Zhang F, Zhao H, Qiu Z
Digestive diseases and sciences 2025 May;70(5):1813-1823
Digestive diseases and sciences 2025 May;70(5):1813-1823
Effects of Narrowband Ultraviolet B Therapy on the Skin Barrier in a Murine Model of Dry Skin.
Toyama S, Kamata Y, Kamo A, Tominaga M, Takamori K
Photodermatology, photoimmunology & photomedicine 2025 May;41(3):e70016
Photodermatology, photoimmunology & photomedicine 2025 May;41(3):e70016
Forsythiaside A Alleviates Ulcerative Colitis and Inhibits Neutrophil Extracellular Traps Formation in the Mice.
Wang Z, Yan W, Lin X, Qin G, Li K, Jiang L, Li X, Xiao X, Luo T, Hou Y
Phytotherapy research : PTR 2025 May;39(5):2165-2179
Phytotherapy research : PTR 2025 May;39(5):2165-2179
Gastrodin Ameliorates Tau Pathology and BBB Dysfunction in 3xTg-AD Transgenic Mice by Regulating the ADRA1/NF-κB/NLRP3 Pathway to Reduce Neuroinflammation.
Li B, Wang L, Xiao Y, Wang Y, Wang Y, Peng Y, Zhang A, Tang Z, Qi X
Phytotherapy research : PTR 2025 May;39(5):1996-2016
Phytotherapy research : PTR 2025 May;39(5):1996-2016
Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy.
Jia Y, Xu L, Leng S, Sun Y, Huang X, Wang Y, Ren H, Li G, Bai Y, Zhang Z, Han B, Shen L, Ju M, Chen L, Yao H
Advanced materials (Deerfield Beach, Fla.) 2025 May;37(19):e2500598
Advanced materials (Deerfield Beach, Fla.) 2025 May;37(19):e2500598
Dietary supplementation of yeast polysaccharides enhance lamb growth performance by improving immune and intestinal barrier function and the abundance of cecal microbiota.
Li X, Meng M, Shi H, Zhou S, Ma N, Shen X
International journal of biological macromolecules 2025 May;309(Pt 2):142849
International journal of biological macromolecules 2025 May;309(Pt 2):142849
Larimichthys crocea isinglass polysaccharide attenuates DSS-induced colitis via gut microbiota regulation and NF-κB signaling inhibition.
Sui D, Li M, Ai C, Li S, Chang H, Li Y, Zhao S, Li H, Ren X
International journal of biological macromolecules 2025 May;307(Pt 3):142263
International journal of biological macromolecules 2025 May;307(Pt 3):142263
Kai-Xin-San polysaccharides exert therapeutic effects on D-gal and Aβ(25)(-)(35)-induced AD rats by regulating gut microbiota and metabolic profile.
Cai Z, Zhang M, Zhou L, Xiong Y, Wang H, Chen Y, Yuan J
International journal of biological macromolecules 2025 May;306(Pt 4):141850
International journal of biological macromolecules 2025 May;306(Pt 4):141850
β-1,3-glucans from Euglena Gracilis protects against ulcerative colitis via modulating the gut barrier, T-cell immunity and gut microbiota.
Guo B, Zhang W, Zou J, Sun L, Dong N, Liu B
International journal of biological macromolecules 2025 May;305(Pt 2):141288
International journal of biological macromolecules 2025 May;305(Pt 2):141288
The ferroptosis of sertoli cells inducing blood-testis barrier damage is produced by oxidative stress in cryptorchidism.
Zeng J, Yuan L, Chen G, Qi Y, Qie X, Jin Y, Chen Y, Li H
Free radical biology & medicine 2025 May;232:97-106
Free radical biology & medicine 2025 May;232:97-106
Synergistic effects of the Aβ/fibrinogen complex on synaptotoxicity, neuroinflammation, and blood-brain barrier damage in Alzheimer's disease models.
Simões-Pires EN, Torrente D, Singh P, Strickland S, Norris EH
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 May;21(5):e70119
Alzheimer's & dementia : the journal of the Alzheimer's Association 2025 May;21(5):e70119
Kaempferol promotes angiogenesis through HIF-1α/VEGF-A/Notch1 pathway in ischemic stroke rats.
Zhang S, Liu C, Li W, Zhang Y, Yang Y, Yang H, Zhao Z, Xu F, Cao W, Li X, Wang J, Kong L, Du G
Neurochemistry international 2025 May;185:105953
Neurochemistry international 2025 May;185:105953
IL-33 facilitates endoplasmic reticulum stress and pyroptosis in LPS-stimulated ARDS model in vitro.
Li PL, Fu HM, Liu K, Liu HF, Sui MZ, Yang JW
Molecular immunology 2025 May;181:102-112
Molecular immunology 2025 May;181:102-112
Puerarin improves MASLD by remodeling intestinal microenvironment to promote mitochondrial fusion and autophagy.
Sun C, Du M, Sha S, Wang S, Li L, Hou J, Li L, Yuan J, Yan J, Yang Z
Journal of pharmacological sciences 2025 May;158(1):27-41
Journal of pharmacological sciences 2025 May;158(1):27-41
Odd-Chain Fatty Acid-Enriched Fats Improve Growth and Intestinal Morphology and Function in Milk Replacer-Fed Piglets.
Duan G, Li M, Zheng C, Wan M, Yu J, Cao B, Yin Y, Duan Y, Cong F
The Journal of nutrition 2025 May;155(5):1298-1310
The Journal of nutrition 2025 May;155(5):1298-1310
Three-Dimensional Dynamic Blood-Brain Barrier Model Incorporating Native Cell Culture Systems Based on Shape Memory Biomaterials.
Ta W, Wang J, Zheng A, Jia Y, Liu J, Lu W, Zhang J
Advanced healthcare materials 2025 May;14(12):e2500066
Advanced healthcare materials 2025 May;14(12):e2500066
A perfused iPSC-derived proximal tubule model for predicting drug-induced kidney injury.
Lechtenberg M, Chéneau C, Riquin K, Koenig L, Mota C, Halary F, Dehne EM
Toxicology in vitro : an international journal published in association with BIBRA 2025 May;105:106038
Toxicology in vitro : an international journal published in association with BIBRA 2025 May;105:106038
Compound probiotics alleviate hyperuricemia-induced renal injury via restoring gut microbiota and metabolism.
Liu P, Hu P, Jin M, Sun W, Wu J, Tang Y, Shi D, Xie T, Tong Y, Huang L, Zhang D, Zheng H, Xu X, He H
BMC microbiology 2025 May 8;25(1):280
BMC microbiology 2025 May 8;25(1):280
Heterophyllin B alleviates cognitive disorders in APP/PS1 model mice via the spleen-gut microbiota-brain axis.
Jiang J, Deng J, Zhao Y, Zhao S, Niazi NUK, Ge Y, Yang Z
International immunopharmacology 2025 May 8;154:114591
International immunopharmacology 2025 May 8;154:114591
Chestnut Nonstarch Polysaccharides Enhance Intestinal Barrier Integrity and Modulate Gut Microbiota to Ameliorate DSS-Induced Colitis in Mice.
Chen Y, Fang H, Wang L, Yu W, Sang Y, Wang X
Journal of agricultural and food chemistry 2025 May 7;73(18):11041-11055
Journal of agricultural and food chemistry 2025 May 7;73(18):11041-11055
Drinking Water Temperature Impacts the Pathogenesis of DSS-Induced Ulcerative Colitis by Regulating Intestinal Barrier Function and Remodeling the Gut Microbiota Composition.
Wang H, Yang Y, Li T, Chang S, Zhu Y, Liu C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70645
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70645
Insulin/PHMB-grafted sodium alginate hydrogels improve infected wound healing by antibacterial-prompted macrophage inflammatory regulation.
Liu D, Yu T, Ma S, Su L, Zhong S, Wang W, Liu Y, Yu JA, Gao M, Chen Y, Xu H, Liu Y
Journal of nanobiotechnology 2025 May 3;23(1):328
Journal of nanobiotechnology 2025 May 3;23(1):328
In vivo keratotomy by mid-infrared femtosecond laser resonant with amide vibrational mode.
Guo J, Chen P, Xiang M, Tian K, Wan Z, He L, Li W, Peng X, Peng Y, Wen X, Liu L, Wang QJ, Leng Y, Liang H
Communications medicine 2025 May 29;5(1):207
Communications medicine 2025 May 29;5(1):207
Uncovering the molecular mechanisms of tonifying kidney and activating blood Decoction against myocardial fibrosis using network Pharmacology and experimental validation.
Xu R, Bi Y, Ju Y, Yin W, Zhao S, Zhang Y, Zhao X
Scientific reports 2025 May 29;15(1):18912
Scientific reports 2025 May 29;15(1):18912
Atractylenolide-1 Alleviates Ulcerative Colitis via Restraining RhoA/ROCK/MLC Pathway-Mediated Intestinal Barrier Dysfunction.
Gao Z, Yu X, Su W, Huang P, Li Z, Lin Y, Chen LL, Cao Y, Liu Y, Chen J, Yang D, Cao G
Journal of agricultural and food chemistry 2025 May 28;73(21):12690-12701
Journal of agricultural and food chemistry 2025 May 28;73(21):12690-12701
Network-based pharmacological and experimentally validated study on the therapeutic effects and mechanisms of Polygonatum Rhizoma Ginseng Formula in immunocompromised mice.
He X, Xu W, Li L, Jiang X, Dong Y, Liu K, Feng X, Su J, Li B, Lv G, Chen S
Journal of ethnopharmacology 2025 May 28;348:119821
Journal of ethnopharmacology 2025 May 28;348:119821
Schisandra chinensis lignans ameliorate hepatic inflammation and steatosis in methionine choline-deficient diet-fed mice by modulating the gut-liver axis.
Yan LS, Kang JY, Gu CY, Qiu XY, Li JJ, Cheng BC, Wang YW, Luo G, Zhang Y
Journal of ethnopharmacology 2025 May 28;348:119801
Journal of ethnopharmacology 2025 May 28;348:119801
Potential mechanisms by which Jiawei Lianpu Yin inhibits Helicobacter pylori colonization and alleviates gastric mucosal inflammation and damage: Integrated transcriptomics, network pharmacology, and experimental validation.
Zhang X, Wang L, Huang L, Cao G, Huang C, Duan Y, Lyu W
Journal of ethnopharmacology 2025 May 28;348:119793
Journal of ethnopharmacology 2025 May 28;348:119793
Semaglultide targets Spp1(+) microglia/macrophage to attenuate neuroinflammation following perioperative stroke.
Li Y, Fan Q, Pang R, Cai L, Qi J, Chen W, Zhang Y, Chen C, Yu W, Li P
Journal of neuroinflammation 2025 May 27;22(1):143
Journal of neuroinflammation 2025 May 27;22(1):143
ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity.
Zhou S, Hua S, Chen X, Ni M, Liu J, Wang Y, Wu W, Ding A, Qin Z, Yang X, Chen X, Zhu B, Wu H
Chinese medicine 2025 May 25;20(1):68
Chinese medicine 2025 May 25;20(1):68
Pre-ischaemic empagliflozin treatment attenuates blood-brain barrier disruption via β-catenin mediated protection of cerebral endothelial cells.
Liu G, Qiu Y, You N, Yu M, Chen W, Sun T, Qin Z, Han M, Xue Z, Liang X, Mao B, Ling L, Wu Y, Xing W, Liu Q, Wang D
Cardiovascular research 2025 May 23;121(5):788-802
Cardiovascular research 2025 May 23;121(5):788-802
Probiotics may not adhere to gut and provide benefits in inflammatory bowel disease patients based on an AOM/DSS murine model.
Hu ML, Wang FS, Lian WS, Yang CH, Yang JW, Chen IY, Huang CH, Liou JS, Yang MY
Journal of the Formosan Medical Association = Taiwan yi zhi 2025 May 19;
Journal of the Formosan Medical Association = Taiwan yi zhi 2025 May 19;
NUDT1 aggravates intestinal epithelial barrier injury through oxidative stress in ulcerative colitis.
Jin G, Gao X, Dai F, Zhang H, Lu T, Jing D, Yang Y, Zhu F, Zhou G
International immunopharmacology 2025 May 16;155:114634
International immunopharmacology 2025 May 16;155:114634
IL-17 enhanced the susceptibility to fluoxetine resistance in depression via the JAK1-STAT6 signaling pathway.
Zhang M, Hong Y, Yu W, Zhang Y, Shen Y, Cai Z, Jia R, Pang Z, Huang X, Huang Y, Gao X, Liu Y, Qu Y, Yang Q, Zhang X, Zhu A, Ao H
International immunopharmacology 2025 May 16;155:114513
International immunopharmacology 2025 May 16;155:114513
Polygonatum cyrtonema Hua polysaccharide alleviates ulcerative colitis via gut microbiota-independent modulation of inflammatory immune response.
Shi JY, Wang YJ, Bao QW, Qin YM, Li PP, Wu QQ, Xia CK, Wu DL, Xie SZ
Carbohydrate polymers 2025 May 15;356:123387
Carbohydrate polymers 2025 May 15;356:123387
Engineered probiotics remodel the intestinal epithelial barrier and enhance bacteriotherapy for inflammatory bowel diseases.
Chen Y, Bi S, Zhang X, Chen J, Xin J, Liu Z, Guan Q, Qiu P, Wang P, Liu J
Acta biomaterialia 2025 May 15;198:467-481
Acta biomaterialia 2025 May 15;198:467-481
Edaravone dexborneol provides neuroprotective benefits by suppressing ferroptosis in experimental intracerebral hemorrhage.
Li H, Li X, Li M, Li W, Wei J, Huang Y, Yan H, Lin J, Zhang P
Scientific reports 2025 May 13;15(1):16595
Scientific reports 2025 May 13;15(1):16595
Bufei Yishen formula alleviates airway epithelial cell senescence in COPD by activating AMPK-Sirt1-FoxO3a pathway and promoting autophagy.
Cheng M, Yang M, Tian Y, Liu X, Li J, Zhao P
Scientific reports 2025 May 13;15(1):16584
Scientific reports 2025 May 13;15(1):16584
Transcriptomic analysis and experiment to verify the mechanism of Xiaoyao san in the treatment of irritable bowel syndrome with depression.
Yu J, Li X, Sun Y, Wang L, Zhang Y
Journal of ethnopharmacology 2025 May 12;347:119732
Journal of ethnopharmacology 2025 May 12;347:119732
Exploring the mechanism of Sinisan in the treatment of ulcerative colitis with depression based on UPLC-Q-Orbitrap-MS combined with network pharmacology, molecular docking, and experimental validation.
Zheng M, Liu H, Zhang R, Guo X, Shao Q, Zhang J, Li L, Wang J, Miao S, Shi X, Ma S
Journal of ethnopharmacology 2025 May 12;347:119696
Journal of ethnopharmacology 2025 May 12;347:119696
Enteroendocrine cells regulate intestinal barrier permeability.
Nwako JG, Patel SD, Roach TJ, Gupte SR, Williams SG, Riedman AM, McCauley HA
American journal of physiology. Cell physiology 2025 May 1;328(5):C1501-C1508
American journal of physiology. Cell physiology 2025 May 1;328(5):C1501-C1508
Depletion of Acetyl-CoA Carboxylase 1 Facilitates Epithelial-Mesenchymal Transition in Prostate Cancer Cells by Activating the MAPK/ERK Pathway.
Lai J, Liu S, Chen Y, Chen J, Li J, Liang Z, Mei X, Feng Y, Han Z, Jiang F, Yang S, Wu Y, Tan H, Liu J, He H, Zhong W
MedComm 2025 Mar;6(3):e70126
MedComm 2025 Mar;6(3):e70126
A derivative of tanshinone IIA and salviadione, 15a, inhibits inflammation and alleviates DSS-induced colitis in mice by direct binding and inhibition of RIPK2.
Hu CH, Chen Y, Jin TY, Wang Z, Jin B, Liao J, Ding CY, Zhang A, Tang WY, Zhang LX, Xu LY, Ning FM, Liang G, Wei XH, Wang Y
Acta pharmacologica Sinica 2025 Mar;46(3):672-686
Acta pharmacologica Sinica 2025 Mar;46(3):672-686
Inhibition of histamine receptor 3 alleviates sevoflurane-induced hypomyelination and neurobehavioral deficits.
Che J, Wu Y, Dong J, Jiang X, Yang L, Chen Y, Zhang J
Experimental neurology 2025 Mar;385:115086
Experimental neurology 2025 Mar;385:115086
TSG-6 Protects Against Cerebral Ischemia-Reperfusion Injury via Upregulating Hsp70-1B in Astrocytes.
Qu Y, Yi L, Tang Y, Yang F, Pan BF, Shi S, Qu C, Li F, Wen S, Pan Y
CNS neuroscience & therapeutics 2025 Mar;31(3):e70354
CNS neuroscience & therapeutics 2025 Mar;31(3):e70354
A high cholesterol diet aggravates experimental colitis through SREBP2-modulated endocytosis and degradation of occludin and Zo-1 proteins.
Yang Q, Li Y, Wang X, Ding Q, Tao Y, Li P, Lian X, Chen Y, Zhao L
The FEBS journal 2025 Mar;292(5):1052-1069
The FEBS journal 2025 Mar;292(5):1052-1069
The impact of combined thymol and rosmarinic acid on the intestinal microbiota and barrier function of the piglets challenged by Escherichia coli K88.
Li R, Ding X, Lei M, Li P, Giannenas I, Wang J, Zhu W
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Mar;20:131-144
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2025 Mar;20:131-144
Butylphthalide may inhibit blood-brain barrier disruption through complement-related pathways to alleviate cognitive impairment in epileptic mice.
Zhao L, Chen S, Jin X, Zhuang W, Liu Q, Xiao Y, Xu H
Epilepsy & behavior : E&B 2025 Mar;164:110251
Epilepsy & behavior : E&B 2025 Mar;164:110251
Colon-Targeted Ginseng Polysaccharides-Based Microspheres for Improving Ulcerative Colitis via Anti-Inflammation and Gut Microbiota Modulation.
Huo DY, Li YF, Song LJ, Zhang WX, Li XD, Zhang J, Ren S, Wang Z, Li W
Advanced healthcare materials 2025 Mar;14(6):e2404122
Advanced healthcare materials 2025 Mar;14(6):e2404122
Elevated SPARC Disrupts the Intestinal Barrier Integrity in Crohn's Disease by Interacting with OTUD4 and Activating the MYD88/NF-κB Pathway.
Wang J, He Y, Zhu X, Zhu J, Deng Z, Zhang H, Chen Y, Zhang G, Shi T, Chen W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2409419
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2409419
Intestine-Decipher Engineered Capsules Protect Against Sepsis-induced Intestinal Injury via Broad-spectrum Anti-inflammation and Parthanatos Inhibition.
Yan Y, Li B, Gao Q, Wu M, Ma H, Bai J, Ma C, Xie X, Gong Y, Xu L, Li X, Wang W, Wu Y, Wang J, Wang H, Feng Y, Zhang Y, Li P, Shi H, Ma F, Jia Y, Duan H, Fu X, Wang W, Zhan L, Du X, Zhou H, Liao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2412799
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2412799
The Gut Microbiota-Xanthurenic Acid-Aromatic Hydrocarbon Receptor Axis Mediates the Anticolitic Effects of Trilobatin.
Wu X, Wei J, Ran W, Liu D, Yi Y, Gong M, Liu X, Gong Q, Li H, Gao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2412234
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2412234
The shared mechanism of barrier dysfunction in ulcerative colitis and Alzheimer's disease: DDIT4/IL1β neutrophil extracellular traps drive macrophages-mediated phagocytosis.
Li SH, Huang QH, Yang QQ, Huang Q, Wang DX, Yang J, Huang SH, Zhang SY, Wang JM, Xie LS, Yu SG, Wu QF
International immunopharmacology 2025 Mar 6;149:114188
International immunopharmacology 2025 Mar 6;149:114188
TEPP-46 inhibits glycolysis to promote M2 polarization of microglia after ischemic stroke.
Xia X, Chen W, Zhou T, Zhou F, Lu C, Yan Z, Zhao Q, Su Q
International immunopharmacology 2025 Mar 6;149:114148
International immunopharmacology 2025 Mar 6;149:114148
SVHRSP protects against rotenone-induced neurodegeneration in mice by inhibiting TLR4/NF-κB-mediated neuroinflammation via gut microbiota.
Chen M, Zhang Y, Hou L, Zhao Z, Tang P, Sun Q, Zhao J, Wang Q
NPJ Parkinson's disease 2025 Mar 6;11(1):43
NPJ Parkinson's disease 2025 Mar 6;11(1):43
Indole-3-Propionic Acid Attenuates Neuroinflammation and Cognitive Deficits by Inhibiting the RAGE-JAK2-STAT3 Signaling Pathway.
Hao Z, Ji R, Su Y, Wang H, Yang W, Zhang S, Liu Y, Ma S, Guan F, Cui Y
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Journal of agricultural and food chemistry 2025 Mar 5;73(9):5208-5222
Neutrophil-derived heparin-binding protein increases endothelial permeability in acute lung injury by promoting TRIM21 and the ubiquitination of P65.
Zhang J, Cao Y, Shu W, Dong S, Sun Y, Ma X
Cell biology and toxicology 2025 Mar 5;41(1):55
Cell biology and toxicology 2025 Mar 5;41(1):55
Edaravone dextranol alleviates ferroptosis, Cuproptosis, and blood-brain barrier damage after acute cerebral infarction.
Jin G, Han W, Duan T, Xue Z, Song C, Xu Y, Yu M
Metabolic brain disease 2025 Mar 3;40(3):134
Metabolic brain disease 2025 Mar 3;40(3):134
Houshiheisan modulates the NF-κB/MLCK signaling pathway to protect the endothelial barrier in cerebral small vessel disease.
Cheng HF, Yang QY, Xie YH, Zhang YW, Zhang QX
Journal of ethnopharmacology 2025 Mar 26;344:119502
Journal of ethnopharmacology 2025 Mar 26;344:119502
Sensor-integrated gut-on-a-chip for monitoring senescence-mediated changes in the intestinal barrier.
Brandauer K, Lorenz A, Schobesberger S, Schuller P, Frauenlob M, Spitz S, Ertl P
Lab on a chip 2025 Mar 25;25(7):1694-1706
Lab on a chip 2025 Mar 25;25(7):1694-1706
The dopamine receptor agonist rotigotine attenuated indomethacin-induced enteropathy in the small intestinal mucosa of mice.
Su T, Zhou L, Peng B, Du W, Liu X, Li Z, Zhao Y, Han X, Liu C, Wang Z
Molecular biology reports 2025 Mar 24;52(1):335
Molecular biology reports 2025 Mar 24;52(1):335
Dietary emulsifier carboxymethylcellulose-induced gut dysbiosis and SCFA reduction aggravate acute pancreatitis through classical monocyte activation.
Feng Y, Chen W, Chen J, Sun F, Kong F, Li L, Zhao Y, Wu S, Li Z, Du Y, Kong X
Microbiome 2025 Mar 24;13(1):83
Microbiome 2025 Mar 24;13(1):83
Fisetin alleviates Salmonella typhimurium-induced colitis through the TLR2/TLR4-NF-κB pathway, regulating microbiota, and repressing intracellular bacterial proliferation by focal adhesion kinase.
Li J, Yang Y, Zhang X, Yang Y, Wu Z
European journal of nutrition 2025 Mar 19;64(3):128
European journal of nutrition 2025 Mar 19;64(3):128
Intranasal Delivery of Hydrophobic AC5216 Loaded Nanoemulsion into Brain To Alleviate Chronic Unpredictable Stress-Induced Depressive-like Behaviors.
Zhang Y, Wang Y, Wang H, Bian L, Gao F, Yao H, Xie J
ACS applied materials & interfaces 2025 Mar 19;17(11):16533-16547
ACS applied materials & interfaces 2025 Mar 19;17(11):16533-16547
Shengui Sansheng San alleviates the worsening of blood-brain barrier integrity resulted from delayed tPA administration through VIP/VIPR1 pathway.
Hu J, Li Y, Quan X, Han Y, Chen J, Yuan M, Chen Y, Zhou M, Yu E, Zhou J, Wang D, Wang R, Zhao Y
Chinese medicine 2025 Mar 18;20(1):38
Chinese medicine 2025 Mar 18;20(1):38
Probiotic Delivery for Editing of the Gut Microbiota to Mitigate Colitis and Maintain Hepatic Homeostasis Via Gut-Liver Axis.
Deng J, Hu Y, Zhu P, Yu Y, Chen Q, Wu H, Zha Z, Wang H, Ma Y
ACS nano 2025 Mar 18;19(10):10500-10514
ACS nano 2025 Mar 18;19(10):10500-10514
Vitamin A-Integrated Cinnamaldehyde Nanoemulsion: A Nanotherapeutic Approach To Counteract Liver Fibrosis via Gut-Liver Axis Modulation.
Niu X, Chang G, Xu N, Li R, Niu B, Mao R, Wang S, Li G, Jiang J, Wang L
ACS nano 2025 Mar 18;19(10):10433-10451
ACS nano 2025 Mar 18;19(10):10433-10451
Heat-killed Lacticaseibacillus paracasei 6235 is more effective than live on DSS-induced colitis via modulation of intestinal microbiota and MAPK/NF-κB signaling pathways.
Wang Y, Xie Z, Du L, Wang Q, Zhang L, Wu Y, Han J
Food & function 2025 Mar 17;16(6):2247-2261
Food & function 2025 Mar 17;16(6):2247-2261
Target inhibition of SPAK in choroid plexus attenuates T cell infiltration and demyelination in experimental autoimmune encephalomyelitis.
Qi C, Wang Y, Li X, Zheng C, Gu Y, Hu J, Qiu Y, Xie G, Xu S, Zheng Y, Lv Z, Zheng W
Journal of neuroinflammation 2025 Mar 13;22(1):80
Journal of neuroinflammation 2025 Mar 13;22(1):80
Supplementary Hesperidin Alleviated CPT-11-Induced Diarrhea by Modulating Gut Microbiota and Inhibiting the IL-17 Signaling Pathway.
Zhang X, Yang Y, Wen M, Zhong F, Shu X, Xu R, Xiong P, Zhou Z, He X, Tang X, Wang B, Zhou L, Shen T
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5915-5930
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5915-5930
Oleanolic Acid Alleviates Hyperuricemia via Gut Microbiota Control the Integrity of Gut Barrier and the Expressions of Urate Transporter in Mice.
Zhang T, Liu S, Liu S, Zhao P, Zhang C, Wang X, Meng Y, Lu Y
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5899-5914
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5899-5914
Hawthorn Pectin Alleviates DSS-Induced Colitis in Mice by Ameliorating Intestinal Barrier Function and Modulating Gut Microbiota.
Li T, Chen J, Xu Y, Ji W, Yang S, Wang X
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5872-5885
Journal of agricultural and food chemistry 2025 Mar 12;73(10):5872-5885
Evaluation of Perfusion Cell Culture Conditions in a Double-Layered Microphysiological System Using AI-Assisted Morphological Analysis.
Kutsuzawa N, Goto T, Nakamura H, Maeda M, Kinehara M, Sakagami J, Kimura H
Micromachines 2025 Mar 12;16(3)
Micromachines 2025 Mar 12;16(3)
Enteroendocrine Cells Regulate Intestinal Barrier Permeability.
Nwako JG, Patel SD, Roach TJ, Gupte SR, Williams SG, Riedman AM, McCauley HA
bioRxiv : the preprint server for biology 2025 Mar 12;
bioRxiv : the preprint server for biology 2025 Mar 12;
Why do microplastics aggravate cholestatic liver disease? The NLRP3-mediated intestinal barrier integrity damage matter.
Li S, Yuan Y, Zeng Y, Fang P, Wang J, Liu Y, Xiao F
Environmental pollution (Barking, Essex : 1987) 2025 Mar 1;368:125753
Environmental pollution (Barking, Essex : 1987) 2025 Mar 1;368:125753
Orally-administrable supramolecular probiotic capsules enable cooperative colon-targeted inflammation inhibition for ameliorating ulcerative colitis.
Wang T, Chen J, Shu C, Shen X, Fu Y, Li M, Luo Z
Acta biomaterialia 2025 Mar 1;194:396-410
Acta biomaterialia 2025 Mar 1;194:396-410
Bidirectional transport studies of flavonoids from Alpiniae oxyphyllae fructus by in vitro inflammatory blood-brain barrier model combined with UHPLC-MS/MS analysis.
Wang Y, Chen X, Zhou F, Pan M, Huang Y, Tsunoda M, Zhang Y, Yang H, Li LS, Song Y
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Mar 1;1253:124471
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Mar 1;1253:124471
Respiratory Syncytial Virus Infection Disrupts Airway Epithelial Barriers via IL-33/ST2/MyD88 Signaling Axis.
Miao Q, Yu R, Shi F, Li K, Du X, Gao Y, Li Y, Cui Y, Chen Y, Liu J, Lv Z, Yuan J, Corrigan CJ, Ying S, Wang W
Journal of medical virology 2025 Jun;97(6):e70432
Journal of medical virology 2025 Jun;97(6):e70432
Low-intensity pulsed ultrasound irradiation ameliorates gut inflammation and neuroinflammation in mice with DSS-induced colitis.
Tian S, Hu Y, Zhou Y, Li J, Liu J, Zhou Q
APL bioengineering 2025 Jun;9(2):026117
APL bioengineering 2025 Jun;9(2):026117
H3K18 lactylation-mediated SIX1 upregulation contributes to silica-induced epithelial-mesenchymal transition in airway epithelial cells.
Liu S, He Y, Jin L, Shi S, Zhang J, Xie W, Yang M, Zhang Q, Kong H
Toxicology 2025 Jun;514:154109
Toxicology 2025 Jun;514:154109
Effect of low humidity on the barrier functions of keratinocytes in a reconstructed human epidermal model.
Izutsu-Matsumoto Y, Okano Y, Masaki H, Tokudome Y, Iwabuchi T
International journal of cosmetic science 2025 Jun;47(3):523-534
International journal of cosmetic science 2025 Jun;47(3):523-534
Dual-modality ultrasound/photoacoustic tomography for mapping tissue oxygen saturation distribution in intestinal strangulation.
Zhou J, Ou M, Yuan B, Yan B, Wang X, Qiao S, Huang Y, Feng L, Huang L, Luo Y
Photoacoustics 2025 Jun;43:100721
Photoacoustics 2025 Jun;43:100721
β-Sitosterol Ameliorates Ulcerative Colitis Through Modulation of the AMPK/MLCK Anti-Inflammatory Pathway.
Zhang Y, Jin X, Xia H, Wu X, Chen W, Zhuang M, Tang S
Journal of biochemical and molecular toxicology 2025 Jun;39(6):e70287
Journal of biochemical and molecular toxicology 2025 Jun;39(6):e70287
Bioinspired hydrogel for sustained minocycline release: A superior periodontitis solution.
Liu S, Zheng W, Wang L, Zhang Y, Feng K, Zhang Y, Yang H, Xiao Y, Sun C, Liu X, Lu B, Yin X
Materials today. Bio 2025 Jun;32:101638
Materials today. Bio 2025 Jun;32:101638
Sanghuangporus vaninii polysaccharides alleviates the effects of chlorpyrifos exposure on mouse liver: role of the gut- liver axis.
Liu J, Sun L, Tang Y, Li J, Chen W, Geng J, Zong Y, He Z, Du R
International journal of biological macromolecules 2025 Jun;315(Pt 1):144504
International journal of biological macromolecules 2025 Jun;315(Pt 1):144504
Rehmannia glutinosa polysaccharides alleviate cyclophosphamide-induced immunosuppression by enhancing immunity and restoring intestinal homeostasis.
Yu L, Shi X, Lu X, Zhao X, Yu Y, Fang Y, Wang D
International journal of biological macromolecules 2025 Jun;311(Pt 1):143692
International journal of biological macromolecules 2025 Jun;311(Pt 1):143692
Interaction of osteopontin with α-lactalbumin and their synergistic effects in protecting intestinal barrier injury.
He W, Wang X, Zhang J, Cao H, Ren S, Sun X, Yu H, Zhang G, Li C, Liu L, Wang C, He J
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Food research international (Ottawa, Ont.) 2025 Jun;211:116513
Aging-associated intestinal dysfunction impairs 5-heptadecylresorcinol absorption: Mechanistic insights into transporter-mediated uptake, barrier integrity and inflammatory regulation.
Zhang K, Zhang H, Sun Y, Zhou P, Xue L, Wang Y, Fan M, Qian H, Li Y, Wang L
Food research international (Ottawa, Ont.) 2025 Jun;211:116499
Food research international (Ottawa, Ont.) 2025 Jun;211:116499
Visualizing androgen signaling and assessing its interaction with canonical Wnt signaling pathways in prostate development, morphogenesis, and regeneration.
Adzavon YM, Lee DH, Hiroto A, Park TJ, Chu G, Kim Y, Nikias K, Kim CW, Leung DHL, Liu C, Zeng H, Sun Z
PLoS genetics 2025 Jun;21(6):e1011756
PLoS genetics 2025 Jun;21(6):e1011756
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance.
Zhang S, Wen H, Chen Y, Ning J, Hu D, Dong Y, Yao C, Yuan B, Yang S
Molecular oncology 2025 Jun;19(6):1707-1724
Molecular oncology 2025 Jun;19(6):1707-1724
Acupuncture regulates astrocyte neurotoxic polarization to protect blood-brain barrier integrity in delayed thrombolysis through mediating ERK1/2/Cx43 axis.
Zhang ZH, Gu Y, Huang Z, Liu XY, Xu WT, Zhang XC, Ni GX
IBRO neuroscience reports 2025 Jun;18:604-618
IBRO neuroscience reports 2025 Jun;18:604-618
An anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut-lung axis and NLRP3 inflammasome activation.
Li X, Ding W, Lu Y, Zhu H, Bao W, Liu Y, Lyu J, Zhou L, Li H, Li J, Chen D
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3073-3091
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3073-3091
Protective effects of albiflorin on acetaminophen-induced hepatotoxicity: Regulation of blood-biliary barrier integrity by ATF3.
Lin M, Wang Y, Zhao Y, Zhai X, Hu Y, Luan Q, Lv L, Wang Z, Yao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156722
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156722
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Deng B, Wang K, He H, Xu M, Li J, He P, Liu Y, Ma J, Zhang J, Dong W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Oleic acid regulates CD4+ T cells differentiation by targeting ODC1-mediated STAT5A phosphorylation in Vogt-Koyanagi-Harada disease.
Liao W, Hu R, Ji Y, Zhong Z, Huang X, Cai T, Zhou C, Wang Y, Ye Z, Yang P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156660
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156660
Huang-Lian-Jie-Du decoction inhibits CD4+ T cell infiltration into CNS in MCAO rats by regulating BBB.
Chen C, Li C, Lan X, Ren Z, Zheng Y, Chen D, Xu W, Cui Y, Wang X, Cheng F, Wang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156607
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156607
Dimethyl Itaconate Alleviates Escherichia coli-Induced Endometritis Through the Guanosine-CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae.
He Y, Cai J, Xie X, Zhang X, Qu L, Liu J, Cao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414792
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414792
CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1-Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis.
Han J, Hong R, Cao C, Feng W, Zhuang W, Wang G, Tang J, Yang Y, Zhang C, Zhou A, Qu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414550
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2414550
Long non-coding RNA ANRIL/p65 negative feedback loop protects intestinal barrier function in inflammatory bowel disease.
Yu K, Peng H, Zhang Z, Ye L, Zhan K, Li C, Gan L, Lin Y, Wang Y, Song Y, Mei Z, Liao S, Guo J, Lv L
Non-coding RNA research 2025 Jun;12:167-179
Non-coding RNA research 2025 Jun;12:167-179
Glutamine Attenuates Inflammation and Oxidative Stress in Ulcerative Colitis by Suppressing Wilms' Tumor 1 Associated Protein-Mediated N6-Methyladenosine Modification of Nuclear Receptor Coactivator 3.
Jiang L, Liu S, Ye F, Yu X
Chemical biology & drug design 2025 Jun;105(6):e70110
Chemical biology & drug design 2025 Jun;105(6):e70110
Investigation of postmortem change in the human corneal epithelium via impression cytology.
Deng T, Shintani-Ishida K, Tanioka H, Sotozono C, Ikegaya H
Scientific reports 2025 Jun 6;15(1):20027
Scientific reports 2025 Jun 6;15(1):20027
Probiotic Combination of Limosilactobacillus fermentum HF07 and Lactococcus lactis HF08 Targeting Gut Microbiota-Secondary Bile Acid Metabolism Ameliorates Inflammation and Intestinal Barrier Dysfunction in Aging Colitis.
Liu X, Guan K, Ma Y, Jiang L, Li Q, Liu Y, Mao K, Wang R
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13439-13454
Journal of agricultural and food chemistry 2025 Jun 4;73(22):13439-13454
Enhancing intestinal epithelial microtubule stability could alleviate IBD symptoms.
Yang F, He Z, Pan X, Xie S, Liang X, Geng L, Xu W, Gong S
Cell communication and signaling : CCS 2025 Jun 4;23(1):263
Cell communication and signaling : CCS 2025 Jun 4;23(1):263
Sesamin improved growth and overall health in young animals by enhancing gut-liver axis function.
Chen C, Qi M, Xu Z, Wen J, Tang W, Diao H, Li Z, Chu Y, Feng F, Tang Z
Food & function 2025 Jun 3;16(11):4415-4436
Food & function 2025 Jun 3;16(11):4415-4436
Piezo1 disrupts blood-brain barrier via CaMKII/Nrf2 in ischemic stroke.
Fu H, Yu Y, Wang S, Xu P, Sun Y, Li J, Ge X, Pan S
Cellular and molecular life sciences : CMLS 2025 Jun 28;82(1):259
Cellular and molecular life sciences : CMLS 2025 Jun 28;82(1):259
Disulfiram alleviates epithelial barrier disruption in ozone-induced chronic obstructive pulmonary disease mouse models via inhibiting Gasdermin D-mediated pyroptosis.
Gao J, Han L, Zhang Y, Zhang X, Fei X, Zhang M
International immunopharmacology 2025 Jun 26;159:114887
International immunopharmacology 2025 Jun 26;159:114887
Circ-0000197 derived from porcine milk small extracellular vesicles promotes intestinal barrier function by sponging miR-429.
Wang Y, Chen B, Xuan T, Ouyang K, Chen J, Wang H, Luo J, Sun J, Xi Q, Zhang Y, Chen T
Journal of animal science and biotechnology 2025 Jun 25;16(1):89
Journal of animal science and biotechnology 2025 Jun 25;16(1):89
Photobiomodulation mitigates blood-brain barrier disruption in APP/PS1 mouse model of Alzheimer's disease by activating the AMPK pathway.
Ma C, Ye Y, Shi X, Li N, Mu Z, Tan T, Yin H, Dai J, Liu Y, Chen H
Alzheimer's research & therapy 2025 Jun 23;17(1):141
Alzheimer's research & therapy 2025 Jun 23;17(1):141
Endothelial cell Nrf2 controls neuroinflammation following a systemic insult.
Zou H, Leah T, Huang Z, He X, Mameli E, Caporali A, Dando O, Qiu J
iScience 2025 Jun 20;28(6):112630
iScience 2025 Jun 20;28(6):112630
Excretory/secretory products from Hymenolepis nana adult worms alleviate ulcerative colitis in mice via tuft/IL-13 signaling pathway.
Mou R, Cui X, Wang H, Zhang Z, Cheng Y, Wu W, Li J, Zhang K
Parasites & vectors 2025 Jun 20;18(1):230
Parasites & vectors 2025 Jun 20;18(1):230
Betulinic Acid Reduces Intestinal Inflammation and Enhances Intestinal Tight Junctions by Modulating the PPAR-γ/NF-κB Signaling Pathway in Intestinal Cells and Organoids.
Zheng X, Cao Z, Wang M, Yuan R, Han Y, Li A, Wang X
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
Pretreatment with Citrus reticulata 'Chachi' Polysaccharide Alleviates Alcohol-Induced Gastric Ulcer by Inhibiting NLRP3/ASC/Caspase-1 and Nrf2/HO-1 Signaling Pathways.
Liang H, Liang Y, Wu L, Lin L, Yao Y, Deng J, Xu J, Li H, Gao F, Xing W, Yu M, Jia X, Wei M, Li C, Zheng G
Nutrients 2025 Jun 20;17(13)
Nutrients 2025 Jun 20;17(13)
Idebenone Orchestrates Anti-Inflammatory and Antioxidant Responses to Alleviate Brain Injury After Intracerebral Hemorrhage in Mice.
Chen C, Cao L, Xue M, Zhu N
Journal of integrative neuroscience 2025 Jun 19;24(6):37182
Journal of integrative neuroscience 2025 Jun 19;24(6):37182
Liver-Skin Microphysiological System for Evaluating Topical Drug Delivery-Induced Liver Injury.
Du K, Wang B, Yang N, Jin J, Liu W, Pu F, Zou L, Qu Z, Chen L
ACS omega 2025 Jun 17;10(23):24284-24295
ACS omega 2025 Jun 17;10(23):24284-24295
Polystyrene nanoplastics aggravate house dust mite induced allergic airway inflammation through EGFR/ERK-dependent lung epithelial barrier dysfunction.
Wang Q, He W, Zhou Y, Feng R, Wang Y, Liu L, Yuan Y, Dai J, Liu Y, Zhang X
Ecotoxicology and environmental safety 2025 Jun 15;298:118329
Ecotoxicology and environmental safety 2025 Jun 15;298:118329
Transcranial magnetic stimulation through attenuating blood-spinal cord barrier disruption and reducing inflammatory response to improve motor function in rats with spinal cord injury.
Xu Q, Zhang Z, Zhai Y, Chen J, Xu J, Chen H, Lu J
Brain research bulletin 2025 Jun 15;226:111385
Brain research bulletin 2025 Jun 15;226:111385
Tumor-derived exosomal miR-425-5p and miR-135b-3p enhance colorectal cancer progression through immune suppression and vascular permeability promotion.
Feng CZ, Zhong SQ, Ye SW, Zheng Z, Sun H, Zhou SH
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
World journal of gastrointestinal oncology 2025 Jun 15;17(6):106161
Integrating transcriptomics, metabolomics, and microbiomics to explore the mechanism of action of bran-fried Atractylodes lancea rhizome polysaccharide in ameliorating the enhanced pharmacological effects of dextran sodium sulfate-induced colitis.
Yao D, Ma C, Ke C, Wang D, Xu K, Liu Y, Qu L
Journal of ethnopharmacology 2025 Jun 12;349:119805
Journal of ethnopharmacology 2025 Jun 12;349:119805
The Effects of Pretreated and Fermented Corn Stalks on Growth Performance, Nutrient Digestion, Intestinal Structure and Function, and Immune Function in New Zealand Rabbits.
Jia X, Dun Y, Xiang G, Wang S, Zhang H, Zhou W, Li Y, Liang Y
Animals : an open access journal from MDPI 2025 Jun 12;15(12)
Animals : an open access journal from MDPI 2025 Jun 12;15(12)
Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.
Dong C, Zhou Y, Shen X, Hu S, Duan K, Chen T, Li W, Sun X, Li P, Wang P, Han Y, Li D, Zhi Q, Zhou J
Cell death & disease 2025 Jun 11;16(1):444
Cell death & disease 2025 Jun 11;16(1):444
Comparison of Efavirenz and Dolutegravir on Gut Microbiome and Gut Barrier Functions.
Huang YX, Tang Q, Fu SH, Zhong HJ, Liu Z, Zhong QY, Wang YH, Luo YD, Li XY, Chen S, Zhu HP
ACS omega 2025 Jun 10;10(22):23099-23110
ACS omega 2025 Jun 10;10(22):23099-23110
PCP protein Prickle 1 regulates Sertoli cell and testis function via cytoskeletal organization through the recruitment of multiple regulatory proteins.
Wang L, Bu T, Gao S, Yun D, Chen H, Cheng CY, Sun F
American journal of physiology. Cell physiology 2025 Jun 1;328(6):C2032-C2056
American journal of physiology. Cell physiology 2025 Jun 1;328(6):C2032-C2056
KLF10 Induced by Hypothermic Machine Perfusion Alleviates Renal Inflammation Through BIRC2 /Noncanonical NF-κB Pathway.
Hu Q, Chen H, Lan J, Chen Y, Liu Z, Xiong Y, Zhou W, Zhong Z, Ye Q
Transplantation 2025 Jun 1;109(6):e273-e286
Transplantation 2025 Jun 1;109(6):e273-e286
Probiotic domestication and engineering enable one-shot treatment for bladder mucosal repair.
Li M, Jin S, Lu Y, Sun Q, Zhang Y, Jiang P, Zhu S, Luo Y, Zhao SC, Li C, Feng N
Biomaterials 2025 Jul;318:123123
Biomaterials 2025 Jul;318:123123
Xuefu Zhuyu Decoction Improves Blood-Brain Barrier Integrity in Acute Traumatic Brain Injury Rats via Regulating Adenosine.
Wang Y, Yan QJ, Hu E, Wu Y, Ding RQ, Chen Q, Cheng MH, Yang XY, Tang T, Li T
Chinese journal of integrative medicine 2025 Jul;31(7):624-634
Chinese journal of integrative medicine 2025 Jul;31(7):624-634
Ethanolic Extract of Atractylodis Rhizoma Ameliorates DSS-Induced Ulcerative Colitis via Improving Intestinal Barrier Function Through the Rho-Associated Kinase/Myosin Light Chain Pathway.
Gao Z, Huang P, Yu X, Dong R, Lin Y, Tu J, Chen L, Cao Y, Liu Y, Yang D, Cao G
Journal of medicinal food 2025 Jul;28(7):694-707
Journal of medicinal food 2025 Jul;28(7):694-707
RETRACTED ARTICLE: Copper Exposure Destroys the Integrity of the Blood-Testis Barrier (BTB) Through p38 MAPK-Meditated Autophagy Pathways.
Deng H, Lou Y, He R, Deng J, Zhu Y, Wu X, Guo H
Biological trace element research 2025 Jul;203(7):3987
Biological trace element research 2025 Jul;203(7):3987
Andrographolide and its sulfated metabolite alleviated DSS-induced inflammatory bowel disease through regulating inflammation and immune via MAPK/NLRP3 pathways and the balance of Th17/Treg cells.
Zhang HL, Chang J, Sun CP, Huo ZP, Feng YL, Li PY, Jia YX, Hui SW, Zhu QM, Cai JY, He Y, Qiu F, Zhang J
Molecular immunology 2025 Jul;183:313-320
Molecular immunology 2025 Jul;183:313-320
Acupuncture Alleviates Blood-Brain Barrier Damage After Delayed rtPA Thrombolysis for Acute Ischemic Stroke by Regulating Ferroptosis.
Huang Z, Lu T, Liu X, Zhang Z, Song Y, Li Y, Xu W, Zhang X, Ni G
Brain and behavior 2025 Jul;15(7):e70644
Brain and behavior 2025 Jul;15(7):e70644
Echinacoside alleviates type 2 diabetes mellitus through inhibiting hepatic gluconeogenesis via gut bacterial-fungal trans-kingdom network reconstruction.
Fan L, Liu J, Li L, Yang X, Zhao Q, Zhao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156802
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156802
Crataegus pinnatifida polysaccharide alleviates DSS-induced colitis in mice by regulating the intestinal microbiota and enhancing arginine biosynthesis.
Wei FH, Xie WY, Zhao PS, Ji ZH, Gao F, Chen CZ, Zhang Z, Gao W, Yuan B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156794
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156794
Music intervention mitigates LPS-induced gut barrier disruption and immune stress in broilers via TLR4/NF-κB regulation.
Jin S, Wang H, Gong H, Guo L, Zhang H, Zhang J, Chang Q, Li J, Zhang R, Bao J
Poultry science 2025 Jul;104(7):105189
Poultry science 2025 Jul;104(7):105189
ORF3a is a key driver of maternal SARS-CoV-2 infection-associated placental dysfunction.
Mysorekar I, Kumar D, McColl E, Karvas R, Jones B, Tran L, Diveley E, Jash S, Sharma S, Kelly J, Theunissen T
Research square 2025 Jul 3;
Research square 2025 Jul 3;
Endoplasmic reticulum-mitochondria coupling prompts ZBP1-mediated RPE cell PANoptosis in age-related macular degeneration.
Zhang A, Wei TT, Yin H, Tan CY, Han C, Yao Y, Zhu L
Communications biology 2025 Jul 29;8(1):1118
Communications biology 2025 Jul 29;8(1):1118
An engineered antimicrobial peptide Z-FV7 demonstrates bactericidal efficacy against multidrug-resistant Escherichia coli in a murine model of endometritis.
Su J, Yang H, Wang S, Wang X, Li W, Meng W, Sun J, Zhu Y
Veterinary research 2025 Jul 25;56(1):159
Veterinary research 2025 Jul 25;56(1):159
Platelet-derived microparticles increase the interaction of colorectal cancer cells with the endothelium to promote metastatic events.
Papiewska-Pająk I, Kassassir H, Moczkowska W, Braun M, Rybicka A, Boncela J, Kowalska MA
Journal of translational medicine 2025 Jul 25;23(1):843
Journal of translational medicine 2025 Jul 25;23(1):843
The promoting effect of high-fat diet-induced trained immunity on ulcerative colitis and the mechanism of the therapeutic effect of Dahuang Mudan Decoction.
Li P, Xu R, Chen H, Cao S, Xie X, Xu B, Chen Y, Xie X, Yang C, Wang Q, Luo X, Zhou L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156893
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156893
Poliumoside alleviates microglia-mediated inflammation and blood-brain barrier disruption via modulating the polarization of microglia after ischemic stroke in mice.
Gao Y, Wang J, Zhang C, Wang H, Wang B, Zhang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156881
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156881
Nuciferine ameliorates blood-brain barrier disruption post-ischemic stroke via inhibiting the JAK2/STAT3 pathway.
Li J, Liu M, Fan M, Tian Q, Wang J, Du Y, Yu J, Li X, Yang L, Zhao M, Gao Y, Sun T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156829
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156829
Qingshu Yiqi decoction ameliorates exertional heat stroke-induced intestinal barrier injury via NF-κB/MLC pathway and gut microbiota.
Ma W, Wang M, Chen J, Wang Y, Chen J, Pei Y, Gong Y, You J, Cao Y, Zhou J, Ma J, Chang W, Zhu H, Song Q, Li L, Xu S, Zhu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156723
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156723
PEAK1 maintains tight junctions in intestinal epithelial cells and resists colitis by inhibiting autophagy-mediated ZO-1 degradation.
Zhang Z, Xie Y, Yi Q, Liu J, Yang L, Wang R, Cai J, Li X, Feng X, Yao S, Pan Z, Paolino M, Zhou Q
Nature communications 2025 Jul 24;16(1):6777
Nature communications 2025 Jul 24;16(1):6777
Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice.
Wu Y, Zhang Y, Yu Y, Wang X, Zhen Z, Yuan Y, Xie B, Han M, Wang M, Zhang X, Sun X, Wen X, Hashimoto K, Shang Y, Yuan S, Zhang J
Nature communications 2025 Jul 23;16(1):6779
Nature communications 2025 Jul 23;16(1):6779
Calcium transients regulate the apical emergence of basally located progenitors during Xenopus skin development.
Christodoulou N, Skourides PA
Nature communications 2025 Jul 19;16(1):6650
Nature communications 2025 Jul 19;16(1):6650
Exploring the Mechanism of Kidney Injury in Mice Induced by High-Fat Diet and Polystyrene Nanoplastics Co-Exposure Through the Kidney-Gut Axis.
Dong J, Yang F, Xu Y, Zhao Q, Li X, Liu T, Tang Y
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17956-17966
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17956-17966
Engineered Exosomes Delivering bta-miR-223 Alleviate Staphylococcus aureus-Induced Mastitis in Mice via the TLR4/NF-κB Signaling Pathway.
Wang Y, Ouyang K, Nie Y, Yang J, Liao Y, Chen X, Wang H, Luo J, Sun J, Xi Q, Shen B, Chen T, Zhang Y
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17824-17832
Journal of agricultural and food chemistry 2025 Jul 16;73(28):17824-17832
Lyophilized apoptotic vesicles restore DNA damage and mitochondria dysfunction to ameliorate radiation enteritis.
Yang B, Luo H, Yan X, Li L, Huang Z, Jiang Y, Mao X, Shi S, Ma L
Journal of nanobiotechnology 2025 Jul 16;23(1):521
Journal of nanobiotechnology 2025 Jul 16;23(1):521
Long term chlorantraniliprole exposure induced intestinal and cognitive impairment via inducing lipid and amino acid metabolism dysfunction.
Wang XY, Li ZP, Feng BY, Cheng J, Zhu JX, Xu GH, Huang WF, Yi LT
Ecotoxicology and environmental safety 2025 Jul 15;300:118470
Ecotoxicology and environmental safety 2025 Jul 15;300:118470
Peptide Cy(RL-QN15) alleviates UVB-induced skin aging by promoting the repair of barrier.
Kang Z, Yin S, Han X, Liu X, Peng Y, Jia Q, Fu Z, Li Y, Wu Y, Xiao Z, Li Z, Wang Y, Luo M, Yang X
Ecotoxicology and environmental safety 2025 Jul 15;300:118465
Ecotoxicology and environmental safety 2025 Jul 15;300:118465
Kushenol I combats ulcerative colitis via intestinal barrier preservation and gut microbiota optimization.
He XD, Li M, Zuo XD, Ni HY, Han YX, Hu YK, Yu J, Yang XX
World journal of gastroenterology 2025 Jul 14;31(26):105656
World journal of gastroenterology 2025 Jul 14;31(26):105656
Targeting modulation of the choroid plexus blood-CSF barrier and CSF hypersecretion via lipid nanoparticle-mediated co-delivery of siRNA and resveratrol.
Wang Q, Xia X, Zhang H, Li Y, Zhu L, Shi Y, Tang Y, Cheng J, Hui X, Gao H
Nature communications 2025 Jul 10;16(1):6389
Nature communications 2025 Jul 10;16(1):6389
Low-dose polystyrene microplastics exposure increases susceptibility to obesity-induced MASLD via disrupting intestinal barrier integrity and gut microbiota homeostasis.
Wei G, Zhang K, Shen FJ, Xie RR, Wang FW, Guo HQ, Liu L
Ecotoxicology and environmental safety 2025 Jul 1;299:118310
Ecotoxicology and environmental safety 2025 Jul 1;299:118310
α7 nicotinic acetylcholine receptors regulate radial glia fate in the developing human cortex.
Mukhtar T, Siebert CV, Wang Y, Pebworth MP, White ML, Wu T, Huang TI, Zuo G, Ross J, Baltazar J, Upadhyay V, Shankar M, Zhou L, Lombardi-Coronel I, Mandala I, Adam MA, Wang S, Bi Q, Hoekman MFM, Li J, Kriegstein AR
Nature communications 2025 Jul 1;16(1):5925
Nature communications 2025 Jul 1;16(1):5925
Cold environment regulates ischemic stroke through modulation of gut microbiota.
Zhou X, Wei C, Liu J, Xia X, Wang L, Li X
Scientific reports 2025 Jul 1;15(1):21558
Scientific reports 2025 Jul 1;15(1):21558
Ferroptosis is involved in the IL-9-induced intestinal barrier injury in sepsis: an experimental animal and translational study.
Sun JK, Huangfu XT, Yin X, Nie S, Deng YH, Ye ZY, Zhou XH, Wang X, Si YN
International journal of surgery (London, England) 2025 Jul 1;111(7):4314-4324
International journal of surgery (London, England) 2025 Jul 1;111(7):4314-4324
Butyrate protects the intestinal barrier by upregulating Fut2 expression via MEK4-JNK signaling pathway activation.
Zhang DD, Huang ZX, Liu XC, Ding XP, Li L, He Y, Ai Q, Li LQ, Bao L
Pediatric research 2025 Jan;97(1):128-137
Pediatric research 2025 Jan;97(1):128-137
Wolfberry Honey and Its Extract Alleviate Dextran Sodium Sulfate-Induced Ulcerative Colitis by Improving Intestinal Barrier Function and Reducing Oxidative Stress and Inflammation.
Yuan J, Wu Q, Guo Y, Tang Y, Gao S, Li T, Xuan H
Molecular nutrition & food research 2025 Jan;69(2):e202400726
Molecular nutrition & food research 2025 Jan;69(2):e202400726
Astrocytes-Secreted WNT5B Disrupts the Blood-Brain Barrier Via ROR1/JNK/c-JUN Cascade During Meningitic Escherichia Coli Infection.
Qu X, Yang R, Tan C, Chen H, Wang X
Molecular neurobiology 2025 Jan;62(1):661-673
Molecular neurobiology 2025 Jan;62(1):661-673
Slit2 Promotes H(2)O(2)-Induced Lens Epithelial Cells Oxidative Damage and Age-Related Cataract.
Fu L, Yang Q, Han Y, Sun F, Jin J, Wang J
Current eye research 2025 Jan;50(1):41-50
Current eye research 2025 Jan;50(1):41-50
Characteristics of polycystic ovary syndrome rat models induced by letrozole, testosterone propionate and high-fat diets.
Hu R, Huang Y, Liu Z, Dong H, Ma W, Song K, Xu X, Wu X, Geng Y, Li F, Zhang M, Song Y
Reproductive biomedicine online 2025 Jan;50(1):104296
Reproductive biomedicine online 2025 Jan;50(1):104296
Biased constitutive signaling of the G protein-coupled receptor GPR35 suppresses gut barrier permeability.
Quon T, Lin LC, Ganguly A, Hudson BD, Tobin AB, Milligan G
The Journal of biological chemistry 2025 Jan;301(1):108035
The Journal of biological chemistry 2025 Jan;301(1):108035
Astragalus polysaccharide alleviates mastitis disrupted by Staphylococcus aureus infection by regulating gut microbiota and SCFAs metabolism.
Li K, Ran X, Han J, Ding H, Wang X, Li Y, Guo W, Li X, Guo W, Fu S, Bi J
International journal of biological macromolecules 2025 Jan;286:138422
International journal of biological macromolecules 2025 Jan;286:138422
Verteporfin combined with ROCK inhibitor promotes the restoration of corneal endothelial cell dysfunction in rats.
Zhang X, Liu H, Wan C, Li Y, Ren C, Lu J, Liu Y, Yang Y
Biochemical pharmacology 2025 Jan;231:116641
Biochemical pharmacology 2025 Jan;231:116641
Discovery of a novel AhR-CYP1A1 axis activator for mitigating inflammatory diseases using an in situ functional imaging assay.
Zhang F, Zhao B, Fan Y, Qin L, Shi J, Chen L, Xu L, Jin X, Sun M, Deng H, Zeng H, Xiao Z, Yang X, Ge G
Acta pharmaceutica Sinica. B 2025 Jan;15(1):508-525
Acta pharmaceutica Sinica. B 2025 Jan;15(1):508-525
Pimpinellin mitigates DSS-induced ulcerative colitis in mice by reducing inflammation and regulating gut microbiota.
Lv B, Hou L, Zhang H, Hao C, Song Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156308
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156308
Toosendanin alleviates acute lung injury by reducing pulmonary vascular barrier dysfunction mediated by endoplasmic reticulum stress through mTOR.
Mao X, Wang C, Tang H, Liu X, Wei C, Yin F, Fu T, Fang Y, Yu K, Zhang Z, Wu C, Liu H, Le A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156277
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156277
Dachengqi decoction ameliorated liver injury in liver fibrosis mice by maintaining gut vascular barrier integrity.
Shuhan W, Jinxiao L, Luorui S, Liuying C, Fangyuan Z, Mengqi Z, Qifeng L, Yuju C, Junli Z, Yao W, Shenglan Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156272
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156272
C9orf72 Alleviates DSS‑Induced Ulcerative Colitis via the cGAS-STING Pathway.
Wang Y, Xu T, Wang W
Immunity, inflammation and disease 2025 Jan;13(1):e70139
Immunity, inflammation and disease 2025 Jan;13(1):e70139
Supervillin-Mediated ZO-1 Downregulation Facilitates Migration of Cisplatin-Resistant HCT116 Colorectal Cancer Cells.
Hong Y, Li X, Mao R, Zhou F, Li S, Zhu C, Jin L
Journal of cellular biochemistry 2025 Jan;126(1):e30699
Journal of cellular biochemistry 2025 Jan;126(1):e30699
Luteolin Alleviates Ulcerative Colitis in Mice by Modulating Gut Microbiota and Plasma Metabolism.
Yang S, Duan H, Yan Z, Xue C, Niu T, Cheng W, Zhang Y, Zhao X, Hu J, Zhang L
Nutrients 2025 Jan 7;17(2)
Nutrients 2025 Jan 7;17(2)
Ubiquitin-specific protease 25 ameliorates ulcerative colitis by regulating the degradation of phosphor-STAT3.
Liu Z, Liu J, Wei Y, Li J, Zhang J, Yu R, Yang Q, Miao Y, Dong W
Cell death & disease 2025 Jan 7;16(1):5
Cell death & disease 2025 Jan 7;16(1):5
GYY4137 ameliorates blood brain barrier damage by inhibiting autophagy mediated occludin degradation in cardiac arrest and resuscitation.
Duan P, Li X, Bi Y, Feng W, Jin Z, Zhang X, He G, An D, Wen Z, Zhang B
Scientific reports 2025 Jan 6;15(1):905
Scientific reports 2025 Jan 6;15(1):905
Intestinal Barrier Damage and Growth Retardation Caused by Exposure to Polystyrene Nanoplastics Through Lactation Milk in Developing Mice.
Zhou C, Wu H, Zhang L, Xiao X, Wang X, Li M, Cai R, You J, Chen Q, Yang Y, Tian X, Bai Q, Chen Y, Bao H, Liu T
Nanomaterials (Basel, Switzerland) 2025 Jan 4;15(1)
Nanomaterials (Basel, Switzerland) 2025 Jan 4;15(1)
Dihydromyricetin attenuates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating oxidative stress and inhibiting NLRP3 inflammasome.
Chen X, He X, Du X, Huang Z, Jia G, Zhao H
Journal of animal science 2025 Jan 4;103
Journal of animal science 2025 Jan 4;103
YiMu-QingGong san alleviates lipopolysaccharide-induced endometritis in mice via inhibiting inflammation and oxidative stress through regulating macrophage polarization.
Yu Y, Mao N, Yu L, Lin F, Shi X, Lu X, Yang Y, Lu Y, Wang D
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118992
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118992
Ursodeoxycholic acid protects against sepsis-induced acute kidney injury by activating Nrf2/HO-1 and inhibiting NF-κB pathway.
Lou Y, Shi H, Sha N, Li F, Gu X, Lin H
BMC nephrology 2025 Jan 30;26(1):45
BMC nephrology 2025 Jan 30;26(1):45
Mechanistic study of the effect of a high-salt diet on the intestinal barrier.
Chen L, Tang J, Xia Y, Wang J, Xia LN
Scientific reports 2025 Jan 30;15(1):3826
Scientific reports 2025 Jan 30;15(1):3826
Cecropin AD ameliorates pneumonia and intestinal injury in mice with mycoplasma pneumoniae by mediating gut microbiota.
Li B, Liu M, Du W, Wang S, Xu Z, Zhang X, Zhang Y, Hua S
BMC veterinary research 2025 Jan 29;21(1):39
BMC veterinary research 2025 Jan 29;21(1):39
Co-exposure to polyethylene microplastics and house dust mites aggravates airway epithelial barrier dysfunction and airway inflammation via CXCL1 signaling pathway in a mouse model.
Hu JQ, Wang CC, Ma RX, Qi SQ, Fu W, Zhong J, Cao C, Zhang XL, Liu GH, Gao YD
International immunopharmacology 2025 Jan 27;146:113921
International immunopharmacology 2025 Jan 27;146:113921
Interleukin 8 exacerbates age-related hearing loss through regulating perivascular-resident macrophage-like melanocytes viability and the permeability of the endothelial cells.
Chen S, Zhou Y, Wu J, Lin J, Hong Z, Wang Y, Han Y, Luo X
International immunopharmacology 2025 Jan 27;146:113820
International immunopharmacology 2025 Jan 27;146:113820
Lentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice.
Zhang X, Wang L, Khan AI, Rehman AU, Khinsar KH, Xin Y
AMB Express 2025 Jan 22;15(1):11
AMB Express 2025 Jan 22;15(1):11
Let-7f-5p/AIMP1/ZO-1 axis mediates blood-brain barrier dysfunction in neuromyelitis optica spectrum disorders.
Yuan C, Guo RY, Yin B, Zhang L, Liu J, Li B
Clinical and experimental immunology 2025 Jan 21;219(1)
Clinical and experimental immunology 2025 Jan 21;219(1)
Trimetazidine: Activating AMPK Signal to Ameliorate Coronary Microcirculation Dysfunction after Myocardial Infarction.
Qu X, Yang P, Jiao L, Yin Y
Frontiers in bioscience (Landmark edition) 2025 Jan 20;30(1):25565
Frontiers in bioscience (Landmark edition) 2025 Jan 20;30(1):25565
Lactobacillus rhamnosus LC-STH-13 ameliorates the progression of SLE in MRL/lpr mice by inhibiting the TLR9/NF-κB signaling pathway.
Liao W, Zhang X, Jia C, Chen W, Cai Y, Zhang H, Wei J, Chen T
Food & function 2025 Jan 20;16(2):475-486
Food & function 2025 Jan 20;16(2):475-486
Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners.
Qin X, Shi H, Li H, Chu B, Zhang J, Wen Z, Sun X, Wang H, He Y
Nature communications 2025 Jan 2;16(1):33
Nature communications 2025 Jan 2;16(1):33
Multi-omics analysis and experimental verification reveal testicular fatty acid metabolism disorder in non-obstructive azoospermia.
Li Z, Xiang YJ, Zou ZC, Feng YM, Wang H, Chen WQ, Ge X, Ma JZ, Jing J, Yao B
Zoological research 2025 Jan 18;46(1):177-192
Zoological research 2025 Jan 18;46(1):177-192
Peptide-drug conjugates repolarize glioblastoma-associated macrophages to resensitize chemo-immunotherapy of glioblastoma.
Li Z, Jiang S, Wang J, Li W, Yang J, Liu W, Gao H, Huang Y, Ruan S
Science advances 2025 Jan 17;11(3):eadr8841
Science advances 2025 Jan 17;11(3):eadr8841
Exploring the Underlying Mechanism of Weiling Decoction Alleviates Cold-Dampness Diarrhea Based on Network Pharmacology, Transcriptomics, Molecular Docking and Experimental Validation.
Zhang Y, Zhang S, Fan Y, Huang S, Wang S, Hao Z, Shen J
Pharmaceuticals (Basel, Switzerland) 2025 Jan 16;18(1)
Pharmaceuticals (Basel, Switzerland) 2025 Jan 16;18(1)
Ganoderic Acid A Alleviates Severe Acute Pancreatitis by Modulating Gut Homeostasis and Inhibiting TLR4-NLRP3 Signaling.
Zhang L, Wang K, Huang L, Deng B, Chen C, Zhao K, Wang W
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1563-1579
Journal of agricultural and food chemistry 2025 Jan 15;73(2):1563-1579
The Role of TRPV1/CGRP Pathway Activated by Prevotella melaninogenica in Pathogenesis of Oral Lichen Planus.
Xu P, Shao R, Zhu P, Fei J, He Y
International journal of molecular sciences 2025 Jan 14;26(2)
International journal of molecular sciences 2025 Jan 14;26(2)
Neohesperidin Mitigates High-Fat-Diet-Induced Colitis In Vivo by Modulating Gut Microbiota and Enhancing SCFAs Synthesis.
Lu K, Shan S, Zeng Y, Yang G
International journal of molecular sciences 2025 Jan 10;26(2)
International journal of molecular sciences 2025 Jan 10;26(2)
The efficacy and active compounds of Chaihuang Qingyi Huoxue granule to Ameliorate intestinal mucosal barrier injury in rats with severe acute pancreatitis by suppressing the HMGB1/TLR4/NF-κB signaling pathway.
Liu JQ, Hao WA, Liu YL, Yang D, Wang HL, Zhao L, Chen H, Li L, Jiang CL, Zhou X, Fu J, Li Z
International immunopharmacology 2025 Jan 10;144:113632
International immunopharmacology 2025 Jan 10;144:113632
Selenoprotein M protects cardiac endothelial cell integrity against high-glucose stress via enhancing Parkin-mediated mitophagy.
Zhao B, Tan WL, Yu BB, Fan J, Liu C, Liu J, Liu Z
Molecular and cellular endocrinology 2025 Jan 1;595:112392
Molecular and cellular endocrinology 2025 Jan 1;595:112392
Bisphenol S exposure promotes stemness of triple-negative breast cancer cells via regulating Gli1-mediated Sonic hedgehog pathway.
Yi K, Chen W, Zhou X, Xie C, Zhong C, Zhu J
Environmental research 2025 Jan 1;264(Pt 1):120293
Environmental research 2025 Jan 1;264(Pt 1):120293
SPHK1/S1PR1/PPAR-α axis restores TJs between uroepithelium providing new ideas for IC/BPS treatment.
Zhang J, Ge Q, Du T, Kuang Y, Fan Z, Jia X, Gu W, Chen Z, Wei Z, Shen B
Life science alliance 2025 Feb;8(2)
Life science alliance 2025 Feb;8(2)
Therapeutic Potential of Vanillic Acid in Ulcerative Colitis Through Microbiota and Macrophage Modulation.
Zhao H, Fu X, Wang Y, Shang Z, Li B, Zhou L, Liu Y, Liu D, Yi B
Molecular nutrition & food research 2025 Feb;69(4):e202400785
Molecular nutrition & food research 2025 Feb;69(4):e202400785
Inhibition of miR-142-3p promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury by targeting FoxM1.
Wang Y, Jia Z, Zheng M, Wang P, Gao J, Zhang X, Zhou T, Zu G
Molecular and cellular biochemistry 2025 Feb;480(2):1121-1135
Molecular and cellular biochemistry 2025 Feb;480(2):1121-1135
N-Acetylcysteine Alleviates Necrotizing Enterocolitis by Depressing SESN2 Expression to Inhibit Ferroptosis in Intestinal Epithelial Cells.
Gao C, Wang L, Fu K, Cheng S, Wang S, Feng Z, Yu S, Yang Z
Inflammation 2025 Feb;48(1):464-482
Inflammation 2025 Feb;48(1):464-482
Activation of PPARγ regulates M1/M2 macrophage polarization and attenuates dextran sulfate sodium salt-induced inflammatory bowel disease via the STAT-1/STAT-6 pathway.
Xue L, Wu YY
The Kaohsiung journal of medical sciences 2025 Feb;41(2):e12927
The Kaohsiung journal of medical sciences 2025 Feb;41(2):e12927
Lysosome-Targeting Protein Degradation Through Endocytosis Pathway Triggered by Polyvalent Nano-Chimera for AD Therapy.
Wang X, Chen S, Xia X, Du Y, Wei Y, Yang W, Zhang Y, Song Y, Lei T, Huang Q, Gao H
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(5):e2411061
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(5):e2411061
Geniposide Protects Against Myocardial Infarction Injury via the Restoration in Gut Microbiota and Gut-Brain Axis.
Chen J, Zhu T, Yang J, Shen M, Wang D, Gu B, Xu J, Zhang M, Hao X, Tang Z, Tong J, Du Y, Zhang B, Li H, Xu M
Journal of cellular and molecular medicine 2025 Feb;29(3):e70406
Journal of cellular and molecular medicine 2025 Feb;29(3):e70406
Single-Cell Transcriptomic Reveals the Involvement of Cell-Cell Junctions in the Early Development of Hypertrophic Cardiomyopathy.
Wang D, Lin M, Wang R, Huang X, Liang Y, Wang X, Chen Y, Gao Y, Guo H, Liang H, Li X
Journal of cellular and molecular medicine 2025 Feb;29(3):e70366
Journal of cellular and molecular medicine 2025 Feb;29(3):e70366
Effects of exopolysaccharides form Lactobacillus plantarum KX041 on high fat diet-induced gut microbiota and inflammatory obesity.
Yue F, Han H, Xu J, Yao X, Qin Y, Zhang L, Sun X, Huang J, Zhang F, Lü X
International journal of biological macromolecules 2025 Feb;289:138803
International journal of biological macromolecules 2025 Feb;289:138803
A comparative study on in vitro models of necrotizing enterocolitis induced by single and combined stimulation.
Gao C, Feng Z, Wang L, Fu K, Yang Z, Wang S, Yu S
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2025 Feb;26(1):62-66
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2025 Feb;26(1):62-66
Muribaculum intestinale-derived 3-hydroxybutyric acid from Heterophyllin B attenuated pulmonary fibrosis through IDO1-mediated ferroptosis.
Chen C, Wang J, Cheng M, Xie H, Li W, Zhang C
Pharmacological research 2025 Feb;212:107587
Pharmacological research 2025 Feb;212:107587
Discovery of anti-inflammatory molecules from Dendrobium officinale based on activity labelled molecular networking and its alleviation effect on ulcerative colitis.
Dai J, Wang W, He F, Yu X, Liu Z, Wang Y, Zou D
Food research international (Ottawa, Ont.) 2025 Feb;203:115888
Food research international (Ottawa, Ont.) 2025 Feb;203:115888
Xylooligosaccharide and Akkermansia muciniphila synergistically ameliorate insulin resistance by reshaping gut microbiota, improving intestinal barrier and regulating NKG2D/NKG2DL signaling in gestational diabetes mellitus mice.
Wang J, Wu Y, Yang J, Ying S, Luo H, Zha L, Li Q
Food research international (Ottawa, Ont.) 2025 Feb;201:115634
Food research international (Ottawa, Ont.) 2025 Feb;201:115634
Long-term effects of Nε-carboxymethyllysine intake on intestinal barrier permeability: Associations with gut microbiota and bile acids.
Qiang X, Wang X, Liang S, Li S, Lv Y, Zhan J
Food research international (Ottawa, Ont.) 2025 Feb;201:115543
Food research international (Ottawa, Ont.) 2025 Feb;201:115543
Lactobacillus acidophilus JYLA-126 Ameliorates Obesity-Associated Metabolic Disorders by Positively Regulating the AMPK Signaling Pathway Through the Gut-Liver Axis.
Li P, He X, Feng E, Wei J, Tu H, Chen T
Probiotics and antimicrobial proteins 2025 Feb;17(1):62-80
Probiotics and antimicrobial proteins 2025 Feb;17(1):62-80
Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model.
Li W, Wang X, Chen K, Zhu Y, Yang G, Jin Y, Wang J
Veterinary research 2025 Feb 8;56(1):35
Veterinary research 2025 Feb 8;56(1):35
Transcriptomic analysis of key genes and signaling pathways in sepsis-associated intestinal mucosal barrier damage.
Gao Z, Gong Z, Huang H, Ren X, Li Z, Gao P
Gene 2025 Feb 5;936:149137
Gene 2025 Feb 5;936:149137
Mannuronate Oligosaccharides Ameliorate Experimental Colitis and Secondary Neurological Dysfunction by Manipulating the Gut-Brain Axis.
Lu S, Tao Z, Wang G, Na K, Wu L, Zhang L, Li X, Guo X
Journal of agricultural and food chemistry 2025 Feb 5;73(5):2935-2950
Journal of agricultural and food chemistry 2025 Feb 5;73(5):2935-2950
TRIM37 exacerbates cerebral ischemic injury by regulating the PPARγ/NF-κB pathway.
Shi G, Fu L, Xiao H, Cao F
Neuroreport 2025 Feb 5;36(2):105-115
Neuroreport 2025 Feb 5;36(2):105-115
Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice.
Yang W, Li T, An S, Chen R, Zhao Y, Cui J, Zhang M, Lu J, Tian Y, Bao L, Zhao P
Microbiology spectrum 2025 Feb 4;13(2):e0186124
Microbiology spectrum 2025 Feb 4;13(2):e0186124
Oridonin Preserves Retinal Pigmented Epithelial Cell Tight Junctions and Ameliorates Choroidal Neovascularization.
Zhu J, Ding D, Sun T, Zhang Y, Miao H, Gu Y, Dai M, Zhu M
Investigative ophthalmology & visual science 2025 Feb 3;66(2):56
Investigative ophthalmology & visual science 2025 Feb 3;66(2):56
An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice.
Wang X, Zhang G, Bian Z, Chow V, Grimaldi M, Carivenc C, Sirounian S, Li H, Sladekova L, Motta S, Luperi Y, Gong Y, Costello C, Li L, Jachimowicz M, Guo M, Hu S, Wilson D, Balaguer P, Bourguet W, Mani S, Bonati L, Peng H, March J, Wang H, Wang S, Krause HM, Liu J
Nature communications 2025 Feb 3;16(1):1280
Nature communications 2025 Feb 3;16(1):1280
Lactate-triggered histone lactylation contributes to podocyte epithelial-mesenchymal transition in diabetic nephropathy in mice.
Zheng T, Gu YP, Wang JM, Huang TT, Gou LS, Liu YW
Chemico-biological interactions 2025 Feb 25;408:111418
Chemico-biological interactions 2025 Feb 25;408:111418
HMGB1 mediates epithelial-mesenchymal transition and fibrosis in silicosis via RAGE/β-catenin signaling.
Guo L, Han L, Zhang J, Shen M, Li J, Zhang K, Chen R, Liu H
Chemico-biological interactions 2025 Feb 25;408:111385
Chemico-biological interactions 2025 Feb 25;408:111385
Transcriptomics insights into glutamine on repairing of histamine-induced Yak rumen epithelial cells barrier damage in vitro.
Zhang X, Hu R, Wang Z, Wang J, Yue Z, Wu F, Zhou W, Shah AM
BMC genomics 2025 Feb 25;26(1):195
BMC genomics 2025 Feb 25;26(1):195
Notch/IL33/ST2 signaling was involved in the maintenance of intestinal epithelial barrier through regulating tight junction after LPS stimulation.
Zhang Y, Xu C, Li F, Chen G
Cellular and molecular biology (Noisy-le-Grand, France) 2025 Feb 20;71(2):36-42
Cellular and molecular biology (Noisy-le-Grand, France) 2025 Feb 20;71(2):36-42
House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK/AP-1/IL-24 Signaling pathway in allergic rhinitis.
Zhang S, Wu W, Gu M, Zhao Y, Wang L, Liu K, Yu Z
International immunopharmacology 2025 Feb 20;148:113972
International immunopharmacology 2025 Feb 20;148:113972
NINJ1-mediated plasma membrane rupture of pyroptotic endothelial cells exacerbates blood-brain barrier destruction caused by neutrophil extracellular traps in traumatic brain injury.
Zheng XB, Wang X, Gao SQ, Gao CC, Li T, Han YL, Zhao R, Sun Y, Miao SH, Qiu JY, Jin WX, Zhou ML
Cell death discovery 2025 Feb 20;11(1):69
Cell death discovery 2025 Feb 20;11(1):69
L-Theanine Mitigates Acute Alcoholic Intestinal Injury by Activating the HIF-1 Signaling Pathway to Regulate the TLR4/NF-κB/HIF-1α Axis in Mice.
Tan S, Gu J, Yang J, Dang X, Liu K, Gong Z, Xiao W
Nutrients 2025 Feb 18;17(4)
Nutrients 2025 Feb 18;17(4)
Bioactive nanomotor enabling efficient intestinal barrier penetration for colorectal cancer therapy.
Wang ZH, Zeng X, Huang W, Yang Y, Zhang S, Yang M, Liu H, Zhao F, Li A, Zhang Z, Liu J, Shi J
Nature communications 2025 Feb 16;16(1):1678
Nature communications 2025 Feb 16;16(1):1678
FADS1 inhibition protects retinal pigment epithelium cells from ferroptosis in age related macular degeneration.
Zhang A, Wei TT, Tan X, Tan CY, Zhuang M, Xie TH, Cai J, Yao Y, Zhu L
European journal of pharmacology 2025 Feb 15;989:177227
European journal of pharmacology 2025 Feb 15;989:177227
Treatment of Acute Ulcerative Colitis with Zinc Hyaluronate in Mice.
Zhang L, Fu X, Li J, Xiao W, Xiong X, Lv H, Zhang Z, Ju J
Journal of microbiology and biotechnology 2025 Feb 14;35:e2408050
Journal of microbiology and biotechnology 2025 Feb 14;35:e2408050
Effect of Food Matrix on Regulation of Intestinal Barrier and Microbiota Homeostasis by Polysaccharides Sulfated Carrageenan.
Shang X, Guo J, Chen P
Foods (Basel, Switzerland) 2025 Feb 14;14(4)
Foods (Basel, Switzerland) 2025 Feb 14;14(4)
The bitter flavor of Banxia Xiexin decoction activates TAS2R38 to ameliorate low-grade inflammation in the duodenum of mice with functional dyspepsia.
Ren L, Ruan X, Dong H, Cheng Y, Shon K, Chang C, Gu R, Sun Z
Journal of ethnopharmacology 2025 Feb 11;341:119309
Journal of ethnopharmacology 2025 Feb 11;341:119309
Decreasing β-Catenin Leads to Altered Endothelial Morphology, Increased Barrier Permeability and Cognitive Impairment During Chronic Methamphetamine Exposure.
Qiu H, Zhang M, Chen C, Wang H, Yue X
International journal of molecular sciences 2025 Feb 11;26(4)
International journal of molecular sciences 2025 Feb 11;26(4)
Functional evaluation of novel compound heterozygous variants in SLC12A3 of Gitelman syndrome.
Wang N, Yang Y, Tian X, Fu H, Chen S, Du J, Xu M, He H, Shen B, Xu J
Orphanet journal of rare diseases 2025 Feb 11;20(1):66
Orphanet journal of rare diseases 2025 Feb 11;20(1):66
The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression and after artemisinin treatment.
Chen J, Bai Y, He X, Xiao W, Chen L, Wong YK, Wang C, Gao P, Cheng G, Xu L, Yang C, Liao F, Han G, Sun J, Xu C, Wang J
Nature communications 2025 Feb 11;16(1):1540
Nature communications 2025 Feb 11;16(1):1540
Magnolol preserves the integrity of the intestinal epithelial barrier and mitigates intestinal injury through activation of PPAR γ in COPD rat.
Tao L, Zhang Q, Liu L, Wang K, Liu X, Li J, Zhao P
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119068
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119068
PRDM16 Induces Methylation of FLT3 to Promote FLT3-ITD Signaling and Leukemia Progression.
Zhai F, Pan G, Xue L, Cheng C, Wang J, Liu Y, Liu L
Cancer research 2025 Feb 1;85(3):535-550
Cancer research 2025 Feb 1;85(3):535-550
Polysaccharides from Lycium barbarum, yam, and sunflower ameliorate colitis in a structure and intrinsic flora-dependent manner.
Zhang S, Zhou R, Xie X, Xiong S, Li L, Li Y
Carbohydrate polymers 2025 Feb 1;349(Pt A):122905
Carbohydrate polymers 2025 Feb 1;349(Pt A):122905
Selenoproteome depletion enhances oxidative stress and alters neutrophil functions in Citrobacter rodentium infection leading to gastrointestinal inflammation.
Lee TJ, Liao HC, Salim A, Nettleford SK, Kleinman KL, Carlson BA, Prabhu KS
Free radical biology & medicine 2025 Feb 1;227:499-507
Free radical biology & medicine 2025 Feb 1;227:499-507
Dihydroartemisinin Alleviates Ulcerative Colitis via Target Identification and Pathway Modulation: A Cyberpharmacology Approach.
Zhang Y, Zhao Y, Qin Y, Zhang R, Zhang Z, Zhang Q, Wang J
Biotechnology and applied biochemistry 2025 Dec;72(6):1867-1882
Biotechnology and applied biochemistry 2025 Dec;72(6):1867-1882
Neoagarotetraose Attenuates Hyperglycemia Through Inflammation Amelioration and Glucose Metabolism Improvement.
Cheng J, Yan Q, Liu D, Wu C, Li Y, Jiang Z
Molecular nutrition & food research 2025 Dec;69(24):e70323
Molecular nutrition & food research 2025 Dec;69(24):e70323
Vasoactive intestinal peptide reduces ocular hypertension by regulating tight junction of trabecular meshwork through Rab13/PKA signalling complex.
Chen L, Yan X, Luo Z, Cheng Y, Li M
Annals of medicine 2025 Dec;57(1):2534527
Annals of medicine 2025 Dec;57(1):2534527
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Ma Z, Tu L, Yang X, Mao M, Chen G, Chen F, Liao L, Xu Y
Biochemistry and biophysics reports 2025 Dec;44:102351
Biochemistry and biophysics reports 2025 Dec;44:102351
Activation of the liver X receptor α protects the blood-brain barrier against heatstroke-induced injury.
Li P, Liu X, Luo X, Luo Z, He G, Yang X
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2025 Dec;42(1):2559022
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2025 Dec;42(1):2559022
EUK nanozyme-loaded PL&GA coacervate droplets attenuate ulcerative colitis through restoring gut homeostasis and restricting intestinal cell ferroptosis.
Zhou M, Lu L, Xu X, Zhou Y, Fang H, Wang X, Li D, Li X, Hua J, Liu J, Li Y, Jiang L, Miao Q, Wen H, He J, Yang S
Materials today. Bio 2025 Dec;35:102466
Materials today. Bio 2025 Dec;35:102466
Probiotic-based self-crosslinking bio-coating for the treatment of colitis by increasing probiotic colonization.
Shi S, Li B, Zhang Y, Li Z, Cui Y, Ma C, Zhang X, Liu S, Zhou B
Materials today. Bio 2025 Dec;35:102447
Materials today. Bio 2025 Dec;35:102447
Engineering micelles with hydrophilic-lipophilic balance to overcome intestinal barrier for oral therapeutic application.
Liu K, Zhao P, Chen Y, Zhang Y, Jin J, Wan T
Materials today. Bio 2025 Dec;35:102369
Materials today. Bio 2025 Dec;35:102369
Atractylodin inhibits ferroptosis in sepsis‑induced acute gastrointestinal injury via SIRT3/PRDX3.
Hu YX, Chen MQ, Wang JL, Wu T, Zhang HD, Li TT, Gao H, Bai Y
Molecular medicine reports 2025 Dec;32(6)
Molecular medicine reports 2025 Dec;32(6)
Apelin-13 Attenuates Blood-Brain Barrier Dysfunction Following Intracerebral Hemorrhage via Targeting the Keap1/Nrf2 Signaling.
Guo P, Siddique R, Qian J, Qi L, Yong VW, Xue M
CNS neuroscience & therapeutics 2025 Dec;31(12):e70706
CNS neuroscience & therapeutics 2025 Dec;31(12):e70706
Macrophage extracellular traps impair intestinal barrier function in DSS-induced colitis in mice by inducing intestinal epithelial cell apoptosis.
Zhou Z, Miao X, Shen Y, Wang P, Shi R, Fan H, Yang Y, Guo M, Wu J
Biochemical pharmacology 2025 Dec;242(Pt 3):117406
Biochemical pharmacology 2025 Dec;242(Pt 3):117406
Co-fermentation of honeysuckle-Cassia seeds by Lactobacillus acidophilus and Bacillus subtilis: A new approach to attenuate alcohol-induced acute gastric mucosal damage and modulate immune response.
Zhou M, Cao X, Ji H, Liu Z, Guo H, Zhang Y, Huang Y, Wang F, Pang M, Wei Y
Food research international (Ottawa, Ont.) 2025 Dec;222(Pt 1):117639
Food research international (Ottawa, Ont.) 2025 Dec;222(Pt 1):117639
Nano Zinc Oxide Restores Gut Barrier Integrity and Modulates Microbiota to Mitigate TNBS-Induced Colitis in Mice.
Yu Z, Qiu Y, Yang Y, Wen C, Huang S, Liu T, Zhong R, Peng X
Biological trace element research 2025 Dec;203(12):6213-6224
Biological trace element research 2025 Dec;203(12):6213-6224
Lactobacillus delbrueckii Alleviate Oxidative Stress and Intestinal Injuries by Activating TLR2 and TLR4 Expressions in IPEC-J2 Cells.
Chen F, Wu S, Wang X, Li Y, He B, Fu Y, Huang X, Chen J
Probiotics and antimicrobial proteins 2025 Dec;17(6):5184-5194
Probiotics and antimicrobial proteins 2025 Dec;17(6):5184-5194
Lachnospiraceae bacterium alleviates alcohol-associated liver disease by enhancing N-acetyl-glutamic acid levels and inhibiting ferroptosis through the KEAP1-NRF2 pathway.
Zhang H, Hu Q, Zhang Y, Yang L, Tian S, Zhang X, Shen H, Shu H, Xie L, Wu D, Zhou L, Wei X, Cheng C, Jiang J, Wang H, Shen C, Kong D, Xu L
Gut microbes 2025 Dec;17(1):2517821
Gut microbes 2025 Dec;17(1):2517821
Upregulation of Lactobacillus spp. in gut microbiota as a novel mechanism for environmental eustress-induced anti-pancreatic cancer effects.
Liang Y, Du M, Li X, Gao J, Li Q, Li H, Li J, Gao X, Cong H, Huang Y, Li X, Wang L, Cui J, Gan Y, Tu H
Gut microbes 2025 Dec;17(1):2470372
Gut microbes 2025 Dec;17(1):2470372
Novel role of FTO in regulation of gut-brain communication via Desulfovibrio fairfieldensis-produced hydrogen sulfide under arsenic exposure.
Chen R, Chai X, Zhang Y, Zhou T, Xia Y, Jiang X, Lv B, Zhang J, Zhou L, Tian X, Wang R, Mao L, Zhao F, Zhang H, Hu J, Qiu J, Zou Z, Chen C
Gut microbes 2025 Dec;17(1):2438471
Gut microbes 2025 Dec;17(1):2438471
Neutrophil extracellular trap-borne C3-driven endothelial dysfunction in Klebsiella pneumoniae liver abscess.
Wang H, Chen L, Wang C, Chang Z
Virulence 2025 Dec;16(1):2580104
Virulence 2025 Dec;16(1):2580104
The T-type voltage-gated Ca(2+) channel Ca(V)3.1 involves in the disruption of respiratory epithelial barrier induced by Pasteurella multocida toxin.
Bi H, Wang F, Lin L, Zhang D, Chen M, Shang Y, Hua L, Chen H, Wu B, Peng Z
Virulence 2025 Dec;16(1):2466482
Virulence 2025 Dec;16(1):2466482
Endothelial NLRP3-mediated pyroptosis induces blood-brain barrier and neuronal damage in Huntington's disease models.
Cai J, Ji W, Liu P, Zou L
Journal of pharmacological sciences 2025 Dec;159(4):256-267
Journal of pharmacological sciences 2025 Dec;159(4):256-267
Electroacupuncture Potentiates Astragaloside IV Cerebral Delivery via P-Glycoprotein-Mediated Transcellular Transport: A Novel Blood-Brain Barrier Penetration Strategy for Ischemic Stroke Therapy.
Ouyang L, Yang X, Wu J, Wu B, Huang Q, Chen Y, Zhang X, Cao Y, Chen Y, Yang Y, Zhang J, Hao X, Lu S, Jing X, Fu S
Brain and behavior 2025 Dec;15(12):e71134
Brain and behavior 2025 Dec;15(12):e71134
Shouhui Tongbian capsule promotes calcium absorption by regulating gut microbiota and protects against osteoporosis.
Xu M, Fu Q, Liu J, Chen J, Zhai X, Wang C, Xu W, Li L, Wang K, Si H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157520
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157520
Diacerein attenuates sepsis shock mortality through combined suppression of vascular inflammation, stiffness, and permeability.
Luo M, Jiang Y, Peng Y, Lv D, He A, Huang L, Xia Y, Luo S, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157510
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Dec;149:157510
Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress-Related Male Reproductive Dysfunction.
Zhang L, Gao S, Xiong X, Liu X, Li R, Wang X, Han L, Xiao X, Wang X, Li W, Chang Y, Du Y, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e04817
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e04817
Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2-Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction.
Xu J, Wang Y, Mao W, Wei T, Li Y, Song J, Zhang C, Chen X, Chen C, Xu Q, Wu X, Song Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08725
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08725
Qula-derived Limosilactobacillus fermentum TD-3 and Lactococcus lactis MQ1-1 alleviate aging-related intestinal barrier dysfunction via microbiota-short-chain fatty acid-AMPK/MLCK-tight junction axis.
Liu X, Guan K, Liu C, Sun Y, Ma Y, Mao K, Li Q, Wang R, Lu W
Journal of dairy science 2025 Dec;108(12):12949-12969
Journal of dairy science 2025 Dec;108(12):12949-12969
Nanozymes modulate probiotic tryptophan metabolism to prevent Salmonella infection in mammalian models.
Lin Z, Feng Y, Chen L, Wang J, Wang Q, Cao H, Gao Y, Wang L, Zhang Y, Jiang J, Gao L, Dong B
Nature microbiology 2025 Dec;10(12):3272-3289
Nature microbiology 2025 Dec;10(12):3272-3289
Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer's Disease Agonist of PANK2.
Chen Y, Ma H, Jin M, Zhang S, Qu S, Wang G, Aa J
Pharmaceuticals (Basel, Switzerland) 2025 Dec 9;18(12)
Pharmaceuticals (Basel, Switzerland) 2025 Dec 9;18(12)
Investigating Nickel-Induced Neurotoxicity: Associations with Gut Microbiota Dysbiosis and Ferroptosis.
Shen Y, Cao K, Zhang W, Chen C, Gao C, Wang J, Xin T, Li C, Tang S, Pei X, Li D
Antioxidants (Basel, Switzerland) 2025 Dec 9;14(12)
Antioxidants (Basel, Switzerland) 2025 Dec 9;14(12)
Inflammation-specific DNA origami nanodevice for delivery of siRNAs to treat ulcerative colitis.
Zhang T, Li R, Wang Z, Zhou Y, Zhou Y, Chen X, Peng C, Jiang Y, Tong N, Li W
Nature communications 2025 Dec 8;17(1):495
Nature communications 2025 Dec 8;17(1):495
Recruiting T-cells toward the brain for enhanced glioblastoma chemo-immunotherapy efficacy by co-delivery of cytokines and temozolomide via ultrasound-gated redox-responsive extracellular vesicles.
Dong L, Xu Q, Liu H, Li R, Yun Z, Yang H, Gu Z, Wei J, Guo H, Wei Z, Zhang H
Journal of nanobiotechnology 2025 Dec 7;23(1):766
Journal of nanobiotechnology 2025 Dec 7;23(1):766
Nicotine exacerbates MASH via inducing intestinal dysbiosis and barrier dysfunction.
Yi F, Wang J, Chen Y, Xia Y, Zhou H, Huang Y, Shen Y, Fang S, Wang X, Zhang Y, Chen Y, Chen D
Communications biology 2025 Dec 5;8(1):1748
Communications biology 2025 Dec 5;8(1):1748
Ultra-processed foods sourced 7-ketositosterol aggravates colitis through gut dysbiosis induced-PDLIM3 activation.
Yan J, Pang X, Chen Q, Wang J, Wang Z, Jiao K, Dai Y, Xia T, Jin G, Zhong W, Wang N, Wang B, Zheng J, Xu X, Cao H
Gut microbes 2025 Dec 31;17(1):2587980
Gut microbes 2025 Dec 31;17(1):2587980
CRX is an intrinsic suppressor of epithelial‒mesenchymal transition in retinal pigment epithelial cells: a promising therapeutic avenue for subretinal fibrosis.
Li D, Ou Q, Gao F, Wang X, Zhu L, Zhou Y, Xu JY, Jin C, Wang J, Zhang J, Li J, Bi Y, Lu L, Xu GT, Tian H
Cell death & disease 2025 Dec 31;17(1):156
Cell death & disease 2025 Dec 31;17(1):156
Cigarette smoke-induced lung-brain barrier dysfunction drives neurocognitive impairment via inflammatory spill-over.
Yu X, Xiao H, Bao S, Dong Y, Dong Z, Zhao J, Wang G, Meng X, Wang F
Journal of neuroinflammation 2025 Dec 30;23(1):10
Journal of neuroinflammation 2025 Dec 30;23(1):10
Microbiota-derived indole-3-acetic acid alleviates rumen epithelial barrier dysfunction during the peripartum period through AhR signaling.
Li M, Zhu S, Huo Y, Cao Q, Deng Z, Li K, Li Y, Loor JJ, Wan J, Qi J, Xu C
NPJ biofilms and microbiomes 2025 Dec 30;12(1):32
NPJ biofilms and microbiomes 2025 Dec 30;12(1):32
Atractylenolide III Ameliorates Ulcerative Colitis By Targeting IL-17RA to Suppress Macrophage M1 Polarization.
Shentu C, Mao M, Zhu J, Meng Q, Qian H, Li X, Zhang S, Ding B, Dai S, Yuan X
Journal of agricultural and food chemistry 2025 Dec 3;73(48):30761-30776
Journal of agricultural and food chemistry 2025 Dec 3;73(48):30761-30776
Multi-omics analysis identifies a microbiota-bile acid-TLR signaling axis driving bladder injury in interstitial cystitis.
Peng L, Chen JW, Chen YZ, Di XP, Lin LD, Li BY, Zhang C, Wang W, Gao XS, Ma YC, Shen SH, Li HR, Xu XF, Zeng X, Shen H, Sun Q, Jin T, Luo DY
Nature communications 2025 Dec 29;17(1):1299
Nature communications 2025 Dec 29;17(1):1299
Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections.
Liu Z, Ren P, Xue Y, Liu S, Li S, Li Y, Zhang Y
Clinical science (London, England : 1979) 2025 Dec 23;139(24):1691-1707
Clinical science (London, England : 1979) 2025 Dec 23;139(24):1691-1707
The prevalence of Yersinia enterocolitica in retail pre-prepared dishes in Xi'an and the antibacterial activity and mechanism of ε-polylysine against it.
Wan Y, Li Q, Huang X, Zeng J
International journal of food microbiology 2025 Dec 2;443:111432
International journal of food microbiology 2025 Dec 2;443:111432
Interindividual variability in gut microbiome mediates the efficacy of resistant starch on MASLD.
Long X, Wang H, Lu Y, Gao X, Xiao Y, Zhang M, Guo J, Yang J, Zhang R, Li Q, Zhou G, Yang R, Chen F, Wu Q, Sun L, Chu C, Zhu X, Wu Z, Ren Q, You C, Liu Z, Li Q, Liu D, Cheng D, Kang P, Chen A, Wu Q, Fang Q, Wei L, Zhang L, Li J, Panagiotou G, Jia W, Zeng R, Ni Y, Chen L, Li H
Cell metabolism 2025 Dec 2;37(12):2342-2361.e9
Cell metabolism 2025 Dec 2;37(12):2342-2361.e9
Protocol for the differentiation of induced pluripotent stem cells into retinal pigment epithelial cells.
Zorin M, Ewerling-Hähnel R, Nagel-Wolfrum K
STAR protocols 2025 Dec 19;6(4):104263
STAR protocols 2025 Dec 19;6(4):104263
MRI-DTI contributes to evaluating diffuse neural injury following repetitive mild traumatic brain injury.
Li M, Wang Y, Zhang Z, Gao Y, Chen F, Lei P, Ge X
iScience 2025 Dec 19;28(12):114221
iScience 2025 Dec 19;28(12):114221
Sunitinib Impairs Oral Mucosal Healing Through Endoplasmic Reticulum Stress-Mediated Keratinocyte Dysfunction.
Wang J, Shen L, Chen S, Wang X, He Y, Zhang Y
Cells 2025 Dec 19;15(1)
Cells 2025 Dec 19;15(1)
Alkaline Phosphatase-Triggered Spatiotemporal Repair of Corneal Injury with TB500 Peptide Hydrogel.
Lu P, Shan M, Peng C, Ji W, Yang T, Yang Z, Zhang Z, Wang Y
ACS applied materials & interfaces 2025 Dec 17;17(50):67503-67518
ACS applied materials & interfaces 2025 Dec 17;17(50):67503-67518
Lcn2 from neutrophil extracellular traps induces astrogliosis and post-stroke emotional disorders.
Liu Y, Lin W, Bai Z, Ge Y, Xiao Y, Zhu F, Zhang J, Wang B, Li Q, Gao L, Li Y, Shan C, Nagai J, Wu Y, Xu TL, Gao Z
Neuron 2025 Dec 17;113(24):4199-4216.e8
Neuron 2025 Dec 17;113(24):4199-4216.e8
Alternate-day fasting ameliorates α-synuclein pathology and suppresses inflammation via the gut-brain axis in an MPTP-induced subacute mouse model of Parkinson's disease.
Wang Z, Cui Y, Li D, Yan L, Zhu S, Ma X, Lu Z, Li C, Feng J, Yuan W, He X
NPJ biofilms and microbiomes 2025 Dec 17;11(1):228
NPJ biofilms and microbiomes 2025 Dec 17;11(1):228
Gut microbiome-derived indole-3-carboxaldehyde promotes intestinal development via AHR-NRF2 signaling in the early-life of chicks.
Huang YX, Deng ZC, Cao KX, Yang JC, Liu M, Zhao L, Zheng JS, Sun LH
Microbiome 2025 Dec 16;14(1):34
Microbiome 2025 Dec 16;14(1):34
Clostridium scindens attenuates acute kidney injury by producing indole-3-acetic acid.
Cao YZ, Li JY, Hu JM, Su K, Chen JL, Liu Y, Wei JL, Zhang ZH
NPJ biofilms and microbiomes 2025 Dec 15;12(1):16
NPJ biofilms and microbiomes 2025 Dec 15;12(1):16
A novel long-galanin peptide from non-mammalian vertebrates mitigates the inflammatory response in IBD models via the biased GALR2/β-arrestin2 pathway.
Lai S, Kong X, Xue J, Ma K, Amanullah A, Chen Y, Yang N, Zhang T, Zheng K, Zeng T, Yan X, Zhang C, Kamal S, Ullah N, Luo C, Brosius J, Deng C
Nature communications 2025 Dec 13;16(1):11512
Nature communications 2025 Dec 13;16(1):11512
Nano-functionalized probiotic treats atherosclerosis via inhibiting intestinal microbiota-TMA-TMAO axis.
Chen Z, Zhu Q, Xu H, Hu Y, Wang Y, Chen Z, Wang Y, Huang X, Fu G, Ma B, Zhang W
Nature communications 2025 Dec 13;16(1):11294
Nature communications 2025 Dec 13;16(1):11294
S1PR3 Inhibition in alveolar epithelial cells alleviates pulmonary fibrosis by enhancing alveolar barrier function.
Hao M, Tang G, Zhou E, Fu R, Wang M, Jiang H, Chen X, Bai L, Lv X, Jin J
Respiratory research 2025 Dec 12;27(1):15
Respiratory research 2025 Dec 12;27(1):15
Remimazolam attenuates traumatic brain injury-induced acute lung injury by suppressing pulmonary epithelial pyroptosis.
Sun C, Zhang Y, Wang J, Wang B, Gu A, Wang Y, Gu C
Journal of neuroinflammation 2025 Dec 11;23(1):16
Journal of neuroinflammation 2025 Dec 11;23(1):16
Unique Sertoli cell adaptations support enhanced spermatogenesis in chickens.
Xu G, Gu Z, Wang Z, Zhao J, Ding H, Liu H, Fang Y, Ma X, Guo J, Lyu W, Wang J
Journal of animal science and biotechnology 2025 Dec 10;16(1):170
Journal of animal science and biotechnology 2025 Dec 10;16(1):170
PotD contributes to Streptococcus suis-induced blood-brain barrier disruption by regulating arcA transcription.
Lang S, Yin H, Jia X, Yu X, Meng A, Yan R, Li J, Peng L, Fang R
Veterinary research 2025 Dec 1;57(1):5
Veterinary research 2025 Dec 1;57(1):5
The DRP1 inhibitory peptide P110 provides neuroprotection after subarachnoid hemorrhage by suppressing neuronal apoptosis and stabilizing the blood-brain barrier.
Hao S, Luo J, Yuan S, Chen W, Zhang X, Zhao C, Xu H, Liu Z, Zhang D
Free radical biology & medicine 2025 Dec 1;240:1-14
Free radical biology & medicine 2025 Dec 1;240:1-14
Stroke-Homing Peptide-DNase1 Alleviates Intestinal Ischemia Reperfusion Injury by Selectively Degrading Neutrophil Extracellular Traps.
Liu T, Lv X, Xu Q, Qi X, Qiu S, Luan Y, Shen N, Cheng J, Jin L, Tian T, Liu W, Jin L, Jia Z
Cell proliferation 2025 Aug;58(8):e70010
Cell proliferation 2025 Aug;58(8):e70010
PD-L1 Promotes Immunological Tolerance and Enhances Visual Protection of hESC-RPE Grafts in Retinal Degeneration.
Li B, Zhang X, Fang Y, Chen M, Li Q, Zeng Y, Ren C, Wang C, Lv Y, Lu J, Liu H, Liu Y
Cell proliferation 2025 Aug;58(8):e70007
Cell proliferation 2025 Aug;58(8):e70007
Embryonic exposure to GenX causes reproductive toxicity by disrupting the formation of the blood-testis barrier in mouse offspring.
Fan Z, Hong R, Li S, Kong L, Zhou Q, Ma T, Chen H, Pan C
Toxicology 2025 Aug;515:154161
Toxicology 2025 Aug;515:154161
Glyphosate Induces Anxiety-Like Behaviors in Mice via Activating NLRP3-Mediated Hippocampal Microglia Pyroptosis.
Shu S, Chen X, Ren J, Yu X, Zhang H, Yu Y
Journal of applied toxicology : JAT 2025 Aug;45(8):1572-1582
Journal of applied toxicology : JAT 2025 Aug;45(8):1572-1582
Tannic acid-iron stabilized probiotic silver nano hybrids: Multi-target gut microbiota modulation and intestinal barrier restoration.
Gong S, Zeng Z, Liu M, Wang X, Quan C, Rahim MF, Wang Y, Li A, Kulyar MF, Lu Z, Li J
Materials today. Bio 2025 Aug;33:102106
Materials today. Bio 2025 Aug;33:102106
Yeast β-glucan ameliorated Salmonella-induced gut impairment in broiler chickens by modulating gut microbiome.
Bi R, Abbas W, Li J, Huang J, Hu J, Guo F, Wang Z
International journal of biological macromolecules 2025 Aug;319(Pt 4):145630
International journal of biological macromolecules 2025 Aug;319(Pt 4):145630
Lactoferrin prevents heat stroke-induced intestinal barrier damage by reducing ferroptosis via regulating MAPK signaling pathway: In vitro and in vivo studies.
Li L, Wang Y, Pei Y, Chen J, Zhou J, Gong Y, You J, Cao Y, Chen J, Cai Y, Chang W, Ma J, Ma W, Li X, Song Q, Xu S
International journal of biological macromolecules 2025 Aug;319(Pt 2):145454
International journal of biological macromolecules 2025 Aug;319(Pt 2):145454
Trojan horse strategy and TfR/ LDLR-Mediated transcytosis determine the dissemination of mycobacteria in tuberculous meningoencephalitis.
Liu Z, Wang Y, Dong Y, Wang H, Liang Z, Yue R, Zhou X
Microbiological research 2025 Aug;297:128172
Microbiological research 2025 Aug;297:128172
Targeting CD38 to alleviate brain endothelial cell dysfunction and cognitive impairment in vascular dementia.
Yu M, Qi Z, Zhang J, Zhang Z, Chen J, Yan T, Chen Z
Journal of pharmacological sciences 2025 Aug;158(4):310-321
Journal of pharmacological sciences 2025 Aug;158(4):310-321
Improved prebiotic-based "shield" equipped probiotics for enhanced colon cancer therapy by polarizing M1 macrophages and regulating intestinal microbiota.
Wang Y, Su X, Liu Y, Hu L, Kang L, Xu C, Sun Z, Sun C, Guo H, Shen S
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4225-4247
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4225-4247
Kangquan formula ameliorates the benign prostatic hyperplasia induced by testosterone propionate in rats by regulating urine microecology and metabolic profile.
Li CC, Zeng D, Tang HL, Li XM, Luo YH, Lin J, Xi SY, Wen L, Huang YP
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156931
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Aug;144:156931
Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409-Ube2k-Foxp3 Axis in Regulatory T Cells.
Xie J, Du L, Lu Y, Guo X, Zhou X, Tong Y, Shen B, Yu X, Guo F, Yu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e04214
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(30):e04214
Multiomics Reveals Nonphagocytosable Microplastics Induce Colon Inflammatory Injury via Bile Acid-Gut Microbiota Interactions and Barrier Dysfunction.
Chen J, Cheng Y, Fu R, Chen X, Zhang P, Lu Y, Liu B, Chen P, Wang J, Cao H, Gu J, Chen H, Jiang Z, Li T, Zhang J, Chen B, Cao G
ACS applied materials & interfaces 2025 Aug 6;17(31):44138-44159
ACS applied materials & interfaces 2025 Aug 6;17(31):44138-44159
Apigenin mitigates intestinal barrier dysfunction in sepsis by modulating the AKT signaling pathway.
Lijun Z, Liping W, Dandan Z, Wenjie Z, Renjie X, Xueyan J, Wenqing C, Chen L, Lu Z
BMC gastroenterology 2025 Aug 30;25(1):626
BMC gastroenterology 2025 Aug 30;25(1):626
SPANXB1 drives brain metastasis in breast cancer via MMP1 regulation: potential therapeutic insights with metformin.
Wang Q, Wu H, Zhai Z, Fang D, Yang C, Liu L, Jia X, Du B, Lyu Y, Zhang M, Lu T, Wang L, Gao Y
Cell death discovery 2025 Aug 30;11(1):418
Cell death discovery 2025 Aug 30;11(1):418
Dietary choline deficiency potentiates Helicobacter pylori-driven gut-liver dysfunction via microbial metabolic rewiring.
Li J, Wang L, Meng Z, Ma H, Yu Z, Zhao J, Cui G, Chen Z, Wu D
International immunopharmacology 2025 Aug 28;161:115050
International immunopharmacology 2025 Aug 28;161:115050
Anti-Obesity Effects of Pea Peptides Modified by Steam Explosion on Obese Mice: Regulation of Gut Microbiota and Glucose Metabolism.
Tu J, Liu C, Zhang J, Li T, Zhu J, Wang Q, Wu R, Wang T
Foods (Basel, Switzerland) 2025 Aug 28;14(17)
Foods (Basel, Switzerland) 2025 Aug 28;14(17)
Pediococcus acidilactici GR-5 alleviates hyperuricemia by degrading purine nucleosides and improving gut microbiota metabolism.
Ji J, An ZY, Khan A, Peng L, Kulshreshtha S, Salama ES, Yun H, Liu P, Jin WL, Li X
NPJ science of food 2025 Aug 23;9(1):183
NPJ science of food 2025 Aug 23;9(1):183
Hypoxia disrupts human bronchial epithelial barrier integrity via tight junction protein remodeling and enhanced paracellular leakage.
Huang J, He S, Zhang Q, Liu Y, You Y
European journal of medical research 2025 Aug 23;30(1):794
European journal of medical research 2025 Aug 23;30(1):794
Sanren decoction ameliorates ulcerative colitis by modulating gut microbiota and macrophage polarization to enhance intestinal barrier function.
Zhang S, Li B, Han X, Ruan L, Fu X, Chen Y, Wan H, Zhu X, Liu D, Yi B
Chinese medicine 2025 Aug 20;20(1):128
Chinese medicine 2025 Aug 20;20(1):128
Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics.
Li X, Yan S, Wu X, Miao Q, Zhang D, Mai W, Han S, Tang Z, Ye M, Zhang S, Wei JA, Pan J, Huang D, Qiu S, Zhao Z, Zhong X, Huang M, Qi M, Zhang J, Wang C, Xie J, Wang S, Luo OJ, Zhang D, Ye W, Chen M
Nature communications 2025 Aug 2;16(1):7115
Nature communications 2025 Aug 2;16(1):7115
Kynu inhibition mitigates bile duct ischemic injury by rewiring tryptophan metabolism to restore tight junction integrity.
Bao G, Zhang S, Ye Z, Luo D, Bi P, Yang B
Molecular medicine (Cambridge, Mass.) 2025 Aug 19;31(1):279
Molecular medicine (Cambridge, Mass.) 2025 Aug 19;31(1):279
Taurine alleviated paraquat-induced oxidative stress and gut-liver axis damage in weaned piglets by regulating the Nrf2/Keap1 and TLR4/NF-κB signaling pathways.
Chen C, Qi M, Zhang W, Chen F, Sun Z, Sun W, Tang W, Yang Z, Zhao X, Tang Z
Journal of animal science and biotechnology 2025 Aug 18;16(1):117
Journal of animal science and biotechnology 2025 Aug 18;16(1):117
Oncogenic GOPC-ROS1 fusion promotes the formation of lymphatic malformations by impairing tight junction and its crizotinib resistance through repressing ferroptosis.
Tian R, Weng Z, Liang H, Zhang C, He Q, Li J, Zhang R, Yin X, Deng D, Hong L, Gu S, Zhan Z
Biochemical pharmacology 2025 Aug 15;242(Pt 1):117243
Biochemical pharmacology 2025 Aug 15;242(Pt 1):117243
Flavonoid Extract of Senecio scandens Buch.-Ham. Ameliorates CTX-Induced Immunosuppression and Intestinal Damage via Activating the MyD88-Mediated Nuclear Factor-κB Signaling Pathway.
Zhu X, Zhang L, Ni X, Guo J, Fang Y, Xu J, Chen Z, Hao Z
Nutrients 2025 Aug 1;17(15)
Nutrients 2025 Aug 1;17(15)
Alzheimer's Disease-Derived Outer Membrane Vesicles Exacerbate Cognitive Dysfunction, Modulate the Gut Microbiome, and Increase Neuroinflammation and Amyloid-β Production.
Wei S, Ma X, Chen Y, Wang J, Hu L, Liu Z, Mo L, Zhou N, Chen W, Zhu H, Yan S
Molecular neurobiology 2025 Apr;62(4):5109-5132
Molecular neurobiology 2025 Apr;62(4):5109-5132
Long-Term High-Fat Diet Aggravates Absence Seizures and Neurobehavioral Disorders Without Inducing Metabolic Disorders in WAG/Rij Rats: Involvement of Systemic and Central Inflammation.
Guarnieri L, Bosco F, Ruga S, Tallarico M, Leo A, De Sarro G, Citraro R
Molecular neurobiology 2025 Apr;62(4):4837-4853
Molecular neurobiology 2025 Apr;62(4):4837-4853
Inhibition of C3/C3aR Pathway Alleviates Visual and Optic Nerve Impairments in a Rat Model of Neuromyelitis Optica Spectrum Disorder.
Chen S, Zhang Y, Liu K, Xiao Z, Liu X, Xu Z, Qiu W, Xu Y, Tang C, Yang H
The European journal of neuroscience 2025 Apr;61(8):e70103
The European journal of neuroscience 2025 Apr;61(8):e70103
Engineered brain-targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma.
Yang J, Li Y, Jiang S, Tian Y, Zhang M, Guo S, Wu P, Li J, Xu L, Li W, Wang Y, Gao H, Huang Y, Weng Y, Ruan S
Exploration (Beijing, China) 2025 Apr;5(2):20240039
Exploration (Beijing, China) 2025 Apr;5(2):20240039
Zinc sulfide nanoparticles serve as gas slow-release bioreactors for H(2)S therapy of ischemic stroke.
Li G, Zhang R, Chen K, Dong J, Yang Z, Chen H, Wang H, Wang H, Lei H, Bao W, Zhang M, Xiao Z, Cheng L, Dong Z
Biomaterials 2025 Apr;315:122912
Biomaterials 2025 Apr;315:122912
Androgen deficiency-induced loss of Lactobacillus salivarius extracellular vesicles is associated with the pathogenesis of osteoporosis.
Zhang W, Xie J, Wang Z, Zhong Y, Liu L, Liu J, Zhang W, Pi Y, Tang F, Liu Z, Shao Y, Liu T, Zheng C, Luo J
Microbiological research 2025 Apr;293:128047
Microbiological research 2025 Apr;293:128047
Identification of Cell Fate Determining Transcription Factors for Generating Brain Endothelial Cells.
Ramezankhani R, De Smedt J, Toprakhisar B, van der Veer BK, Tricot T, Vanmarcke G, Balaton B, van Grunsven L, Vosough M, Chai YC, Verfaillie C
Stem cell reviews and reports 2025 Apr;21(3):744-766
Stem cell reviews and reports 2025 Apr;21(3):744-766
In vivo and In vitro assessment of the retinal toxicity of polystyrene nanoplastics.
Zheng J, He L, Shi Q, Wang M, Ma Y, Yu W, Liu L, Yu G, Liu X, Wang B, Zhong J
Environment international 2025 Apr;198:109420
Environment international 2025 Apr;198:109420
Banxia Xiexin Decoction inhibits colitis-associated colorectal cancer development by modulating STAT3 signaling and gut microbiota.
Yue Y, Su L, Wang Y, Li X, Xiao X, Xie J, Yan S
Chinese herbal medicines 2025 Apr;17(2):380-391
Chinese herbal medicines 2025 Apr;17(2):380-391
Microbial metabolite 3-indolepropionic acid alleviated PD pathologies by decreasing enteric glia cell gliosis via suppressing IL-13Rα1 related signaling pathways.
Shang M, Ning J, Zang C, Ma J, Yang Y, Wan Z, Zhao J, Jiang Y, Chen Q, Dong Y, Wang J, Li F, Bao X, Zhang D
Acta pharmaceutica Sinica. B 2025 Apr;15(4):2024-2038
Acta pharmaceutica Sinica. B 2025 Apr;15(4):2024-2038
Thalidomide mitigates Crohn's disease colitis by modulating gut microbiota, metabolites, and regulatory T cell immunity.
Tang CT, Wu Y, Tao Q, Zeng CY, Chen YX
Journal of pharmaceutical analysis 2025 Apr;15(4):101121
Journal of pharmaceutical analysis 2025 Apr;15(4):101121
HMGB1 Encapsulated in Podocyte-Derived Exosomes Plays a Central Role in Glomerular Endothelial Cell Injury in Lupus Nephritis by Regulating TRIM27 Expression.
Liu J, Zhao T, Cui H, Tian Y, Miao X, Xing L, Wang X, Huang J, Liu Q, Zhang W, Shi K, Liu Y, Jia B, Kang L, Tian Y, Yuan W, He S, Feng X, Liu S
Laboratory investigation; a journal of technical methods and pathology 2025 Apr;105(4):104096
Laboratory investigation; a journal of technical methods and pathology 2025 Apr;105(4):104096
Prepubertal Exposure to Tris(2-chloroethyl) Phosphate Disrupts Blood-Testis Barrier Integrity via Ferritinophagy-Mediated Ferroptosis.
Zhao Y, Peng M, Liu H, Zhang X, Fu D
Toxics 2025 Apr 8;13(4)
Toxics 2025 Apr 8;13(4)
Modulation of Intestinal Barrier Function and Wnt/β- Catenin Pathway by Sanzi Formula in Colorectal Adenoma Development.
Peng W, Li Z, Zou S, Li H, Tian Y, Hua Y, Wei L, Zhang Z, Gu Y, Xu T
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(9):547-555
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2025 Apr 7;36(9):547-555
Febrile temperature-regulated TRPV1 in CD4(+) T cells mediates neuroinflammation in complex febrile seizures.
Kong S, Jia X, Liang X, Chen Y, Liang J, Zhang Y, Wu N, Su S, Chen T, He X, Yin J, Han S, Liu W, Fan Y, Xu J, Peng B
Journal of neuroinflammation 2025 Apr 7;22(1):103
Journal of neuroinflammation 2025 Apr 7;22(1):103
Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome.
Zhang Y, Si L, Shu X, Qiu C, Wan X, Li H, Ma S, Jin X, Wei Z, Hu H
Microbiome 2025 Apr 7;13(1):93
Microbiome 2025 Apr 7;13(1):93
Inhibition of CHI3L1 attenuates excessive autophagy in intestinal epithelial cells to reduce the severity of necrotizing enterocolitis.
Li Y, Sun W, Jin X, Li H, Liu X, Bian J, Zhu X
Cell death discovery 2025 Apr 5;11(1):145
Cell death discovery 2025 Apr 5;11(1):145
Distinct roles of A1/A2 astrocytes in blood-brain barrier injury following cerebral I/R via the ROCK/NF-κB and STAT3 pathways.
Geng Z, Deng G, Wang Z, Xu X, Yin X, Zhang S, Shao J, Wen J
International immunopharmacology 2025 Apr 4;151:114338
International immunopharmacology 2025 Apr 4;151:114338
Machine learning-based characterization of PANoptosis-related biomarkers and immune infiltration in ulcerative colitis: A comprehensive bioinformatics analysis and experimental validation.
Wan C, Wu Q, Wang Y, Sun Y, Ji T, Gu Y, Wang L, Chen Q, Yang Z, Wang Y, Wang B, Zhong W
International immunopharmacology 2025 Apr 4;151:114298
International immunopharmacology 2025 Apr 4;151:114298
Podophyllotoxin Alleviates DSS-Induced Ulcerative Colitis via PI3K/AKT Pathway Activation.
Li T, Wang X, Wang J
Physiological research 2025 Apr 30;74(2):287-300
Physiological research 2025 Apr 30;74(2):287-300
Cornua cervi degelatinatum inhibits breast cancer stem-like cell properties and metastasis via miR-148a-3p-mediated TGF-β/Smad2 pathway.
Ma Y, Song B, Peng J, Wei F, Hao Y, Wen Y, Lv H, Shi X, Wang Y, Peng T
Journal of ethnopharmacology 2025 Apr 25;346:119709
Journal of ethnopharmacology 2025 Apr 25;346:119709
Colon-Targeted Mucoadhesive PLGA Microspheres Loaded with Ramulus Mori Alkaloids for Enhanced Water-Soluble Drug Delivery in Ulcerative Colitis Treatment.
Wang M, Jiang Y, Chen Z, Jiang D, Jiang X, Ye J, Wang H, Liu Y
Molecules (Basel, Switzerland) 2025 Apr 23;30(9)
Molecules (Basel, Switzerland) 2025 Apr 23;30(9)
FAM207A acts as a novel and potential biomarker in lung adenocarcinoma and shapes the immunesuppressive tumor microenvironment.
Wang L, Lin F, Yuan J, Wu X, Zhong Y, Li S, Lv Y
Clinical and experimental medicine 2025 Apr 21;25(1):125
Clinical and experimental medicine 2025 Apr 21;25(1):125
Card9 deficiency exacerbates vulvovaginal candidiasis by impairing the IL-17 production and vaginal epithelial barrier.
Liu W, Song Y, Wang R, Wan Z, Li R, Wang X
Medical mycology 2025 Apr 2;63(4)
Medical mycology 2025 Apr 2;63(4)
Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8(+)T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice.
Fan Z, Yi Z, Li S, He J
BMC biotechnology 2025 Apr 16;25(1):30
BMC biotechnology 2025 Apr 16;25(1):30
PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells.
Li X, Liu Q, Wang L, Bu T, Yang X, Gao S, Yun D, Sun F
Molecular and cellular endocrinology 2025 Apr 15;600:112493
Molecular and cellular endocrinology 2025 Apr 15;600:112493
STEAP4 facilitates growth, migration, and invasion of prostate carcinoma through upregulation of NOTCH4.
Fan S, Xia Z, Liu W, Zhu Y, Liu X, Gu P, Cui Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70508
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70508
HFD-induced LPS translocation and elevated blood lipids exacerbated the inflammatory response in allergic rhinitis.
Peng S, Cai X, Tang J, Huang J, Zhao X, Huang X, Li J
Scientific reports 2025 Apr 15;15(1):12931
Scientific reports 2025 Apr 15;15(1):12931
Total ginsenosides from wild ginseng improve immune regulation in a rat model of spleen qi deficiency by modulating fecal-bacteria-associated short-chain fatty acids and intestinal barrier integrity.
Bai R, Ma L, Li F, Pan L, Bao Y, Li X, Wang S, Yue H, Zheng F
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Apr 15;1256:124554
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2025 Apr 15;1256:124554
Statin therapy associated Lactobacillus intestinalis attenuates pancreatic fibrosis through remodeling intestinal homeostasis.
Sui Y, Zhang T, Ou S, Li G, Liu L, Lu T, Zhang C, Cao Y, Bai R, Zhou H, Zhao X, Yuan Y, Wang G, Chen H, Kong R, Sun B, Li L
NPJ biofilms and microbiomes 2025 Apr 15;11(1):59
NPJ biofilms and microbiomes 2025 Apr 15;11(1):59
Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury.
Tian X, Liu B, Li L, Yuan M, You Q, Zhang R, Chen D, Cheng M, Zheng N, He M, Wu Z
Cell communication and signaling : CCS 2025 Apr 14;23(1):183
Cell communication and signaling : CCS 2025 Apr 14;23(1):183
Malus hupehensis leaves: a functional beverage for alleviating hepatic inflammation and modulating gut microbiota in diabetic mice.
Zhang Q, Su T, Pan Y, Wang X, Zhang C, Qin H, Li M, Li Q, Li X, Guo J, Wu L, Qin L, Liu T
Food & function 2025 Apr 14;16(8):2972-2990
Food & function 2025 Apr 14;16(8):2972-2990
Lactobacillus paracasei Expressing Porcine Trefoil Factor 3 and Epidermal Growth Factor: A Novel Approach for Superior Mucosal Repair.
Yin F, Chen Y, Zhang H, Zhao H, Li X, Wang Z, Meng W, Zhao J, Tang L, Li Y, Li J, Wang X
Veterinary sciences 2025 Apr 14;12(4)
Veterinary sciences 2025 Apr 14;12(4)
Proliferator-Activated Receptor Alpha Inhibits Abnormal Extracellular Matrix Accumulation and Maintains Energy Metabolism in Late-Onset Fuchs Endothelial Corneal Dystrophy.
Li X, Liu A, Zhou Y, Qi H, Wang J, Chen M, Sun T, Wu J, Huang Y, Wang L
Investigative ophthalmology & visual science 2025 Apr 1;66(4):36
Investigative ophthalmology & visual science 2025 Apr 1;66(4):36
The role of TFEB-mediated autophagy-lysosome dysfunction in manganese neurotoxicity.
Lu J, Su P, Zhao F, Yu K, Yang X, Lv H, Wang D, Zhang J
Current research in toxicology 2024;7:100193
Current research in toxicology 2024;7:100193
Cell Membrane-Coated Nanotherapeutics for the Targeted Treatment of Acute and Chronic Colitis.
Li S, Chen L, Wu T, Wu J, Yang H, Ju Q, Liu Z, Chen W, Zhang D, Hao Y
Biomaterials research 2024;28:0102
Biomaterials research 2024;28:0102
The Effect Mechanism of N6-adenosine Methylation (m6A) in Melatonin Regulated LPS-induced Colon Inflammation.
Li Y, Ma B, Wang Z, Chen Y, Dong Y
International journal of biological sciences 2024;20(7):2491-2506
International journal of biological sciences 2024;20(7):2491-2506
Chronic Stress-induced Serotonin Impairs Intestinal Epithelial Cell Mitochondrial Biogenesis via the AMPK-PGC-1α Axis.
Yang D, Sun Y, Wen P, Chen Y, Cao J, Sun X, Dong Y
International journal of biological sciences 2024;20(11):4476-4495
International journal of biological sciences 2024;20(11):4476-4495
Therapeutic Effects of Lifei Decoction in a Murine Model of COPD Induced by LPS and Cigarette Smoke.
Lu L, Zhu C, Xu J, Hu Y, Dai J, Wang S, Wei T
International journal of chronic obstructive pulmonary disease 2024;19:957-967
International journal of chronic obstructive pulmonary disease 2024;19:957-967
Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB.
Zhou Y, Xiong X, Cheng Z, Chen Z, Wu S, Yu Y, Liu Y, Chen G, Li L
Drug design, development and therapy 2024;18:4825-4838
Drug design, development and therapy 2024;18:4825-4838
Microbiome-gut-brain axis contributes to patients and Bama miniature pigs with acute large ischemic stroke.
Deng D, Lei H, Cao Z, Zhang C, Du R, Gao X, Wei J, Lu Y, Zhou X, Zhang L
Frontiers in neuroscience 2024;18:1378844
Frontiers in neuroscience 2024;18:1378844
Trimethylamine N-oxide aggravates vascular permeability and endothelial cell dysfunction under diabetic condition: in vitro and in vivo study.
Jiang JY, Liu WM, Zhang QP, Ren H, Yao QY, Liu GQ, Lu PR
International journal of ophthalmology 2024;17(1):25-33
International journal of ophthalmology 2024;17(1):25-33
Fusobacterium Nucleatum Aggravates Intestinal Barrier Impairment and Colitis Through IL-8 Induced Neutrophil Chemotaxis by Activating Epithelial Cells.
Wang Z, Li B, Bao L, Chen Y, Yang J, Xu F, Shi S, Chen W, Wang B, Liu Y
Journal of inflammation research 2024;17:8407-8420
Journal of inflammation research 2024;17:8407-8420
Unleashing AdipoRon's Potential: A Fresh Approach to Tackle Pseudomonas aeruginosa Infections in Bronchiectasis via Sphingosine Metabolism Modulation.
Xu JW, Chen FF, Qv YH, Sun CC, Zhang D, Guo Z, Wang YJ, Wang JF, Liu T, Dong L, Qi Q
Journal of inflammation research 2024;17:7653-7674
Journal of inflammation research 2024;17:7653-7674
The Predictive Value of Serum DAO, HDC, and MMP8 for the Gastrointestinal Injury in the Early Stage of Acute Pancreatitis in an Animal Model and a Clinical Study.
Cheng R, Wang J, Wu Q, Peng P, Liao G, Luo X, Liang Z, Huang J, Qin M
International journal of general medicine 2024;17:1937-1948
International journal of general medicine 2024;17:1937-1948
Lysophosphatidylcholine 14:0 Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Protecting Alveolar Epithelial Barrier by Activation of Nrf2/HO-1 Pathway.
Liu X, Su S, Xia L, Lei X, Zou S, Zhou L, Yang R, Li K, Lin P, Li Y
Journal of inflammation research 2024;17:10533-10546
Journal of inflammation research 2024;17:10533-10546
HucMSC-Ex alleviates DSS-induced colitis in mice by decreasing mast cell activation via the IL-33/ST2 axis.
Wei Z, Tang X, Yi C, Ocansey DKW, Mao F, Mao Z
American journal of translational research 2024;16(6):2727-2744
American journal of translational research 2024;16(6):2727-2744
DNA methylation of miR-181a-5p mediated by DNMT3b drives renal interstitial fibrosis developed from acute kidney injury.
Liu H, Deng Y, Luo G, Yang Y, Xie B, Diao H, Chen M, Chen L, Xie P, Kwan HY, Zhao X, Sun X
Epigenomics 2024;16(13):945-960
Epigenomics 2024;16(13):945-960
Cistanche deserticola polysaccharide alleviates constipation by regulating intestinal barrier function and intestinal microbiota and their metabolites.
Yu Z, Zhang Z, Hu C, Xie L, Zhang R, Gao R, Zhang Z, Wei X, Li T, Guo J
American journal of translational research 2024;16(11):7036-7053
American journal of translational research 2024;16(11):7036-7053
Enriched environment may improve secondary brain injury after traumatic brain injury by regulating the TLR2/NF-κB signaling pathway.
Wu M, He X, Gong Y, Wang C, Huang Y, Gao F, Dang B
Journal of central nervous system disease 2024;16:11795735241301568
Journal of central nervous system disease 2024;16:11795735241301568
Periplanta americana extract regulates the Th17/Treg cell balance via Notch1 in ulcerative colitis.
Zheng Y, Li H, Qi S, Xiao F, Song J, Liu S, Chen X, Li Y, Chen M
Frontiers in pharmacology 2024;15:1534772
Frontiers in pharmacology 2024;15:1534772
Huoxiang Zhengqi dropping pills alleviate exertional heat stroke-induced multiple organ injury through sustaining intestinal homeostasis via regulating MAPK/NF-κB pathway and gut microbiota in rats.
Li L, Ma J, Li Z, Chen J, Zhou J, Wang Y, Pei Y, Gong Y, You J, Cao Y, Wang M, Chen J, Chang W, Ma W, Zhu H, Xiang C, Xu S, Song Q
Frontiers in pharmacology 2024;15:1534713
Frontiers in pharmacology 2024;15:1534713
Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.
Zhu Y, Wang Y, Zuo X, Liu S, Cao L, Wang J, Yang Q, Huang Q, Huang Q, Tian M, Ping Y, Wu Q
Frontiers in immunology 2024;15:1525469
Frontiers in immunology 2024;15:1525469
Polysaccharides derived from golden mushroom (Cantharellus cibarius Fr.) modulate gut microbiota and enhance intestinal barrier function to ameliorate dextran sulfate sodium-induced colitis in mice.
Alioui Y, Ullah H, Ali S, Rahman MU, Elkharti M, Farooqui NA, Rehman AU, Ilyas M, Alsholi DM, Siddiqi NZ, Ali M, Wang L, Xin Y
Frontiers in pharmacology 2024;15:1498625
Frontiers in pharmacology 2024;15:1498625
ABCA1 promote tumor environment heterogeneity via epithelial mesenchymal transition in Huh7 and HepG2 liver cancer cell.
Yu D, Guo F, Zhang Q, Yu H, Wang W, Chen Y
Frontiers in pharmacology 2024;15:1498528
Frontiers in pharmacology 2024;15:1498528
Genome analysis of Bifidobacterium adolescentis and investigation of its effects on inflammation and intestinal barrier function.
Li B, Wang H, Wang M, Liang H, Hu T, Yang J, Li S, You X, Xia B, Yuan Y, Zou Y, Miao Y, Sun Y
Frontiers in microbiology 2024;15:1496280
Frontiers in microbiology 2024;15:1496280
Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosis.
Wang C, Wang W, Dong J, Li X, Ye T, Zeng F, Jiang M, Shi J, Wang X, Zhang L
Frontiers in pharmacology 2024;15:1489956
Frontiers in pharmacology 2024;15:1489956
Scutellarein ameliorates dextran sulfate sodium-induced ulcerative colitis by inhibiting colonic epithelial cell proinflammation and barrier disruption.
Tang Q, Jia H, Qin X, Lu Z, Huang W, Wang Y, Cao Z
Frontiers in pharmacology 2024;15:1479441
Frontiers in pharmacology 2024;15:1479441
GYY4137, as a slow-releasing H(2)S donor, ameliorates sodium deoxycholate-induced chronic intestinal barrier injury and gut microbiota dysbiosis.
Pan S, Yan H, Zhu J, Ma Y, Wang P, Liu Y, Chen Z
Frontiers in pharmacology 2024;15:1476407
Frontiers in pharmacology 2024;15:1476407
Hyperbaric oxygen-induced acute lung injury: A mouse model study on pathogenic characteristics and recovery dynamics.
Wang S, Chen H, Li Z, Xu G, Bao X
Frontiers in physiology 2024;15:1474933
Frontiers in physiology 2024;15:1474933
Matrine regulates autophagy in ileal epithelial cells in a porcine circovirus type 2-infected murine model.
Wang H, Sun N, Sun P, Zhang H, Yin W, Zheng X, Fan K, Sun Y, Li H
Frontiers in microbiology 2024;15:1455049
Frontiers in microbiology 2024;15:1455049
Gasdermin D could be lost in the brain parenchyma infarct core and a pyroptosis-autophagy inhibition effect of Jie-Du-Huo-Xue decoction after stroke.
Zhou C, Qiu SW, Wang FM, Liu YC, Hu W, Yang ML, Liu WH, Li H
Frontiers in pharmacology 2024;15:1449452
Frontiers in pharmacology 2024;15:1449452
Different effects of acute and chronic oxidative stress on the intestinal flora and gut-liver axis in weaned piglets.
Zhang H, Xiang X, Wang C, Li T, Xiao X, He L
Frontiers in microbiology 2024;15:1414486
Frontiers in microbiology 2024;15:1414486
Effects of the ACE2-Ang-(1-7)-Mas axis on gut flora diversity and intestinal metabolites in SuHx mice.
Abudukeremu A, Aikemu A, Yang T, Fang L, Aihemaitituoheti A, Zhang Y, Shanahaiti D, Nijiati Y
Frontiers in microbiology 2024;15:1412502
Frontiers in microbiology 2024;15:1412502
Circadian rhythm disruption-mediated downregulation of Bmal1 exacerbates DSS-induced colitis by impairing intestinal barrier.
Zhang Z, Li W, Han X, Tian D, Yan W, Liu M, Cao L
Frontiers in immunology 2024;15:1402395
Frontiers in immunology 2024;15:1402395
Thonningianin A ameliorated renal interstitial fibrosis in diabetic nephropathy mice by modulating gut microbiota dysbiosis and repressing inflammation.
Zhang S, Zhang S, Bai X, Wang Y, Liu Y, Liu W
Frontiers in pharmacology 2024;15:1389654
Frontiers in pharmacology 2024;15:1389654
TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway.
Zhao J, Chen C, Ge L, Jiang Z, Hu Z, Yin L
Frontiers in immunology 2024;15:1386780
Frontiers in immunology 2024;15:1386780
Heat acclimation with probiotics-based ORS supplementation alleviates heat stroke-induced multiple organ dysfunction via improving intestinal thermotolerance and modulating gut microbiota in rats.
Li L, Chen J, Wang Y, Pei Y, Ren L, Dai X, Li J, Ma J, Wang M, Chang W, Chen J, Song Q, Xu S
Frontiers in microbiology 2024;15:1385333
Frontiers in microbiology 2024;15:1385333
Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation.
Yang X, He Z, Dong Q, Nai S, Duan X, Yu J, Zhao N, Du X, Chen L
Frontiers in immunology 2024;15:1382661
Frontiers in immunology 2024;15:1382661
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
He C, An Y, Shi L, Huang Y, Zhang H, Fu W, Wang M, Shan Z, Du Y, Xie J, Huang Z, Sun W, Zhao Y, Zhao B
Frontiers in pharmacology 2024;15:1371929
Frontiers in pharmacology 2024;15:1371929
Quercetin ameliorates ulcerative colitis by restoring the balance of M2/M1 and repairing the intestinal barrier via downregulating cGAS‒STING pathway.
Gao F, Zhu F, Shuai B, Wu M, Wei C, Yuan Y, Gui Y, Tian Y, Fan H, Wu H
Frontiers in pharmacology 2024;15:1351538
Frontiers in pharmacology 2024;15:1351538
SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.
Luo Y, Zhang Z, Ren J, Dou C, Wen J, Yang Y, Li X, Yan Z, Han Y
Frontiers in immunology 2024;15:1303356
Frontiers in immunology 2024;15:1303356
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Wang Y, Bai Y, Cai Y, Zhang Y, Shen L, Xi W, Zhou Z, Xu L, Liu X, Han B, Yao H
Theranostics 2024;14(19):7292-7308
Theranostics 2024;14(19):7292-7308
Interaction of Neisseria meningitidis carrier and disease isolates of MenB cc32 and MenW cc22 with epithelial cells of the nasopharyngeal barrier.
Peters S, Mohort K, Claus H, Stigloher C, Schubert-Unkmeir A
Frontiers in cellular and infection microbiology 2024;14:1389527
Frontiers in cellular and infection microbiology 2024;14:1389527
Nocardia rubra cell-wall skeleton mitigates whole abdominal irradiation-induced intestinal injury via regulating macrophage function.
Wu L, Chen L, Li H, Wang Y, Xu K, Chen W, Zhang A, Wang Y, Shi C
Burns & trauma 2024;12:tkad045
Burns & trauma 2024;12:tkad045
In vitro co-culture of Clostridium scindens with primary human colonic epithelium protects the epithelium against Staphylococcus aureus.
Wang H, Kim R, Wang Y, Furtado KL, Sims CE, Tamayo R, Allbritton NL
Frontiers in bioengineering and biotechnology 2024;12:1382389
Frontiers in bioengineering and biotechnology 2024;12:1382389
Propionate-producing engineered probiotics ameliorated murine ulcerative colitis by restoring anti-inflammatory macrophage via the GPR43/HDAC1/IL-10 axis.
Kang G, Wang X, Gao M, Wang L, Feng Z, Meng S, Wu J, Zhu Z, Gao X, Cao X, Huang H
Bioengineering & translational medicine 2024 Sep;9(5):e10682
Bioengineering & translational medicine 2024 Sep;9(5):e10682
Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway.
Li YX, Liu J, Li F
Cell biochemistry and biophysics 2024 Sep;82(3):2747-2757
Cell biochemistry and biophysics 2024 Sep;82(3):2747-2757
1,25-Dihydroxyvitamin D3 reduces early mortality post severe burn injury via alleviating endotoxemia, oxidative stress and inflammation.
Chen Y, Guo JH, Chen YJ, Huang Y, Zhang C, Zhang Q, Gong YL, Chen J
Burns : journal of the International Society for Burn Injuries 2024 Sep;50(7):1790-1798
Burns : journal of the International Society for Burn Injuries 2024 Sep;50(7):1790-1798
Blueberry extract for the treatment of ischaemic stroke through regulating the gut microbiota and kynurenine metabolism.
Wang R, Huang G, Li S, Huang H, Zhu G, Wang L, Yang J, Yang S, Jiang Z, Zhang W
Phytotherapy research : PTR 2024 Sep;38(9):4792-4814
Phytotherapy research : PTR 2024 Sep;38(9):4792-4814
Esculentoside H reduces the PANoptosis and protects the blood-brain barrier after cerebral ischemia/reperfusion through the TLE1/PI3K/AKT signaling pathway.
Zhang K, Wang ZC, Sun H, Long H, Wang Y
Experimental neurology 2024 Sep;379:114850
Experimental neurology 2024 Sep;379:114850
4-methylimidazole exposure impairs sperm mobility by reducing the expression of blood-testis barrier junction protein in mouse testes.
Lu Y, Ma W, Tang H, Wu X, Yang X, Sun F
Reproductive biology 2024 Sep;24(3):100928
Reproductive biology 2024 Sep;24(3):100928
Lactobacillus gasseri ATCC33323 affects the intestinal mucosal barrier to ameliorate DSS-induced colitis through the NR1I3-mediated regulation of E-cadherin.
Qian G, Zang H, Tang J, Zhang H, Yu J, Jia H, Zhang X, Zhou J
PLoS pathogens 2024 Sep;20(9):e1012541
PLoS pathogens 2024 Sep;20(9):e1012541
Carbon monoxide-releasing molecule-3 exerts neuroprotection effects after cardiac arrest in mice: A randomized controlled study.
Zhao Y, Yao Z, Lu L, Xu S, Sun J, Zhu Y, Wu Y, Yu Z
Resuscitation plus 2024 Sep;19:100703
Resuscitation plus 2024 Sep;19:100703
Plant essential oils combined with organic acids restored lipopolysaccharide-induced leaky intestine via gut microbial modulation in weaned piglets.
Zheng X, Wang Y, Zhou X, Deng T, Zhao Y, Fu Z, Wei Y, Ma W, Zhang S, Guan W, Chen F
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Sep;18:419-432
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Sep;18:419-432
Icariin alleviates oxygen-induced retinopathy by targeting microglia hexokinase 2.
Li X, Wang G, Li N, Wang X, Fan W, Zhang Z, Li W, Liu J, Huang J, Liu X, Zhou Q, Hou S
Immunology 2024 Sep;173(1):141-151
Immunology 2024 Sep;173(1):141-151
MMP-2-mediated Scube2 degradation promotes blood-brain barrier disruption by blocking the interaction between astrocytes and endothelial cells via inhibiting Sonic hedgehog pathway during early cerebral ischemia.
Shi T, Yue S, Xie C, Li X, Yang D, Hu L, Zhong Y, Zhang Y, Liu W
Journal of neurochemistry 2024 Sep;168(9):1877-1894
Journal of neurochemistry 2024 Sep;168(9):1877-1894
Cinnamaldehyde alleviates aspirin-induced gastric mucosal injury by regulating pi3k/akt pathway-mediated apoptosis, autophagy and ferroptosis.
Yan S, Bao S, Chen T, Chen J, Zhang J, Hu X, Liang Y, Zhou X, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155791
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155791
Microbial Tryptophan Metabolites Ameliorate Ovariectomy-Induced Bone Loss by Repairing Intestinal AhR-Mediated Gut-Bone Signaling Pathway.
Chen C, Cao Z, Lei H, Zhang C, Wu M, Huang S, Li X, Xie D, Liu M, Zhang L, Chen G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2404545
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(36):e2404545
Intestinal NSD2 Aggravates Nonalcoholic Steatohepatitis Through Histone Modifications.
Zhang Y, Qiao Y, Li Z, Liu D, Jin Q, Guo J, Li X, Chen L, Liu L, Peng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402551
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402551
Berberine and magnolol exert cooperative effects on ulcerative colitis in mice by self-assembling into carrier-free nanostructures.
Xu Y, Chen Z, Hao W, Yang Z, Farag M, Vong CT, Wang Y, Wang S
Journal of nanobiotechnology 2024 Sep 4;22(1):538
Journal of nanobiotechnology 2024 Sep 4;22(1):538
Ternary inulin hydrogel with long-term intestinal retention for simultaneously reversing IBD and its fibrotic complication.
Cao X, Tao S, Wang W, Wu S, Hong Y, Wang X, Ma Y, Qian H, Zha Z
Nature communications 2024 Sep 28;15(1):8428
Nature communications 2024 Sep 28;15(1):8428
Esculetin Combats Multidrug-Resistant Salmonella Infection and Ameliorates Intestinal Dysfunction via the Nrf2 Pathway.
Xu W, Ding W, Jia L, Zhu K, Luo Q
Antioxidants (Basel, Switzerland) 2024 Sep 26;13(10)
Antioxidants (Basel, Switzerland) 2024 Sep 26;13(10)
SARS-CoV-2 ORF3a Protein Impairs Syncytiotrophoblast Maturation, Alters ZO-1 Localization, and Shifts Autophagic Pathways in Trophoblast Cells and 3D Organoids.
Kumar D, Karvas RM, Jones BR, McColl ER, Diveley E, Sukanta J, Surendra S, Kelly JC, Theunissen TW, Mysorekar IU
bioRxiv : the preprint server for biology 2024 Sep 25;
bioRxiv : the preprint server for biology 2024 Sep 25;
Disulfiram attenuates cell and tissue damage and blood‒brain barrier dysfunction after intracranial haemorrhage by inhibiting the classical pyroptosis pathway.
Xu C, Jiang F, Mao Y, Wei W, Song J, Jia F, Du X, Zhong D, Li G
Scientific reports 2024 Sep 19;14(1):21860
Scientific reports 2024 Sep 19;14(1):21860
Neohesperidin Attenuates DSS-Induced Ulcerative Colitis by Inhibiting Inflammation, Reducing Intestinal Barrier Damage, and Modulating Intestinal Flora Composition.
Ju T, Song Z, Qin D, Cheng J, Li T, Hu G, Fu S
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20419-20431
Journal of agricultural and food chemistry 2024 Sep 18;72(37):20419-20431
Allantoin ameliorates dopaminergic neuronal damage in MPTP-induced Parkinson's disease mice via regulating oxidative damage, inflammation, and gut microbiota disorder.
Yang S, Sun X, Liu D, Zhang Y, Gao X, He J, Cui M, Fu S, He D
Food & function 2024 Sep 16;15(18):9390-9408
Food & function 2024 Sep 16;15(18):9390-9408
Procyanidin B1 and p-coumaric acid from whole highland barley ameliorated HFD-induced impaired glucose tolerance via small intestinal barrier and hepatic glucose metabolism.
Liu Z, Yang Y, Xu Y, Zhang Z, Tang R, Liu J, Jiang H, Zhao R
Food & function 2024 Sep 16;15(18):9272-9283
Food & function 2024 Sep 16;15(18):9272-9283
Ginsenoside compound K alleviates D-galactose-induced mild cognitive impairment by modulating gut microbiota-mediated short-chain fatty acid metabolism.
Yan X, Bai X, Fu R, Duan Z, Zeng W, Zhu C
Food & function 2024 Sep 16;15(18):9037-9052
Food & function 2024 Sep 16;15(18):9037-9052
TJP1 suppresses trophoblast cell invasion by expressing E2F8 in the human placenta.
Miki R, Matsuo S, Ushida T, Tano S, Imai K, Nawa A, Kajiyama H, Kotani T
Molecular and cellular endocrinology 2024 Sep 15;591:112277
Molecular and cellular endocrinology 2024 Sep 15;591:112277
Zinc oxide nanoparticles disrupt the mammary epithelial barrier via Z-DNA binding protein 1-triggered PANoptosis.
Zhu Z, Zhang Y, Wang R, Dong Y, Wu J, Shao L
Ecotoxicology and environmental safety 2024 Sep 15;283:116777
Ecotoxicology and environmental safety 2024 Sep 15;283:116777
Oral administration of tea-derived exosome-like nanoparticles protects epithelial and immune barrier of intestine from psychological stress.
Gong Q, Sun Y, Liu L, Pu C, Guo Y
Heliyon 2024 Sep 15;10(17):e36812
Heliyon 2024 Sep 15;10(17):e36812
Integrating metagenomics with metabolomics for gut microbiota and metabolites profiling in acute pancreatitis.
Jia Y, Shi Y, Wang J, Liu H, Huang Y, Wang H, Liu Y, Peng J
Scientific reports 2024 Sep 14;14(1):21491
Scientific reports 2024 Sep 14;14(1):21491
ROS exhaustion reverses the effects of hyperbaric oxygen on hemorrhagic transformation through reactivating microglia in post-stroke hyperglycemic mice.
Guo Y, Liu J, Du X, Qi M, She T, Xue K, Wu X, Xu L, Peng B, Zhang Y, Liu Y, Jiang Z, Li X, Yuan Y
Scientific reports 2024 Sep 13;14(1):21410
Scientific reports 2024 Sep 13;14(1):21410
Protection of blood-brain barrier by endothelial DAPK1 deletion after stroke.
Gu Z, Li S, Liu J, Zhang X, Pang C, Ding L, Cao C
Biochemical and biophysical research communications 2024 Sep 10;724:150216
Biochemical and biophysical research communications 2024 Sep 10;724:150216
IL-37 protects against house dust mite-induced airway inflammation and airway epithelial barrier dysfunction via inhibiting store-operated calcium entry.
Wang C, Zhong J, Hu J, Cao C, Qi S, Ma R, Fu W, Zhang X, Akdis CA, Gao Y
International immunopharmacology 2024 Sep 10;138:112525
International immunopharmacology 2024 Sep 10;138:112525
Gut microbiota dysbiosis contributes to α-synuclein-related pathology associated with C/EBPβ/AEP signaling activation in a mouse model of Parkinson's disease.
Fang X, Liu S, Muhammad B, Zheng M, Ge X, Xu Y, Kan S, Zhang Y, Yu Y, Zheng K, Geng D, Liu CF
Neural regeneration research 2024 Sep 1;19(9):2081-2088
Neural regeneration research 2024 Sep 1;19(9):2081-2088
Neuroprotection of Human Umbilical Cord-Derived Mesenchymal Stem Cells (hUC-MSCs) in Alleviating Ischemic Stroke-Induced Brain Injury by Regulating Inflammation and Oxidative Stress.
Liu G, Wang D, Jia J, Hao C, Ge Q, Xu L, Zhang C, Li X, Mi Y, Wang H, Miao L, Chen Y, Zhou J, Xu X, Liu Y
Neurochemical research 2024 Oct;49(10):2871-2887
Neurochemical research 2024 Oct;49(10):2871-2887
Streptococcus salivarius ameliorates the destructive effect on the epithelial barrier by inhibiting the growth of Prevotella melaninogenica via metabolic acid production.
Zhu P, Shao R, Xu P, Zhao R, Zhao C, Fei J, He Y
Molecular oral microbiology 2024 Oct;39(5):407-416
Molecular oral microbiology 2024 Oct;39(5):407-416
Protective properties of Ophiopogonin D in DSS-induced colitis: insights into microbiota modulation.
Zhang T, Guo Z, Cheng X, Xia R, Lai S, Liao L
Inflammopharmacology 2024 Oct;32(5):3553-3570
Inflammopharmacology 2024 Oct;32(5):3553-3570
Linagliptin's impact on lymphatic barrier and lymphangiogenesis in oral cancer with high glucose.
Wang H, She X, Xu Q, Zhou X, Tang Q, Wei H, Huang T, Liang F
Oral diseases 2024 Oct;30(7):4195-4208
Oral diseases 2024 Oct;30(7):4195-4208
Immortalized mesenchymal stromal cells overexpressing alpha-1 antitrypsin protect acinar cells from apoptotic and ferroptotic cell death.
Shoeibi S, Green E, Wei H, Gou W, Strange C, Wang H
Journal of cellular and molecular medicine 2024 Oct;28(20):e70093
Journal of cellular and molecular medicine 2024 Oct;28(20):e70093
Epicatechin and β-glucan from whole highland barley grain ameliorates hyperlipidemia associated with attenuating intestinal barrier dysfunction and modulating gut microbiota in high-fat-diet-fed mice.
Liu Z, Tang R, Liu J, Zhang Z, Li Y, Zhao R
International journal of biological macromolecules 2024 Oct;278(Pt 3):134917
International journal of biological macromolecules 2024 Oct;278(Pt 3):134917
Multi-omics insights into anti-colitis benefits of the synbiotic and postbiotic derived from wheat bran arabinoxylan and Limosilactobacillus reuteri.
Zhou L, Song W, Liu T, Yan T, He Z, He W, Lv J, Zhang S, Dai X, Yuan L, Shi L
International journal of biological macromolecules 2024 Oct;278(Pt 3):134860
International journal of biological macromolecules 2024 Oct;278(Pt 3):134860
Abelmoschi Corolla polysaccharides and related metabolite ameliorates colitis via modulating gut microbiota and regulating the FXR/STAT3 signaling pathway.
He L, Chen K, Chen Z, Chen C, Zhou J, Shao Y, Ma J, Qiu Z, Chen Y, Zhang W
International journal of biological macromolecules 2024 Oct;277(Pt 3):134370
International journal of biological macromolecules 2024 Oct;277(Pt 3):134370
Combined effects of TiO(2) nanoparticle and fipronil co-exposure on microbiota in mouse intestine.
Wang C, Liu Y, He Y, Li J, Cao Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114931
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Oct;192:114931
PPARγ/NF-κB axis contributes to cold-induced resolution of experimental colitis and preservation of intestinal barrier.
Di Y, Li H, Yang J, Feng M, Wang S, Li W, Wang X, Zhu Y, Shi Y, Feng R, Qu B
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167326
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167326
Cdk1/p53/p21 feedback loop mechanisms in the pathogenesis of interstitial cystitis/bladder pain syndrome.
Wang K, Shi J, Chen Z, Xue D, He X
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167305
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167305
Corilagin alleviates ferroptosis in diabetic retinopathy by activating the Nrf2 signaling pathway.
Shi W, Dong Y, Liu S, Li F, Zhu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117409
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Oct;179:117409
Galangin Alleviates Alcohol-Provoked Liver Injury Associated with Gut Microbiota Disorder and Intestinal Barrier Dysfunction in Mice.
Zhao Y, Li B, Deng H, Zhang C, Wang Y, Chen L, Teng H
Journal of agricultural and food chemistry 2024 Oct 9;72(40):22336-22348
Journal of agricultural and food chemistry 2024 Oct 9;72(40):22336-22348
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
Niu R, Lan J, Liang D, Xiang L, Wu J, Zhang X, Li Z, Chen H, Geng L, Xu W, Gong S, Yang M
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
ENDOTHELIAL PROX1 INDUCES BLOOD-BRAIN BARRIER DISRUPTION IN THE CENTRAL NERVOUS SYSTEM.
González-Hernández S, Sato R, Sato Y, Liu C, Li W, Liu C, Jackson S, Kubota Y, Mukouyama YS
bioRxiv : the preprint server for biology 2024 Oct 4;
bioRxiv : the preprint server for biology 2024 Oct 4;
Kiwifruit Polysaccharides Alleviate Ulcerative Colitis via Regulating Gut Microbiota-Dependent Tryptophan Metabolism and Promoting Colon Fucosylation.
Li Y, Han Y, Wang X, Yang X, Ren D
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23859-23874
Journal of agricultural and food chemistry 2024 Oct 30;72(43):23859-23874
Neurons enhance blood-brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion.
Yang L, Lin Z, Mu R, Wu W, Zhi H, Liu X, Yang H, Liu L
eLife 2024 Oct 30;13
eLife 2024 Oct 30;13
Anemarrhena asphodeloides Bunge polysaccharides alleviate lipoteichoic acid-induced lung inflammation and modulate gut microbiota in mice.
Wen Y, Ullah H, Ma R, Farooqui NA, Li J, Alioui Y, Qiu J
Heliyon 2024 Oct 30;10(20):e39390
Heliyon 2024 Oct 30;10(20):e39390
Gut Lactococcus garvieae promotes protective immunity to foodborne Clostridium perfringens infection.
Wang X-Y, Meng F-H, Zhang M-Y, Li F-X, Lei Y-X, Ma Z-G, Li J-Q, Lou Y-N, Chu Y-F, Ma K, Yu S-X
Microbiology spectrum 2024 Oct 3;12(10):e0402523
Microbiology spectrum 2024 Oct 3;12(10):e0402523
Human breast milk-derived phospholipid DOPE ameliorates intestinal injury associated with NEC by inhibiting ferroptosis.
Chen Y, Chen W, Dai Y, Yan X, Jiang C, Zhang F, Zhang M, Hu X, Zhao J, Wu T, Li S, Han S, Chen X
Food & function 2024 Oct 28;15(21):10811-10822
Food & function 2024 Oct 28;15(21):10811-10822
Targeted Delivery of Celastrol by GA-Modified Liposomal Calcium Carbonate Nanoparticles to Enhance Antitumor Efficacy Against Breast Cancer.
Zhang W, Li J, Yue L, Ji C
Pharmaceutics 2024 Oct 27;16(11)
Pharmaceutics 2024 Oct 27;16(11)
DHA-enriched phosphatidylserine ameliorates cyclophosphamide-induced liver injury via regulating the gut-liver axis.
Zhang H, Lu Y, Zhang Y, Dong J, Jiang S, Tang Y
International immunopharmacology 2024 Oct 25;140:112895
International immunopharmacology 2024 Oct 25;140:112895
Morin alleviates DSS-induced ulcerative colitis in mice via inhibition of inflammation and modulation of intestinal microbiota.
Qiu L, Yan C, Yang Y, Liu K, Yin Y, Zhang Y, Lei Y, Jia X, Li G
International immunopharmacology 2024 Oct 25;140:112846
International immunopharmacology 2024 Oct 25;140:112846
Goat Milk Exosomes Ameliorate Ulcerative Colitis in Mice through Modulation of the Intestinal Barrier, Gut Microbiota, and Metabolites.
Gao F, Wu S, Zhang K, Xu Z, Zhang X, Zhu Z, Quan F
Journal of agricultural and food chemistry 2024 Oct 23;72(42):23196-23210
Journal of agricultural and food chemistry 2024 Oct 23;72(42):23196-23210
WIF-1 contributes to lupus-induced neuropsychological deficits via the CRYAB/STAT4-SHH axis.
Tan L, Fan Y, Xu X, Zhang T, Cao X, Zhang C, Liang J, Hou Y, Dou H
Arthritis research & therapy 2024 Oct 23;26(1):183
Arthritis research & therapy 2024 Oct 23;26(1):183
eIF6 deficiency regulates gut microbiota, decreases systemic inflammation, and alleviates atherosclerosis.
Wang Z, Yang S, Tong L, Li X, Mao W, Yuan H, Chen Y, Zhang S, Zhang H, Chen R
mSystems 2024 Oct 22;9(10):e0059524
mSystems 2024 Oct 22;9(10):e0059524
Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling.
Zhang G, Liang Z, Wang Y, Zhang Z, Hoi PM
Antioxidants (Basel, Switzerland) 2024 Oct 21;13(10)
Antioxidants (Basel, Switzerland) 2024 Oct 21;13(10)
Therapeutic Potential of Foodborne Indole Derived from Chinese Stinky Tofu in Reducing Intestinal Inflammation and Enhancing Barrier Function to Mitigate Alcoholic Liver Injury.
Peng Q, Zheng H, Quan L, Li S, Huang J, Li J, Xie G
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21829-21842
Journal of agricultural and food chemistry 2024 Oct 2;72(39):21829-21842
Identification of COL3A1 as a candidate protein involved in the crosstalk between obesity and diarrhea using quantitative proteomics and machine learning.
Wang Y, Wang X, Niu X, Han K, Ru N, Xiang J, Linghu E
European journal of pharmacology 2024 Oct 15;981:176881
European journal of pharmacology 2024 Oct 15;981:176881
Intermittent fasting attenuates cognitive dysfunction and systemic disease activity in mice with neuropsychiatric systemic lupus erythematosus.
Feng Y, Qin J, Wang P, Lai Y, Tang L, Zhang X, Ren H, Yang M, Huang Q
Life sciences 2024 Oct 15;355:122999
Life sciences 2024 Oct 15;355:122999
Alterations in microbiota-metabolism-circRNA crosstalk in autism spectrum disorder-like behaviours caused by maternal exposure to glyphosate-based herbicides in mice.
He X, Yang Y, Zhou S, Wei Q, Zhou H, Tao J, Yang G, You M
Ecotoxicology and environmental safety 2024 Oct 15;285:117060
Ecotoxicology and environmental safety 2024 Oct 15;285:117060
NF-κB pathway activation by Octopus peptide hydrolysate ameliorates gut dysbiosis and enhances immune response in cyclophosphamide-induced mice.
Ali M, Ullah H, Farooqui NA, Deng T, Siddiqui NZ, Ilyas M, Ali S, Rahman MU, Rehman AU, Alioui Y, Wang L, Yi X
Heliyon 2024 Oct 15;10(19):e38370
Heliyon 2024 Oct 15;10(19):e38370
Cadmium Induces Vascular Endothelial Cell Detachment by Downregulating Claudin-5 and ZO-1 Levels.
Hara T, Asatsu M, Yamagishi T, Ohata C, Funatsu H, Takahashi Y, Shirai M, Nakata C, Katayama H, Kaji T, Fujie T, Yamamoto C
International journal of molecular sciences 2024 Oct 14;25(20)
International journal of molecular sciences 2024 Oct 14;25(20)
Gut microbiome and metabolites mediate the benefits of caloric restriction in mice after acute kidney injury.
Zhu XX, Fu X, Meng XY, Su JB, Zheng GL, Xu AJ, Chen G, Zhang Y, Liu Y, Hou XH, Qiu HB, Sun QY, Hu JY, Lv ZL, Wang Y, Jiang HB, Bao N, Han ZJ, Lu QB, Sun HJ
Redox biology 2024 Nov;77:103373
Redox biology 2024 Nov;77:103373
Reduced Proline-Rich Tyrosine Kinase 2 Promotes Tumor Metastasis by Activating Epithelial-Mesenchymal Transition in Colorectal Cancer.
Wu F, Zhang K, Song Z, Zhou Q, Sun H, Tan Z, Huang Z, Wang F, Wang Z, Yang R, Huang Y
Digestive diseases and sciences 2024 Nov;69(11):4098-4107
Digestive diseases and sciences 2024 Nov;69(11):4098-4107
Resolvin E1 and Inhibition of BLT2 Signaling Attenuate the Inflammatory Response and Improve One-Lung Ventilation-Induced Lung Injury.
Ji L, Liu G, Yu G, Xia C, Liu S, Lan Y
Immunological investigations 2024 Nov;53(8):1293-1307
Immunological investigations 2024 Nov;53(8):1293-1307
PM(10) dysregulates epithelial barrier function in human corneal epithelial cells that is restored by antioxidant SKQ1.
Somayajulu M, Wright R, Muhammed F, McClellan SA, Ibrahim A, Hazlett LD
Toxicology and applied pharmacology 2024 Nov;492:117122
Toxicology and applied pharmacology 2024 Nov;492:117122
Ferulic Acid Inhibits Arsenic-Induced Colon Injury by Improving Intestinal Barrier Function.
Wang S, Hong Y, Li Y, Zhang Z, Han J, Yang Z, Yang Y, Ma Z, Wang Q
Environmental toxicology 2024 Nov;39(11):4821-4831
Environmental toxicology 2024 Nov;39(11):4821-4831
Exosomal miR-129-2-3p promotes airway epithelial barrier disruption in PM(2.5)-aggravated asthma.
Wang C, Niu Z, Zhang Y, Liu N, Ji X, Tian J, Guan L, Shi D, Zheng H, Gao Y, Zhao L, Zhang W, Zhang Z
Journal of environmental management 2024 Nov;370:123053
Journal of environmental management 2024 Nov;370:123053
Prevotella melaninogenica disrupted oral epithelial barrier function via myosin light chain kinase.
Guo Y, Han W, He Y
Oral diseases 2024 Nov;30(8):5102-5112
Oral diseases 2024 Nov;30(8):5102-5112
Mechanism of JNK action in oxidative stress-enhanced gut injury by Clostridium perfringens type A infection.
Lin H, Liu Y, Zhang L, Yang F, Liu Y, Li Y, Liu Y, Qiu Z, Chen H, He D, Zhu Y, Gan L
Veterinary microbiology 2024 Nov;298:110223
Veterinary microbiology 2024 Nov;298:110223
Yam protein ameliorates cyclophosphamide-induced intestinal immunosuppression by regulating gut microbiota and its metabolites.
Lu J, Qin H, Liang L, Fang J, Hao K, Song Y, Sun T, Hui G, Xie Y, Zhao Y
International journal of biological macromolecules 2024 Nov;279(Pt 4):135415
International journal of biological macromolecules 2024 Nov;279(Pt 4):135415
High glucose-induced senescence contributes to tubular epithelial cell damage in diabetic nephropathy.
Xu D, Moru P, Liao K, Song W, Yang P, Zang D, Cai C, Zhou H
Experimental gerontology 2024 Nov;197:112609
Experimental gerontology 2024 Nov;197:112609
Oridonin alleviates cigarette smoke-induced nasal polyp formation by promoting autophagy.
Liu P, Wu X, Lv H, Huang J, Gu T, Liu D, Xu Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117547
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117547
Oxymatrine alleviates NSAID-associated small bowel mucosal injury by regulating MIP-1/CCR1 signalling and gut microbiota.
Chen M, Zhou H, Shen J, Wei M, Chen Z, Chen X, Fan H, Zhang J, Zhu J
Journal of pharmacological sciences 2024 Nov;156(3):149-160
Journal of pharmacological sciences 2024 Nov;156(3):149-160
Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique.
Feng YL, Xu XR, Zhu QM, Chang J, Zhang HL, Wang N, Sun JB, Liu J, Zhang J, Sun CP
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155973
m6A-methylase METTL3 promotes retinal angiogenesis through modulation of metabolic reprogramming in RPE cells.
Zhou Q, Liu X, Lu H, Li N, Meng J, Huang J, Zhang Z, Liu J, Fan W, Li W, Li X, Liu X, Zuo H, Yang P, Hou S
Journal of neuroinflammation 2024 Nov 6;21(1):289
Journal of neuroinflammation 2024 Nov 6;21(1):289
Multi-Omics Reveal the Improvements of Nutrient Digestion, Absorption, and Metabolism and Intestinal Function via GABA Supplementation in Weanling Piglets.
Zeng Y, Hu H, He Y, Deng Z, Guo Y, Zhou X
Animals : an open access journal from MDPI 2024 Nov 6;14(22)
Animals : an open access journal from MDPI 2024 Nov 6;14(22)
Downregulated KLF4, induced by m6A modification, aggravates intestinal barrier dysfunction in inflammatory bowel disease.
Zhu X, Wang J, Zhang H, Yue H, Zhu J, Li J, Wang K, Shen K, Yang K, Leng X, Xi Q, Shi T
Cellular and molecular life sciences : CMLS 2024 Nov 29;81(1):470
Cellular and molecular life sciences : CMLS 2024 Nov 29;81(1):470
Low-Medium Polarity Ginsenosides from Wild Ginseng Improves Immunity by Activating the AhR/MAPK Pathway through Tryptophan Metabolism Driven by Gut Microbiota.
Zhang M, Ma L, Luo J, Ren T, Liu S, Pan L, Bao Y, Li F, Dai Y, Pi Z, Yue H, Zheng F
Journal of agricultural and food chemistry 2024 Nov 27;72(47):26142-26154
Journal of agricultural and food chemistry 2024 Nov 27;72(47):26142-26154
ANGPTL4 promotes choroidal neovascularization and subretinal fibrosis through the endothelial‒mesenchymal transition.
Chen J, Yang Y, Su S, Zhang S, Huang J, Chen H, Yang X, Sang A
International ophthalmology 2024 Nov 26;44(1):441
International ophthalmology 2024 Nov 26;44(1):441
Goat milk derived small extracellular vesicles ameliorate LPS-induced intestinal epithelial barrier dysfunction, oxidative stress, and apoptosis by inhibiting the MAPK signaling pathway.
Gao F, Zhang X, Xu Z, Zhang K, Quan F
Food & function 2024 Nov 25;15(23):11590-11607
Food & function 2024 Nov 25;15(23):11590-11607
Ginsenoside Rg1 Alleviates Blood-Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive Autophagy.
Yang S, Fang Z, Duan H, Dong W, Xiao L
Antioxidants (Basel, Switzerland) 2024 Nov 24;13(12)
Antioxidants (Basel, Switzerland) 2024 Nov 24;13(12)
Increased expression of cathepsin C in airway epithelia exacerbates airway remodeling in asthma.
Yuan L, Qin Q, Yao Y, Chen L, Liu H, Du X, Ji M, Wu X, Wang W, Qin Q, Xiang Y, Qing B, Qu X, Yang M, Qin X, Xia Z, Liu C
JCI insight 2024 Nov 22;9(22)
JCI insight 2024 Nov 22;9(22)
The Hydrophobic Amino Acid-Rich Fish Collagen Peptide Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice via Repairing the Intestinal Barrier, Regulating Intestinal Flora and AA Metabolism.
Yang L, Wang Y, Li X, Chen Y, Liang J, He L, Jiang D, Huang S, Hou S
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25690-25703
Journal of agricultural and food chemistry 2024 Nov 20;72(46):25690-25703
APEX1 in intestinal epithelium triggers neutrophil infiltration and intestinal barrier damage in ulcerative colitis.
Chen Q, Chen T, Xiao H, Wang F, Li C, Hu N, Bao L, Tong X, Feng Y, Xu Y, Li C, Zhu JW, Wang D, Li MX
Free radical biology & medicine 2024 Nov 20;225:359-373
Free radical biology & medicine 2024 Nov 20;225:359-373
The P38MAPK Pathway Mediates the Destruction of the Blood-Brain Barrier in Anti-NMDAR Encephalitis Mice.
Lao D, Gong Z, Li T, Mo X, Huang W
Neurochemical research 2024 Nov 19;50(1):21
Neurochemical research 2024 Nov 19;50(1):21
Naringenin Protected Against Blood Brain Barrier Breakdown after Ischemic Stroke through GSK-3β/ β-Catenin Pathway.
Yang Y, Li L, Yu L, Xia Y, Fang Z, Wang S
Neurochemical research 2024 Nov 18;50(1):17
Neurochemical research 2024 Nov 18;50(1):17
Bile acids supplementation improves colonic mucosal barrier via alteration of bile acids metabolism and gut microbiota composition in goats with subacute ruminal acidosis (SARA).
Hou M, Song P, Chen Y, Yang X, Chen P, Cao A, Ni Y
Ecotoxicology and environmental safety 2024 Nov 15;287:117313
Ecotoxicology and environmental safety 2024 Nov 15;287:117313
UCP2 knockout exacerbates sepsis-induced intestinal injury by promoting NLRP3-mediated pyroptosis.
Huang B, Lin G, Chen F, Yang W, Zhang C, Yao Y, Zeng Q, Yang Y, Huang J
International immunopharmacology 2024 Nov 15;141:112935
International immunopharmacology 2024 Nov 15;141:112935
Multiomics profiling uncovers curdione-induced reproductive toxicity in HTR-8/SVneo cells.
Wu Q, Chen M, Lin Y, Zhang J, Gao X, Wu Y, Wu C, Wen J, Li J, Li C, Bao W, Zhang D, Zheng M, Zhu A
Heliyon 2024 Nov 15;10(21):e38650
Heliyon 2024 Nov 15;10(21):e38650
Inflammation-targeted delivery of Urolithin A mitigates chemical- and immune checkpoint inhibitor-induced colitis.
Ghosh S, Singh R, Goap TJ, Sunnapu O, Vanwinkle ZM, Li H, Nukavarapu SP, Dryden GW, Haribabu B, Vemula PK, Jala VR
Journal of nanobiotechnology 2024 Nov 13;22(1):701
Journal of nanobiotechnology 2024 Nov 13;22(1):701
LSD1 deficiency in breast cancer cells promotes the formation of pre-metastatic niches.
Yao Y, Qian R, Gao H, Dai Y, Shi Y, An P, Xin B, Liu Z, Zhang N, Wan Y, He Y, Hu X
NPJ precision oncology 2024 Nov 12;8(1):260
NPJ precision oncology 2024 Nov 12;8(1):260
Pomegranate Peel Extract Mitigates Diarrhea-Predominant Irritable Bowel Syndromes via MAPK and NF-κB Pathway Modulation in Rats.
Zhang Y, Huang S, Zhang S, Hao Z, Shen J
Nutrients 2024 Nov 11;16(22)
Nutrients 2024 Nov 11;16(22)
Mechanism of cigarette smoke in promoting small airway remodeling in mice via STAT 3 / PINK 1-Parkin / EMT.
Wei Y, Li Q, He K, Liao G, Cheng L, Li M, He Z
Free radical biology & medicine 2024 Nov 1;224:447-456
Free radical biology & medicine 2024 Nov 1;224:447-456
Epithelial Piezo1 deletion ameliorates intestinal barrier damage by regulating ferroptosis in ulcerative colitis.
Zhu J, Wu Y, Zhang L, Bai B, Han W, Wang H, Mei Q
Free radical biology & medicine 2024 Nov 1;224:272-286
Free radical biology & medicine 2024 Nov 1;224:272-286
Epigallocatechin gallate alleviated the in vivo toxicity of ZnO nanoparticles to mouse intestine.
Wang C, Huang C, Cao Y
Journal of applied toxicology : JAT 2024 May;44(5):686-698
Journal of applied toxicology : JAT 2024 May;44(5):686-698
Tongfu Lifei Decoction Attenuated Sepsis-Related Intestinal Mucosal Injury Through Regulating Th17/Treg Balance and Modulating Gut Microbiota.
Chen H, Yu Z, Qi Z, Huang X, Gao J
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2024 May;44(5):208-220
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2024 May;44(5):208-220
Carnosol alleviates sepsis-induced pulmonary endothelial barrier dysfunction by targeting nuclear factor erythroid2-related factor 2/sirtuin-3 signaling pathway to attenuate oxidative damage.
Li X, Wang S, Luo M, Wang M, Wu S, Liu C, Wang F, Li Y
Phytotherapy research : PTR 2024 May;38(5):2182-2197
Phytotherapy research : PTR 2024 May;38(5):2182-2197
Lotus Leaf Extract Alleviates Lipopolysaccharide-Induced Intestinal Injury in Mice by Regulating Oxidative Stress and Inflammation.
Su Y, Huang J, Shi P, Li P, Huang P, Zeng J
Journal of medicinal food 2024 May;27(5):428-436
Journal of medicinal food 2024 May;27(5):428-436
Glucose-modified BSA/procyanidin C1 NPs penetrate the blood-brain barrier and alleviate neuroinflammation in Alzheimer's disease models.
Duan L, Hao Z, Ji R, Li X, Wang H, Su Y, Guan F, Ma S
International journal of biological macromolecules 2024 May;268(Pt 1):131739
International journal of biological macromolecules 2024 May;268(Pt 1):131739
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Xu F, Xin Q, Ren M, Shi P, Wang B
Neurochemistry international 2024 May;175:105702
Neurochemistry international 2024 May;175:105702
Integrating Epigenetics, Proteomics, and Metabolomics to Reveal the Involvement of Wnt/β-Catenin Signaling Pathway in Oridonin-Induced Reproductive Toxicity.
Wu Q, Gao X, Lin Y, Wu C, Zhang J, Chen M, Wen J, Wu Y, Tian K, Bao W, Sun P, Zhu A
Toxics 2024 May 7;12(5)
Toxics 2024 May 7;12(5)
Unveiling the Novel Benefits of Co-Administering Butyrate and Active Vitamin D3 in Mice Subjected to Chemotherapy-Induced Gut-Derived Pseudomonas aeruginosa Sepsis.
Huang FC, Huang SC
Biomedicines 2024 May 7;12(5)
Biomedicines 2024 May 7;12(5)
RNA-sequencing expression profile and functional analysis of retinal pigment epithelium in atrophic age-related macular degeneration.
Xu M, Gao Y, Yin W, Liu Q, Yuan S
Journal of biomedical research 2024 May 29;38(5):500-511
Journal of biomedical research 2024 May 29;38(5):500-511
Beneficial effect of heat-killed Lactiplantibacillus plantarum L-137 on intestinal barrier function of rat small intestinal epithelial cells.
Watanabe M, Nakai H, Ohara T, Kawasaki K, Murosaki S, Hirose Y
Scientific reports 2024 May 29;14(1):12319
Scientific reports 2024 May 29;14(1):12319
Exosomes derived from adipose tissue-derived stem cells alleviated H(2)O(2)-induced oxidative stress and endothelial-to-mesenchymal transition in human umbilical vein endothelial cells by inhibition of the mir-486-3p/Sirt6/Smad signaling pathway.
Li Y, Xiao Y, Shang Y, Xu C, Han C, Hu D, Han J, Wang H
Cell biology and toxicology 2024 May 25;40(1):39
Cell biology and toxicology 2024 May 25;40(1):39
Anchang Yuyang Decoction inhibits experimental colitis-related carcinogenesis by regulating PPAR signaling pathway and affecting metabolic homeostasis of host and microbiota.
Wei X, Liang J, Liu J, Dai Y, Leng X, Cheng Y, Chi L
Journal of ethnopharmacology 2024 May 23;326:117995
Journal of ethnopharmacology 2024 May 23;326:117995
Chaihu Guizhi Ganjiang Decoction attenuates nonalcoholic steatohepatitis by enhancing intestinal barrier integrity and ameliorating PPARα mediated lipotoxicity.
Wu H, Lou T, Pan M, Wei Z, Yang X, Liu L, Feng M, Shi L, Qu B, Cong S, Chen K, Yang H, Liu J, Li Y, Jia Z, Xiao H
Journal of ethnopharmacology 2024 May 23;326:117841
Journal of ethnopharmacology 2024 May 23;326:117841
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Sun Z, Xu Y, Shao B, Dang P, Hu S, Sun H, Chen C, Wang C, Liu J, Liu Y, Hu J
Journal for immunotherapy of cancer 2024 May 23;12(5)
Journal for immunotherapy of cancer 2024 May 23;12(5)
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Du Y, Xu Y, Guo X, Tan C, Zhu X, Liu G, Lyu X, Bei C
BMC cancer 2024 May 22;24(1):624
BMC cancer 2024 May 22;24(1):624
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Guo J, Zhang H, Hu H, Zhao T, Ji H, Ma L, Lu J, Yuan J, Xu B
Gene 2024 May 20;907:148276
Gene 2024 May 20;907:148276
Nicotinamide Supplementation Mitigates Oxidative Injury of Bovine Intestinal Epithelial Cells through Autophagy Modulation.
Guo Y, Feng C, Zhang Y, Hu K, Wang C, Wei X
Animals : an open access journal from MDPI 2024 May 16;14(10)
Animals : an open access journal from MDPI 2024 May 16;14(10)
FGF17 protects cerebral ischemia reperfusion-induced blood-brain barrier disruption via FGF receptor 3-mediated PI3K/AKT signaling pathway.
Huang WT, Chen XJ, Lin YK, Shi JF, Li H, Wu HD, Jiang RL, Chen S, Wang X, Tan XX, Chen KY, Wang P
European journal of pharmacology 2024 May 15;971:176521
European journal of pharmacology 2024 May 15;971:176521
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
Liu S, Hu H, Zhang M, Zhang Y, Geng R, Jin Y, Cao Y, Guo W, Liu J, Fu S
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
The therapeutic effects of traditional Chinese medicine on insulin resistance in obese mice by modulating intestinal functions.
Ma L, Bai Y, Liu J, Gong K, He Q, Zhao J, Suo Y, Wang W, Chen G, Lu Z
Heliyon 2024 May 15;10(9):e30379
Heliyon 2024 May 15;10(9):e30379
Metformin attenuates lung ischemia-reperfusion injury and necroptosis through AMPK pathway in type 2 diabetic recipient rats.
Liu T, Wei H, Zhang L, Ma C, Wei Y, Jiang T, Li W
BMC pulmonary medicine 2024 May 14;24(1):237
BMC pulmonary medicine 2024 May 14;24(1):237
Ribosomal Dysregulation in Metastatic Laryngeal Squamous Cell Carcinoma: Proteomic Insights and CX-5461's Therapeutic Promise.
Gao M, Liu T, Hu K, Chen S, Wang S, Gan D, Li Z, Lin X
Toxics 2024 May 13;12(5)
Toxics 2024 May 13;12(5)
An investigation into the HIF-dependent intestinal barrier protective mechanism of Qingchang Wenzhong decoction in ulcerative colitis management.
Yang MJ, Zhang YN, Qiao Z, Xu RY, Chen SM, Hu P, Yu HL, Pan Y, Cao J
Journal of ethnopharmacology 2024 May 10;325:117807
Journal of ethnopharmacology 2024 May 10;325:117807
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3.
Wei YF, Li X, Zhao MR, Liu S, Min L, Zhu ST, Zhang ST, Xie SA
Cell communication and signaling : CCS 2024 May 10;22(1):263
Cell communication and signaling : CCS 2024 May 10;22(1):263
Minimally invasive vagus nerve stimulation modulates mast cell degranulation via the microbiota-gut-brain axis to ameliorate blood-brain barrier and intestinal barrier damage following ischemic stroke.
Wang Y, Tan Q, Pan M, Yu J, Wu S, Tu W, Li M, Jiang S
International immunopharmacology 2024 May 10;132:112030
International immunopharmacology 2024 May 10;132:112030
Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice.
Su Q, Su C, Zhang Y, Guo Y, Liu Y, Liu Y, Yong VW, Xue M
International immunopharmacology 2024 May 10;132:111962
International immunopharmacology 2024 May 10;132:111962
Ginsenoside CK Alleviates DSS-Induced IBD in Mice by Regulating Tryptophan Metabolism and Activating Aryl Hydrocarbon Receptor via Gut Microbiota Modulation.
Liu Y, Bai X, Wu H, Duan Z, Zhu C, Fu R, Fan D
Journal of agricultural and food chemistry 2024 May 1;72(17):9867-9879
Journal of agricultural and food chemistry 2024 May 1;72(17):9867-9879
Cuproptosis mediates copper-induced testicular spermatogenic cell death.
Zhang JY, Yu XJ, Li JJ, Xiao Y, Li GS, Yang F, Dong L
Asian journal of andrology 2024 May 1;26(3):295-301
Asian journal of andrology 2024 May 1;26(3):295-301
Narirutin Attenuates Cerebral Ischemia-Reperfusion Injury by Suppressing the TXNIP/NLRP3 Pathway.
Luo L, Wang S, Liu W, Zhang Z, Zhao M, Liu A
Neurochemical research 2024 Mar;49(3):692-705
Neurochemical research 2024 Mar;49(3):692-705
Inhibition of EphA4 reduces vasogenic edema after experimental stroke in mice by protecting the blood-brain barrier integrity.
Zhang S, Zhao J, Sha WM, Zhang XP, Mai JY, Bartlett PF, Hou ST
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Mar;44(3):419-433
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Mar;44(3):419-433
Age-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.
Wang X, Luo Y, He S, Lu Y, Gong Y, Gao L, Mao S, Liu X, Jiang N, Pu Q, Du D, Shu Y, Hai S, Li S, Chen HN, Zhao Y, Xie D, Qi S, Lei P, Hu H, Xu H, Zhou ZG, Dong B, Zhang H, Zhang Y, Dai L
Nature aging 2024 Mar;4(3):414-433
Nature aging 2024 Mar;4(3):414-433
Cornuside protects against ischemic stroke in rats by suppressing the IL-17F/TRAF6/NF-κB pathway via the brain-gut axis.
Yan C, Liu Z, Xie W, Zhang T, Zhang J, Li G, Xu X, Ye L, Gong J
Experimental neurology 2024 Mar;373:114672
Experimental neurology 2024 Mar;373:114672
Engineered mesenchymal stem cell-derived small extracellular vesicles for diabetic retinopathy therapy through HIF-1α/EZH2/PGC-1α pathway.
Sun F, Sun Y, Wang X, Zhu J, Chen S, Yu Y, Zhu M, Xu W, Qian H
Bioactive materials 2024 Mar;33:444-459
Bioactive materials 2024 Mar;33:444-459
Selective HDAC6 inhibition protects against blood-brain barrier dysfunction after intracerebral hemorrhage.
Peng C, Wang Y, Hu Z, Chen C
CNS neuroscience & therapeutics 2024 Mar;30(3):e14429
CNS neuroscience & therapeutics 2024 Mar;30(3):e14429
Amelioration of obesity and inflammation by polysaccharide from unripe fruits of raspberry via gut microbiota regulation.
Huang Y, Hu J, Xia Q, Tang M, Wang Y, Wang G, Shao X, Yuan H, Li S, Huang P, Peng C, Guo J, Gui S
International journal of biological macromolecules 2024 Mar;261(Pt 2):129825
International journal of biological macromolecules 2024 Mar;261(Pt 2):129825
Ageratina adenophora causes intestinal integrity damage in goats via the activation of the MLCK/ROCK signaling pathway.
Wang J, Wang S, Okyere SK, Wen J, Wang X, Huang R, Tang Z, Cao S, Deng J, Ren Z, Hu Y
Toxicon : official journal of the International Society on Toxinology 2024 Mar;240:107633
Toxicon : official journal of the International Society on Toxinology 2024 Mar;240:107633
Golden bifid treatment regulates gut microbiota and serum metabolites to improve myocardial dysfunction in cecal ligation and puncture-induced sepsis mice.
Wu R, Xu J, Zeng H, Fan Y, Li H, Peng T, Xiao F
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167049
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167049
Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora.
Yang P, Huang S, Luo Z, Zhou S, Zhang C, Zhu Y, Yang J, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116267
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116267
Zinc lactate alleviates oxidative stress by modulating crosstalk between constitutive androstane receptor signaling pathway and gut microbiota profile in weaned piglets.
Tang W, Xiang X, Wang H, Zhou W, He L, Yin Y, Li T
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:23-33
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:23-33
AhR Activation Ameliorates Intestinal Barrier Damage in Immunostressed Piglets by Regulating Intestinal Flora and Its Metabolism.
Wu X, Zhang Y, Ji M, Yang W, Deng T, Hou G, Shi L, Xun W
Animals : an open access journal from MDPI 2024 Mar 4;14(5)
Animals : an open access journal from MDPI 2024 Mar 4;14(5)
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Fan W, Chen H, Li M, Fan X, Jiang F, Xu C, Wang Y, Wei W, Song J, Zhong D, Li G
Scientific reports 2024 Mar 4;14(1):5300
Scientific reports 2024 Mar 4;14(1):5300
Environmentally realistic dose of tire-derived metabolite 6PPD-Q exposure causes intestinal jejunum and ileum damage in mice via cannabinoid receptor-activated inflammation.
Yang Y, Sun N, Lv J, Chen H, Wang H, Xu J, Hu J, Tao L, Fang M, Huang Y
The Science of the total environment 2024 Mar 25;918:170679
The Science of the total environment 2024 Mar 25;918:170679
RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells.
Yang T, Xiang CG, Wang XH, Li QQ, Lei SY, Zhang KR, Ren J, Lu HM, Feng CL, Tang W
Cell death discovery 2024 Mar 23;10(1):152
Cell death discovery 2024 Mar 23;10(1):152
Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model.
Fu Y, Chen YS, Xia DY, Luo XD, Luo HT, Pan J, Ma WQ, Li JZ, Mo QY, Tu Q, Li MM, Zhao Y, Li Y, Huang YT, Chen ZX, Li ZJ, Bernard L, Dione M, Zhang YM, Miao K, Chen JY, Zhu SS, Ren J, Zhou LJ, Jiang XZ, Chen J, Lin ZP, Chen JP, Ye H, Cao QY, Zhu YW, Yang L, Wang X, Wang WC
NPJ biofilms and microbiomes 2024 Mar 20;10(1):25
NPJ biofilms and microbiomes 2024 Mar 20;10(1):25
Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline-Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora.
Cao Y, Leng C, Lin K, Li Y, Zhou M, Zhou M, Shu X, Liu W
Molecules (Basel, Switzerland) 2024 Mar 16;29(6)
Molecules (Basel, Switzerland) 2024 Mar 16;29(6)
Selenomethionine Alleviates Deoxynivalenol-Induced Oxidative Injury in Porcine Intestinal Epithelial Cells Independent of MAPK Pathway Regulation.
Huang Z, Zhong H, Li T, Wang Z, Chen X, Zou T, You J, Chen J
Antioxidants (Basel, Switzerland) 2024 Mar 16;13(3)
Antioxidants (Basel, Switzerland) 2024 Mar 16;13(3)
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
Wei Q, Chen L, Luo W, Chen C, Shi Y, Xie J, Xie X, Luo HB
European journal of pharmacology 2024 Mar 15;967:176353
European journal of pharmacology 2024 Mar 15;967:176353
Trifluoperazine regulates blood-brain barrier permeability via the MLCK/p-MLC pathway to promote ischemic stroke recovery.
Zhang W, Chen S, Ma B, Ding Y, Liu X, He C, Wang B, Yuan M
iScience 2024 Mar 15;27(3):109156
iScience 2024 Mar 15;27(3):109156
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Teng S, Yang Y, Zhang W, Li X, Li W, Cui Z, Min L, Wu J
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice.
Yuan Y, Deng S, Yang J, Shou Z, Wei C, Zhang L, Zhu F, Gao F, Liu X, Liu Y, Chen Q, Fan H
Aging 2024 Mar 11;16(6):5336-5353
Aging 2024 Mar 11;16(6):5336-5353
Achyranthes bidentata polysaccharide ameliorates type 2 diabetes mellitus by gut microbiota-derived short-chain fatty acids-induced activation of the GLP-1/GLP-1R/cAMP/PKA/CREB/INS pathway.
Xia T, He W, Luo Z, Wang K, Tan X
International journal of biological macromolecules 2024 Jun;270(Pt 2):132256
International journal of biological macromolecules 2024 Jun;270(Pt 2):132256
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner.
Liu D, Hu L, Yang Y, Wang Y, Li Y, Su J, Wang G, Gong S
Immunology letters 2024 Jun;267:106853
Immunology letters 2024 Jun;267:106853
Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 pathway.
Long Y, Ang Y, Chen W, Wang Y, Shi M, Hu F, Zhou Q, Shi Y, Ge B, Peng Y, Yu W, Bao H, Li Q, Duan M, Gao J
Free radical biology & medicine 2024 Jun;218:132-148
Free radical biology & medicine 2024 Jun;218:132-148
Rosa laevigata Polysaccharides Ameliorate Dextran Sulfate Sodium-Induced Ulcerative Colitis of Beagles through Regulating Gut Microbiota.
Peng S, Lu X, Lin F, Mao N, Yu L, Zhu T, He J, Yang Y, Liu Z, Wang D
Chemistry & biodiversity 2024 Jun;21(6):e202302102
Chemistry & biodiversity 2024 Jun;21(6):e202302102
Network analysis of microbiome and metabolome to explore the mechanism of raw rhubarb in the protection against ischemic stroke via microbiota-gut-brain axis.
Xian M, Ma Z, Zhan S, Shen L, Li T, Lin H, Huang M, Cai J, Hu T, Liang J, Liang S, Wang S
Fitoterapia 2024 Jun;175:105969
Fitoterapia 2024 Jun;175:105969
Effects of electrolyte balance on intestinal barrier, amino acid metabolism, and mTORC1 signaling pathway in piglets fed low-protein diets.
Lin Q, Tu X, Li X, Gou F, Ding L, Lu Z, Feng J, Ying Y, Hu C
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Jun;17:408-417
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Jun;17:408-417
Paeoniflorin ameliorates chronic colitis via the DR3 signaling pathway in group 3 innate lymphoid cells.
Huang S, Xie X, Xu B, Pan Z, Liang J, Zhang M, Pan S, Wang X, Zhao M, Wang Q, Chen J, Li Y, Zhou L, Luo X
Journal of pharmaceutical analysis 2024 Jun;14(6):100940
Journal of pharmaceutical analysis 2024 Jun;14(6):100940
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Bai X, Deng J, Duan Z, Fu R, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Prevotella copri transplantation promotes neurorehabilitation in a mouse model of traumatic brain injury.
Gu N, Yan J, Tang W, Zhang Z, Wang L, Li Z, Wang Y, Zhu Y, Tang S, Zhong J, Cheng C, Sun X, Huang Z
Journal of neuroinflammation 2024 Jun 4;21(1):147
Journal of neuroinflammation 2024 Jun 4;21(1):147
Tedizolid phosphate alleviates DSS-induced ulcerative colitis by inhibiting senescence of cell and colon tissue through activating AMPK signaling pathway.
Zhou M, Liu ZL, Liu JY, Wang XB
International immunopharmacology 2024 Jun 30;135:112286
International immunopharmacology 2024 Jun 30;135:112286
Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB and PI3K/Akt/mTOR signalling pathways.
Tian X, Li J, Liu S, Dong Q, Fu Y, Luo R, Sun Y, Guo L, Lu Q, Ye C, Liu J, Fu S, Qiu Y
Heliyon 2024 Jun 30;10(12):e33161
Heliyon 2024 Jun 30;10(12):e33161
Network pharmacology and experimental validation to explore the mechanism of Changji'an formula against irritable bowel syndrome with predominant diarrhea.
Ke W, Wu J, Li H, Huang S, Li H, Wang Y, Wu Y, Yuan J, Zhang S, Tang H, Lei K
Heliyon 2024 Jun 30;10(12):e33102
Heliyon 2024 Jun 30;10(12):e33102
Effect and mechanism of Prunella vulgaris L. extract on alleviating lipopolysaccharide-induced acute mastitis in protecting the blood-milk barrier and reducing inflammation.
Luo H, Li Y, Xie J, Xu C, Zhang Z, Li M, Xia B, Shi Z, Lin L
Journal of ethnopharmacology 2024 Jun 28;328:117998
Journal of ethnopharmacology 2024 Jun 28;328:117998
Neferine inhibits BMECs pyroptosis and maintains blood-brain barrier integrity in ischemic stroke by triggering a cascade reaction of PGC-1α.
Zheng ZJ, Zhu LZ, Qiu H, Zheng WY, You PT, Chen SH, Hu CL, Huang JR, Zhou YJ
Scientific reports 2024 Jun 23;14(1):14438
Scientific reports 2024 Jun 23;14(1):14438
MyD88 Inhibition Attenuates Cerebral Ischemia-reperfusion Injury by Regulating the Inflammatory Response and Reducing Blood-brain Barrier Damage.
Jiang F, Xu C, Fan X, Yang S, Fan W, Li M, Song J, Wei W, Chen H, Zhong D, Li G
Neuroscience 2024 Jun 21;549:121-137
Neuroscience 2024 Jun 21;549:121-137
3D model of mouse embryonic pancreas and endocrine compartment using stem cell-derived mesoderm and pancreatic progenitors.
Edri S, Rosenthal V, Ginsburg O, Newman Frisch A, Pierreux CE, Sharon N, Levenberg S
iScience 2024 Jun 21;27(6):109959
iScience 2024 Jun 21;27(6):109959
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Zhao Q, Zhang Z, Zhou X, Rong X, Liu X, Zhao X, Wang H, Pang J, Li S, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Fucoxanthin alleviates lipopolysaccharide-induced intestinal barrier injury in mice.
Du L, Chen C, Yang YH, Zheng Y, Li H, Wu ZJ, Wu H, Miyashita K, Su GH
Food & function 2024 Jun 17;15(12):6359-6373
Food & function 2024 Jun 17;15(12):6359-6373
Heyingwuzi formulation alleviates diabetic retinopathy by promoting mitophagy via the HIF-1α/BNIP3/NIX axis.
Wu JJ, Zhang SY, Mu L, Dong ZG, Zhang YJ
World journal of diabetes 2024 Jun 15;15(6):1317-1339
World journal of diabetes 2024 Jun 15;15(6):1317-1339
Elucidating the modulatory role of dietary hydroxyproline on the integrity and functional performance of the intestinal barrier in early-weaned piglets: A comprehensive analysis of its interplay with the gut microbiota and metabolites.
Tang Z, Yang Y, Yang M, Jiang D, Ge Y, Zhang X, Liu H, Fu Q, Liu X, Yang Y, Wu Z, Ji Y
International immunopharmacology 2024 Jun 15;134:112268
International immunopharmacology 2024 Jun 15;134:112268
ACE2 mediates tryptophan alleviation on diarrhea by repairing intestine barrier involved mTOR pathway.
Li J, Yan Y, Fu Y, Chen Z, Yang Y, Li Y, Pan J, Li F, Zha C, Miao K, Ben L, Saleemi MK, Zhu Y, Ye H, Yang L, Wang W
Cellular & molecular biology letters 2024 Jun 14;29(1):90
Cellular & molecular biology letters 2024 Jun 14;29(1):90
Butyrate attenuates sympathetic activation in rats with chronic heart failure by inhibiting microglial inflammation in the paraventricular nucleus.
Liu C, Yu H, Xia H, Wang Z, Li B, Xue H, Jin S, Xiao L, Wu Y, Guo Q
Acta biochimica et biophysica Sinica 2024 Jun 11;56(12):1823-1832
Acta biochimica et biophysica Sinica 2024 Jun 11;56(12):1823-1832
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy.
Cao C, Zhang H, He Z, Zhang K, Qian Z, Shen J, Zheng L, Xue M, Sun S, Li C, Zhao W, Jing J, Ma R, Ge X, Yao B
Lipids in health and disease 2024 Jun 11;23(1):180
Lipids in health and disease 2024 Jun 11;23(1):180
Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier.
Xu T, Yang J, Xu Y, Wang X, Gao X, Sun J, Zhou C, Huang Y
Neural regeneration research 2024 Jun 1;19(6):1344-1350
Neural regeneration research 2024 Jun 1;19(6):1344-1350
Anthrahydroquinone‑2,6‑disulfonate attenuates PQ‑induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of the PI3K/AKT/eNOS pathway.
Li N, Yi Y, Chen J, Huang Y, Peng J, Li Z, Wang Y, Zhang J, Xu C, Liu H, Li J, Liu X
International journal of molecular medicine 2024 Jul;54(1)
International journal of molecular medicine 2024 Jul;54(1)
Mucoadhesive chitosan-catechol as an efficient vaccine delivery system for intranasal immunization.
Deng K, Huang Z, Jing B, Zhu L, Feng Y, Jiang Q, Xu Z, Wan H, Zhao X
International journal of biological macromolecules 2024 Jul;273(Pt 1):133008
International journal of biological macromolecules 2024 Jul;273(Pt 1):133008
Development of an Inflamed High Throughput Stem-cell-based Gut Epithelium Model to Assess the Impact of Annexin A1.
Broering MF, Tocci S, Sout NT, Reutelingsperger C, Farsky SHP, Das S, Sayed IM
Stem cell reviews and reports 2024 Jul;20(5):1299-1310
Stem cell reviews and reports 2024 Jul;20(5):1299-1310
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Lu J, Liu G, Sun W, Jia G, Zhao H, Chen X, Wang J
The Journal of nutrition 2024 Jul;154(7):2087-2096
The Journal of nutrition 2024 Jul;154(7):2087-2096
Dietary emulsifier polysorbate 80 exposure accelerates age-related cognitive decline.
Zhang L, Yin Z, Liu X, Jin G, Wang Y, He L, Li M, Pang X, Yan B, Jia Z, Ma J, Wei J, Cheng F, Li D, Wang L, Han Z, Liu Q, Chen F, Cao H, Lei P
Brain, behavior, and immunity 2024 Jul;119:171-187
Brain, behavior, and immunity 2024 Jul;119:171-187
Inhibition of Experimental Corneal Neovascularization by the Tight Junction Protein ZO-1.
Yao Q, Wu H, Ren H, Cao J, Shao Y, Liu G, Lu P
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2024 Jul-Aug;40(6):379-388
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2024 Jul-Aug;40(6):379-388
Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression.
Liang Z, Ge Y, Li J, Bai Y, Xiao Z, Yan R, An G, Zhang D
Journal of cancer research and clinical oncology 2024 Jul 9;150(7):342
Journal of cancer research and clinical oncology 2024 Jul 9;150(7):342
Dietary Protease Supplementation Improved Growth Performance and Nutrients Digestion via Modulating Intestine Barrier, Immunological Response, and Microbiota Composition in Weaned Piglets.
Liu T, Ma W, Wang J, Wei Y, Wang Y, Luo Z, Zhang Y, Zeng X, Guan W, Shao D, Chen F
Antioxidants (Basel, Switzerland) 2024 Jul 8;13(7)
Antioxidants (Basel, Switzerland) 2024 Jul 8;13(7)
New advances of NG2-expressing cell subset in marrow mesenchymal stem cells as novel therapeutic tools for liver fibrosis/cirrhosis.
Hu D, Lai J, Chen Q, Bai L
Stem cell research & therapy 2024 Jul 6;15(1):199
Stem cell research & therapy 2024 Jul 6;15(1):199
Sestrin2 Restricts Endothelial-to-Mesenchymal Transition Induced by Lipolysaccharide via Autophagy.
Huang R, Liu L, Shen K, Duan C, Fan Z
Journal of integrative neuroscience 2024 Jul 5;23(7):124
Journal of integrative neuroscience 2024 Jul 5;23(7):124
The Use of Polysaccharide AOP30 from the Rhizome of Alpinia officinarum Hance to Alleviate Lipopolysaccharide-Induced Intestinal Epithelial Barrier Dysfunction and Inflammation via the TLR4/NfκB Signaling Pathway in Caco-2 Cell Monolayers.
Jia X, Huang Y, Liu G, Li Z, Tan Q, Zhong S
Nutrients 2024 Jul 5;16(13)
Nutrients 2024 Jul 5;16(13)
Platelet-rich plasma-derived exosomes promote blood-spinal cord barrier repair and attenuate neuroinflammation after spinal cord injury.
Nie X, Liu Y, Yuan T, Yu T, Yun Z, Xue W, Yu T, An J, Dai A, Wu K, Liu Q
Journal of nanobiotechnology 2024 Jul 31;22(1):456
Journal of nanobiotechnology 2024 Jul 31;22(1):456
The Barrier Disruption and Pyroptosis of Intestinal Epithelial Cells Caused by Perfringolysin O (PFO) from Clostridium perfringens.
Liu Z, Mou S, Li L, Chen Q, Yang R, Guo S, Jin Y, Liu L, Li T, Chen H, Wang X
Cells 2024 Jul 3;13(13)
Cells 2024 Jul 3;13(13)
Study on the mechanism of mitigating radiation damage by improving the hematopoietic system and intestinal barrier with Tenebrio molitor peptides.
Shang Y, Cui P, Chen Y, Zhang Z, Li S, Chen Z, Ma A, Jia Y
Food & function 2024 Jul 29;15(15):8116-8127
Food & function 2024 Jul 29;15(15):8116-8127
Protection of Tight Junctional Complexes between hCMEC/D3 Cells by Deep-Sea Fibrinolytic Compound FGFC1.
Diao X, Han H, Sun H, Zhang H, Wu W
Marine drugs 2024 Jul 26;22(8)
Marine drugs 2024 Jul 26;22(8)
Arbutin alleviates intestinal colitis by regulating neutrophil extracellular traps formation and microbiota composition.
Qin D, Liu J, Guo W, Ju T, Fu S, Liu D, Hu G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155741
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155741
Narirutin mitigates dextrose sodium sulfate-induced colitis in mice by modulating intestinal flora.
Xu D, Liu D, Jiang N, Xie Y, He D, Cheng J, Liu J, Fu S, Hu G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155730
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155730
High correlated color temperature artificial lighting impairs retinal pigment epithelium integrity and chloride ion transport: A potential mechanism for choroidal thinning.
Zhang C, Jiao Q, Wang M, Zhu Z, Zhao J, Zheng Y
Biochemical and biophysical research communications 2024 Jul 23;718:150078
Biochemical and biophysical research communications 2024 Jul 23;718:150078
Protective effects of patchouli alcohol against DSS-induced ulcerative colitis.
Han H, Gao M, Wang F, Luo Z, Jiang X, Qiu Y, Su J, Duan X, Luo S, Tang S, Khan A, Zou Z, Chen C, Yin Q, Qiu J, Zhang H
Scientific reports 2024 Jul 20;14(1):16745
Scientific reports 2024 Jul 20;14(1):16745
Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells.
Lin Z, Schaefer K, Lui I, Yao Z, Fossati A, Swaney DL, Palar A, Sali A, Wells JA
Science (New York, N.Y.) 2024 Jul 19;385(6706):eadl5763
Science (New York, N.Y.) 2024 Jul 19;385(6706):eadl5763
Neuroprotection of macamide in a mouse model of Alzheimer's disease involves Nrf2 signaling pathway and gut microbiota.
Xia N, Xu L, Huang M, Xu D, Li Y, Wu H, Mei Z, Yu Z
European journal of pharmacology 2024 Jul 15;975:176638
European journal of pharmacology 2024 Jul 15;975:176638
Nerve growth factor alleviates arsenic-induced testicular injury by enhancing the function of Sertoli cells.
Yang Y, Hong Y, Han J, Yang Z, Huang N, Xu B, Ma Z, Wang Q
Ecotoxicology and environmental safety 2024 Jul 15;280:116578
Ecotoxicology and environmental safety 2024 Jul 15;280:116578
Epigallocatechin-3-gallate mitigates cadmium-induced intestinal damage through modulation of the microbiota-tryptophan-aryl hydrocarbon receptor pathway.
Li M, Yan Q, Chen C, Hu T, Yin H, Zhao L, Shi F, Ye G, Yin L, Liang X, Li Y, Tang H
Ecotoxicology and environmental safety 2024 Jul 15;280:116520
Ecotoxicology and environmental safety 2024 Jul 15;280:116520
Apple polysaccharide improves age-matched cognitive impairment and intestinal aging through microbiota-gut-brain axis.
Zhang W, Zhong Y, Wang Z, Tang F, Zheng C
Scientific reports 2024 Jul 13;14(1):16215
Scientific reports 2024 Jul 13;14(1):16215
Maternal exposure to DON during lactation induces testicular toxicity in pubertal and adult offspring mice.
Sun P, Liu M, Zhou S, Yang L, Xie S, Riaz H, Huo L, Liang A
Ecotoxicology and environmental safety 2024 Jul 1;279:116468
Ecotoxicology and environmental safety 2024 Jul 1;279:116468
pH Sensitive Quercetin Nanoparticles Ameliorate DSS-Induced Colitis in Mice by Colon-Specific Delivery.
Wang L, Fu R, Meng Y, Liang J, Xue W, Hu H, Meng J, Zhang M
Molecular nutrition & food research 2024 Jan;68(2):e2300051
Molecular nutrition & food research 2024 Jan;68(2):e2300051
Addition of α-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems.
Yang ZX, Zhang Y, Wang Q, Zhang L, Liu YF, Zhang Y, Ren Y, Zhou C, Gao HW, Zhang NX, Feng LY
Acta pharmacologica Sinica 2024 Jan;45(1):36-51
Acta pharmacologica Sinica 2024 Jan;45(1):36-51
Quercetin ameliorates ulcerative colitis by activating aryl hydrocarbon receptor to improve intestinal barrier integrity.
Wang X, Xie X, Li Y, Xie X, Huang S, Pan S, Zou Y, Pan Z, Wang Q, Chen J, Zhou L, Luo X
Phytotherapy research : PTR 2024 Jan;38(1):253-264
Phytotherapy research : PTR 2024 Jan;38(1):253-264
Simultaneous ischemic regions targeting and BBB crossing strategy to harness extracellular vesicles for therapeutic delivery in ischemic stroke.
Liang HB, Chen X, Zhao R, Li SJ, Huang PS, Tang YH, Cui GH, Liu JR
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1037-1057
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1037-1057
Angiotensin-converting enzyme inhibitory peptide IVGFPAYGH protects against liver injury in mice fed a high‑sodium diet by inhibiting the RAS and remodeling gut microbial communities.
Zou L, Yu X, Cai K, Xu B, Chen C, Xiao G
International journal of biological macromolecules 2024 Jan;256(Pt 1):128265
International journal of biological macromolecules 2024 Jan;256(Pt 1):128265
Chitosan-coated artesunate protects against ulcerative colitis via STAT6-mediated macrophage M2 polarization and intestinal barrier protection.
Tao Y, Xu L, Liu X, Wang P, Wei S, Huang Y, Gu W, Bo R, Liu M, Yu J, Li J
International journal of biological macromolecules 2024 Jan;254(Pt 1):127680
International journal of biological macromolecules 2024 Jan;254(Pt 1):127680
PSD-95 inhibitor Tat-NR2B9c (NA-1) protects the integrity of the blood-brain barrier after transient middle artery occlusion in rats by downregulating matrix metalloprotease-9 and upregulating endothelial nitric oxide synthase.
Xu Y, Xu L, Xu C, Zhao M, Xu T, Xia L, Wu Y, Cao Y, Han Z
Brain research bulletin 2024 Jan;206:110836
Brain research bulletin 2024 Jan;206:110836
An Erythrocyte Membrane-Derived Nanosystem for Efficient Reversal of Endothelial Injury in Sepsis.
Zhang Y, Li J, Jing Q, Chen Z, Wang K, Sun C
Advanced healthcare materials 2024 Jan;13(3):e2302320
Advanced healthcare materials 2024 Jan;13(3):e2302320
The protective effects of icariin against testicular dysfunction in type 1 diabetic mice Via AMPK-mediated Nrf2 activation and NF-κB p65 inhibition.
Lu CS, Wu CY, Wang YH, Hu QQ, Sun RY, Pan MJ, Lu XY, Zhu T, Luo S, Yang HJ, Wang D, Wang HW
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155217
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155217
Cantharidin-induced toxic injury, oxidative stress, and autophagy attenuated by Astragalus polysaccharides in mouse testis.
Xiao Y, Liu R, Tang W, Yang C
Reproductive toxicology (Elmsford, N.Y.) 2024 Jan;123:108520
Reproductive toxicology (Elmsford, N.Y.) 2024 Jan;123:108520
Probiotic Clostridium butyricum ameliorates cognitive impairment in obesity via the microbiota-gut-brain axis.
Zheng M, Ye H, Yang X, Shen L, Dang X, Liu X, Gong Y, Wu Q, Wang L, Ge X, Fang X, Hou B, Zhang P, Tang R, Zheng K, Huang XF, Yu Y
Brain, behavior, and immunity 2024 Jan;115:565-587
Brain, behavior, and immunity 2024 Jan;115:565-587
Trimethylamine-N oxide enhances post-stroke depression progression via ROS-p38/MAPK signaling.
Hu Y, Liu Y, Wang H, Wang X
Human & experimental toxicology 2024 Jan-Dec;43:9603271241306396
Human & experimental toxicology 2024 Jan-Dec;43:9603271241306396
Infant feces-derived Lactobacillus gasseri FWJL-4 mitigates experimental necrotizing enterocolitis via acetate production.
Pan LL, Sun Y, Dong X, Ren Z, Li B, Yang P, Zhang L, Sun J
Gut microbes 2024 Jan-Dec;16(1):2430541
Gut microbes 2024 Jan-Dec;16(1):2430541
Gut microbiota promotes macrophage M1 polarization in hepatic sinusoidal obstruction syndrome via regulating intestinal barrier function mediated by butyrate.
Zhao S, Zhang H, Zhu H, Zhao T, Tu J, Yin X, Yang S, Zhang W, Zhang F, Zhang M, Xu B, Zhuge Y, Xiao J
Gut microbes 2024 Jan-Dec;16(1):2377567
Gut microbes 2024 Jan-Dec;16(1):2377567
Prevotella copri promotes vascular calcification via lipopolysaccharide through activation of NF-κB signaling pathway.
Hao QY, Yan J, Wei JT, Zeng YH, Feng LY, Que DD, Li SC, Guo JB, Fan Y, Ding YF, Zhang XL, Yang PZ, Gao JW, Li ZH
Gut microbes 2024 Jan-Dec;16(1):2351532
Gut microbes 2024 Jan-Dec;16(1):2351532
Meta-analysis identifying gut microbial biomarkers of Qinghai-Tibet Plateau populations and the functionality of microbiota-derived butyrate in high-altitude adaptation.
Zhao H, Sun L, Liu J, Shi B, Zhang Y, Qu-Zong CR, Dorji T, Wang T, Yuan H, Yang J
Gut microbes 2024 Jan-Dec;16(1):2350151
Gut microbes 2024 Jan-Dec;16(1):2350151
Renal macrophages monitor and remove particles from urine to prevent tubule obstruction.
He J, Cao Y, Zhu Q, Wang X, Cheng G, Wang Q, He R, Lu H, Weng Y, Mao G, Bao Y, Wang J, Liu X, Han F, Shi P, Shen XZ
Immunity 2024 Jan 9;57(1):106-123.e7
Immunity 2024 Jan 9;57(1):106-123.e7
Study on the Anti-Ulcerative Colitis Effect of Pseudo-Ginsenoside RT4 Based on Gut Microbiota, Pharmacokinetics, and Tissue Distribution.
Yu H, Wang C, Wu J, Wang Q, Liu H, Li Z, He S, Wang C, Liu J
International journal of molecular sciences 2024 Jan 9;25(2)
International journal of molecular sciences 2024 Jan 9;25(2)
Macrophage-derived MMP12 promotes fibrosis through sustained damage to endothelial cells.
Zhou X, Zhang C, Yang S, Yang L, Luo W, Zhang W, Zhang X, Chao J
Journal of hazardous materials 2024 Jan 5;461:132733
Journal of hazardous materials 2024 Jan 5;461:132733
Inhibition of circulating exosomes release with GW4869 mitigates severe acute pancreatitis-stimulated intestinal barrier damage through suppressing NLRP3 inflammasome-mediated pyroptosis.
Shao Y, Jiang Y, Wang J, Li H, Li C, Zhang D
International immunopharmacology 2024 Jan 5;126:111301
International immunopharmacology 2024 Jan 5;126:111301
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
Wang G, Li Z, Lin P, Zhang H, Wang Y, Zhang T, Wang H, Li H, Lin L, Zhao Y, Jia L, Chen Y, Ji H, Zhao W, Fu Z, Zhong Z
International immunopharmacology 2024 Jan 5;126:111183
International immunopharmacology 2024 Jan 5;126:111183
FTO-mediated m6A modification of serum amyloid A2 mRNA promotes podocyte injury and inflammation by activating the NF-κB signaling pathway.
Lang Y, Wang Q, Sheng Q, Lu S, Yang M, Kong Z, Gao Y, Fan X, Shen N, Wang R, Lv Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23409
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23409
The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway.
Zhou L, Yang Y, Fu X, Xia B, Li C, Lu C, Qi Y, Zhang H, Liu T
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117100
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117100
Standalone cell culture microfluidic device-based microphysiological system for automated cell observation and application in nephrotoxicity tests.
Kimura H, Nakamura H, Goto T, Uchida W, Uozumi T, Nishizawa D, Shinha K, Sakagami J, Doi K
Lab on a chip 2024 Jan 30;24(3):408-421
Lab on a chip 2024 Jan 30;24(3):408-421
Targeted mRNA Nanoparticles Ameliorate Blood-Brain Barrier Disruption Postischemic Stroke by Modulating Microglia Polarization.
Gao M, Li Y, Ho W, Chen C, Chen Q, Li F, Tang M, Fan Q, Wan J, Yu W, Xu X, Li P, Zhang XQ
ACS nano 2024 Jan 30;18(4):3260-3275
ACS nano 2024 Jan 30;18(4):3260-3275
Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.
Wang Y, Xie Z, Wu X, Du L, Chong Z, Liu R, Han J
Foods (Basel, Switzerland) 2024 Jan 3;13(1)
Foods (Basel, Switzerland) 2024 Jan 3;13(1)
Ageratina adenophora damages the rumen epithelium via inducing the expression of inflammatory factors in goats.
Wang X, Wang J, Okyere SK, Huang R, Shao C, Yousif M, Deng J, Hu Y
Journal of animal science 2024 Jan 3;102
Journal of animal science 2024 Jan 3;102
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
Cui L, Zou S, Liu J, Lv H, Li H, Zhang Z
International immunopharmacology 2024 Jan 25;127:111404
International immunopharmacology 2024 Jan 25;127:111404
Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium.
Angyal D, Groeneweg TA, Leung A, Desain M, Dulla K, de Jonge HR, Bijvelds MJC
Cellular & molecular biology letters 2024 Jan 23;29(1):18
Cellular & molecular biology letters 2024 Jan 23;29(1):18
Dietary supplementation of benzoic acid and essential oils combination enhances intestinal resilience against LPS stimulation in weaned piglets.
Cui C, Wei Y, Wang Y, Ma W, Zheng X, Wang J, Ma Z, Wu C, Chu L, Zhang S, Guan W, Chen F
Journal of animal science and biotechnology 2024 Jan 19;15(1):4
Journal of animal science and biotechnology 2024 Jan 19;15(1):4
A Platform for Testing the Biocompatibility of Implants: Silicone Induces a Proinflammatory Response in a 3D Skin Equivalent.
Nuwayhid R, Schulz T, Siemers F, Schreiter J, Kobbe P, Hofmann G, Langer S, Kurow O
Biomedicines 2024 Jan 19;12(1)
Biomedicines 2024 Jan 19;12(1)
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.
Yang R, Wang X, Liu H, Chen J, Tan C, Chen H, Wang X
Cell communication and signaling : CCS 2024 Jan 17;22(1):44
Cell communication and signaling : CCS 2024 Jan 17;22(1):44
Dietary long-chain fatty acids promote colitis by regulating palmitoylation of STAT3 through CD36-mediated endocytosis.
Wei Y, Li J, Li J, Liu C, Guo X, Liu Z, Zhang L, Bao S, Wu X, Su W, Wang X, Zhang J, Dong W
Cell death & disease 2024 Jan 17;15(1):60
Cell death & disease 2024 Jan 17;15(1):60
Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox.
Wang W, Yang T, Chen S, Liang L, Wang Y, Ding Y, Xiong W, Ye X, Guo Y, Shen S, Chen H, Chen J
Journal of biological engineering 2024 Jan 16;18(1):7
Journal of biological engineering 2024 Jan 16;18(1):7
Levofloxacin alleviates blood-brain barrier disruption following cerebral ischemia and reperfusion via directly inhibiting A-FABP.
Yang S, Xu D, Zhang D, Huang X, Li S, Wang Y, Lu J, Wang D, Guo ZN, Yang Y, Ye D, Wang Y, Xu A, Hoo RLC, Chang J
European journal of pharmacology 2024 Jan 15;963:176275
European journal of pharmacology 2024 Jan 15;963:176275
Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway.
Wu S, Du W, Wu Z, Wen F, Zhong X, Huang X, Gu H, Wang J
Ecotoxicology and environmental safety 2024 Jan 15;270:115887
Ecotoxicology and environmental safety 2024 Jan 15;270:115887
Baitouweng decoction repairs the intestinal barrier in DSS-induced colitis mice via regulation of AMPK/mTOR-mediated autophagy.
Pan SM, Wang CL, Hu ZF, Zhang ML, Pan ZF, Zhou RY, Wang XJ, Huang SW, Li YY, Wang Q, Luo X, Zhou L, Hou JT, Chen B
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116888
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116888
Torreya grandis Kernel Oil Alleviates Loperamide-Induced Slow Transit Constipation via Up-Regulating the Colonic Expressions of Occludin/Claudin-1/ZO-1 and 5-HT3R/5-HT4R in BALB/c Mice.
Wang X, Guo R, Yu Z, Zikela L, Li J, Li S, Han Q
Molecular nutrition & food research 2024 Feb;68(4):e2300615
Molecular nutrition & food research 2024 Feb;68(4):e2300615
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Lu T, Ding L, Zheng X, Li Y, Wei W, Liu W, Tao J, Xue X
Molecular neurobiology 2024 Feb;61(2):753-771
Molecular neurobiology 2024 Feb;61(2):753-771
Gut microbiota dysbiosis and intestinal barrier impairment in diarrhea caused by cold drink and high-fat diet.
Tian Y, Fu M, Su J, Yan M, Yu J, Wang C, Niu Z, Du Y, Hu X, Zheng J, Tao B, Gao Z, Chen J, Chen S, Lv G
Toxicology 2024 Feb;502:153728
Toxicology 2024 Feb;502:153728
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Li Z, Wang B, Tian L, Zheng B, Zhao X, Liu R
Inflammation 2024 Feb;47(1):376-389
Inflammation 2024 Feb;47(1):376-389
Assessment of osteopontin as an early nephrotoxicity indicator in human renal proximal tubule cells and its application in evaluating lanthanum-induced nephrotoxicity.
Chen Y, Xu F, Xiao X, Chi H, Lai Y, Lin X, Li Q, Song J, Wu W, Li Z, Yang X
Ecotoxicology and environmental safety 2024 Feb;271:115928
Ecotoxicology and environmental safety 2024 Feb;271:115928
Bone morphogenetic protein 4 thermosensitive hydrogel inhibits corneal neovascularization by repairing corneal epithelial apical junctional complexes.
Nan W, Shen S, Yang Y, Wu M, He Y, Zhang R, Cui X, Zhang Y
Materials today. Bio 2024 Feb;24:100944
Materials today. Bio 2024 Feb;24:100944
peu-MIR2916-p3-enriched garlic exosomes ameliorate murine colitis by reshaping gut microbiota, especially by boosting the anti-colitic Bacteroides thetaiotaomicron.
Wang X, Liu Y, Dong X, Duan T, Wang C, Wang L, Yang X, Tian H, Li T
Pharmacological research 2024 Feb;200:107071
Pharmacological research 2024 Feb;200:107071
Fluorene-9-bisphenol exposure damages the testis in mice through a novel mechanism of ferroptosis.
Feng Q, Liu Y, Zou L, Lei M, Zhu C, Xia W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Feb;184:114385
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Feb;184:114385
Fermentation enhances the amelioration effect of bee pollen on Caco-2 monolayer epithelial barrier dysfunction based on NF-κB-mediated MLCK-MLC signaling pathway.
Zhang H, Liu M, Song F, Zhu X, Lu Q, Liu R
Food research international (Ottawa, Ont.) 2024 Feb;178:113938
Food research international (Ottawa, Ont.) 2024 Feb;178:113938
Sinomenine regulates the cholinergic anti-inflammatory pathway to inhibit TLR4/NF-κB pathway and protect the homeostasis in brain and gut in scopolamine-induced Alzheimer's disease mice.
Ni H, Liu M, Cao M, Zhang L, Zhao Y, Yi L, Li Y, Liu L, Wang P, Du Q, Zhou H, Dong Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116190
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Feb;171:116190
Electroacupuncture at ST36 modulates the intestinal microecology and may help repair the intestinal barrier in the rat model of severe acute pancreatitis.
Xu H, Wen Q, Hu H, Yang S, Lu L, Hu X, Li H, Huang X, Li N
Microbial biotechnology 2024 Feb;17(2):e14401
Microbial biotechnology 2024 Feb;17(2):e14401
Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata (Desv.) Spring against inflammatory bowel disease.
Hui H, Wang Z, Zhao X, Xu L, Yin L, Wang F, Qu L, Peng J
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
Journal of pharmaceutical analysis 2024 Feb;14(2):177-195
(-)-Syringaresinol attenuates ulcerative colitis by improving intestinal epithelial barrier function and inhibiting inflammatory responses.
Liu Y, Wu J, Tan L, Li Z, Gao P, He S, Wang Q, Tang D, Wang C, Wang F, Li P, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155292
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155292
CpxAR two-component system contributes to virulence properties of Cronobacter sakazakii.
Jin T, Zhan X, Pang L, Peng B, Zhang X, Zhu W, Yang B, Xia X
Food microbiology 2024 Feb;117:104393
Food microbiology 2024 Feb;117:104393
Microsporidia persistence in host impairs epithelial barriers and increases chances of inflammatory bowel disease.
Jin J, Tang Y, Cao L, Wang X, Chen Y, An G, Zhang H, Pan G, Bao J, Zhou Z
Microbiology spectrum 2024 Feb 6;12(2):e0361023
Microbiology spectrum 2024 Feb 6;12(2):e0361023
The Effects of Yeast Protein on Gut Microbiota in Mice When Compared with Soybean Protein and Whey Protein Isolates.
Zhou X, Liang L, Sun B, Li K, Guo H, Zhang Y
Nutrients 2024 Feb 5;16(3)
Nutrients 2024 Feb 5;16(3)
Neuron Derived Cold-Inducible RNA-Binding Protein Promotes NETs Formation to Exacerbate Brain Endothelial Barrier Disruption after Ischemic Stroke.
Li Z, Sun S, Xiao Q, Tan S, Jin H, Hu B
Aging and disease 2024 Feb 4;16(1):520-539
Aging and disease 2024 Feb 4;16(1):520-539
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice.
Yang YH, Chen C, Zheng Y, Wu ZJ, Zhou MQ, Liu XY, Miyashita K, Duan DL, Du L
Journal of agricultural and food chemistry 2024 Feb 28;72(8):4142-4154
Journal of agricultural and food chemistry 2024 Feb 28;72(8):4142-4154
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.
Jia L, Liu X, Liu X, Guan Q, Tian Y, Li J, Zhao P
Chinese medicine 2024 Feb 28;19(1):32
Chinese medicine 2024 Feb 28;19(1):32
Cathepsin B-Responsive Programmed Brain Targeted Delivery System for Chemo-Immunotherapy Combination Therapy of Glioblastoma.
Jiang S, Li W, Yang J, Zhang T, Zhang Y, Xu L, Hu B, Li Z, Gao H, Huang Y, Ruan S
ACS nano 2024 Feb 27;18(8):6445-6462
ACS nano 2024 Feb 27;18(8):6445-6462
An Inulin-Type Fructan CP-A from Codonopsis pilosula Alleviated 5-Fluorouracil-Induced Intestinal Mucositis via the ERK/MLCK/MLC2 Pathway and Regulation of Gut Microbiota.
Zhou J, Li D, Wang J, Cheng Z, Wang C, Zhang X, Xu X, Gao J
Pharmaceuticals (Basel, Switzerland) 2024 Feb 26;17(3)
Pharmaceuticals (Basel, Switzerland) 2024 Feb 26;17(3)
Intrauterine Growth Restriction Affects Colonic Barrier Function via Regulating the Nrf2/Keap1 and TLR4-NF-κB/ERK Pathways and Altering Colonic Microbiome and Metabolome Homeostasis in Growing-Finishing Pigs.
Xiong L, Azad MAK, Liu Y, Zhang W, Zhu Q, Hu C, You J, Kong X
Antioxidants (Basel, Switzerland) 2024 Feb 26;13(3)
Antioxidants (Basel, Switzerland) 2024 Feb 26;13(3)
The microbial metabolite urolithin A reduces Clostridioides difficile toxin expression and toxin-induced epithelial damage.
Ghosh S, Erickson D, Chua MJ, Collins J, Jala VR
mSystems 2024 Feb 20;9(2):e0125523
mSystems 2024 Feb 20;9(2):e0125523
A Mixture of Formic Acid, Benzoic Acid, and Essential Oils Enhanced Growth Performance via Modulating Nutrient Uptake, Mitochondrion Metabolism, and Immunomodulation in Weaned Piglets.
Wang X, Deng T, Zhou X, Chu L, Zeng X, Zhang S, Guan W, Chen F
Antioxidants (Basel, Switzerland) 2024 Feb 19;13(2)
Antioxidants (Basel, Switzerland) 2024 Feb 19;13(2)
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
Yu S, Wang X, Li Z, Jin D, Yu M, Li J, Li Y, Liu X, Zhang Q, Liu Y, Liu R, Wang X, Fang B, Zhang C, Wang R, Ren F
Journal of translational medicine 2024 Feb 17;22(1):169
Journal of translational medicine 2024 Feb 17;22(1):169
A single cell atlas of circulating immune cells involved in diabetic retinopathy.
Liao D, Fan W, Li N, Li R, Wang X, Liu J, Wang H, Hou S
iScience 2024 Feb 16;27(2):109003
iScience 2024 Feb 16;27(2):109003
Disrupting the gut microbiota/metabolites axis by Di-(2-ethylhexyl) phthalate drives intestinal inflammation via AhR/NF-κB pathway in mice.
Cheng X, Chen J, Guo X, Cao H, Zhang C, Hu G, Zhuang Y
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123232
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123232
Isofraxidin attenuates dextran sulfate sodium-induced ulcerative colitis through inhibiting pyroptosis by upregulating Nrf2 and reducing reactive oxidative species.
He S, Zhang T, Wang YY, Yuan W, Li L, Li J, Yang YY, Wu DM, Xu Y
International immunopharmacology 2024 Feb 15;128:111570
International immunopharmacology 2024 Feb 15;128:111570
Melatonin alleviates necrotizing enterocolitis by reducing bile acid levels through the SIRT1/FXR signalling axis.
Lai J, Li F, Li H, Huang R, Ma F, Gu X, Cai Y, Huang D, Li S, Xiao S, Hao H
International immunopharmacology 2024 Feb 15;128:111360
International immunopharmacology 2024 Feb 15;128:111360
Irisin links Claudin-5 preservation and Mfn2-mediated mitochondrial dynamics to resist doxorubicin-induced cardiac endothelial damage.
He J, Hou L, Liu Q, Zhou R
Biochemical and biophysical research communications 2024 Feb 12;696:149501
Biochemical and biophysical research communications 2024 Feb 12;696:149501
Icariin Regulates EMT and Stem Cell-Like Character in Breast Cancer through Modulating lncRNA NEAT1/TGFβ/SMAD2 Signaling Pathway.
Song B, Wei F, Peng J, Wei X, Liu M, Nie Z, Ma Y, Peng T
Biological & pharmaceutical bulletin 2024 Feb 10;47(2):399-410
Biological & pharmaceutical bulletin 2024 Feb 10;47(2):399-410
DPP-4 exacerbates LPS-induced endothelial cells inflammation via integrin-α5β1/FAK/AKT signaling.
Liu C, Xu J, Fan J, Liu C, Xie W, Kong H
Experimental cell research 2024 Feb 1;435(1):113909
Experimental cell research 2024 Feb 1;435(1):113909
A multi-omics analysis of viral nucleic acid poly(I:C) responses to mammalian testicular stimulation.
Yang D, Wu W, Lu Q, Mou Y, Chen W, Wan S, Zhang M, Wang C, Du X, Li N, Hua J
Stress biology 2024 Feb 1;4(1):9
Stress biology 2024 Feb 1;4(1):9
Inulin alleviates perfluorooctanoic acid-induced intestinal injury in mice by modulating the PI3K/AKT/mTOR signaling pathway.
Zhang QY, Zhong MT, Gi M, Chen YK, Lai MQ, Liu JY, Liu YM, Wang Q, Xie XL
Environmental pollution (Barking, Essex : 1987) 2024 Feb 1;342:123090
Environmental pollution (Barking, Essex : 1987) 2024 Feb 1;342:123090
Therapeutic potential of Lacticaseibacillus rhamnosus grx10 and its derived postbiotic through gut microbiota and MAPK/MLCK/MLC pathway-mediated intestinal barrier repairment in ulcerative colitis.
Ye H, Liu X, Guan K, Ma Y, Liu R, Liu Y, Lv X, Wang R, Li Q
Journal of food science 2024 Dec;89(12):10035-10052
Journal of food science 2024 Dec;89(12):10035-10052
SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP.
Rehmani T, Dias AP, Applin BD, Salih M, Tuana BS
Life science alliance 2024 Dec;7(12)
Life science alliance 2024 Dec;7(12)
An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Xu L, Ge S
Molecular neurobiology 2024 Dec;61(12):10097-10114
Molecular neurobiology 2024 Dec;61(12):10097-10114
Effects of Intestinal M Cells on Intestinal Barrier and Neuropathological Properties in an AD Mouse Model.
Wu S, Hu L, Fu Y, Chen Y, Hu Z, Li H, Liu Z
Molecular neurobiology 2024 Dec;61(12):10006-10022
Molecular neurobiology 2024 Dec;61(12):10006-10022
Nicotinamide mononucleotide protects STAT1 from oxidative stress-induced degradation to prevent colorectal tumorigenesis.
Li T, Luo C, Liu Z, Li J, Han M, Zhang R, Chen Y, Deng H
MedComm 2024 Dec;5(12):e70006
MedComm 2024 Dec;5(12):e70006
Tea-derived exosome-like nanoparticles prevent irritable bowel syndrome induced by water avoidance stress in rat model.
Gong Q, Xiong F, Zheng Y, Guo Y
Journal of gastroenterology and hepatology 2024 Dec;39(12):2690-2699
Journal of gastroenterology and hepatology 2024 Dec;39(12):2690-2699
Targeted reprogramming of tumor-associated macrophages for overcoming glioblastoma resistance to chemotherapy and immunotherapy.
Li J, Yang J, Jiang S, Tian Y, Zhang Y, Xu L, Hu B, Shi H, Li Z, Ran G, Huang Y, Ruan S
Biomaterials 2024 Dec;311:122708
Biomaterials 2024 Dec;311:122708
Methane saline suppresses ferroptosis via the Nrf2/HO-1 signaling pathway to ameliorate intestinal ischemia-reperfusion injury.
Fan Q, Chang H, Tian L, Zheng B, Liu R, Li Z
Redox report : communications in free radical research 2024 Dec;29(1):2373657
Redox report : communications in free radical research 2024 Dec;29(1):2373657
Rehmannia glutinosa polysaccharides enhance intestinal immunity of mice through regulating the microbiota.
Yu L, Lin F, Yu Y, Deng X, Shi X, Lu X, Lu Y, Wang D
International journal of biological macromolecules 2024 Dec;283(Pt 3):137878
International journal of biological macromolecules 2024 Dec;283(Pt 3):137878
Schisandra chinensis polysaccharide prevents alcohol-associated liver disease in mice by modulating the gut microbiota-tryptophan metabolism-AHR pathway axis.
Chi YY, Xiang JY, Li HM, Shi HY, Ning K, Shi C, Xiang H, Xie Q
International journal of biological macromolecules 2024 Dec;282(Pt 2):136843
International journal of biological macromolecules 2024 Dec;282(Pt 2):136843
RVG-peptide-camouflaged iron-coordinated engineered polydopamine nanoenzyme with ROS scavenging and inhibiting inflammatory response for ischemic stroke therapy.
Liu H, Zhuo R, Zou C, Xu S, Cai X, Ge Y, Liu G, Wu C, Dai C, Li J, Fan Z, Yang L, Li Y
International journal of biological macromolecules 2024 Dec;282(Pt 1):136778
International journal of biological macromolecules 2024 Dec;282(Pt 1):136778
Tanshinone IIA Exerts Cardioprotective Effects Through Improving Gut-Brain Axis Post-Myocardial Infarction.
Zhu T, Chen J, Zhang M, Tang Z, Tong J, Hao X, Li H, Xu J, Yang J
Cardiovascular toxicology 2024 Dec;24(12):1317-1334
Cardiovascular toxicology 2024 Dec;24(12):1317-1334
Growth hormone attenuates obesity and reshapes gut microbiota in high-fat diet-fed mice.
Wang Y, Ran L, Zhang F, Li H, Cha Q, Yang K, Wang H, Wu Y, Yu Z
Metabolism open 2024 Dec;24:100326
Metabolism open 2024 Dec;24:100326
SOX9 regulates epithelial-mesenchymal transformation by mediating the Wnt/β-catenin signaling pathway in hypospadias.
He X, Zhang Z, Liu Z, Zhang Q, Long C, Shen L, Wei G, Liu X
Pediatric discovery 2024 Dec;2(4):e94
Pediatric discovery 2024 Dec;2(4):e94
Lactobacillus reuteri or Lactobacillus rhamnosus GG intervention facilitates gut barrier function, decreases corticosterone and ameliorates social behavior in LPS-exposed offspring.
Wang X, Hu R, Lin F, Yang T, Lu Y, Sun Z, Li T, Chen J
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115212
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115212
Intestinal barrier, immunity and gut microbiota-based protective effects of Lactococcus lactis HF08 and its postbiotic derivative on aging and aging colitis mice.
Liu X, Ma Y, Guan K, Liu R, Mao K, Xu X, Li Q, Wang R
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115164
Food research international (Ottawa, Ont.) 2024 Dec;197(Pt 1):115164
Dietary sanguinarine supplementation improves the growth performance and intestinal immunity of broilers.
Su Y, Chang G, Liu J, Huang P, Zeng J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Dec;19:76-89
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Dec;19:76-89
Hymenolepis nana antigens alleviate ulcerative colitis by promoting intestinal stem cell proliferation and differentiation via AhR/IL-22 signaling pathway.
Cui X, Cheng Y, Wang H, Li X, Li J, Zhang K, Mou R
PLoS neglected tropical diseases 2024 Dec;18(12):e0012714
PLoS neglected tropical diseases 2024 Dec;18(12):e0012714
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Li X, Li J, Ji J, Li S, Yao X, Fan H, Yao R
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Counteracting Alzheimer's disease via normalizing neurovascular unit with a self-regulated multi-functional nano-modulator.
Xia X, Wei Y, Huang Q, Zhou Y, Wang X, Shi Y, Yang X, Yang W, Zhang Y, Lei T, Huang Y, Li H, Qin M, Gao H
Acta pharmaceutica Sinica. B 2024 Dec;14(12):5464-5478
Acta pharmaceutica Sinica. B 2024 Dec;14(12):5464-5478
Licorice-regulated gut-joint axis for alleviating collagen-induced rheumatoid arthritis.
Yang D, Lv G, Wu Y, Guo W, Wang Y, Hu J, Li N, Zheng F, Dai Y, Pi Z, Yue H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156203
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156203
Ganjiang Huangqin Huanglian Renshen Decoction protects against ulcerative colitis by modulating inflammation, oxidative stress, and gut microbiota.
Zhou C, Peng B, Zhang M, Yang Y, Yi Z, Wu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156172
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156172
Chidan Tuihuang granule modulates gut microbiota to influence NOD1/RIPK2 pathway in cholestatic liver injury recovery.
Chen Y, Hu Q, Zhang W, Gong Q, Yan J, Wang Z, Zhou Z, Ma X, Li Y, Lu X, Efferth T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156164
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156164
Jianwei Shoutai Pills alleviates miscarriage by modulating gut microbial production of BAs and NLRP3-inflammasome at the maternal-fetal interface of rats.
Chen S, Xue X, Zhang H, Huang X, Lin X, He J, Chen L, Luo S, Gao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156000
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156000
Xuanfei Baidu decoction ameliorates bleomycin-elicited idiopathic pulmonary fibrosis in mice by regulating the lung-gut crosstalk via IFNγ/STAT1/STAT3 axis.
Jia M, Liu Y, Liu J, Meng J, Cao J, Miao L, Zhang H, Zhu Y, Sun M, Yang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155997
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155997
Resistant starch confers protection of dietary against diabetic cardiomyopathy.
Zhu Q, Lu X, Zhang T, Shi M, Gao R, Zhou Y, Zhang H, Yao W, Qi C, Liao S, Li X
The Journal of nutritional biochemistry 2024 Dec;134:109766
The Journal of nutritional biochemistry 2024 Dec;134:109766
Lipopolysaccharide-regulated RNF31/NRF2 axis in colonic epithelial cells mediates homeostasis of the intestinal barrier in ulcerative colitis.
Tang CT, Liu ZD, Wang P, Zeng CY, Chen YX
Cellular signalling 2024 Dec;124:111480
Cellular signalling 2024 Dec;124:111480
Identification of Ferroptosis-Related Gene in Age-Related Macular Degeneration Using Machine Learning.
Zhu M, Yu J
Immunity, inflammation and disease 2024 Dec;12(12):e70059
Immunity, inflammation and disease 2024 Dec;12(12):e70059
ReBiA-Robotic Enabled Biological Automation: 3D Epithelial Tissue Production.
Königer L, Malkmus C, Mahdy D, Däullary T, Götz S, Schwarz T, Gensler M, Pallmann N, Cheufou D, Rosenwald A, Möllmann M, Groneberg D, Popp C, Groeber-Becker F, Steinke M, Hansmann J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(45):e2406608
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(45):e2406608
Quercetin prevents the USP22-Snail1 signaling pathway to ameliorate diabetic tubulointerstitial fibrosis.
Zhao X, Wang S, He X, Wei W, Huang K
Food & function 2024 Dec 9;15(24):11990-12006
Food & function 2024 Dec 9;15(24):11990-12006
Xiaoyaosan against depression through suppressing LPS mediated TLR4/NLRP3 signaling pathway in "microbiota-gut-brain" axis.
Liu X, Liu H, Wu X, Zhao Z, Wang S, Wang H, Qin X
Journal of ethnopharmacology 2024 Dec 5;335:118683
Journal of ethnopharmacology 2024 Dec 5;335:118683
Isoastragaloside I attenuates cholestatic liver diseases by ameliorating liver injury, regulating bile acid metabolism and restoring intestinal barrier.
Zhang L, Jiang X, Shi J, Zhang J, Shi X, Xie Z, Chen G, Zhang H, Mu Y, Chen J, Qi S, Liu P, Liu W
Journal of ethnopharmacology 2024 Dec 5;335:118649
Journal of ethnopharmacology 2024 Dec 5;335:118649
Therapeutic Efficacy and Underlying Mechanisms of a Mannoglucan from Hirsutella sinensis Mycelium on Dextran Sulfate Sodium-Induced Inflammatory Bowel Disease in Mice: Modulation of the Intestinal Barrier, Oxidative Stress and Gut Microbiota.
Ni W, Li Y, Feng J, Liu B, Yuan H, Tai G, Bi H
International journal of molecular sciences 2024 Dec 5;25(23)
International journal of molecular sciences 2024 Dec 5;25(23)
High-fat diet led to testicular inflammation and ferroptosis via dysbiosis of gut microbes.
Zhang Z, Chen H, Li Q
International immunopharmacology 2024 Dec 5;142(Pt B):113235
International immunopharmacology 2024 Dec 5;142(Pt B):113235
Formononetin ameliorates dextran sulfate sodium-induced colitis via enhancing antioxidant capacity, promoting tight junction protein expression and reshaping M1/M2 macrophage polarization balance.
Xiao Q, Huang J, Zhu X, Shi M, Chen L, Chen L, Liu X, Liu R, Zhong Y
International immunopharmacology 2024 Dec 5;142(Pt B):113174
International immunopharmacology 2024 Dec 5;142(Pt B):113174
Efficacy of DHA-enriched phosphatidylserine and its underlying mechanism in alleviating polystyrene nanoplastics-induced hepatotoxicity in mice.
Zhang Y, Zhao Q, Zhao R, Lu Y, Jiang S, Tang Y
International immunopharmacology 2024 Dec 5;142(Pt A):113154
International immunopharmacology 2024 Dec 5;142(Pt A):113154
FGF20 modulates gut microbiota to mitigate dextran sodium sulfate-induced ulcerative colitis in mouse models.
Jin Z, Liu Z, Pan J, Wang S, Cui M, He C, Lin M, Liu X, Yu X, Gong F
International immunopharmacology 2024 Dec 5;142(Pt A):113044
International immunopharmacology 2024 Dec 5;142(Pt A):113044
Salidroside alleviates ferroptosis in FAC-induced Age-related macular degeneration models by activating Nrf2/SLC7A11/GPX4 axis.
Zhu M, Yu J
International immunopharmacology 2024 Dec 5;142(Pt A):113041
International immunopharmacology 2024 Dec 5;142(Pt A):113041
Bone morphogenetic protein 4 inhibits corneal neovascularization by blocking NETs-induced disruption to corneal epithelial barrier.
Shen S, Nan W, Zhang W, Wu H, Zhang Y
International immunopharmacology 2024 Dec 5;142(Pt A):113023
International immunopharmacology 2024 Dec 5;142(Pt A):113023
Intranasal administration of Clostridium butyricum and its derived extracellular vesicles alleviate LPS-induced acute lung injury.
Liu L, Zheng C, Xu Z, Wang Z, Zhong Y, He Z, Zhang W, Zhang Y
Microbiology spectrum 2024 Dec 5;12(12):e0210824
Microbiology spectrum 2024 Dec 5;12(12):e0210824
The host cells suppress the proliferation of pseudorabies virus by regulating the PI3K/Akt/mTOR pathway.
Xu L, Tao Q, Zhang Y, Lee F-q, Xu T, Deng L-s, Jian Z-j, Zhao J, Lai S-y, Zhou Y-c, Zhu L, Xu Z-w
Microbiology spectrum 2024 Dec 5;12(12):e0135124
Microbiology spectrum 2024 Dec 5;12(12):e0135124
Rewiring Tryptophan Metabolism via Programmable Probiotic Integrated by Dual-Layered Microcapsule Protects against Inflammatory Bowel Disease in Mice.
Li W, Liu Y, Zheng X, Han J, Shi A, Wong CC, Wang R, Jing X, Li Y, Fan S, Zhang C, Chen Y, Guo G, Yu J, She J
ACS nano 2024 Dec 31;18(52):35443-35464
ACS nano 2024 Dec 31;18(52):35443-35464
CD8+T cell infiltration-associated barrier function of brain endothelial cells is enhanced by astragalus polysaccharides via inhibiting the PI3K/AKT signaling pathway.
Zhao Y, Lu Q, Ma J, Ding G, Wang X, Qiao X, Wang Y, Cheng X
Journal of leukocyte biology 2024 Dec 31;117(1)
Journal of leukocyte biology 2024 Dec 31;117(1)
Gut-Microbiota-Derived Butyric Acid Overload Contributes to Ileal Mucosal Barrier Damage in Late Phase of Chronic Unpredictable Mild Stress Mice.
Wang C, Qiu M, Wang S, Luo J, Huang L, Deng Q, Fang Z, Sun L, Gooneratne R
International journal of molecular sciences 2024 Dec 3;25(23)
International journal of molecular sciences 2024 Dec 3;25(23)
Spint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA.
Lin HH, Yu IS, Cheng MS, Chang TJ, Lin HY, Chang YC, Ko CJ, Chen PH, Lin SW, Huang TC, Huang SY, Chen TY, Kan KW, Huang HP, Lee MS
Nature communications 2024 Dec 3;15(1):10537
Nature communications 2024 Dec 3;15(1):10537
N7-methyladenosine-induced SLC7A7 serves as a prognostic biomarker in pan-cancer and promotes CRC progression in colorectal cancer.
Wang F, Zhang S, Chen Z, Gu X, Zhang G, Zhang H, Yuan W
Scientific reports 2024 Dec 28;14(1):30755
Scientific reports 2024 Dec 28;14(1):30755
Snake venom weakens neurovascular integrity and promotes vulnerability to neuroinflammation.
Feng Z, Fang C, Yu M, Wang Y, Abiola OF, Lin J, Liu Y, Zeng Z, Zeng L, Mo Z, Ma Y
International immunopharmacology 2024 Dec 25;143(Pt 3):113586
International immunopharmacology 2024 Dec 25;143(Pt 3):113586
Nicotinamide adenine dinucleotide phosphate alleviates intestinal ischemia/reperfusion injury via Nrf2/HO-1 pathway.
Chen SY, Xu H, Qin Y, He TQ, Shi RR, Xing YR, Xu J, Cong RC, Wang MR, Yang JS, Gu JH, He BS
International immunopharmacology 2024 Dec 25;143(Pt 2):113478
International immunopharmacology 2024 Dec 25;143(Pt 2):113478
Neutrophil extracellular traps induce barrier dysfunction in DSS-induced ulcerative colitis via the cGAS-STING pathway.
Sun T, Wang P, Zhai X, Wang Z, Miao X, Yang Y, Wu J
International immunopharmacology 2024 Dec 25;143(Pt 1):113358
International immunopharmacology 2024 Dec 25;143(Pt 1):113358
Sphk1/S1P pathway promotes blood-brain barrier breakdown after intracerebral hemorrhage through inducing Nlrp3-mediated endothelial cell pyroptosis.
Feng M, An Y, Qin Q, Fong IH, Zhang K, Wang F, Song D, Li M, Yu M, Yeh CT, Chang J, Guo F
Cell death & disease 2024 Dec 23;15(12):926
Cell death & disease 2024 Dec 23;15(12):926
Salivary adenoid cystic carcinoma-derived α2,6-sialylated extracellular vesicles increase vascular permeability by triggering ER-stress in endothelial cells and promote lung metastasis.
Dong Q, Dong M, Liu X, Zhou J, Wu S, Liu Z, Niu W, Liu T
Cancer letters 2024 Dec 20;611:217407
Cancer letters 2024 Dec 20;611:217407
Role of Rab13, Protein Kinase A, and Zonula Occludens-1 in Hepatitis E Virus Entry and Cell-to-Cell Spread: Comparative Analysis of Quasi-Enveloped and Non-Enveloped Forms.
Nagashima S, Primadharsini PP, Takahashi M, Nishiyama T, Murata K, Okamoto H
Pathogens (Basel, Switzerland) 2024 Dec 20;13(12)
Pathogens (Basel, Switzerland) 2024 Dec 20;13(12)
Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability.
Yang Q, Wan Q, Wang Z
Scientific reports 2024 Dec 2;14(1):29848
Scientific reports 2024 Dec 2;14(1):29848
Fructo-oligosaccharides Alleviated Ulcerative Colitis via Gut Microbiota-Dependent Tryptophan Metabolism in Association with Aromatic Hydrocarbon Receptor Activation in Mice.
Yang C, Du Y, Li Q, Liu L, Zhao L, Gao C, Tang Z, Zhang X, Zhao Y, Yang X
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27912-27922
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27912-27922
Inhibition of AhR disrupts intestinal epithelial barrier and induces intestinal injury by activating NF-κB in COPD.
Tao L, Zhang Q, Liu L, Wang K, Wang J, Liu X, Zhao P, Li J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70256
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70256
2-(3,4-Dihydroxyphenyl)ethyl 3-hydroxybutanoate Ameliorates Cognitive Dysfunction and Inflammation Via Modulating Gut Microbiota in Aged Senescence-Accelerated Mouse Prone8 Mice.
Shi L, Gao P, Zhang Y, Liu Q, Hu R, Zhao Z, Hu Y, Xu X, Shen Y, Liu J, Long J
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Dec 1;79(12)
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Dec 1;79(12)
Inulin alleviates GenX-induced intestinal injury in mice by modulating the MAPK pathway, cell cycle, and cell adhesion proteins.
Zhang QY, Lai MQ, Chen YK, Zhong MT, Gi M, Wang Q, Xie XL
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124974
Environmental pollution (Barking, Essex : 1987) 2024 Dec 1;362:124974
Omega-3 Polyunsaturated Fatty Acids Alleviate Intestinal Barrier Dysfunction in Obstructive Jaundice Rats.
Zhang C, Yin Z, Hu F, Lin X, Guan Q, Zhang F, Zhang X
Molecular biotechnology 2024 Aug;66(8):1954-1960
Molecular biotechnology 2024 Aug;66(8):1954-1960
Raddeanin A Protects the BRB Through Inhibiting Inflammation and Apoptosis in the Retina of Alzheimer's Disease.
Wang XF, Xiang XH, Wei J, Zhang PB, Xu Q, Liu MH, Qu LQ, Wang XX, Yu L, Wu AG, Qing DL, Wu JM, Law BY, Yu CL, Yong-Tang
Neurochemical research 2024 Aug;49(8):2197-2214
Neurochemical research 2024 Aug;49(8):2197-2214
HSP70 protects against acute pancreatitis-elicited intestinal barrier damage in rats.
Chen S, Qin R, Zhang Z, Fan X, Zhou L, Wang H
Clinics and research in hepatology and gastroenterology 2024 Aug;48(7):102388
Clinics and research in hepatology and gastroenterology 2024 Aug;48(7):102388
Fecal Microbiota Transplantation Alleviates Allergic Rhinitis via CD4(+) T Cell Modulation Through Gut Microbiota Restoration.
Dong L, Tang Y, Wen S, He Y, Li F, Deng Y, Tao Z
Inflammation 2024 Aug;47(4):1278-1297
Inflammation 2024 Aug;47(4):1278-1297
Auraptene Mitigates Colitis Induced by Dextran Sulfate Sodium in Mice by Regulating Specific Intestinal Flora and Repairing the Intestinal Barrier.
Chen T, Jin N, Zhang Q, Li Z, Wang Q, Fang X
Inflammation 2024 Aug;47(4):1127-1141
Inflammation 2024 Aug;47(4):1127-1141
Long noncoding RNA H19 knockdown promotes angiogenesis via IMP2 after ischemic stroke.
Zhong L, Fan J, Yan F, Yang Z, Hu Y, Li L, Wang R, Zheng Y, Luo Y, Liu P
CNS neuroscience & therapeutics 2024 Aug;30(8):e70000
CNS neuroscience & therapeutics 2024 Aug;30(8):e70000
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
Xue W, Tianrun W, Jiaqi Y, Xin L, Ruxue D, Peng Z
Ecotoxicology and environmental safety 2024 Aug;281:116636
Ecotoxicology and environmental safety 2024 Aug;281:116636
A2 reactive astrocyte-derived exosomes alleviate cerebral ischemia-reperfusion injury by delivering miR-628.
Wang Y, Li H, Sun H, Xu C, Sun H, Wei W, Song J, Jia F, Zhong D, Li G
Journal of cellular and molecular medicine 2024 Aug;28(16):e70004
Journal of cellular and molecular medicine 2024 Aug;28(16):e70004
Chitosan-alginate/R8 ternary polyelectrolyte complex as an oral protein-based vaccine candidate induce effective mucosal immune responses.
Liu Y, Long M, Wang Y, Liang Z, Dong Y, Qu M, Ge X, Nan Y, Chen Y, Zhou X
International journal of biological macromolecules 2024 Aug;275(Pt 2):133671
International journal of biological macromolecules 2024 Aug;275(Pt 2):133671
Nur77 as a novel regulator of Paneth cell differentiation and function.
Cui C, Wang X, Zheng Y, Wu L, Li L, Wei H, Peng J
Mucosal immunology 2024 Aug;17(4):752-767
Mucosal immunology 2024 Aug;17(4):752-767
Dissection of triple-negative breast cancer microenvironment and identification of potential therapeutic drugs using single-cell RNA sequencing analysis.
Cheng W, Mi W, Wang S, Wang X, Jiang H, Chen J, Yang K, Jiang W, Ye J, Guo B, Zhang Y
Journal of pharmaceutical analysis 2024 Aug;14(8):100975
Journal of pharmaceutical analysis 2024 Aug;14(8):100975
Expression of MAF bZIP transcription factor B protects against ulcerative colitis through the inhibition of the NF-κB pathway.
Li J, Li Q, Ma W, Zhang Y, Li X
Immunity, inflammation and disease 2024 Aug;12(8):e1372
Immunity, inflammation and disease 2024 Aug;12(8):e1372
A Glucose-Responsive Hydrogel Inhibits Primary and Secondary BRB Injury for Retinal Microenvironment Remodeling in Diabetic Retinopathy.
Zhou Y, Zhao C, Shi Z, Heger Z, Jing H, Shi Z, Dou Y, Wang S, Qiu Z, Li N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(32):e2402368
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(32):e2402368
Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.
Zhao W, Shen T, Zhao B, Li M, Deng Z, Huo Y, Aernouts B, Loor JJ, Psifidi A, Xu C
Journal of animal science and biotechnology 2024 Aug 9;15(1):109
Journal of animal science and biotechnology 2024 Aug 9;15(1):109
Schisandrin B alleviates testicular inflammation and Sertoli cell apoptosis via AR-JNK pathway.
Zhang BY, Yang R, Zhu WQ, Zhu CL, Chen LX, Zhao YS, Zhang Y, Wang YQ, Jiang DZ, Tang B, Zhang XM
Scientific reports 2024 Aug 8;14(1):18418
Scientific reports 2024 Aug 8;14(1):18418
Gut-derived memory γδ T17 cells exacerbate sepsis-induced acute lung injury in mice.
Xie B, Wang M, Zhang X, Zhang Y, Qi H, Liu H, Wu Y, Wen X, Chen X, Han M, Xu D, Sun X, Zhang X, Zhao X, Shang Y, Yuan S, Zhang J
Nature communications 2024 Aug 7;15(1):6737
Nature communications 2024 Aug 7;15(1):6737
Colonization of microbiota derived from Macaca fascicularis, Bama miniature pigs, beagle dogs, and C57BL/6J mice alleviates DSS-induced colitis in germ-free mice.
Yang Y, Zhang Z, Wang Y, Rao J, Sun J, Wu Z, He J, Tan X, Liang L, Yu Q, Wu Z, Zou H, Zhang H, Dong M, Zheng J, Feng S, Cheng W, Wei H
Microbiology spectrum 2024 Aug 6;12(8):e0038824
Microbiology spectrum 2024 Aug 6;12(8):e0038824
The Novel-m0230-3p miRNA Modulates the CSF1/CSF1R/Ras Pathway to Regulate the Cell Tight Junctions and Blood-Testis Barrier in Yak.
Yan Q, Wang Q, Zhang Y, Yuan L, Hu J, Zhao X
Cells 2024 Aug 5;13(15)
Cells 2024 Aug 5;13(15)
Ultrasound-responsive theranostic platform for the timely monitoring and efficient thrombolysis in thrombi of tPA resistance.
Lin L, Ba Z, Tian H, Qin H, Chen X, Zhou X, Zhao S, Li L, Xue F, Li H, He L, Li X, Du J, Zhou Z, Zeng W
Nature communications 2024 Aug 4;15(1):6610
Nature communications 2024 Aug 4;15(1):6610
Pasteurella multocida infection induces blood-brain barrier disruption by decreasing tight junctions and adherens junctions between neighbored brain microvascular endothelial cells.
Lin L, Bi H, Yang J, Shang Y, Lv Q, Zhang D, Huang X, Zhao M, Wang F, Hua L, Chen H, Wu B, Wang X, Peng Z
Veterinary research 2024 Aug 29;55(1):104
Veterinary research 2024 Aug 29;55(1):104
Pseudorabies virus infection increases the permeability of the mammalian respiratory barrier to facilitate Pasteurella multocida infection.
Zhang D, Lin L, Yang J, Lv Q, Wang M, Hua L, Zhang K, Chen H, Wu B, Peng Z
mSphere 2024 Aug 28;9(8):e0029724
mSphere 2024 Aug 28;9(8):e0029724
Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy.
Liao M, Zhu X, Lu Y, Yi X, Hu Y, Zhao Y, Ye Z, Guo X, Liang M, Jin X, Zhang H, Wang X, Zhao Z, Chen Y, Yan H
Nature communications 2024 Aug 25;15(1):7324
Nature communications 2024 Aug 25;15(1):7324
Integrated Multi-Omics Analysis Reveals Mountain-Cultivated Ginseng Ameliorates Cold-Stimulated Steroid-Resistant Asthma by Regulating Interactions among Microbiota, Genes, and Metabolites.
Tang D, Wang C, Liu H, Wu J, Tan L, Liu S, Lv H, Wang C, Wang F, Liu J
International journal of molecular sciences 2024 Aug 22;25(16)
International journal of molecular sciences 2024 Aug 22;25(16)
Role of gut microbiota in Crohn's disease pathogenesis: Insights from fecal microbiota transplantation in mouse model.
Wu Q, Yuan LW, Yang LC, Zhang YW, Yao HC, Peng LX, Yao BJ, Jiang ZX
World journal of gastroenterology 2024 Aug 21;30(31):3689-3704
World journal of gastroenterology 2024 Aug 21;30(31):3689-3704
Epimedii Folium decoction ameliorates osteoporosis in mice through NLRP3/caspase-1/IL-1β signalling pathway and gut-bone axis.
Ma F, Zhang W, Zhou G, Qi Y, Mao HR, Chen J, Lu Z, Wu W, Zou X, Deng D, Lv S, Xiang N, Wang X
International immunopharmacology 2024 Aug 20;137:112472
International immunopharmacology 2024 Aug 20;137:112472
GM130-silencing may aggravate blood-brain barrier damage and affect microglia polarization by down-regulating PD-L1 expression after experimental intracerebral hemorrhage.
Chen X, Ren Y, Xie P, Lei Q, Lu W
Molecular biology reports 2024 Aug 19;51(1):919
Molecular biology reports 2024 Aug 19;51(1):919
Oral alginate microspheres for the efficient site-specific delivery of epidermal growth factor attenuated murine ulcerative colitis via repairing the mucosal barrier.
Chen B, Li D, Tong B, Wang L, Lin H, Xu H, Hu S
International journal of pharmaceutics 2024 Aug 15;661:124394
International journal of pharmaceutics 2024 Aug 15;661:124394
Seliciclib alleviates ulcerative colitis by inhibiting ferroptosis and improving intestinal inflammation.
Song Y, Song Q, Tan F, Wang Y, Li C, Liao S, Yu K, Mei Z, Lv L
Life sciences 2024 Aug 15;351:122794
Life sciences 2024 Aug 15;351:122794
Dietary rutin improves the antidiarrheal capacity of weaned piglets by improving intestinal barrier function, antioxidant capacity and cecal microbiota composition.
Ma L, Zhou B, Liu H, Chen S, Zhang J, Wang T, Wang C
Journal of the science of food and agriculture 2024 Aug 15;104(10):6262-6275
Journal of the science of food and agriculture 2024 Aug 15;104(10):6262-6275
Kidney-tonifying blood-activating decoction delays ventricular remodeling in rats with chronic heart failure by regulating gut microbiota and metabolites and p38 mitogen-activated protein kinase/p65 nuclear factor kappa-B/aquaporin-4 signaling pathway.
Xu R, Bi Y, He X, Zhang Y, Zhao X
Journal of ethnopharmacology 2024 Aug 10;330:118110
Journal of ethnopharmacology 2024 Aug 10;330:118110
Pueraria lobata-Prunus mume Complex Alleviates Alcoholic Liver Disease by Regulating Lipid Metabolism and Inhibiting Inflammation: A Transcriptome and Gut Microbiota Analysis.
Gao R, Huang Q, Zeng Y, Chen D, Jia Z, Han B, Huang X, Wang Q, Hu X, Liao M, Li J
Foods (Basel, Switzerland) 2024 Aug 1;13(15)
Foods (Basel, Switzerland) 2024 Aug 1;13(15)
l-Theanine Prevents Colonic Damage via NF-κB/MAPK Signaling Pathways Induced by a High-Fat Diet in Rats.
Fang C, Shen Y, Ma Z, Li Y, Zhang J, Liu C, Ye Y
Molecular nutrition & food research 2024 Apr;68(8):e2300797
Molecular nutrition & food research 2024 Apr;68(8):e2300797
Naringenin Alleviates Radiation-Induced Intestinal Injury by Inhibiting TRPV6 in Mice.
Ling Z, Wang Z, Chen L, Mao J, Ma D, Han X, Tian L, Zhu Q, Lu G, Yan X, Ding Y, Xiao W, Chen Y, Peng A, Yin X
Molecular nutrition & food research 2024 Apr;68(8):e2300745
Molecular nutrition & food research 2024 Apr;68(8):e2300745
Protective Mechanism of Polysaccharide ORP-1 Isolated from Oudemansiella raphanipes against Age-Related Cognitive Decline through the Microbiota-Gut-Brain Axis.
Ren YR, Cui WT, Jiang KL, He KQ, Lu YM, Chen Y, Pan WJ
Molecular nutrition & food research 2024 Apr;68(7):e2300739
Molecular nutrition & food research 2024 Apr;68(7):e2300739
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Zeng J, Lu QQ, Du XL, Yuan L, Yang XJ
Journal of molecular histology 2024 Apr;55(2):201-210
Journal of molecular histology 2024 Apr;55(2):201-210
Protective effect of cilostazol on vascular injury in rats with acute ischemic stroke complicated with chronic renal failure.
Sun R, Gu Q, Zhang X, Zeng R, Chen D, Yao J, Min J
Toxicological research 2024 Apr;40(2):189-202
Toxicological research 2024 Apr;40(2):189-202
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Liu X, Liu M, Chen L
Cell and tissue research 2024 Apr;396(1):103-117
Cell and tissue research 2024 Apr;396(1):103-117
Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology.
Liu K, Yin Y, Shi C, Yan C, Zhang Y, Qiu L, He S, Li G
Phytotherapy research : PTR 2024 Apr;38(4):2023-2040
Phytotherapy research : PTR 2024 Apr;38(4):2023-2040
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
Yu X, Nie W, Chen X, Zou LF, Xu BC, Chen CG
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
L-theanine attenuates H(2)O(2)-induced inflammation and apoptosis in IPEC-J2 cells via inhibiting p38 MAPK signaling pathway.
Li Z, Huang Z, Jia G, Zhao H, Liu G, Chen X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114561
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114561
Trilobatin attenuates cerebral ischaemia/reperfusion-induced blood-brain barrier dysfunction by targeting matrix metalloproteinase 9: The legend of a food additive.
Feng L, Li Y, Lin M, Xie D, Luo Y, Zhang Y, He Z, Gong Q, Zhun ZY, Gao J
British journal of pharmacology 2024 Apr;181(7):1005-1027
British journal of pharmacology 2024 Apr;181(7):1005-1027
A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease.
Saviano A, Schettino A, Iaccarino N, Mansour AA, Begum J, Marigliano N, Raucci F, Romano F, Riccardi G, Mitidieri E, d'Emmanuele di Villa Bianca R, Bello I, Panza E, Smimmo M, Vellecco V, Rimmer P, Cheesbrough J, Zhi Z, Iqbal TH, Pieretti S, D'Amore VM, Marinelli L, La Pietra V, Sorrentino R, Costa L, Caso F, Scarpa R, Cirino G, Randazzo A, Bucci M, McGettrick HM, Iqbal AJ, Maione F
Journal of autoimmunity 2024 Apr;144:103181
Journal of autoimmunity 2024 Apr;144:103181
Alleviation of allergic asthma by rosmarinic acid via gut-lung axis.
Guo HH, Han YX, Rong XJ, Shen Z, Shen HR, Kong LF, Guo YD, Li JZ, Xu B, Gao TL, Wang LL, Tie C, Jiang JD
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155470
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155470
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
Zhang L, Miao C, Wang Z, Guan X, Ma Y, Song J, Shen S, Song H, Li M, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
Occludin and collagen IV degradation mediated by the T9SS effector SspA contributes to blood-brain barrier damage in ducks during Riemerella anatipestifer infection.
Chen Z, Zhu M, Liu D, Wu M, Niu P, Yu Y, Ding C, Yu S
Veterinary research 2024 Apr 9;55(1):49
Veterinary research 2024 Apr 9;55(1):49
Faecalibacterium prausnitzii Supplementation Prevents Intestinal Barrier Injury and Gut Microflora Dysbiosis Induced by Sleep Deprivation.
Wang X, Li Y, Wang X, Wang R, Hao Y, Ren F, Wang P, Fang B
Nutrients 2024 Apr 9;16(8)
Nutrients 2024 Apr 9;16(8)
Exploring the mechanism of Bushen Huoxue prescription in the treatment of early diabetic retinal edema from the perspective of inner blood-retinal barrier injury.
Li J, Guo X, Huang Y, Ren Y, Liang H, Xie X, Zhang M
Journal of ethnopharmacology 2024 Apr 6;323:117658
Journal of ethnopharmacology 2024 Apr 6;323:117658
Canagliflozin protects against hyperglycemia-induced cerebrovascular injury by preventing blood-brain barrier (BBB) disruption via AMPK/Sp1/adenosine A2A receptor.
Liu Z, Hua W, Jin S, Wang Y, Pang Y, Wang B, Zhao N, Song Y, Qi J
European journal of pharmacology 2024 Apr 5;968:176381
European journal of pharmacology 2024 Apr 5;968:176381
The Lactobacillus plantarum P-8 Probiotic Microcapsule Prevents DSS-Induced Colitis through Improving Intestinal Integrity and Reducing Colonic Inflammation in Mice.
Wang H, Sun Y, Ma X, Yang T, Wang F
Nutrients 2024 Apr 4;16(7)
Nutrients 2024 Apr 4;16(7)
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Wang L, Yan M, Bu T, Wu X, Li L, Silvestrini B, Sun F, Cheng CY, Chen H
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Bone-derived PDGF-BB enhances hippocampal non-specific transcytosis through microglia-endothelial crosstalk in HFD-induced metabolic syndrome.
Liu G, Shu W, Chen Y, Fu Y, Fang S, Zheng H, Cheng W, Lin Q, Hu Y, Jiang N, Yu B
Journal of neuroinflammation 2024 Apr 29;21(1):111
Journal of neuroinflammation 2024 Apr 29;21(1):111
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Bu T, Wang L, Wu X, Gao S, Li X, Yun D, Yang X, Li L, Cheng CY, Sun F
Endocrinology 2024 Apr 29;165(6)
Endocrinology 2024 Apr 29;165(6)
Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines.
Zou J, Chen Q, He Y, Pan Y, Zhao H, Shi J, Wei Z, Yu S, Zhao Y, Han X, Lu Y, Chen W
BMC cancer 2024 Apr 23;24(1):507
BMC cancer 2024 Apr 23;24(1):507
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
Wen Z, Fan J, Zhan F, Li X, Li B, Lu P, Yao X, Shen Z, Liu Z, Wang C, Li X, Jin W, Zhang X, Qi Y, Wang X, Song M
International immunopharmacology 2024 Apr 20;131:111911
International immunopharmacology 2024 Apr 20;131:111911
miR-186-5p improves alveolar epithelial barrier function by targeting the wnt5a/β-catenin signaling pathway in sepsis-acute lung injury.
Li M, Yang J, Wu Y, Ma X
International immunopharmacology 2024 Apr 20;131:111864
International immunopharmacology 2024 Apr 20;131:111864
Acupuncture Extended the Thrombolysis Window by Suppressing Blood-Brain Barrier Disruption and Regulating Autophagy-Apoptosis Balance after Ischemic Stroke.
Zhang Z, Lu T, Li S, Zhao R, Li H, Zhang X, Li Y, Xia Y, Ni G
Brain sciences 2024 Apr 19;14(4)
Brain sciences 2024 Apr 19;14(4)
Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway.
Xia S, Yan C, Gu J, Yuan Y, Zou H, Liu Z, Bian J
Foods (Basel, Switzerland) 2024 Apr 17;13(8)
Foods (Basel, Switzerland) 2024 Apr 17;13(8)
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Hu W, Zhai ZY, Huang ZY, Chen ZM, Zhou P, Li XX, Yang GH, Bao CJ, You LJ, Cui XB, Xia GL, Ou Yang MP, Zhang L, Wu WKK, Li LF, Zhang YX, Xiao ZG, Gong W
mSystems 2024 Apr 16;9(4):e0020624
mSystems 2024 Apr 16;9(4):e0020624
Long-Term Triclocarban Exposure Induced Enterotoxicity by Triggering Intestinal AhR-Mediated Inflammation and Disrupting Microbial Community in Mice.
Song Y, Lei H, Cao Z, Zhang C, Chen C, Wu M, Zhang H, Du R, Lijun L, Chen X, Zhang L
Chemical research in toxicology 2024 Apr 15;37(4):658-668
Chemical research in toxicology 2024 Apr 15;37(4):658-668
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Peng Z, Ding YN, Yang ZM, Li XJ, Zhuang Z, Lu Y, Tang QS, Hang CH, Li W
Acta biomaterialia 2024 Apr 15;179:325-339
Acta biomaterialia 2024 Apr 15;179:325-339
Microneedle array facilitates hepatic sinusoid construction in a large-scale liver-acinus-chip microsystem.
Li S, Li C, Khan MI, Liu J, Shi Z, Gao D, Qiu B, Ding W
Microsystems & nanoengineering 2023;9:75
Microsystems & nanoengineering 2023;9:75
Caulerpa lentillifera improves ethanol-induced liver injury and modulates the gut microbiota in rats.
Lin KY, Yang HY, Yang SC, Chen YL, Watanabe Y, Chen JR
Current research in food science 2023;7:100546
Current research in food science 2023;7:100546
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
Hao Z, Zhang Z, Zhao Y, Wang D
The American journal of Chinese medicine 2023;51(2):355-372
The American journal of Chinese medicine 2023;51(2):355-372
Panax notoginseng Alleviates Colitis via the Regulation of Gut Microbiota.
Wang L, Shao L, Chen MY, Wang L, Yang P, Tan FB, Zhang W, Huang WH
The American journal of Chinese medicine 2023;51(1):107-127
The American journal of Chinese medicine 2023;51(1):107-127
Functional Peptide-Modified Liposomes for siRNA Delivery to Rat Retinal Pigment Epithelium Cells: Effect of Peptide Sequences.
Nishida S, Takashima Y, Endo K, Ishihara H
Biological & pharmaceutical bulletin 2023;46(10):1468-1478
Biological & pharmaceutical bulletin 2023;46(10):1468-1478
Butylphthalide improves brain damage induced by renal ischemia-reperfusion injury rats through Nrf2/HO-1 and NOD2/MAPK/NF-κB pathways.
Min J, Chen Q, Pan M, Liu T, Gu Q, Zhang D, Sun R
Renal failure 2023;45(2):2259234
Renal failure 2023;45(2):2259234
A microfluidic thyroid-liver platform to assess chemical safety in humans.
Kühnlenz J, Karwelat D, Steger-Hartmann T, Raschke M, Bauer S, Vural Ö, Marx U, Tinwell H, Bars R
ALTEX 2023;40(1):61-82
ALTEX 2023;40(1):61-82
Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle.
Li LZ, Wang XM, Feng XJ, Liu K, Li B, Zhu LJ, Xu WF, Zheng X, Dong YJ, He XL, Guan HR, Ding YY, Wu HS, Zhou CJ, Ye SY, Zhang BB, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2023;2023:9990843
Evidence-based complementary and alternative medicine : eCAM 2023;2023:9990843
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Chen Y, Zhang H, Li Y, Wang T
Oxidative medicine and cellular longevity 2023;2023:8258354
Oxidative medicine and cellular longevity 2023;2023:8258354
Upregulated SSB Is Involved in Hepatocellular Carcinoma Progression and Metastasis through the Epithelial-Mesenchymal Transition, Antiapoptosis, and Altered ROS Level Pathway.
Wu H, Zhang Z, Han X, Zhang S, Zhang J, Han P, Zhang Y, Bai Y, Zhang Y
Oxidative medicine and cellular longevity 2023;2023:5207431
Oxidative medicine and cellular longevity 2023;2023:5207431
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
Zhou H, Zhang Q, Huang W, Zhou S, Wang Y, Zeng X, Wang H, Xie W, Kong H
International journal of biological sciences 2023;19(6):1875-1893
International journal of biological sciences 2023;19(6):1875-1893
A hydrogel model of the human blood-brain barrier using differentiated stem cells.
Singh NR, Gromnicova R, Brachner A, Kraev I, Romero IA, Neuhaus W, Male D
PloS one 2023;18(4):e0283954
PloS one 2023;18(4):e0283954
Shensong Yangxin Capsule Reduces the Susceptibility of Arrhythmia in db/db Mice via Inhibiting the Inflammatory Response Induced by Endothelium Dysfunction.
Zhang J, Li H, Wang D, Gu J, Hou Y, Wu Y
Drug design, development and therapy 2023;17:313-330
Drug design, development and therapy 2023;17:313-330
Indole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Experimental Colitis Models.
Wang M, Guo J, Hart AL, Li JV
Journal of inflammation research 2023;16:5845-5864
Journal of inflammation research 2023;16:5845-5864
Suppression of Wnt/β-catenin Signaling in PDAC via METTL16-mediated N6-methyladenosine Modification of DVL2.
Yu L, Lu J, Xie N, Fang L, Chen S, Wu Y, Wang X, Li B
Journal of Cancer 2023;14(16):2964-2977
Journal of Cancer 2023;14(16):2964-2977
Bacteroides acidifaciens and its derived extracellular vesicles improve DSS-induced colitis.
Zheng C, Zhong Y, Xie J, Wang Z, Zhang W, Pi Y, Zhang W, Liu L, Luo J, Xu W
Frontiers in microbiology 2023;14:1304232
Frontiers in microbiology 2023;14:1304232
The immunity protection of intestine induced by pseudorabies virus del gI/gE/TK in piglets.
Zhang Y, Xu L, Tao Q, Liu Z, Wen J, Xu T, Lai S, Ai Y, Xu Z, Zhu L
Frontiers in microbiology 2023;14:1295524
Frontiers in microbiology 2023;14:1295524
Leveraging a gene signature associated with disulfidptosis identified by machine learning to forecast clinical outcomes, immunological heterogeneities, and potential therapeutic targets within lower-grade glioma.
Zhou Y, Cao Y, Liu W, Wang L, Kuang Y, Zhou Y, Chen Q, Cheng Z, Huang H, Zhang W, Jiang X, Wang B, Ren C
Frontiers in immunology 2023;14:1294459
Frontiers in immunology 2023;14:1294459
Fecal microbiota transplantation from HUC-MSC-treated mice alleviates acute lung injury in mice through anti-inflammation and gut microbiota modulation.
Hua F, Cui E, Lv L, Wang B, Li L, Lu H, Chen N, Chen W
Frontiers in microbiology 2023;14:1243102
Frontiers in microbiology 2023;14:1243102
β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis.
Zhang D, Ge F, Ji J, Li YJ, Zhang FR, Wang SY, Zhang SJ, Zhang DM, Chen M
Frontiers in pharmacology 2023;14:1218477
Frontiers in pharmacology 2023;14:1218477
Ultrasound-assisted intravesical botulinum toxin A delivery attenuates acetic acid-induced bladder hyperactivity in rats.
Liu Q, Gao Y, Cong H, Liao L
Frontiers in pharmacology 2023;14:1214145
Frontiers in pharmacology 2023;14:1214145
Mahuang Fuzi Xixin decoction ameliorates allergic rhinitis and repairs the airway epithelial barrier by modulating the lung microbiota dysbiosis.
Wei X, Ding M, Liang X, Zhang B, Tan X, Zheng Z
Frontiers in microbiology 2023;14:1206454
Frontiers in microbiology 2023;14:1206454
Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness.
Mu Y, Wei D, Yao L, Xu X, Li S, Cao R, Chen T, Zhang Z
Frontiers in physiology 2023;14:1198862
Frontiers in physiology 2023;14:1198862
Intermittent fasting protects against food allergy in a murine model via regulating gut microbiota.
Ma RX, Hu JQ, Fu W, Zhong J, Cao C, Wang CC, Qi SQ, Zhang XL, Liu GH, Gao YD
Frontiers in immunology 2023;14:1167562
Frontiers in immunology 2023;14:1167562
Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.
Zhang P, Chen J, Ming Y, Niu Y
Frontiers in microbiology 2023;14:1153188
Frontiers in microbiology 2023;14:1153188
Circulating sepsis-related metabolite sphinganine could protect against intestinal damage during sepsis.
Wang Z, Qi Y, Wang F, Zhang B, Jianguo T
Frontiers in immunology 2023;14:1151728
Frontiers in immunology 2023;14:1151728
Whole intestinal microbiota transplantation is more effective than fecal microbiota transplantation in reducing the susceptibility of DSS-induced germ-free mice colitis.
Yang Y, He J, Wang Y, Liang L, Zhang Z, Tan X, Tao S, Wu Z, Dong M, Zheng J, Zhang H, Feng S, Cheng W, Chen Q, Wei H
Frontiers in immunology 2023;14:1143526
Frontiers in immunology 2023;14:1143526
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Wang F, Qian F, Zhang Q, Zhao J, Cen J, Zhang J, Zhou J, Luo M, Jia C, Rong X, Chu M
Frontiers in immunology 2023;14:1124118
Frontiers in immunology 2023;14:1124118
Zengshengping improves lung cancer by regulating the intestinal barrier and intestinal microbiota.
Sun E, Meng X, Kang Z, Gu H, Li M, Tan X, Feng L, Jia X
Frontiers in pharmacology 2023;14:1123819
Frontiers in pharmacology 2023;14:1123819
Establishment of a porcine bronchial epithelial cell line and its application to study innate immunity in the respiratory epithelium.
Fukuyama K, Zhuang T, Toyoshi E, Raya Tonetti F, Saha S, Zhou B, Ikeda-Ohtsubo W, Nishiyama K, Aso H, Villena J, Kitazawa H
Frontiers in immunology 2023;14:1117102
Frontiers in immunology 2023;14:1117102
Network pharmacology and experimental study of phenolic acids in salvia miltiorrhiza bung in preventing ischemic stroke.
Liu C, Du L, Zhang S, Wang H, Kong L, Du G
Frontiers in pharmacology 2023;14:1108518
Frontiers in pharmacology 2023;14:1108518
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
Ding S, Cheng Y, Azad MAK, Dong H, He J, Huang P, Kong X
Frontiers in immunology 2023;14:1104837
Frontiers in immunology 2023;14:1104837
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Ma P, Huang N, Tang J, Zhou Z, Xu J, Chen Y, Zhang M, Huang Q, Cheng Y
Frontiers in pharmacology 2023;14:1098228
Frontiers in pharmacology 2023;14:1098228
Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury.
Jia J, Deng J, Jin H, Yang J, Nan D, Yu Z, Yu W, Shen Z, Lu Y, Liu R, Wang Z, Qu X, Qiu D, Yang Z, Huang Y
Frontiers in pharmacology 2023;14:1084564
Frontiers in pharmacology 2023;14:1084564
Jinhong decoction protects sepsis-associated acute lung injury by reducing intestinal bacterial translocation and improving gut microbial homeostasis.
Bao K, Wang M, Liu L, Zhang D, Jin C, Zhang J, Shi L
Frontiers in pharmacology 2023;14:1079482
Frontiers in pharmacology 2023;14:1079482
Wnt4 increases the thickness of the epidermis in burn wounds by activating canonical Wnt signalling and decreasing the cell junctions between epidermal cells.
Xiang F, Wang P, Gong H, Luo J, Zhou X, Zhan C, Hu T, Wang M, Xing Y, Guo H, Luo G, Li Y
Burns & trauma 2023;11:tkac053
Burns & trauma 2023;11:tkac053
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ge L, Wang K, Lin H, Tao E, Xia W, Wang F, Mao C, Feng Y
Frontiers in bioengineering and biotechnology 2023;11:1129538
Frontiers in bioengineering and biotechnology 2023;11:1129538
Efficient Therapy of Inflammatory Bowel Disease (IBD) with Highly Specific and Durable Targeted Ta(2) C Modified with Chondroitin Sulfate (TACS).
Song X, Huang Q, Yang Y, Ma L, Liu W, Ou C, Chen Q, Zhao T, Xiao Z, Wang M, Jiang Y, Yang Y, Zhang J, Nan Y, Wu W, Ai K
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(36):e2301585
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(36):e2301585
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Li T, Tang Q, Xu J, Ye X, Chen K, Zhong J, Zhu J, Lu S, Zhu T
Stem cells and development 2023 Sep;32(17-18):539-553
Stem cells and development 2023 Sep;32(17-18):539-553
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
Li Q, Yang Q, Guo P, Feng Y, Wang S, Guo J, Tang Z, Yu W, Liao J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury.
Xu B, Fang J, Wang J, Jin X, Liu S, Song K, Wang P, Liu J, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115165
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115165
Lactiplantibacillus plantarum L47 and inulin alleviate enterotoxigenic Escherichia coli induced ileal inflammation in piglets by upregulating the levels of α-linolenic acid and 12,13-epoxyoctadecenoic acid.
Cui L, Zeng H, Hou M, Li Z, Mu C, Zhu W, Hang S
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:370-382
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:370-382
Dietary emodin alleviates lipopolysaccharide-induced intestinal mucosal barrier injury by regulating gut microbiota in piglets.
Xun W, Ji M, Ma Z, Deng T, Yang W, Hou G, Shi L, Cao T
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:152-162
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:152-162
Maslinic acid alleviates LPS-induced mice mastitis by inhibiting inflammatory response, maintaining the integrity of the blood-milk barrier and regulating intestinal flora.
Li K, Ran X, Zeng Y, Li S, Hu G, Wang X, Li Y, Yang Z, Liu J, Fu S
International immunopharmacology 2023 Sep;122:110551
International immunopharmacology 2023 Sep;122:110551
Maintenance of airway epithelial barrier integrity via the inhibition of AHR/EGFR activation ameliorates chronic obstructive pulmonary disease using effective-component combination.
Wei Y, Liu X, Jiang Y, Guan Q, Tian Y, Li J, Zhao P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154980
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154980
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
Chen J, Liu X, Bi R, Liu P, Gong W
Neuroreport 2023 Sep 6;34(13):670-676
Neuroreport 2023 Sep 6;34(13):670-676
The panda-derived Lactiplantibacillus plantarum BSG201683 improves LPS-induced intestinal inflammation and epithelial barrier disruption in vitro.
Zhou Y, Duan L, Zeng Y, Song X, Pan K, Niu L, Pu Y, Li J, Khalique A, Fang J, Jing B, Zeng D, Shen B, Ni X
BMC microbiology 2023 Sep 6;23(1):249
BMC microbiology 2023 Sep 6;23(1):249
A novel small molecule effectively ameliorates estrogen deficiency-induced osteoporosis by targeting the gut-bone signaling axis.
Chen C, Lei H, Zhao Y, Hou Y, Zheng H, Zhang C, Cao Z, Wu F, Chen G, Song Y, Zhang C, Zhou J, Lu Y, Xie D, Zhang L
European journal of pharmacology 2023 Sep 5;954:175868
European journal of pharmacology 2023 Sep 5;954:175868
Gut microbiota modulate distal symmetric polyneuropathy in patients with diabetes.
Yang J, Yang X, Wu G, Huang F, Shi X, Wei W, Zhang Y, Zhang H, Cheng L, Yu L, Shang J, Lv Y, Wang X, Zhai R, Li P, Cui B, Fang Y, Deng X, Tang S, Wang L, Yuan Q, Zhao L, Zhang F, Zhang C, Yuan H
Cell metabolism 2023 Sep 5;35(9):1548-1562.e7
Cell metabolism 2023 Sep 5;35(9):1548-1562.e7
The mechanism of simultaneous intake of Jujuboside A and B in the regulation of sleep at the hypothalamic level.
Wang W, Wang Y, Pei H, Li M, Zhu A, Du R, Peng GJ
Aging 2023 Sep 5;15(18):9426-9437
Aging 2023 Sep 5;15(18):9426-9437
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Lei P, Li Z, Hua Q, Song P, Gao L, Zhou L, Cai Q
International journal of molecular sciences 2023 Sep 30;24(19)
International journal of molecular sciences 2023 Sep 30;24(19)
Sea Conch Peptides Hydrolysate Alleviates DSS-Induced Colitis in Mice through Immune Modulation and Gut Microbiota Restoration.
Ullah H, Deng T, Ali M, Farooqui NA, Alsholi DM, Siddiqui NZ, Rehman AU, Ali S, Ilyas M, Wang L, Xin Y
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
Long-term PM2.5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models.
Hao S, Chen Z, Gu Y, Chen L, Sheng F, Xu Y, Wu D, Han Y, Lu B, Chen S, Zhao W, Yin H, Wang X, Riazuddin SA, Lou X, Fu Q, Yao K
Particle and fibre toxicology 2023 Sep 27;20(1):36
Particle and fibre toxicology 2023 Sep 27;20(1):36
Multiomics reveal human umbilical cord mesenchymal stem cells improving acute lung injury via the lung-gut axis.
Lv L, Cui EH, Wang B, Li LQ, Hua F, Lu HD, Chen N, Chen WY
World journal of stem cells 2023 Sep 26;15(9):908-930
World journal of stem cells 2023 Sep 26;15(9):908-930
Fasting-mimicking diet alleviates inflammatory pain by inhibiting neutrophil extracellular traps formation and neuroinflammation in the spinal cord.
Li T, Yue Y, Ma Y, Zhong Z, Guo M, Zhang J, Wang Z, Miao C
Cell communication and signaling : CCS 2023 Sep 21;21(1):250
Cell communication and signaling : CCS 2023 Sep 21;21(1):250
Pterostilbene alleviated cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction via inhibiting early endothelial cytoskeleton reorganization and late basement membrane degradation.
Yang ZH, Liu YJ, Ban WK, Liu HB, Lv LJ, Zhang BY, Liu AL, Hou ZY, Lu J, Chen X, You YY
Food & function 2023 Sep 19;14(18):8291-8308
Food & function 2023 Sep 19;14(18):8291-8308
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Wang Y, Zhang J, Zhang B, Lu M, Ma J, Liu Z, Huang J, Ma J, Yang X, Wang F, Tang X
Journal of ethnopharmacology 2023 Sep 15;313:116538
Journal of ethnopharmacology 2023 Sep 15;313:116538
Effects of DON on Mitochondrial Function, Endoplasmic Reticulum Stress, and Endoplasmic Reticulum Mitochondria Contact Sites in the Jejunum of Piglets.
Li X, Gou F, Xiao K, Zhu J, Lin Q, Yu M, Hong Q, Hu C
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13234-13243
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13234-13243
Catalysis-Mediated Male Contraception through Black Phosphorus Nanosheets.
Yi L, Zhu S, Wu P, Zhang Y, Wang M, Xu P, Zeng J, Wang G, Luo L, Li W
ACS applied materials & interfaces 2023 Sep 13;15(36):42284-42292
ACS applied materials & interfaces 2023 Sep 13;15(36):42284-42292
Cerebrospinal Fluid Pressure Reduction Induces Glia-Mediated Retinal Inflammation and Leads to Retinal Ganglion Cell Injury in Rats.
Cheng Y, Lin D, Wu S, Liu Q, Yan X, Ren T, Zhang J, Wang N
Molecular neurobiology 2023 Oct;60(10):5770-5788
Molecular neurobiology 2023 Oct;60(10):5770-5788
The therapeutic value of adipose-derived pericyte transplantation after intracerebral hemorrhage in rats.
Zhang X, Zhou Y, Liu Q, Wang F, Fu L, Wei Y, Ye Y, Guo Y
Journal of molecular histology 2023 Oct;54(5):499-508
Journal of molecular histology 2023 Oct;54(5):499-508
Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans.
Zong X, Zhang H, Zhu L, Deehan EC, Fu J, Wang Y, Jin M
Journal of advanced research 2023 Oct;52:203-218
Journal of advanced research 2023 Oct;52:203-218
Oncogenic BRAF noncanonically promotes tumor metastasis by mediating VASP phosphorylation and filopodia formation.
Pan W, Tian Y, Zheng Q, Yang Z, Qiang Y, Zhang Z, Zhang N, Xiong J, Zhu X, Wei L, Li F
Oncogene 2023 Oct;42(43):3194-3205
Oncogene 2023 Oct;42(43):3194-3205
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Bian Y, Yin G, Wang G, Liu T, Liang L, Yang X, Zhang W, Tang D
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Repeated Social Defeat Stress Induces an Inflammatory Gut Milieu by Altering the Mucosal Barrier Integrity and Gut Microbiota Homeostasis.
Yadav SK, Ahmad R, Moshfegh CM, Sankarasubramanian J, Joshi V, Elkhatib SK, Chhonker YS, Murry DJ, Talmon GA, Guda C, Case AJ, Singh AB
Biological psychiatry global open science 2023 Oct;3(4):824-836
Biological psychiatry global open science 2023 Oct;3(4):824-836
Lactiplantibacillus plantarum Strain FLPL05 Promotes Longevity in Mice by Improving Intestinal Barrier.
Yu X, Wei M, Yang D, Wu X, Wei H, Xu F
Probiotics and antimicrobial proteins 2023 Oct;15(5):1193-1205
Probiotics and antimicrobial proteins 2023 Oct;15(5):1193-1205
3D Bioprinting of Neurovascular Tissue Modeling with Collagen-Based Low-Viscosity Composites.
Wang S, Bai L, Hu X, Yao S, Hao Z, Zhou J, Li X, Lu H, He J, Wang L, Li D
Advanced healthcare materials 2023 Oct;12(25):e2300004
Advanced healthcare materials 2023 Oct;12(25):e2300004
Chlorogenic Acid Ameliorates Post-Infectious Irritable Bowel Syndrome by Regulating Extracellular Vesicles of Gut Microbes.
Zheng C, Zhong Y, Zhang W, Wang Z, Xiao H, Zhang W, Xie J, Peng X, Luo J, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2302798
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2302798
Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease.
Haferkamp U, Hartmann C, Abid CL, Brachner A, Höchner A, Gerhartl A, Harwardt B, Leckzik S, Leu J, Metzger M, Nastainczyk-Wulf M, Neuhaus W, Oerter S, Pless O, Rujescu D, Jung M, Appelt-Menzel A
Fluids and barriers of the CNS 2023 Oct 31;20(1):78
Fluids and barriers of the CNS 2023 Oct 31;20(1):78
Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism.
Li F, Zhang Z, Bai Y, Che Q, Cao H, Guo J, Su Z
Molecules (Basel, Switzerland) 2023 Oct 3;28(19)
Molecules (Basel, Switzerland) 2023 Oct 3;28(19)
Dietary Betaine Supplementation Enhances Colonic Barrier Function through the Nrf2/Keap1 and TLR4-NF-κB/MAPK Signaling Pathways and Alters Colonic Microbiota in Bama Mini-Pigs.
Xiong L, Wang K, Song M, Azad MAK, Zhu Q, Kong X
Antioxidants (Basel, Switzerland) 2023 Oct 29;12(11)
Antioxidants (Basel, Switzerland) 2023 Oct 29;12(11)
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Li H, Zhang C, Zhou Y, Deng Y, Zheng X, Xue X
Aging 2023 Oct 26;15(20):11639-11653
Aging 2023 Oct 26;15(20):11639-11653
Atractylodes lancea Rhizome Polysaccharide Alleviates Immunosuppression and Intestinal Mucosal Injury in Mice Treated with Cyclophosphamide.
Wang D, Dong Y, Xie Y, Xiao Y, Ke C, Shi K, Zhou Z, Tu J, Qu L, Liu Y
Journal of agricultural and food chemistry 2023 Oct 20;
Journal of agricultural and food chemistry 2023 Oct 20;
FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.
Guan X, Wei D, Liang Z, Xie L, Wang Y, Huang Z, Wu J, Pang T
ACS chemical neuroscience 2023 Oct 18;14(20):3839-3854
ACS chemical neuroscience 2023 Oct 18;14(20):3839-3854
Effect of Cordyceps militaris Powder Prophylactic Supplementation on Intestinal Mucosal Barrier Impairment and Microbiota-Metabolites Axis in DSS-Injured Mice.
Wu S, Wu Z, Chen Y
Nutrients 2023 Oct 16;15(20)
Nutrients 2023 Oct 16;15(20)
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis.
Chen F, Wang S, Zeng C, Tang S, Gu H, Wang Z, Li J, Feng P, Zhang Y, Wang P, Wu Y, Shen H
Cellular and molecular life sciences : CMLS 2023 Oct 13;80(11):325
Cellular and molecular life sciences : CMLS 2023 Oct 13;80(11):325
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Tung TH, Lai WD, Lee HC, Su KP, Panunggal B, Huang SY
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Effects of Enteromorpha prolifera polysaccharides on growth performance, intestinal barrier function and cecal microbiota in yellow-feathered broilers under heat stress.
Liu W, Liu H, Wang Y, Zhao Z, Balasubramanian B, Jha R
Journal of animal science and biotechnology 2023 Oct 10;14(1):132
Journal of animal science and biotechnology 2023 Oct 10;14(1):132
miR-379-5P INHIBITION ENHANCES INTESTINAL EPITHELIAL PROLIFERATION AND BARRIER FUNCTION RECOVERY AFTER ISCHEMIA/REPERFUSION BY TARGETING EIF4G2.
Jia Z, Wang Y, Gao J, Zheng M, Wang P, Zu G
Shock (Augusta, Ga.) 2023 Oct 1;60(4):594-602
Shock (Augusta, Ga.) 2023 Oct 1;60(4):594-602
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
The coexistence of aflatoxin M1 and ochratoxin A induced intestinal barrier disruption via the regulation of key differentially expressed microRNAs and long non-coding RNAs in BALB/c mice.
Gao YN, Min L, Yang X, Wang JQ, Zheng N
Ecotoxicology and environmental safety 2023 Oct 1;264:115428
Ecotoxicology and environmental safety 2023 Oct 1;264:115428
Nickel induces blood-testis barrier damage through ROS-mediated p38 MAPK pathways in mice.
Zeng Y, Yang Q, Ouyang Y, Lou Y, Cui H, Deng H, Zhu Y, Geng Y, Ouyang P, Chen L, Zuo Z, Fang J, Guo H
Redox biology 2023 Nov;67:102886
Redox biology 2023 Nov;67:102886
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Wang Y, Qiao M, Yao X, Feng Z, Hu R, Chen J, Liu L, Liu J, Sun Y, Guo Y
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Dendrobium huoshanense Polysaccharide Improves High-Fat Diet Induced Liver Injury by Regulating the Gut-Liver Axis.
Ma MH, Gao LL, Chen CB, Gu FL, Wu SQ, Li F, Han BX
Chemistry & biodiversity 2023 Nov;20(11):e202300980
Chemistry & biodiversity 2023 Nov;20(11):e202300980
Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis.
Chen T, Zhang L, Yao L, Luan J, Zhou X, Cong R, Guo X, Qin C, Song N
Environment international 2023 Nov;181:108292
Environment international 2023 Nov;181:108292
Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury.
Li W, Zhao X, Zhang R, Liu X, Qi Z, Zhang Y, Yang W, Pang Y, Zhao C, Fan B, Ran N, Zhang J, Kong X, Feng S, Yao X
Neural regeneration research 2023 Nov;18(11):2474-2481
Neural regeneration research 2023 Nov;18(11):2474-2481
Refined Qingkailing protects the in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.
Ren Z, Chen C, Zheng Y, Zhang S, Yan J, Cheng F, Wang X, Wang Q, Li C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115580
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115580
Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice.
Xiang XH, Wei J, Wang XF, Xu Q, Yu CL, He CL, Long T, Guo MS, Chen X, Zhou XG, Wu JM, Qin DL, Wu AG, Tang Y, Lv HB
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115478
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115478
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
Liu H, Xi Q, Tan S, Qu Y, Meng Q, Zhang Y, Cheng Y, Wu G
International immunopharmacology 2023 Nov;124(Pt B):111001
International immunopharmacology 2023 Nov;124(Pt B):111001
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Sun X, Liu Z, Zhou L, Ma R, Zhang X, Wang T, Fu F, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155071
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155071
Cingulin regulates hair cell cuticular plate morphology and is required for hearing in human and mouse.
Zhu GJ, Huang Y, Zhang L, Yan K, Qiu C, He Y, Liu Q, Zhu C, Morín M, Moreno-Pelayo MÁ, Zhu MS, Cao X, Zhou H, Qian X, Xu Z, Chen J, Gao X, Wan G
EMBO molecular medicine 2023 Nov 8;15(11):e17611
EMBO molecular medicine 2023 Nov 8;15(11):e17611
JNK regulates ciliogenesis through the interflagellar transport complex and actin networks.
Chatzifrangkeskou M, Kouis P, Skourides PA
The Journal of cell biology 2023 Nov 6;222(11)
The Journal of cell biology 2023 Nov 6;222(11)
Quercetin Attenuates the Combined Effects of Zearalenone and Lipopolysaccharide on IPEC-J2 Cell Injury through Activating the Nrf2 Signaling Pathway.
Wang C, Fu Y, Wang R, Wang Q, Yu H, Zhang J
Toxins 2023 Nov 30;15(12)
Toxins 2023 Nov 30;15(12)
Cadmium promotes colorectal cancer metastasis through EGFR/Akt/mTOR signaling cascade and dynamics.
Sun M, Jiang Z, Gu P, Guo B, Li J, Cheng S, Ba Q, Wang H
The Science of the total environment 2023 Nov 15;899:165699
The Science of the total environment 2023 Nov 15;899:165699
Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.
Wei H, Zhen L, Wang S, Yang L, Zhang S, Zhang Y, Jia P, Wang T, Wang K, Zhang Y, Ma L, Lv J, Zhang P
Journal of neuroinflammation 2023 Nov 15;20(1):264
Journal of neuroinflammation 2023 Nov 15;20(1):264
Environmental cadmium exposure facilitates mammary tumorigenesis via reprogramming gut microbiota-mediated glutamine metabolism in MMTV-Erbb2 mice.
Yue Y, Zhang H, Deng P, Tan M, Chen C, Tang B, Li J, Chen F, Zhao Q, Li L, Hao R, Wang H, Luo Y, Tian L, Xie J, Chen M, Yu Z, Zhou Z, Pi H
The Science of the total environment 2023 Nov 1;897:165348
The Science of the total environment 2023 Nov 1;897:165348
Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling.
Li N, Wang R, Li W, Du Q, Deng Z, Fan Y, Zheng L
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16057-16066
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16057-16066
Phlorizin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota and Inhibiting Ferroptosis.
Cheng J, Liu D, Huang Y, Chen L, Li Y, Yang Z, Fu S, Hu G
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16043-16056
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16043-16056
Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice.
Wu M, Chen C, Lei H, Cao Z, Zhang C, Du R, Zhang C, Song Y, Qin M, Zhou J, Lu Y, Wang X, Zhang L
Journal of agricultural and food chemistry 2023 Nov 1;71(43):15981-15990
Journal of agricultural and food chemistry 2023 Nov 1;71(43):15981-15990
Bile Acid Derivatives Effectively Prevented High-Fat Diet-Induced Colonic Barrier Dysfunction.
Ma Y, Shan K, Huang Z, Zhao D, Zhang M, Ke W, Li C
Molecular nutrition & food research 2023 May;67(10):e2200649
Molecular nutrition & food research 2023 May;67(10):e2200649
Comparative study of cigarette smoke, Klebsiella pneumoniae, and their combination on airway epithelial barrier function in mice.
Li K, Mei X, Xu K, Jia L, Zhao P, Tian Y, Li J
Environmental toxicology 2023 May;38(5):1133-1142
Environmental toxicology 2023 May;38(5):1133-1142
Interleukin-1β suppresses rabies virus infection by activating cGAS-STING pathway and compromising the blood-brain barrier integrity in mice.
Wu D, Wang J, Huang C, Zhao J, Fu ZF, Zhao L, Zhou M
Veterinary microbiology 2023 May;280:109708
Veterinary microbiology 2023 May;280:109708
Globoside and the mucosal pH mediate parvovirus B19 entry through the epithelial barrier.
Suter C, Colakovic M, Bieri J, Gultom M, Dijkman R, Ros C
PLoS pathogens 2023 May;19(5):e1011402
PLoS pathogens 2023 May;19(5):e1011402
Oral Metal-Free Melanin Nanozymes for Natural and Durable Targeted Treatment of Inflammatory Bowel Disease (IBD).
Huang Q, Yang Y, Zhu Y, Chen Q, Zhao T, Xiao Z, Wang M, Song X, Jiang Y, Yang Y, Zhang J, Xiao Y, Nan Y, Wu W, Ai K
Small (Weinheim an der Bergstrasse, Germany) 2023 May;19(19):e2207350
Small (Weinheim an der Bergstrasse, Germany) 2023 May;19(19):e2207350
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Ma N, Ma D, Liu X, Zhao L, Ma L, Ma D, Dong S
Environment international 2023 May;175:107949
Environment international 2023 May;175:107949
Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.
Zhang M, Xiong Y, Tu J, Tang B, Zhang Z, Yu J, Shen L, Luo Q, Ye J
International immunopharmacology 2023 May;118:110054
International immunopharmacology 2023 May;118:110054
Shengjiang Xiexin Decoction ameliorates antibiotic-associated diarrhea by altering the gut microbiota and intestinal metabolic homeostasis.
Zhang CE, Yu XH, Cui YT, Wang HJ, Chen X, Ma XJ, Li H, Su JR, Ma ZJ, Huang LQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154737
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154737
The protective effects of electroacupuncture on intestinal barrier lesions in IBS and UC model.
Liu S, Huang Q, Huang Q, Wang Y, Li S, Wang J, Wu Q
Scientific reports 2023 May 4;13(1):7276
Scientific reports 2023 May 4;13(1):7276
HCMV Infection Reduces Nidogen-1 Expression, Contributing to Impaired Neural Rosette Development in Brain Organoids.
Ijezie EC, O'Dowd JM, Kuan MI, Faeth AR, Fortunato EA
Journal of virology 2023 May 31;97(5):e0171822
Journal of virology 2023 May 31;97(5):e0171822
Gut Microbiota from Short-Chain Chlorinated Paraffin-Exposed Mice Promotes Astrocyte Activation by Disrupting the Intestinal Tight Junction via Zonulin Upregulation.
Zhao X, Zhang T, Zheng Y, Zhao Z, Ding W, Zhang Z, Zhang Z, Wang R, Jiao M, Liu L, Yu S, Wang X, Huang R, Wu Q
Journal of agricultural and food chemistry 2023 May 31;71(21):8192-8202
Journal of agricultural and food chemistry 2023 May 31;71(21):8192-8202
Baicalin Attenuates H(2)O(2)-Induced Oxidative Stress by Regulating the AMPK/Nrf2 Signaling Pathway in IPEC-J2 Cells.
Liang J, Zhou Y, Cheng X, Chen J, Cao H, Guo X, Zhang C, Zhuang Y, Hu G
International journal of molecular sciences 2023 May 29;24(11)
International journal of molecular sciences 2023 May 29;24(11)
Calcitriol, an Active Form of Vitamin D3, Mitigates Skin Barrier Dysfunction in Atopic Dermatitis NC/Nga Mice.
Umehara Y, Trujillo-Paez JV, Yue H, Peng G, Nguyen HLT, Okumura K, Ogawa H, Niyonsaba F
International journal of molecular sciences 2023 May 27;24(11)
International journal of molecular sciences 2023 May 27;24(11)
Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine.
Gong S, Zhu S, Zhou P, Cheng CY, Li W, Yao W, Sun F
ACS omega 2023 May 23;8(20):18245-18254
ACS omega 2023 May 23;8(20):18245-18254
Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions.
Zhou L, Lao Z, Fan X, Hao M, Yang Y
Bioscience, biotechnology, and biochemistry 2023 May 19;87(6):627-637
Bioscience, biotechnology, and biochemistry 2023 May 19;87(6):627-637
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zhang MF, Wan SC, Chen WB, Yang DH, Liu WQ, Li BL, Aierken A, Du XM, Li YX, Wu WP, Yang XC, Wei YD, Li N, Peng S, Li XL, Li GP, Hua JL
Zoological research 2023 May 18;44(3):505-521
Zoological research 2023 May 18;44(3):505-521
Therapeutic mechanisms of the medicine and food homology formula Xiao-Ke-Yin on glucolipid metabolic dysfunction revealed by transcriptomics, metabolomics and microbiomics in mice.
Li M, Cheng D, Peng C, Huang Y, Geng J, Huang G, Wang T, Xu A
Chinese medicine 2023 May 18;18(1):57
Chinese medicine 2023 May 18;18(1):57
Hydrogen inhalation ameliorates hepatic inflammation and modulates gut microbiota in rats with high-fat diet-induced non-alcoholic fatty liver disease.
Xue J, Zhao M, Liu Y, Jia X, Zhang X, Gu Q, Xie Y, Qin S, Liu B
European journal of pharmacology 2023 May 15;947:175698
European journal of pharmacology 2023 May 15;947:175698
Bazedoxifene attenuates intestinal injury in sepsis by suppressing the NF-κB/NLRP3 signaling pathways.
Zhang X, Ning W, Gao G, Zhou Y, Duan XB, Li X, Li D, Guo R
European journal of pharmacology 2023 May 15;947:175681
European journal of pharmacology 2023 May 15;947:175681
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Zhao X, He X, Wei W, Huang K
European journal of pharmacology 2023 May 15;947:175671
European journal of pharmacology 2023 May 15;947:175671
HC067047 Ameliorates Sepsis-associated Encephalopathy by Suppressing Endoplasmic Reticulum Stress and Oxidative Stress-Induced Pyroptosis in the Hippocampi of Mice.
Zhong X, Wang Y, Liu D, Liang Y, Liu W, Huang Y, Xie L, Cao W, Xu Y, Chen L
Neuroscience 2023 May 1;517:117-127
Neuroscience 2023 May 1;517:117-127
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Zhang Z, Cheng J, Yang L, Li X, Hua R, Xu D, Jiang Z, Li Q
Free radical biology & medicine 2023 May 1;200:26-35
Free radical biology & medicine 2023 May 1;200:26-35
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
Hu P, Zong B, Chen Q, Shao R, Chen M, Yang Y, Shao G
Heliyon 2023 Mar;9(3):e14309
Heliyon 2023 Mar;9(3):e14309
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
Yao F, Luo Y, Chen Y, Li Y, Hu X, You X, Li Z, Yu S, Tian D, Zheng M, Cheng L, Jing J
Cellular and molecular neurobiology 2023 Mar;43(2):741-756
Cellular and molecular neurobiology 2023 Mar;43(2):741-756
Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
Kawaguchi S, Sakuraba H, Kikuchi H, Matsuki K, Hayashi Y, Ding J, Tanaka Y, Seya K, Matsumiya T, Hiraga H, Fukuda S, Sasaki K, Imaizumi T
Experimental and therapeutic medicine 2023 Mar;25(3):112
Experimental and therapeutic medicine 2023 Mar;25(3):112
A novel model of subretinal edema induced by DL-alpha aminoadipic acid.
Xie Z, Wu X, Cheng R, Huang J, Wang X, Shi Q, Xu B, Paulus YM, Yuan S, Liu Q
Experimental eye research 2023 Mar;228:109388
Experimental eye research 2023 Mar;228:109388
The Polo-Like Kinase 1-Mammalian Target of Rapamycin Axis Regulates Autophagy to Prevent Intestinal Barrier Dysfunction During Sepsis.
Cao YY, Qiao Y, Wang ZH, Chen Q, Qi YP, Lu ZM, Wang Z, Lu WH
The American journal of pathology 2023 Mar;193(3):296-312
The American journal of pathology 2023 Mar;193(3):296-312
S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung.
Hao M, Fu R, Tai J, Tian Z, Yuan X, Chen Y, Wang M, Jiang H, Ji M, Lai F, Xue N, Bai L, Zhu Y, Lv X, Chen X, Jin J
Acta pharmaceutica Sinica. B 2023 Mar;13(3):1110-1127
Acta pharmaceutica Sinica. B 2023 Mar;13(3):1110-1127
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
Wang P, Li T, Niu C, Sun S, Liu D
International immunopharmacology 2023 Mar;116:109763
International immunopharmacology 2023 Mar;116:109763
Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation.
Ning W, Gao G, Zhou Y, Li WQ, Yang HH, Duan XB, Li X, Gong YB, Li D, Guo R
International immunopharmacology 2023 Mar;116:109747
International immunopharmacology 2023 Mar;116:109747
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Chen L, Mao M, Liu D, Liu W, Wang Y, Xie L, Deng Y, Lin Y, Xu Y, Zhong X, Cao W
International immunopharmacology 2023 Mar;116:109648
International immunopharmacology 2023 Mar;116:109648
Cimifugin suppresses type 2 airway inflammation by binding to SPR and regulating its protein expression in a non-enzymatic manner.
Gu X, Chen Y, Qian P, He T, Wu Y, Lin W, Zheng J, Hong M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154657
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154657
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Zhao S, Hu S, Sun K, Luo L, Zeng L
Food & function 2023 Mar 6;14(5):2313-2325
Food & function 2023 Mar 6;14(5):2313-2325
Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis.
Zhang ML, Wang M, Chen J, Liu YJ, Yu YJ, Liu LM, Zheng XH, Xiao YC, Zhang JM, Zhu MX, Yue X, Zhao Y, Niu W, Li ZC
European journal of pharmacology 2023 Mar 5;942:175545
European journal of pharmacology 2023 Mar 5;942:175545
p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.
Gao J, Li A, Fujii S, Huang F, Nakatomi C, Nakamura I, Honda H, Kiyoshima T, Jimi E
Scientific reports 2023 Mar 29;13(1):5144
Scientific reports 2023 Mar 29;13(1):5144
Integration of metabolomics and transcriptomics to reveal ferroptosis is involved in Tripterygium wilfordii polyglycoside tablet-induced testicular injury.
Qin Z, Zhang G, Jiang S, Ning F, Zhao Z, Huang M, Jin J
Journal of ethnopharmacology 2023 Mar 25;304:116055
Journal of ethnopharmacology 2023 Mar 25;304:116055
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Wei R, Su Z, Mackenzie GG
Food & function 2023 Mar 20;14(6):2684-2697
Food & function 2023 Mar 20;14(6):2684-2697
Alteration of gut microbiome and metabolome by Clostridium butyricum can repair the intestinal dysbiosis caused by antibiotics in mice.
Liu X, Qiu X, Yang Y, Wang J, Wang Q, Liu J, Yang F, Liu Z, Qi R
iScience 2023 Mar 17;26(3):106190
iScience 2023 Mar 17;26(3):106190
Emblica officinalis mitigates intestinal toxicity of mice by modulating gut microbiota in lead exposure.
Wang Y, Zhou H, Che Y, Wan X, Ding X, Zheng S, Wu C, Qin M, Xu Y, Yu Y, Kulyar MF, Li K, Wu Y
Ecotoxicology and environmental safety 2023 Mar 15;253:114648
Ecotoxicology and environmental safety 2023 Mar 15;253:114648
Highly stable fibronectin-mimetic-peptide-based supramolecular hydrogel to accelerate corneal wound healing.
Hu Y, Shi H, Ma X, Xia T, Wu Y, Chen L, Ren Z, Lei L, Jiang J, Wang J, Li X
Acta biomaterialia 2023 Mar 15;159:128-139
Acta biomaterialia 2023 Mar 15;159:128-139
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression.
Yang F, Li L, Zhou Y, Pan W, Liang X, Huang L, Huang J, Cheng Y, Geng L, Xu W, Gong S
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):516-526
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):516-526
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Wang Y, Zhang L, Lv L, Zhou Z, Xi H
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Circulating exosomal miR-155-5p contributes to severe acute pancreatitis-associated intestinal barrier injury by targeting SOCS1 to activate NLRP3 inflammasome-mediated pyroptosis.
Shao Y, Li Y, Jiang Y, Li H, Wang J, Zhang D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jun;37(6):e23003
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jun;37(6):e23003
Tongqiao Huoxue Decoction ameliorates traumatic brain injury-induced gastrointestinal dysfunction by regulating CD36/15-LO/NR4A1 signaling, which fails when CD36 and CX3CR1 are deficient.
Wei C, Zhu F, Yu J, Gao F, Yuan Y, Zhang Y, Liu X, Chu S, Cui D, Fan H, Wang W
CNS neuroscience & therapeutics 2023 Jun;29 Suppl 1(Suppl 1):161-184
CNS neuroscience & therapeutics 2023 Jun;29 Suppl 1(Suppl 1):161-184
SRT1720 attenuates UVA-induced corneal endothelial damage via inhibition of oxidative stress and cellular apoptosis.
Dong C, Li Z, Wang X, Zou D, Duan H, Zhao C, Zhou Q, Shi W
Experimental eye research 2023 Jun;231:109464
Experimental eye research 2023 Jun;231:109464
Dopamine D1 receptor agonist alleviates acute lung injury via modulating inflammatory responses in macrophages and barrier function in airway epithelial cells.
Meng L, Wang M, Gao Y, Chen L, Wang K, Gao W, Liu Q
Free radical biology & medicine 2023 Jun;202:2-16
Free radical biology & medicine 2023 Jun;202:2-16
Spermidine protects intestinal mucosal barrier function in mice colitis via the AhR/Nrf2 and AhR/STAT3 signaling pathways.
Yan B, Mao X, Hu S, Wang S, Liu X, Sun J
International immunopharmacology 2023 Jun;119:110166
International immunopharmacology 2023 Jun;119:110166
YES-associated protein-regulated Smad7 worsen epithelial barrier injury of chronic sinusitis with nasal polyps.
Jiang X, Shu L, Liu Y, Shen Y, Ke X, Liu J, Yang Y
Immunity, inflammation and disease 2023 Jun;11(6):e907
Immunity, inflammation and disease 2023 Jun;11(6):e907
Systematic assessment of hexavalent chromium-induced damage to male fertility and the preventive role of melatonin: a longitudinal study from the translational point of view.
Li T, Lv Y, Wu Z, Guo M, Liu R, Zeng W, Zheng Y
Molecular human reproduction 2023 Jun 30;29(7)
Molecular human reproduction 2023 Jun 30;29(7)
Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice.
Liu C, Zhou Y, Gao H, Zhang Z, Zhou Y, Xu Z, Zhang C, Xu Z, Zheng H, Ma YQ
Thrombosis journal 2023 Jun 29;21(1):71
Thrombosis journal 2023 Jun 29;21(1):71
Non-Invasive and Label-Free On-Chip Impedance Monitoring of Heatstroke.
Zhao Y, Fan W, Liu A, Pan S, Xu C, Peng H, Yin B, Wang X, Dong J, Pan Z
Biosensors 2023 Jun 27;13(7)
Biosensors 2023 Jun 27;13(7)
Fecal microbiota transplantation from sodium alginate-dosed mice and normal mice mitigates intestinal barrier injury and gut dysbiosis induced by antibiotics and cyclophosphamide.
Huang J, Zhou H, Song T, Wang B, Ge H, Zhang D, Shen P, Qiu X, Li H
Food & function 2023 Jun 19;14(12):5690-5701
Food & function 2023 Jun 19;14(12):5690-5701
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice.
Wu H, Wu Z, Qiu Y, Zhao F, Liao M, Zhong Z, Chen J, Zeng Y, Liu R
iScience 2023 Jun 16;26(6):106979
iScience 2023 Jun 16;26(6):106979
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
Qiao N, An Z, Fu Z, Chen X, Tong Q, Zhang Y, Ren H
European journal of pharmacology 2023 Jun 15;949:175717
European journal of pharmacology 2023 Jun 15;949:175717
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Liu J, Fu L, Yin F, Yin L, Song X, Guo H, Liu J
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
Polystyrene microplastics aggravate acute pancreatitis in mice.
Zheng J, Tan Z, Wu J, Liu J, Yang T, Yang H
Toxicology 2023 Jun 1;491:153513
Toxicology 2023 Jun 1;491:153513
MiR-26a-5p from HucMSC-derived extracellular vesicles inhibits epithelial mesenchymal transition by targeting Adam17 in silica-induced lung fibrosis.
Zhao J, Jiang Q, Xu C, Jia Q, Wang H, Xue W, Wang Y, Zhu Z, Tian L
Ecotoxicology and environmental safety 2023 Jun 1;257:114950
Ecotoxicology and environmental safety 2023 Jun 1;257:114950
Fluoride disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated RhoA/ROCK signaling and myosin light chain kinase.
Li L, Xin J, Wang H, Wang Y, Peng W, Sun N, Huang H, Zhou Y, Liu X, Lin Y, Fang J, Jing B, Pan K, Zeng Y, Zeng D, Qin X, Bai Y, Ni X
Ecotoxicology and environmental safety 2023 Jun 1;257:114940
Ecotoxicology and environmental safety 2023 Jun 1;257:114940
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Li X, Wang W, Hou Y, Li G, Yi H, Cui S, Zhang J, He X, Zhao H, Yang Z, Qiu Y, Liu Z, Xie J
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Huang Y, Liu J, He J, Tan F, Lu M, Yuan F, Zhu X, Kong L
Heliyon 2023 Jul;9(7):e17874
Heliyon 2023 Jul;9(7):e17874
Effect of lonidamine derivatives on the inhibition of transformed cell area expansion.
Aoyama M, Homma T, Koharazawa R, Suhara Y, Semba K
Biochemistry and biophysics reports 2023 Jul;34:101480
Biochemistry and biophysics reports 2023 Jul;34:101480
Thioredoxin1 is a target to attenuate diabetes‑induced RPE cell dysfunction in human ARPE19 cells by alleviating oxidative stress.
Qi H, Liu T, Liu J, Teng Q, Ma Z, Wang S, Wen S, Zhang C, Ren X, Kong H, Kong L
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
Zhang RB, Dong LC, Huang Q, Shen Y, Li HY, Yu SG, Wu QF
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
Protective effects of melatonin on deoxynivalenol-induced oxidative stress and autophagy in IPEC-J2 cells.
Xu Y, Xie Y, Wu Z, Wang H, Chen Z, Wang J, Bao W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113803
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113803
Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases.
Guo HH, Shen HR, Wang LL, Luo ZG, Zhang JL, Zhang HJ, Gao TL, Han YX, Jiang JD
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114754
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114754
The ACE2 activator diminazene aceturate ameliorates colitis by repairing the gut-vascular barrier in mice.
Zhang C, Cao X, Wang H, Li Z, Zhang Y
Microvascular research 2023 Jul;148:104544
Microvascular research 2023 Jul;148:104544
Programmed cell death 10 increased blood-brain barrier permeability through HMGB1/TLR4 mediated downregulation of endothelial ZO-1 in glioblastoma.
Wu S, Wang J, Liu J, Zhu H, Li R, Wan X, Lei J, Li Y, You C, Hu F, Zhang S, Zhao K, Shu K, Lei T
Cellular signalling 2023 Jul;107:110683
Cellular signalling 2023 Jul;107:110683
Effects of the polypeptide from peanut meal mixed fermentation on lipid metabolism and intestinal flora of hyperlipidemic mice.
Ding H, Zhang H, Lu Y, Jiang X, Liu Q, Hu Y, Sun H, Ma A
Journal of the science of food and agriculture 2023 Jul;103(9):4351-4359
Journal of the science of food and agriculture 2023 Jul;103(9):4351-4359
DSPE-PEG polymer enhanced berberine absorption specifically in the small intestine of rats through paracellular passway.
Gao Y, Sun J, Wang S, Huxiao L, Xu Y, Zhang H
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):931-939
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):931-939
The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage.
Ghosh S, Erickson D, Chua MJ, Collins J, Jala VR
bioRxiv : the preprint server for biology 2023 Jul 24;
bioRxiv : the preprint server for biology 2023 Jul 24;
Mn(3)O(4) Nanozyme Loaded Thermosensitive PDLLA-PEG-PDLLA Hydrogels for the Treatment of Inflammatory Bowel Disease.
Yang Z, Zhou X, Wang L, Guo H, Han M, Guo H, Chen Y, Wu A, Li H, Chen S, Xie Y, Wang X
ACS applied materials & interfaces 2023 Jul 19;15(28):33273-33287
ACS applied materials & interfaces 2023 Jul 19;15(28):33273-33287
Alginate oligosaccharide structures differentially affect DSS-induced colitis in mice by modulating gut microbiota.
Lu S, Na K, Wei J, Tao T, Zhang L, Fang Y, Li X, Guo X
Carbohydrate polymers 2023 Jul 15;312:120806
Carbohydrate polymers 2023 Jul 15;312:120806
Open source board based acoustofluidic transwells for reversible disruption of the blood-brain barrier for therapeutic delivery.
Wang K, Sun C, Dumčius P, Zhang H, Liao H, Wu Z, Tian L, Peng W, Fu Y, Wei J, Cai M, Zhong Y, Li X, Yang X, Cui M
Biomaterials research 2023 Jul 15;27(1):69
Biomaterials research 2023 Jul 15;27(1):69
Mechanistic study for drug induced cholestasis using batch-fabricated 3D spheroids developed by agarose-stamping method.
Guo H, Yu H, Zu H, Cui J, Ding H, Xia Y, Chen D, Zeng Y, Wang Y, Wang Y, Zhang LW
Toxicology letters 2023 Jul 1;383:64-74
Toxicology letters 2023 Jul 1;383:64-74
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Chen W, Yu H, Sun C, Dong M, Zhao N, Wang Y, Yu K, Zhang J, Xu N, Liu W
Toxicology letters 2023 Jul 1;383:177-191
Toxicology letters 2023 Jul 1;383:177-191
Hexavalent chromium disrupts the skin barrier by targeting ROS-mediated mitochondrial pathway apoptosis in keratinocytes.
Wang C, Shang H, Zhang S, Wang X, Liu D, Shen M, Li N, Jiang Y, Wei K, Zhu R
Chemico-biological interactions 2023 Jul 1;379:110523
Chemico-biological interactions 2023 Jul 1;379:110523
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Wang CQ, Su Z, Dai CG, Song JL, Qian B
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation.
Lien WC, Zhou XR, Liang YJ, Ching CT, Wang CY, Lu FI, Chang HC, Lin FH, Wang HD
Bioengineering & translational medicine 2023 Jan;8(1):e10346
Bioengineering & translational medicine 2023 Jan;8(1):e10346
Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury.
Xie C, Wang Y, Wang J, Xu Y, Liu H, Guo J, Zhu L
Molecular neurobiology 2023 Jan;60(1):51-67
Molecular neurobiology 2023 Jan;60(1):51-67
Apelin-13 prevents the effects of oxygen-glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT-mTOR signaling.
Zhang R, Wu F, Cheng B, Wang C, Bai B, Chen J
Experimental biology and medicine (Maywood, N.J.) 2023 Jan;248(2):146-156
Experimental biology and medicine (Maywood, N.J.) 2023 Jan;248(2):146-156
Metasilicate-based alkaline mineral water confers diarrhea resistance in maternally separated piglets via the microbiota-gut interaction.
Chen J, Xu XW, Kang JX, Zhao BC, Xu YR, Li JL
Pharmacological research 2023 Jan;187:106580
Pharmacological research 2023 Jan;187:106580
Desulfovibrio desulfuricans aggravates atherosclerosis by enhancing intestinal permeability and endothelial TLR4/NF-κB pathway in Apoe (-/-) mice.
Zhang K, Qin X, Qiu J, Sun T, Qu K, Din AU, Yan W, Li T, Chen Y, Gu W, Rao X, Wang G
Genes & diseases 2023 Jan;10(1):239-253
Genes & diseases 2023 Jan;10(1):239-253
A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection.
Däullary T, Imdahl F, Dietrich O, Hepp L, Krammer T, Fey C, Neuhaus W, Metzger M, Vogel J, Westermann AJ, Saliba AE, Zdzieblo D
Gut microbes 2023 Jan-Dec;15(1):2186109
Gut microbes 2023 Jan-Dec;15(1):2186109
FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
Li B, Xi W, Bai Y, Liu X, Zhang Y, Li L, Bian L, Liu C, Tang Y, Shen L, Yang L, Gu X, Xie J, Zhou Z, Wang Y, Yu X, Wang J, Chao J, Han B, Yao H
Nature communications 2023 Jan 30;14(1):489
Nature communications 2023 Jan 30;14(1):489
Effects of 6-Shogaol on Glucose Uptake and Intestinal Barrier Integrity in Caco-2 Cells.
Jiao W, Sang Y, Wang X, Wang S
Foods (Basel, Switzerland) 2023 Jan 21;12(3)
Foods (Basel, Switzerland) 2023 Jan 21;12(3)
Gut Bacterial Indole-3-acetic Acid Induced Immune Promotion Mediates Preventive Effects of Fu Brick Tea Polyphenols on Experimental Colitis.
Zhang X, Shi L, Wang N, Li Q, Zhang L, Han N, Yan T, Ren D, Zhang B, Zhao Y, Yang X
Journal of agricultural and food chemistry 2023 Jan 18;71(2):1201-1213
Journal of agricultural and food chemistry 2023 Jan 18;71(2):1201-1213
Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions.
Adzraku SY, Wang G, Cao C, Bao Y, Wang Y, Smith AO, Du Y, Wang H, Li Y, Xu K, Qiao J, Ju W, Zeng L
Cellular & molecular biology letters 2023 Jan 16;28(1):2
Cellular & molecular biology letters 2023 Jan 16;28(1):2
Intestinal epithelium penetration of liraglutide via cholic acid pre-complexation and zein/rhamnolipids nanocomposite delivery.
Bao X, Qian K, Xu M, Chen Y, Wang H, Pan T, Wang Z, Yao P, Lin L
Journal of nanobiotechnology 2023 Jan 16;21(1):16
Journal of nanobiotechnology 2023 Jan 16;21(1):16
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
Yang Z, Wang YX, Wen JK, Gao HT, Han ZW, Qi JC, Gu JF, Zhao CM, Zhang H, Shi B, Wang DD, Wang XL, Qu CB
Cell death & disease 2023 Jan 13;14(1):26
Cell death & disease 2023 Jan 13;14(1):26
β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota.
Zhang X, Zhang Y, He Y, Zhu X, Ai Q, Shi Y
Journal of translational medicine 2023 Jan 10;21(1):14
Journal of translational medicine 2023 Jan 10;21(1):14
Involvement of gut-brain communication in arsenite-induced neurobehavioral impairments in adult male mice.
Lu Z, Wang F, Xia Y, Cheng S, Zhang J, Qin X, Tian X, Wang B, Qiu J, Zou Z, Jiang X, Chen C
Ecotoxicology and environmental safety 2023 Jan 1;249:114370
Ecotoxicology and environmental safety 2023 Jan 1;249:114370
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Wang J, Xu J, Dong Y, Su Z, Su H, Cheng Q, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
Effects of Buyang Huanwu Decoction on Intestinal Barrier, Intestinal Flora, and Trimethylamine Oxide in Rats with Heart Failure.
Weng JQ, Li JB, Yuan MF, Yao TT, Zhang JF, Zeng YY, Zhao J, Li Y, Xu K, Shen XX
Chinese journal of integrative medicine 2023 Feb;29(2):155-161
Chinese journal of integrative medicine 2023 Feb;29(2):155-161
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Li B, Li W, Zheng M, Wang Y, Diao Y, Mou X, Liu J
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses.
Scheibner D, Salaheldin AH, Bagato O, Zaeck LM, Mostafa A, Blohm U, Müller C, Eweas AF, Franzke K, Karger A, Schäfer A, Gischke M, Hoffmann D, Lerolle S, Li X, Abd El-Hamid HS, Veits J, Breithaupt A, Boons GJ, Matrosovich M, Finke S, Pleschka S, Mettenleiter TC, de Vries RP, Abdelwhab EM
PLoS pathogens 2023 Feb;19(2):e1011135
PLoS pathogens 2023 Feb;19(2):e1011135
Capsaicin shapes gut microbiota and pre-metastatic niche to facilitate cancer metastasis to liver.
Cheng P, Wu J, Zong G, Wang F, Deng R, Tao R, Qian C, Shan Y, Wang A, Zhao Y, Wei Z, Lu Y
Pharmacological research 2023 Feb;188:106643
Pharmacological research 2023 Feb;188:106643
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
Wu F, Wang P, Wei X, Yang Y, Al Mamun A, Zhang X, Zhu Y, Mo T, Zhang H, Jiang C, Hu J, Xiao J
Materials today. Bio 2023 Feb;18:100546
Materials today. Bio 2023 Feb;18:100546
PLK1 protects intestinal barrier function in sepsis: A translational research.
Cao YY, Li J, Chen Q, Qi YP, Xu QC, He JM, Wang Z, Lu WH
Cytokine 2023 Feb;162:156113
Cytokine 2023 Feb;162:156113
DHA-enriched phosphatidylserine alleviates high fat diet-induced jejunum injury in mice by modulating gut microbiota.
Tian S, Zhao Y, Qian L, Jiang S, Tang Y, Han T
Food & function 2023 Feb 6;14(3):1415-1429
Food & function 2023 Feb 6;14(3):1415-1429
Lutein Prevents Liver Injury and Intestinal Barrier Dysfunction in Rats Subjected to Chronic Alcohol Intake.
Zhao S, Zhang Y, Ding H, Hu S, Wu X, Ma A, Ma Y
Nutrients 2023 Feb 28;15(5)
Nutrients 2023 Feb 28;15(5)
Fecal microbiota transplantation attenuates Escherichia coli infected outgrowth by modulating the intestinal microbiome.
Wang Y, He Y, Liang Y, Liu H, Chen X, Kulyar MF, Shahzad A, Wei K, Li K
Microbial cell factories 2023 Feb 17;22(1):30
Microbial cell factories 2023 Feb 17;22(1):30
Small molecule compound K-7174 attenuates neuropsychiatric manifestations in lupus-prone mice.
Fan Y, Liu X, Wu J, Ni J, Liang J, Hou Y, Dou H
Brain research 2023 Feb 15;1801:148203
Brain research 2023 Feb 15;1801:148203
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Guo TT, Zhang Z, Sun Y, Zhu RY, Wang FX, Ma LJ, Jiang L, Liu HD
Nutrients 2023 Feb 13;15(4)
Nutrients 2023 Feb 13;15(4)
Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.
Wang X, Huang S, Zhang M, Su Y, Pan Z, Liang J, Xie X, Wang Q, Chen J, Zhou L, Luo X
Journal of ethnopharmacology 2023 Feb 10;302(Pt B):115919
Journal of ethnopharmacology 2023 Feb 10;302(Pt B):115919
Effects of Houpo Mahuang Decoction on serum metabolism and TRPV1/Ca(2+)/TJs in asthma.
Zhou L, Hao M, Fan X, Lao Z, Li M, Shang E
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115873
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115873
Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE-19 Cells.
Ren C, Zhou P, Zhang M, Yu Z, Zhang X, Tombran-Tink J, Barnstable CJ, Li X
International journal of molecular sciences 2023 Feb 10;24(4)
International journal of molecular sciences 2023 Feb 10;24(4)
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
Lin D, Sun Q, Liu Z, Pan J, Zhu J, Wang S, Jia S, Zheng M, Li X, Gong F
Free radical biology & medicine 2023 Feb 1;195:199-218
Free radical biology & medicine 2023 Feb 1;195:199-218
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Gao J, Wang Y, Jia Z, Xue J, Zhou T, Zu G
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Toxicity assessment of organophosphate flame retardant triphenyl phosphate (TPHP) on intestines in mice.
Peng C, Zhang X, Chen Y, Wang L
Ecotoxicology and environmental safety 2023 Dec;268:115685
Ecotoxicology and environmental safety 2023 Dec;268:115685
Increased R-spondin 3 contributes to aerobic exercise-induced protection against renal vascular endothelial hyperpermeability and acute kidney injury.
Xu QF, Zhang H, Zhao Y, Liu D, Wei J, Jiang L, Liu YJ, Zhu XY
Acta physiologica (Oxford, England) 2023 Dec;239(4):e14036
Acta physiologica (Oxford, England) 2023 Dec;239(4):e14036
Deciphering the interplay between LPS/TLR4 pathways, neurotransmitter, and deltamethrin-induced depressive-like behavior: Perspectives from the gut-brain axis.
Li T, Chen H, Xu B, Yu M, Li J, Shi Y, Xia S, Wu S
Pesticide biochemistry and physiology 2023 Dec;197:105697
Pesticide biochemistry and physiology 2023 Dec;197:105697
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Li J, Bai J, Song Z, Ji Y, Chen Z, Yang Y, Wu Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
Wen W, Xu Y, Qian W, Huang L, Gong J, Li Y, Zhu W, Guo Z
Gut microbes 2023 Dec;15(2):2265578
Gut microbes 2023 Dec;15(2):2265578
The E3 ubiquitin ligase RNF31 mediates the development of ulcerative colitis by regulating NLRP3 inflammasome activation.
Wang P, Tang CT, Li J, Huang X, Jin R, Yin F, Liu Z, Chen Y, Zeng C
International immunopharmacology 2023 Dec;125(Pt B):111194
International immunopharmacology 2023 Dec;125(Pt B):111194
Ursodeoxycholic acid alleviates sepsis-induced lung injury by blocking PANoptosis via STING pathway.
He YQ, Deng JL, Zhou CC, Jiang SG, Zhang F, Tao X, Chen WS
International immunopharmacology 2023 Dec;125(Pt B):111161
International immunopharmacology 2023 Dec;125(Pt B):111161
Combined VEGF and bFGF loaded nanofiber membrane protects against neuronal injury and hypomyelination in a rat model of chronic cerebral hypoperfusion.
Wu YF, Sun J, Chen M, Lin Q, Jin KY, Su SH, Hai J
International immunopharmacology 2023 Dec;125(Pt A):111108
International immunopharmacology 2023 Dec;125(Pt A):111108
Protective effect of ethyl ferulate against hypoxic injury in retinal cells and retinal neovascularization in an oxygen-induced retinopathy model.
Xue R, Fan XL, Yang Q, Yu C, Lu TY, Wan GM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155097
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155097
Dual-Targeted Nanoparticle-in-Microparticle System for Ulcerative Colitis Therapy.
Zhang Y, Wu Y, Yan Y, Ma Y, Tu L, Shao J, Tang X, Chen L, Liang G, Yin L
Advanced healthcare materials 2023 Dec;12(31):e2301518
Advanced healthcare materials 2023 Dec;12(31):e2301518
Effects of enteral nutrition supplemented with octanoic acid on lipopolysaccharide-induced intestinal injury: role of peroxisome proliferator-activated receptor γ/STAT-1/myeloid differentiation factor 88 pathway.
Tang J, Li X, Li W, Cao C
Nutrition (Burbank, Los Angeles County, Calif.) 2023 Dec;116:112216
Nutrition (Burbank, Los Angeles County, Calif.) 2023 Dec;116:112216
Plasma-Activated Solutions Mitigates DSS-Induced Colitis via Restoring Redox Homeostasis and Reversing Microbiota Dysbiosis.
Sun T, Ren K, Xu G, Ma R, Wang X, Min T, Xie X, Sun A, Ma Y, Wang H, Zhang Y, Zhu K, Dang C, Zhang G, Zhang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304044
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304044
IGF2/IGF2R/Sting signaling as a therapeutic target in DSS-induced ulcerative colitis.
Chen L, Zhong XL, Cao WY, Mao ML, Liu DD, Liu WJ, Zu XY, Liu JH
European journal of pharmacology 2023 Dec 5;960:176122
European journal of pharmacology 2023 Dec 5;960:176122
FGF21 alleviates endothelial mitochondrial damage and prevents BBB from disruption after intracranial hemorrhage through a mechanism involving SIRT6.
Wang R, Wang J, Zhang Z, Ma B, Sun S, Gao L, Gao G
Molecular medicine (Cambridge, Mass.) 2023 Dec 4;29(1):165
Molecular medicine (Cambridge, Mass.) 2023 Dec 4;29(1):165
Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells.
He W, Wang J, Han M, Wang L, Li L, Zhang J, Chen S, Guo J, Zhai X, Yang J
Toxins 2023 Dec 4;15(12)
Toxins 2023 Dec 4;15(12)
Bacterial butyrate mediates the anti-atherosclerotic effect of silybin.
Shen HR, Wang ZY, Shen Z, Liu TT, Guo YD, Gao TL, Guo HH, Han YX, Jiang JD
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115916
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115916
Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis and Ameliorates Colitis.
Jean Wilson E, Sirpu Natesh N, Ghadermazi P, Pothuraju R, Prajapati DR, Pandey S, Kaifi JT, Dodam JR, Bryan JN, Lorson CL, Watrelot AA, Foster JM, Mansell TJ, Joshua Chan SH, Batra SK, Subbiah J, Rachagani S
International journal of molecular sciences 2023 Dec 30;25(1)
International journal of molecular sciences 2023 Dec 30;25(1)
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
Shi L, Wang Z, Rong J, Fei X, Li X, He B, Gong W, Qian J
Aging 2023 Dec 27;15(24):15183-15195
Aging 2023 Dec 27;15(24):15183-15195
p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP.
Ouyang H, Wu S, Li W, Grey MJ, Wu W, Hansen SH
Cell reports 2023 Dec 26;42(12):113486
Cell reports 2023 Dec 26;42(12):113486
Clostridium butyricum and Clostridium tyrobutyricum: angel or devil for necrotizing enterocolitis?
Tao R, Zong G, Pan Y, Li H, Cheng P, Deng R, Chen W, Wang A, Xia S, Tang W, Lu Y, Wei Z
mSystems 2023 Dec 21;8(6):e0073223
mSystems 2023 Dec 21;8(6):e0073223
Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients.
Palenca I, Seguella L, Zilli A, Basili Franzin S, Del Re A, Pepi F, Troiani A, Pesce M, Rurgo S, De Palma FDE, Luglio G, Tropeano FP, Sarnelli G, Esposito G
International journal of molecular sciences 2023 Dec 21;25(1)
International journal of molecular sciences 2023 Dec 21;25(1)
Gut microbiota-associated taurine metabolism dysregulation in a mouse model of Parkinson's disease.
Cui C, Song H, Han Y, Yu H, Li H, Yang Y, Zhang B
mSphere 2023 Dec 20;8(6):e0043123
mSphere 2023 Dec 20;8(6):e0043123
Beta-Amyloid Enhances Vessel Formation in Organotypic Brain Slices Connected to Microcontact Prints.
Steiner K, Humpel C
Biomolecules 2023 Dec 19;14(1)
Biomolecules 2023 Dec 19;14(1)
Heat Stress-Induced Fetal Intrauterine Growth Restriction Is Associated with Elevated LPS Levels Along the Maternal Intestine-Placenta-Fetus Axis in Pregnant Mice.
Zheng X, Ma W, Wang Y, Wu C, Wang J, Ma Z, Wei Y, Cui C, Zhang S, Guan W, Chen F
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19592-19609
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19592-19609
2'-Fucosyllactose alleviates OVA-induced food allergy in mice by ameliorating intestinal microecology and regulating the imbalance of Th2/Th1 proportion.
Kou R, Wang J, Li A, Wang Y, Fan D, Zhang B, Fu W, Liu J, Fu H, Wang S
Food & function 2023 Dec 11;14(24):10924-10940
Food & function 2023 Dec 11;14(24):10924-10940
The role of ROS-pyroptosis in PM(2.5) induced air-blood barrier destruction.
Wei M, Cong Y, Lei J, Du R, Yang M, Lu X, Jiang Y, Cao R, Meng X, Jiang Z, Song L
Chemico-biological interactions 2023 Dec 1;386:110782
Chemico-biological interactions 2023 Dec 1;386:110782
Maternal Selenium-Enriched Yeast Supplementation in Sows Enhances Offspring Growth and Antioxidant Status through the Nrf2/Keap1 Pathway.
Xiong L, Lin T, Yue X, Zhang S, Liu X, Chen F, Zhang S, Guan W
Antioxidants (Basel, Switzerland) 2023 Dec 1;12(12)
Antioxidants (Basel, Switzerland) 2023 Dec 1;12(12)
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
Zhang ZT, Deng SM, Chen C, He QH, Peng XW, Liang QF, Zhuang GD, Wang SM, Tang D
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function.
Xia J, Li J, Deng M, Yin F, Liu J, Wang J
Inflammopharmacology 2023 Aug;31(4):2037-2047
Inflammopharmacology 2023 Aug;31(4):2037-2047
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Ge X, Wen H, Fei Y, Xue R, Cheng Z, Li Y, Cai K, Li L, Li M, Luo Z
Biomaterials 2023 Aug;299:122184
Biomaterials 2023 Aug;299:122184
Succinate signaling attenuates high-fat diet-induced metabolic disturbance and intestinal barrier dysfunction.
Li X, Huang G, Zhang Y, Ren Y, Zhang R, Zhu W, Yu K
Pharmacological research 2023 Aug;194:106865
Pharmacological research 2023 Aug;194:106865
Limosilactobacillus fermentum NCU003089 and Lactiplantibacillus plantarum NCU001261, two probiotics with inhibition of Escherichia coli and Cronobacter sakazakii translocation in vitro.
Wei B, Peng Z, Xiao M, Huang T, Zheng W, Xie M, Xiong T
Microbial pathogenesis 2023 Aug;181:106216
Microbial pathogenesis 2023 Aug;181:106216
Sphingosine 1-phosphate receptor 1 regulates blood-brain barrier permeability in epileptic mice.
Yang LX, Yao YY, Yang JR, Cheng HL, Zhu XJ, Zhang ZJ
Neural regeneration research 2023 Aug;18(8):1763-1769
Neural regeneration research 2023 Aug;18(8):1763-1769
Triclocarban exposure aggravates dextran sulfate sodium-induced colitis by deteriorating the gut barrier function and microbial community in mice.
Qin M, Lei H, Song Y, Wu M, Chen C, Cao Z, Zhang C, Du R, Zhang C, Wang X, Zhang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Aug;178:113908
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Aug;178:113908
MiR-874-5p targets VDR/NLRP3 to reduce intestinal pyroptosis and improve intestinal barrier damage in sepsis.
Shang L, Li J, Zhou F, Zhang M, Wang S, Yang S
International immunopharmacology 2023 Aug;121:110424
International immunopharmacology 2023 Aug;121:110424
Extracellular ATP accelerates cell death and decreases tight junction protein ZO-1 in hypoxic cochlear strial marginal cells in neonatal rats.
Zhao Y, Huang S, Xie R, Liu J
Cellular signalling 2023 Aug;108:110732
Cellular signalling 2023 Aug;108:110732
Arula-7 powder improves diarrhea and intestinal epithelial tight junction function associated with its regulation of intestinal flora in calves infected with pathogenic Escherichia coli O(1).
Chen H, Jia Z, He M, Chen A, Zhang X, Xu J, Wang C
Microbiome 2023 Aug 5;11(1):172
Microbiome 2023 Aug 5;11(1):172
Mechanisms of Lung and Intestinal Microbiota and Innate Immune Changes Caused by Pathogenic Enterococcus Faecalis Promoting the Development of Pediatric Pneumonia.
Tian Z, Deng T, Gui X, Wang L, Yan Q, Wang L
Microorganisms 2023 Aug 31;11(9)
Microorganisms 2023 Aug 31;11(9)
Zinc-Rutin Particles Ameliorate DSS-Induced Acute and Chronic Colitis via Anti-inflammatory and Antioxidant Protection of the Intestinal Epithelial Barrier.
Wu W, Liu L, Zhu Y, Ni J, Lu J, Wang X, Ma L, Jiang Y
Journal of agricultural and food chemistry 2023 Aug 30;71(34):12715-12729
Journal of agricultural and food chemistry 2023 Aug 30;71(34):12715-12729
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids.
Wang X, Quan J, Xiu C, Wang J, Zhang J
Chinese medicine 2023 Aug 30;18(1):110
Chinese medicine 2023 Aug 30;18(1):110
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis.
Jean Wilson E, Sirpu Natesh N, Ghadermazi P, Pothuraju R, Shanmugam M, Prajapati DR, Pandey S, Kaifi JT, Dodam JR, Bryan J, Lorson CL, Watrelot AA, Foster JM, Mansel TJ, Joshua Chan SH, Batra SK, Subbiah J, Rachagani S
bioRxiv : the preprint server for biology 2023 Aug 24;
bioRxiv : the preprint server for biology 2023 Aug 24;
Dextran sulfate sodium-induced mild chronic colitis induced cognitive impairment accompanied by inhibition of neuronal maturation in adolescent mice.
Lee K, Kumazoe M, Marugame Y, Fujimura Y, Tachibana H
Biochemical and biophysical research communications 2023 Aug 20;669:46-53
Biochemical and biophysical research communications 2023 Aug 20;669:46-53
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Ji L, Zhang L, Liang Z, Zhong S, Liu X, Liu Z, Poon WS, Song Y, Chen B, Wang R
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition.
Ma H, Zhang X, Liu L, Huang Y, Sun S, Chen K, Xin Q, Liu P, Yan Y, Wang Y, Li Y, Liu H, Zhao R, Tan K, Chen X, Yuan X, Li Y, Liu Y, Dai H, Liu C, Wang H, Zhang XD
Science advances 2023 Aug 2;9(31):eadh7828
Science advances 2023 Aug 2;9(31):eadh7828
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
Hu J, Ding R, Liu S, Wang J, Li J, Shang Y
iScience 2023 Aug 18;26(8):107503
iScience 2023 Aug 18;26(8):107503
Mechanisms of Qingyi Decoction in Severe Acute Pancreatitis-Associated Acute Lung Injury via Gut Microbiota: Targeting the Short-Chain Fatty Acids-Mediated AMPK/NF-κB/NLRP3 Pathway.
Wang Z, Liu J, Li F, Ma S, Zhao L, Ge P, Wen H, Zhang Y, Liu X, Luo Y, Yao J, Zhang G, Chen H
Microbiology spectrum 2023 Aug 17;11(4):e0366422
Microbiology spectrum 2023 Aug 17;11(4):e0366422
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Wang Z, Tan C, Duan C, Wu J, Zhou D, Hou L, Qian W, Han C, Hou X
Redox biology 2023 Apr;60:102618
Redox biology 2023 Apr;60:102618
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice.
Wang S, Liu J, Cheng D, Ren L, Zheng L, Chen F, Zeng T
Toxicology 2023 Apr;488:153487
Toxicology 2023 Apr;488:153487
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Xie Z, Wu XJ, Cheng RW, Cui JH, Yuan ST, Zhou JW, Liu QH
Acta pharmacologica Sinica 2023 Apr;44(4):897-912
Acta pharmacologica Sinica 2023 Apr;44(4):897-912
A mesoporous polydopamine-derived nanomedicine for targeted and synergistic treatment of inflammatory bowel disease by pH-Responsive drug release and ROS scavenging.
Guan H, Xu Z, Du G, Liu Q, Tan Q, Chen Y, Chen S, Wu J, Wang F, Zhang J, Sun L, Xiao W
Materials today. Bio 2023 Apr;19:100610
Materials today. Bio 2023 Apr;19:100610
Intranasal Delivery of Gene-Edited Microglial Exosomes Improves Neurological Outcomes after Intracerebral Hemorrhage by Regulating Neuroinflammation.
Guo M, Ge X, Wang C, Yin Z, Jia Z, Hu T, Li M, Wang D, Han Z, Wang L, Xiong X, Chen F, Lei P
Brain sciences 2023 Apr 8;13(4)
Brain sciences 2023 Apr 8;13(4)
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Xie Z, Zhang G, Liu R, Wang Y, Tsapieva AN, Zhang L, Han J
Nutrients 2023 Apr 4;15(7)
Nutrients 2023 Apr 4;15(7)
Organotypic 3D Co-Culture of Human Pleura as a Novel In Vitro Model of Staphylococcus aureus Infection and Biofilm Development.
Kurow O, Nuwayhid R, Stock P, Steinert M, Langer S, Krämer S, Metelmann IB
Bioengineering (Basel, Switzerland) 2023 Apr 27;10(5)
Bioengineering (Basel, Switzerland) 2023 Apr 27;10(5)
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis.
Guo HH, Shen HR, Tang MZ, Sheng N, Ding X, Lin Y, Zhang JL, Jiang JD, Gao TL, Wang LL, Han YX
Journal of ethnopharmacology 2023 Apr 24;306:116158
Journal of ethnopharmacology 2023 Apr 24;306:116158
Huangkui capsule alleviates doxorubicin-induced proteinuria via protecting against podocyte damage and inhibiting JAK/STAT signaling.
Zhao L, Han S, Chai C
Journal of ethnopharmacology 2023 Apr 24;306:116150
Journal of ethnopharmacology 2023 Apr 24;306:116150
Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver disease in high-fat diet-induced obese mice.
Wang M, Li L, Qian J, Wang N, Bao J, Lu J, Chen F, Li Y, Zhang Y, Yan F
iScience 2023 Apr 21;26(4):106346
iScience 2023 Apr 21;26(4):106346
Cadmium-induced Sertoli Cell Injury Through p38-MAPK and Related Signaling Proteins-A Study by RNA Sequencing.
Wang L, Li X, Bu T, Wu X, Li L, Gao S, Yun D, Zhang Y, Chen H, Sun F, Cheng CY
Endocrinology 2023 Apr 17;164(6)
Endocrinology 2023 Apr 17;164(6)
Lactational exposure to Deoxynivalenol causes mammary gland injury via inducing inflammatory response and impairing blood-milk barrier integrity in mice.
Sun P, Zhao X, Liu M, Wu H, Lv C, Zhou S, Ding Z, Huo L, Yang L, Liang A
Ecotoxicology and environmental safety 2023 Apr 15;255:114773
Ecotoxicology and environmental safety 2023 Apr 15;255:114773
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Yang B, Xiong Z, Lin M, Yang Y, Chen Y, Zeng J, Jia X, Feng L
International journal of biological macromolecules 2023 Apr 15;234:123767
International journal of biological macromolecules 2023 Apr 15;234:123767
Mitochondrial-targeting fluorescent small molecule IR-780 alleviates radiation-induced brain injury.
Zhang C, Zheng J, Chen W, Yang W, Tan X, Fan X, Shen G, Qu L, Chen Z, Shi C
Brain research 2023 Apr 15;1805:148285
Brain research 2023 Apr 15;1805:148285
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Liu C, Lu J, Yuan T, Xie L, Zhang L
Scientific reports 2023 Apr 14;13(1):6126
Scientific reports 2023 Apr 14;13(1):6126
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
Lin L, Yang J, Zhang D, Lv Q, Wang F, Liu P, Wang M, Shi C, Huang X, Liang W, Tan C, Wang X, Chen H, Wilson BA, Wu B, Peng Z
Microbiology spectrum 2023 Apr 13;11(2):e0455422
Microbiology spectrum 2023 Apr 13;11(2):e0455422
Construction of a three-dimensional urothelium on-chip with barrier function based on urinary flow microenvironment.
Hou C, Gu Y, Yuan W, Zhang W, Xiu X, Lin J, Gao Y, Liu P, Chen X, Song L
Biofabrication 2023 Apr 11;15(3)
Biofabrication 2023 Apr 11;15(3)
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Li J, Bai J, Si X, Jia H, Wu Z
Chemico-biological interactions 2023 Apr 1;374:110386
Chemico-biological interactions 2023 Apr 1;374:110386
Kinase Activity Is Not Required for G Protein-Coupled Receptor Kinase 4 Restraining mTOR Signaling during Cilia and Kidney Development.
Gerhards J, Maerz LD, Matthees ESF, Donow C, Moepps B, Premont RT, Burkhalter MD, Hoffmann C, Philipp M
Journal of the American Society of Nephrology : JASN 2023 Apr 1;34(4):590-606
Journal of the American Society of Nephrology : JASN 2023 Apr 1;34(4):590-606
A leaky human colon model reveals uncoupled apical/basal cytotoxicity in early Clostridioides difficile toxin exposure.
Ok MT, Liu J, Bliton RJ, Hinesley CM, San Pedro EET, Breau KA, Gomez-Martinez I, Burclaff J, Magness ST
American journal of physiology. Gastrointestinal and liver physiology 2023 Apr 1;324(4):G262-G280
American journal of physiology. Gastrointestinal and liver physiology 2023 Apr 1;324(4):G262-G280
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Yang Y, Zheng S, Chu H, Du C, Chen M, Emran MY, Chen J, Yang F, Tian L
Toxins 2023 Apr 1;15(4)
Toxins 2023 Apr 1;15(4)
Selenoprotein W Ameliorates Experimental Colitis and Promotes Intestinal Epithelial Repair.
Nettleford SK, Liao C, Short SP, Rossi RM, Singh V, Prabhu KS
Antioxidants (Basel, Switzerland) 2023 Apr 1;12(4)
Antioxidants (Basel, Switzerland) 2023 Apr 1;12(4)
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Rehman AU, Siddiqui NZ, Farooqui NA, Alam G, Gul A, Ahmad B, Asim M, Khan AI, Xin Y, Zexu W, Song Ju H, Xin W, Lei S, Wang L
Frontiers in nutrition 2022;9:984695
Frontiers in nutrition 2022;9:984695
Probiotic Lactobacillus rhamnosus GR-1 supplementation attenuates Pb-induced learning and memory deficits by reshaping the gut microbiota.
Gu X, Bi N, Wang T, Huang C, Wang R, Xu Y, Wang HL
Frontiers in nutrition 2022;9:934118
Frontiers in nutrition 2022;9:934118
Lactobacillus fermentum CECT5716 Alleviates the Inflammatory Response in Asthma by Regulating TLR2/TLR4 Expression.
Wang W, Li Y, Han G, Li A, Kong X
Frontiers in nutrition 2022;9:931427
Frontiers in nutrition 2022;9:931427
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
He C, Gao M, Zhang X, Lei P, Yang H, Qing Y, Zhang L
Frontiers in nutrition 2022;9:893344
Frontiers in nutrition 2022;9:893344
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Li P, Li M, Song Y, Huang X, Wu T, Xu ZZ, Lu H
Frontiers in nutrition 2022;9:832848
Frontiers in nutrition 2022;9:832848
Blue Light Induces RPE Cell Necroptosis, Which Can Be Inhibited by Minocycline.
Song W, Zhu R, Gao W, Xing C, Yang L
Frontiers in medicine 2022;9:831463
Frontiers in medicine 2022;9:831463
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
Song Q, Chen P, Wu SJ, Chen Y, Zhang Y
Frontiers in cardiovascular medicine 2022;9:746888
Frontiers in cardiovascular medicine 2022;9:746888
Bacteroides fragilis strain ZY-312 promotes intestinal barrier integrity via upregulating the STAT3 pathway in a radiation-induced intestinal injury mouse model.
Zhou Q, Shen B, Huang R, Liu H, Zhang W, Song M, Liu K, Lin X, Chen S, Liu Y, Wang Y, Zhi F
Frontiers in nutrition 2022;9:1063699
Frontiers in nutrition 2022;9:1063699
Tannic acid attenuates intestinal oxidative damage by improving antioxidant capacity and intestinal barrier in weaned piglets and IPEC-J2 cells.
Wang M, Huang H, Wang L, Yin L, Yang H, Chen C, Zheng Q, He S
Frontiers in nutrition 2022;9:1012207
Frontiers in nutrition 2022;9:1012207
Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.
Peng H, Jin L, Zhang Q, Shen Y, Wang Z, Zhou F, Yu Q
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7412331
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7412331
Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.
Ren C, Hu C, Wu Y, Li T, Zou A, Yu D, Shen T, Cai W, Yu J
Oxidative medicine and cellular longevity 2022;2022:5961123
Oxidative medicine and cellular longevity 2022;2022:5961123
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y, Wang J, Wang X, Zhang J, Shao A
Oxidative medicine and cellular longevity 2022;2022:4295208
Oxidative medicine and cellular longevity 2022;2022:4295208
Effects of Lipolysis-Stimulated Lipoprotein Receptor on Tight Junctions of Pancreatic Ductal Epithelial Cells in Hypertriglyceridemic Acute Pancreatitis.
Wang J, Qin M, Wu Q, Yang H, Wei B, Xie J, Qin Y, Liang Z, Huang J
BioMed research international 2022;2022:4234186
BioMed research international 2022;2022:4234186
Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway.
Niu S, Jing M, Wen J, Wei S, Li H, Li X, Ma X, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3498310
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3498310
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Wang L, Wang J
Oxidative medicine and cellular longevity 2022;2022:1755608
Oxidative medicine and cellular longevity 2022;2022:1755608
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
Li J, Yang T, Wang Q, Li Y, Wu H, Zhang M, Qi H, Zhang H, Li J
International journal of biological sciences 2022;18(9):3576-3591
International journal of biological sciences 2022;18(9):3576-3591
The effect of a fennel seed extract on the STAT signaling and intestinal barrier function.
Das B, Rabalais J, Kozan P, Lu T, Durali N, Okamoto K, McGeough MD, Lee BJ, Barrett KE, Marchelletta R, Sivagnanam M
PloS one 2022;17(7):e0271045
PloS one 2022;17(7):e0271045
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
Sun J, Zhang W
PloS one 2022;17(3):e0266084
PloS one 2022;17(3):e0266084
The SARS-CoV-2 envelope protein disrupts barrier function in an in vitro human blood-brain barrier model.
Ju J, Su Y, Zhou Y, Wei H, Xu Q
Frontiers in cellular neuroscience 2022;16:897564
Frontiers in cellular neuroscience 2022;16:897564
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage.
Guo H, Zhang W, Wang Z, Li Z, Zhou J, Yang Z
Frontiers in molecular neuroscience 2022;15:977941
Frontiers in molecular neuroscience 2022;15:977941
Selenium-enriched Bifidobacterium longum DD98 effectively ameliorates dextran sulfate sodium-induced ulcerative colitis in mice.
Hu Y, Jin X, Gao F, Lin T, Zhu H, Hou X, Yin Y, Kan S, Chen D
Frontiers in microbiology 2022;13:955112
Frontiers in microbiology 2022;13:955112
Preventive effects of the Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple on chronic kidney disease rats via modulating the intestinal microbiota and enhancing the intestinal barrier.
Wang L, Zhu JH, Jiang XD, Ma ZX, Tao JH
Frontiers in pharmacology 2022;13:942032
Frontiers in pharmacology 2022;13:942032
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Li B, Wang HY, Huang JH, Xu WF, Feng XJ, Xiong ZP, Dong YJ, Li LZ, He X, Wu HS, Zhang K, Su J, Yu QX, Jiang NH, Lv GY, Chen SH
Frontiers in pharmacology 2022;13:935714
Frontiers in pharmacology 2022;13:935714
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Wang Z, Yin L, Qi Y, Zhang J, Zhu H, Tang J
Frontiers in microbiology 2022;13:934786
Frontiers in microbiology 2022;13:934786
Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway.
Wang K, Chen D, Yu B, He J, Mao X, Huang Z, Yan H, Wu A, Luo Y, Zheng P, Yu J, Luo J
Frontiers in immunology 2022;13:921613
Frontiers in immunology 2022;13:921613
Tryptophan Supplementation Enhances Intestinal Health by Improving Gut Barrier Function, Alleviating Inflammation, and Modulating Intestinal Microbiome in Lipopolysaccharide-Challenged Piglets.
Liu G, Lu J, Sun W, Jia G, Zhao H, Chen X, Kim IH, Zhang R, Wang J
Frontiers in microbiology 2022;13:919431
Frontiers in microbiology 2022;13:919431
Qingchang Wenzhong Decoction Prevents the Occurrence of Intestinal Tumors by Regulating Intestinal Microbiota and Gasdermin E.
Ren L, Zhang Z, Zhao W, Zhao B, Chen X, Wang Y, Chen Z, Ye J, Yang Y, Cao P
Frontiers in physiology 2022;13:917323
Frontiers in physiology 2022;13:917323
Integrated analysis of inflammatory response subtype-related signature to predict clinical outcomes, immune status and drug targets in lower-grade glioma.
Cao Y, Zhu H, Chen Q, Huang H, Xie D, Li X, Jiang X, Ren C, Peng J
Frontiers in pharmacology 2022;13:914667
Frontiers in pharmacology 2022;13:914667
Effect of Tanshinone IIA on Gut Microbiome in Diabetes-Induced Cognitive Impairment.
Zheng Y, Zhou X, Wang C, Zhang J, Chang D, Liu W, Zhu M, Zhuang S, Shi H, Wang X, Chen Y, Cheng Z, Lin Y, Nan L, Sun Y, Min L, Liu J, Chen J, Zhang J, Huang M
Frontiers in pharmacology 2022;13:890444
Frontiers in pharmacology 2022;13:890444
Shenling Baizhu Powder Alleviates TNBS-Induced Colitis in Rats by Improving Intestinal Epithelial Permeability and Inhibiting Inflammation Through the TLR5/MyD88/NF-κB Pathway.
Rao K, Qin S, Yang Y, Zhan K, Wu H, Zheng H, Huang S
Frontiers in pharmacology 2022;13:883918
Frontiers in pharmacology 2022;13:883918
Transepithelial Secretion of Mucosal IgM Mediated by Polymeric Immunoglobulin Receptor of Flounder (Paralichthys olivaceus): In-Vivo and In-Vitro Evidence.
Sheng X, Guo Y, Zhu H, Chai B, Tang X, Xing J, Chi H, Zhan W
Frontiers in immunology 2022;13:868753
Frontiers in immunology 2022;13:868753
Artemisinin analog SM934 alleviates epithelial barrier dysfunction via inhibiting apoptosis and caspase-1-mediated pyroptosis in experimental colitis.
Shao M, Yan Y, Zhu F, Yang X, Qi Q, Yang F, Hao T, Lin Z, He P, Zhou Y, Tang W, He S, Zuo J
Frontiers in pharmacology 2022;13:849014
Frontiers in pharmacology 2022;13:849014
Human Fecal Microbiota Transplantation Reduces the Susceptibility to Dextran Sulfate Sodium-Induced Germ-Free Mouse Colitis.
Yang Y, Zheng X, Wang Y, Tan X, Zou H, Feng S, Zhang H, Zhang Z, He J, Cui B, Zhang X, Wu Z, Dong M, Cheng W, Tao S, Wei H
Frontiers in immunology 2022;13:836542
Frontiers in immunology 2022;13:836542
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in pharmacology 2022;13:834948
Frontiers in pharmacology 2022;13:834948
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Zhang R, Xie L, Wu F, Xu J, Lu L, Cao L, Li L, Meng W, Zhang H, Shao C, Li X, Chen D
Frontiers in pharmacology 2022;13:828896
Frontiers in pharmacology 2022;13:828896
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348
Frontiers in physiology 2022;13:822348
Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis.
Ghosh S, Moorthy B, Haribabu B, Jala VR
Frontiers in immunology 2022;13:1004603
Frontiers in immunology 2022;13:1004603
Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis.
Ghosh S, Singh R, Vanwinkle ZM, Guo H, Vemula PK, Goel A, Haribabu B, Jala VR
Theranostics 2022;12(12):5574-5595
Theranostics 2022;12(12):5574-5595
Liujunanwei decoction attenuates cisplatin-induced nausea and vomiting in a Rat-Pica model partially mediated by modulating the gut micsrobiome.
Chen D, Guo Y, Yang Y
Frontiers in cellular and infection microbiology 2022;12:876781
Frontiers in cellular and infection microbiology 2022;12:876781
Correlation Analysis of Gut Microbiota and Serum Metabolome With Porphyromonas gingivalis-Induced Metabolic Disorders.
Dong Z, Lv W, Zhang C, Chen S
Frontiers in cellular and infection microbiology 2022;12:858902
Frontiers in cellular and infection microbiology 2022;12:858902
Effects of Zhishi Daozhi Decoction on the intestinal flora of nonalcoholic fatty liver disease mice induced by a high-fat diet.
Bi CR, Sun JT, Du J, Chu LY, Li YJ, Jia XY, Liu Y, Zhang WP, Li YC, Liu YJ
Frontiers in cellular and infection microbiology 2022;12:1005318
Frontiers in cellular and infection microbiology 2022;12:1005318
Telomerase reverse transcriptase promotes angiogenesis in neonatal rats after hypoxic-ischemic brain damage.
Li J, Feng Y, Zhao J, Fang Z, Liu H
PeerJ 2022;10:e14220
PeerJ 2022;10:e14220
A Platform for Co-Culture of Primary Human Colonic Epithelium With Anaerobic Probiotic Bacteria.
Kim R, Wang Y, Sims CE, Allbritton NL
Frontiers in bioengineering and biotechnology 2022;10:890396
Frontiers in bioengineering and biotechnology 2022;10:890396
Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis.
Li X, Li Q, Xiong B, Chen H, Wang X, Zhang D
Pharmacological research 2022 Sep;183:106368
Pharmacological research 2022 Sep;183:106368
Complement factor B inhibitor LNP023 improves lupus nephritis in MRL/lpr mice.
Chen K, Deng Y, Shang S, Tang L, Li Q, Bai X, Chen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113433
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113433
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells.
Lin Z, Chen L, Cheng M, Zhu F, Yang X, Zhao W, Zuo J, He S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113399
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113399
Exercise protects intestinal epithelial barrier from high fat diet- induced permeabilization through SESN2/AMPKα1/HIF-1α signaling.
Yu C, Liu S, Niu Y, Fu L
The Journal of nutritional biochemistry 2022 Sep;107:109059
The Journal of nutritional biochemistry 2022 Sep;107:109059
Glutamine in suppression of lipopolysaccharide-induced piglet intestinal inflammation: The crosstalk between AMPK activation and mitochondrial function.
He L, Zhou X, Wu Z, Feng Y, Liu D, Li T, Yin Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:137-147
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:137-147
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Zhang K, Xu Y, Yang Y, Guo M, Zhang T, Zong B, Huang S, Suo L, Ma B, Wang X, Wu Y, Brugger D, Chen Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions.
Shan Q, Liu N, Wang X, Zhu Y, Yin J, Wang J
Journal of animal science and biotechnology 2022 Sep 9;13(1):101
Journal of animal science and biotechnology 2022 Sep 9;13(1):101
Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities.
Zhao Y, Zhang T, Shen X, Huang A, Li H, Wang L, Liu X, Wang X, Song X, Wang S, Dong J, Shao N
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Sep 7;30(9):3052-3065
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Sep 7;30(9):3052-3065
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
Rehman AU, Khan AI, Xin Y, Liang W
AMB Express 2022 Sep 3;12(1):114
AMB Express 2022 Sep 3;12(1):114
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Siddiqui NZ, Rehman AU, Yousuf W, Khan AI, Farooqui NA, Zang S, Xin Y, Wang L
Gut pathogens 2022 Sep 17;14(1):39
Gut pathogens 2022 Sep 17;14(1):39
Protective Effects and Mechanism of a Novel Probiotic Strain Ligilactobacillus salivarius YL20 against Cronobacter sakazakii-Induced Necrotizing Enterocolitis In Vitro and In Vivo.
Wang W, Geng M, Zhu C, Huang L, Zhang Y, Zhang T, Zhao C, Zhang T, Du X, Wang N
Nutrients 2022 Sep 16;14(18)
Nutrients 2022 Sep 16;14(18)
Effect and Mechanism of Pharmaceutical Excipients on Berberine to Alleviate Ulcerative Colitis via Regulating Gut Microbiota.
Wu C, Zheng T, Chen H, Zou P, Zhang M, Wang J, Li N, Zhang Y, Li Y, Dong Z
Molecules (Basel, Switzerland) 2022 Sep 15;27(18)
Molecules (Basel, Switzerland) 2022 Sep 15;27(18)
Phytic Acid Improves Hepatic Steatosis, Inflammation, and Oxidative Stress in High-Fat Diet (HFD)-Fed Mice by Modulating the Gut-Liver Axis.
Ran X, Hu G, He F, Li K, Li F, Xu D, Liu J, Fu S
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11401-11411
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11401-11411
Periplaneta americana Extract Pretreatment Alleviates Oxidative Stress and Inflammation and Increases the Abundance of Gut Akkermansia muciniphila in Diquat-Induced Mice.
Lu S, Xu S, Chen L, Deng Y, Feng J
Antioxidants (Basel, Switzerland) 2022 Sep 13;11(9)
Antioxidants (Basel, Switzerland) 2022 Sep 13;11(9)
Mo(3)Se(4) nanoparticle with ROS scavenging and multi-enzyme activity for the treatment of DSS-induced colitis in mice.
Guo H, Guo H, Xie Y, Chen Y, Lu C, Yang Z, Zhu Y, Ouyang Y, Zhang Y, Wang X
Redox biology 2022 Oct;56:102441
Redox biology 2022 Oct;56:102441
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.
Xie H, Shi Y, Zhou Y, Liu H
Molecular biology reports 2022 Oct;49(10):9181-9194
Molecular biology reports 2022 Oct;49(10):9181-9194
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Liping Y, Xinglin YU, Chao Z, Pu C, Xiaohua D
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):707-714
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):707-714
Chromatin remodeler Znhit1 controls bone morphogenetic protein signaling in embryonic lung tissue branching.
Wei W, Tang X, Jiang N, Ni C, He H, Sun S, Yu M, Yu C, Qiu M, Yan D, Zhou Z, Song Y, Liu H, Zhao B, Lin X
The Journal of biological chemistry 2022 Oct;298(10):102490
The Journal of biological chemistry 2022 Oct;298(10):102490
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Zhang J, Li Q, Zhang X, Chen Y, Lu Y, Wang X, Zhang L, Wang T
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
Rice Protein Peptides Alleviate Dextran Sulfate Sodium-Induced Colitis via the Keap1-Nrf2 Signaling Pathway and Regulating Gut Microbiota.
Yang W, Huang Z, Xiong H, Wang J, Zhang H, Guo F, Wang C, Sun Y
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12469-12483
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12469-12483
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Zhang D, Chang R, Ren Y, He Y, Guo S, Guan F, Yao M
International journal of biological macromolecules 2022 Oct 31;219:844-863
International journal of biological macromolecules 2022 Oct 31;219:844-863
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT
iScience 2022 Oct 21;25(10):105050
iScience 2022 Oct 21;25(10):105050
Network Pharmacology Analysis and Experimental Validation of Kaempferol in the Treatment of Ischemic Stroke by Inhibiting Apoptosis and Regulating Neuroinflammation Involving Neutrophils.
Zhang SS, Liu M, Liu DN, Shang YF, Du GH, Wang YH
International journal of molecular sciences 2022 Oct 21;23(20)
International journal of molecular sciences 2022 Oct 21;23(20)
Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema.
Xue Y, Wang X, Wan B, Wang D, Li M, Cheng K, Luo Q, Wang D, Lu Y, Zhu L
Cell communication and signaling : CCS 2022 Oct 17;20(1):160
Cell communication and signaling : CCS 2022 Oct 17;20(1):160
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
Zhong X, Chen Z, Wang Y, Mao M, Deng Y, Shi M, Xu Y, Chen L, Cao W
Brain research bulletin 2022 Oct 15;189:174-183
Brain research bulletin 2022 Oct 15;189:174-183
The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice.
Zhou W, Wu WH, Si ZL, Liu HL, Wang H, Jiang H, Liu YF, Alolga RN, Chen C, Liu SJ, Bian XY, Shan JJ, Li J, Tan NH, Zhang ZH
Nature communications 2022 Oct 14;13(1):6081
Nature communications 2022 Oct 14;13(1):6081
Restored intestinal integrity, nutrients transporters, energy metabolism, antioxidative capacity and decreased harmful microbiota were associated with IUGR piglet's catch-up growth before weanling.
Cui C, Wu C, Wang J, Ma Z, Zheng X, Zhu P, Wang N, Zhu Y, Guan W, Chen F
Journal of animal science and biotechnology 2022 Oct 14;13(1):129
Journal of animal science and biotechnology 2022 Oct 14;13(1):129
Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.
Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J
Human molecular genetics 2022 Oct 10;31(20):3504-3520
Human molecular genetics 2022 Oct 10;31(20):3504-3520
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Yu R, Zhong J, Zhou Q, Ren W, Liu Z, Bian Y
Chemico-biological interactions 2022 Oct 1;366:110135
Chemico-biological interactions 2022 Oct 1;366:110135
Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice.
Cai G, Wu C, Mao N, Song Z, Yu L, Zhu T, Peng S, Yang Y, Liu Z, Wang D
International journal of biological macromolecules 2022 Oct 1;218:356-367
International journal of biological macromolecules 2022 Oct 1;218:356-367
P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy.
Huang L, Chen Y, Liu R, Li B, Fei X, Li X, Liu G, Li Y, Xu B, Fang W
Aging and disease 2022 Oct 1;13(5):1546-1561
Aging and disease 2022 Oct 1;13(5):1546-1561
Betaine Ameliorates Acute Sever Ulcerative Colitis by Inhibiting Oxidative Stress Induced Inflammatory Pyroptosis.
Chen L, Liu D, Mao M, Liu W, Wang Y, Liang Y, Cao W, Zhong X
Molecular nutrition & food research 2022 Nov;66(22):e2200341
Molecular nutrition & food research 2022 Nov;66(22):e2200341
Suspended Collagen Hydrogels to Replicate Human Colonic Epithelial Cell Interactions with Immune Cells.
Hinman SS, Massaro A, Wang Y, Sims CE, Kim R, Allbritton NL
Advanced biology 2022 Nov;6(11):e2200129
Advanced biology 2022 Nov;6(11):e2200129
Metabolites of Latilactobacillus curvatus BYB3 and Indole Activate Aryl Hydrocarbon Receptor to Attenuate Lipopolysaccharide-Induced Intestinal Barrier Dysfunction.
Wang X, Yong CC, Oh S
Food science of animal resources 2022 Nov;42(6):1046-1060
Food science of animal resources 2022 Nov;42(6):1046-1060
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Wang B, Zhang H, Chen YF, Hu LQ, Tian YY, Tong HW, Wang G, Chen C, Yuan P
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Lin S, Li Q, Xu Z, Chen Z, Tao Y, Tong Y, Wang T, Chen S, Wang P
Psychopharmacology 2022 Nov;239(11):3657-3677
Psychopharmacology 2022 Nov;239(11):3657-3677
Neutrophil extracellular traps: A novel therapeutic target for intracranial hemorrhage.
Jin J, Zhao X, Li W, Wang F, Tian J, Wang N, Gao X, Zhang J, Wu J, Mang G, Ma R, Hu S
Thrombosis research 2022 Nov;219:1-13
Thrombosis research 2022 Nov;219:1-13
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Zhan L, Zheng J, Meng J, Fu D, Pang L, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
Xiaojianzhong decoction attenuates gastric mucosal injury by activating the p62/Keap1/Nrf2 signaling pathway to inhibit ferroptosis.
Chen J, Zhang J, Chen T, Bao S, Li J, Wei H, Hu X, Liang Y, Liu F, Yan S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113631
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113631
Luteolin alleviates ulcerative colitis by restoring the balance of NCR(-)ILC3/NCR(+)ILC3 to repairing impaired intestinal barrier.
Xie X, Zhao M, Huang S, Li P, Chen P, Luo X, Wang Q, Pan Z, Li X, Chen J, Chen B, Zhou L
International immunopharmacology 2022 Nov;112:109251
International immunopharmacology 2022 Nov;112:109251
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
Wang N, Yang Y, Liu Y, Huang L, Gu M, Wu Y, Xu L, Sun H, Guo W
International immunopharmacology 2022 Nov;112:109242
International immunopharmacology 2022 Nov;112:109242
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Hypoxia-Induced HIF-1α Expression Promotes Neurogenic Bladder Fibrosis via EMT and Pyroptosis.
Li Q, Hong Y, Chen J, Zhou X, Tian X, Yu Y, Shen L, Long C, Cai M, Wu S, Wei G
Cells 2022 Nov 29;11(23)
Cells 2022 Nov 29;11(23)
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
Chen Y, Tang L, Ye X, Chen Y, Shan E, Han H, Zhong C
Food & function 2022 Nov 28;13(23):12363-12370
Food & function 2022 Nov 28;13(23):12363-12370
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Song K, Yang X, An G, Xia X, Zhao J, Xu X, Wan C, Liu T, Zheng Y, Ren S, Wang M, Chang G, Cronin SJF, Penninger JM, Jing T, Ou X, Rao S, Liu Z, Zhao XY
Nature communications 2022 Nov 28;13(1):7335
Nature communications 2022 Nov 28;13(1):7335
New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway.
Gu X, Miao Z, Wang Y, Yang Y, Yang T, Xu Y
BMC complementary medicine and therapies 2022 Nov 24;22(1):307
BMC complementary medicine and therapies 2022 Nov 24;22(1):307
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
Xu D, Zhuang L, Gao S, Ma H, Cheng J, Liu J, Liu D, Fu S, Hu G
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14718-14731
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14718-14731
FGF2 isoforms play distinct roles in tubular epithelial-to-mesenchymal transition in diabetic nephropathy.
Luo Y, Deng D, Lin L, Zhou Y, Wang L, Zou X, Wang X
Experimental cell research 2022 Nov 15;420(2):113355
Experimental cell research 2022 Nov 15;420(2):113355
Gestational PCB52 exposure induces hepatotoxicity and intestinal injury by activating inflammation in dam and offspring mice: A maternal and progeny study.
Xu LL, Zhang QY, Chen YK, Chen LJ, Zhang KK, Wang Q, Xie XL
Environmental pollution (Barking, Essex : 1987) 2022 Nov 15;313:120186
Environmental pollution (Barking, Essex : 1987) 2022 Nov 15;313:120186
DHA-enriched phosphatidylcholine from Clupea harengus roes regulates the gut-liver axis to ameliorate high-fat diet-induced non-alcoholic fatty liver disease.
Qian L, Tian S, Jiang S, Tang Y, Han T
Food & function 2022 Nov 14;13(22):11555-11567
Food & function 2022 Nov 14;13(22):11555-11567
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Li T, Zhai D, Zhang M, Ye R, Kuang X, Shao N, Bi J, Lin Y
Cancer letters 2022 Nov 1;548:215904
Cancer letters 2022 Nov 1;548:215904
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Yang G, Cao Y, Wang P, Mei L, Chen J, Lu W
The Journal of surgical research 2022 May;273:247-254
The Journal of surgical research 2022 May;273:247-254
Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury.
Zhao R, Wu X, Bi XY, Yang H, Zhang Q
Neural regeneration research 2022 May;17(5):1080-1087
Neural regeneration research 2022 May;17(5):1080-1087
Galactooligosaccharides as a protective agent for intestinal barrier and its regulatory functions for intestinal microbiota.
Wang G, Wang H, Jin Y, Xiao Z, Umar Yaqoob M, Lin Y, Chen H, Wang M
Food research international (Ottawa, Ont.) 2022 May;155:111003
Food research international (Ottawa, Ont.) 2022 May;155:111003
Effect of dendrobium mixture in alleviating diabetic cognitive impairment associated with regulating gut microbiota.
Zheng Y, Zhou X, Wang C, Zhang J, Chang D, Zhuang S, Xu W, Chen Y, Wang X, Nan L, Sun Y, Lin X, Lin W, He C, Dai L, Zhang J, Chen J, Shi H, Huang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112891
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112891
Comparison of five diarrhea-predominant irritable bowel syndrome (IBS-D) rat models in the brain-gut-microbiota axis.
Wu H, Zhan K, Rao K, Zheng H, Qin S, Tang X, Huang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112811
miR-145-5p targets MMP2 to protect brain injury in hypertensive intracerebral hemorrhage via inactivation of the Wnt/β-catenin signaling pathway.
Xiao W, Jiang Z, Wan W, Pan W, Xu J
Annals of translational medicine 2022 May;10(10):571
Annals of translational medicine 2022 May;10(10):571
Human branching cholangiocyte organoids recapitulate functional bile duct formation.
Roos FJM, van Tienderen GS, Wu H, Bordeu I, Vinke D, Albarinos LM, Monfils K, Niesten S, Smits R, Willemse J, Rosmark O, Westergren-Thorsson G, Kunz DJ, de Wit M, French PJ, Vallier L, IJzermans JNM, Bartfai R, Marks H, Simons BD, van Royen ME, Verstegen MMA, van der Laan LJW
Cell stem cell 2022 May 5;29(5):776-794.e13
Cell stem cell 2022 May 5;29(5):776-794.e13
Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.
Zhang K, Lian S, Shen X, Zhao X, Zhao W, Li C
International journal of biological macromolecules 2022 May 31;208:890-900
International journal of biological macromolecules 2022 May 31;208:890-900
JAC4 Protects from X-ray Radiation-Induced Intestinal Injury by JWA-Mediated Anti-Oxidation/Inflammation Signaling.
Zhou Y, Liu J, Li X, Wang L, Hu L, Li A, Zhou J
Antioxidants (Basel, Switzerland) 2022 May 27;11(6)
Antioxidants (Basel, Switzerland) 2022 May 27;11(6)
Chromogranin A-derived peptide CGA47-66 protects against septic brain injury by reducing blood-brain barrier damage through the PI3K/AKT pathway.
Wang F, Zeng Y, Liu X, Cao J, Kang S, Zhou W, Chen X, Liu J, Zhang D
Biochemical and biophysical research communications 2022 May 21;605:162-170
Biochemical and biophysical research communications 2022 May 21;605:162-170
Methamphetamine induces intestinal injury by altering gut microbiota and promoting inflammation in mice.
Wang LB, Xu LL, Chen LJ, Zhang KK, Zhang QY, Chen YK, Li JH, Liu JL, Wang Q, Xie XL
Toxicology and applied pharmacology 2022 May 15;443:116011
Toxicology and applied pharmacology 2022 May 15;443:116011
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
Li J, Li Y, Liu P, Wang X, Ma Y, Zhong Q, Yang Q
Journal of virology 2022 May 11;96(9):e0038022
Journal of virology 2022 May 11;96(9):e0038022
Phloretin Protects Bovine Rumen Epithelial Cells from LPS-Induced Injury.
Wang K, Lei Q, Ma H, Jiang M, Yang T, Ma Q, Datsomor O, Zhan K, Zhao G
Toxins 2022 May 11;14(5)
Toxins 2022 May 11;14(5)
Gestational exposure to GenX induces hepatic alterations by the gut-liver axis in maternal mice: A similar mechanism as PFOA.
Xu LL, Chen YK, Zhang QY, Chen LJ, Zhang KK, Li JH, Liu JL, Wang Q, Xie XL
The Science of the total environment 2022 May 10;820:153281
The Science of the total environment 2022 May 10;820:153281
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Xiong T, Zheng X, Zhang K, Wu H, Dong Y, Zhou F, Cheng B, Li L, Xu W, Su J, Huang J, Jiang Z, Li B, Zhang B, Lv G, Chen S
Journal of ethnopharmacology 2022 May 10;289:115001
Journal of ethnopharmacology 2022 May 10;289:115001
Astilbin from Smilax glabra Roxb. alleviates high-fat diet-induced metabolic dysfunction.
Wang T, Ye Y, Ji J, Zhang S, Yang X, Xu J, Wang JS, Chen Z, Xia B, Shen H, Xia R, Shi W, Sun X
Food & function 2022 May 10;13(9):5023-5036
Food & function 2022 May 10;13(9):5023-5036
Diet composition affects long-term zearalenone exposure on the gut-blood-liver axis metabolic dysfunction in mice.
Wang T, Ye Y, Ji J, Yang X, Xu J, Wang JS, Han X, Zhang T, Sun X
Ecotoxicology and environmental safety 2022 May 1;236:113466
Ecotoxicology and environmental safety 2022 May 1;236:113466
Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats.
Zhang M, Yang L, Zhu M, Yang B, Yang Y, Jia X, Feng L
International journal of biological macromolecules 2022 May 1;206:849-860
International journal of biological macromolecules 2022 May 1;206:849-860
Dietary ferulic acid and vanillic acid on inflammation, gut barrier function and growth performance in lipopolysaccharide-challenged piglets.
Hu R, Wu S, Li B, Tan J, Yan J, Wang Y, Tang Z, Liu M, Fu C, Zhang H, He J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):144-152
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):144-152
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J
Veterinary microbiology 2022 Mar;266:109367
Veterinary microbiology 2022 Mar;266:109367
Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats.
Yang R, Shen YJ, Chen M, Zhao JY, Chen SH, Zhang W, Song JK, Li L, Du GH
Journal of Asian natural products research 2022 Mar;24(3):278-289
Journal of Asian natural products research 2022 Mar;24(3):278-289
M1 macrophages impair tight junctions between endothelial cells after spinal cord injury.
Luo Y, Yao F, Hu X, Li Y, Chen Y, Li Z, Zhu Z, Yu S, Tian D, Cheng L, Zheng M, Jing J
Brain research bulletin 2022 Mar;180:59-72
Brain research bulletin 2022 Mar;180:59-72
Alterations in the expression level of visfatin in the lungs of piglets infected with PRRSV and its effect on PRRSV replication.
Zhang ZW, Ansari AR, Dong L, Niu XY, Yang WJ, Li HZ, Xu FL, Yang KL, Song H
Microbial pathogenesis 2022 Mar;164:105443
Microbial pathogenesis 2022 Mar;164:105443
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
Tan C, Fan H, Ding J, Han C, Guan Y, Zhu F, Wu H, Liu Y, Zhang W, Hou X, Tan S, Tang Q
Materials today. Bio 2022 Mar;14:100246
Materials today. Bio 2022 Mar;14:100246
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Du L, Hao YM, Yang YH, Zheng Y, Wu ZJ, Zhou MQ, Wang BZ, Wang YM, Wu H, Su GH
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2911-2922
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2911-2922
Apple polyphenol extract modulates bile acid metabolism and gut microbiota by regulating the circadian rhythms in daytime-restricted high fat diet feeding C57BL/6 male mice.
Cui Y, Yin Y, Li S, Wu Z, Xie Y, Qian Q, Yang H, Li X
Food & function 2022 Mar 7;13(5):2805-2822
Food & function 2022 Mar 7;13(5):2805-2822
Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway.
Hu J, Wang X, Chen X, Fang Y, Chen K, Peng W, Wang Z, Guo K, Tan X, Liang F, Lin L, Xiong Y
Journal of neuroinflammation 2022 Mar 28;19(1):71
Journal of neuroinflammation 2022 Mar 28;19(1):71
Bioactive triple peptide inhibits inflammasome activation to alleviate Salmonella-induced intestinal inflammation in mice via modulation of host defense and bacterial virulence.
Cui C, Liu Q, Duan B, Liu X, Wei H, Peng J
Food & function 2022 Mar 21;13(6):3512-3525
Food & function 2022 Mar 21;13(6):3512-3525
Effect of TRAF6 in acute pancreatitis-induced intestinal barrier injury via TLR4/NF-κB signal pathway.
Wei B, Wu Q, Yang X, Lai C, Su Z, Liang Z
Tissue & cell 2022 Jun;76:101792
Tissue & cell 2022 Jun;76:101792
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Liu C, Sun W, Zhu T, Shi S, Zhang J, Wang J, Gao F, Ou Q, Jin C, Li J, Xu JY, Zhang J, Tian H, Xu GT, Lu L
Redox biology 2022 Jun;52:102292
Redox biology 2022 Jun;52:102292
Inhibition of galectin-3 ameliorates high-glucose-induced oxidative stress and inflammation in ARPE-19 cells.
Li M, Tian M, Jiang X, Liu Y, Wang Y, Li Y
Cutaneous and ocular toxicology 2022 Jun;41(2):179-186
Cutaneous and ocular toxicology 2022 Jun;41(2):179-186
Effects of dietary lycopene supplementation on intestinal morphology, antioxidant capability and inflammatory response in finishing pigs.
Liu A, Chen X, Huang Z, Chen D, Yu B, Chen H, He J, Yan H, Zheng P, Yu J, Luo Y
Animal biotechnology 2022 Jun;33(3):563-570
Animal biotechnology 2022 Jun;33(3):563-570
DEHP induces ferroptosis in testes via p38α-lipid ROS circulation and destroys the BTB integrity.
Yang L, Jiang L, Sun X, Li J, Wang N, Liu X, Yao X, Zhang C, Deng H, Wang S, Yang G
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113046
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113046
Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis.
Sun P, Zhang C, Huang Y, Yang J, Zhou F, Zeng J, Lin Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112975
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112975
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Zhang D, Ren Y, He Y, Chang R, Guo S, Ma S, Guan F, Yao M
Materials today. Bio 2022 Jun;15:100278
Materials today. Bio 2022 Jun;15:100278
Aryl-hydrocarbon receptor-interacting protein regulates tumorigenic and metastatic properties of colorectal cancer cells driving liver metastasis.
Solís-Fernández G, Montero-Calle A, Sánchez-Martínez M, Peláez-García A, Fernández-Aceñero MJ, Pallarés P, Alonso-Navarro M, Mendiola M, Hendrix J, Hardisson D, Bartolomé RA, Hofkens J, Rocha S, Barderas R
British journal of cancer 2022 Jun;126(11):1604-1615
British journal of cancer 2022 Jun;126(11):1604-1615
Atractyloside-A ameliorates spleen deficiency diarrhea by interfering with TLR4/MyD88/NF-κB signaling activation and regulating intestinal flora homeostasis.
Xu J, Liu C, Shi K, Sun X, Song C, Xu K, Liu Y
International immunopharmacology 2022 Jun;107:108679
International immunopharmacology 2022 Jun;107:108679
Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy.
Zhao Y, Zhang H, Zhang SL, Wei J, Zheng LL, Du JK, Zhu XY, Jiang L, Liu YJ
Annals of translational medicine 2022 Jun;10(11):630
Annals of translational medicine 2022 Jun;10(11):630
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Tian S, Wang J, Gao R, Wang J, Zhu W
Journal of animal science and biotechnology 2022 Jun 3;13(1):70
Journal of animal science and biotechnology 2022 Jun 3;13(1):70
Longitudinal 16S rRNA Sequencing Reveals Relationships among Alterations of Gut Microbiota and Nonalcoholic Fatty Liver Disease Progression in Mice.
Zhuge A, Li S, Lou P, Wu W, Wang K, Yuan Y, Xia J, Li B, Li L
Microbiology spectrum 2022 Jun 29;10(3):e0004722
Microbiology spectrum 2022 Jun 29;10(3):e0004722
Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia.
Wu DM, He M, Zhao YY, Deng SH, Liu T, Zhang T, Zhang F, Wang YY, Xu Y
Cell communication and signaling : CCS 2022 Jun 27;20(1):98
Cell communication and signaling : CCS 2022 Jun 27;20(1):98
Periodontitis may induce gut microbiota dysbiosis via salivary microbiota.
Bao J, Li L, Zhang Y, Wang M, Chen F, Ge S, Chen B, Yan F
International journal of oral science 2022 Jun 23;14(1):32
International journal of oral science 2022 Jun 23;14(1):32
Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.
Huang T, Che Q, Chen X, Chen D, Yu B, He J, Chen H, Yan H, Zheng P, Luo Y, Huang Z
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7576-7585
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7576-7585
Analysis by transcriptomics and metabolomics for the proliferation inhibition and dysfunction through redox imbalance-mediated DNA damage response and ferroptosis in male reproduction of mice and TM4 Sertoli cells exposed to PM(2.5).
Shi F, Zhang Z, Cui H, Wang J, Wang Y, Tang Y, Yang W, Zou P, Ling X, Han F, Liu J, Chen Q, Liu C, Cao J, Ao L
Ecotoxicology and environmental safety 2022 Jun 15;238:113569
Ecotoxicology and environmental safety 2022 Jun 15;238:113569
Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery.
Zhou J, Li M, Chen Q, Li X, Chen L, Dong Z, Zhu W, Yang Y, Liu Z, Chen Q
Nature communications 2022 Jun 14;13(1):3432
Nature communications 2022 Jun 14;13(1):3432
Oxidized PUFAs Increase Susceptibility of Mice to Salmonella Infection by Diminishing Host's Innate Immune Responses.
Wang Y, Liu J, Liu H, Liu L, Gao X, Tong Y, Song S, Yan C
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6407-6417
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6407-6417
Burn Injury-Induced Extracellular Vesicle Production and Characteristics.
Yang X, Chatterjee V, Zheng E, Reynolds A, Ma Y, Villalba N, Tran T, Jung M, Smith DJ, Wu MH, Yuan SY
Shock (Augusta, Ga.) 2022 Jun 1;57(6):228-242
Shock (Augusta, Ga.) 2022 Jun 1;57(6):228-242
Breast Cancer Stem Cells-derived Extracellular Vesicles Affect PPARG Expression by Delivering MicroRNA-197 in Breast Cancer Cells.
Li L, Xiong Y, Wang N, Zhu M, Gu Y
Clinical breast cancer 2022 Jul;22(5):478-490
Clinical breast cancer 2022 Jul;22(5):478-490
Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis.
Ding Q, Cao F, Lai S, Zhuge H, Chang K, Valencak TG, Liu J, Li S, Ren D
Food research international (Ottawa, Ont.) 2022 Jul;157:111259
Food research international (Ottawa, Ont.) 2022 Jul;157:111259
Protective role of casuarinin from Melastoma malabathricum against a mouse model of 5-fluorouracil-induced intestinal mucositis: Impact on inflammation and gut microbiota dysbiosis.
Chen KJ, Huang YL, Kuo LM, Chen YT, Hung CF, Hsieh PW
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154092
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154092
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Yu T, Liu Y, Xue J, Sun X, Zhu D, Ma L, Guo Y, Jin T, Cao H, Chen Y, Zhu T, Li X, Liang H, Du Z, Shan H
Cell death discovery 2022 Jul 9;8(1):312
Cell death discovery 2022 Jul 9;8(1):312
LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia.
Zhao C, Liu Y, Meng J, Wang X, Liu X, Li W, Zhou Q, Xiang J, Li N, Hou S
Investigative ophthalmology & visual science 2022 Jul 8;63(8):25
Investigative ophthalmology & visual science 2022 Jul 8;63(8):25
Human 2D Crypt Model for Assaying Intestinal Stem Cell Proliferation and Differentiation.
Wang Y, Sims CE, Allbritton NL
Analytical chemistry 2022 Jul 5;94(26):9345-9354
Analytical chemistry 2022 Jul 5;94(26):9345-9354
Neuroprotective Effects of Chlorogenic Acid in a Mouse Model of Intracerebral Hemorrhage Associated with Reduced Extracellular Matrix Metalloproteinase Inducer.
Liu Y, Wang F, Li Z, Mu Y, Yong VW, Xue M
Biomolecules 2022 Jul 22;12(8)
Biomolecules 2022 Jul 22;12(8)
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Tao W, Wang G, Pei X, Sun W, Wang M
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Delayed administration of nafamostat mesylate inhibits thrombin-mediated blood-spinal cord barrier breakdown during acute spinal cord injury in rats.
Zhao C, Zhou T, Zhao X, Pang Y, Li W, Fan B, Li M, Liu X, Ma L, Zhang J, Sun C, Shen W, Kong X, Yao X, Feng S
Journal of neuroinflammation 2022 Jul 16;19(1):189
Journal of neuroinflammation 2022 Jul 16;19(1):189
Effect of Houpo-Mahuang Decoction on aggravated asthma induced by cigarette smoke and the expression of TRPA1 and tight junctions in mice.
Sun YB, Ni Y, Fan XS, Zhou LP, Yue QF, Shang EX
Journal of ethnopharmacology 2022 Jul 15;293:115217
Journal of ethnopharmacology 2022 Jul 15;293:115217
Metformin protects against pericyte apoptosis and promotes neurogenesis through suppressing JNK p38 MAPK signalling activation in ischemia/reperfusion injury.
Liu C, Zhang D, Lu Z, Man J, Zhang Z, Fu X, Cui K, Wang J
Neuroscience letters 2022 Jul 13;783:136708
Neuroscience letters 2022 Jul 13;783:136708
Bryodulcosigenin a natural cucurbitane-type triterpenoid attenuates dextran sulfate sodium (DSS)-induced colitis in mice.
Li R, Chen C, Liu B, Shi W, Shimizu K, Zhang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153814
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153814
Radiocontrast agent and intraductal pressure promote the progression of post-ERCP pancreatitis by regulating inflammatory response, cellular apoptosis, and tight junction integrity.
Zhang D, Man X, Li L, Tang J, Liu F
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Jan;22(1):74-82
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Jan;22(1):74-82
A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury.
Wu C, Du M, Yu R, Cheng Y, Wu B, Fu J, Tan W, Zhou Q, Balawi E, Liao ZB
Free radical biology & medicine 2022 Jan;178:271-294
Free radical biology & medicine 2022 Jan;178:271-294
Enterococcus faecium HDRsEf1 inhibits Lipopolysaccharide-induced downregulation of zona occludens -1 expression via toll-like receptor 2/4-mediated c-Jun N-terminal kinase/activator protein-1 signalling pathways.
Liu L, Li Y, He Y, Wang Z, Zhao H, Jin X, Shi D, Wang X
Journal of applied microbiology 2022 Jan;132(1):605-617
Journal of applied microbiology 2022 Jan;132(1):605-617
Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis.
Li H, Zhang Y, Liu M, Fan C, Feng C, Lu Q, Xiang C, Lu H, Yang X, Wu B, Zou D, Tang W
Acta pharmaceutica Sinica. B 2022 Jan;12(1):228-245
Acta pharmaceutica Sinica. B 2022 Jan;12(1):228-245
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Yu X, Bai Y, Han B, Ju M, Tang T, Shen L, Li M, Yang L, Zhang Z, Hu G, Chao J, Zhang Y, Yao H
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Apple polyphenols improve intestinal barrier function by enhancing antioxidant capacity and suppressing inflammation in weaning piglets.
Guo Z, Chen X, Huang Z, Chen D, Yu J, Yan H, Chen H, He J, Zheng P, Luo Y, Yu B
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13747
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13747
Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue.
Song X, Yu Y, Leng Y, Ma L, Mu J, Wang Z, Xu Y, Zhu H, Qiu X, Li P, Li J, Wang D
Journal of tissue engineering 2022 Jan-Dec;13:20417314221125310
Journal of tissue engineering 2022 Jan-Dec;13:20417314221125310
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
Gong L, Xiao J, Yi J, Xiao J, Lu F, Liu X
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
Online Measurement System for Dynamic Flow Bioreactors to Study Barrier Integrity of hiPSC-Based Blood-Brain Barrier In Vitro Models.
Choi J, Mathew S, Oerter S, Appelt-Menzel A, Hansmann J, Schmitz T
Bioengineering (Basel, Switzerland) 2022 Jan 16;9(1)
Bioengineering (Basel, Switzerland) 2022 Jan 16;9(1)
De novo Lipogenesis in Astrocytes Promotes the Repair of Blood-Brain Barrier after Transient Cerebral Ischemia Through Interleukin-33.
Wei H, Zhen L, Wang S, Zhang Y, Wang K, Jia P, Zhang Y, Wu Z, Yang Q, Hou W, Lv J, Zhang P
Neuroscience 2022 Jan 15;481:85-98
Neuroscience 2022 Jan 15;481:85-98
Protective effects of polysaccharides from Atractylodes macrocephalae Koidz. against dextran sulfate sodium induced intestinal mucosal injury on mice.
Kai L, Zong X, Jiang Q, Lu Z, Wang F, Wang Y, Wang T, Jin M
International journal of biological macromolecules 2022 Jan 15;195:142-151
International journal of biological macromolecules 2022 Jan 15;195:142-151
Identifying distinct oxygen diffusivity through type I pneumocyte-like cell layers using microfluidic device.
Tung YC, Wang CK, Huang YK, Huang CK, Peng CC, Patra B, Chen HK, Tsao PN, Ling TY
Talanta 2022 Jan 1;236:122882
Talanta 2022 Jan 1;236:122882
Cordycepin, a major bioactive component of Cordyceps militaris, ameliorates diabetes-induced testicular damage through the Sirt1/Foxo3a pathway.
Huang T, Zhou Y, Lu X, Tang C, Ren C, Bao X, Deng Z, Cao X, Zou J, Zhang Q, Ma B
Andrologia 2022 Feb;54(1):e14294
Andrologia 2022 Feb;54(1):e14294
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2022 Feb;41(6):770-781
Oncogene 2022 Feb;41(6):770-781
Oral delivery of decanoic acid conjugated plant protein shell incorporating hybrid nanosystem leverage intestinal absorption of polyphenols.
Miao R, Jin F, Wang Z, Lu W, Liu J, Li X, Zhang RX
Biomaterials 2022 Feb;281:121373
Biomaterials 2022 Feb;281:121373
MicroRNA-582-5p regulates cell invasion in bladder cancer through targeting Forkhead Box G1.
Zhuang J, Hao J, Bu F, Yin H, Chen W, Guo H
Pathology, research and practice 2022 Feb;230:153752
Pathology, research and practice 2022 Feb;230:153752
Hyperglycemia induces corneal endothelial dysfunction through attenuating mitophagy.
Chen C, Zhou Q, Li Z, Duan H, Liu Y, Wan L, Wang H, Xie L
Experimental eye research 2022 Feb;215:108903
Experimental eye research 2022 Feb;215:108903
Connexin32 ameliorates epithelial-to-mesenchymal-transition in diabetic renal tubular via inhibiting NOX4.
Sun X, Xiao H, Li S, Chen R, Lin Z, Yang Y, Chen Z, Deng L, Huang H
Pharmacological research 2022 Feb;176:106084
Pharmacological research 2022 Feb;176:106084
CRH/CRHR1 modulates cerebrovascular endothelial cell permeability in association with S1PR2 and S1PR3 under oxidative stress.
Mu J, Que Y, Li X, Zhou F, Jin L, Li S, Zhu C
Vascular pharmacology 2022 Feb;142:106941
Vascular pharmacology 2022 Feb;142:106941
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Wang Q, Wang C, Abdullah, Tian W, Qiu Z, Song M, Cao Y, Xiao J
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Effects of Exopolysaccharides from Lactiplantibacillus plantarum JLAU103 on Intestinal Immune Response, Oxidative Stress, and Microbial Communities in Cyclophosphamide-Induced Immunosuppressed Mice.
Wang J, Li M, Gao Y, Li H, Fang L, Liu C, Liu X, Min W
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2197-2210
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2197-2210
Akkermansia muciniphila Ameliorates Acetaminophen-Induced Liver Injury by Regulating Gut Microbial Composition and Metabolism.
Xia J, Lv L, Liu B, Wang S, Zhang S, Wu Z, Yang L, Bian X, Wang Q, Wang K, Zhuge A, Li S, Yan R, Jiang H, Xu K, Li L
Microbiology spectrum 2022 Feb 23;10(1):e0159621
Microbiology spectrum 2022 Feb 23;10(1):e0159621
LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland.
Ma R, Gong D, You H, Xu C, Lu Y, Bergers G, Werb Z, Klein OD, Petritsch CK, Lu P
Cell reports 2022 Feb 15;38(7):110375
Cell reports 2022 Feb 15;38(7):110375
LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice.
Wang S, Qian Z, Ge X, Li C, Xue M, Liang K, Ma R, Ouyang L, Zheng L, Jing J, Cao S, Zhang Y, Yang Y, Chen Y, Ma J, Yao B
Cellular and molecular life sciences : CMLS 2022 Feb 1;79(2):114
Cellular and molecular life sciences : CMLS 2022 Feb 1;79(2):114
A Pilot Application of an iTRAQ-Based Proteomics Screen Estimates the Effects of Cigarette Smokers' Serum on RPE Cells With AMD High-Risk Alleles.
Cai B, Zhang Z, Sun S, Lin T, Ke Y, Li Z, Yang J, Li X
Translational vision science & technology 2022 Feb 1;11(2):15
Translational vision science & technology 2022 Feb 1;11(2):15
Effects of dietary dihydromyricetin supplementation on intestinal barrier and humoral immunity in growing-finishing pigs.
Wei C, Chen X, Chen D, He J, Zheng P, Chen H, Yan H, Yu B, Luo Y, Huang Z
Animal biotechnology 2022 Dec;33(7):1398-1406
Animal biotechnology 2022 Dec;33(7):1398-1406
Hesperidin partly ameliorates the decabromodiphenyl ether-induced reproductive toxicity in pubertal mice.
Li S, Che S, Chen S, Ruan Z, Zhang L
Environmental science and pollution research international 2022 Dec;29(60):90391-90403
Environmental science and pollution research international 2022 Dec;29(60):90391-90403
Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.
Guo W, Wang X, Liu F, Chen S, Wang S, Zhang Q, Yuan L, Du S
Molecular medicine reports 2022 Dec;26(6)
Molecular medicine reports 2022 Dec;26(6)
Polysaccharide ORP-1 isolated from Oudemansiella raphanipes ameliorates age-associated intestinal epithelial barrier dysfunction in Caco-2 cells monolayer.
Pan WJ, Shi LL, Ren YR, Yao CY, Lu YM, Chen Y
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt A):112038
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt A):112038
Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiation.
Xia S, Chen L, Li Z, Li Y, Zhou Y, Sun S, Su Y, Xu X, Shao J, Zhang Z, Kong D, Zhang F, Zheng S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154460
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154460
Dahuang Mudan decoction repairs intestinal barrier in chronic colitic mice by regulating the function of ILC3.
Huang S, Wang X, Xie X, Su Y, Pan Z, Li Y, Liang J, Zhang M, Pan S, Xu B, Li L, Chen J, Luo X, Zhou L
Journal of ethnopharmacology 2022 Dec 5;299:115652
Journal of ethnopharmacology 2022 Dec 5;299:115652
Glutathione Protects against Paraquat-Induced Oxidative Stress by Regulating Intestinal Barrier, Antioxidant Capacity, and CAR Signaling Pathway in Weaned Piglets.
Xiang X, Wang H, Zhou W, Wang C, Guan P, Xu G, Zhao Q, He L, Yin Y, Li T
Nutrients 2022 Dec 30;15(1)
Nutrients 2022 Dec 30;15(1)
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Yan J, Zhang Y, Wang L, Li Z, Tang S, Wang Y, Gu N, Sun X, Li L
Journal of neuroinflammation 2022 Dec 3;19(1):289
Journal of neuroinflammation 2022 Dec 3;19(1):289
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Sun Y, Li H, Liu L, Bai X, Wu L, Shan J, Sun X, Wang Q, Guo Y
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
Effect of ginsenoside compound K on alleviating colitis via modulating gut microbiota.
Wang L, Shao L, Chen MY, Wang L, Zhang W, Tan FB, Huang WH
Chinese medicine 2022 Dec 28;17(1):146
Chinese medicine 2022 Dec 28;17(1):146
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Wu Y, Bao W, Ren J, Li C, Chen M, Zhang D, Zhu A
Genes 2022 Dec 27;14(1)
Genes 2022 Dec 27;14(1)
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo.
Xia X, Lin H, Luo F, Wu X, Zhu L, Chen S, Luo H, Ye F, Peng X, Zhang Y, Yang G, Lin Q
Journal of agricultural and food chemistry 2022 Dec 21;70(50):15747-15762
Journal of agricultural and food chemistry 2022 Dec 21;70(50):15747-15762
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Wang W, Jiang S, Xu C, Tang L, Liang Y, Zhao Y, Zhu G
Microbiology spectrum 2022 Dec 21;10(6):e0324222
Microbiology spectrum 2022 Dec 21;10(6):e0324222
Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury.
Huang B, Gui M, Ni Z, He Y, Zhao J, Peng J, Lin J
Microbiology spectrum 2022 Dec 21;10(6):e0167722
Microbiology spectrum 2022 Dec 21;10(6):e0167722
Exploration of the mechanisms underlying the beneficial effect of Luo Tong formula on retinal function in diabetic rats via the "gut microbiota-inflammation-retina" axis.
Di S, Yao C, Qiao L, Li X, Pang B, Lin J, Wang J, Li M, Tong X
Chinese medicine 2022 Dec 2;17(1):133
Chinese medicine 2022 Dec 2;17(1):133
Intermittent Fasting Alleviates Risk Markers in a Murine Model of Ulcerative Colitis by Modulating the Gut Microbiome and Metabolome.
Wu J, Man D, Shi D, Wu W, Wang S, Wang K, Li Y, Yang L, Bian X, Wang Q, Li L
Nutrients 2022 Dec 14;14(24)
Nutrients 2022 Dec 14;14(24)
The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response.
Chamseddine D, Mahmud SA, Westfall AK, Castoe TA, Berg RE, Pellegrino MW
Cell reports 2022 Dec 13;41(11):111789
Cell reports 2022 Dec 13;41(11):111789
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Zhao N, Yang Y, Chen C, Jing T, Hu Y, Xu H, Wang S, He Y, Liu E, Cui J
Food & function 2022 Dec 13;13(24):12814-12826
Food & function 2022 Dec 13;13(24):12814-12826
Effects of chitosan oligosaccharides (COS) and FMT from COS-dosed mice on intestinal barrier function and cell apoptosis.
Na K, Wei J, Zhang L, Fang Y, Li X, Lu S, Guo X
Carbohydrate polymers 2022 Dec 1;297:120043
Carbohydrate polymers 2022 Dec 1;297:120043
Microglia Regulate Blood-Brain Barrier Integrity via MiR-126a-5p/MMP9 Axis during Inflammatory Demyelination.
Yu Z, Fang X, Liu W, Sun R, Zhou J, Pu Y, Zhao M, Sun D, Xiang Z, Liu P, Ding Y, Cao L, He C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105442
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105442
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Hou Z, Ding Q, Li Y, Zhao Z, Yan F, Li Y, Wang X, Xu J, Chen W, Wu G, Ruan X, Zhao L
EBioMedicine 2022 Aug;82:104181
EBioMedicine 2022 Aug;82:104181
Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis.
Luo Y, Zhang Y, Han X, Yuan Y, Zhou Y, Gao Y, Yu H, Zhang J, Shi Y, Duan Y, Zhao X, Yan S, Hao H, Dai C, Zhao S, Shi J, Li W, Zhang S, Xu W, Fang N, Gong Y, Li Y
EBioMedicine 2022 Aug;82:104087
EBioMedicine 2022 Aug;82:104087
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Ge X, He Z, Cao C, Xue T, Jing J, Ma R, Zhao W, Liu L, Jueraitetibaike K, Ma J, Feng Y, Qian Z, Zou Z, Chen L, Fu C, Song N, Yao B
Redox biology 2022 Aug;54:102380
Redox biology 2022 Aug;54:102380
Pyroptosis participates in PM(2.5)-induced air-blood barrier dysfunction.
Jia R, Wei M, Zhang X, Du R, Sun W, Wang L, Song L
Environmental science and pollution research international 2022 Aug;29(40):60987-60997
Environmental science and pollution research international 2022 Aug;29(40):60987-60997
Chitosan-modified Phellinus igniarius polysaccharide PLGA nanoparticles ameliorated inflammatory bowel disease.
Bai X, Feng Z, Peng S, Zhu T, Jiao L, Mao N, Gu P, Liu Z, Yang Y, Wang D
Biomaterials advances 2022 Aug;139:213002
Biomaterials advances 2022 Aug;139:213002
Comparative Effects of Allulose, Fructose, and Glucose on the Small Intestine.
Suzuki T, Sato Y, Kadoya S, Takahashi T, Otomo M, Kobayashi H, Aoki K, Kantake M, Sugiyama M, Ferraris RP
Nutrients 2022 Aug 7;14(15)
Nutrients 2022 Aug 7;14(15)
Tollip Orchestrates Macrophage Polarization to Alleviate Intestinal Mucosal Inflammation.
Liu X, Ren X, Zhou L, Liu K, Deng L, Qing Q, Li J, Zhi F, Li M
Journal of Crohn's & colitis 2022 Aug 4;16(7):1151-1167
Journal of Crohn's & colitis 2022 Aug 4;16(7):1151-1167
Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.
Liu Z, Jiang Z, Zhang Z, Liu T, Fan Y, Liu T, Peng N
Microbiology spectrum 2022 Aug 31;10(4):e0064122
Microbiology spectrum 2022 Aug 31;10(4):e0064122
Protective effect of surface-layer proteins from four Lactobacillus strains on tumor necrosis factor-α-induced intestinal barrier dysfunction.
Zhang J, Li Q, Wu L, Xu S, Lu R
Journal of the science of food and agriculture 2022 Aug 30;102(11):4446-4453
Journal of the science of food and agriculture 2022 Aug 30;102(11):4446-4453
Neohesperidin Dihydrochalcone Ameliorates High-Fat Diet-Induced Glycolipid Metabolism Disorder in Rats.
Xiao Y, Su D, Hu X, Yang G, Shan Y
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9421-9431
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9421-9431
Wumei pills attenuates 5-fluorouracil-induced intestinal mucositis through Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB pathway and microbiota regulation.
Lu DX, Liu F, Wu H, Liu HX, Chen BY, Yan J, Lu Y, Sun ZG
World journal of gastroenterology 2022 Aug 28;28(32):4574-4599
World journal of gastroenterology 2022 Aug 28;28(32):4574-4599
Stigmasterol attenuates hepatic steatosis in rats by strengthening the intestinal barrier and improving bile acid metabolism.
Zhang Y, Gu Y, Jiang J, Cui X, Cheng S, Liu L, Huang Z, Liao R, Zhao P, Yu J, Wang J, Jia Y, Jin W, Zhou F
NPJ science of food 2022 Aug 27;6(1):38
NPJ science of food 2022 Aug 27;6(1):38
Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood-brain barrier disruption.
Hu H, Yang X, He Y, Duan C, Sun N
Journal of neuroinflammation 2022 Aug 24;19(1):208
Journal of neuroinflammation 2022 Aug 24;19(1):208
[Diethylhexyl phthalate induces anxiety-like behavior and learning and memory impairment in mice probably by damaging blood-brain barrier].
Li F, Zhu Y, Sun X, Hu H, Zhou M, Bai Y, Hu H
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 Aug 20;42(8):1237-1243
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 Aug 20;42(8):1237-1243
Ascorbic acid induces salivary gland function through TET2/acetylcholine receptor signaling in aging SAMP1/Klotho (-/-) mice.
Toan NK, Kim SA, Ahn SG
Aging 2022 Aug 11;14(15):6028-6046
Aging 2022 Aug 11;14(15):6028-6046
Urolithin A attenuates arsenic-induced gut barrier dysfunction.
Ghosh S, Banerjee M, Haribabu B, Jala VR
Archives of toxicology 2022 Apr;96(4):987-1007
Archives of toxicology 2022 Apr;96(4):987-1007
Curcumin Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice Through Regulating Gut Microbiota.
Guo X, Xu Y, Geng R, Qiu J, He X
Molecular nutrition & food research 2022 Apr;66(8):e2100943
Molecular nutrition & food research 2022 Apr;66(8):e2100943
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.
Li HL, Wei YY, Li XH, Zhang SS, Zhang RT, Li JH, Ma BW, Shao SB, Lv ZW, Ruan H, Zhou HG, Yang C
Acta pharmacologica Sinica 2022 Apr;43(4):919-932
Acta pharmacologica Sinica 2022 Apr;43(4):919-932
Dietary ferulic acid supplementation improves intestinal antioxidant capacity and intestinal barrier function in weaned piglets.
Chen X, Wang Y, Chen D, Yu B, Huang Z
Animal biotechnology 2022 Apr;33(2):356-361
Animal biotechnology 2022 Apr;33(2):356-361
Mesencephalic astrocyte-derived neurotrophic factor restores blood-brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway.
Han D, Li F, Zhang H, Ji C, Shu Q, Wang C, Ni H, Zhu Y, Wang S
Journal of drug targeting 2022 Apr;30(4):430-441
Journal of drug targeting 2022 Apr;30(4):430-441
Gelsolin impairs barrier function in pancreatic ductal epithelial cells by actin filament depolymerization in hypertriglyceridemia-induced pancreatitis in vitro.
Yang HY, Liang ZH, Xie JL, Wu Q, Qin YY, Zhang SY, Tang GD
Experimental and therapeutic medicine 2022 Apr;23(4):290
Experimental and therapeutic medicine 2022 Apr;23(4):290
Interfering with alternatively activated macrophages by CSF-1R inhibition exerts therapeutic capacity on allergic airway inflammation.
Xiang C, Fan C, Lu Q, Liu M, Lu H, Feng C, Wu Y, Wu B, Li H, Tang W
Biochemical pharmacology 2022 Apr;198:114952
Biochemical pharmacology 2022 Apr;198:114952
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Zhan L, Pu J, Zheng J, Hang S, Pang L, Dai M, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
Late-onset hearing loss case associated with a heterozygous truncating variant of DIAPH1.
Kim BJ, Miyoshi T, Chaudhry T, Friedman TB, Choi BY, Ueyama T
Clinical genetics 2022 Apr;101(4):466-471
Clinical genetics 2022 Apr;101(4):466-471
Industrially Produced Rice Protein Ameliorates Dextran Sulfate Sodium-Induced Colitis via Protecting the Intestinal Barrier, Mitigating Oxidative Stress, and Regulating Gut Microbiota.
Huang Z, Yang W, Wang X, Guo F, Cheng Y, Cao L, Zhu W, Sun Y, Xiong H
Journal of agricultural and food chemistry 2022 Apr 27;70(16):4952-4965
Journal of agricultural and food chemistry 2022 Apr 27;70(16):4952-4965
Anemone chinensis Bunge aqueous enema alleviates dextran sulfate sodium-induced colitis via inhibition of inflammation and regulation of the colonic mucosal microbiota.
Dong L, Fan X, Li Q, Li J, Chen G, Yang D, Li Y, Zhao L, Yin H, Wang X, Liu X, Zhao Z, Lin S
Journal of ethnopharmacology 2022 Apr 24;288:114916
Journal of ethnopharmacology 2022 Apr 24;288:114916
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Song L, Wu T, Zhang L, Wan J, Ruan Z
Food & function 2022 Apr 20;13(8):4562-4575
Food & function 2022 Apr 20;13(8):4562-4575
Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.
Yan S, Chen J, Zhu L, Guo T, Qin D, Hu Z, Han S, Wang J, Matias FB, Wen L, Luo F, Lin Q
Food & function 2022 Apr 20;13(8):4486-4501
Food & function 2022 Apr 20;13(8):4486-4501
Comparison of the effects of different calorie amounts of enteral nutrition in hypercatabolism associated with ghrelin-POMC in endotoxemic rats.
Duan J, Cheng M, Xu Y, Tang S, Li X, Chen Y, Lu H, Gao T, Yu W
Nutrition & metabolism 2022 Apr 15;19(1):28
Nutrition & metabolism 2022 Apr 15;19(1):28
Sertoli cell and spermatogonial development in pigs.
Zheng Y, Gao Q, Li T, Liu R, Cheng Z, Guo M, Xiao J, Wu D, Zeng W
Journal of animal science and biotechnology 2022 Apr 11;13(1):45
Journal of animal science and biotechnology 2022 Apr 11;13(1):45
Ubiquitin-Specific Protease 25 Aggravates Acute Pancreatitis and Acute Pancreatitis-Related Multiple Organ Injury by Destroying Tight Junctions Through Activation of The STAT3 Pathway.
Liu Z, Qi M, Tian S, Yang Q, Liu J, Wang S, Ji M, Yu R, Zeng S, Li J, Wei Y, Dong W
Frontiers in cell and developmental biology 2021;9:806850
Frontiers in cell and developmental biology 2021;9:806850
Cathelicidin-WA Protects Against LPS-Induced Gut Damage Through Enhancing Survival and Function of Intestinal Stem Cells.
Wang S, Kai L, Zhu L, Xu B, Chen N, Valencak TG, Wang Y, Shan T
Frontiers in cell and developmental biology 2021;9:685363
Frontiers in cell and developmental biology 2021;9:685363
P16 (I NK 4a) Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.
Zhou J, Hou C, Chen H, Qin Z, Miao Z, Zhao J, Wang Q, Cui M, Xie C, Wang R, Li Q, Zuo G, Miao D, Jin J
Frontiers in cell and developmental biology 2021;9:671564
Frontiers in cell and developmental biology 2021;9:671564
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Chen L, Huang X, Wang L, Wang C, Tang X, Gu M, Jing J, Ma R, Ge X, Yao B
Frontiers in cell and developmental biology 2021;9:648578
Frontiers in cell and developmental biology 2021;9:648578
Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice.
Li Y, Tao Y, Xu J, He Y, Zhang W, Jiang Z, He Y, Liu H, Chen M, Zhang W, Xing Z
Frontiers in medicine 2021;8:732039
Frontiers in medicine 2021;8:732039
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Gu L, Ren F, Fang X, Yuan L, Liu G, Wang S
Frontiers in medicine 2021;8:660614
Frontiers in medicine 2021;8:660614
Bovine Lactoferrin Protects Dextran Sulfate Sodium Salt Mice Against Inflammation and Impairment of Colonic Epithelial Barrier by Regulating Gut Microbial Structure and Metabolites.
Wang S, Zhou J, Xiao D, Shu G, Gu L
Frontiers in nutrition 2021;8:660598
Frontiers in nutrition 2021;8:660598
Effects of Guava (Psidium guajava L.) Leaf Extract on the Metabolomics of Serum and Feces in Weaned Piglets Challenged by Escherichia coli.
Wang D, Zhou L, Zhou H, Hou G
Frontiers in veterinary science 2021;8:656179
Frontiers in veterinary science 2021;8:656179
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via Activation of Peribiliary Glands through the Wnt Pathway.
Tian X, Cao H, Wu L, Zheng W, Yuan M, Li X, Song H, Shen Z
Stem cells international 2021;2021:9935370
Stem cells international 2021;2021:9935370
Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota.
Zhou X, Lu J, Wei K, Wei J, Tian P, Yue M, Wang Y, Hong D, Li F, Wang B, Chen T, Fang X
Oxidative medicine and cellular longevity 2021;2021:9424582
Oxidative medicine and cellular longevity 2021;2021:9424582
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
Zou W, Qian C, Zhang S, Wan X, Wei Z, Li X, Wu Y, Chen W, Wang A, Zhao Y, Lu Y
Oxidative medicine and cellular longevity 2021;2021:7037786
Oxidative medicine and cellular longevity 2021;2021:7037786
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1(-/-) Mice.
Zhang Z, Zhang L, Zhang Q, Liu B, Li F, Xin Y, Duan Z
Oxidative medicine and cellular longevity 2021;2021:6620873
Oxidative medicine and cellular longevity 2021;2021:6620873
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
Wan Y, Song M, Xie X, Chen Z, Gao Z, Wu X, Huang R, Chen M
Mediators of inflammation 2021;2021:5522291
Mediators of inflammation 2021;2021:5522291
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Yang W, Xu X, Xu M, Zhou J, Xi Z, Guo H, Ming J, Huang T
OncoTargets and therapy 2021;14:2339-2348
OncoTargets and therapy 2021;14:2339-2348
Overexpression of 15-Hydroxyprostaglandin Dehydrogenase Inhibits A549 Lung Adenocarcinoma Cell Growth via Inducing Cell Cycle Arrest and Inhibiting Epithelial-Mesenchymal Transition.
Wang W, Yang C, Deng H
Cancer management and research 2021;13:8887-8900
Cancer management and research 2021;13:8887-8900
Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.
Li T, Tang Z, Li C, Liu X, Cheng L, Yang Z, Zhu X, Liu W, Huang Y
Frontiers in pharmacology 2021;12:804615
Frontiers in pharmacology 2021;12:804615
Evaluation of the Anti-Aging Effects of a Probiotic Combination Isolated From Centenarians in a SAMP8 Mouse Model.
Fang X, Yue M, Wei J, Wang Y, Hong D, Wang B, Zhou X, Chen T
Frontiers in immunology 2021;12:792746
Frontiers in immunology 2021;12:792746
Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury.
Gong S, Ma H, Zheng F, Huang J, Zhang Y, Yu B, Li F, Kou J
Frontiers in pharmacology 2021;12:777680
Frontiers in pharmacology 2021;12:777680
Integrated Analysis of the Cecal Microbiome and Plasma Metabolomics to Explore NaoMaiTong and Its Potential Role in Changing the Intestinal Flora and Their Metabolites in Ischemic Stroke.
Lin H, Chen S, Shen L, Hu T, Cai J, Zhan S, Liang J, Huang M, Xian M, Wang S
Frontiers in pharmacology 2021;12:773722
Frontiers in pharmacology 2021;12:773722
Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma.
Qiao Y, Chen Y, Tan C, Sun X, Chen X, Chen J
Frontiers in genetics 2021;12:764509
Frontiers in genetics 2021;12:764509
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
Ren J, Yan D, Wang Y, Zhang J, Li M, Xiong W, Jing X, Li P, Zhao W, Xiong X, Wu M, Zhong G
Frontiers in immunology 2021;12:760999
Frontiers in immunology 2021;12:760999
The Panda-Derived Lactobacillus plantarum G201683 Alleviates the Inflammatory Response in DSS-Induced Panda Microbiota-Associated Mice.
Zhou Y, Duan L, Zeng Y, Niu L, Pu Y, Jacobs JP, Chang C, Wang J, Khalique A, Pan K, Fang J, Jing B, Zeng D, Ni X
Frontiers in immunology 2021;12:747045
Frontiers in immunology 2021;12:747045
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Shi A, Li T, Zheng Y, Song Y, Wang H, Wang N, Dong L, Shi H
Frontiers in pharmacology 2021;12:693048
Frontiers in pharmacology 2021;12:693048
Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis.
Qu Y, Li X, Xu F, Zhao S, Wu X, Wang Y, Xie J
Frontiers in immunology 2021;12:679897
Frontiers in immunology 2021;12:679897
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
He Y, Chen J, Zhang Q, Zhang J, Wang L, Chen X, Molenaar AJ, Sun X
Frontiers in plant science 2021;12:673774
Frontiers in plant science 2021;12:673774
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Ye R, Wang C, Sun P, Bai S, Zhao L
Frontiers in pharmacology 2021;12:669403
Frontiers in pharmacology 2021;12:669403
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Qi R, Zhang Z, Wang J, Qiu X, Wang Q, Yang F, Huang J, Liu Z
Frontiers in microbiology 2021;12:623673
Frontiers in microbiology 2021;12:623673
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
Chen L, Zhong X, Cao W, Mao M, Li W, Yang H, Li M, Shi M, Zhang Y, Deng Y, Zu X, Liu J
Frontiers in immunology 2021;12:609319
Frontiers in immunology 2021;12:609319
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization.
Chen C, Yuan W, Zhou Q, Shao B, Guo Y, Wang W, Yang S, Guo Y, Zhao L, Dang Q, Yang X, Wang G, Kang Q, Ji Z, Liu J, Sun Z
Theranostics 2021;11(9):4298-4315
Theranostics 2021;11(9):4298-4315
Susceptibility of Human Airway Tissue Models Derived From Different Anatomical Sites to Bordetella pertussis and Its Virulence Factor Adenylate Cyclase Toxin.
Sivarajan R, Kessie DK, Oberwinkler H, Pallmann N, Walles T, Scherzad A, Hackenberg S, Steinke M
Frontiers in cellular and infection microbiology 2021;11:797491
Frontiers in cellular and infection microbiology 2021;11:797491
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Qin Q, Chen Y, Li Y, Wei J, Zhou X, Le F, Hu H, Chen T
Frontiers in cellular and infection microbiology 2021;11:719542
Frontiers in cellular and infection microbiology 2021;11:719542
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Chen G, Yang Z, Wen D, Guo J, Xiong Q, Li P, Zhao L, Wang J, Wu C, Dong L
Immunity, inflammation and disease 2021 Sep;9(3):959-970
Immunity, inflammation and disease 2021 Sep;9(3):959-970
Neutrophil extracellular traps induce thrombogenicity in severe carotid stenosis.
Zhang S, Guo M, Liu Q, Liu J, Cui Y
Immunity, inflammation and disease 2021 Sep;9(3):1025-1036
Immunity, inflammation and disease 2021 Sep;9(3):1025-1036
The important roles and molecular mechanisms of annexin A(2) autoantibody in children with nephrotic syndrome.
Ye Q, Zhang Y, Zhuang J, Bi Y, Xu H, Shen Q, Liu J, Fu H, Wang J, Feng C, Tang X, Liu F, Gu W, Zhao F, Zhang J, Qin Y, Shang S, Shen H, Chen X, Shen H, Liu A, Xia Y, Lu Z, Shu Q, Mao J
Annals of translational medicine 2021 Sep;9(18):1452
Annals of translational medicine 2021 Sep;9(18):1452
Enteromorpha polysaccharide-zinc replacing prophylactic antibiotics contributes to improving gut health of weaned piglets.
Xie C, Zhang Y, Niu K, Liang X, Wang H, Shan J, Wu X
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2021 Sep;7(3):641-649
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2021 Sep;7(3):641-649
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Mondal A, Saha P, Bose D, Chatterjee S, Seth RK, Xiao S, Porter DE, Brooks BW, Scott GI, Nagarkatti M, Nagarkatti P, Chatterjee S
Toxicology 2021 Sep;461:152901
Toxicology 2021 Sep;461:152901
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Magnetically-propelled fecal surrogates for modeling the impact of solid-induced shear forces on primary colonic epithelial cells.
Hinman SS, Huling J, Wang Y, Wang H, Bretherton RC, DeForest CA, Allbritton NL
Biomaterials 2021 Sep;276:121059
Biomaterials 2021 Sep;276:121059
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 Sep;27(9):1048-1063
CNS neuroscience & therapeutics 2021 Sep;27(9):1048-1063
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Liu C, Cheng Y, Guo Y, Qian H
Brain research bulletin 2021 Sep;174:184-193
Brain research bulletin 2021 Sep;174:184-193
Mfsd2a overexpression alleviates vascular dysfunction in diabetic retinopathy.
Zhang CL, Wang HL, Li PC, Hong CD, Chen AQ, Qiu YM, Zeng AP, Zhou YF, Hu B, Li YN
Pharmacological research 2021 Sep;171:105755
Pharmacological research 2021 Sep;171:105755
Treatment of early brain injury after subarachnoid hemorrhage in the rat model by inhibiting p53-induced ferroptosis.
Kuang H, Wang T, Liu L, Tang C, Li T, Liu M, Wang T, Zhong W, Wang Y
Neuroscience letters 2021 Sep 25;762:136134
Neuroscience letters 2021 Sep 25;762:136134
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Chen S, Li Y, Chu B, Yuan L, Liu N, Zhu Y, Wang J
Microorganisms 2021 Sep 17;9(9)
Microorganisms 2021 Sep 17;9(9)
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Hu S, Li S, Liu Y, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
Xun W, Fu Q, Shi L, Cao T, Jiang H, Ma Z
International immunopharmacology 2021 Oct;99:107989
International immunopharmacology 2021 Oct;99:107989
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Zhong G, Zhang J, Guo Y, Wang Y, Wu M, Ren J, Li Y, Zhang X, Zhou B, Zhao W, Lou Y, Wang H, Ye J
International immunopharmacology 2021 Oct;99:107980
International immunopharmacology 2021 Oct;99:107980
Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure.
Lesko AC, Keller R, Chen P, Sutherland A
Developmental biology 2021 Oct;478:59-75
Developmental biology 2021 Oct;478:59-75
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
Yu W, Jin H, Sun W, Nan D, Deng J, Jia J, Yu Z, Huang Y
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Xu SY, Bian HJ, Shu S, Xia SN, Gu Y, Zhang MJ, Xu Y, Cao X
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Li L, Cheng SQ, Guo W, Cai ZY, Sun YQ, Huang XX, Yang J, Ji J, Chen YY, Dong YF, Cheng H, Sun XL
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Regulation of blood-brain barrier permeability by Salvinorin A via alleviating endoplasmic reticulum stress in brain endothelial cell after ischemia stroke.
Xin J, Ma X, Chen W, Zhou W, Dong H, Wang Z, Ji F
Neurochemistry international 2021 Oct;149:105093
Neurochemistry international 2021 Oct;149:105093
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Chen G, Zeng H, Li X, Liu J, Li Z, Xu R, Ma Y, Liu C, Xue B
Cell death & disease 2021 Oct 30;12(11):1034
Cell death & disease 2021 Oct 30;12(11):1034
Improved epithelial cell-cell adhesion using molecular mobility of supramolecular surfaces.
Mikami R, Arisaka Y, Hakariya M, Iwata T, Yui N
Biomaterials science 2021 Oct 26;9(21):7151-7158
Biomaterials science 2021 Oct 26;9(21):7151-7158
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Liao M, Zhang Y, Qiu Y, Wu Z, Zhong Z, Zeng X, Zeng Y, Xiong L, Wen Y, Liu R
Food & function 2021 Oct 19;12(20):9844-9854
Food & function 2021 Oct 19;12(20):9844-9854
Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply.
Du K, Li S, Li C, Li P, Miao C, Luo T, Qiu B, Ding W
Acta biomaterialia 2021 Oct 15;134:228-239
Acta biomaterialia 2021 Oct 15;134:228-239
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653
Chemico-biological interactions 2021 Oct 1;348:109653
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
Lu YW, Hao RJ, Wei YY, Yu GR
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Song M, Zhang S, Tao Z, Li J, Shi Y, Xiong Y, Zhang W, Liu C, Chen S
Biomaterials 2021 Nov;278:121183
Biomaterials 2021 Nov;278:121183
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Zhu H, Lu C, Gao F, Qian Z, Yin Y, Kan S, Chen D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Seaweed polysaccharide mitigates intestinal barrier dysfunction induced by enterotoxigenic Escherichia coli through NF-κB pathway suppression in porcine intestinal epithelial cells.
Guo X, Chen J, Yang J, He Q, Luo B, Lu Y, Zou T, Wang Z, You J
Journal of animal physiology and animal nutrition 2021 Nov;105(6):1063-1074
Journal of animal physiology and animal nutrition 2021 Nov;105(6):1063-1074
Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting the intestinal barrier, mitigating oxidative stress and regulating the gut microbiota.
Wu T, Wang X, Xiong H, Deng Z, Peng X, Xiao L, Jiang L, Sun Y
Food & function 2021 Nov 29;12(23):11760-11776
Food & function 2021 Nov 29;12(23):11760-11776
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Deng S, Wu D, Li L, Li J, Xu Y
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Hu S, Chen Y, Zhao S, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Wei R, Liu X, Wang Y, Dong J, Wu F, Mackenzie GG, Su Z
Food & function 2021 Nov 15;12(22):11671-11685
Food & function 2021 Nov 15;12(22):11671-11685
Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation.
Guo F, Tsao R, Li C, Wang X, Zhang H, Jiang L, Sun Y, Xiong H
Foods (Basel, Switzerland) 2021 Nov 11;10(11)
Foods (Basel, Switzerland) 2021 Nov 11;10(11)
Neuroprotection of minocycline by inhibition of extracellular matrix metalloproteinase inducer expression following intracerebral hemorrhage in mice.
Liu Y, Li Z, Khan S, Zhang R, Wei R, Zhang Y, Xue M, Yong VW
Neuroscience letters 2021 Nov 1;764:136297
Neuroscience letters 2021 Nov 1;764:136297
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Kong L, Ma Y, Wang Z, Liu N, Ma G, Liu C, Shi R, Du G
International immunopharmacology 2021 May;94:107507
International immunopharmacology 2021 May;94:107507
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Wang G, Hu YX, He MY, Xie YH, Su W, Long D, Zhao R, Wang J, Dai C, Li H, Si ZP, Cheng X, Li RM, Li Z, Yang X
The American journal of pathology 2021 May;191(5):838-856
The American journal of pathology 2021 May;191(5):838-856
Interleukin-9 promotes intestinal barrier injury of sepsis: a translational research.
Sun JK, Zhou J, Sun XP, Shen X, Zhu DM, Wang X, Zhou SM, Mu XW
Journal of intensive care 2021 May 3;9(1):37
Journal of intensive care 2021 May 3;9(1):37
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Xue S, Tang H, Zhao G, Fang C, Shen Y, Yan D, Yuan Y, Fu W, Shi Z, Tang X, Guo D
Free radical biology & medicine 2021 May 1;167:181-192
Free radical biology & medicine 2021 May 1;167:181-192
Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.
Li L, Zhou C, Li T, Xiao W, Yu M, Yang H
Annals of translational medicine 2021 Mar;9(5):365
Annals of translational medicine 2021 Mar;9(5):365
Naringenin attenuates experimental autoimmune encephalomyelitis by protecting the intact of blood-brain barrier and controlling inflammatory cell migration.
Niu X, Sang H, Wang J
The Journal of nutritional biochemistry 2021 Mar;89:108560
The Journal of nutritional biochemistry 2021 Mar;89:108560
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Fan L, Peng Y, Wang J, Ma P, Zhao L, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
Liu CD, Liu NN, Zhang S, Ma GD, Yang HG, Kong LL, Du GH
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
l-Arabinose Attenuates Gliadin-Induced Food Allergy via Regulation of Th1/Th2 Balance and Upregulation of Regulatory T Cells in Mice.
Wang Y, Sun J, Xue L, Liu J, Nie C, Fan M, Qian H, Zhang D, Ying H, Li Y, Wang L
Journal of agricultural and food chemistry 2021 Mar 31;69(12):3638-3646
Journal of agricultural and food chemistry 2021 Mar 31;69(12):3638-3646
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
Zhu S, Liang J, Zhu F, Zhang X, Xu M, Zhao K, Zeng L, Xu K
Bioscience reports 2021 Mar 26;41(3)
Bioscience reports 2021 Mar 26;41(3)
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Wang W, Zhai D, Bai Y, Xue K, Deng L, Ma L, Du T, Ye Z, Qu D, Xiang A, Chen G, Zhao Y, Wang L, Lu Z
Cell death discovery 2021 Mar 23;7(1):58
Cell death discovery 2021 Mar 23;7(1):58
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Fu J, Wang T, Xiao X, Cheng Y, Wang F, Jin M, Wang Y, Zong X
Cells 2021 Mar 2;10(3)
Cells 2021 Mar 2;10(3)
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice.
Esposito G, Pesce M, Seguella L, Lu J, Corpetti C, Del Re A, De Palma FDE, Esposito G, Sanseverino W, Sarnelli G
International journal of molecular sciences 2021 Mar 14;22(6)
International journal of molecular sciences 2021 Mar 14;22(6)
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Zou T, Yang J, Guo X, He Q, Wang Z, You J
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
Zhang Z, Zhang Q, Li F, Xin Y, Duan Z
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
A Microfluidic Multisize Spheroid Array for Multiparametric Screening of Anticancer Drugs and Blood-Brain Barrier Transport Properties.
Eilenberger C, Rothbauer M, Selinger F, Gerhartl A, Jordan C, Harasek M, Schädl B, Grillari J, Weghuber J, Neuhaus W, Küpcü S, Ertl P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jun;8(11):e2004856
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jun;8(11):e2004856
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Shu Y, Huang J, Gao M, Gan S, Zhu S, Xu S, Yang Z, Liao Y, Lu W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
Xu D, Gao Q, Wang F, Peng Q, Wang G, Wei Q, Lei S, Zhao S, Zhang L, Guo F
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
Sun XH, Xiao HM, Zhang M, Lin ZY, Yang Y, Chen R, Liu PQ, Huang KP, Huang HQ
Biochemical pharmacology 2021 Jun;188:114562
Biochemical pharmacology 2021 Jun;188:114562
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
Zhuang M, Deng Y, Zhang W, Zhu B, Yan H, Lou J, Zhang P, Cui Q, Tang H, Sun H, Sun Y
Cell death & disease 2021 Jun 9;12(6):595
Cell death & disease 2021 Jun 9;12(6):595
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Lu L, Lu T, Shen J, Lv X, Wei W, Wang H, Xue X
Aging 2021 Jun 4;13(11):15353-15365
Aging 2021 Jun 4;13(11):15353-15365
Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut-Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation.
Yan X, Ren X, Liu X, Wang Y, Ma J, Song R, Wang X, Dong Y, Fan Q, Wei J, Yu A, She G
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7074-7083
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7074-7083
Brain endothelial LRP1 maintains blood-brain barrier integrity.
Storck SE, Kurtyka M, Pietrzik CU
Fluids and barriers of the CNS 2021 Jun 19;18(1):27
Fluids and barriers of the CNS 2021 Jun 19;18(1):27
Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNFα-promotes severe intestinal epithelial dysfunction.
Dutton JS, Hinman SS, Kim R, Attayek PJ, Maurer M, Sims CS, Allbritton NL
Integrative biology : quantitative biosciences from nano to macro 2021 Jun 15;13(6):139-152
Integrative biology : quantitative biosciences from nano to macro 2021 Jun 15;13(6):139-152
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
Chen Y, Zhang H, Chen Y, Jia P, Ji S, Zhang Y, Wang T
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Lu YZ, Liang LM, Cheng PP, Xiong L, Wang M, Song LJ, Yu F, He XL, Xiong L, Wang XR, Xin JB, Ye H, Ma WL
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Liu FY, Wen J, Hou J, Zhang SQ, Sun CB, Zhou LC, Yin W, Pang WL, Wang C, Ying Y, Han SS, Yan JY, Li CX, Yuan JL, Xing HJ, Yang ZS
International immunopharmacology 2021 Jul;96:107758
International immunopharmacology 2021 Jul;96:107758
Xiao-Xu-Ming decoction prevented hemorrhagic transformation induced by acute hyperglycemia through inhibiting AGE-RAGE-mediated neuroinflammation.
Liu N, Liu C, Yang Y, Ma G, Wei G, Liu S, Kong L, Du G
Pharmacological research 2021 Jul;169:105650
Pharmacological research 2021 Jul;169:105650
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
Wang Y, Guan X, Gao CL, Ruan W, Zhao S, Kai G, Li F, Pang T
Pharmacological research 2021 Jul;169:105640
Pharmacological research 2021 Jul;169:105640
Effects of cigarette smoke on the aggravation of ovalbumin-induced asthma and the expressions of TRPA1 and tight junctions in mice.
Sun YB, Liu M, Fan XS, Zhou LP, Li MW, Hu FY, Yue QF, Zhang YM
Molecular immunology 2021 Jul;135:62-72
Molecular immunology 2021 Jul;135:62-72
A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.
Gao C, Xu Y, Liang Z, Wang Y, Shang Q, Zhang S, Wang C, Ni M, Wu D, Huang Z, Pang T
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1867-1884
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1867-1884
Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.
Zong X, Cheng Y, Xiao X, Fu J, Wang F, Lu Z, Wang Y, Jin M
International journal of biological macromolecules 2021 Jul 31;183:861-869
International journal of biological macromolecules 2021 Jul 31;183:861-869
Effects of Coated Cysteamine on Oxidative Stress and Inflammation in Weaned Pigs.
Wang S, Bai M, Xu K, Shao Y, Yang Z, Xiong X, Huang R, Li Y, Liu H
Animals : an open access journal from MDPI 2021 Jul 27;11(8)
Animals : an open access journal from MDPI 2021 Jul 27;11(8)
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Mohammadi-Aragh MK, Stokes CE, Street JT, Linhoss JE
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Roux-en-Y gastric bypass potentially improved intestinal permeability by regulating gut innate immunity in diet-induced obese mice.
Jin Z, Chen K, Zhou Z, Peng W, Liu W
Scientific reports 2021 Jul 21;11(1):14894
Scientific reports 2021 Jul 21;11(1):14894
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
Meningitic Escherichia coli α-hemolysin aggravates blood-brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling.
Fu J, Li L, Huo D, Yang R, Yang B, Xu B, Yang X, Dai M, Tan C, Chen H, Wang X
Molecular brain 2021 Jul 19;14(1):116
Molecular brain 2021 Jul 19;14(1):116
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.
Fang M, Wan W, Li Q, Wan W, Long Y, Liu H, Yang X
Life sciences 2021 Jul 15;277:119567
Life sciences 2021 Jul 15;277:119567
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling.
Cao YY, Wang ZH, Xu QC, Chen Q, Wang Z, Lu WH
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Jul 1;25(4):375-383
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Jul 1;25(4):375-383
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Cao YY, Wang Z, Wang ZH, Jiang XG, Lu WH
International immunopharmacology 2021 Jan;90:107218
International immunopharmacology 2021 Jan;90:107218
Scratching damages tight junctions through the Akt-claudin 1 axis in atopic dermatitis.
Hu XQ, Tang Y, Ju Y, Zhang XY, Yan JJ, Wang CM, Yang Y, Zhu C, Tang ZX, Zhou Y, Yu G
Clinical and experimental dermatology 2021 Jan;46(1):74-81
Clinical and experimental dermatology 2021 Jan;46(1):74-81
CD151 Alleviates Early Blood-Brain Barrier Dysfunction After Experimental Focal Brain Ischemia in Rats.
Xu W, Gao C, Wu J
Cellular and molecular neurobiology 2021 Jan;41(1):151-162
Cellular and molecular neurobiology 2021 Jan;41(1):151-162
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Jia Z, Bao K, Wei P, Yu X, Zhang Y, Wang X, Wang X, Yao L, Li L, Wu P, Yuan W, Wang S, Zheng J, Hua Y, Hong M
Mucosal immunology 2021 Jan;14(1):125-134
Mucosal immunology 2021 Jan;14(1):125-134
Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice.
Wu H, Chen QY, Wang WZ, Chu S, Liu XX, Liu YJ, Tan C, Zhu F, Deng SJ, Dong YL, Yu T, Gao F, He HX, Leng XY, Fan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110937
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110937
A Comparison of Chitosan, Mesoporous Silica and Poly(lactic-co-glycolic) Acid Nanocarriers for Optimising Intestinal Uptake of Oral Protein Therapeutics.
Wright L, Joyce P, Barnes TJ, Lundmark R, Bergström CAS, Hubert M, Prestidge CA
Journal of pharmaceutical sciences 2021 Jan;110(1):217-227
Journal of pharmaceutical sciences 2021 Jan;110(1):217-227
Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice.
Shi Y, Zou Y, Xiong Y, Zhang S, Song M, An X, Liu C, Zhang W, Chen S
Gut microbes 2021 Jan-Dec;13(1):1946369
Gut microbes 2021 Jan-Dec;13(1):1946369
Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.
Fu J, Li L, Huo D, Zhi S, Yang R, Yang B, Xu B, Zhang T, Dai M, Tan C, Chen H, Wang X
Brain sciences 2021 Jan 8;11(1)
Brain sciences 2021 Jan 8;11(1)
Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.
Jiang K, Chen H, Fang Y, Chen L, Zhong C, Bu T, Dai S, Pan X, Fu D, Qian Y, Wei J, Ding K
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):21
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):21
Effects of Pinus massoniana pollen polysaccharides on intestinal microenvironment and colitis in mice.
Niu X, Shang H, Chen S, Chen R, Huang J, Miao Y, Cui W, Wang H, Sha Z, Peng D, Zhu R
Food & function 2021 Jan 7;12(1):252-266
Food & function 2021 Jan 7;12(1):252-266
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
Chi H, Cao W, Zhang M, Su D, Yang H, Li Z, Li C, She X, Wang K, Gao X, Ma K, Zheng P, Li X, Cui B
Journal of neuroinflammation 2021 Jan 6;18(1):9
Journal of neuroinflammation 2021 Jan 6;18(1):9
Polystyrene microplastics induced male reproductive toxicity in mice.
Jin H, Ma T, Sha X, Liu Z, Zhou Y, Meng X, Chen Y, Han X, Ding J
Journal of hazardous materials 2021 Jan 5;401:123430
Journal of hazardous materials 2021 Jan 5;401:123430
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, Huang R, Yin Y
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.
Toan NK, Tai NC, Kim SA, Ahn SG
International journal of molecular sciences 2021 Jan 2;22(1)
International journal of molecular sciences 2021 Jan 2;22(1)
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Zong X, Xiao X, Kai L, Cheng Y, Fu J, Xu W, Wang Y, Zhao K, Jin M
International journal of biological macromolecules 2021 Jan 15;167:76-84
International journal of biological macromolecules 2021 Jan 15;167:76-84
Antibiotic-induced microbiome depletion in adult mice disrupts blood-brain barrier and facilitates brain infiltration of monocytes after bone-marrow transplantation.
Sun N, Hu H, Wang F, Li L, Zhu W, Shen Y, Xiu J, Xu Q
Brain, behavior, and immunity 2021 Feb;92:102-114
Brain, behavior, and immunity 2021 Feb;92:102-114
Punicalagin Prevents Hepatic Steatosis through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western Diet-Fed Mice.
Liu H, Zhan Q, Miao X, Xia X, Yang G, Peng X, Yan C
Molecular nutrition & food research 2021 Feb;65(4):e2001031
Molecular nutrition & food research 2021 Feb;65(4):e2001031
First evidence of altered microbiota and intestinal damage and their link to absence epilepsy in a genetic animal model, the WAG/Rij rat.
Citraro R, Lembo F, De Caro C, Tallarico M, Coretti L, Iannone LF, Leo A, Palumbo D, Cuomo M, Buommino E, Nesci V, Marascio N, Iannone M, Quirino A, Russo R, Calignano A, Constanti A, Russo E, De Sarro G
Epilepsia 2021 Feb;62(2):529-541
Epilepsia 2021 Feb;62(2):529-541
Val-Val-Tyr-Pro protects against non-alcoholic steatohepatitis in mice by modulating the gut microbiota and gut-liver axis activation.
Xie X, Zhang L, Yuan S, Li H, Zheng C, Xie S, Sun Y, Zhang C, Wang R, Jin Y
Journal of cellular and molecular medicine 2021 Feb;25(3):1439-1455
Journal of cellular and molecular medicine 2021 Feb;25(3):1439-1455
Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis.
Chen J, Chen R, Huang S, Zu B, Zhang S
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Ma J, Shah AM, Wang ZS, Hu R, Zou HW, Wang XY, Zhao SN, Kong XY
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Chen KJ, Chen YL, Ueng SH, Hwang TL, Kuo LM, Hsieh PW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Induction of Epithelial-mesenchymal Transition in MDCK II Cells.
Pastuła A, Lundmark R
Bio-protocol 2021 Feb 5;11(3):e3903
Bio-protocol 2021 Feb 5;11(3):e3903
Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.
Veenstra JP, Vemu B, Tocmo R, Nauman MC, Johnson JJ
Nutrients 2021 Feb 27;13(3)
Nutrients 2021 Feb 27;13(3)
Galli gigeriae endothelium corneum: its intestinal barrier protective activity in vitro and chemical composition.
Li S, Zheng M, Zhang Z, Peng H, Dai W, Liu J
Chinese medicine 2021 Feb 16;16(1):22
Chinese medicine 2021 Feb 16;16(1):22
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Li J, Zhang L, Wu T, Li Y, Zhou X, Ruan Z
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Neutrophil extracellular traps induce a hypercoagulable state in glioma.
Zhang S, Guo M, Liu Q, Liu J, Cui Y
Immunity, inflammation and disease 2021 Dec;9(4):1383-1393
Immunity, inflammation and disease 2021 Dec;9(4):1383-1393
Salidroside protects against ventilation-induced lung injury by inhibiting the expression of matrix metalloproteinase-9.
Zhang H, Dong W, Li S, Zhang Y, Lv Z, Yang L, Jiang L, Wu T, Wang Y
Pharmaceutical biology 2021 Dec;59(1):760-768
Pharmaceutical biology 2021 Dec;59(1):760-768
Poly(ADP-ribose) polymerase inhibitor PJ34 protects against UVA-induced oxidative damage in corneal endothelium.
Wang X, Dong C, Zhou Q, Duan H, Zou D, Gong Y, Ma B, Li Z, Shi W
Apoptosis : an international journal on programmed cell death 2021 Dec;26(11-12):600-611
Apoptosis : an international journal on programmed cell death 2021 Dec;26(11-12):600-611
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Chen Y, Zhang H, Ji S, Jia P, Chen Y, Li Y, Wang T
Free radical biology & medicine 2021 Dec;177:1-14
Free radical biology & medicine 2021 Dec;177:1-14
Modified cyclodextrin-based nanoparticles mediated delivery of siRNA for huntingtin gene silencing across an in vitro BBB model.
Mendonça MCP, Cronin MF, Cryan JF, O'Driscoll CM
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2021 Dec;169:309-318
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2021 Dec;169:309-318
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Cao Q, Wei W, Wang H, Wang Z, Lv Y, Dai M, Tan C, Chen H, Wang X
Virulence 2021 Dec;12(1):2296-2313
Virulence 2021 Dec;12(1):2296-2313
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
Fan X, Xia Q, Zhang Y, Li Y, Feng Z, Zhou J, Qi J, Tang BZ, Qian J, Lin H
Advanced healthcare materials 2021 Dec;10(24):e2101043
Advanced healthcare materials 2021 Dec;10(24):e2101043
Djulis Hull Improves Insulin Resistance and Modulates the Gut Microbiota in High-Fat Diet (HFD)-Induced Hyperglycaemia.
Tung YT, Zeng JL, Ho ST, Xu JW, Lin IH, Wu JH
Antioxidants (Basel, Switzerland) 2021 Dec 26;11(1)
Antioxidants (Basel, Switzerland) 2021 Dec 26;11(1)
Dose-Dependent Relationship between Protection of Thioacetamide-Induced Acute Liver Injury and Hyperammonemia and Concentration of Lactobacillus salivarius Li01 in Mice.
Lou P, Shen Y, Zhuge A, Lv L, Zhu X, Yuan Y, Yang L, Wang K, Li B, Li L
Microbiology spectrum 2021 Dec 22;9(3):e0184721
Microbiology spectrum 2021 Dec 22;9(3):e0184721
Titanium dioxide nanoparticles perturb the blood-testis barrier via disruption of actin-based cell adhesive function.
Ni DQ, Ma DD, Hao SL, Yang WX, Kovacs T, Tan FQ
Aging 2021 Dec 14;13(23):25440-25452
Aging 2021 Dec 14;13(23):25440-25452
Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice.
Xie X, Zhou J, Hu L, Shu R, Zhang M, Xiong Z, Wu F, Fu Z
Environmental pollution (Barking, Essex : 1987) 2021 Dec 1;290:117934
Environmental pollution (Barking, Essex : 1987) 2021 Dec 1;290:117934
Intrahepatic cholestasis induced by α-naphthylisothiocyanate can cause gut-liver axis disorders.
Chen Z, Wu Y, Wang B, Fang J, Gan C, Sang C, Dun Z, Luosang T, Wang Q, Zeren D, Xiong T
Environmental toxicology and pharmacology 2021 Aug;86:103672
Environmental toxicology and pharmacology 2021 Aug;86:103672
LncRNA-MALAT1/miRNA-204-5p/Smad4 Axis Regulates Epithelial-Mesenchymal Transition, Proliferation and Migration of Lens Epithelial Cells.
Peng C, Wang Y, Ji L, Kuang L, Yu Z, Li H, Zhang J, Zhao J
Current eye research 2021 Aug;46(8):1137-1147
Current eye research 2021 Aug;46(8):1137-1147
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
Nie Y, Hui L, Guo M, Yang W, Huang R, Chen J, Wen X, Zhao M, Wu Y
Virologica Sinica 2021 Aug;36(4):692-705
Virologica Sinica 2021 Aug;36(4):692-705
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Huang L, Chen S, Fan H, Ji D, Chen C, Sheng W
Cancer gene therapy 2021 Aug;28(7-8):839-849
Cancer gene therapy 2021 Aug;28(7-8):839-849
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Bai X, Fu R, Duan Z, Wang P, Zhu C, Fan D
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Gao HN, Hu H, Wen PC, Lian S, Xie XL, Song HL, Yang ZN, Ren FZ
Journal of dairy science 2021 Aug;104(8):8411-8424
Journal of dairy science 2021 Aug;104(8):8411-8424
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Sun W, Li S, Tang G, Sun S, Luo Y, Bai R, Han L, Jiang X, Gao Y, Huang Z, Zhang J, Gong Y, Xie C
Cancer medicine 2021 Aug;10(15):5256-5269
Cancer medicine 2021 Aug;10(15):5256-5269
Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.
Liu C, Hua H, Zhu H, Cheng Y, Guo Y, Yao W, Qian H
International journal of biological macromolecules 2021 Aug 31;185:804-812
International journal of biological macromolecules 2021 Aug 31;185:804-812
Effects of Dietary Supplementation of Algae-Derived Polysaccharides on Morphology, Tight Junctions, Antioxidant Capacity and Immune Response of Duodenum in Broilers under Heat Stress.
Liu WC, Zhu YR, Zhao ZH, Jiang P, Yin FQ
Animals : an open access journal from MDPI 2021 Aug 2;11(8)
Animals : an open access journal from MDPI 2021 Aug 2;11(8)
Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets.
Gao R, Tian S, Wang J, Zhu W
Journal of animal science and biotechnology 2021 Aug 11;12(1):92
Journal of animal science and biotechnology 2021 Aug 11;12(1):92
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Jiao-Yan Y, Qing-Qing L, Xi L, Mei Z, Ting S, Na H, Wei J, Rui-Tao Z, Peng Y, Qi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Chen Y, Jiang Z, Lei Z, Ping J, Su J
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Chang Y, Deng Q, Zhang Z, Zhao H, Tang J, Chen X, Liu G, Tian G, Cai J, Jia G
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Yan M, Wang H, Gu Y, Li X, Tao L, Lu P
Experimental eye research 2021 Apr;205:108521
Experimental eye research 2021 Apr;205:108521
Multiple roles of FGF10 in the regulation of corneal endothelial wound healing.
Wang X, Zhou Q, Zhao C, Duan H, Li W, Dong C, Gong Y, Li Z, Shi W
Experimental eye research 2021 Apr;205:108517
Experimental eye research 2021 Apr;205:108517
Effects of the extract from peanut meal fermented with Bacillus natto and Monascus on lipid metabolism and intestinal barrier function of hyperlipidemic mice.
Lu Y, Ding H, Jiang X, Zhang H, Ma A, Hu Y, Li Z
Journal of the science of food and agriculture 2021 Apr;101(6):2561-2569
Journal of the science of food and agriculture 2021 Apr;101(6):2561-2569
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Bai X, Fu R, Duan Z, Liu Y, Zhu C, Fan D
Food & function 2021 Apr 7;12(7):2874-2885
Food & function 2021 Apr 7;12(7):2874-2885
Transwell Insert-Embedded Microfluidic Devices for Time-Lapse Monitoring of Alveolar Epithelium Barrier Function under Various Stimulations.
Chang SH, Ko PL, Liao WH, Peng CC, Tung YC
Micromachines 2021 Apr 6;12(4)
Micromachines 2021 Apr 6;12(4)
Impaired Colonic Contractility and Intestinal Permeability in Symptomatic Uncomplicated Diverticular Disease.
Altomare A, Gori M, Cocca S, Carotti S, Francesconi M, Ribolsi M, Emerenziani S, Perrone G, Morini S, Cicala M, Guarino MPL
Journal of neurogastroenterology and motility 2021 Apr 30;27(2):292-301
Journal of neurogastroenterology and motility 2021 Apr 30;27(2):292-301
Exosomes derived from HeLa cells break down vascular integrity by triggering endoplasmic reticulum stress in endothelial cells.
Lin Y, Zhang C, Xiang P, Shen J, Sun W, Yu H
Journal of extracellular vesicles 2020;9(1):1722385
Journal of extracellular vesicles 2020;9(1):1722385
Molecular mechanism mediating enteric bacterial translocation after severe burn: the role of cystic fibrosis transmembrane conductance regulator.
Liu X, Chen Y, You B, Peng Y, Chen Y, Yang Z, Zhang Y, Chen J
Burns & trauma 2020;9:tkaa042
Burns & trauma 2020;9:tkaa042
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Ma J, Shah AM, Wang Z, Hu R, Zou H, Wang X, Cao G, Peng Q, Xue B, Wang L, Zhao S, Kong X
PeerJ 2020;8:e9851
PeerJ 2020;8:e9851
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Yang F, Zhang Y, Zhu J, Wang J, Jiang Z, Zhao C, Yang Q, Huang Y, Yao W, Pang W, Han L, Zhou J
Frontiers in bioengineering and biotechnology 2020;8:647
Frontiers in bioengineering and biotechnology 2020;8:647
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation.
Nettleford SK, Zhao L, Qian F, Herold M, Arner B, Desai D, Amin S, Xiong N, Singh V, Carlson BA, Prabhu KS
Frontiers in nutrition 2020;7:96
Frontiers in nutrition 2020;7:96
Teasaponin Ameliorates Murine Colitis by Regulating Gut Microbiota and Suppressing the Immune System Response.
Yang H, Cai R, Kong Z, Chen Y, Cheng C, Qi S, Gu B
Frontiers in medicine 2020;7:584369
Frontiers in medicine 2020;7:584369
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Liu DY, Lou WJ, Zhang DY, Sun SY
BioMed research international 2020;2020:8819195
BioMed research international 2020;2020:8819195
Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway.
Li C, Wang X, Yan J, Cheng F, Ma X, Chen C, Wang W, Wang Q
Oxidative medicine and cellular longevity 2020;2020:1201624
Oxidative medicine and cellular longevity 2020;2020:1201624
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Wang W, Zhong M, Yu T, Chen L, Shi L, Zong J, Wang S
Nutrition & metabolism 2020;17:27
Nutrition & metabolism 2020;17:27
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Chen L, Zhang L, Wang W, Qiu W, Liu L, Ning A, Cao J, Huang M, Zhong M
PloS one 2020;15(6):e0232972
PloS one 2020;15(6):e0232972
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
Xie J, Hong E, Ding B, Jiang W, Zheng S, Xie Z, Tian D, Chen Y
Frontiers in cellular neuroscience 2020;14:578060
Frontiers in cellular neuroscience 2020;14:578060
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
Zou X, Wang Y, Wang Y, Yang J, Guo H, Cai Z
Drug design, development and therapy 2020;14:5623-5632
Drug design, development and therapy 2020;14:5623-5632
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice.
Li B, Zhou X, Yi TL, Xu ZW, Peng DW, Guo Y, Guo YM, Cao YL, Zhu L, Zhang S, Cheng SX
Frontiers in neuroscience 2020;14:403
Frontiers in neuroscience 2020;14:403
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
Zhong M, Zhu M, Liu Y, Lin Y, Wang L, Ye Y, Chen H, Yang Y, Zhuang G, Huang J
Journal of Cancer 2020;11(10):3061-3071
Journal of Cancer 2020;11(10):3061-3071
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
Hu R, He Z, Liu M, Tan J, Zhang H, Hou DX, He J, Wu S
Journal of animal science and biotechnology 2020;11:92
Journal of animal science and biotechnology 2020;11:92
H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated Nucleotide Binding Oligomerization Domain-Like Receptor Protein 3 Inflammasome Activation in Retinopathy Induced by Hyperglycemia.
Yang K, Liu J, Zhang X, Ren Z, Gao L, Wang Y, Lin W, Ma X, Hao M, Kuang H
Frontiers in pharmacology 2020;11:603689
Frontiers in pharmacology 2020;11:603689
Screening, Safety Evaluation, and Mechanism of Two Lactobacillus fermentum Strains in Reducing the Translocation of Staphylococcus aureus in the Caco-2 Monolayer Model.
Peng Z, Wei B, Huang T, Liu Z, Guan Q, Xie M, Li H, Xiong T
Frontiers in microbiology 2020;11:566473
Frontiers in microbiology 2020;11:566473
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Zhang H, Chen Y, Chen Y, Ji S, Jia P, Li Y, Wang T
Journal of animal science and biotechnology 2020;11:52
Journal of animal science and biotechnology 2020;11:52
Taurine Alleviates Intestinal Injury by Mediating Tight Junction Barriers in Diquat-Challenged Piglet Models.
Wen C, Guo Q, Wang W, Duan Y, Zhang L, Li J, He S, Chen W, Li F
Frontiers in physiology 2020;11:449
Frontiers in physiology 2020;11:449
Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells.
He S, Guo Y, Zhao J, Xu X, Wang N, Liu Q
Frontiers in pharmacology 2020;11:376
Frontiers in pharmacology 2020;11:376
1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation In Vivo and In Vitro Model.
Yi X, Xu C, Huang P, Zhang L, Qing T, Li J, Wang C, Zeng T, Lu J, Han Z
Frontiers in pharmacology 2020;11:1197
Frontiers in pharmacology 2020;11:1197
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Ding F, Wu J, Liu C, Bian Q, Qiu W, Ma Q, Li X, Long M, Zou X, Chen J
Frontiers in pharmacology 2020;11:1069
Frontiers in pharmacology 2020;11:1069
Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.
Lv W, Graves DT, He L, Shi Y, Deng X, Zhao Y, Dong X, Ren Y, Liu X, Xiao E, Zhang Y
Theranostics 2020;10(14):6500-6516
Theranostics 2020;10(14):6500-6516
Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae.
Yang T, Heydarian M, Kozjak-Pavlovic V, Urban M, Harbottle RP, Rudel T
Frontiers in cellular and infection microbiology 2020;10:422
Frontiers in cellular and infection microbiology 2020;10:422
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
Liu Y, Ma Y, Du B, Wang Y, Yang GY, Bi X
Molecular neurobiology 2020 Sep;57(9):3891-3901
Molecular neurobiology 2020 Sep;57(9):3891-3901
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Shi L, Liu BY, Wang X, Zhu MJ, Chen L, Zhou MY, Gu YJ, Cheng L, Wang Y
Cell stress & chaperones 2020 Sep;25(5):793-802
Cell stress & chaperones 2020 Sep;25(5):793-802
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Li Y, Ye H, Wang T, Wang P, Liu R, Li Y, Tian Y, Zhang J
Marine drugs 2020 Sep 29;18(10)
Marine drugs 2020 Sep 29;18(10)
Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids.
Yoshimoto S, Yoshizumi J, Anzai H, Morishita K, Okamura K, Hiraki A, Hashimoto S
Disease models & mechanisms 2020 Sep 28;13(9)
Disease models & mechanisms 2020 Sep 28;13(9)
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Furutama D, Matsuda S, Yamawaki Y, Hatano S, Okanobu A, Memida T, Oue H, Fujita T, Ouhara K, Kajiya M, Mizuno N, Kanematsu T, Tsuga K, Kurihara H
Brain sciences 2020 Sep 27;10(10)
Brain sciences 2020 Sep 27;10(10)
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Yang Q, Luo L, Sun T, Yang L, Cheng LF, Wang Y, Liu QQ, Liu A, Liu HY, Zhao MG, Wu SX, Feng B
Psychopharmacology 2020 Oct;237(10):3201-3213
Psychopharmacology 2020 Oct;237(10):3201-3213
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening.
Sondorp LHJ, Ogundipe VML, Groen AH, Kelder W, Kemper A, Links TP, Coppes RP, Kruijff S
Cancers 2020 Oct 31;12(11)
Cancers 2020 Oct 31;12(11)
Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice.
Li L, Li R, Zhu R, Chen B, Tian Y, Zhang H, Xia B, Jia Q, Wang L, Zhao D, Mo F, Li Y, Zhang S, Gao S, Zhang D, Guo S
Food & function 2020 Oct 21;11(10):8743-8756
Food & function 2020 Oct 21;11(10):8743-8756
Bioinformatics analysis of LINC01554 and its co‑expressed genes in hepatocellular carcinoma.
Li L, Huang K, Lu Z, Zhao H, Li H, Ye Q, Peng G
Oncology reports 2020 Nov;44(5):2185-2197
Oncology reports 2020 Nov;44(5):2185-2197
Protective effect of Lactobacillus salivarius Li01 on thioacetamide-induced acute liver injury and hyperammonaemia.
Yang L, Bian X, Wu W, Lv L, Li Y, Ye J, Jiang X, Wang Q, Shi D, Fang D, Wu J, Wang K, Wang Q, Xia J, Xie J, Lu Y, Li L
Microbial biotechnology 2020 Nov;13(6):1860-1876
Microbial biotechnology 2020 Nov;13(6):1860-1876
Anthocyanins decrease the internalization of TiO(2) nanoparticles into 3D Caco-2 spheroids.
Wang J, Zhang J, Li S, Huang C, Xie Y, Cao Y
Food chemistry 2020 Nov 30;331:127360
Food chemistry 2020 Nov 30;331:127360
Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.
Jiang Z, Mu W, Yang Y, Sun M, Liu Y, Gao Z, Li J, Gu P, Wang H, Lu Y, Ba Q, Wang H
The Science of the total environment 2020 Nov 20;744:140844
The Science of the total environment 2020 Nov 20;744:140844
Novel Pentapeptide Derived from Chicken by-Product Ameliorates DSS-Induced Colitis by Enhancing Intestinal Barrier Function via AhR-Induced Src Inactivation.
Li S, Ma B, Wang J, Peng H, Zheng M, Dai W, Liu J
Journal of agricultural and food chemistry 2020 Nov 19;
Journal of agricultural and food chemistry 2020 Nov 19;
Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress.
Xiao Q, Shu R, Wu C, Tong Y, Xiong Z, Zhou J, Yu C, Xie X, Fu Z
Journal of affective disorders 2020 Nov 1;276:476-486
Journal of affective disorders 2020 Nov 1;276:476-486
Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway.
Jia Y, Cui R, Wang C, Feng Y, Li Z, Tong Y, Qu K, Liu C, Zhang J
Redox biology 2020 May;32:101534
Redox biology 2020 May;32:101534
Effect of MicroRNA-126a-3p on Bone Marrow Mesenchymal Stem Cells Repairing Blood-brain Barrier and Nerve Injury after Intracerebral Hemorrhage.
Wang C, Cao J, Duan S, Xu R, Yu H, Huo X, Qian Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 May;29(5):104748
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 May;29(5):104748
Small airway remodeling in diabetic and smoking chronic obstructive pulmonary disease patients.
Wu N, Wu Z, Sun J, Yan M, Wang B, Du X, Liu Y
Aging 2020 May 5;12(9):7927-7944
Aging 2020 May 5;12(9):7927-7944
Exposure to nonylphenol in early life increases pro-inflammatory cytokines in the prefrontal cortex: Involvement of gut-brain communication.
Che X, Fang Y, You M, Xu Y, Wang Y
Chemico-biological interactions 2020 May 25;323:109076
Chemico-biological interactions 2020 May 25;323:109076
Palmitic Acid Affects Intestinal Epithelial Barrier Integrity and Permeability In Vitro.
Gori M, Altomare A, Cocca S, Solida E, Ribolsi M, Carotti S, Rainer A, Francesconi M, Morini S, Cicala M, Guarino MPL
Antioxidants (Basel, Switzerland) 2020 May 13;9(5)
Antioxidants (Basel, Switzerland) 2020 May 13;9(5)
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Wu DM, Deng SH, Zhou J, Han R, Liu T, Zhang T, Li J, Chen JP, Xu Y
International journal of cancer 2020 May 1;146(9):2563-2575
International journal of cancer 2020 May 1;146(9):2563-2575
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Wang X, Liu M, Zhu MJ, Shi L, Liu L, Zhao YL, Cheng L, Gu YJ, Zhou MY, Chen L, Kumar A, Wang Y
Cell proliferation 2020 Mar;53(3):e12773
Cell proliferation 2020 Mar;53(3):e12773
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Huang M, Wang Q, Long F, Di Y, Wang J, Zhun Zhu Y, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions.
Li H, Fan C, Lu H, Feng C, He P, Yang X, Xiang C, Zuo J, Tang W
Acta pharmaceutica Sinica. B 2020 Mar;10(3):447-461
Acta pharmaceutica Sinica. B 2020 Mar;10(3):447-461
Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia.
Liu S, Dai Y, Zhou C, Zhu T
Journal of toxicology and environmental health. Part A 2020 Mar 3;83(5):203-214
Journal of toxicology and environmental health. Part A 2020 Mar 3;83(5):203-214
A PTAL-miR-101-FN1 Axis Promotes EMT and Invasion-Metastasis in Serous Ovarian Cancer.
Liang H, Yu M, Yang R, Zhang L, Zhang L, Zhu D, Luo H, Hong Y, Yu T, Sun J, Shan H, Gu Y
Molecular therapy oncolytics 2020 Mar 27;16:53-62
Molecular therapy oncolytics 2020 Mar 27;16:53-62
Jiao-tai-wan inhibits inflammation of the gut-brain-axis and attenuates cognitive impairment in insomnic rats.
Su H, Zhang C, Zou X, Lu F, Zeng Y, Guan H, Ren Y, Yuan F, Xu L, Zhang M, Dong H
Journal of ethnopharmacology 2020 Mar 25;250:112478
Journal of ethnopharmacology 2020 Mar 25;250:112478
Methamphetamine-induced alterations in intestinal mucosal barrier function occur via the microRNA-181c/ TNF-α/tight junction axis.
Shen S, Zhao J, Dai Y, Chen F, Zhang Z, Yu J, Wang K
Toxicology letters 2020 Mar 15;321:73-82
Toxicology letters 2020 Mar 15;321:73-82
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Yin J, Zhou C, Yang K, Ren Y, Qiu Y, Xu P, Xiao W, Yang H
Cell biology international 2020 Jun;44(6):1405-1414
Cell biology international 2020 Jun;44(6):1405-1414
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way.
Wu Y, Wu B, Zhang Z, Lu H, Fan C, Qi Q, Gao Y, Li H, Feng C, Zuo J, Tang W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8028-8043
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8028-8043
CD147 Promoted Epithelial Mesenchymal Transition in Airway Epithelial Cells Induced by Cigarette Smoke via Oxidative Stress Signaling Pathway.
Zhou H, Liu Y, Wang Z, Yang Y, Li M, Yuan D, Zhang X, Li Y
COPD 2020 Jun;17(3):269-279
COPD 2020 Jun;17(3):269-279
microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.
Wu J, He J, Tian X, Luo Y, Zhong J, Zhang H, Li H, Cen B, Jiang T, Sun X
Journal of neurochemistry 2020 Jun;153(6):710-726
Journal of neurochemistry 2020 Jun;153(6):710-726
ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch.
Shimizu A, Goh WH, Itai S, Hashimoto M, Miura S, Onoe H
Lab on a chip 2020 Jun 2;20(11):1917-1927
Lab on a chip 2020 Jun 2;20(11):1917-1927
Ursodeoxycholic Acid Halts Pathological Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy.
Thounaojam MC, Jadeja RN, Rajpurohit S, Gutsaeva DR, Stansfield BK, Martin PM, Bartoli M
Journal of clinical medicine 2020 Jun 19;9(6)
Journal of clinical medicine 2020 Jun 19;9(6)
Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease.
Uemasu K, Tanabe N, Tanimura K, Hasegawa K, Mizutani T, Hamakawa Y, Sato S, Ogawa E, Thomas MJ, Ikegami M, Muro S, Hirai T, Sato A
American journal of respiratory cell and molecular biology 2020 Jul;63(1):67-78
American journal of respiratory cell and molecular biology 2020 Jul;63(1):67-78
TBC1D20 Is Essential for Mouse Blood-Testis Barrier Integrity Through Maintaining the Epithelial Phenotype and Modulating the Maturation of Sertoli Cells.
Cui L, Gu Y, Liu S, Li M, Ye J, Zhang F, Luo X, Chang WL, Gui Y
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jul;27(7):1443-1454
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jul;27(7):1443-1454
Platelet regulates neuroinflammation and restores blood-brain barrier integrity in a mouse model of traumatic brain injury.
Gao C, Wang H, Wang T, Luo C, Wang Z, Zhang M, Chen X, Tao L
Journal of neurochemistry 2020 Jul;154(2):190-204
Journal of neurochemistry 2020 Jul;154(2):190-204
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.
Sun X, Huang K, Haiming X, Lin Z, Yang Y, Zhang M, Liu P, Huang H
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1573-1592
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1573-1592
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Bai R, Sun D, Chen M, Shi X, Luo L, Yao Z, Liu Y, Ge X, Gao X, Hu GF, Zhou W, Sheng J, Xu Z
The EMBO journal 2020 Jul 1;39(13):e103325
The EMBO journal 2020 Jul 1;39(13):e103325
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Zhu C, Zhao L, Zhao J, Zhang S
International journal of molecular medicine 2020 Jan;45(1):53-60
International journal of molecular medicine 2020 Jan;45(1):53-60
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
Guo F, Xu D, Lin Y, Wang G, Wang F, Gao Q, Wei Q, Lei S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, Wen S, Zhao D, Wu H, Chen J, Sun Y, Duan Z
Archives of microbiology 2020 Jan;202(1):161-169
Archives of microbiology 2020 Jan;202(1):161-169
Identification of differentially expressed genes and signaling pathways involved in endometriosis by integrated bioinformatics analysis.
Dai FF, Bao AY, Luo B, Zeng ZH, Pu XL, Wang YQ, Zhang L, Xian S, Yuan MQ, Yang DY, Liu SY, Cheng YX
Experimental and therapeutic medicine 2020 Jan;19(1):264-272
Experimental and therapeutic medicine 2020 Jan;19(1):264-272
Protective Effect of Naringin on In Vitro Gut-Vascular Barrier Disruption of Intestinal Microvascular Endothelial Cells Induced by TNF-α.
Liu P, Bian Y, Fan Y, Zhong J, Liu Z
Journal of agricultural and food chemistry 2020 Jan 8;68(1):168-175
Journal of agricultural and food chemistry 2020 Jan 8;68(1):168-175
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Jiang YP, Ye RJ, Yang JM, Liu N, Zhang WJ, Ma L, Sun T, Niu JG, Zheng P, Yu JQ
Chemico-biological interactions 2020 Jan 5;315:108869
Chemico-biological interactions 2020 Jan 5;315:108869
Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion.
Lu Z, Zhang D, Cui K, Fu X, Man J, Lu H, Yu L, Gao Y, Liu X, Liao L, Li X, Liu C, Zhang Y, Zhang Z, Wang J
Neuroscience 2020 Jan 21;428:228-241
Neuroscience 2020 Jan 21;428:228-241
Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling.
Sheng W, Shi X, Lin Y, Tang J, Jia C, Cao R, Sun J, Wang G, Zhou L, Dong M
Journal of experimental & clinical cancer research : CR 2020 Jan 17;39(1):16
Journal of experimental & clinical cancer research : CR 2020 Jan 17;39(1):16
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Melatonin protects the mouse testis against heat-induced damage.
Zhang P, Zheng Y, Lv Y, Li F, Su L, Qin Y, Zeng W
Molecular human reproduction 2020 Feb 29;26(2):65-79
Molecular human reproduction 2020 Feb 29;26(2):65-79
Peripheral inflammation promotes brain tau transmission via disrupting blood-brain barrier.
Liu Y, Zhang S, Li X, Liu E, Wang X, Zhou Q, Ye J, Wang JZ
Bioscience reports 2020 Feb 28;40(2)
Bioscience reports 2020 Feb 28;40(2)
Environmental lead exposure aggravates the progression of Alzheimer's disease in mice by targeting on blood brain barrier.
Wu S, Liu H, Zhao H, Wang X, Chen J, Xia D, Xiao C, Cheng J, Zhao Z, He Y
Toxicology letters 2020 Feb 1;319:138-147
Toxicology letters 2020 Feb 1;319:138-147
Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice.
Wang S, Chen Q, Zhang Y, Zheng F, Xue T, Ge X, Ma R, Li X, Wu R, Liang K, Qian Z, Ge Y, Ma J, Yao B
Reproductive toxicology (Elmsford, N.Y.) 2020 Dec;98:233-241
Reproductive toxicology (Elmsford, N.Y.) 2020 Dec;98:233-241
Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats.
Khazoom F, L'Écuyer S, Gilbert K, Gagné MA, Bouchard C, Rose CF, Rousseau G, Charbonney E
The journal of trauma and acute care surgery 2020 Dec;89(6):1076-1084
The journal of trauma and acute care surgery 2020 Dec;89(6):1076-1084
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Hu Q, Lan J, Liang W, Chen Y, Chen B, Liu Z, Xiong Y, Zhong Z, Wang Y, Ye Q
Journal of molecular histology 2020 Dec;51(6):685-700
Journal of molecular histology 2020 Dec;51(6):685-700
Icariside II attenuates cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction in rats via regulating the balance of MMP9/TIMP1.
Liu MB, Wang W, Gao JM, Li F, Shi JS, Gong QH
Acta pharmacologica Sinica 2020 Dec;41(12):1547-1556
Acta pharmacologica Sinica 2020 Dec;41(12):1547-1556
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Zhu H, Xiao X, Shi Y, Wu Y, Huang Y, Li D, Xiong F, He G, Chai Y, Tang H
Experimental and therapeutic medicine 2020 Dec;20(6):155
Experimental and therapeutic medicine 2020 Dec;20(6):155
Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice.
Chen Q, Wang Y, Jiao F, Shi C, Pei M, Wang L, Gong Z
Scientific reports 2020 Dec 14;10(1):21850
Scientific reports 2020 Dec 14;10(1):21850
Polysaccharide from the seeds of Plantago asiatica L. alleviates nonylphenol induced intestinal barrier injury by regulating tight junctions in human Caco-2 cell line.
Li F, Du P, Yang W, Huang D, Nie S, Xie M
International journal of biological macromolecules 2020 Dec 1;164:2134-2140
International journal of biological macromolecules 2020 Dec 1;164:2134-2140
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Tian M, Ma P, Zhang Y, Mi Y, Fan D
International immunopharmacology 2020 Aug;85:106645
International immunopharmacology 2020 Aug;85:106645
Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain.
Zhou YQ, Liu DQ, Chen SP, Chen N, Sun J, Wang XM, Cao F, Tian YK, Ye DW
Acta pharmacologica Sinica 2020 Aug;41(8):1041-1048
Acta pharmacologica Sinica 2020 Aug;41(8):1041-1048
Salvianolic acid B protects against myocardial ischaemia-reperfusion injury in rats via inhibiting high mobility group box 1 protein expression through the PI3K/Akt signalling pathway.
Liu H, Liu W, Qiu H, Zou D, Cai H, Chen Q, Zheng C, Xu D
Naunyn-Schmiedeberg's archives of pharmacology 2020 Aug;393(8):1527-1539
Naunyn-Schmiedeberg's archives of pharmacology 2020 Aug;393(8):1527-1539
A self-driven bioinspired nanovehicle by leukocyte membrane-hitchhiking for early detection and treatment of atherosclerosis.
Wu G, Wei W, Zhang J, Nie W, Yuan L, Huang Y, Zuo L, Huang L, Xi X, Xie HY
Biomaterials 2020 Aug;250:119963
Biomaterials 2020 Aug;250:119963
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Cong LH, Li T, Wang H, Wu YN, Wang SP, Zhao YY, Zhang GQ, Duan J
Journal of cellular and molecular medicine 2020 Aug;24(15):8532-8544
Journal of cellular and molecular medicine 2020 Aug;24(15):8532-8544
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Wu J, He J, Tian X, Zhong J, Li H, Sun X
Translational stroke research 2020 Aug;11(4):720-733
Translational stroke research 2020 Aug;11(4):720-733
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Morgan SE, Schroten H, Ishikawa H, Zhao N
Brain sciences 2020 Aug 8;10(8)
Brain sciences 2020 Aug 8;10(8)
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Tan J, Liu H, Huang M, Li N, Tang S, Meng J, Tang S, Zhou H, Kijlstra A, Yang P, Hou S
Cell death & disease 2020 Aug 22;11(8):697
Cell death & disease 2020 Aug 22;11(8):697
Metformin therapy confers cardioprotection against the remodeling of gap junction in tachycardia-induced atrial fibrillation dog model.
Li J, Li B, Bai F, Ma Y, Liu N, Liu Y, Wang Y, Liu Q
Life sciences 2020 Aug 1;254:117759
Life sciences 2020 Aug 1;254:117759
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Guo H, He J, Yang X, Zheng W, Yao W
Journal of thermal biology 2020 Apr;89:102539
Journal of thermal biology 2020 Apr;89:102539
Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice.
Li P, Wu M, Xiong W, Li J, An Y, Ren J, Xie Y, Xue H, Yan D, Li M, Zhong G
International immunopharmacology 2020 Apr;81:106288
International immunopharmacology 2020 Apr;81:106288
Protective effect of Dioscorea zingiberensis ethanol extract on the disruption of blood-testes barrier in high-fat diet/streptozotocin-induced diabetic mice by upregulating ZO-1 and Nrf2.
Zhou J, Xi Y, Zhang J, Tang J, Zhou X, Chen J, Nie C, Zhu Z, Ma B
Andrologia 2020 Apr;52(3):e13508
Andrologia 2020 Apr;52(3):e13508
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
Bai L, Liang J, Li L, Li E
Oncology reports 2020 Apr;43(4):1208-1220
Oncology reports 2020 Apr;43(4):1208-1220
Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage.
Li X, Yao Z, Yang D, Jiang X, Sun J, Tian L, Hu J, Wu B, Bai W
Journal of hazardous materials 2020 Apr 5;387:121706
Journal of hazardous materials 2020 Apr 5;387:121706
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
He J, Jiang YL, Wang Y, Tian XJ, Sun SR
Chinese medical journal 2020 Apr 5;133(7):800-807
Chinese medical journal 2020 Apr 5;133(7):800-807
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis.
Li H, Feng C, Fan C, Yang Y, Yang X, Lu H, Lu Q, Zhu F, Xiang C, Zhang Z, He P, Zuo J, Tang W
Cell death & disease 2020 Apr 24;11(4):271
Cell death & disease 2020 Apr 24;11(4):271
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage.
Li M, Liu G, Wang K, Wang L, Fu X, Lim LY, Chen W, Mo J
Journal of nanobiotechnology 2020 Apr 19;18(1):61
Journal of nanobiotechnology 2020 Apr 19;18(1):61
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
Cheng Y, Wu T, Tang S, Liang F, Fang Y, Cao W, Pan S, Xu X
Food & function 2020 Apr 1;11(4):3167-3179
Food & function 2020 Apr 1;11(4):3167-3179
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L
Theranostics 2019;9(17):5065-5084
Theranostics 2019;9(17):5065-5084
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291
Frontiers in oncology 2019;9:291
Building a Thick Mucus Hydrogel Layer to Improve the Physiological Relevance of In Vitro Primary Colonic Epithelial Models.
Wang Y, Kim R, Sims CE, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2019;8(4):653-655.e5
Cellular and molecular gastroenterology and hepatology 2019;8(4):653-655.e5
Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds.
Li D, Yuan D, Shen H, Mao X, Yuan S, Liu Q
Molecular vision 2019;25:625-635
Molecular vision 2019;25:625-635
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Guo Y, Huang C, Liu L, Fu X, Lu Y, Zheng J, Mei Q, Huang Z, Fan J, Lu L, Zeng Y
Mediators of inflammation 2019;2019:8474523
Mediators of inflammation 2019;2019:8474523
Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Zhuang Y, Wu H, Wang X, He J, He S, Yin Y
Oxidative medicine and cellular longevity 2019;2019:7591840
Oxidative medicine and cellular longevity 2019;2019:7591840
Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis.
Yan Z, Yang F, Hong Z, Wang S, Jinjuan Z, Han B, Xie R, Leng F, Yang Q
Canadian journal of gastroenterology & hepatology 2019;2019:5236149
Canadian journal of gastroenterology & hepatology 2019;2019:5236149
High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis.
Su YR, Hong YP, Mei FC, Wang CY, Li M, Zhou Y, Zhao KL, Yu J, Wang WX
Mediators of inflammation 2019;2019:2512687
Mediators of inflammation 2019;2019:2512687
Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking.
Speer JE, Gunasekara DB, Wang Y, Fallon JK, Attayek PJ, Smith PC, Sims CE, Allbritton NL
Journal of biological engineering 2019;13:36
Journal of biological engineering 2019;13:36
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Tang G, Zeng Z, Sun W, Li S, You C, Tang F, Peng S, Ma S, Luo Y, Xu J, Tian X, Zhang N, Gong Y, Xie C
Journal of Cancer 2019;10(10):2261-2275
Journal of Cancer 2019;10(10):2261-2275
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
Hu L, Wu C, Zhang Z, Liu M, Maruthi Prasad E, Chen Y, Wang K
Frontiers in physiology 2019;10:908
Frontiers in physiology 2019;10:908
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, Gong Z, Zeng Q, Wei Y, Yang W, Zeng Z, He X, Huang SH, Cao H
Frontiers in microbiology 2019;10:477
Frontiers in microbiology 2019;10:477
Licochalcone A Protects the Blood-Milk Barrier Integrity and Relieves the Inflammatory Response in LPS-Induced Mastitis.
Guo W, Liu B, Yin Y, Kan X, Gong Q, Li Y, Cao Y, Wang J, Xu D, Ma H, Fu S, Liu J
Frontiers in immunology 2019;10:287
Frontiers in immunology 2019;10:287
Administration of Akkermansia muciniphila Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Bian X, Wu W, Yang L, Lv L, Wang Q, Li Y, Ye J, Fang D, Wu J, Jiang X, Shi D, Li L
Frontiers in microbiology 2019;10:2259
Frontiers in microbiology 2019;10:2259
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
Heydarian M, Yang T, Schweinlin M, Steinke M, Walles H, Rudel T, Kozjak-Pavlovic V
Frontiers in microbiology 2019;10:1740
Frontiers in microbiology 2019;10:1740
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Bao K, Yuan W, Zhou Y, Chen Y, Yu X, Wang X, Jia Z, Yu X, Wang X, Yao L, Wang S, Xu Y, Zhang Y, Zheng J, Hong M
Frontiers in pharmacology 2019;10:1698
Frontiers in pharmacology 2019;10:1698
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
Zong X, Cao X, Wang H, Xiao X, Wang Y, Lu Z
Frontiers in immunology 2019;10:1674
Frontiers in immunology 2019;10:1674
The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1.
Ott T, Kaufmann L, Granzow M, Hinderhofer K, Bartram CR, Theiß S, Seitz A, Paramasivam N, Schulz A, Moog U, Blum M, Evers CM
Frontiers in physiology 2019;10:134
Frontiers in physiology 2019;10:134
Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection.
Martins Gomes SF, Westermann AJ, Sauerwein T, Hertlein T, Förstner KU, Ohlsen K, Metzger M, Shusta EV, Kim BJ, Appelt-Menzel A, Schubert-Unkmeir A
Frontiers in microbiology 2019;10:1181
Frontiers in microbiology 2019;10:1181
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Nan D, Jin H, Deng J, Yu W, Liu R, Sun W, Huang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Luo L, Liu Y, Cai X, Wang Y, Xue J, Zhang J, Yang F
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Yang JM, Sun Y, Wang M, Zhang XL, Zhang SJ, Gao YS, Chen L, Wu MY, Zhou L, Zhou YM, Wang Y, Zheng FJ, Li YH
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Li X, Mao M, Zhang Y, Yu K, Zhu W
Biomolecules 2019 Sep 13;9(9)
Biomolecules 2019 Sep 13;9(9)
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Chen Y, Chen JQ, Ge MM, Zhang Q, Wang XQ, Zhu JY, Xie CF, Li XT, Zhong CY, Han HY
The Journal of nutritional biochemistry 2019 Oct;72:108219
The Journal of nutritional biochemistry 2019 Oct;72:108219
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Lan XB, Wang Q, Yang JM, Ma L, Zhang WJ, Zheng P, Sun T, Niu JG, Liu N, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Zhang J, Yao D, Song Y, Pan Y, Zhu L, Bai Y, Xu Y, Zhang J, Shao C
Scientific reports 2019 Oct 23;9(1):15221
Scientific reports 2019 Oct 23;9(1):15221
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Wang X, Adegoke EO, Ma M, Huang F, Zhang H, Adeniran SO, Zheng P, Zhang G
Theriogenology 2019 Oct 15;138:84-93
Theriogenology 2019 Oct 15;138:84-93
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
Ren MT, Gu ML, Zhou XX, Yu MS, Pan HH, Ji F, Ding CY
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z
Toxicology letters 2019 Nov;316:109-118
Toxicology letters 2019 Nov;316:109-118
Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro.
Li CX, Wang XQ, Cheng FF, Yan X, Luo J, Wang QG
Neural regeneration research 2019 Nov;14(11):1941-1949
Neural regeneration research 2019 Nov;14(11):1941-1949
The effects of c-Src kinase on EMT signaling pathway in human lens epithelial cells associated with lens diseases.
Li X, Wang F, Ren M, Du M, Zhou J
BMC ophthalmology 2019 Nov 8;19(1):219
BMC ophthalmology 2019 Nov 8;19(1):219
An in vitro intestinal platform with a self-sustaining oxygen gradient to study the human gut/microbiome interface.
Kim R, Attayek PJ, Wang Y, Furtado KL, Tamayo R, Sims CE, Allbritton NL
Biofabrication 2019 Nov 6;12(1):015006
Biofabrication 2019 Nov 6;12(1):015006
The protective effect of selenium from heat stress-induced porcine small intestinal epithelial cell line (IPEC-J2) injury is associated with regulation expression of selenoproteins.
Tang J, Cao L, Jia G, Liu G, Chen X, Tian G, Cai J, Shang H, Zhao H
The British journal of nutrition 2019 Nov 28;122(10):1081-1090
The British journal of nutrition 2019 Nov 28;122(10):1081-1090
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Wang J, Zhang C, Guo C, Li X
International journal of molecular sciences 2019 Nov 15;20(22)
International journal of molecular sciences 2019 Nov 15;20(22)
Chitosan coating of zein-carboxymethylated short-chain amylose nanocomposites improves oral bioavailability of insulin in vitro and in vivo.
Ji N, Hong Y, Gu Z, Cheng L, Li Z, Li C
Journal of controlled release : official journal of the Controlled Release Society 2019 Nov 10;313:1-13
Journal of controlled release : official journal of the Controlled Release Society 2019 Nov 10;313:1-13
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Xia Y, Chen S, Zhao Y, Chen S, Huang R, Zhu G, Yin Y, Ren W, Deng J
Food & function 2019 Nov 1;10(11):7509-7522
Food & function 2019 Nov 1;10(11):7509-7522
TIMM50 promotes tumor progression via ERK signaling and predicts poor prognosis of non-small cell lung cancer patients.
Zhang X, Han S, Zhou H, Cai L, Li J, Liu N, Liu Y, Wang L, Fan C, Li A, Miao Y
Molecular carcinogenesis 2019 May;58(5):767-776
Molecular carcinogenesis 2019 May;58(5):767-776
Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway.
Yin M, Shen Z, Yang L, Zheng W, Song H
International journal of molecular medicine 2019 May;43(5):2086-2102
International journal of molecular medicine 2019 May;43(5):2086-2102
Activation of SIRT1 ameliorates LPS-induced lung injury in mice via decreasing endothelial tight junction permeability.
Fu C, Hao S, Xu X, Zhou J, Liu Z, Lu H, Wang L, Jin W, Li S
Acta pharmacologica Sinica 2019 May;40(5):630-641
Acta pharmacologica Sinica 2019 May;40(5):630-641
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Propofol Protects Lung Endothelial Barrier Function by Suppression of High-Mobility Group Box 1 (HMGB1) Release and Mitochondrial Oxidative Damage Catalyzed by HMGB1.
Feng Z, Wang JW, Wang Y, Dong WW, Xu ZF
Medical science monitor : international medical journal of experimental and clinical research 2019 May 1;25:3199-3211
Medical science monitor : international medical journal of experimental and clinical research 2019 May 1;25:3199-3211
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Zhou F, Jiang Z, Yang B, Hu Z
Brain, behavior, and immunity 2019 Mar;77:161-167
Brain, behavior, and immunity 2019 Mar;77:161-167
Epidermal growth factor treatment has protective effects on the integrity of the blood-brain barrier against cerebral ischemia injury in bEnd3 cells.
Yang S, Jin H, Zhao ZG
Experimental and therapeutic medicine 2019 Mar;17(3):2397-2402
Experimental and therapeutic medicine 2019 Mar;17(3):2397-2402
Cold-inducible RNA-binding protein as a novel target to alleviate blood-brain barrier damage induced by cardiopulmonary bypass.
Liu M, Li Y, Liu Y, Yan S, Liu G, Zhang Q, Ji B
The Journal of thoracic and cardiovascular surgery 2019 Mar;157(3):986-996.e5
The Journal of thoracic and cardiovascular surgery 2019 Mar;157(3):986-996.e5
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Liu X, Dong H, Huang B, Miao H, Xu Z, Yuan Y, Qiu F, Chen J, Zhang H, Liu Z, Quan X, Zhu L, Zhang Z
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Ethyl pyruvate protects against Salmonella intestinal infection in mice through down-regulation of pro-inflammatory factors and inhibition of TLR4/MAPK pathway.
Dong N, Xu X, Xue C, Wang C, Li X, Shan A, Xu L, Li D
International immunopharmacology 2019 Jun;71:155-163
International immunopharmacology 2019 Jun;71:155-163
Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells.
Adegoke EO, Adeniran SO, Zeng Y, Wang X, Wang H, Wang C, Zhang H, Zheng P, Zhang G
Journal of applied toxicology : JAT 2019 Jun;39(6):832-843
Journal of applied toxicology : JAT 2019 Jun;39(6):832-843
ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling.
Zhu D, Zhou J, Zhao J, Jiang G, Zhang X, Zhang Y, Dong M
Journal of cellular physiology 2019 Jun;234(6):8899-8907
Journal of cellular physiology 2019 Jun;234(6):8899-8907
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Scheiber IF, Wu Y, Morgan SE, Zhao N
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Wang XM, Li QY, Ren LL, Liu YM, Wang TS, Mu TC, Fu S, Liu C, Xiao JY
Cellular signalling 2019 Jul;59:171-181
Cellular signalling 2019 Jul;59:171-181
Connexin43 dephosphorylation at serine 282 is associated with connexin43-mediated cardiomyocyte apoptosis.
Yang Y, Yan X, Xue J, Zheng Y, Chen M, Sun Z, Liu T, Wang C, You H, Luo D
Cell death and differentiation 2019 Jul;26(7):1332-1345
Cell death and differentiation 2019 Jul;26(7):1332-1345
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.
Li H, Fan C, Feng C, Wu Y, Lu H, He P, Yang X, Zhu F, Qi Q, Gao Y, Zuo J, Tang W
British journal of pharmacology 2019 Jul;176(13):2209-2226
British journal of pharmacology 2019 Jul;176(13):2209-2226
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
Sun S, Cai B, Li Y, Su W, Zhao X, Gong B, Li Z, Zhang X, Wu Y, Chen C, Tsang SH, Yang J, Li X
Aging 2019 Jul 7;11(13):4323-4337
Aging 2019 Jul 7;11(13):4323-4337
Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system.
Li C, Wang X, Cheng F, Du X, Yan J, Zhai C, Mu J, Wang Q
European journal of pharmacology 2019 Jul 5;854:224-231
European journal of pharmacology 2019 Jul 5;854:224-231
The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice.
Zhang M, Zhao J, Deng J, Duan Z, Zhu C, Fan D
Food & function 2019 Jul 17;10(7):4124-4133
Food & function 2019 Jul 17;10(7):4124-4133
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
Yuan W, Ji J, Shu Y, Chen J, Liu S, Wu L, Zhou Z, Liu Z, Tang Q, Zhang X, Shu X
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, Jin L, Li S
Cellular signalling 2019 Jan;53:151-161
Cellular signalling 2019 Jan;53:151-161
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Liu Z, Chen J, Yuan W, Ruan H, Shu Y, Ji J, Wu L, Tang Q, Zhou Z, Zhang X, Cheng Y, He S, Shu X
Cancer science 2019 Jan;110(1):86-98
Cancer science 2019 Jan;110(1):86-98
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, Zhong C, Li X
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Cao W, Wang C, Chin Y, Chen X, Gao Y, Yuan S, Xue C, Wang Y, Tang Q
Food & function 2019 Jan 22;10(1):277-288
Food & function 2019 Jan 22;10(1):277-288
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Wang J, Tian S, Yu H, Wang J, Zhu W
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension.
Wang J, Yu M, Xu J, Cheng Y, Li X, Wei G, Wang H, Kong H, Xie W
Journal of biomedical science 2019 Jan 12;26(1):6
Journal of biomedical science 2019 Jan 12;26(1):6
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
Zhai J, Geng X, Ding T, Li J, Tang J, Chen D, Cui L, Wang Q
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
LncRNA CRNDE promotes the epithelial-mesenchymal transition of hepatocellular carcinoma cells via enhancing the Wnt/β-catenin signaling pathway.
Zhu L, Yang N, Du G, Li C, Liu G, Liu S, Xu Y, Di Y, Pan W, Li X
Journal of cellular biochemistry 2019 Feb;120(2):1156-1164
Journal of cellular biochemistry 2019 Feb;120(2):1156-1164
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Li J, Hao Y, Mao W, Xue X, Xu P, Liu L, Yuan J, Zhang D, Li N, Chen H, Zhao L, Sun Z, Luo J, Chen R, Zhao RC
Journal of hematology & oncology 2019 Feb 22;12(1):19
Journal of hematology & oncology 2019 Feb 22;12(1):19
Vanillin protects the blood-milk barrier and inhibits the inflammatory response in LPS-induced mastitis in mice.
Guo W, Liu B, Hu G, Kan X, Li Y, Gong Q, Xu D, Ma H, Cao Y, Huang B, Fu S, Liu J
Toxicology and applied pharmacology 2019 Feb 15;365:9-18
Toxicology and applied pharmacology 2019 Feb 15;365:9-18
Ezrin, a Membrane Cytoskeleton Cross-Linker Protein, as a Marker of Epithelial Damage in Asthma.
Jia M, Yan X, Jiang X, Wu Y, Xu J, Meng Y, Yang Y, Shan X, Zhang X, Mao S, Gu W, Pavlidis S, Barnes PJ, Adcock IM, Huang M, Yao X
American journal of respiratory and critical care medicine 2019 Feb 15;199(4):496-507
American journal of respiratory and critical care medicine 2019 Feb 15;199(4):496-507
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
Chai S, Liu K, Feng W, Liu T, Wang Q, Zhou R, Chen S, Wang L, Chen G, Ming T, Zhao J, Liu C, Xue B
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.
Wang X, Zou Y, Li Y, Chen Z, Yin C, Wang Y, Zhang L, Wu J, Yang C, Zhang G, Zou Y, Gong H
Genes to cells : devoted to molecular & cellular mechanisms 2019 Dec;24(12):789-800
Genes to cells : devoted to molecular & cellular mechanisms 2019 Dec;24(12):789-800
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Fan X, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota.
Wu M, Li P, An Y, Ren J, Yan D, Cui J, Li D, Li M, Wang M, Zhong G
Pharmacological research 2019 Dec;150:104489
Pharmacological research 2019 Dec;150:104489
Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats.
Li XX, Ling SK, Hu MY, Ma Y, Li Y, Huang PL
Free radical biology & medicine 2019 Dec;145:175-186
Free radical biology & medicine 2019 Dec;145:175-186
The role of sphingosine 1-phosphate receptors on retinal pigment epithelial cells barrier function and angiogenic effects.
Terao R, Honjo M, Totsuka K, Miwa Y, Kurihara T, Aihara M
Prostaglandins & other lipid mediators 2019 Dec;145:106365
Prostaglandins & other lipid mediators 2019 Dec;145:106365
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Jiang YP, Yang JM, Ye RJ, Liu N, Zhang WJ, Ma L, Zheng P, Niu JG, Liu P, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, Wang Q, Ni Z, Mou S, Dai H, Pang H, Gu L
Cell death & disease 2019 Dec 4;10(12):915
Cell death & disease 2019 Dec 4;10(12):915
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
You M, Miao Z, Pan Y, Hu F
European journal of pharmacology 2019 Dec 15;865:172736
European journal of pharmacology 2019 Dec 15;865:172736
Oral delivery of a Lactococcus lactis strain secreting bovine lactoferricin-lactoferrampin alleviates the development of acute colitis in mice.
Song L, Xie W, Liu Z, Guo D, Zhao D, Qiao X, Wang L, Zhou H, Cui W, Jiang Y, Li Y, Xu Y, Tang L
Applied microbiology and biotechnology 2019 Aug;103(15):6169-6186
Applied microbiology and biotechnology 2019 Aug;103(15):6169-6186
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Sun L, Zhang W, Li Z, Li M, Guo J, Wang H, Wang X
Scientific reports 2019 Aug 8;9(1):11510
Scientific reports 2019 Aug 8;9(1):11510
Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice.
Zhu X, Ye Y, Xu C, Gao C, Zhang Y, Zhou J, Lin W, Mao J
Cell communication and signaling : CCS 2019 Aug 6;17(1):91
Cell communication and signaling : CCS 2019 Aug 6;17(1):91
Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells.
Kim BJ, McDonagh MA, Deng L, Gastfriend BD, Schubert-Unkmeir A, Doran KS, Shusta EV
Fluids and barriers of the CNS 2019 Aug 22;16(1):26
Fluids and barriers of the CNS 2019 Aug 22;16(1):26
Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy.
Song P, Li Y, Dong Y, Liang Y, Qu H, Qi D, Lu Y, Jin X, Guo Y, Jia Y, Wang X, Xu W, Quan C
Journal of experimental & clinical cancer research : CR 2019 Aug 14;38(1):354
Journal of experimental & clinical cancer research : CR 2019 Aug 14;38(1):354
Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices.
Frost TS, Jiang L, Lynch RM, Zohar Y
Micromachines 2019 Aug 13;10(8)
Micromachines 2019 Aug 13;10(8)
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
Xu J, Wei G, Wang J, Zhu J, Yu M, Zeng X, Wang H, Xie W, Kong H
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
Tan B, Luo W, Shen Z, Xiao M, Wu S, Meng X, Wu X, Yang Z, Tian L, Wang X
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Li X, Dong M, Zhou J, Zhu D, Zhao J, Sheng W
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Butyrate Protects Mice Against Methionine-Choline-Deficient Diet-Induced Non-alcoholic Steatohepatitis by Improving Gut Barrier Function, Attenuating Inflammation and Reducing Endotoxin Levels.
Ye J, Lv L, Wu W, Li Y, Shi D, Fang D, Guo F, Jiang H, Yan R, Ye W, Li L
Frontiers in microbiology 2018;9:1967
Frontiers in microbiology 2018;9:1967
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Huang Y, He J, Liang H, Hu K, Jiang S, Yang L, Mei S, Zhu X, Yu J, Kijlstra A, Yang P, Hou S
Frontiers in immunology 2018;9:1713
Frontiers in immunology 2018;9:1713
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Wang Y, Kim R, Gunasekara DB, Reed MI, DiSalvo M, Nguyen DL, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Effects of Dietary Serine Supplementation on Intestinal Integrity, Inflammation and Oxidative Status in Early-Weaned Piglets.
Zhou X, Zhang Y, Wu X, Wan D, Yin Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):993-1002
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):993-1002
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
Xiao Z, Liu L, Tao W, Pei X, Wang G, Wang M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway.
Wang Y, Chen H, Chen Q, Jiao FZ, Zhang WB, Gong ZJ
Mediators of inflammation 2018;2018:7859601
Mediators of inflammation 2018;2018:7859601
Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases.
Chen X, Liu R, Liu X, Xu C, Wang X
BioMed research international 2018;2018:7207268
BioMed research international 2018;2018:7207268
Volatile Oil of Amomum villosum Inhibits Nonalcoholic Fatty Liver Disease via the Gut-Liver Axis.
Lu S, Zhang T, Gu W, Yang X, Lu J, Zhao R, Yu J
BioMed research international 2018;2018:3589874
BioMed research international 2018;2018:3589874
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
Yu M, Wang Q, Ma Y, Li L, Yu K, Zhang Z, Chen G, Li X, Xiao W, Xu P, Yang H
International journal of biological sciences 2018;14(1):69-77
International journal of biological sciences 2018;14(1):69-77
A novel SWIM domain protein ZSWIM5 inhibits the malignant progression of non-small-cell lung cancer.
Xu K, Liu B, Ma Y, Xu B, Xing X
Cancer management and research 2018;10:3245-3254
Cancer management and research 2018;10:3245-3254
ZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling.
Liu B, Xing X, Li X, Guo Q, Xu T, Xu K
Cancer management and research 2018;10:3159-3168
Cancer management and research 2018;10:3159-3168
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Ma J, Yin G, Lu Z, Xie P, Zhou H, Liu J, Yu L
Phytotherapy research : PTR 2018 Sep;32(9):1770-1783
Phytotherapy research : PTR 2018 Sep;32(9):1770-1783
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Jia Z, Wang X, Wang X, Wei P, Li L, Wu P, Hong M
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
Luo L, Zhou Z, Xue J, Wang Y, Zhang J, Cai X, Liu Y, Yang F
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Li M, Wen Y, Zhang R, Xie F, Zhang G, Qin X
Brain research bulletin 2018 Sep;142:54-62
Brain research bulletin 2018 Sep;142:54-62
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Adegoke EO, Wang C, Machebe NS, Wang X, Wang H, Adeniran SO, Zhang H, Zheng P, Zhang G
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Adegoke EO, Wang X, Wang H, Wang C, Zhang H, Zhang G
Biological trace element research 2018 Oct;185(2):332-343
Biological trace element research 2018 Oct;185(2):332-343
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.
Wang W, Hu Y, Yang C, Zhu S, Wang X, Zhang Z, Deng H
Molecular & cellular proteomics : MCP 2018 Oct;17(10):2005-2017
Molecular & cellular proteomics : MCP 2018 Oct;17(10):2005-2017
Fluoride altered rat's blood testis barrier by affecting the F-actin via IL-1α.
He X, Sun Z, Manthari RK, Wu P, Wang J
Chemosphere 2018 Nov;211:826-833
Chemosphere 2018 Nov;211:826-833
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Wu YY, Li TM, Zang LQ, Liu B, Wang GX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Yan M, Yang X, Shen R, Wu C, Wang H, Ye Q, Yang P, Zhang L, Chen M, Wan B, Zhang Q, Xia S, Lu X, Shao G, Zhou X, Yu J, Shao Q
Cell death & disease 2018 Nov 8;9(11):1123
Cell death & disease 2018 Nov 8;9(11):1123
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
Yang Y, Dong B, Lu J, Wang G, Yu Y
Brain research 2018 Nov 15;1699:177-185
Brain research 2018 Nov 15;1699:177-185
Autocrine transforming growth factor-β/activin A-Smad signaling induces hepatic progenitor cells undergoing partial epithelial-mesenchymal transition states.
Wu Y, Ding ZY, Jin GN, Xiong YX, Yu B, Sun YM, Wang W, Liang HF, Zhang B, Chen XP
Biochimie 2018 May;148:87-98
Biochimie 2018 May;148:87-98
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
Wang X, Zhang X, Hu L, Li H
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD.
Yu M, Chen Y, Li X, Yang R, Zhang L, Huangfu L, Zheng N, Zhao X, Lv L, Hong Y, Liang H, Shan H
Cell death & disease 2018 May 1;9(5):464
Cell death & disease 2018 May 1;9(5):464
Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood-Brain Barrier Permeability During Early Reperfusion in Stroke.
Zhang S, An Q, Wang T, Gao S, Zhou G
Neuroscience 2018 May 1;377:126-137
Neuroscience 2018 May 1;377:126-137
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Liu Z, Li L, Chen W, Wang Q, Xiao W, Ma Y, Sheng B, Li X, Sun L, Yu M, Yang H
International journal of molecular medicine 2018 Mar;41(3):1560-1572
International journal of molecular medicine 2018 Mar;41(3):1560-1572
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
Zhang X, Jiang G, Wu J, Zhou H, Zhang Y, Miao Y, Feng Y, Yu J
Oncology letters 2018 Mar;15(3):3806-3813
Oncology letters 2018 Mar;15(3):3806-3813
ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD(+)-Mediated Epithelial-Mesenchymal Transition.
Wang W, Hu Y, Wang X, Wang Q, Deng H
Cell chemical biology 2018 Mar 15;25(3):255-261.e4
Cell chemical biology 2018 Mar 15;25(3):255-261.e4
miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1.
Liu L, Yao J, Li Z, Zu G, Feng D, Li Y, Qasim W, Zhang S, Li T, Zeng H, Tian X
Cell death & disease 2018 Mar 14;9(3):411
Cell death & disease 2018 Mar 14;9(3):411
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
NIK‑ and IKKβ‑binding protein contributes to gastric cancer chemoresistance by promoting epithelial‑mesenchymal transition through the NF‑κB signaling pathway.
Fu ZH, Liu SQ, Qin MB, Huang JA, Xu CY, Wu WH, Zhu LY, Qin N, Lai MY
Oncology reports 2018 Jun;39(6):2721-2730
Oncology reports 2018 Jun;39(6):2721-2730
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Zhang Z, Zhang L, Chen J, Cao Y, Qu M, Lin X, Han Z, Ji X
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Effects of chronic noise exposure on the microbiome-gut-brain axis in senescence-accelerated prone mice: implications for Alzheimer's disease.
Cui B, Su D, Li W, She X, Zhang M, Wang R, Zhai Q
Journal of neuroinflammation 2018 Jun 22;15(1):190
Journal of neuroinflammation 2018 Jun 22;15(1):190
Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis.
Ye JZ, Li YT, Wu WR, Shi D, Fang DQ, Yang LY, Bian XY, Wu JJ, Wang Q, Jiang XW, Peng CG, Ye WC, Xia PC, Li LJ
World journal of gastroenterology 2018 Jun 21;24(23):2468-2481
World journal of gastroenterology 2018 Jun 21;24(23):2468-2481
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Chen X, Hong M, Yang Q, Wang J
Journal of neuroinflammation 2018 Jun 21;15(1):188
Journal of neuroinflammation 2018 Jun 21;15(1):188
Tail Vein Infusion of Adipose-Derived Mesenchymal Stem Cell Alleviated Inflammatory Response and Improved Blood Brain Barrier Condition by Suppressing Endoplasmic Reticulum Stress in a Middle Cerebral Artery Occlusion Rat Model.
Chi L, Huang Y, Mao Y, Wu K, Zhang L, Nan G
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 11;24:3946-3957
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 11;24:3946-3957
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Crotty Alexander LE, Drummond CA, Hepokoski M, Mathew D, Moshensky A, Willeford A, Das S, Singh P, Yong Z, Lee JH, Vega K, Du A, Shin J, Javier C, Tian J, Brown JH, Breen EC
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
Lipopolysaccharide Induces Subacute Cerebral Microhemorrhages with Involvement of Nitric Oxide Synthase in Rats.
Zeng J, Zhào H, Liu Z, Zhang W, Huang Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jul;27(7):1905-1913
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jul;27(7):1905-1913
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)
Nutrients 2018 Jul 31;10(8)
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Liu M, Yang J, Zhang Y, Zhou Z, Cui X, Zhang L, Fung KM, Zheng W, Allard FD, Yee EU, Ding K, Wu H, Liang Z, Zheng L, Fernandez-Zapico ME, Li YP, Bronze MS, Morris KT, Postier RG, Houchen CW, Yang J, Li M
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Zou Y, Ma L, Zhao Y, Zhang S, Zhou C, Cai Y
International journal of molecular medicine 2018 Jan;41(1):430-438
International journal of molecular medicine 2018 Jan;41(1):430-438
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Zhang DD, Jin C, Zhang YT, Gan XD, Zou MJ, Wang YY, Fu WL, Xu T, Xing WW, Xia WR, Xu DG
Journal of neuroinflammation 2018 Jan 15;15(1):16
Journal of neuroinflammation 2018 Jan 15;15(1):16
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
Yang S, Jin H, Zhao Z
Neurological research 2018 Feb;40(2):117-121
Neurological research 2018 Feb;40(2):117-121
A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells.
Tian H, Xu JY, Tian Y, Cao Y, Lian C, Ou Q, Wu B, Jin C, Gao F, Wang J, Zhang J, Zhang J, Li W, Lu L, Xu GT
Experimental eye research 2018 Dec;177:160-172
Experimental eye research 2018 Dec;177:160-172
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Wang S, Xie T, Sun S, Wang K, Liu B, Wu X, Ding W
Scientific reports 2018 Dec 12;8(1):17788
Scientific reports 2018 Dec 12;8(1):17788
Paracellular tightness and the functional expression of efflux transporters P-gp and BCRP in bEnd3 cells.
Yang S, Jin H, Zhao Z
Neurological research 2018 Aug;40(8):644-649
Neurological research 2018 Aug;40(8):644-649
Metformin Protects against LPS-Induced Intestinal Barrier Dysfunction by Activating AMPK Pathway.
Wu W, Wang S, Liu Q, Shan T, Wang Y
Molecular pharmaceutics 2018 Aug 6;15(8):3272-3284
Molecular pharmaceutics 2018 Aug 6;15(8):3272-3284
Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury.
Main BS, Villapol S, Sloley SS, Barton DJ, Parsadanian M, Agbaegbu C, Stefos K, McCann MS, Washington PM, Rodriguez OC, Burns MP
Molecular neurodegeneration 2018 Apr 4;13(1):17
Molecular neurodegeneration 2018 Apr 4;13(1):17
Potential Orphan Drug Therapy of Intravesical Liposomal Onabotulinumtoxin-A for Ketamine-Induced Cystitis by Mucosal Protection and Anti-inflammation in a Rat Model.
Lee WC, Su CH, Tain YL, Tsai CN, Yu CC, Chuang YC
Scientific reports 2018 Apr 11;8(1):5795
Scientific reports 2018 Apr 11;8(1):5795
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Zhang T, Lu SH, Bi Q, Liang L, Wang YF, Yang XX, Gu W, Yu J
Frontiers in pharmacology 2017;8:786
Frontiers in pharmacology 2017;8:786
Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense.
Zeng Q, He X, Puthiyakunnon S, Xiao H, Gong Z, Boddu S, Chen L, Tian H, Huang SH, Cao H
Frontiers in microbiology 2017;8:1798
Frontiers in microbiology 2017;8:1798
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Li L, Wang N, Jin Q, Wu Q, Liu Y, Wang Y
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Calycosin Suppresses Epithelial Derived Initiative Key Factors and Maintains Epithelial Barrier in Allergic Inflammation via TLR4 Mediated NF-κB Pathway.
Tao Y, Wang Y, Wang X, Wang C, Bao K, Ji L, Jiang G, Hong M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(3):1106-1119
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(3):1106-1119
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Yang S, Mei S, Jin H, Zhu B, Tian Y, Huo J, Cui X, Guo A, Zhao Z
PloS one 2017;12(10):e0187017
PloS one 2017;12(10):e0187017
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Li W, Li X, Liu S, Yang W, Pan F, Yang XY, Du B, Qin L, Pan Y
International journal of nanomedicine 2017;12:3509-3520
International journal of nanomedicine 2017;12:3509-3520
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Zhang X, Zhou H, Cai L, Fan C, Liu Y, Wang L, Li Q, Miao Y
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
Zhang X, Liu Y, Fan C, Wang L, Li A, Zhou H, Cai L, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Sep 26;8(43):75102-75113
Oncotarget 2017 Sep 26;8(43):75102-75113
TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
Zhang X, Zhang Y, Miao Y, Zhou H, Jiang G, Wang E
Oncotarget 2017 Sep 19;8(41):70685-70694
Oncotarget 2017 Sep 19;8(41):70685-70694
Role of macrophage migration inhibitory factor (MIF) in the effects of oxidative stress on human retinal pigment epithelial cells.
Ko JA, Sotani Y, Ibrahim DG, Kiuchi Y
Cell biochemistry and function 2017 Oct;35(7):426-432
Cell biochemistry and function 2017 Oct;35(7):426-432
The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-κB Inhibition.
Zhang L, Zhang Z, Liu B, Jin Y, Tian Y, Xin Y, Duan Z
Molecular medicine (Cambridge, Mass.) 2017 Oct;23:215-224
Molecular medicine (Cambridge, Mass.) 2017 Oct;23:215-224
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Sheng W, Chen C, Dong M, Wang G, Zhou J, Song H, Li Y, Zhang J, Ding S
Cell death & disease 2017 Oct 26;8(10):e3147
Cell death & disease 2017 Oct 26;8(10):e3147
Administration of alpha-ketoglutarate improves epithelial restitution under stress injury in early-weaning piglets.
He L, Zhou X, Huang N, Li H, Cui Z, Tian J, Jiang Q, Liu S, Wu J, Li T, Yao K, Yin Y
Oncotarget 2017 Nov 3;8(54):91965-91978
Oncotarget 2017 Nov 3;8(54):91965-91978
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
Han J, Li JH, Bai G, Shen GS, Chen J, Liu JN, Wang S, Liu XJ
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Zhang X, Zhou H, Zhang Y, Cai L, Jiang G, Li A, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Jun 13;8(24):38863-38875
Oncotarget 2017 Jun 13;8(24):38863-38875
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Wang Y, DiSalvo M, Gunasekara DB, Dutton J, Proctor A, Lebhar MS, Williamson IA, Speer J, Howard RL, Smiddy NM, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Du J, Zhang X, Zhou H, Miao Y, Han Y, Han Q, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Small Interfering RNA Targeting Dickkopf-1 Contributes to Neuroprotection After Intracerebral Hemorrhage in Rats.
Li Z, Chen X, Zhang X, Ren X, Chen X, Cao J, Zang W, Liu X, Guo F
Journal of molecular neuroscience : MN 2017 Feb;61(2):279-288
Journal of molecular neuroscience : MN 2017 Feb;61(2):279-288
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Zhang X, Jiang G, Sun M, Zhou H, Miao Y, Liang M, Wang E, Zhang Y
Oncotarget 2017 Feb 21;8(8):13357-13366
Oncotarget 2017 Feb 21;8(8):13357-13366
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
Zhang X, Cai L, Zhou H, Liu Y, Fan C, Wang L, Li A, Miao Y, Li Q, Qiu X, Wang E
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
Targeted deletion of Aqp4 promotes the formation of astrocytic gap junctions.
Katoozi S, Skauli N, Rahmani S, Camassa LMA, Boldt HB, Ottersen OP, Amiry-Moghaddam M
Brain structure & function 2017 Dec;222(9):3959-3972
Brain structure & function 2017 Dec;222(9):3959-3972
Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.
Appelt-Menzel A, Cubukova A, Günther K, Edenhofer F, Piontek J, Krause G, Stüber T, Walles H, Neuhaus W, Metzger M
Stem cell reports 2017 Apr 11;8(4):894-906
Stem cell reports 2017 Apr 11;8(4):894-906
CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation.
Ramena G, Yin Y, Yu Y, Walia V, Elble RC
PloS one 2016;11(3):e0147489
PloS one 2016;11(3):e0147489
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Yang R, Liu W, Miao L, Yang X, Fu J, Dou B, Cai A, Zong X, Tan C, Chen H, Wang X
Oncotarget 2016 Sep 27;7(39):63839-63855
Oncotarget 2016 Sep 27;7(39):63839-63855
Phenotype transformation of immortalized NCM460 colon epithelial cell line by TGF-β1 is associated with chromosome instability.
Huang C, Wen B
Molecular biology reports 2016 Oct;43(10):1069-78
Molecular biology reports 2016 Oct;43(10):1069-78
A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells.
Kong J, Luo Y, Jin D, An F, Zhang W, Liu L, Li J, Fang S, Li X, Yang X, Lin B, Liu T
Oncotarget 2016 Nov 29;7(48):78421-78432
Oncotarget 2016 Nov 29;7(48):78421-78432
SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.
Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W
JCI insight 2016 Nov 17;1(19):e86934
JCI insight 2016 Nov 17;1(19):e86934
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Suzuki R, Nakamura Y, Chiba S, Mizuno T, Abe K, Horii Y, Nagashima H, Tanita T, Yamauchi K
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Knockout of BRD7 results in impaired spermatogenesis and male infertility.
Wang H, Zhao R, Guo C, Jiang S, Yang J, Xu Y, Liu Y, Fan L, Xiong W, Ma J, Peng S, Zeng Z, Zhou Y, Li X, Li Z, Li X, Schmitt DC, Tan M, Li G, Zhou M
Scientific reports 2016 Feb 16;6:21776
Scientific reports 2016 Feb 16;6:21776
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Wang ZG, Cheng Y, Yu XC, Ye LB, Xia QH, Johnson NR, Wei X, Chen DQ, Cao G, Fu XB, Li XK, Zhang HY, Xiao J
Molecular neurobiology 2016 Dec;53(10):7298-7311
Molecular neurobiology 2016 Dec;53(10):7298-7311
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Han J, Liu L, Yu N, Chen J, Liu B, Yang D, Shen G
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
Sun L, Xu C, Chen G, Yu M, Yang S, Qiu Y, Peng K, Wang W, Xiao W, Yang H
International journal of biological sciences 2015;11(6):664-71
International journal of biological sciences 2015;11(6):664-71
Naturally Occurring Stilbenoid TSG Reverses Non-Alcoholic Fatty Liver Diseases via Gut-Liver Axis.
Lin P, Lu J, Wang Y, Gu W, Yu J, Zhao R
PloS one 2015;10(10):e0140346
PloS one 2015;10(10):e0140346
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Yu X, Zhang X, Zhang Y, Jiang G, Mao X, Jin F
Oncotarget 2015 Sep 22;6(28):25034-45
Oncotarget 2015 Sep 22;6(28):25034-45
Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism.
Dong WW, Liu YJ, Lv Z, Mao YF, Wang YW, Zhu XY, Jiang L
Free radical biology & medicine 2015 Nov;88(Pt B):404-416
Free radical biology & medicine 2015 Nov;88(Pt B):404-416
Par-3 modulates intestinal epithelial barrier function through regulating intracellular trafficking of occludin and myosin light chain phosphorylation.
Yu M, Yang S, Qiu Y, Chen G, Wang W, Xu C, Cai W, Sun L, Xiao W, Yang H
Journal of gastroenterology 2015 Nov;50(11):1103-13
Journal of gastroenterology 2015 Nov;50(11):1103-13
The multi-targeted tyrosine kinase inhibitor vandetanib plays a bifunctional role in non-small cell lung cancer cells.
Zhou Y, Zhang Y, Zou H, Cai N, Chen X, Xu L, Kong X, Liu P
Scientific reports 2015 Feb 27;5:8629
Scientific reports 2015 Feb 27;5:8629
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
Zhang X, Miao Y, Yu X, Zhang Y, Jiang G, Liu Y, Yu J, Han Q, Zhao H, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
Miao L, Xiong X, Lin Y, Cheng Y, Lu J, Zhang J, Cheng N
Oncology letters 2014 Mar;7(3):658-662
Oncology letters 2014 Mar;7(3):658-662
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
Yang F, Wang Z, Wei X, Han H, Meng X, Zhang Y, Shi W, Li F, Xin T, Pang Q, Yi F
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Ning Q, Liu C, Hou L, Meng M, Zhang X, Luo M, Shao S, Zuo X, Zhao X
PloS one 2013;8(6):e65217
PloS one 2013;8(6):e65217
Keratinocyte growth factor pretreatment prevents radiation-induced intestinal damage in a mouse model.
Cai Y, Wang W, Liang H, Sun L, Teitelbaum DH, Yang H
Scandinavian journal of gastroenterology 2013 Apr;48(4):419-26
Scandinavian journal of gastroenterology 2013 Apr;48(4):419-26
Increased epithelial permeability is the primary cause for bicarbonate loss in inflamed murine colon.
Juric M, Xiao F, Amasheh S, May O, Wahl K, Bantel H, Manns MP, Seidler U, Bachmann O
Inflammatory bowel diseases 2013 Apr;19(5):904-11
Inflammatory bowel diseases 2013 Apr;19(5):904-11
Keratinocyte growth factor improves epithelial structure and function in a mouse model of intestinal ischemia/reperfusion.
Cai Y, Wang W, Liang H, Sun L, Teitelbaum DH, Yang H
PloS one 2012;7(9):e44772
PloS one 2012;7(9):e44772
Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier.
Eilert-Olsen M, Haj-Yasein NN, Vindedal GF, Enger R, Gundersen GA, Hoddevik EH, Petersen PH, Haug FM, Skare Ø, Adams ME, Froehner SC, Burkhardt JM, Thoren AE, Nagelhus EA
Glia 2012 Mar;60(3):432-40
Glia 2012 Mar;60(3):432-40
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 21773-1-AP(ZO1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21773-1-AP(ZO1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21773-1-AP(ZO1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ZO-1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ZO-1. This antibody recognizes human antigen. The ZO-1 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
