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- Antibody Data
- Antigen structure
- References [1115]
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- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 21773-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21773-1-AP, RRID:AB_10733242
- Product name
- ZO-1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ZO-1 antibody (Cat. #21773-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, Canine, mouse, rat, hamster and has been validated for the following applications: FC, IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Canine, Hamster
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Therapeutic Effects of Lifei Decoction in a Murine Model of COPD Induced by LPS and Cigarette Smoke.
Trimethylamine N-oxide aggravates vascular permeability and endothelial cell dysfunction under diabetic condition: in vitro and in vivo study.
The Predictive Value of Serum DAO, HDC, and MMP8 for the Gastrointestinal Injury in the Early Stage of Acute Pancreatitis in an Animal Model and a Clinical Study.
TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway.
Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation.
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.
Interaction of Neisseria meningitidis carrier and disease isolates of MenB cc32 and MenW cc22 with epithelial cells of the nasopharyngeal barrier.
Nocardia rubra cell-wall skeleton mitigates whole abdominal irradiation-induced intestinal injury via regulating macrophage function.
In vitro co-culture of Clostridium scindens with primary human colonic epithelium protects the epithelium against Staphylococcus aureus.
MMP-2-mediated Scube2 degradation promotes blood-brain barrier disruption by blocking the interaction between astrocytes and endothelial cells via inhibiting Sonic hedgehog pathway during early cerebral ischemia.
Cinnamaldehyde alleviates aspirin-induced gastric mucosal injury by regulating pi3k/akt pathway-mediated apoptosis, autophagy and ferroptosis.
Intestinal NSD2 Aggravates Nonalcoholic Steatohepatitis Through Histone Modifications.
Gut microbiota dysbiosis contributes to α-synuclein-related pathology associated with C/EBPβ/AEP signaling activation in a mouse model of Parkinson's disease.
Streptococcus salivarius ameliorates the destructive effect on the epithelial barrier by inhibiting the growth of Prevotella melaninogenica via metabolic acid production.
Linagliptin's impact on lymphatic barrier and lymphangiogenesis in oral cancer with high glucose.
Epigallocatechin gallate alleviated the in vivo toxicity of ZnO nanoparticles to mouse intestine.
Tongfu Lifei Decoction Attenuated Sepsis-Related Intestinal Mucosal Injury Through Regulating Th17/Treg Balance and Modulating Gut Microbiota.
Carnosol alleviates sepsis-induced pulmonary endothelial barrier dysfunction by targeting nuclear factor erythroid2-related factor 2/sirtuin-3 signaling pathway to attenuate oxidative damage.
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Prevotella melaninogenica disrupted oral epithelial barrier function via myosin light chain kinase.
Anchang Yuyang Decoction inhibits experimental colitis-related carcinogenesis by regulating PPAR signaling pathway and affecting metabolic homeostasis of host and microbiota.
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
FGF17 protects cerebral ischemia reperfusion-induced blood-brain barrier disruption via FGF receptor 3-mediated PI3K/AKT signaling pathway.
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
Metformin attenuates lung ischemia-reperfusion injury and necroptosis through AMPK pathway in type 2 diabetic recipient rats.
An investigation into the HIF-dependent intestinal barrier protective mechanism of Qingchang Wenzhong decoction in ulcerative colitis management.
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3.
Minimally invasive vagus nerve stimulation modulates mast cell degranulation via the microbiota-gut-brain axis to ameliorate blood-brain barrier and intestinal barrier damage following ischemic stroke.
Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice.
Ginsenoside CK Alleviates DSS-Induced IBD in Mice by Regulating Tryptophan Metabolism and Activating Aryl Hydrocarbon Receptor via Gut Microbiota Modulation.
Cuproptosis mediates copper-induced testicular spermatogenic cell death.
Narirutin Attenuates Cerebral Ischemia-Reperfusion Injury by Suppressing the TXNIP/NLRP3 Pathway.
Inhibition of EphA4 reduces vasogenic edema after experimental stroke in mice by protecting the blood-brain barrier integrity.
Age-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.
Cornuside protects against ischemic stroke in rats by suppressing the IL-17F/TRAF6/NF-κB pathway via the brain-gut axis.
Engineered mesenchymal stem cell-derived small extracellular vesicles for diabetic retinopathy therapy through HIF-1α/EZH2/PGC-1α pathway.
Selective HDAC6 inhibition protects against blood-brain barrier dysfunction after intracerebral hemorrhage.
Ageratina adenophora causes intestinal integrity damage in goats via the activation of the MLCK/ROCK signaling pathway.
Golden bifid treatment regulates gut microbiota and serum metabolites to improve myocardial dysfunction in cecal ligation and puncture-induced sepsis mice.
Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora.
Zinc lactate alleviates oxidative stress by modulating crosstalk between constitutive androstane receptor signaling pathway and gut microbiota profile in weaned piglets.
AhR Activation Ameliorates Intestinal Barrier Damage in Immunostressed Piglets by Regulating Intestinal Flora and Its Metabolism.
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Environmentally realistic dose of tire-derived metabolite 6PPD-Q exposure causes intestinal jejunum and ileum damage in mice via cannabinoid receptor-activated inflammation.
RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells.
Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model.
Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline-Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora.
Selenomethionine Alleviates Deoxynivalenol-Induced Oxidative Injury in Porcine Intestinal Epithelial Cells Independent of MAPK Pathway Regulation.
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
Trifluoperazine regulates blood-brain barrier permeability via the MLCK/p-MLC pathway to promote ischemic stroke recovery.
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice.
Achyranthes bidentata polysaccharide ameliorates type 2 diabetes mellitus by gut microbiota-derived short-chain fatty acids-induced activation of the GLP-1/GLP-1R/cAMP/PKA/CREB/INS pathway.
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner.
Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 pathway.
Rosa laevigata Polysaccharides Ameliorate Dextran Sulfate Sodium-Induced Ulcerative Colitis of Beagles through Regulating Gut Microbiota.
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Effect and mechanism of Prunella vulgaris L. extract on alleviating lipopolysaccharide-induced acute mastitis in protecting the blood-milk barrier and reducing inflammation.
MyD88 Inhibition Attenuates Cerebral Ischemia-reperfusion Injury by Regulating the Inflammatory Response and Reducing Blood-brain Barrier Damage.
Astrocytes-Secreted WNT5B Disrupts the Blood-Brain Barrier Via ROR1/JNK/c-JUN Cascade During Meningitic Escherichia Coli Infection.
Elucidating the modulatory role of dietary hydroxyproline on the integrity and functional performance of the intestinal barrier in early-weaned piglets: A comprehensive analysis of its interplay with the gut microbiota and metabolites.
Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier.
Development of an Inflamed High Throughput Stem-cell-based Gut Epithelium Model to Assess the Impact of Annexin A1.
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Dietary emulsifier polysorbate 80 exposure accelerates age-related cognitive decline.
Narirutin mitigates dextrose sodium sulfate-induced colitis in mice by modulating intestinal flora.
High correlated color temperature artificial lighting impairs retinal pigment epithelium integrity and chloride ion transport: A potential mechanism for choroidal thinning.
Neuroprotection of macamide in a mouse model of Alzheimer's disease involves Nrf2 signaling pathway and gut microbiota.
pH Sensitive Quercetin Nanoparticles Ameliorate DSS-Induced Colitis in Mice by Colon-Specific Delivery.
Addition of α-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems.
Quercetin ameliorates ulcerative colitis by activating aryl hydrocarbon receptor to improve intestinal barrier integrity.
Simultaneous ischemic regions targeting and BBB crossing strategy to harness extracellular vesicles for therapeutic delivery in ischemic stroke.
Angiotensin-converting enzyme inhibitory peptide IVGFPAYGH protects against liver injury in mice fed a high‑sodium diet by inhibiting the RAS and remodeling gut microbial communities.
Chitosan-coated artesunate protects against ulcerative colitis via STAT6-mediated macrophage M2 polarization and intestinal barrier protection.
PSD-95 inhibitor Tat-NR2B9c (NA-1) protects the integrity of the blood-brain barrier after transient middle artery occlusion in rats by downregulating matrix metalloprotease-9 and upregulating endothelial nitric oxide synthase.
An Erythrocyte Membrane-Derived Nanosystem for Efficient Reversal of Endothelial Injury in Sepsis.
The protective effects of icariin against testicular dysfunction in type 1 diabetic mice Via AMPK-mediated Nrf2 activation and NF-κB p65 inhibition.
Cantharidin-induced toxic injury, oxidative stress, and autophagy attenuated by Astragalus polysaccharides in mouse testis.
Probiotic Clostridium butyricum ameliorates cognitive impairment in obesity via the microbiota-gut-brain axis.
Prevotella copri promotes vascular calcification via lipopolysaccharide through activation of NF-κB signaling pathway.
Meta-analysis identifying gut microbial biomarkers of Qinghai-Tibet Plateau populations and the functionality of microbiota-derived butyrate in high-altitude adaptation.
Renal macrophages monitor and remove particles from urine to prevent tubule obstruction.
Study on the Anti-Ulcerative Colitis Effect of Pseudo-Ginsenoside RT4 Based on Gut Microbiota, Pharmacokinetics, and Tissue Distribution.
Macrophage-derived MMP12 promotes fibrosis through sustained damage to endothelial cells.
Inhibition of circulating exosomes release with GW4869 mitigates severe acute pancreatitis-stimulated intestinal barrier damage through suppressing NLRP3 inflammasome-mediated pyroptosis.
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
FTO-mediated m6A modification of serum amyloid A2 mRNA promotes podocyte injury and inflammation by activating the NF-κB signaling pathway.
The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway.
Targeted mRNA Nanoparticles Ameliorate Blood-Brain Barrier Disruption Postischemic Stroke by Modulating Microglia Polarization.
Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.
Ageratina adenophora damages the rumen epithelium via inducing the expression of inflammatory factors in goats.
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium.
Dietary supplementation of benzoic acid and essential oils combination enhances intestinal resilience against LPS stimulation in weaned piglets.
A Platform for Testing the Biocompatibility of Implants: Silicone Induces a Proinflammatory Response in a 3D Skin Equivalent.
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.
Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox.
Levofloxacin alleviates blood-brain barrier disruption following cerebral ischemia and reperfusion via directly inhibiting A-FABP.
Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway.
Baitouweng decoction repairs the intestinal barrier in DSS-induced colitis mice via regulation of AMPK/mTOR-mediated autophagy.
Torreya grandis Kernel Oil Alleviates Loperamide-Induced Slow Transit Constipation via Up-Regulating the Colonic Expressions of Occludin/Claudin-1/ZO-1 and 5-HT3R/5-HT4R in BALB/c Mice.
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Gut microbiota dysbiosis and intestinal barrier impairment in diarrhea caused by cold drink and high-fat diet.
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Assessment of osteopontin as an early nephrotoxicity indicator in human renal proximal tubule cells and its application in evaluating lanthanum-induced nephrotoxicity.
Bone morphogenetic protein 4 thermosensitive hydrogel inhibits corneal neovascularization by repairing corneal epithelial apical junctional complexes.
peu-MIR2916-p3-enriched garlic exosomes ameliorate murine colitis by reshaping gut microbiota, especially by boosting the anti-colitic Bacteroides thetaiotaomicron.
Fluorene-9-bisphenol exposure damages the testis in mice through a novel mechanism of ferroptosis.
Electroacupuncture at ST36 modulates the intestinal microecology and may help repair the intestinal barrier in the rat model of severe acute pancreatitis.
(-)-Syringaresinol attenuates ulcerative colitis by improving intestinal epithelial barrier function and inhibiting inflammatory responses.
CpxAR two-component system contributes to virulence properties of Cronobacter sakazakii.
Microsporidia persistence in host impairs epithelial barriers and increases chances of inflammatory bowel disease.
The Effects of Yeast Protein on Gut Microbiota in Mice When Compared with Soybean Protein and Whey Protein Isolates.
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice.
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.
Cathepsin B-Responsive Programmed Brain Targeted Delivery System for Chemo-Immunotherapy Combination Therapy of Glioblastoma.
An Inulin-Type Fructan CP-A from Codonopsis pilosula Alleviated 5-Fluorouracil-Induced Intestinal Mucositis via the ERK/MLCK/MLC2 Pathway and Regulation of Gut Microbiota.
Intrauterine Growth Restriction Affects Colonic Barrier Function via Regulating the Nrf2/Keap1 and TLR4-NF-κB/ERK Pathways and Altering Colonic Microbiome and Metabolome Homeostasis in Growing-Finishing Pigs.
The microbial metabolite urolithin A reduces Clostridioides difficile toxin expression and toxin-induced epithelial damage.
A Mixture of Formic Acid, Benzoic Acid, and Essential Oils Enhanced Growth Performance via Modulating Nutrient Uptake, Mitochondrion Metabolism, and Immunomodulation in Weaned Piglets.
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
A single cell atlas of circulating immune cells involved in diabetic retinopathy.
Disrupting the gut microbiota/metabolites axis by Di-(2-ethylhexyl) phthalate drives intestinal inflammation via AhR/NF-κB pathway in mice.
Isofraxidin attenuates dextran sulfate sodium-induced ulcerative colitis through inhibiting pyroptosis by upregulating Nrf2 and reducing reactive oxidative species.
Melatonin alleviates necrotizing enterocolitis by reducing bile acid levels through the SIRT1/FXR signalling axis.
Irisin links Claudin-5 preservation and Mfn2-mediated mitochondrial dynamics to resist doxorubicin-induced cardiac endothelial damage.
Icariin Regulates EMT and Stem Cell-Like Character in Breast Cancer through Modulating lncRNA NEAT1/TGFβ/SMAD2 Signaling Pathway.
A multi-omics analysis of viral nucleic acid poly(I:C) responses to mammalian testicular stimulation.
Effects of Intestinal M Cells on Intestinal Barrier and Neuropathological Properties in an AD Mouse Model.
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Omega-3 Polyunsaturated Fatty Acids Alleviate Intestinal Barrier Dysfunction in Obstructive Jaundice Rats.
Fecal Microbiota Transplantation Alleviates Allergic Rhinitis via CD4(+) T Cell Modulation Through Gut Microbiota Restoration.
Auraptene Mitigates Colitis Induced by Dextran Sulfate Sodium in Mice by Regulating Specific Intestinal Flora and Repairing the Intestinal Barrier.
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
Nur77 as a novel regulator of Paneth cell differentiation and function.
Epimedii Folium decoction ameliorates osteoporosis in mice through NLRP3/caspase-1/IL-1β signalling pathway and gut-bone axis.
Seliciclib alleviates ulcerative colitis by inhibiting ferroptosis and improving intestinal inflammation.
Kidney-tonifying blood-activating decoction delays ventricular remodeling in rats with chronic heart failure by regulating gut microbiota and metabolites and p38 mitogen-activated protein kinase/p65 nuclear factor kappa-B/aquaporin-4 signaling pathway.
l-Theanine Prevents Colonic Damage via NF-κB/MAPK Signaling Pathways Induced by a High-Fat Diet in Rats.
Naringenin Alleviates Radiation-Induced Intestinal Injury by Inhibiting TRPV6 in Mice.
Protective Mechanism of Polysaccharide ORP-1 Isolated from Oudemansiella raphanipes against Age-Related Cognitive Decline through the Microbiota-Gut-Brain Axis.
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Protective effect of cilostazol on vascular injury in rats with acute ischemic stroke complicated with chronic renal failure.
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology.
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
L-theanine attenuates H(2)O(2)-induced inflammation and apoptosis in IPEC-J2 cells via inhibiting p38 MAPK signaling pathway.
Trilobatin attenuates cerebral ischaemia/reperfusion-induced blood-brain barrier dysfunction by targeting matrix metalloproteinase 9: The legend of a food additive.
A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease.
Alleviation of allergic asthma by rosmarinic acid via gut-lung axis.
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
Occludin and collagen IV degradation mediated by the T9SS effector SspA contributes to blood-brain barrier damage in ducks during Riemerella anatipestifer infection.
Faecalibacterium prausnitzii Supplementation Prevents Intestinal Barrier Injury and Gut Microflora Dysbiosis Induced by Sleep Deprivation.
Exploring the mechanism of Bushen Huoxue prescription in the treatment of early diabetic retinal edema from the perspective of inner blood-retinal barrier injury.
Canagliflozin protects against hyperglycemia-induced cerebrovascular injury by preventing blood-brain barrier (BBB) disruption via AMPK/Sp1/adenosine A2A receptor.
The Lactobacillus plantarum P-8 Probiotic Microcapsule Prevents DSS-Induced Colitis through Improving Intestinal Integrity and Reducing Colonic Inflammation in Mice.
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Bone-derived PDGF-BB enhances hippocampal non-specific transcytosis through microglia-endothelial crosstalk in HFD-induced metabolic syndrome.
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines.
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
miR-186-5p improves alveolar epithelial barrier function by targeting the wnt5a/β-catenin signaling pathway in sepsis-acute lung injury.
Acupuncture Extended the Thrombolysis Window by Suppressing Blood-Brain Barrier Disruption and Regulating Autophagy-Apoptosis Balance after Ischemic Stroke.
Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway.
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Long-Term Triclocarban Exposure Induced Enterotoxicity by Triggering Intestinal AhR-Mediated Inflammation and Disrupting Microbial Community in Mice.
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Microneedle array facilitates hepatic sinusoid construction in a large-scale liver-acinus-chip microsystem.
Caulerpa lentillifera improves ethanol-induced liver injury and modulates the gut microbiota in rats.
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
Panax notoginseng Alleviates Colitis via the Regulation of Gut Microbiota.
Functional Peptide-Modified Liposomes for siRNA Delivery to Rat Retinal Pigment Epithelium Cells: Effect of Peptide Sequences.
Butylphthalide improves brain damage induced by renal ischemia-reperfusion injury rats through Nrf2/HO-1 and NOD2/MAPK/NF-κB pathways.
A microfluidic thyroid-liver platform to assess chemical safety in humans.
Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle.
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Upregulated SSB Is Involved in Hepatocellular Carcinoma Progression and Metastasis through the Epithelial-Mesenchymal Transition, Antiapoptosis, and Altered ROS Level Pathway.
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
A hydrogel model of the human blood-brain barrier using differentiated stem cells.
Shensong Yangxin Capsule Reduces the Susceptibility of Arrhythmia in db/db Mice via Inhibiting the Inflammatory Response Induced by Endothelium Dysfunction.
Indole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Experimental Colitis Models.
Suppression of Wnt/β-catenin Signaling in PDAC via METTL16-mediated N6-methyladenosine Modification of DVL2.
Bacteroides acidifaciens and its derived extracellular vesicles improve DSS-induced colitis.
The immunity protection of intestine induced by pseudorabies virus del gI/gE/TK in piglets.
Leveraging a gene signature associated with disulfidptosis identified by machine learning to forecast clinical outcomes, immunological heterogeneities, and potential therapeutic targets within lower-grade glioma.
Fecal microbiota transplantation from HUC-MSC-treated mice alleviates acute lung injury in mice through anti-inflammation and gut microbiota modulation.
β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis.
Ultrasound-assisted intravesical botulinum toxin A delivery attenuates acetic acid-induced bladder hyperactivity in rats.
Mahuang Fuzi Xixin decoction ameliorates allergic rhinitis and repairs the airway epithelial barrier by modulating the lung microbiota dysbiosis.
Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness.
Intermittent fasting protects against food allergy in a murine model via regulating gut microbiota.
Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.
Circulating sepsis-related metabolite sphinganine could protect against intestinal damage during sepsis.
Whole intestinal microbiota transplantation is more effective than fecal microbiota transplantation in reducing the susceptibility of DSS-induced germ-free mice colitis.
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Zengshengping improves lung cancer by regulating the intestinal barrier and intestinal microbiota.
Establishment of a porcine bronchial epithelial cell line and its application to study innate immunity in the respiratory epithelium.
Network pharmacology and experimental study of phenolic acids in salvia miltiorrhiza bung in preventing ischemic stroke.
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury.
Wnt4 increases the thickness of the epidermis in burn wounds by activating canonical Wnt signalling and decreasing the cell junctions between epidermal cells.
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Efficient Therapy of Inflammatory Bowel Disease (IBD) with Highly Specific and Durable Targeted Ta(2) C Modified with Chondroitin Sulfate (TACS).
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury.
Lactiplantibacillus plantarum L47 and inulin alleviate enterotoxigenic Escherichia coli induced ileal inflammation in piglets by upregulating the levels of α-linolenic acid and 12,13-epoxyoctadecenoic acid.
Dietary emodin alleviates lipopolysaccharide-induced intestinal mucosal barrier injury by regulating gut microbiota in piglets.
Maslinic acid alleviates LPS-induced mice mastitis by inhibiting inflammatory response, maintaining the integrity of the blood-milk barrier and regulating intestinal flora.
Maintenance of airway epithelial barrier integrity via the inhibition of AHR/EGFR activation ameliorates chronic obstructive pulmonary disease using effective-component combination.
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
The panda-derived Lactiplantibacillus plantarum BSG201683 improves LPS-induced intestinal inflammation and epithelial barrier disruption in vitro.
A novel small molecule effectively ameliorates estrogen deficiency-induced osteoporosis by targeting the gut-bone signaling axis.
Gut microbiota modulate distal symmetric polyneuropathy in patients with diabetes.
The mechanism of simultaneous intake of Jujuboside A and B in the regulation of sleep at the hypothalamic level.
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Sea Conch Peptides Hydrolysate Alleviates DSS-Induced Colitis in Mice through Immune Modulation and Gut Microbiota Restoration.
Long-term PM2.5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models.
Multiomics reveal human umbilical cord mesenchymal stem cells improving acute lung injury via the lung-gut axis.
Fasting-mimicking diet alleviates inflammatory pain by inhibiting neutrophil extracellular traps formation and neuroinflammation in the spinal cord.
Pterostilbene alleviated cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction via inhibiting early endothelial cytoskeleton reorganization and late basement membrane degradation.
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Effects of DON on Mitochondrial Function, Endoplasmic Reticulum Stress, and Endoplasmic Reticulum Mitochondria Contact Sites in the Jejunum of Piglets.
Catalysis-Mediated Male Contraception through Black Phosphorus Nanosheets.
Cerebrospinal Fluid Pressure Reduction Induces Glia-Mediated Retinal Inflammation and Leads to Retinal Ganglion Cell Injury in Rats.
The therapeutic value of adipose-derived pericyte transplantation after intracerebral hemorrhage in rats.
Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans.
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Lactiplantibacillus plantarum Strain FLPL05 Promotes Longevity in Mice by Improving Intestinal Barrier.
3D Bioprinting of Neurovascular Tissue Modeling with Collagen-Based Low-Viscosity Composites.
Chlorogenic Acid Ameliorates Post-Infectious Irritable Bowel Syndrome by Regulating Extracellular Vesicles of Gut Microbes.
Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease.
Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism.
Dietary Betaine Supplementation Enhances Colonic Barrier Function through the Nrf2/Keap1 and TLR4-NF-κB/MAPK Signaling Pathways and Alters Colonic Microbiota in Bama Mini-Pigs.
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Atractylodes lancea Rhizome Polysaccharide Alleviates Immunosuppression and Intestinal Mucosal Injury in Mice Treated with Cyclophosphamide.
FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.
Effect of Cordyceps militaris Powder Prophylactic Supplementation on Intestinal Mucosal Barrier Impairment and Microbiota-Metabolites Axis in DSS-Injured Mice.
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis.
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Effects of Enteromorpha prolifera polysaccharides on growth performance, intestinal barrier function and cecal microbiota in yellow-feathered broilers under heat stress.
miR-379-5P INHIBITION ENHANCES INTESTINAL EPITHELIAL PROLIFERATION AND BARRIER FUNCTION RECOVERY AFTER ISCHEMIA/REPERFUSION BY TARGETING EIF4G2.
Role of SIRT2 in intestinal barrier under cold exposure.
The coexistence of aflatoxin M1 and ochratoxin A induced intestinal barrier disruption via the regulation of key differentially expressed microRNAs and long non-coding RNAs in BALB/c mice.
Nickel induces blood-testis barrier damage through ROS-mediated p38 MAPK pathways in mice.
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Dendrobium huoshanense Polysaccharide Improves High-Fat Diet Induced Liver Injury by Regulating the Gut-Liver Axis.
Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis.
Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury.
Refined Qingkailing protects the in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.
Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice.
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Cingulin regulates hair cell cuticular plate morphology and is required for hearing in human and mouse.
Quercetin Attenuates the Combined Effects of Zearalenone and Lipopolysaccharide on IPEC-J2 Cell Injury through Activating the Nrf2 Signaling Pathway.
Cadmium promotes colorectal cancer metastasis through EGFR/Akt/mTOR signaling cascade and dynamics.
Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.
Environmental cadmium exposure facilitates mammary tumorigenesis via reprogramming gut microbiota-mediated glutamine metabolism in MMTV-Erbb2 mice.
Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling.
Phlorizin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota and Inhibiting Ferroptosis.
Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice.
Bile Acid Derivatives Effectively Prevented High-Fat Diet-Induced Colonic Barrier Dysfunction.
Comparative study of cigarette smoke, Klebsiella pneumoniae, and their combination on airway epithelial barrier function in mice.
Interleukin-1β suppresses rabies virus infection by activating cGAS-STING pathway and compromising the blood-brain barrier integrity in mice.
Globoside and the mucosal pH mediate parvovirus B19 entry through the epithelial barrier.
Oral Metal-Free Melanin Nanozymes for Natural and Durable Targeted Treatment of Inflammatory Bowel Disease (IBD).
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.
Shengjiang Xiexin Decoction ameliorates antibiotic-associated diarrhea by altering the gut microbiota and intestinal metabolic homeostasis.
The protective effects of electroacupuncture on intestinal barrier lesions in IBS and UC model.
HCMV Infection Reduces Nidogen-1 Expression, Contributing to Impaired Neural Rosette Development in Brain Organoids.
Gut Microbiota from Short-Chain Chlorinated Paraffin-Exposed Mice Promotes Astrocyte Activation by Disrupting the Intestinal Tight Junction via Zonulin Upregulation.
Baicalin Attenuates H(2)O(2)-Induced Oxidative Stress by Regulating the AMPK/Nrf2 Signaling Pathway in IPEC-J2 Cells.
Calcitriol, an Active Form of Vitamin D3, Mitigates Skin Barrier Dysfunction in Atopic Dermatitis NC/Nga Mice.
Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine.
Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions.
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Therapeutic mechanisms of the medicine and food homology formula Xiao-Ke-Yin on glucolipid metabolic dysfunction revealed by transcriptomics, metabolomics and microbiomics in mice.
Hydrogen inhalation ameliorates hepatic inflammation and modulates gut microbiota in rats with high-fat diet-induced non-alcoholic fatty liver disease.
Bazedoxifene attenuates intestinal injury in sepsis by suppressing the NF-κB/NLRP3 signaling pathways.
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
HC067047 Ameliorates Sepsis-associated Encephalopathy by Suppressing Endoplasmic Reticulum Stress and Oxidative Stress-Induced Pyroptosis in the Hippocampi of Mice.
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
A novel model of subretinal edema induced by DL-alpha aminoadipic acid.
The Polo-Like Kinase 1-Mammalian Target of Rapamycin Axis Regulates Autophagy to Prevent Intestinal Barrier Dysfunction During Sepsis.
S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung.
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation.
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Cimifugin suppresses type 2 airway inflammation by binding to SPR and regulating its protein expression in a non-enzymatic manner.
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis.
p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.
Integration of metabolomics and transcriptomics to reveal ferroptosis is involved in Tripterygium wilfordii polyglycoside tablet-induced testicular injury.
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Alteration of gut microbiome and metabolome by Clostridium butyricum can repair the intestinal dysbiosis caused by antibiotics in mice.
Emblica officinalis mitigates intestinal toxicity of mice by modulating gut microbiota in lead exposure.
Highly stable fibronectin-mimetic-peptide-based supramolecular hydrogel to accelerate corneal wound healing.
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression.
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Tongqiao Huoxue Decoction ameliorates traumatic brain injury-induced gastrointestinal dysfunction by regulating CD36/15-LO/NR4A1 signaling, which fails when CD36 and CX3CR1 are deficient.
SRT1720 attenuates UVA-induced corneal endothelial damage via inhibition of oxidative stress and cellular apoptosis.
Dopamine D1 receptor agonist alleviates acute lung injury via modulating inflammatory responses in macrophages and barrier function in airway epithelial cells.
Spermidine protects intestinal mucosal barrier function in mice colitis via the AhR/Nrf2 and AhR/STAT3 signaling pathways.
YES-associated protein-regulated Smad7 worsen epithelial barrier injury of chronic sinusitis with nasal polyps.
Systematic assessment of hexavalent chromium-induced damage to male fertility and the preventive role of melatonin: a longitudinal study from the translational point of view.
Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice.
Non-Invasive and Label-Free On-Chip Impedance Monitoring of Heatstroke.
Fecal microbiota transplantation from sodium alginate-dosed mice and normal mice mitigates intestinal barrier injury and gut dysbiosis induced by antibiotics and cyclophosphamide.
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice.
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Polystyrene microplastics aggravate acute pancreatitis in mice.
MiR-26a-5p from HucMSC-derived extracellular vesicles inhibits epithelial mesenchymal transition by targeting Adam17 in silica-induced lung fibrosis.
Fluoride disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated RhoA/ROCK signaling and myosin light chain kinase.
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Effect of lonidamine derivatives on the inhibition of transformed cell area expansion.
Thioredoxin1 is a target to attenuate diabetes‑induced RPE cell dysfunction in human ARPE19 cells by alleviating oxidative stress.
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
Protective effects of melatonin on deoxynivalenol-induced oxidative stress and autophagy in IPEC-J2 cells.
Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases.
The ACE2 activator diminazene aceturate ameliorates colitis by repairing the gut-vascular barrier in mice.
Programmed cell death 10 increased blood-brain barrier permeability through HMGB1/TLR4 mediated downregulation of endothelial ZO-1 in glioblastoma.
Effects of the polypeptide from peanut meal mixed fermentation on lipid metabolism and intestinal flora of hyperlipidemic mice.
DSPE-PEG polymer enhanced berberine absorption specifically in the small intestine of rats through paracellular passway.
The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage.
Mn(3)O(4) Nanozyme Loaded Thermosensitive PDLLA-PEG-PDLLA Hydrogels for the Treatment of Inflammatory Bowel Disease.
Alginate oligosaccharide structures differentially affect DSS-induced colitis in mice by modulating gut microbiota.
Open source board based acoustofluidic transwells for reversible disruption of the blood-brain barrier for therapeutic delivery.
Mechanistic study for drug induced cholestasis using batch-fabricated 3D spheroids developed by agarose-stamping method.
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Hexavalent chromium disrupts the skin barrier by targeting ROS-mediated mitochondrial pathway apoptosis in keratinocytes.
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation.
Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury.
Apelin-13 prevents the effects of oxygen-glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT-mTOR signaling.
Metasilicate-based alkaline mineral water confers diarrhea resistance in maternally separated piglets via the microbiota-gut interaction.
Desulfovibrio desulfuricans aggravates atherosclerosis by enhancing intestinal permeability and endothelial TLR4/NF-κB pathway in Apoe (-/-) mice.
A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection.
FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
Effects of 6-Shogaol on Glucose Uptake and Intestinal Barrier Integrity in Caco-2 Cells.
Gut Bacterial Indole-3-acetic Acid Induced Immune Promotion Mediates Preventive Effects of Fu Brick Tea Polyphenols on Experimental Colitis.
Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions.
Intestinal epithelium penetration of liraglutide via cholic acid pre-complexation and zein/rhamnolipids nanocomposite delivery.
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota.
Involvement of gut-brain communication in arsenite-induced neurobehavioral impairments in adult male mice.
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Effects of Buyang Huanwu Decoction on Intestinal Barrier, Intestinal Flora, and Trimethylamine Oxide in Rats with Heart Failure.
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses.
Capsaicin shapes gut microbiota and pre-metastatic niche to facilitate cancer metastasis to liver.
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
PLK1 protects intestinal barrier function in sepsis: A translational research.
DHA-enriched phosphatidylserine alleviates high fat diet-induced jejunum injury in mice by modulating gut microbiota.
Lutein Prevents Liver Injury and Intestinal Barrier Dysfunction in Rats Subjected to Chronic Alcohol Intake.
Fecal microbiota transplantation attenuates Escherichia coli infected outgrowth by modulating the intestinal microbiome.
Small molecule compound K-7174 attenuates neuropsychiatric manifestations in lupus-prone mice.
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.
Effects of Houpo Mahuang Decoction on serum metabolism and TRPV1/Ca(2+)/TJs in asthma.
Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE-19 Cells.
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Toxicity assessment of organophosphate flame retardant triphenyl phosphate (TPHP) on intestines in mice.
Increased R-spondin 3 contributes to aerobic exercise-induced protection against renal vascular endothelial hyperpermeability and acute kidney injury.
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
The E3 ubiquitin ligase RNF31 mediates the development of ulcerative colitis by regulating NLRP3 inflammasome activation.
Ursodeoxycholic acid alleviates sepsis-induced lung injury by blocking PANoptosis via STING pathway.
Combined VEGF and bFGF loaded nanofiber membrane protects against neuronal injury and hypomyelination in a rat model of chronic cerebral hypoperfusion.
Protective effect of ethyl ferulate against hypoxic injury in retinal cells and retinal neovascularization in an oxygen-induced retinopathy model.
Dual-Targeted Nanoparticle-in-Microparticle System for Ulcerative Colitis Therapy.
Effects of enteral nutrition supplemented with octanoic acid on lipopolysaccharide-induced intestinal injury: role of peroxisome proliferator-activated receptor γ/STAT-1/myeloid differentiation factor 88 pathway.
Plasma-Activated Solutions Mitigates DSS-Induced Colitis via Restoring Redox Homeostasis and Reversing Microbiota Dysbiosis.
IGF2/IGF2R/Sting signaling as a therapeutic target in DSS-induced ulcerative colitis.
Lactobacillus acidophilus JYLA-126 Ameliorates Obesity-Associated Metabolic Disorders by Positively Regulating the AMPK Signaling Pathway Through the Gut-Liver Axis.
FGF21 alleviates endothelial mitochondrial damage and prevents BBB from disruption after intracranial hemorrhage through a mechanism involving SIRT6.
Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells.
Bacterial butyrate mediates the anti-atherosclerotic effect of silybin.
Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis and Ameliorates Colitis.
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP.
Clostridium butyricum and Clostridium tyrobutyricum: angel or devil for necrotizing enterocolitis?
Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients.
Gut microbiota-associated taurine metabolism dysregulation in a mouse model of Parkinson's disease.
Heat Stress-Induced Fetal Intrauterine Growth Restriction Is Associated with Elevated LPS Levels Along the Maternal Intestine-Placenta-Fetus Axis in Pregnant Mice.
The role of ROS-pyroptosis in PM(2.5) induced air-blood barrier destruction.
Maternal Selenium-Enriched Yeast Supplementation in Sows Enhances Offspring Growth and Antioxidant Status through the Nrf2/Keap1 Pathway.
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function.
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Succinate signaling attenuates high-fat diet-induced metabolic disturbance and intestinal barrier dysfunction.
Limosilactobacillus fermentum NCU003089 and Lactiplantibacillus plantarum NCU001261, two probiotics with inhibition of Escherichia coli and Cronobacter sakazakii translocation in vitro.
Sphingosine 1-phosphate receptor 1 regulates blood-brain barrier permeability in epileptic mice.
Triclocarban exposure aggravates dextran sulfate sodium-induced colitis by deteriorating the gut barrier function and microbial community in mice.
MiR-874-5p targets VDR/NLRP3 to reduce intestinal pyroptosis and improve intestinal barrier damage in sepsis.
Extracellular ATP accelerates cell death and decreases tight junction protein ZO-1 in hypoxic cochlear strial marginal cells in neonatal rats.
Arula-7 powder improves diarrhea and intestinal epithelial tight junction function associated with its regulation of intestinal flora in calves infected with pathogenic Escherichia coli O(1).
Mechanisms of Lung and Intestinal Microbiota and Innate Immune Changes Caused by Pathogenic Enterococcus Faecalis Promoting the Development of Pediatric Pneumonia.
Zinc-Rutin Particles Ameliorate DSS-Induced Acute and Chronic Colitis via Anti-inflammatory and Antioxidant Protection of the Intestinal Epithelial Barrier.
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis.
Dextran sulfate sodium-induced mild chronic colitis induced cognitive impairment accompanied by inhibition of neuronal maturation in adolescent mice.
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition.
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
Mechanisms of Qingyi Decoction in Severe Acute Pancreatitis-Associated Acute Lung Injury via Gut Microbiota: Targeting the Short-Chain Fatty Acids-Mediated AMPK/NF-κB/NLRP3 Pathway.
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice.
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Intranasal Delivery of Gene-Edited Microglial Exosomes Improves Neurological Outcomes after Intracerebral Hemorrhage by Regulating Neuroinflammation.
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Organotypic 3D Co-Culture of Human Pleura as a Novel In Vitro Model of Staphylococcus aureus Infection and Biofilm Development.
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis.
Huangkui capsule alleviates doxorubicin-induced proteinuria via protecting against podocyte damage and inhibiting JAK/STAT signaling.
Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver disease in high-fat diet-induced obese mice.
Cadmium-induced Sertoli Cell Injury Through p38-MAPK and Related Signaling Proteins-A Study by RNA Sequencing.
Lactational exposure to Deoxynivalenol causes mammary gland injury via inducing inflammatory response and impairing blood-milk barrier integrity in mice.
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Mitochondrial-targeting fluorescent small molecule IR-780 alleviates radiation-induced brain injury.
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Construction of a three-dimensional urothelium on-chip with barrier function based on urinary flow microenvironment.
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Kinase Activity Is Not Required for G Protein-Coupled Receptor Kinase 4 Restraining mTOR Signaling during Cilia and Kidney Development.
A leaky human colon model reveals uncoupled apical/basal cytotoxicity in early Clostridioides difficile toxin exposure.
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Selenoprotein W Ameliorates Experimental Colitis and Promotes Intestinal Epithelial Repair.
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Probiotic Lactobacillus rhamnosus GR-1 supplementation attenuates Pb-induced learning and memory deficits by reshaping the gut microbiota.
Lactobacillus fermentum CECT5716 Alleviates the Inflammatory Response in Asthma by Regulating TLR2/TLR4 Expression.
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Blue Light Induces RPE Cell Necroptosis, Which Can Be Inhibited by Minocycline.
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
Bacteroides fragilis strain ZY-312 promotes intestinal barrier integrity via upregulating the STAT3 pathway in a radiation-induced intestinal injury mouse model.
Tannic acid attenuates intestinal oxidative damage by improving antioxidant capacity and intestinal barrier in weaned piglets and IPEC-J2 cells.
Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.
Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Effects of Lipolysis-Stimulated Lipoprotein Receptor on Tight Junctions of Pancreatic Ductal Epithelial Cells in Hypertriglyceridemic Acute Pancreatitis.
Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway.
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
The effect of a fennel seed extract on the STAT signaling and intestinal barrier function.
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
The SARS-CoV-2 envelope protein disrupts barrier function in an in vitro human blood-brain barrier model.
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage.
Selenium-enriched Bifidobacterium longum DD98 effectively ameliorates dextran sulfate sodium-induced ulcerative colitis in mice.
Preventive effects of the Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple on chronic kidney disease rats via modulating the intestinal microbiota and enhancing the intestinal barrier.
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway.
Tryptophan Supplementation Enhances Intestinal Health by Improving Gut Barrier Function, Alleviating Inflammation, and Modulating Intestinal Microbiome in Lipopolysaccharide-Challenged Piglets.
Qingchang Wenzhong Decoction Prevents the Occurrence of Intestinal Tumors by Regulating Intestinal Microbiota and Gasdermin E.
Integrated analysis of inflammatory response subtype-related signature to predict clinical outcomes, immune status and drug targets in lower-grade glioma.
Effect of Tanshinone IIA on Gut Microbiome in Diabetes-Induced Cognitive Impairment.
Shenling Baizhu Powder Alleviates TNBS-Induced Colitis in Rats by Improving Intestinal Epithelial Permeability and Inhibiting Inflammation Through the TLR5/MyD88/NF-κB Pathway.
Transepithelial Secretion of Mucosal IgM Mediated by Polymeric Immunoglobulin Receptor of Flounder (Paralichthys olivaceus): In-Vivo and In-Vitro Evidence.
Artemisinin analog SM934 alleviates epithelial barrier dysfunction via inhibiting apoptosis and caspase-1-mediated pyroptosis in experimental colitis.
Human Fecal Microbiota Transplantation Reduces the Susceptibility to Dextran Sulfate Sodium-Induced Germ-Free Mouse Colitis.
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis.
Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis.
Liujunanwei decoction attenuates cisplatin-induced nausea and vomiting in a Rat-Pica model partially mediated by modulating the gut micsrobiome.
Correlation Analysis of Gut Microbiota and Serum Metabolome With Porphyromonas gingivalis-Induced Metabolic Disorders.
Effects of Zhishi Daozhi Decoction on the intestinal flora of nonalcoholic fatty liver disease mice induced by a high-fat diet.
Telomerase reverse transcriptase promotes angiogenesis in neonatal rats after hypoxic-ischemic brain damage.
A Platform for Co-Culture of Primary Human Colonic Epithelium With Anaerobic Probiotic Bacteria.
Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis.
Complement factor B inhibitor LNP023 improves lupus nephritis in MRL/lpr mice.
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells.
Exercise protects intestinal epithelial barrier from high fat diet- induced permeabilization through SESN2/AMPKα1/HIF-1α signaling.
Glutamine in suppression of lipopolysaccharide-induced piglet intestinal inflammation: The crosstalk between AMPK activation and mitochondrial function.
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions.
Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities.
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Protective Effects and Mechanism of a Novel Probiotic Strain Ligilactobacillus salivarius YL20 against Cronobacter sakazakii-Induced Necrotizing Enterocolitis In Vitro and In Vivo.
Effect and Mechanism of Pharmaceutical Excipients on Berberine to Alleviate Ulcerative Colitis via Regulating Gut Microbiota.
Phytic Acid Improves Hepatic Steatosis, Inflammation, and Oxidative Stress in High-Fat Diet (HFD)-Fed Mice by Modulating the Gut-Liver Axis.
Periplaneta americana Extract Pretreatment Alleviates Oxidative Stress and Inflammation and Increases the Abundance of Gut Akkermansia muciniphila in Diquat-Induced Mice.
Mo(3)Se(4) nanoparticle with ROS scavenging and multi-enzyme activity for the treatment of DSS-induced colitis in mice.
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Chromatin remodeler Znhit1 controls bone morphogenetic protein signaling in embryonic lung tissue branching.
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Rice Protein Peptides Alleviate Dextran Sulfate Sodium-Induced Colitis via the Keap1-Nrf2 Signaling Pathway and Regulating Gut Microbiota.
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Network Pharmacology Analysis and Experimental Validation of Kaempferol in the Treatment of Ischemic Stroke by Inhibiting Apoptosis and Regulating Neuroinflammation Involving Neutrophils.
Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema.
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice.
Restored intestinal integrity, nutrients transporters, energy metabolism, antioxidative capacity and decreased harmful microbiota were associated with IUGR piglet's catch-up growth before weanling.
Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice.
P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy.
Betaine Ameliorates Acute Sever Ulcerative Colitis by Inhibiting Oxidative Stress Induced Inflammatory Pyroptosis.
Suspended Collagen Hydrogels to Replicate Human Colonic Epithelial Cell Interactions with Immune Cells.
Metabolites of Latilactobacillus curvatus BYB3 and Indole Activate Aryl Hydrocarbon Receptor to Attenuate Lipopolysaccharide-Induced Intestinal Barrier Dysfunction.
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Neutrophil extracellular traps: A novel therapeutic target for intracranial hemorrhage.
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Xiaojianzhong decoction attenuates gastric mucosal injury by activating the p62/Keap1/Nrf2 signaling pathway to inhibit ferroptosis.
Luteolin alleviates ulcerative colitis by restoring the balance of NCR(-)ILC3/NCR(+)ILC3 to repairing impaired intestinal barrier.
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Hypoxia-Induced HIF-1α Expression Promotes Neurogenic Bladder Fibrosis via EMT and Pyroptosis.
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway.
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
FGF2 isoforms play distinct roles in tubular epithelial-to-mesenchymal transition in diabetic nephropathy.
Gestational PCB52 exposure induces hepatotoxicity and intestinal injury by activating inflammation in dam and offspring mice: A maternal and progeny study.
DHA-enriched phosphatidylcholine from Clupea harengus roes regulates the gut-liver axis to ameliorate high-fat diet-induced non-alcoholic fatty liver disease.
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury.
Galactooligosaccharides as a protective agent for intestinal barrier and its regulatory functions for intestinal microbiota.
Effect of dendrobium mixture in alleviating diabetic cognitive impairment associated with regulating gut microbiota.
Comparison of five diarrhea-predominant irritable bowel syndrome (IBS-D) rat models in the brain-gut-microbiota axis.
miR-145-5p targets MMP2 to protect brain injury in hypertensive intracerebral hemorrhage via inactivation of the Wnt/β-catenin signaling pathway.
Human branching cholangiocyte organoids recapitulate functional bile duct formation.
Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.
JAC4 Protects from X-ray Radiation-Induced Intestinal Injury by JWA-Mediated Anti-Oxidation/Inflammation Signaling.
Chromogranin A-derived peptide CGA47-66 protects against septic brain injury by reducing blood-brain barrier damage through the PI3K/AKT pathway.
Methamphetamine induces intestinal injury by altering gut microbiota and promoting inflammation in mice.
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
Phloretin Protects Bovine Rumen Epithelial Cells from LPS-Induced Injury.
Gestational exposure to GenX induces hepatic alterations by the gut-liver axis in maternal mice: A similar mechanism as PFOA.
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Astilbin from Smilax glabra Roxb. alleviates high-fat diet-induced metabolic dysfunction.
Diet composition affects long-term zearalenone exposure on the gut-blood-liver axis metabolic dysfunction in mice.
Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats.
Dietary ferulic acid and vanillic acid on inflammation, gut barrier function and growth performance in lipopolysaccharide-challenged piglets.
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats.
M1 macrophages impair tight junctions between endothelial cells after spinal cord injury.
Alterations in the expression level of visfatin in the lungs of piglets infected with PRRSV and its effect on PRRSV replication.
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Apple polyphenol extract modulates bile acid metabolism and gut microbiota by regulating the circadian rhythms in daytime-restricted high fat diet feeding C57BL/6 male mice.
Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway.
Bioactive triple peptide inhibits inflammasome activation to alleviate Salmonella-induced intestinal inflammation in mice via modulation of host defense and bacterial virulence.
Effect of TRAF6 in acute pancreatitis-induced intestinal barrier injury via TLR4/NF-κB signal pathway.
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Inhibition of galectin-3 ameliorates high-glucose-induced oxidative stress and inflammation in ARPE-19 cells.
Effects of dietary lycopene supplementation on intestinal morphology, antioxidant capability and inflammatory response in finishing pigs.
DEHP induces ferroptosis in testes via p38α-lipid ROS circulation and destroys the BTB integrity.
Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis.
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Aryl-hydrocarbon receptor-interacting protein regulates tumorigenic and metastatic properties of colorectal cancer cells driving liver metastasis.
Atractyloside-A ameliorates spleen deficiency diarrhea by interfering with TLR4/MyD88/NF-κB signaling activation and regulating intestinal flora homeostasis.
Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy.
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Longitudinal 16S rRNA Sequencing Reveals Relationships among Alterations of Gut Microbiota and Nonalcoholic Fatty Liver Disease Progression in Mice.
Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia.
Periodontitis may induce gut microbiota dysbiosis via salivary microbiota.
Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.
Analysis by transcriptomics and metabolomics for the proliferation inhibition and dysfunction through redox imbalance-mediated DNA damage response and ferroptosis in male reproduction of mice and TM4 Sertoli cells exposed to PM(2.5).
Oxidized PUFAs Increase Susceptibility of Mice to Salmonella Infection by Diminishing Host's Innate Immune Responses.
Burn Injury-Induced Extracellular Vesicle Production and Characteristics.
Breast Cancer Stem Cells-derived Extracellular Vesicles Affect PPARG Expression by Delivering MicroRNA-197 in Breast Cancer Cells.
Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis.
Protective role of casuarinin from Melastoma malabathricum against a mouse model of 5-fluorouracil-induced intestinal mucositis: Impact on inflammation and gut microbiota dysbiosis.
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia.
Human 2D Crypt Model for Assaying Intestinal Stem Cell Proliferation and Differentiation.
Neuroprotective Effects of Chlorogenic Acid in a Mouse Model of Intracerebral Hemorrhage Associated with Reduced Extracellular Matrix Metalloproteinase Inducer.
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Delayed administration of nafamostat mesylate inhibits thrombin-mediated blood-spinal cord barrier breakdown during acute spinal cord injury in rats.
Effect of Houpo-Mahuang Decoction on aggravated asthma induced by cigarette smoke and the expression of TRPA1 and tight junctions in mice.
Metformin protects against pericyte apoptosis and promotes neurogenesis through suppressing JNK p38 MAPK signalling activation in ischemia/reperfusion injury.
Bryodulcosigenin a natural cucurbitane-type triterpenoid attenuates dextran sulfate sodium (DSS)-induced colitis in mice.
Radiocontrast agent and intraductal pressure promote the progression of post-ERCP pancreatitis by regulating inflammatory response, cellular apoptosis, and tight junction integrity.
A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury.
Enterococcus faecium HDRsEf1 inhibits Lipopolysaccharide-induced downregulation of zona occludens -1 expression via toll-like receptor 2/4-mediated c-Jun N-terminal kinase/activator protein-1 signalling pathways.
Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis.
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Apple polyphenols improve intestinal barrier function by enhancing antioxidant capacity and suppressing inflammation in weaning piglets.
Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue.
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
Online Measurement System for Dynamic Flow Bioreactors to Study Barrier Integrity of hiPSC-Based Blood-Brain Barrier In Vitro Models.
De novo Lipogenesis in Astrocytes Promotes the Repair of Blood-Brain Barrier after Transient Cerebral Ischemia Through Interleukin-33.
Protective effects of polysaccharides from Atractylodes macrocephalae Koidz. against dextran sulfate sodium induced intestinal mucosal injury on mice.
Identifying distinct oxygen diffusivity through type I pneumocyte-like cell layers using microfluidic device.
Cordycepin, a major bioactive component of Cordyceps militaris, ameliorates diabetes-induced testicular damage through the Sirt1/Foxo3a pathway.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Oral delivery of decanoic acid conjugated plant protein shell incorporating hybrid nanosystem leverage intestinal absorption of polyphenols.
MicroRNA-582-5p regulates cell invasion in bladder cancer through targeting Forkhead Box G1.
Hyperglycemia induces corneal endothelial dysfunction through attenuating mitophagy.
Connexin32 ameliorates epithelial-to-mesenchymal-transition in diabetic renal tubular via inhibiting NOX4.
CRH/CRHR1 modulates cerebrovascular endothelial cell permeability in association with S1PR2 and S1PR3 under oxidative stress.
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Effects of Exopolysaccharides from Lactiplantibacillus plantarum JLAU103 on Intestinal Immune Response, Oxidative Stress, and Microbial Communities in Cyclophosphamide-Induced Immunosuppressed Mice.
Akkermansia muciniphila Ameliorates Acetaminophen-Induced Liver Injury by Regulating Gut Microbial Composition and Metabolism.
LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland.
LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice.
A Pilot Application of an iTRAQ-Based Proteomics Screen Estimates the Effects of Cigarette Smokers' Serum on RPE Cells With AMD High-Risk Alleles.
Effects of dietary dihydromyricetin supplementation on intestinal barrier and humoral immunity in growing-finishing pigs.
Hesperidin partly ameliorates the decabromodiphenyl ether-induced reproductive toxicity in pubertal mice.
Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.
Polysaccharide ORP-1 isolated from Oudemansiella raphanipes ameliorates age-associated intestinal epithelial barrier dysfunction in Caco-2 cells monolayer.
Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiation.
Dahuang Mudan decoction repairs intestinal barrier in chronic colitic mice by regulating the function of ILC3.
Glutathione Protects against Paraquat-Induced Oxidative Stress by Regulating Intestinal Barrier, Antioxidant Capacity, and CAR Signaling Pathway in Weaned Piglets.
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Effect of ginsenoside compound K on alleviating colitis via modulating gut microbiota.
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo.
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury.
Exploration of the mechanisms underlying the beneficial effect of Luo Tong formula on retinal function in diabetic rats via the "gut microbiota-inflammation-retina" axis.
Intermittent Fasting Alleviates Risk Markers in a Murine Model of Ulcerative Colitis by Modulating the Gut Microbiome and Metabolome.
The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response.
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Effects of chitosan oligosaccharides (COS) and FMT from COS-dosed mice on intestinal barrier function and cell apoptosis.
Microglia Regulate Blood-Brain Barrier Integrity via MiR-126a-5p/MMP9 Axis during Inflammatory Demyelination.
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis.
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Pyroptosis participates in PM(2.5)-induced air-blood barrier dysfunction.
Chitosan-modified Phellinus igniarius polysaccharide PLGA nanoparticles ameliorated inflammatory bowel disease.
Comparative Effects of Allulose, Fructose, and Glucose on the Small Intestine.
Tollip Orchestrates Macrophage Polarization to Alleviate Intestinal Mucosal Inflammation.
Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.
Protective effect of surface-layer proteins from four Lactobacillus strains on tumor necrosis factor-α-induced intestinal barrier dysfunction.
Neohesperidin Dihydrochalcone Ameliorates High-Fat Diet-Induced Glycolipid Metabolism Disorder in Rats.
Wumei pills attenuates 5-fluorouracil-induced intestinal mucositis through Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB pathway and microbiota regulation.
Stigmasterol attenuates hepatic steatosis in rats by strengthening the intestinal barrier and improving bile acid metabolism.
Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood-brain barrier disruption.
[Diethylhexyl phthalate induces anxiety-like behavior and learning and memory impairment in mice probably by damaging blood-brain barrier].
Ascorbic acid induces salivary gland function through TET2/acetylcholine receptor signaling in aging SAMP1/Klotho (-/-) mice.
Urolithin A attenuates arsenic-induced gut barrier dysfunction.
Curcumin Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice Through Regulating Gut Microbiota.
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.
Dietary ferulic acid supplementation improves intestinal antioxidant capacity and intestinal barrier function in weaned piglets.
Mesencephalic astrocyte-derived neurotrophic factor restores blood-brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway.
Gelsolin impairs barrier function in pancreatic ductal epithelial cells by actin filament depolymerization in hypertriglyceridemia-induced pancreatitis in vitro.
Interfering with alternatively activated macrophages by CSF-1R inhibition exerts therapeutic capacity on allergic airway inflammation.
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Late-onset hearing loss case associated with a heterozygous truncating variant of DIAPH1.
Industrially Produced Rice Protein Ameliorates Dextran Sulfate Sodium-Induced Colitis via Protecting the Intestinal Barrier, Mitigating Oxidative Stress, and Regulating Gut Microbiota.
Anemone chinensis Bunge aqueous enema alleviates dextran sulfate sodium-induced colitis via inhibition of inflammation and regulation of the colonic mucosal microbiota.
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.
Comparison of the effects of different calorie amounts of enteral nutrition in hypercatabolism associated with ghrelin-POMC in endotoxemic rats.
Sertoli cell and spermatogonial development in pigs.
Ubiquitin-Specific Protease 25 Aggravates Acute Pancreatitis and Acute Pancreatitis-Related Multiple Organ Injury by Destroying Tight Junctions Through Activation of The STAT3 Pathway.
Cathelicidin-WA Protects Against LPS-Induced Gut Damage Through Enhancing Survival and Function of Intestinal Stem Cells.
P16 (I NK 4a) Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice.
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Bovine Lactoferrin Protects Dextran Sulfate Sodium Salt Mice Against Inflammation and Impairment of Colonic Epithelial Barrier by Regulating Gut Microbial Structure and Metabolites.
Effects of Guava (Psidium guajava L.) Leaf Extract on the Metabolomics of Serum and Feces in Weaned Piglets Challenged by Escherichia coli.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via Activation of Peribiliary Glands through the Wnt Pathway.
Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota.
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1(-/-) Mice.
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Overexpression of 15-Hydroxyprostaglandin Dehydrogenase Inhibits A549 Lung Adenocarcinoma Cell Growth via Inducing Cell Cycle Arrest and Inhibiting Epithelial-Mesenchymal Transition.
Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.
Evaluation of the Anti-Aging Effects of a Probiotic Combination Isolated From Centenarians in a SAMP8 Mouse Model.
Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury.
Integrated Analysis of the Cecal Microbiome and Plasma Metabolomics to Explore NaoMaiTong and Its Potential Role in Changing the Intestinal Flora and Their Metabolites in Ischemic Stroke.
Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma.
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
The Panda-Derived Lactobacillus plantarum G201683 Alleviates the Inflammatory Response in DSS-Induced Panda Microbiota-Associated Mice.
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis.
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization.
Susceptibility of Human Airway Tissue Models Derived From Different Anatomical Sites to Bordetella pertussis and Its Virulence Factor Adenylate Cyclase Toxin.
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Neutrophil extracellular traps induce thrombogenicity in severe carotid stenosis.
The important roles and molecular mechanisms of annexin A(2) autoantibody in children with nephrotic syndrome.
Enteromorpha polysaccharide-zinc replacing prophylactic antibiotics contributes to improving gut health of weaned piglets.
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Magnetically-propelled fecal surrogates for modeling the impact of solid-induced shear forces on primary colonic epithelial cells.
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Mfsd2a overexpression alleviates vascular dysfunction in diabetic retinopathy.
Treatment of early brain injury after subarachnoid hemorrhage in the rat model by inhibiting p53-induced ferroptosis.
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure.
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Regulation of blood-brain barrier permeability by Salvinorin A via alleviating endoplasmic reticulum stress in brain endothelial cell after ischemia stroke.
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Improved epithelial cell-cell adhesion using molecular mobility of supramolecular surfaces.
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply.
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Seaweed polysaccharide mitigates intestinal barrier dysfunction induced by enterotoxigenic Escherichia coli through NF-κB pathway suppression in porcine intestinal epithelial cells.
Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting the intestinal barrier, mitigating oxidative stress and regulating the gut microbiota.
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation.
Neuroprotection of minocycline by inhibition of extracellular matrix metalloproteinase inducer expression following intracerebral hemorrhage in mice.
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Interleukin-9 promotes intestinal barrier injury of sepsis: a translational research.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.
Naringenin attenuates experimental autoimmune encephalomyelitis by protecting the intact of blood-brain barrier and controlling inflammatory cell migration.
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
l-Arabinose Attenuates Gliadin-Induced Food Allergy via Regulation of Th1/Th2 Balance and Upregulation of Regulatory T Cells in Mice.
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice.
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
A Microfluidic Multisize Spheroid Array for Multiparametric Screening of Anticancer Drugs and Blood-Brain Barrier Transport Properties.
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut-Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation.
Brain endothelial LRP1 maintains blood-brain barrier integrity.
Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNFα-promotes severe intestinal epithelial dysfunction.
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Xiao-Xu-Ming decoction prevented hemorrhagic transformation induced by acute hyperglycemia through inhibiting AGE-RAGE-mediated neuroinflammation.
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
Effects of cigarette smoke on the aggravation of ovalbumin-induced asthma and the expressions of TRPA1 and tight junctions in mice.
A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.
Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Roux-en-Y gastric bypass potentially improved intestinal permeability by regulating gut innate immunity in diet-induced obese mice.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Meningitic Escherichia coli α-hemolysin aggravates blood-brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling.
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling.
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Scratching damages tight junctions through the Akt-claudin 1 axis in atopic dermatitis.
CD151 Alleviates Early Blood-Brain Barrier Dysfunction After Experimental Focal Brain Ischemia in Rats.
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice.
A Comparison of Chitosan, Mesoporous Silica and Poly(lactic-co-glycolic) Acid Nanocarriers for Optimising Intestinal Uptake of Oral Protein Therapeutics.
Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.
Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.
Effects of Pinus massoniana pollen polysaccharides on intestinal microenvironment and colitis in mice.
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
Polystyrene microplastics induced male reproductive toxicity in mice.
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Antibiotic-induced microbiome depletion in adult mice disrupts blood-brain barrier and facilitates brain infiltration of monocytes after bone-marrow transplantation.
Punicalagin Prevents Hepatic Steatosis through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western Diet-Fed Mice.
First evidence of altered microbiota and intestinal damage and their link to absence epilepsy in a genetic animal model, the WAG/Rij rat.
Val-Val-Tyr-Pro protects against non-alcoholic steatohepatitis in mice by modulating the gut microbiota and gut-liver axis activation.
Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis.
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Induction of Epithelial-mesenchymal Transition in MDCK II Cells.
Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.
Galli gigeriae endothelium corneum: its intestinal barrier protective activity in vitro and chemical composition.
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Neutrophil extracellular traps induce a hypercoagulable state in glioma.
Salidroside protects against ventilation-induced lung injury by inhibiting the expression of matrix metalloproteinase-9.
Poly(ADP-ribose) polymerase inhibitor PJ34 protects against UVA-induced oxidative damage in corneal endothelium.
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Modified cyclodextrin-based nanoparticles mediated delivery of siRNA for huntingtin gene silencing across an in vitro BBB model.
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
Djulis Hull Improves Insulin Resistance and Modulates the Gut Microbiota in High-Fat Diet (HFD)-Induced Hyperglycaemia.
Dose-Dependent Relationship between Protection of Thioacetamide-Induced Acute Liver Injury and Hyperammonemia and Concentration of Lactobacillus salivarius Li01 in Mice.
Titanium dioxide nanoparticles perturb the blood-testis barrier via disruption of actin-based cell adhesive function.
Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice.
Intrahepatic cholestasis induced by α-naphthylisothiocyanate can cause gut-liver axis disorders.
LncRNA-MALAT1/miRNA-204-5p/Smad4 Axis Regulates Epithelial-Mesenchymal Transition, Proliferation and Migration of Lens Epithelial Cells.
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.
Effects of Dietary Supplementation of Algae-Derived Polysaccharides on Morphology, Tight Junctions, Antioxidant Capacity and Immune Response of Duodenum in Broilers under Heat Stress.
Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets.
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Multiple roles of FGF10 in the regulation of corneal endothelial wound healing.
Effects of the extract from peanut meal fermented with Bacillus natto and Monascus on lipid metabolism and intestinal barrier function of hyperlipidemic mice.
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Transwell Insert-Embedded Microfluidic Devices for Time-Lapse Monitoring of Alveolar Epithelium Barrier Function under Various Stimulations.
Impaired Colonic Contractility and Intestinal Permeability in Symptomatic Uncomplicated Diverticular Disease.
Exosomes derived from HeLa cells break down vascular integrity by triggering endoplasmic reticulum stress in endothelial cells.
Molecular mechanism mediating enteric bacterial translocation after severe burn: the role of cystic fibrosis transmembrane conductance regulator.
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation.
Teasaponin Ameliorates Murine Colitis by Regulating Gut Microbiota and Suppressing the Immune System Response.
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway.
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated Nucleotide Binding Oligomerization Domain-Like Receptor Protein 3 Inflammasome Activation in Retinopathy Induced by Hyperglycemia.
Screening, Safety Evaluation, and Mechanism of Two Lactobacillus fermentum Strains in Reducing the Translocation of Staphylococcus aureus in the Caco-2 Monolayer Model.
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Taurine Alleviates Intestinal Injury by Mediating Tight Junction Barriers in Diquat-Challenged Piglet Models.
Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells.
1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation In Vivo and In Vitro Model.
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.
Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae.
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids.
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening.
Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice.
Bioinformatics analysis of LINC01554 and its co‑expressed genes in hepatocellular carcinoma.
Protective effect of Lactobacillus salivarius Li01 on thioacetamide-induced acute liver injury and hyperammonaemia.
Anthocyanins decrease the internalization of TiO(2) nanoparticles into 3D Caco-2 spheroids.
Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.
Novel Pentapeptide Derived from Chicken by-Product Ameliorates DSS-Induced Colitis by Enhancing Intestinal Barrier Function via AhR-Induced Src Inactivation.
Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress.
Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway.
Effect of MicroRNA-126a-3p on Bone Marrow Mesenchymal Stem Cells Repairing Blood-brain Barrier and Nerve Injury after Intracerebral Hemorrhage.
Small airway remodeling in diabetic and smoking chronic obstructive pulmonary disease patients.
Exposure to nonylphenol in early life increases pro-inflammatory cytokines in the prefrontal cortex: Involvement of gut-brain communication.
Palmitic Acid Affects Intestinal Epithelial Barrier Integrity and Permeability In Vitro.
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions.
Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia.
A PTAL-miR-101-FN1 Axis Promotes EMT and Invasion-Metastasis in Serous Ovarian Cancer.
Jiao-tai-wan inhibits inflammation of the gut-brain-axis and attenuates cognitive impairment in insomnic rats.
Methamphetamine-induced alterations in intestinal mucosal barrier function occur via the microRNA-181c/ TNF-α/tight junction axis.
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way.
CD147 Promoted Epithelial Mesenchymal Transition in Airway Epithelial Cells Induced by Cigarette Smoke via Oxidative Stress Signaling Pathway.
microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.
ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch.
Ursodeoxycholic Acid Halts Pathological Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy.
Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease.
TBC1D20 Is Essential for Mouse Blood-Testis Barrier Integrity Through Maintaining the Epithelial Phenotype and Modulating the Maturation of Sertoli Cells.
Platelet regulates neuroinflammation and restores blood-brain barrier integrity in a mouse model of traumatic brain injury.
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Identification of differentially expressed genes and signaling pathways involved in endometriosis by integrated bioinformatics analysis.
Protective Effect of Naringin on In Vitro Gut-Vascular Barrier Disruption of Intestinal Microvascular Endothelial Cells Induced by TNF-α.
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion.
Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Melatonin protects the mouse testis against heat-induced damage.
Peripheral inflammation promotes brain tau transmission via disrupting blood-brain barrier.
Environmental lead exposure aggravates the progression of Alzheimer's disease in mice by targeting on blood brain barrier.
Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice.
Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats.
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Icariside II attenuates cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction in rats via regulating the balance of MMP9/TIMP1.
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice.
Polysaccharide from the seeds of Plantago asiatica L. alleviates nonylphenol induced intestinal barrier injury by regulating tight junctions in human Caco-2 cell line.
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain.
Salvianolic acid B protects against myocardial ischaemia-reperfusion injury in rats via inhibiting high mobility group box 1 protein expression through the PI3K/Akt signalling pathway.
A self-driven bioinspired nanovehicle by leukocyte membrane-hitchhiking for early detection and treatment of atherosclerosis.
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Metformin therapy confers cardioprotection against the remodeling of gap junction in tachycardia-induced atrial fibrillation dog model.
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice.
Protective effect of Dioscorea zingiberensis ethanol extract on the disruption of blood-testes barrier in high-fat diet/streptozotocin-induced diabetic mice by upregulating ZO-1 and Nrf2.
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage.
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis.
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage.
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Building a Thick Mucus Hydrogel Layer to Improve the Physiological Relevance of In Vitro Primary Colonic Epithelial Models.
Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds.
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis.
High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis.
Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking.
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Licochalcone A Protects the Blood-Milk Barrier Integrity and Relieves the Inflammatory Response in LPS-Induced Mastitis.
Administration of Akkermansia muciniphila Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1.
Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection.
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro.
The effects of c-Src kinase on EMT signaling pathway in human lens epithelial cells associated with lens diseases.
An in vitro intestinal platform with a self-sustaining oxygen gradient to study the human gut/microbiome interface.
The protective effect of selenium from heat stress-induced porcine small intestinal epithelial cell line (IPEC-J2) injury is associated with regulation expression of selenoproteins.
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Chitosan coating of zein-carboxymethylated short-chain amylose nanocomposites improves oral bioavailability of insulin in vitro and in vivo.
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
TIMM50 promotes tumor progression via ERK signaling and predicts poor prognosis of non-small cell lung cancer patients.
Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway.
Activation of SIRT1 ameliorates LPS-induced lung injury in mice via decreasing endothelial tight junction permeability.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Propofol Protects Lung Endothelial Barrier Function by Suppression of High-Mobility Group Box 1 (HMGB1) Release and Mitochondrial Oxidative Damage Catalyzed by HMGB1.
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Epidermal growth factor treatment has protective effects on the integrity of the blood-brain barrier against cerebral ischemia injury in bEnd3 cells.
Cold-inducible RNA-binding protein as a novel target to alleviate blood-brain barrier damage induced by cardiopulmonary bypass.
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Ethyl pyruvate protects against Salmonella intestinal infection in mice through down-regulation of pro-inflammatory factors and inhibition of TLR4/MAPK pathway.
Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells.
ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling.
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Connexin43 dephosphorylation at serine 282 is associated with connexin43-mediated cardiomyocyte apoptosis.
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system.
The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice.
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension.
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
LncRNA CRNDE promotes the epithelial-mesenchymal transition of hepatocellular carcinoma cells via enhancing the Wnt/β-catenin signaling pathway.
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Vanillin protects the blood-milk barrier and inhibits the inflammatory response in LPS-induced mastitis in mice.
Ezrin, a Membrane Cytoskeleton Cross-Linker Protein, as a Marker of Epithelial Damage in Asthma.
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota.
Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats.
The role of sphingosine 1-phosphate receptors on retinal pigment epithelial cells barrier function and angiogenic effects.
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
Oral delivery of a Lactococcus lactis strain secreting bovine lactoferricin-lactoferrampin alleviates the development of acute colitis in mice.
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice.
Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells.
Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy.
Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices.
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Butyrate Protects Mice Against Methionine-Choline-Deficient Diet-Induced Non-alcoholic Steatohepatitis by Improving Gut Barrier Function, Attenuating Inflammation and Reducing Endotoxin Levels.
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Effects of Dietary Serine Supplementation on Intestinal Integrity, Inflammation and Oxidative Status in Early-Weaned Piglets.
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway.
Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases.
Volatile Oil of Amomum villosum Inhibits Nonalcoholic Fatty Liver Disease via the Gut-Liver Axis.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
A novel SWIM domain protein ZSWIM5 inhibits the malignant progression of non-small-cell lung cancer.
ZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling.
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.
Fluoride altered rat's blood testis barrier by affecting the F-actin via IL-1α.
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
Autocrine transforming growth factor-β/activin A-Smad signaling induces hepatic progenitor cells undergoing partial epithelial-mesenchymal transition states.
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD.
Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood-Brain Barrier Permeability During Early Reperfusion in Stroke.
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD(+)-Mediated Epithelial-Mesenchymal Transition.
miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Effects of chronic noise exposure on the microbiome-gut-brain axis in senescence-accelerated prone mice: implications for Alzheimer's disease.
Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis.
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Tail Vein Infusion of Adipose-Derived Mesenchymal Stem Cell Alleviated Inflammatory Response and Improved Blood Brain Barrier Condition by Suppressing Endoplasmic Reticulum Stress in a Middle Cerebral Artery Occlusion Rat Model.
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Lipopolysaccharide Induces Subacute Cerebral Microhemorrhages with Involvement of Nitric Oxide Synthase in Rats.
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells.
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Paracellular tightness and the functional expression of efflux transporters P-gp and BCRP in bEnd3 cells.
Metformin Protects against LPS-Induced Intestinal Barrier Dysfunction by Activating AMPK Pathway.
Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury.
Potential Orphan Drug Therapy of Intravesical Liposomal Onabotulinumtoxin-A for Ketamine-Induced Cystitis by Mucosal Protection and Anti-inflammation in a Rat Model.
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense.
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Calycosin Suppresses Epithelial Derived Initiative Key Factors and Maintains Epithelial Barrier in Allergic Inflammation via TLR4 Mediated NF-κB Pathway.
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
Role of macrophage migration inhibitory factor (MIF) in the effects of oxidative stress on human retinal pigment epithelial cells.
The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-κB Inhibition.
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Administration of alpha-ketoglutarate improves epithelial restitution under stress injury in early-weaning piglets.
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Small Interfering RNA Targeting Dickkopf-1 Contributes to Neuroprotection After Intracerebral Hemorrhage in Rats.
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
Targeted deletion of Aqp4 promotes the formation of astrocytic gap junctions.
Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.
CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation.
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Phenotype transformation of immortalized NCM460 colon epithelial cell line by TGF-β1 is associated with chromosome instability.
A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells.
SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Knockout of BRD7 results in impaired spermatogenesis and male infertility.
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
Naturally Occurring Stilbenoid TSG Reverses Non-Alcoholic Fatty Liver Diseases via Gut-Liver Axis.
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism.
Par-3 modulates intestinal epithelial barrier function through regulating intracellular trafficking of occludin and myosin light chain phosphorylation.
The multi-targeted tyrosine kinase inhibitor vandetanib plays a bifunctional role in non-small cell lung cancer cells.
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Keratinocyte growth factor pretreatment prevents radiation-induced intestinal damage in a mouse model.
Increased epithelial permeability is the primary cause for bicarbonate loss in inflamed murine colon.
Keratinocyte growth factor improves epithelial structure and function in a mouse model of intestinal ischemia/reperfusion.
Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier.
Lu L, Zhu C, Xu J, Hu Y, Dai J, Wang S, Wei T
International journal of chronic obstructive pulmonary disease 2024;19:957-967
International journal of chronic obstructive pulmonary disease 2024;19:957-967
Trimethylamine N-oxide aggravates vascular permeability and endothelial cell dysfunction under diabetic condition: in vitro and in vivo study.
Jiang JY, Liu WM, Zhang QP, Ren H, Yao QY, Liu GQ, Lu PR
International journal of ophthalmology 2024;17(1):25-33
International journal of ophthalmology 2024;17(1):25-33
The Predictive Value of Serum DAO, HDC, and MMP8 for the Gastrointestinal Injury in the Early Stage of Acute Pancreatitis in an Animal Model and a Clinical Study.
Cheng R, Wang J, Wu Q, Peng P, Liao G, Luo X, Liang Z, Huang J, Qin M
International journal of general medicine 2024;17:1937-1948
International journal of general medicine 2024;17:1937-1948
TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway.
Zhao J, Chen C, Ge L, Jiang Z, Hu Z, Yin L
Frontiers in immunology 2024;15:1386780
Frontiers in immunology 2024;15:1386780
Btbd8 deficiency reduces susceptibility to colitis by enhancing intestinal barrier function and suppressing inflammation.
Yang X, He Z, Dong Q, Nai S, Duan X, Yu J, Zhao N, Du X, Chen L
Frontiers in immunology 2024;15:1382661
Frontiers in immunology 2024;15:1382661
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
He C, An Y, Shi L, Huang Y, Zhang H, Fu W, Wang M, Shan Z, Du Y, Xie J, Huang Z, Sun W, Zhao Y, Zhao B
Frontiers in pharmacology 2024;15:1371929
Frontiers in pharmacology 2024;15:1371929
SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.
Luo Y, Zhang Z, Ren J, Dou C, Wen J, Yang Y, Li X, Yan Z, Han Y
Frontiers in immunology 2024;15:1303356
Frontiers in immunology 2024;15:1303356
Interaction of Neisseria meningitidis carrier and disease isolates of MenB cc32 and MenW cc22 with epithelial cells of the nasopharyngeal barrier.
Peters S, Mohort K, Claus H, Stigloher C, Schubert-Unkmeir A
Frontiers in cellular and infection microbiology 2024;14:1389527
Frontiers in cellular and infection microbiology 2024;14:1389527
Nocardia rubra cell-wall skeleton mitigates whole abdominal irradiation-induced intestinal injury via regulating macrophage function.
Wu L, Chen L, Li H, Wang Y, Xu K, Chen W, Zhang A, Wang Y, Shi C
Burns & trauma 2024;12:tkad045
Burns & trauma 2024;12:tkad045
In vitro co-culture of Clostridium scindens with primary human colonic epithelium protects the epithelium against Staphylococcus aureus.
Wang H, Kim R, Wang Y, Furtado KL, Sims CE, Tamayo R, Allbritton NL
Frontiers in bioengineering and biotechnology 2024;12:1382389
Frontiers in bioengineering and biotechnology 2024;12:1382389
MMP-2-mediated Scube2 degradation promotes blood-brain barrier disruption by blocking the interaction between astrocytes and endothelial cells via inhibiting Sonic hedgehog pathway during early cerebral ischemia.
Shi T, Yue S, Xie C, Li X, Yang D, Hu L, Zhong Y, Zhang Y, Liu W
Journal of neurochemistry 2024 Sep;168(9):1877-1894
Journal of neurochemistry 2024 Sep;168(9):1877-1894
Cinnamaldehyde alleviates aspirin-induced gastric mucosal injury by regulating pi3k/akt pathway-mediated apoptosis, autophagy and ferroptosis.
Yan S, Bao S, Chen T, Chen J, Zhang J, Hu X, Liang Y, Zhou X, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155791
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155791
Intestinal NSD2 Aggravates Nonalcoholic Steatohepatitis Through Histone Modifications.
Zhang Y, Qiao Y, Li Z, Liu D, Jin Q, Guo J, Li X, Chen L, Liu L, Peng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402551
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402551
Gut microbiota dysbiosis contributes to α-synuclein-related pathology associated with C/EBPβ/AEP signaling activation in a mouse model of Parkinson's disease.
Fang X, Liu S, Muhammad B, Zheng M, Ge X, Xu Y, Kan S, Zhang Y, Yu Y, Zheng K, Geng D, Liu CF
Neural regeneration research 2024 Sep 1;19(9):2081-2088
Neural regeneration research 2024 Sep 1;19(9):2081-2088
Streptococcus salivarius ameliorates the destructive effect on the epithelial barrier by inhibiting the growth of Prevotella melaninogenica via metabolic acid production.
Zhu P, Shao R, Xu P, Zhao R, Zhao C, Fei J, He Y
Molecular oral microbiology 2024 Oct;39(5):407-416
Molecular oral microbiology 2024 Oct;39(5):407-416
Linagliptin's impact on lymphatic barrier and lymphangiogenesis in oral cancer with high glucose.
Wang H, She X, Xu Q, Zhou X, Tang Q, Wei H, Huang T, Liang F
Oral diseases 2024 Oct;30(7):4195-4208
Oral diseases 2024 Oct;30(7):4195-4208
Epigallocatechin gallate alleviated the in vivo toxicity of ZnO nanoparticles to mouse intestine.
Wang C, Huang C, Cao Y
Journal of applied toxicology : JAT 2024 May;44(5):686-698
Journal of applied toxicology : JAT 2024 May;44(5):686-698
Tongfu Lifei Decoction Attenuated Sepsis-Related Intestinal Mucosal Injury Through Regulating Th17/Treg Balance and Modulating Gut Microbiota.
Chen H, Yu Z, Qi Z, Huang X, Gao J
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2024 May;44(5):208-220
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2024 May;44(5):208-220
Carnosol alleviates sepsis-induced pulmonary endothelial barrier dysfunction by targeting nuclear factor erythroid2-related factor 2/sirtuin-3 signaling pathway to attenuate oxidative damage.
Li X, Wang S, Luo M, Wang M, Wu S, Liu C, Wang F, Li Y
Phytotherapy research : PTR 2024 May;38(5):2182-2197
Phytotherapy research : PTR 2024 May;38(5):2182-2197
Inhibition of piezo1 prevents chronic cerebral hypoperfusion-induced cognitive impairment and blood brain barrier disruption.
Xu F, Xin Q, Ren M, Shi P, Wang B
Neurochemistry international 2024 May;175:105702
Neurochemistry international 2024 May;175:105702
Prevotella melaninogenica disrupted oral epithelial barrier function via myosin light chain kinase.
Guo Y, Han W, He Y
Oral diseases 2024 May 8;
Oral diseases 2024 May 8;
Anchang Yuyang Decoction inhibits experimental colitis-related carcinogenesis by regulating PPAR signaling pathway and affecting metabolic homeostasis of host and microbiota.
Wei X, Liang J, Liu J, Dai Y, Leng X, Cheng Y, Chi L
Journal of ethnopharmacology 2024 May 23;326:117995
Journal of ethnopharmacology 2024 May 23;326:117995
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Sun Z, Xu Y, Shao B, Dang P, Hu S, Sun H, Chen C, Wang C, Liu J, Liu Y, Hu J
Journal for immunotherapy of cancer 2024 May 23;12(5)
Journal for immunotherapy of cancer 2024 May 23;12(5)
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Du Y, Xu Y, Guo X, Tan C, Zhu X, Liu G, Lyu X, Bei C
BMC cancer 2024 May 22;24(1):624
BMC cancer 2024 May 22;24(1):624
Silent information regulator 2 deficiency exacerbates chronic cold exposure-induced colonic injury and p65 activation in mice.
Guo J, Zhang H, Hu H, Zhao T, Ji H, Ma L, Lu J, Yuan J, Xu B
Gene 2024 May 20;907:148276
Gene 2024 May 20;907:148276
FGF17 protects cerebral ischemia reperfusion-induced blood-brain barrier disruption via FGF receptor 3-mediated PI3K/AKT signaling pathway.
Huang WT, Chen XJ, Lin YK, Shi JF, Li H, Wu HD, Jiang RL, Chen S, Wang X, Tan XX, Chen KY, Wang P
European journal of pharmacology 2024 May 15;971:176521
European journal of pharmacology 2024 May 15;971:176521
Puerarin Delays Mammary Gland Aging by Regulating Gut Microbiota and Inhibiting the p38MAPK Signaling Pathway.
Liu S, Hu H, Zhang M, Zhang Y, Geng R, Jin Y, Cao Y, Guo W, Liu J, Fu S
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
Journal of agricultural and food chemistry 2024 May 15;72(19):10879-10896
Metformin attenuates lung ischemia-reperfusion injury and necroptosis through AMPK pathway in type 2 diabetic recipient rats.
Liu T, Wei H, Zhang L, Ma C, Wei Y, Jiang T, Li W
BMC pulmonary medicine 2024 May 14;24(1):237
BMC pulmonary medicine 2024 May 14;24(1):237
An investigation into the HIF-dependent intestinal barrier protective mechanism of Qingchang Wenzhong decoction in ulcerative colitis management.
Yang MJ, Zhang YN, Qiao Z, Xu RY, Chen SM, Hu P, Yu HL, Pan Y, Cao J
Journal of ethnopharmacology 2024 May 10;325:117807
Journal of ethnopharmacology 2024 May 10;325:117807
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL3.
Wei YF, Li X, Zhao MR, Liu S, Min L, Zhu ST, Zhang ST, Xie SA
Cell communication and signaling : CCS 2024 May 10;22(1):263
Cell communication and signaling : CCS 2024 May 10;22(1):263
Minimally invasive vagus nerve stimulation modulates mast cell degranulation via the microbiota-gut-brain axis to ameliorate blood-brain barrier and intestinal barrier damage following ischemic stroke.
Wang Y, Tan Q, Pan M, Yu J, Wu S, Tu W, Li M, Jiang S
International immunopharmacology 2024 May 10;132:112030
International immunopharmacology 2024 May 10;132:112030
Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice.
Su Q, Su C, Zhang Y, Guo Y, Liu Y, Liu Y, Yong VW, Xue M
International immunopharmacology 2024 May 10;132:111962
International immunopharmacology 2024 May 10;132:111962
Ginsenoside CK Alleviates DSS-Induced IBD in Mice by Regulating Tryptophan Metabolism and Activating Aryl Hydrocarbon Receptor via Gut Microbiota Modulation.
Liu Y, Bai X, Wu H, Duan Z, Zhu C, Fu R, Fan D
Journal of agricultural and food chemistry 2024 May 1;72(17):9867-9879
Journal of agricultural and food chemistry 2024 May 1;72(17):9867-9879
Cuproptosis mediates copper-induced testicular spermatogenic cell death.
Zhang JY, Yu XJ, Li JJ, Xiao Y, Li GS, Yang F, Dong L
Asian journal of andrology 2024 May 1;26(3):295-301
Asian journal of andrology 2024 May 1;26(3):295-301
Narirutin Attenuates Cerebral Ischemia-Reperfusion Injury by Suppressing the TXNIP/NLRP3 Pathway.
Luo L, Wang S, Liu W, Zhang Z, Zhao M, Liu A
Neurochemical research 2024 Mar;49(3):692-705
Neurochemical research 2024 Mar;49(3):692-705
Inhibition of EphA4 reduces vasogenic edema after experimental stroke in mice by protecting the blood-brain barrier integrity.
Zhang S, Zhao J, Sha WM, Zhang XP, Mai JY, Bartlett PF, Hou ST
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Mar;44(3):419-433
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2024 Mar;44(3):419-433
Age-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.
Wang X, Luo Y, He S, Lu Y, Gong Y, Gao L, Mao S, Liu X, Jiang N, Pu Q, Du D, Shu Y, Hai S, Li S, Chen HN, Zhao Y, Xie D, Qi S, Lei P, Hu H, Xu H, Zhou ZG, Dong B, Zhang H, Zhang Y, Dai L
Nature aging 2024 Mar;4(3):414-433
Nature aging 2024 Mar;4(3):414-433
Cornuside protects against ischemic stroke in rats by suppressing the IL-17F/TRAF6/NF-κB pathway via the brain-gut axis.
Yan C, Liu Z, Xie W, Zhang T, Zhang J, Li G, Xu X, Ye L, Gong J
Experimental neurology 2024 Mar;373:114672
Experimental neurology 2024 Mar;373:114672
Engineered mesenchymal stem cell-derived small extracellular vesicles for diabetic retinopathy therapy through HIF-1α/EZH2/PGC-1α pathway.
Sun F, Sun Y, Wang X, Zhu J, Chen S, Yu Y, Zhu M, Xu W, Qian H
Bioactive materials 2024 Mar;33:444-459
Bioactive materials 2024 Mar;33:444-459
Selective HDAC6 inhibition protects against blood-brain barrier dysfunction after intracerebral hemorrhage.
Peng C, Wang Y, Hu Z, Chen C
CNS neuroscience & therapeutics 2024 Mar;30(3):e14429
CNS neuroscience & therapeutics 2024 Mar;30(3):e14429
Ageratina adenophora causes intestinal integrity damage in goats via the activation of the MLCK/ROCK signaling pathway.
Wang J, Wang S, Okyere SK, Wen J, Wang X, Huang R, Tang Z, Cao S, Deng J, Ren Z, Hu Y
Toxicon : official journal of the International Society on Toxinology 2024 Mar;240:107633
Toxicon : official journal of the International Society on Toxinology 2024 Mar;240:107633
Golden bifid treatment regulates gut microbiota and serum metabolites to improve myocardial dysfunction in cecal ligation and puncture-induced sepsis mice.
Wu R, Xu J, Zeng H, Fan Y, Li H, Peng T, Xiao F
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167049
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167049
Radix Bupleuri aqueous extract attenuates MK801-induced schizophrenia-like symptoms in mice: Participation of intestinal flora.
Yang P, Huang S, Luo Z, Zhou S, Zhang C, Zhu Y, Yang J, Li L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116267
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116267
Zinc lactate alleviates oxidative stress by modulating crosstalk between constitutive androstane receptor signaling pathway and gut microbiota profile in weaned piglets.
Tang W, Xiang X, Wang H, Zhou W, He L, Yin Y, Li T
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:23-33
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2024 Mar;16:23-33
AhR Activation Ameliorates Intestinal Barrier Damage in Immunostressed Piglets by Regulating Intestinal Flora and Its Metabolism.
Wu X, Zhang Y, Ji M, Yang W, Deng T, Hou G, Shi L, Xun W
Animals : an open access journal from MDPI 2024 Mar 4;14(5)
Animals : an open access journal from MDPI 2024 Mar 4;14(5)
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Fan W, Chen H, Li M, Fan X, Jiang F, Xu C, Wang Y, Wei W, Song J, Zhong D, Li G
Scientific reports 2024 Mar 4;14(1):5300
Scientific reports 2024 Mar 4;14(1):5300
Environmentally realistic dose of tire-derived metabolite 6PPD-Q exposure causes intestinal jejunum and ileum damage in mice via cannabinoid receptor-activated inflammation.
Yang Y, Sun N, Lv J, Chen H, Wang H, Xu J, Hu J, Tao L, Fang M, Huang Y
The Science of the total environment 2024 Mar 25;918:170679
The Science of the total environment 2024 Mar 25;918:170679
RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells.
Yang T, Xiang CG, Wang XH, Li QQ, Lei SY, Zhang KR, Ren J, Lu HM, Feng CL, Tang W
Cell death discovery 2024 Mar 23;10(1):152
Cell death discovery 2024 Mar 23;10(1):152
Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model.
Fu Y, Chen YS, Xia DY, Luo XD, Luo HT, Pan J, Ma WQ, Li JZ, Mo QY, Tu Q, Li MM, Zhao Y, Li Y, Huang YT, Chen ZX, Li ZJ, Bernard L, Dione M, Zhang YM, Miao K, Chen JY, Zhu SS, Ren J, Zhou LJ, Jiang XZ, Chen J, Lin ZP, Chen JP, Ye H, Cao QY, Zhu YW, Yang L, Wang X, Wang WC
NPJ biofilms and microbiomes 2024 Mar 20;10(1):25
NPJ biofilms and microbiomes 2024 Mar 20;10(1):25
Tangeretin Mitigates Trimethylamine Oxide Induced Arterial Inflammation by Disrupting Choline-Trimethylamine Conversion through Specific Manipulation of Intestinal Microflora.
Cao Y, Leng C, Lin K, Li Y, Zhou M, Zhou M, Shu X, Liu W
Molecules (Basel, Switzerland) 2024 Mar 16;29(6)
Molecules (Basel, Switzerland) 2024 Mar 16;29(6)
Selenomethionine Alleviates Deoxynivalenol-Induced Oxidative Injury in Porcine Intestinal Epithelial Cells Independent of MAPK Pathway Regulation.
Huang Z, Zhong H, Li T, Wang Z, Chen X, Zou T, You J, Chen J
Antioxidants (Basel, Switzerland) 2024 Mar 16;13(3)
Antioxidants (Basel, Switzerland) 2024 Mar 16;13(3)
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
Wei Q, Chen L, Luo W, Chen C, Shi Y, Xie J, Xie X, Luo HB
European journal of pharmacology 2024 Mar 15;967:176353
European journal of pharmacology 2024 Mar 15;967:176353
Trifluoperazine regulates blood-brain barrier permeability via the MLCK/p-MLC pathway to promote ischemic stroke recovery.
Zhang W, Chen S, Ma B, Ding Y, Liu X, He C, Wang B, Yuan M
iScience 2024 Mar 15;27(3):109156
iScience 2024 Mar 15;27(3):109156
Antidepressant fluoxetine alleviates colitis by reshaping intestinal microenvironment.
Teng S, Yang Y, Zhang W, Li X, Li W, Cui Z, Min L, Wu J
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Cell communication and signaling : CCS 2024 Mar 12;22(1):176
Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice.
Yuan Y, Deng S, Yang J, Shou Z, Wei C, Zhang L, Zhu F, Gao F, Liu X, Liu Y, Chen Q, Fan H
Aging 2024 Mar 11;16(6):5336-5353
Aging 2024 Mar 11;16(6):5336-5353
Achyranthes bidentata polysaccharide ameliorates type 2 diabetes mellitus by gut microbiota-derived short-chain fatty acids-induced activation of the GLP-1/GLP-1R/cAMP/PKA/CREB/INS pathway.
Xia T, He W, Luo Z, Wang K, Tan X
International journal of biological macromolecules 2024 Jun;270(Pt 2):132256
International journal of biological macromolecules 2024 Jun;270(Pt 2):132256
Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner.
Liu D, Hu L, Yang Y, Wang Y, Li Y, Su J, Wang G, Gong S
Immunology letters 2024 Jun;267:106853
Immunology letters 2024 Jun;267:106853
Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 pathway.
Long Y, Ang Y, Chen W, Wang Y, Shi M, Hu F, Zhou Q, Shi Y, Ge B, Peng Y, Yu W, Bao H, Li Q, Duan M, Gao J
Free radical biology & medicine 2024 Jun;218:132-148
Free radical biology & medicine 2024 Jun;218:132-148
Rosa laevigata Polysaccharides Ameliorate Dextran Sulfate Sodium-Induced Ulcerative Colitis of Beagles through Regulating Gut Microbiota.
Peng S, Lu X, Lin F, Mao N, Yu L, Zhu T, He J, Yang Y, Liu Z, Wang D
Chemistry & biodiversity 2024 Jun;21(6):e202302102
Chemistry & biodiversity 2024 Jun;21(6):e202302102
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota.
Bai X, Deng J, Duan Z, Fu R, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155577
Effect and mechanism of Prunella vulgaris L. extract on alleviating lipopolysaccharide-induced acute mastitis in protecting the blood-milk barrier and reducing inflammation.
Luo H, Li Y, Xie J, Xu C, Zhang Z, Li M, Xia B, Shi Z, Lin L
Journal of ethnopharmacology 2024 Jun 28;328:117998
Journal of ethnopharmacology 2024 Jun 28;328:117998
MyD88 Inhibition Attenuates Cerebral Ischemia-reperfusion Injury by Regulating the Inflammatory Response and Reducing Blood-brain Barrier Damage.
Jiang F, Xu C, Fan X, Yang S, Fan W, Li M, Song J, Wei W, Chen H, Zhong D, Li G
Neuroscience 2024 Jun 21;549:121-137
Neuroscience 2024 Jun 21;549:121-137
Astrocytes-Secreted WNT5B Disrupts the Blood-Brain Barrier Via ROR1/JNK/c-JUN Cascade During Meningitic Escherichia Coli Infection.
Qu X, Yang R, Tan C, Chen H, Wang X
Molecular neurobiology 2024 Jun 19;
Molecular neurobiology 2024 Jun 19;
Elucidating the modulatory role of dietary hydroxyproline on the integrity and functional performance of the intestinal barrier in early-weaned piglets: A comprehensive analysis of its interplay with the gut microbiota and metabolites.
Tang Z, Yang Y, Yang M, Jiang D, Ge Y, Zhang X, Liu H, Fu Q, Liu X, Yang Y, Wu Z, Ji Y
International immunopharmacology 2024 Jun 15;134:112268
International immunopharmacology 2024 Jun 15;134:112268
Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier.
Xu T, Yang J, Xu Y, Wang X, Gao X, Sun J, Zhou C, Huang Y
Neural regeneration research 2024 Jun 1;19(6):1344-1350
Neural regeneration research 2024 Jun 1;19(6):1344-1350
Development of an Inflamed High Throughput Stem-cell-based Gut Epithelium Model to Assess the Impact of Annexin A1.
Broering MF, Tocci S, Sout NT, Reutelingsperger C, Farsky SHP, Das S, Sayed IM
Stem cell reviews and reports 2024 Jul;20(5):1299-1310
Stem cell reviews and reports 2024 Jul;20(5):1299-1310
Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets.
Lu J, Liu G, Sun W, Jia G, Zhao H, Chen X, Wang J
The Journal of nutrition 2024 Jul;154(7):2087-2096
The Journal of nutrition 2024 Jul;154(7):2087-2096
Dietary emulsifier polysorbate 80 exposure accelerates age-related cognitive decline.
Zhang L, Yin Z, Liu X, Jin G, Wang Y, He L, Li M, Pang X, Yan B, Jia Z, Ma J, Wei J, Cheng F, Li D, Wang L, Han Z, Liu Q, Chen F, Cao H, Lei P
Brain, behavior, and immunity 2024 Jul;119:171-187
Brain, behavior, and immunity 2024 Jul;119:171-187
Narirutin mitigates dextrose sodium sulfate-induced colitis in mice by modulating intestinal flora.
Xu D, Liu D, Jiang N, Xie Y, He D, Cheng J, Liu J, Fu S, Hu G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155730
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155730
High correlated color temperature artificial lighting impairs retinal pigment epithelium integrity and chloride ion transport: A potential mechanism for choroidal thinning.
Zhang C, Jiao Q, Wang M, Zhu Z, Zhao J, Zheng Y
Biochemical and biophysical research communications 2024 Jul 23;718:150078
Biochemical and biophysical research communications 2024 Jul 23;718:150078
Neuroprotection of macamide in a mouse model of Alzheimer's disease involves Nrf2 signaling pathway and gut microbiota.
Xia N, Xu L, Huang M, Xu D, Li Y, Wu H, Mei Z, Yu Z
European journal of pharmacology 2024 Jul 15;975:176638
European journal of pharmacology 2024 Jul 15;975:176638
pH Sensitive Quercetin Nanoparticles Ameliorate DSS-Induced Colitis in Mice by Colon-Specific Delivery.
Wang L, Fu R, Meng Y, Liang J, Xue W, Hu H, Meng J, Zhang M
Molecular nutrition & food research 2024 Jan;68(2):e2300051
Molecular nutrition & food research 2024 Jan;68(2):e2300051
Addition of α-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems.
Yang ZX, Zhang Y, Wang Q, Zhang L, Liu YF, Zhang Y, Ren Y, Zhou C, Gao HW, Zhang NX, Feng LY
Acta pharmacologica Sinica 2024 Jan;45(1):36-51
Acta pharmacologica Sinica 2024 Jan;45(1):36-51
Quercetin ameliorates ulcerative colitis by activating aryl hydrocarbon receptor to improve intestinal barrier integrity.
Wang X, Xie X, Li Y, Xie X, Huang S, Pan S, Zou Y, Pan Z, Wang Q, Chen J, Zhou L, Luo X
Phytotherapy research : PTR 2024 Jan;38(1):253-264
Phytotherapy research : PTR 2024 Jan;38(1):253-264
Simultaneous ischemic regions targeting and BBB crossing strategy to harness extracellular vesicles for therapeutic delivery in ischemic stroke.
Liang HB, Chen X, Zhao R, Li SJ, Huang PS, Tang YH, Cui GH, Liu JR
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1037-1057
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1037-1057
Angiotensin-converting enzyme inhibitory peptide IVGFPAYGH protects against liver injury in mice fed a high‑sodium diet by inhibiting the RAS and remodeling gut microbial communities.
Zou L, Yu X, Cai K, Xu B, Chen C, Xiao G
International journal of biological macromolecules 2024 Jan;256(Pt 1):128265
International journal of biological macromolecules 2024 Jan;256(Pt 1):128265
Chitosan-coated artesunate protects against ulcerative colitis via STAT6-mediated macrophage M2 polarization and intestinal barrier protection.
Tao Y, Xu L, Liu X, Wang P, Wei S, Huang Y, Gu W, Bo R, Liu M, Yu J, Li J
International journal of biological macromolecules 2024 Jan;254(Pt 1):127680
International journal of biological macromolecules 2024 Jan;254(Pt 1):127680
PSD-95 inhibitor Tat-NR2B9c (NA-1) protects the integrity of the blood-brain barrier after transient middle artery occlusion in rats by downregulating matrix metalloprotease-9 and upregulating endothelial nitric oxide synthase.
Xu Y, Xu L, Xu C, Zhao M, Xu T, Xia L, Wu Y, Cao Y, Han Z
Brain research bulletin 2024 Jan;206:110836
Brain research bulletin 2024 Jan;206:110836
An Erythrocyte Membrane-Derived Nanosystem for Efficient Reversal of Endothelial Injury in Sepsis.
Zhang Y, Li J, Jing Q, Chen Z, Wang K, Sun C
Advanced healthcare materials 2024 Jan;13(3):e2302320
Advanced healthcare materials 2024 Jan;13(3):e2302320
The protective effects of icariin against testicular dysfunction in type 1 diabetic mice Via AMPK-mediated Nrf2 activation and NF-κB p65 inhibition.
Lu CS, Wu CY, Wang YH, Hu QQ, Sun RY, Pan MJ, Lu XY, Zhu T, Luo S, Yang HJ, Wang D, Wang HW
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155217
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155217
Cantharidin-induced toxic injury, oxidative stress, and autophagy attenuated by Astragalus polysaccharides in mouse testis.
Xiao Y, Liu R, Tang W, Yang C
Reproductive toxicology (Elmsford, N.Y.) 2024 Jan;123:108520
Reproductive toxicology (Elmsford, N.Y.) 2024 Jan;123:108520
Probiotic Clostridium butyricum ameliorates cognitive impairment in obesity via the microbiota-gut-brain axis.
Zheng M, Ye H, Yang X, Shen L, Dang X, Liu X, Gong Y, Wu Q, Wang L, Ge X, Fang X, Hou B, Zhang P, Tang R, Zheng K, Huang XF, Yu Y
Brain, behavior, and immunity 2024 Jan;115:565-587
Brain, behavior, and immunity 2024 Jan;115:565-587
Prevotella copri promotes vascular calcification via lipopolysaccharide through activation of NF-κB signaling pathway.
Hao QY, Yan J, Wei JT, Zeng YH, Feng LY, Que DD, Li SC, Guo JB, Fan Y, Ding YF, Zhang XL, Yang PZ, Gao JW, Li ZH
Gut microbes 2024 Jan-Dec;16(1):2351532
Gut microbes 2024 Jan-Dec;16(1):2351532
Meta-analysis identifying gut microbial biomarkers of Qinghai-Tibet Plateau populations and the functionality of microbiota-derived butyrate in high-altitude adaptation.
Zhao H, Sun L, Liu J, Shi B, Zhang Y, Qu-Zong CR, Dorji T, Wang T, Yuan H, Yang J
Gut microbes 2024 Jan-Dec;16(1):2350151
Gut microbes 2024 Jan-Dec;16(1):2350151
Renal macrophages monitor and remove particles from urine to prevent tubule obstruction.
He J, Cao Y, Zhu Q, Wang X, Cheng G, Wang Q, He R, Lu H, Weng Y, Mao G, Bao Y, Wang J, Liu X, Han F, Shi P, Shen XZ
Immunity 2024 Jan 9;57(1):106-123.e7
Immunity 2024 Jan 9;57(1):106-123.e7
Study on the Anti-Ulcerative Colitis Effect of Pseudo-Ginsenoside RT4 Based on Gut Microbiota, Pharmacokinetics, and Tissue Distribution.
Yu H, Wang C, Wu J, Wang Q, Liu H, Li Z, He S, Wang C, Liu J
International journal of molecular sciences 2024 Jan 9;25(2)
International journal of molecular sciences 2024 Jan 9;25(2)
Macrophage-derived MMP12 promotes fibrosis through sustained damage to endothelial cells.
Zhou X, Zhang C, Yang S, Yang L, Luo W, Zhang W, Zhang X, Chao J
Journal of hazardous materials 2024 Jan 5;461:132733
Journal of hazardous materials 2024 Jan 5;461:132733
Inhibition of circulating exosomes release with GW4869 mitigates severe acute pancreatitis-stimulated intestinal barrier damage through suppressing NLRP3 inflammasome-mediated pyroptosis.
Shao Y, Jiang Y, Wang J, Li H, Li C, Zhang D
International immunopharmacology 2024 Jan 5;126:111301
International immunopharmacology 2024 Jan 5;126:111301
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
Wang G, Li Z, Lin P, Zhang H, Wang Y, Zhang T, Wang H, Li H, Lin L, Zhao Y, Jia L, Chen Y, Ji H, Zhao W, Fu Z, Zhong Z
International immunopharmacology 2024 Jan 5;126:111183
International immunopharmacology 2024 Jan 5;126:111183
FTO-mediated m6A modification of serum amyloid A2 mRNA promotes podocyte injury and inflammation by activating the NF-κB signaling pathway.
Lang Y, Wang Q, Sheng Q, Lu S, Yang M, Kong Z, Gao Y, Fan X, Shen N, Wang R, Lv Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23409
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23409
The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway.
Zhou L, Yang Y, Fu X, Xia B, Li C, Lu C, Qi Y, Zhang H, Liu T
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117100
Journal of ethnopharmacology 2024 Jan 30;319(Pt 1):117100
Targeted mRNA Nanoparticles Ameliorate Blood-Brain Barrier Disruption Postischemic Stroke by Modulating Microglia Polarization.
Gao M, Li Y, Ho W, Chen C, Chen Q, Li F, Tang M, Fan Q, Wan J, Yu W, Xu X, Li P, Zhang XQ
ACS nano 2024 Jan 30;18(4):3260-3275
ACS nano 2024 Jan 30;18(4):3260-3275
Porcine Intestinal Mucosal Peptides Target Macrophage-Modulated Inflammation and Alleviate Intestinal Homeostasis in Dextrose Sodium Sulfate-Induced Colitis in Mice.
Wang Y, Xie Z, Wu X, Du L, Chong Z, Liu R, Han J
Foods (Basel, Switzerland) 2024 Jan 3;13(1)
Foods (Basel, Switzerland) 2024 Jan 3;13(1)
Ageratina adenophora damages the rumen epithelium via inducing the expression of inflammatory factors in goats.
Wang X, Wang J, Okyere SK, Huang R, Shao C, Yousif M, Deng J, Hu Y
Journal of animal science 2024 Jan 3;102
Journal of animal science 2024 Jan 3;102
Potential effects of sodium hyaluronate on constipation-predominant irritable bowel syndrome.
Cui L, Zou S, Liu J, Lv H, Li H, Zhang Z
International immunopharmacology 2024 Jan 25;127:111404
International immunopharmacology 2024 Jan 25;127:111404
Pro-inflammatory cytokines stimulate CFTR-dependent anion secretion in pancreatic ductal epithelium.
Angyal D, Groeneweg TA, Leung A, Desain M, Dulla K, de Jonge HR, Bijvelds MJC
Cellular & molecular biology letters 2024 Jan 23;29(1):18
Cellular & molecular biology letters 2024 Jan 23;29(1):18
Dietary supplementation of benzoic acid and essential oils combination enhances intestinal resilience against LPS stimulation in weaned piglets.
Cui C, Wei Y, Wang Y, Ma W, Zheng X, Wang J, Ma Z, Wu C, Chu L, Zhang S, Guan W, Chen F
Journal of animal science and biotechnology 2024 Jan 19;15(1):4
Journal of animal science and biotechnology 2024 Jan 19;15(1):4
A Platform for Testing the Biocompatibility of Implants: Silicone Induces a Proinflammatory Response in a 3D Skin Equivalent.
Nuwayhid R, Schulz T, Siemers F, Schreiter J, Kobbe P, Hofmann G, Langer S, Kurow O
Biomedicines 2024 Jan 19;12(1)
Biomedicines 2024 Jan 19;12(1)
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli.
Yang R, Wang X, Liu H, Chen J, Tan C, Chen H, Wang X
Cell communication and signaling : CCS 2024 Jan 17;22(1):44
Cell communication and signaling : CCS 2024 Jan 17;22(1):44
Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox.
Wang W, Yang T, Chen S, Liang L, Wang Y, Ding Y, Xiong W, Ye X, Guo Y, Shen S, Chen H, Chen J
Journal of biological engineering 2024 Jan 16;18(1):7
Journal of biological engineering 2024 Jan 16;18(1):7
Levofloxacin alleviates blood-brain barrier disruption following cerebral ischemia and reperfusion via directly inhibiting A-FABP.
Yang S, Xu D, Zhang D, Huang X, Li S, Wang Y, Lu J, Wang D, Guo ZN, Yang Y, Ye D, Wang Y, Xu A, Hoo RLC, Chang J
European journal of pharmacology 2024 Jan 15;963:176275
European journal of pharmacology 2024 Jan 15;963:176275
Effect of chronic noise exposure on glucose and lipid metabolism in mice via modulating gut microbiota and regulating CREB/CRTC2 and SREBP1/SCD pathway.
Wu S, Du W, Wu Z, Wen F, Zhong X, Huang X, Gu H, Wang J
Ecotoxicology and environmental safety 2024 Jan 15;270:115887
Ecotoxicology and environmental safety 2024 Jan 15;270:115887
Baitouweng decoction repairs the intestinal barrier in DSS-induced colitis mice via regulation of AMPK/mTOR-mediated autophagy.
Pan SM, Wang CL, Hu ZF, Zhang ML, Pan ZF, Zhou RY, Wang XJ, Huang SW, Li YY, Wang Q, Luo X, Zhou L, Hou JT, Chen B
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116888
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116888
Torreya grandis Kernel Oil Alleviates Loperamide-Induced Slow Transit Constipation via Up-Regulating the Colonic Expressions of Occludin/Claudin-1/ZO-1 and 5-HT3R/5-HT4R in BALB/c Mice.
Wang X, Guo R, Yu Z, Zikela L, Li J, Li S, Han Q
Molecular nutrition & food research 2024 Feb;68(4):e2300615
Molecular nutrition & food research 2024 Feb;68(4):e2300615
Alisol A Exerts Neuroprotective Effects Against HFD-Induced Pathological Brain Aging via the SIRT3-NF-κB/MAPK Pathway.
Lu T, Ding L, Zheng X, Li Y, Wei W, Liu W, Tao J, Xue X
Molecular neurobiology 2024 Feb;61(2):753-771
Molecular neurobiology 2024 Feb;61(2):753-771
Gut microbiota dysbiosis and intestinal barrier impairment in diarrhea caused by cold drink and high-fat diet.
Tian Y, Fu M, Su J, Yan M, Yu J, Wang C, Niu Z, Du Y, Hu X, Zheng J, Tao B, Gao Z, Chen J, Chen S, Lv G
Toxicology 2024 Feb;502:153728
Toxicology 2024 Feb;502:153728
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Li Z, Wang B, Tian L, Zheng B, Zhao X, Liu R
Inflammation 2024 Feb;47(1):376-389
Inflammation 2024 Feb;47(1):376-389
Assessment of osteopontin as an early nephrotoxicity indicator in human renal proximal tubule cells and its application in evaluating lanthanum-induced nephrotoxicity.
Chen Y, Xu F, Xiao X, Chi H, Lai Y, Lin X, Li Q, Song J, Wu W, Li Z, Yang X
Ecotoxicology and environmental safety 2024 Feb;271:115928
Ecotoxicology and environmental safety 2024 Feb;271:115928
Bone morphogenetic protein 4 thermosensitive hydrogel inhibits corneal neovascularization by repairing corneal epithelial apical junctional complexes.
Nan W, Shen S, Yang Y, Wu M, He Y, Zhang R, Cui X, Zhang Y
Materials today. Bio 2024 Feb;24:100944
Materials today. Bio 2024 Feb;24:100944
peu-MIR2916-p3-enriched garlic exosomes ameliorate murine colitis by reshaping gut microbiota, especially by boosting the anti-colitic Bacteroides thetaiotaomicron.
Wang X, Liu Y, Dong X, Duan T, Wang C, Wang L, Yang X, Tian H, Li T
Pharmacological research 2024 Feb;200:107071
Pharmacological research 2024 Feb;200:107071
Fluorene-9-bisphenol exposure damages the testis in mice through a novel mechanism of ferroptosis.
Feng Q, Liu Y, Zou L, Lei M, Zhu C, Xia W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Feb;184:114385
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Feb;184:114385
Electroacupuncture at ST36 modulates the intestinal microecology and may help repair the intestinal barrier in the rat model of severe acute pancreatitis.
Xu H, Wen Q, Hu H, Yang S, Lu L, Hu X, Li H, Huang X, Li N
Microbial biotechnology 2024 Feb;17(2):e14401
Microbial biotechnology 2024 Feb;17(2):e14401
(-)-Syringaresinol attenuates ulcerative colitis by improving intestinal epithelial barrier function and inhibiting inflammatory responses.
Liu Y, Wu J, Tan L, Li Z, Gao P, He S, Wang Q, Tang D, Wang C, Wang F, Li P, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155292
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155292
CpxAR two-component system contributes to virulence properties of Cronobacter sakazakii.
Jin T, Zhan X, Pang L, Peng B, Zhang X, Zhu W, Yang B, Xia X
Food microbiology 2024 Feb;117:104393
Food microbiology 2024 Feb;117:104393
Microsporidia persistence in host impairs epithelial barriers and increases chances of inflammatory bowel disease.
Jin J, Tang Y, Cao L, Wang X, Chen Y, An G, Zhang H, Pan G, Bao J, Zhou Z
Microbiology spectrum 2024 Feb 6;12(2):e0361023
Microbiology spectrum 2024 Feb 6;12(2):e0361023
The Effects of Yeast Protein on Gut Microbiota in Mice When Compared with Soybean Protein and Whey Protein Isolates.
Zhou X, Liang L, Sun B, Li K, Guo H, Zhang Y
Nutrients 2024 Feb 5;16(3)
Nutrients 2024 Feb 5;16(3)
Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice.
Yang YH, Chen C, Zheng Y, Wu ZJ, Zhou MQ, Liu XY, Miyashita K, Duan DL, Du L
Journal of agricultural and food chemistry 2024 Feb 28;72(8):4142-4154
Journal of agricultural and food chemistry 2024 Feb 28;72(8):4142-4154
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.
Jia L, Liu X, Liu X, Guan Q, Tian Y, Li J, Zhao P
Chinese medicine 2024 Feb 28;19(1):32
Chinese medicine 2024 Feb 28;19(1):32
Cathepsin B-Responsive Programmed Brain Targeted Delivery System for Chemo-Immunotherapy Combination Therapy of Glioblastoma.
Jiang S, Li W, Yang J, Zhang T, Zhang Y, Xu L, Hu B, Li Z, Gao H, Huang Y, Ruan S
ACS nano 2024 Feb 27;18(8):6445-6462
ACS nano 2024 Feb 27;18(8):6445-6462
An Inulin-Type Fructan CP-A from Codonopsis pilosula Alleviated 5-Fluorouracil-Induced Intestinal Mucositis via the ERK/MLCK/MLC2 Pathway and Regulation of Gut Microbiota.
Zhou J, Li D, Wang J, Cheng Z, Wang C, Zhang X, Xu X, Gao J
Pharmaceuticals (Basel, Switzerland) 2024 Feb 26;17(3)
Pharmaceuticals (Basel, Switzerland) 2024 Feb 26;17(3)
Intrauterine Growth Restriction Affects Colonic Barrier Function via Regulating the Nrf2/Keap1 and TLR4-NF-κB/ERK Pathways and Altering Colonic Microbiome and Metabolome Homeostasis in Growing-Finishing Pigs.
Xiong L, Azad MAK, Liu Y, Zhang W, Zhu Q, Hu C, You J, Kong X
Antioxidants (Basel, Switzerland) 2024 Feb 26;13(3)
Antioxidants (Basel, Switzerland) 2024 Feb 26;13(3)
The microbial metabolite urolithin A reduces Clostridioides difficile toxin expression and toxin-induced epithelial damage.
Ghosh S, Erickson D, Chua MJ, Collins J, Jala VR
mSystems 2024 Feb 20;9(2):e0125523
mSystems 2024 Feb 20;9(2):e0125523
A Mixture of Formic Acid, Benzoic Acid, and Essential Oils Enhanced Growth Performance via Modulating Nutrient Uptake, Mitochondrion Metabolism, and Immunomodulation in Weaned Piglets.
Wang X, Deng T, Zhou X, Chu L, Zeng X, Zhang S, Guan W, Chen F
Antioxidants (Basel, Switzerland) 2024 Feb 19;13(2)
Antioxidants (Basel, Switzerland) 2024 Feb 19;13(2)
Solobacterium moorei promotes the progression of adenomatous polyps by causing inflammation and disrupting the intestinal barrier.
Yu S, Wang X, Li Z, Jin D, Yu M, Li J, Li Y, Liu X, Zhang Q, Liu Y, Liu R, Wang X, Fang B, Zhang C, Wang R, Ren F
Journal of translational medicine 2024 Feb 17;22(1):169
Journal of translational medicine 2024 Feb 17;22(1):169
A single cell atlas of circulating immune cells involved in diabetic retinopathy.
Liao D, Fan W, Li N, Li R, Wang X, Liu J, Wang H, Hou S
iScience 2024 Feb 16;27(2):109003
iScience 2024 Feb 16;27(2):109003
Disrupting the gut microbiota/metabolites axis by Di-(2-ethylhexyl) phthalate drives intestinal inflammation via AhR/NF-κB pathway in mice.
Cheng X, Chen J, Guo X, Cao H, Zhang C, Hu G, Zhuang Y
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123232
Environmental pollution (Barking, Essex : 1987) 2024 Feb 15;343:123232
Isofraxidin attenuates dextran sulfate sodium-induced ulcerative colitis through inhibiting pyroptosis by upregulating Nrf2 and reducing reactive oxidative species.
He S, Zhang T, Wang YY, Yuan W, Li L, Li J, Yang YY, Wu DM, Xu Y
International immunopharmacology 2024 Feb 15;128:111570
International immunopharmacology 2024 Feb 15;128:111570
Melatonin alleviates necrotizing enterocolitis by reducing bile acid levels through the SIRT1/FXR signalling axis.
Lai J, Li F, Li H, Huang R, Ma F, Gu X, Cai Y, Huang D, Li S, Xiao S, Hao H
International immunopharmacology 2024 Feb 15;128:111360
International immunopharmacology 2024 Feb 15;128:111360
Irisin links Claudin-5 preservation and Mfn2-mediated mitochondrial dynamics to resist doxorubicin-induced cardiac endothelial damage.
He J, Hou L, Liu Q, Zhou R
Biochemical and biophysical research communications 2024 Feb 12;696:149501
Biochemical and biophysical research communications 2024 Feb 12;696:149501
Icariin Regulates EMT and Stem Cell-Like Character in Breast Cancer through Modulating lncRNA NEAT1/TGFβ/SMAD2 Signaling Pathway.
Song B, Wei F, Peng J, Wei X, Liu M, Nie Z, Ma Y, Peng T
Biological & pharmaceutical bulletin 2024 Feb 10;47(2):399-410
Biological & pharmaceutical bulletin 2024 Feb 10;47(2):399-410
A multi-omics analysis of viral nucleic acid poly(I:C) responses to mammalian testicular stimulation.
Yang D, Wu W, Lu Q, Mou Y, Chen W, Wan S, Zhang M, Wang C, Du X, Li N, Hua J
Stress biology 2024 Feb 1;4(1):9
Stress biology 2024 Feb 1;4(1):9
Effects of Intestinal M Cells on Intestinal Barrier and Neuropathological Properties in an AD Mouse Model.
Wu S, Hu L, Fu Y, Chen Y, Hu Z, Li H, Liu Z
Molecular neurobiology 2024 Dec;61(12):10006-10022
Molecular neurobiology 2024 Dec;61(12):10006-10022
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy.
Li X, Li J, Ji J, Li S, Yao X, Fan H, Yao R
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Journal of neurochemistry 2024 Dec;168(12):3982-4000
Omega-3 Polyunsaturated Fatty Acids Alleviate Intestinal Barrier Dysfunction in Obstructive Jaundice Rats.
Zhang C, Yin Z, Hu F, Lin X, Guan Q, Zhang F, Zhang X
Molecular biotechnology 2024 Aug;66(8):1954-1960
Molecular biotechnology 2024 Aug;66(8):1954-1960
Fecal Microbiota Transplantation Alleviates Allergic Rhinitis via CD4(+) T Cell Modulation Through Gut Microbiota Restoration.
Dong L, Tang Y, Wen S, He Y, Li F, Deng Y, Tao Z
Inflammation 2024 Aug;47(4):1278-1297
Inflammation 2024 Aug;47(4):1278-1297
Auraptene Mitigates Colitis Induced by Dextran Sulfate Sodium in Mice by Regulating Specific Intestinal Flora and Repairing the Intestinal Barrier.
Chen T, Jin N, Zhang Q, Li Z, Wang Q, Fang X
Inflammation 2024 Aug;47(4):1127-1141
Inflammation 2024 Aug;47(4):1127-1141
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
Xue W, Tianrun W, Jiaqi Y, Xin L, Ruxue D, Peng Z
Ecotoxicology and environmental safety 2024 Aug;281:116636
Ecotoxicology and environmental safety 2024 Aug;281:116636
Nur77 as a novel regulator of Paneth cell differentiation and function.
Cui C, Wang X, Zheng Y, Wu L, Li L, Wei H, Peng J
Mucosal immunology 2024 Aug;17(4):752-767
Mucosal immunology 2024 Aug;17(4):752-767
Epimedii Folium decoction ameliorates osteoporosis in mice through NLRP3/caspase-1/IL-1β signalling pathway and gut-bone axis.
Ma F, Zhang W, Zhou G, Qi Y, Mao HR, Chen J, Lu Z, Wu W, Zou X, Deng D, Lv S, Xiang N, Wang X
International immunopharmacology 2024 Aug 20;137:112472
International immunopharmacology 2024 Aug 20;137:112472
Seliciclib alleviates ulcerative colitis by inhibiting ferroptosis and improving intestinal inflammation.
Song Y, Song Q, Tan F, Wang Y, Li C, Liao S, Yu K, Mei Z, Lv L
Life sciences 2024 Aug 15;351:122794
Life sciences 2024 Aug 15;351:122794
Kidney-tonifying blood-activating decoction delays ventricular remodeling in rats with chronic heart failure by regulating gut microbiota and metabolites and p38 mitogen-activated protein kinase/p65 nuclear factor kappa-B/aquaporin-4 signaling pathway.
Xu R, Bi Y, He X, Zhang Y, Zhao X
Journal of ethnopharmacology 2024 Aug 10;330:118110
Journal of ethnopharmacology 2024 Aug 10;330:118110
l-Theanine Prevents Colonic Damage via NF-κB/MAPK Signaling Pathways Induced by a High-Fat Diet in Rats.
Fang C, Shen Y, Ma Z, Li Y, Zhang J, Liu C, Ye Y
Molecular nutrition & food research 2024 Apr;68(8):e2300797
Molecular nutrition & food research 2024 Apr;68(8):e2300797
Naringenin Alleviates Radiation-Induced Intestinal Injury by Inhibiting TRPV6 in Mice.
Ling Z, Wang Z, Chen L, Mao J, Ma D, Han X, Tian L, Zhu Q, Lu G, Yan X, Ding Y, Xiao W, Chen Y, Peng A, Yin X
Molecular nutrition & food research 2024 Apr;68(8):e2300745
Molecular nutrition & food research 2024 Apr;68(8):e2300745
Protective Mechanism of Polysaccharide ORP-1 Isolated from Oudemansiella raphanipes against Age-Related Cognitive Decline through the Microbiota-Gut-Brain Axis.
Ren YR, Cui WT, Jiang KL, He KQ, Lu YM, Chen Y, Pan WJ
Molecular nutrition & food research 2024 Apr;68(7):e2300739
Molecular nutrition & food research 2024 Apr;68(7):e2300739
Toll-like receptor 3 signaling drives enteric glial cells against dextran sulfate sodium-induced colitis in mice.
Zeng J, Lu QQ, Du XL, Yuan L, Yang XJ
Journal of molecular histology 2024 Apr;55(2):201-210
Journal of molecular histology 2024 Apr;55(2):201-210
Protective effect of cilostazol on vascular injury in rats with acute ischemic stroke complicated with chronic renal failure.
Sun R, Gu Q, Zhang X, Zeng R, Chen D, Yao J, Min J
Toxicological research 2024 Apr;40(2):189-202
Toxicological research 2024 Apr;40(2):189-202
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Liu X, Liu M, Chen L
Cell and tissue research 2024 Apr;396(1):103-117
Cell and tissue research 2024 Apr;396(1):103-117
Asiaticoside ameliorates DSS-induced colitis in mice by inhibiting inflammatory response, protecting intestinal barrier and regulating intestinal microecology.
Liu K, Yin Y, Shi C, Yan C, Zhang Y, Qiu L, He S, Li G
Phytotherapy research : PTR 2024 Apr;38(4):2023-2040
Phytotherapy research : PTR 2024 Apr;38(4):2023-2040
Anionic polysaccharides benefit the bioavailability of pork myofibrillar protein gels: Evidence from a perspective of protein absorption and metabolism.
Yu X, Nie W, Chen X, Zou LF, Xu BC, Chen CG
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
International journal of biological macromolecules 2024 Apr;263(Pt 1):130246
L-theanine attenuates H(2)O(2)-induced inflammation and apoptosis in IPEC-J2 cells via inhibiting p38 MAPK signaling pathway.
Li Z, Huang Z, Jia G, Zhao H, Liu G, Chen X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114561
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114561
Trilobatin attenuates cerebral ischaemia/reperfusion-induced blood-brain barrier dysfunction by targeting matrix metalloproteinase 9: The legend of a food additive.
Feng L, Li Y, Lin M, Xie D, Luo Y, Zhang Y, He Z, Gong Q, Zhun ZY, Gao J
British journal of pharmacology 2024 Apr;181(7):1005-1027
British journal of pharmacology 2024 Apr;181(7):1005-1027
A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease.
Saviano A, Schettino A, Iaccarino N, Mansour AA, Begum J, Marigliano N, Raucci F, Romano F, Riccardi G, Mitidieri E, d'Emmanuele di Villa Bianca R, Bello I, Panza E, Smimmo M, Vellecco V, Rimmer P, Cheesbrough J, Zhi Z, Iqbal TH, Pieretti S, D'Amore VM, Marinelli L, La Pietra V, Sorrentino R, Costa L, Caso F, Scarpa R, Cirino G, Randazzo A, Bucci M, McGettrick HM, Iqbal AJ, Maione F
Journal of autoimmunity 2024 Apr;144:103181
Journal of autoimmunity 2024 Apr;144:103181
Alleviation of allergic asthma by rosmarinic acid via gut-lung axis.
Guo HH, Han YX, Rong XJ, Shen Z, Shen HR, Kong LF, Guo YD, Li JZ, Xu B, Gao TL, Wang LL, Tie C, Jiang JD
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155470
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155470
Preparation and characterisation of baicalin magnesium and its protective effect in ulcerative colitis via gut microbiota-bile acid axis modulation.
Zhang L, Miao C, Wang Z, Guan X, Ma Y, Song J, Shen S, Song H, Li M, Liu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155416
Occludin and collagen IV degradation mediated by the T9SS effector SspA contributes to blood-brain barrier damage in ducks during Riemerella anatipestifer infection.
Chen Z, Zhu M, Liu D, Wu M, Niu P, Yu Y, Ding C, Yu S
Veterinary research 2024 Apr 9;55(1):49
Veterinary research 2024 Apr 9;55(1):49
Faecalibacterium prausnitzii Supplementation Prevents Intestinal Barrier Injury and Gut Microflora Dysbiosis Induced by Sleep Deprivation.
Wang X, Li Y, Wang X, Wang R, Hao Y, Ren F, Wang P, Fang B
Nutrients 2024 Apr 9;16(8)
Nutrients 2024 Apr 9;16(8)
Exploring the mechanism of Bushen Huoxue prescription in the treatment of early diabetic retinal edema from the perspective of inner blood-retinal barrier injury.
Li J, Guo X, Huang Y, Ren Y, Liang H, Xie X, Zhang M
Journal of ethnopharmacology 2024 Apr 6;323:117658
Journal of ethnopharmacology 2024 Apr 6;323:117658
Canagliflozin protects against hyperglycemia-induced cerebrovascular injury by preventing blood-brain barrier (BBB) disruption via AMPK/Sp1/adenosine A2A receptor.
Liu Z, Hua W, Jin S, Wang Y, Pang Y, Wang B, Zhao N, Song Y, Qi J
European journal of pharmacology 2024 Apr 5;968:176381
European journal of pharmacology 2024 Apr 5;968:176381
The Lactobacillus plantarum P-8 Probiotic Microcapsule Prevents DSS-Induced Colitis through Improving Intestinal Integrity and Reducing Colonic Inflammation in Mice.
Wang H, Sun Y, Ma X, Yang T, Wang F
Nutrients 2024 Apr 4;16(7)
Nutrients 2024 Apr 4;16(7)
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
Wang L, Yan M, Bu T, Wu X, Li L, Silvestrini B, Sun F, Cheng CY, Chen H
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Bone-derived PDGF-BB enhances hippocampal non-specific transcytosis through microglia-endothelial crosstalk in HFD-induced metabolic syndrome.
Liu G, Shu W, Chen Y, Fu Y, Fang S, Zheng H, Cheng W, Lin Q, Hu Y, Jiang N, Yu B
Journal of neuroinflammation 2024 Apr 29;21(1):111
Journal of neuroinflammation 2024 Apr 29;21(1):111
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Bu T, Wang L, Wu X, Gao S, Li X, Yun D, Yang X, Li L, Cheng CY, Sun F
Endocrinology 2024 Apr 29;165(6)
Endocrinology 2024 Apr 29;165(6)
Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines.
Zou J, Chen Q, He Y, Pan Y, Zhao H, Shi J, Wei Z, Yu S, Zhao Y, Han X, Lu Y, Chen W
BMC cancer 2024 Apr 23;24(1):507
BMC cancer 2024 Apr 23;24(1):507
The role of FPR2-mediated ferroptosis in formyl peptide-induced acute lung injury against endothelial barrier damage and protective effect of the mitochondria-derived peptide MOTS-c.
Wen Z, Fan J, Zhan F, Li X, Li B, Lu P, Yao X, Shen Z, Liu Z, Wang C, Li X, Jin W, Zhang X, Qi Y, Wang X, Song M
International immunopharmacology 2024 Apr 20;131:111911
International immunopharmacology 2024 Apr 20;131:111911
miR-186-5p improves alveolar epithelial barrier function by targeting the wnt5a/β-catenin signaling pathway in sepsis-acute lung injury.
Li M, Yang J, Wu Y, Ma X
International immunopharmacology 2024 Apr 20;131:111864
International immunopharmacology 2024 Apr 20;131:111864
Acupuncture Extended the Thrombolysis Window by Suppressing Blood-Brain Barrier Disruption and Regulating Autophagy-Apoptosis Balance after Ischemic Stroke.
Zhang Z, Lu T, Li S, Zhao R, Li H, Zhang X, Li Y, Xia Y, Ni G
Brain sciences 2024 Apr 19;14(4)
Brain sciences 2024 Apr 19;14(4)
Resveratrol Alleviates Zearalenone-Induced Intestinal Dysfunction in Mice through the NF-κB/Nrf2/HO-1 Signalling Pathway.
Xia S, Yan C, Gu J, Yuan Y, Zou H, Liu Z, Bian J
Foods (Basel, Switzerland) 2024 Apr 17;13(8)
Foods (Basel, Switzerland) 2024 Apr 17;13(8)
Dual RNA sequencing of Helicobacter pylori and host cell transcriptomes reveals ontologically distinct host-pathogen interaction.
Hu W, Zhai ZY, Huang ZY, Chen ZM, Zhou P, Li XX, Yang GH, Bao CJ, You LJ, Cui XB, Xia GL, Ou Yang MP, Zhang L, Wu WKK, Li LF, Zhang YX, Xiao ZG, Gong W
mSystems 2024 Apr 16;9(4):e0020624
mSystems 2024 Apr 16;9(4):e0020624
Long-Term Triclocarban Exposure Induced Enterotoxicity by Triggering Intestinal AhR-Mediated Inflammation and Disrupting Microbial Community in Mice.
Song Y, Lei H, Cao Z, Zhang C, Chen C, Wu M, Zhang H, Du R, Lijun L, Chen X, Zhang L
Chemical research in toxicology 2024 Apr 15;37(4):658-668
Chemical research in toxicology 2024 Apr 15;37(4):658-668
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system.
Peng Z, Ding YN, Yang ZM, Li XJ, Zhuang Z, Lu Y, Tang QS, Hang CH, Li W
Acta biomaterialia 2024 Apr 15;179:325-339
Acta biomaterialia 2024 Apr 15;179:325-339
Microneedle array facilitates hepatic sinusoid construction in a large-scale liver-acinus-chip microsystem.
Li S, Li C, Khan MI, Liu J, Shi Z, Gao D, Qiu B, Ding W
Microsystems & nanoengineering 2023;9:75
Microsystems & nanoengineering 2023;9:75
Caulerpa lentillifera improves ethanol-induced liver injury and modulates the gut microbiota in rats.
Lin KY, Yang HY, Yang SC, Chen YL, Watanabe Y, Chen JR
Current research in food science 2023;7:100546
Current research in food science 2023;7:100546
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
Hao Z, Zhang Z, Zhao Y, Wang D
The American journal of Chinese medicine 2023;51(2):355-372
The American journal of Chinese medicine 2023;51(2):355-372
Panax notoginseng Alleviates Colitis via the Regulation of Gut Microbiota.
Wang L, Shao L, Chen MY, Wang L, Yang P, Tan FB, Zhang W, Huang WH
The American journal of Chinese medicine 2023;51(1):107-127
The American journal of Chinese medicine 2023;51(1):107-127
Functional Peptide-Modified Liposomes for siRNA Delivery to Rat Retinal Pigment Epithelium Cells: Effect of Peptide Sequences.
Nishida S, Takashima Y, Endo K, Ishihara H
Biological & pharmaceutical bulletin 2023;46(10):1468-1478
Biological & pharmaceutical bulletin 2023;46(10):1468-1478
Butylphthalide improves brain damage induced by renal ischemia-reperfusion injury rats through Nrf2/HO-1 and NOD2/MAPK/NF-κB pathways.
Min J, Chen Q, Pan M, Liu T, Gu Q, Zhang D, Sun R
Renal failure 2023;45(2):2259234
Renal failure 2023;45(2):2259234
A microfluidic thyroid-liver platform to assess chemical safety in humans.
Kühnlenz J, Karwelat D, Steger-Hartmann T, Raschke M, Bauer S, Vural Ö, Marx U, Tinwell H, Bars R
ALTEX 2023;40(1):61-82
ALTEX 2023;40(1):61-82
Effects of a Macroporous Resin Extract of Dendrobium officinale Leaves in Rats with Hyperuricemia Induced by Anthropomorphic Unhealthy Lifestyle.
Li LZ, Wang XM, Feng XJ, Liu K, Li B, Zhu LJ, Xu WF, Zheng X, Dong YJ, He XL, Guan HR, Ding YY, Wu HS, Zhou CJ, Ye SY, Zhang BB, Lv GY, Chen SH
Evidence-based complementary and alternative medicine : eCAM 2023;2023:9990843
Evidence-based complementary and alternative medicine : eCAM 2023;2023:9990843
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Chen Y, Zhang H, Li Y, Wang T
Oxidative medicine and cellular longevity 2023;2023:8258354
Oxidative medicine and cellular longevity 2023;2023:8258354
Upregulated SSB Is Involved in Hepatocellular Carcinoma Progression and Metastasis through the Epithelial-Mesenchymal Transition, Antiapoptosis, and Altered ROS Level Pathway.
Wu H, Zhang Z, Han X, Zhang S, Zhang J, Han P, Zhang Y, Bai Y, Zhang Y
Oxidative medicine and cellular longevity 2023;2023:5207431
Oxidative medicine and cellular longevity 2023;2023:5207431
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
Zhou H, Zhang Q, Huang W, Zhou S, Wang Y, Zeng X, Wang H, Xie W, Kong H
International journal of biological sciences 2023;19(6):1875-1893
International journal of biological sciences 2023;19(6):1875-1893
A hydrogel model of the human blood-brain barrier using differentiated stem cells.
Singh NR, Gromnicova R, Brachner A, Kraev I, Romero IA, Neuhaus W, Male D
PloS one 2023;18(4):e0283954
PloS one 2023;18(4):e0283954
Shensong Yangxin Capsule Reduces the Susceptibility of Arrhythmia in db/db Mice via Inhibiting the Inflammatory Response Induced by Endothelium Dysfunction.
Zhang J, Li H, Wang D, Gu J, Hou Y, Wu Y
Drug design, development and therapy 2023;17:313-330
Drug design, development and therapy 2023;17:313-330
Indole-3-Aldehyde Reduces Inflammatory Responses and Restores Intestinal Epithelial Barrier Function Partially via Aryl Hydrocarbon Receptor (AhR) in Experimental Colitis Models.
Wang M, Guo J, Hart AL, Li JV
Journal of inflammation research 2023;16:5845-5864
Journal of inflammation research 2023;16:5845-5864
Suppression of Wnt/β-catenin Signaling in PDAC via METTL16-mediated N6-methyladenosine Modification of DVL2.
Yu L, Lu J, Xie N, Fang L, Chen S, Wu Y, Wang X, Li B
Journal of Cancer 2023;14(16):2964-2977
Journal of Cancer 2023;14(16):2964-2977
Bacteroides acidifaciens and its derived extracellular vesicles improve DSS-induced colitis.
Zheng C, Zhong Y, Xie J, Wang Z, Zhang W, Pi Y, Zhang W, Liu L, Luo J, Xu W
Frontiers in microbiology 2023;14:1304232
Frontiers in microbiology 2023;14:1304232
The immunity protection of intestine induced by pseudorabies virus del gI/gE/TK in piglets.
Zhang Y, Xu L, Tao Q, Liu Z, Wen J, Xu T, Lai S, Ai Y, Xu Z, Zhu L
Frontiers in microbiology 2023;14:1295524
Frontiers in microbiology 2023;14:1295524
Leveraging a gene signature associated with disulfidptosis identified by machine learning to forecast clinical outcomes, immunological heterogeneities, and potential therapeutic targets within lower-grade glioma.
Zhou Y, Cao Y, Liu W, Wang L, Kuang Y, Zhou Y, Chen Q, Cheng Z, Huang H, Zhang W, Jiang X, Wang B, Ren C
Frontiers in immunology 2023;14:1294459
Frontiers in immunology 2023;14:1294459
Fecal microbiota transplantation from HUC-MSC-treated mice alleviates acute lung injury in mice through anti-inflammation and gut microbiota modulation.
Hua F, Cui E, Lv L, Wang B, Li L, Lu H, Chen N, Chen W
Frontiers in microbiology 2023;14:1243102
Frontiers in microbiology 2023;14:1243102
β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis.
Zhang D, Ge F, Ji J, Li YJ, Zhang FR, Wang SY, Zhang SJ, Zhang DM, Chen M
Frontiers in pharmacology 2023;14:1218477
Frontiers in pharmacology 2023;14:1218477
Ultrasound-assisted intravesical botulinum toxin A delivery attenuates acetic acid-induced bladder hyperactivity in rats.
Liu Q, Gao Y, Cong H, Liao L
Frontiers in pharmacology 2023;14:1214145
Frontiers in pharmacology 2023;14:1214145
Mahuang Fuzi Xixin decoction ameliorates allergic rhinitis and repairs the airway epithelial barrier by modulating the lung microbiota dysbiosis.
Wei X, Ding M, Liang X, Zhang B, Tan X, Zheng Z
Frontiers in microbiology 2023;14:1206454
Frontiers in microbiology 2023;14:1206454
Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness.
Mu Y, Wei D, Yao L, Xu X, Li S, Cao R, Chen T, Zhang Z
Frontiers in physiology 2023;14:1198862
Frontiers in physiology 2023;14:1198862
Intermittent fasting protects against food allergy in a murine model via regulating gut microbiota.
Ma RX, Hu JQ, Fu W, Zhong J, Cao C, Wang CC, Qi SQ, Zhang XL, Liu GH, Gao YD
Frontiers in immunology 2023;14:1167562
Frontiers in immunology 2023;14:1167562
Probiotics treatment ameliorated mycophenolic acid-induced colitis by enhancing intestinal barrier function and improving intestinal microbiota dysbiosis in mice.
Zhang P, Chen J, Ming Y, Niu Y
Frontiers in microbiology 2023;14:1153188
Frontiers in microbiology 2023;14:1153188
Circulating sepsis-related metabolite sphinganine could protect against intestinal damage during sepsis.
Wang Z, Qi Y, Wang F, Zhang B, Jianguo T
Frontiers in immunology 2023;14:1151728
Frontiers in immunology 2023;14:1151728
Whole intestinal microbiota transplantation is more effective than fecal microbiota transplantation in reducing the susceptibility of DSS-induced germ-free mice colitis.
Yang Y, He J, Wang Y, Liang L, Zhang Z, Tan X, Tao S, Wu Z, Dong M, Zheng J, Zhang H, Feng S, Cheng W, Chen Q, Wei H
Frontiers in immunology 2023;14:1143526
Frontiers in immunology 2023;14:1143526
The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.
Wang F, Qian F, Zhang Q, Zhao J, Cen J, Zhang J, Zhou J, Luo M, Jia C, Rong X, Chu M
Frontiers in immunology 2023;14:1124118
Frontiers in immunology 2023;14:1124118
Zengshengping improves lung cancer by regulating the intestinal barrier and intestinal microbiota.
Sun E, Meng X, Kang Z, Gu H, Li M, Tan X, Feng L, Jia X
Frontiers in pharmacology 2023;14:1123819
Frontiers in pharmacology 2023;14:1123819
Establishment of a porcine bronchial epithelial cell line and its application to study innate immunity in the respiratory epithelium.
Fukuyama K, Zhuang T, Toyoshi E, Raya Tonetti F, Saha S, Zhou B, Ikeda-Ohtsubo W, Nishiyama K, Aso H, Villena J, Kitazawa H
Frontiers in immunology 2023;14:1117102
Frontiers in immunology 2023;14:1117102
Network pharmacology and experimental study of phenolic acids in salvia miltiorrhiza bung in preventing ischemic stroke.
Liu C, Du L, Zhang S, Wang H, Kong L, Du G
Frontiers in pharmacology 2023;14:1108518
Frontiers in pharmacology 2023;14:1108518
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
Ding S, Cheng Y, Azad MAK, Dong H, He J, Huang P, Kong X
Frontiers in immunology 2023;14:1104837
Frontiers in immunology 2023;14:1104837
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Ma P, Huang N, Tang J, Zhou Z, Xu J, Chen Y, Zhang M, Huang Q, Cheng Y
Frontiers in pharmacology 2023;14:1098228
Frontiers in pharmacology 2023;14:1098228
Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury.
Jia J, Deng J, Jin H, Yang J, Nan D, Yu Z, Yu W, Shen Z, Lu Y, Liu R, Wang Z, Qu X, Qiu D, Yang Z, Huang Y
Frontiers in pharmacology 2023;14:1084564
Frontiers in pharmacology 2023;14:1084564
Wnt4 increases the thickness of the epidermis in burn wounds by activating canonical Wnt signalling and decreasing the cell junctions between epidermal cells.
Xiang F, Wang P, Gong H, Luo J, Zhou X, Zhan C, Hu T, Wang M, Xing Y, Guo H, Luo G, Li Y
Burns & trauma 2023;11:tkac053
Burns & trauma 2023;11:tkac053
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ge L, Wang K, Lin H, Tao E, Xia W, Wang F, Mao C, Feng Y
Frontiers in bioengineering and biotechnology 2023;11:1129538
Frontiers in bioengineering and biotechnology 2023;11:1129538
Efficient Therapy of Inflammatory Bowel Disease (IBD) with Highly Specific and Durable Targeted Ta(2) C Modified with Chondroitin Sulfate (TACS).
Song X, Huang Q, Yang Y, Ma L, Liu W, Ou C, Chen Q, Zhao T, Xiao Z, Wang M, Jiang Y, Yang Y, Zhang J, Nan Y, Wu W, Ai K
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(36):e2301585
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(36):e2301585
Apelin-Overexpressing Neural Stem Cells in Conjunction with a Silk Fibroin Nanofiber Scaffold for the Treatment of Traumatic Brain Injury.
Li T, Tang Q, Xu J, Ye X, Chen K, Zhong J, Zhu J, Lu S, Zhu T
Stem cells and development 2023 Sep;32(17-18):539-553
Stem cells and development 2023 Sep;32(17-18):539-553
Mitophagy contributes to zinc-induced ferroptosis in porcine testis cells.
Li Q, Yang Q, Guo P, Feng Y, Wang S, Guo J, Tang Z, Yu W, Liao J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Sep;179:113950
Inhibition of autophagy and RIP1/RIP3/MLKL-mediated necroptosis by edaravone attenuates blood spinal cord barrier disruption following spinal cord injury.
Xu B, Fang J, Wang J, Jin X, Liu S, Song K, Wang P, Liu J, Liu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115165
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115165
Lactiplantibacillus plantarum L47 and inulin alleviate enterotoxigenic Escherichia coli induced ileal inflammation in piglets by upregulating the levels of α-linolenic acid and 12,13-epoxyoctadecenoic acid.
Cui L, Zeng H, Hou M, Li Z, Mu C, Zhu W, Hang S
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:370-382
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:370-382
Dietary emodin alleviates lipopolysaccharide-induced intestinal mucosal barrier injury by regulating gut microbiota in piglets.
Xun W, Ji M, Ma Z, Deng T, Yang W, Hou G, Shi L, Cao T
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:152-162
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2023 Sep;14:152-162
Maslinic acid alleviates LPS-induced mice mastitis by inhibiting inflammatory response, maintaining the integrity of the blood-milk barrier and regulating intestinal flora.
Li K, Ran X, Zeng Y, Li S, Hu G, Wang X, Li Y, Yang Z, Liu J, Fu S
International immunopharmacology 2023 Sep;122:110551
International immunopharmacology 2023 Sep;122:110551
Maintenance of airway epithelial barrier integrity via the inhibition of AHR/EGFR activation ameliorates chronic obstructive pulmonary disease using effective-component combination.
Wei Y, Liu X, Jiang Y, Guan Q, Tian Y, Li J, Zhao P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154980
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154980
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
Chen J, Liu X, Bi R, Liu P, Gong W
Neuroreport 2023 Sep 6;34(13):670-676
Neuroreport 2023 Sep 6;34(13):670-676
The panda-derived Lactiplantibacillus plantarum BSG201683 improves LPS-induced intestinal inflammation and epithelial barrier disruption in vitro.
Zhou Y, Duan L, Zeng Y, Song X, Pan K, Niu L, Pu Y, Li J, Khalique A, Fang J, Jing B, Zeng D, Shen B, Ni X
BMC microbiology 2023 Sep 6;23(1):249
BMC microbiology 2023 Sep 6;23(1):249
A novel small molecule effectively ameliorates estrogen deficiency-induced osteoporosis by targeting the gut-bone signaling axis.
Chen C, Lei H, Zhao Y, Hou Y, Zheng H, Zhang C, Cao Z, Wu F, Chen G, Song Y, Zhang C, Zhou J, Lu Y, Xie D, Zhang L
European journal of pharmacology 2023 Sep 5;954:175868
European journal of pharmacology 2023 Sep 5;954:175868
Gut microbiota modulate distal symmetric polyneuropathy in patients with diabetes.
Yang J, Yang X, Wu G, Huang F, Shi X, Wei W, Zhang Y, Zhang H, Cheng L, Yu L, Shang J, Lv Y, Wang X, Zhai R, Li P, Cui B, Fang Y, Deng X, Tang S, Wang L, Yuan Q, Zhao L, Zhang F, Zhang C, Yuan H
Cell metabolism 2023 Sep 5;35(9):1548-1562.e7
Cell metabolism 2023 Sep 5;35(9):1548-1562.e7
The mechanism of simultaneous intake of Jujuboside A and B in the regulation of sleep at the hypothalamic level.
Wang W, Wang Y, Pei H, Li M, Zhu A, Du R, Peng GJ
Aging 2023 Sep 5;15(18):9426-9437
Aging 2023 Sep 5;15(18):9426-9437
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Lei P, Li Z, Hua Q, Song P, Gao L, Zhou L, Cai Q
International journal of molecular sciences 2023 Sep 30;24(19)
International journal of molecular sciences 2023 Sep 30;24(19)
Sea Conch Peptides Hydrolysate Alleviates DSS-Induced Colitis in Mice through Immune Modulation and Gut Microbiota Restoration.
Ullah H, Deng T, Ali M, Farooqui NA, Alsholi DM, Siddiqui NZ, Rehman AU, Ali S, Ilyas M, Wang L, Xin Y
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
Molecules (Basel, Switzerland) 2023 Sep 28;28(19)
Long-term PM2.5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models.
Hao S, Chen Z, Gu Y, Chen L, Sheng F, Xu Y, Wu D, Han Y, Lu B, Chen S, Zhao W, Yin H, Wang X, Riazuddin SA, Lou X, Fu Q, Yao K
Particle and fibre toxicology 2023 Sep 27;20(1):36
Particle and fibre toxicology 2023 Sep 27;20(1):36
Multiomics reveal human umbilical cord mesenchymal stem cells improving acute lung injury via the lung-gut axis.
Lv L, Cui EH, Wang B, Li LQ, Hua F, Lu HD, Chen N, Chen WY
World journal of stem cells 2023 Sep 26;15(9):908-930
World journal of stem cells 2023 Sep 26;15(9):908-930
Fasting-mimicking diet alleviates inflammatory pain by inhibiting neutrophil extracellular traps formation and neuroinflammation in the spinal cord.
Li T, Yue Y, Ma Y, Zhong Z, Guo M, Zhang J, Wang Z, Miao C
Cell communication and signaling : CCS 2023 Sep 21;21(1):250
Cell communication and signaling : CCS 2023 Sep 21;21(1):250
Pterostilbene alleviated cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction via inhibiting early endothelial cytoskeleton reorganization and late basement membrane degradation.
Yang ZH, Liu YJ, Ban WK, Liu HB, Lv LJ, Zhang BY, Liu AL, Hou ZY, Lu J, Chen X, You YY
Food & function 2023 Sep 19;14(18):8291-8308
Food & function 2023 Sep 19;14(18):8291-8308
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Wang Y, Zhang J, Zhang B, Lu M, Ma J, Liu Z, Huang J, Ma J, Yang X, Wang F, Tang X
Journal of ethnopharmacology 2023 Sep 15;313:116538
Journal of ethnopharmacology 2023 Sep 15;313:116538
Effects of DON on Mitochondrial Function, Endoplasmic Reticulum Stress, and Endoplasmic Reticulum Mitochondria Contact Sites in the Jejunum of Piglets.
Li X, Gou F, Xiao K, Zhu J, Lin Q, Yu M, Hong Q, Hu C
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13234-13243
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13234-13243
Catalysis-Mediated Male Contraception through Black Phosphorus Nanosheets.
Yi L, Zhu S, Wu P, Zhang Y, Wang M, Xu P, Zeng J, Wang G, Luo L, Li W
ACS applied materials & interfaces 2023 Sep 13;15(36):42284-42292
ACS applied materials & interfaces 2023 Sep 13;15(36):42284-42292
Cerebrospinal Fluid Pressure Reduction Induces Glia-Mediated Retinal Inflammation and Leads to Retinal Ganglion Cell Injury in Rats.
Cheng Y, Lin D, Wu S, Liu Q, Yan X, Ren T, Zhang J, Wang N
Molecular neurobiology 2023 Oct;60(10):5770-5788
Molecular neurobiology 2023 Oct;60(10):5770-5788
The therapeutic value of adipose-derived pericyte transplantation after intracerebral hemorrhage in rats.
Zhang X, Zhou Y, Liu Q, Wang F, Fu L, Wei Y, Ye Y, Guo Y
Journal of molecular histology 2023 Oct;54(5):499-508
Journal of molecular histology 2023 Oct;54(5):499-508
Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans.
Zong X, Zhang H, Zhu L, Deehan EC, Fu J, Wang Y, Jin M
Journal of advanced research 2023 Oct;52:203-218
Journal of advanced research 2023 Oct;52:203-218
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Bian Y, Yin G, Wang G, Liu T, Liang L, Yang X, Zhang W, Tang D
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Lactiplantibacillus plantarum Strain FLPL05 Promotes Longevity in Mice by Improving Intestinal Barrier.
Yu X, Wei M, Yang D, Wu X, Wei H, Xu F
Probiotics and antimicrobial proteins 2023 Oct;15(5):1193-1205
Probiotics and antimicrobial proteins 2023 Oct;15(5):1193-1205
3D Bioprinting of Neurovascular Tissue Modeling with Collagen-Based Low-Viscosity Composites.
Wang S, Bai L, Hu X, Yao S, Hao Z, Zhou J, Li X, Lu H, He J, Wang L, Li D
Advanced healthcare materials 2023 Oct;12(25):e2300004
Advanced healthcare materials 2023 Oct;12(25):e2300004
Chlorogenic Acid Ameliorates Post-Infectious Irritable Bowel Syndrome by Regulating Extracellular Vesicles of Gut Microbes.
Zheng C, Zhong Y, Zhang W, Wang Z, Xiao H, Zhang W, Xie J, Peng X, Luo J, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2302798
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2302798
Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease.
Haferkamp U, Hartmann C, Abid CL, Brachner A, Höchner A, Gerhartl A, Harwardt B, Leckzik S, Leu J, Metzger M, Nastainczyk-Wulf M, Neuhaus W, Oerter S, Pless O, Rujescu D, Jung M, Appelt-Menzel A
Fluids and barriers of the CNS 2023 Oct 31;20(1):78
Fluids and barriers of the CNS 2023 Oct 31;20(1):78
Glucosamine Improves Non-Alcoholic Fatty Liver Disease Induced by High-Fat and High-Sugar Diet through Regulating Intestinal Barrier Function, Liver Inflammation, and Lipid Metabolism.
Li F, Zhang Z, Bai Y, Che Q, Cao H, Guo J, Su Z
Molecules (Basel, Switzerland) 2023 Oct 3;28(19)
Molecules (Basel, Switzerland) 2023 Oct 3;28(19)
Dietary Betaine Supplementation Enhances Colonic Barrier Function through the Nrf2/Keap1 and TLR4-NF-κB/MAPK Signaling Pathways and Alters Colonic Microbiota in Bama Mini-Pigs.
Xiong L, Wang K, Song M, Azad MAK, Zhu Q, Kong X
Antioxidants (Basel, Switzerland) 2023 Oct 29;12(11)
Antioxidants (Basel, Switzerland) 2023 Oct 29;12(11)
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway.
Li H, Zhang C, Zhou Y, Deng Y, Zheng X, Xue X
Aging 2023 Oct 26;15(20):11639-11653
Aging 2023 Oct 26;15(20):11639-11653
Atractylodes lancea Rhizome Polysaccharide Alleviates Immunosuppression and Intestinal Mucosal Injury in Mice Treated with Cyclophosphamide.
Wang D, Dong Y, Xie Y, Xiao Y, Ke C, Shi K, Zhou Z, Tu J, Qu L, Liu Y
Journal of agricultural and food chemistry 2023 Oct 20;
Journal of agricultural and food chemistry 2023 Oct 20;
FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.
Guan X, Wei D, Liang Z, Xie L, Wang Y, Huang Z, Wu J, Pang T
ACS chemical neuroscience 2023 Oct 18;14(20):3839-3854
ACS chemical neuroscience 2023 Oct 18;14(20):3839-3854
Effect of Cordyceps militaris Powder Prophylactic Supplementation on Intestinal Mucosal Barrier Impairment and Microbiota-Metabolites Axis in DSS-Injured Mice.
Wu S, Wu Z, Chen Y
Nutrients 2023 Oct 16;15(20)
Nutrients 2023 Oct 16;15(20)
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis.
Chen F, Wang S, Zeng C, Tang S, Gu H, Wang Z, Li J, Feng P, Zhang Y, Wang P, Wu Y, Shen H
Cellular and molecular life sciences : CMLS 2023 Oct 13;80(11):325
Cellular and molecular life sciences : CMLS 2023 Oct 13;80(11):325
Attenuation of Chronic Stress-Induced Depressive-like Symptoms by Fish Oil via Alleviating Neuroinflammation and Impaired Tryptophan Metabolism in Aging Rats.
Tung TH, Lai WD, Lee HC, Su KP, Panunggal B, Huang SY
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Journal of agricultural and food chemistry 2023 Oct 11;71(40):14550-14561
Effects of Enteromorpha prolifera polysaccharides on growth performance, intestinal barrier function and cecal microbiota in yellow-feathered broilers under heat stress.
Liu W, Liu H, Wang Y, Zhao Z, Balasubramanian B, Jha R
Journal of animal science and biotechnology 2023 Oct 10;14(1):132
Journal of animal science and biotechnology 2023 Oct 10;14(1):132
miR-379-5P INHIBITION ENHANCES INTESTINAL EPITHELIAL PROLIFERATION AND BARRIER FUNCTION RECOVERY AFTER ISCHEMIA/REPERFUSION BY TARGETING EIF4G2.
Jia Z, Wang Y, Gao J, Zheng M, Wang P, Zu G
Shock (Augusta, Ga.) 2023 Oct 1;60(4):594-602
Shock (Augusta, Ga.) 2023 Oct 1;60(4):594-602
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
The coexistence of aflatoxin M1 and ochratoxin A induced intestinal barrier disruption via the regulation of key differentially expressed microRNAs and long non-coding RNAs in BALB/c mice.
Gao YN, Min L, Yang X, Wang JQ, Zheng N
Ecotoxicology and environmental safety 2023 Oct 1;264:115428
Ecotoxicology and environmental safety 2023 Oct 1;264:115428
Nickel induces blood-testis barrier damage through ROS-mediated p38 MAPK pathways in mice.
Zeng Y, Yang Q, Ouyang Y, Lou Y, Cui H, Deng H, Zhu Y, Geng Y, Ouyang P, Chen L, Zuo Z, Fang J, Guo H
Redox biology 2023 Nov;67:102886
Redox biology 2023 Nov;67:102886
Lidocaine ameliorates intestinal barrier dysfunction in irritable bowel syndrome by modulating corticotropin-releasing hormone receptor 2.
Wang Y, Qiao M, Yao X, Feng Z, Hu R, Chen J, Liu L, Liu J, Sun Y, Guo Y
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Neurogastroenterology and motility 2023 Nov;35(11):e14677
Dendrobium huoshanense Polysaccharide Improves High-Fat Diet Induced Liver Injury by Regulating the Gut-Liver Axis.
Ma MH, Gao LL, Chen CB, Gu FL, Wu SQ, Li F, Han BX
Chemistry & biodiversity 2023 Nov;20(11):e202300980
Chemistry & biodiversity 2023 Nov;20(11):e202300980
Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis.
Chen T, Zhang L, Yao L, Luan J, Zhou X, Cong R, Guo X, Qin C, Song N
Environment international 2023 Nov;181:108292
Environment international 2023 Nov;181:108292
Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury.
Li W, Zhao X, Zhang R, Liu X, Qi Z, Zhang Y, Yang W, Pang Y, Zhao C, Fan B, Ran N, Zhang J, Kong X, Feng S, Yao X
Neural regeneration research 2023 Nov;18(11):2474-2481
Neural regeneration research 2023 Nov;18(11):2474-2481
Refined Qingkailing protects the in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury.
Ren Z, Chen C, Zheng Y, Zhang S, Yan J, Cheng F, Wang X, Wang Q, Li C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115580
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115580
Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice.
Xiang XH, Wei J, Wang XF, Xu Q, Yu CL, He CL, Long T, Guo MS, Chen X, Zhou XG, Wu JM, Qin DL, Wu AG, Tang Y, Lv HB
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115478
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115478
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.
Liu H, Xi Q, Tan S, Qu Y, Meng Q, Zhang Y, Cheng Y, Wu G
International immunopharmacology 2023 Nov;124(Pt B):111001
International immunopharmacology 2023 Nov;124(Pt B):111001
Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway.
Sun X, Liu Z, Zhou L, Ma R, Zhang X, Wang T, Fu F, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155071
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155071
Cingulin regulates hair cell cuticular plate morphology and is required for hearing in human and mouse.
Zhu GJ, Huang Y, Zhang L, Yan K, Qiu C, He Y, Liu Q, Zhu C, Morín M, Moreno-Pelayo MÁ, Zhu MS, Cao X, Zhou H, Qian X, Xu Z, Chen J, Gao X, Wan G
EMBO molecular medicine 2023 Nov 8;15(11):e17611
EMBO molecular medicine 2023 Nov 8;15(11):e17611
Quercetin Attenuates the Combined Effects of Zearalenone and Lipopolysaccharide on IPEC-J2 Cell Injury through Activating the Nrf2 Signaling Pathway.
Wang C, Fu Y, Wang R, Wang Q, Yu H, Zhang J
Toxins 2023 Nov 30;15(12)
Toxins 2023 Nov 30;15(12)
Cadmium promotes colorectal cancer metastasis through EGFR/Akt/mTOR signaling cascade and dynamics.
Sun M, Jiang Z, Gu P, Guo B, Li J, Cheng S, Ba Q, Wang H
The Science of the total environment 2023 Nov 15;899:165699
The Science of the total environment 2023 Nov 15;899:165699
Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.
Wei H, Zhen L, Wang S, Yang L, Zhang S, Zhang Y, Jia P, Wang T, Wang K, Zhang Y, Ma L, Lv J, Zhang P
Journal of neuroinflammation 2023 Nov 15;20(1):264
Journal of neuroinflammation 2023 Nov 15;20(1):264
Environmental cadmium exposure facilitates mammary tumorigenesis via reprogramming gut microbiota-mediated glutamine metabolism in MMTV-Erbb2 mice.
Yue Y, Zhang H, Deng P, Tan M, Chen C, Tang B, Li J, Chen F, Zhao Q, Li L, Hao R, Wang H, Luo Y, Tian L, Xie J, Chen M, Yu Z, Zhou Z, Pi H
The Science of the total environment 2023 Nov 1;897:165348
The Science of the total environment 2023 Nov 1;897:165348
Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling.
Li N, Wang R, Li W, Du Q, Deng Z, Fan Y, Zheng L
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16057-16066
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16057-16066
Phlorizin Mitigates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating Gut Microbiota and Inhibiting Ferroptosis.
Cheng J, Liu D, Huang Y, Chen L, Li Y, Yang Z, Fu S, Hu G
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16043-16056
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16043-16056
Dietary Isoquercetin Ameliorates Bone Loss via Restoration of the Gut Microbiota and Lipopolysaccharide-Triggered Inflammatory Status in Ovariectomy Mice.
Wu M, Chen C, Lei H, Cao Z, Zhang C, Du R, Zhang C, Song Y, Qin M, Zhou J, Lu Y, Wang X, Zhang L
Journal of agricultural and food chemistry 2023 Nov 1;71(43):15981-15990
Journal of agricultural and food chemistry 2023 Nov 1;71(43):15981-15990
Bile Acid Derivatives Effectively Prevented High-Fat Diet-Induced Colonic Barrier Dysfunction.
Ma Y, Shan K, Huang Z, Zhao D, Zhang M, Ke W, Li C
Molecular nutrition & food research 2023 May;67(10):e2200649
Molecular nutrition & food research 2023 May;67(10):e2200649
Comparative study of cigarette smoke, Klebsiella pneumoniae, and their combination on airway epithelial barrier function in mice.
Li K, Mei X, Xu K, Jia L, Zhao P, Tian Y, Li J
Environmental toxicology 2023 May;38(5):1133-1142
Environmental toxicology 2023 May;38(5):1133-1142
Interleukin-1β suppresses rabies virus infection by activating cGAS-STING pathway and compromising the blood-brain barrier integrity in mice.
Wu D, Wang J, Huang C, Zhao J, Fu ZF, Zhao L, Zhou M
Veterinary microbiology 2023 May;280:109708
Veterinary microbiology 2023 May;280:109708
Globoside and the mucosal pH mediate parvovirus B19 entry through the epithelial barrier.
Suter C, Colakovic M, Bieri J, Gultom M, Dijkman R, Ros C
PLoS pathogens 2023 May;19(5):e1011402
PLoS pathogens 2023 May;19(5):e1011402
Oral Metal-Free Melanin Nanozymes for Natural and Durable Targeted Treatment of Inflammatory Bowel Disease (IBD).
Huang Q, Yang Y, Zhu Y, Chen Q, Zhao T, Xiao Z, Wang M, Song X, Jiang Y, Yang Y, Zhang J, Xiao Y, Nan Y, Wu W, Ai K
Small (Weinheim an der Bergstrasse, Germany) 2023 May;19(19):e2207350
Small (Weinheim an der Bergstrasse, Germany) 2023 May;19(19):e2207350
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Ma N, Ma D, Liu X, Zhao L, Ma L, Ma D, Dong S
Environment international 2023 May;175:107949
Environment international 2023 May;175:107949
Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps.
Zhang M, Xiong Y, Tu J, Tang B, Zhang Z, Yu J, Shen L, Luo Q, Ye J
International immunopharmacology 2023 May;118:110054
International immunopharmacology 2023 May;118:110054
Shengjiang Xiexin Decoction ameliorates antibiotic-associated diarrhea by altering the gut microbiota and intestinal metabolic homeostasis.
Zhang CE, Yu XH, Cui YT, Wang HJ, Chen X, Ma XJ, Li H, Su JR, Ma ZJ, Huang LQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154737
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 May;113:154737
The protective effects of electroacupuncture on intestinal barrier lesions in IBS and UC model.
Liu S, Huang Q, Huang Q, Wang Y, Li S, Wang J, Wu Q
Scientific reports 2023 May 4;13(1):7276
Scientific reports 2023 May 4;13(1):7276
HCMV Infection Reduces Nidogen-1 Expression, Contributing to Impaired Neural Rosette Development in Brain Organoids.
Ijezie EC, O'Dowd JM, Kuan MI, Faeth AR, Fortunato EA
Journal of virology 2023 May 31;97(5):e0171822
Journal of virology 2023 May 31;97(5):e0171822
Gut Microbiota from Short-Chain Chlorinated Paraffin-Exposed Mice Promotes Astrocyte Activation by Disrupting the Intestinal Tight Junction via Zonulin Upregulation.
Zhao X, Zhang T, Zheng Y, Zhao Z, Ding W, Zhang Z, Zhang Z, Wang R, Jiao M, Liu L, Yu S, Wang X, Huang R, Wu Q
Journal of agricultural and food chemistry 2023 May 31;71(21):8192-8202
Journal of agricultural and food chemistry 2023 May 31;71(21):8192-8202
Baicalin Attenuates H(2)O(2)-Induced Oxidative Stress by Regulating the AMPK/Nrf2 Signaling Pathway in IPEC-J2 Cells.
Liang J, Zhou Y, Cheng X, Chen J, Cao H, Guo X, Zhang C, Zhuang Y, Hu G
International journal of molecular sciences 2023 May 29;24(11)
International journal of molecular sciences 2023 May 29;24(11)
Calcitriol, an Active Form of Vitamin D3, Mitigates Skin Barrier Dysfunction in Atopic Dermatitis NC/Nga Mice.
Umehara Y, Trujillo-Paez JV, Yue H, Peng G, Nguyen HLT, Okumura K, Ogawa H, Niyonsaba F
International journal of molecular sciences 2023 May 27;24(11)
International journal of molecular sciences 2023 May 27;24(11)
Discovering a Reversible Male Contraceptive Agent Derived from Lonidamine.
Gong S, Zhu S, Zhou P, Cheng CY, Li W, Yao W, Sun F
ACS omega 2023 May 23;8(20):18245-18254
ACS omega 2023 May 23;8(20):18245-18254
Sulfur dioxide derivatives aggravated ovalbumin-induced asthma through targeting TRPV1 and tight junctions.
Zhou L, Lao Z, Fan X, Hao M, Yang Y
Bioscience, biotechnology, and biochemistry 2023 May 19;87(6):627-637
Bioscience, biotechnology, and biochemistry 2023 May 19;87(6):627-637
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zhang MF, Wan SC, Chen WB, Yang DH, Liu WQ, Li BL, Aierken A, Du XM, Li YX, Wu WP, Yang XC, Wei YD, Li N, Peng S, Li XL, Li GP, Hua JL
Zoological research 2023 May 18;44(3):505-521
Zoological research 2023 May 18;44(3):505-521
Therapeutic mechanisms of the medicine and food homology formula Xiao-Ke-Yin on glucolipid metabolic dysfunction revealed by transcriptomics, metabolomics and microbiomics in mice.
Li M, Cheng D, Peng C, Huang Y, Geng J, Huang G, Wang T, Xu A
Chinese medicine 2023 May 18;18(1):57
Chinese medicine 2023 May 18;18(1):57
Hydrogen inhalation ameliorates hepatic inflammation and modulates gut microbiota in rats with high-fat diet-induced non-alcoholic fatty liver disease.
Xue J, Zhao M, Liu Y, Jia X, Zhang X, Gu Q, Xie Y, Qin S, Liu B
European journal of pharmacology 2023 May 15;947:175698
European journal of pharmacology 2023 May 15;947:175698
Bazedoxifene attenuates intestinal injury in sepsis by suppressing the NF-κB/NLRP3 signaling pathways.
Zhang X, Ning W, Gao G, Zhou Y, Duan XB, Li X, Li D, Guo R
European journal of pharmacology 2023 May 15;947:175681
European journal of pharmacology 2023 May 15;947:175681
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Zhao X, He X, Wei W, Huang K
European journal of pharmacology 2023 May 15;947:175671
European journal of pharmacology 2023 May 15;947:175671
HC067047 Ameliorates Sepsis-associated Encephalopathy by Suppressing Endoplasmic Reticulum Stress and Oxidative Stress-Induced Pyroptosis in the Hippocampi of Mice.
Zhong X, Wang Y, Liu D, Liang Y, Liu W, Huang Y, Xie L, Cao W, Xu Y, Chen L
Neuroscience 2023 May 1;517:117-127
Neuroscience 2023 May 1;517:117-127
The role of ferroptosis mediated by Bmal1/Nrf2 in nicotine -induce injury of BTB integrity.
Zhang Z, Cheng J, Yang L, Li X, Hua R, Xu D, Jiang Z, Li Q
Free radical biology & medicine 2023 May 1;200:26-35
Free radical biology & medicine 2023 May 1;200:26-35
Microtubule-associated protein 4 promotes epithelial mesenchymal transition in hepatocellular cancer cells via regulating GSK3β/β-catenin pathway.
Hu P, Zong B, Chen Q, Shao R, Chen M, Yang Y, Shao G
Heliyon 2023 Mar;9(3):e14309
Heliyon 2023 Mar;9(3):e14309
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
Yao F, Luo Y, Chen Y, Li Y, Hu X, You X, Li Z, Yu S, Tian D, Zheng M, Cheng L, Jing J
Cellular and molecular neurobiology 2023 Mar;43(2):741-756
Cellular and molecular neurobiology 2023 Mar;43(2):741-756
Polygonum tinctorium leaf extract ameliorates high-fat diet-induced intestinal epithelial damage in mice.
Kawaguchi S, Sakuraba H, Kikuchi H, Matsuki K, Hayashi Y, Ding J, Tanaka Y, Seya K, Matsumiya T, Hiraga H, Fukuda S, Sasaki K, Imaizumi T
Experimental and therapeutic medicine 2023 Mar;25(3):112
Experimental and therapeutic medicine 2023 Mar;25(3):112
A novel model of subretinal edema induced by DL-alpha aminoadipic acid.
Xie Z, Wu X, Cheng R, Huang J, Wang X, Shi Q, Xu B, Paulus YM, Yuan S, Liu Q
Experimental eye research 2023 Mar;228:109388
Experimental eye research 2023 Mar;228:109388
The Polo-Like Kinase 1-Mammalian Target of Rapamycin Axis Regulates Autophagy to Prevent Intestinal Barrier Dysfunction During Sepsis.
Cao YY, Qiao Y, Wang ZH, Chen Q, Qi YP, Lu ZM, Wang Z, Lu WH
The American journal of pathology 2023 Mar;193(3):296-312
The American journal of pathology 2023 Mar;193(3):296-312
S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung.
Hao M, Fu R, Tai J, Tian Z, Yuan X, Chen Y, Wang M, Jiang H, Ji M, Lai F, Xue N, Bai L, Zhu Y, Lv X, Chen X, Jin J
Acta pharmaceutica Sinica. B 2023 Mar;13(3):1110-1127
Acta pharmaceutica Sinica. B 2023 Mar;13(3):1110-1127
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia.
Wang P, Li T, Niu C, Sun S, Liu D
International immunopharmacology 2023 Mar;116:109763
International immunopharmacology 2023 Mar;116:109763
Calcitonin gene-related peptide ameliorates sepsis-induced intestinal injury by suppressing NLRP3 inflammasome activation.
Ning W, Gao G, Zhou Y, Li WQ, Yang HH, Duan XB, Li X, Gong YB, Li D, Guo R
International immunopharmacology 2023 Mar;116:109747
International immunopharmacology 2023 Mar;116:109747
HC067047 as a potent TRPV4 inhibitor repairs endotoxemia colonic injury.
Chen L, Mao M, Liu D, Liu W, Wang Y, Xie L, Deng Y, Lin Y, Xu Y, Zhong X, Cao W
International immunopharmacology 2023 Mar;116:109648
International immunopharmacology 2023 Mar;116:109648
Cimifugin suppresses type 2 airway inflammation by binding to SPR and regulating its protein expression in a non-enzymatic manner.
Gu X, Chen Y, Qian P, He T, Wu Y, Lin W, Zheng J, Hong M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154657
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154657
Long-term Pu-erh tea consumption improves blue light-induced depression-like behaviors.
Zhao S, Hu S, Sun K, Luo L, Zeng L
Food & function 2023 Mar 6;14(5):2313-2325
Food & function 2023 Mar 6;14(5):2313-2325
Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis.
Zhang ML, Wang M, Chen J, Liu YJ, Yu YJ, Liu LM, Zheng XH, Xiao YC, Zhang JM, Zhu MX, Yue X, Zhao Y, Niu W, Li ZC
European journal of pharmacology 2023 Mar 5;942:175545
European journal of pharmacology 2023 Mar 5;942:175545
p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands.
Gao J, Li A, Fujii S, Huang F, Nakatomi C, Nakamura I, Honda H, Kiyoshima T, Jimi E
Scientific reports 2023 Mar 29;13(1):5144
Scientific reports 2023 Mar 29;13(1):5144
Integration of metabolomics and transcriptomics to reveal ferroptosis is involved in Tripterygium wilfordii polyglycoside tablet-induced testicular injury.
Qin Z, Zhang G, Jiang S, Ning F, Zhao Z, Huang M, Jin J
Journal of ethnopharmacology 2023 Mar 25;304:116055
Journal of ethnopharmacology 2023 Mar 25;304:116055
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice.
Wei R, Su Z, Mackenzie GG
Food & function 2023 Mar 20;14(6):2684-2697
Food & function 2023 Mar 20;14(6):2684-2697
Alteration of gut microbiome and metabolome by Clostridium butyricum can repair the intestinal dysbiosis caused by antibiotics in mice.
Liu X, Qiu X, Yang Y, Wang J, Wang Q, Liu J, Yang F, Liu Z, Qi R
iScience 2023 Mar 17;26(3):106190
iScience 2023 Mar 17;26(3):106190
Emblica officinalis mitigates intestinal toxicity of mice by modulating gut microbiota in lead exposure.
Wang Y, Zhou H, Che Y, Wan X, Ding X, Zheng S, Wu C, Qin M, Xu Y, Yu Y, Kulyar MF, Li K, Wu Y
Ecotoxicology and environmental safety 2023 Mar 15;253:114648
Ecotoxicology and environmental safety 2023 Mar 15;253:114648
Highly stable fibronectin-mimetic-peptide-based supramolecular hydrogel to accelerate corneal wound healing.
Hu Y, Shi H, Ma X, Xia T, Wu Y, Chen L, Ren Z, Lei L, Jiang J, Wang J, Li X
Acta biomaterialia 2023 Mar 15;159:128-139
Acta biomaterialia 2023 Mar 15;159:128-139
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
Lin L, Yang J, Zhang D, Lv Q, Wang F, Liu P, Wang M, Shi C, Huang X, Liang W, Tan C, Wang X, Chen H, Wilson BA, Wu B, Peng Z
Microbiology spectrum 2023 Mar 14;11(2):e0455422
Microbiology spectrum 2023 Mar 14;11(2):e0455422
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression.
Yang F, Li L, Zhou Y, Pan W, Liang X, Huang L, Huang J, Cheng Y, Geng L, Xu W, Gong S
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):516-526
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):516-526
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Wang Y, Zhang L, Lv L, Zhou Z, Xi H
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Tongqiao Huoxue Decoction ameliorates traumatic brain injury-induced gastrointestinal dysfunction by regulating CD36/15-LO/NR4A1 signaling, which fails when CD36 and CX3CR1 are deficient.
Wei C, Zhu F, Yu J, Gao F, Yuan Y, Zhang Y, Liu X, Chu S, Cui D, Fan H, Wang W
CNS neuroscience & therapeutics 2023 Jun;29 Suppl 1(Suppl 1):161-184
CNS neuroscience & therapeutics 2023 Jun;29 Suppl 1(Suppl 1):161-184
SRT1720 attenuates UVA-induced corneal endothelial damage via inhibition of oxidative stress and cellular apoptosis.
Dong C, Li Z, Wang X, Zou D, Duan H, Zhao C, Zhou Q, Shi W
Experimental eye research 2023 Jun;231:109464
Experimental eye research 2023 Jun;231:109464
Dopamine D1 receptor agonist alleviates acute lung injury via modulating inflammatory responses in macrophages and barrier function in airway epithelial cells.
Meng L, Wang M, Gao Y, Chen L, Wang K, Gao W, Liu Q
Free radical biology & medicine 2023 Jun;202:2-16
Free radical biology & medicine 2023 Jun;202:2-16
Spermidine protects intestinal mucosal barrier function in mice colitis via the AhR/Nrf2 and AhR/STAT3 signaling pathways.
Yan B, Mao X, Hu S, Wang S, Liu X, Sun J
International immunopharmacology 2023 Jun;119:110166
International immunopharmacology 2023 Jun;119:110166
YES-associated protein-regulated Smad7 worsen epithelial barrier injury of chronic sinusitis with nasal polyps.
Jiang X, Shu L, Liu Y, Shen Y, Ke X, Liu J, Yang Y
Immunity, inflammation and disease 2023 Jun;11(6):e907
Immunity, inflammation and disease 2023 Jun;11(6):e907
Systematic assessment of hexavalent chromium-induced damage to male fertility and the preventive role of melatonin: a longitudinal study from the translational point of view.
Li T, Lv Y, Wu Z, Guo M, Liu R, Zeng W, Zheng Y
Molecular human reproduction 2023 Jun 30;29(7)
Molecular human reproduction 2023 Jun 30;29(7)
Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice.
Liu C, Zhou Y, Gao H, Zhang Z, Zhou Y, Xu Z, Zhang C, Xu Z, Zheng H, Ma YQ
Thrombosis journal 2023 Jun 29;21(1):71
Thrombosis journal 2023 Jun 29;21(1):71
Non-Invasive and Label-Free On-Chip Impedance Monitoring of Heatstroke.
Zhao Y, Fan W, Liu A, Pan S, Xu C, Peng H, Yin B, Wang X, Dong J, Pan Z
Biosensors 2023 Jun 27;13(7)
Biosensors 2023 Jun 27;13(7)
Fecal microbiota transplantation from sodium alginate-dosed mice and normal mice mitigates intestinal barrier injury and gut dysbiosis induced by antibiotics and cyclophosphamide.
Huang J, Zhou H, Song T, Wang B, Ge H, Zhang D, Shen P, Qiu X, Li H
Food & function 2023 Jun 19;14(12):5690-5701
Food & function 2023 Jun 19;14(12):5690-5701
Supplementing a specific synbiotic suppressed the incidence of AOM/DSS-induced colorectal cancer in mice.
Wu H, Wu Z, Qiu Y, Zhao F, Liao M, Zhong Z, Chen J, Zeng Y, Liu R
iScience 2023 Jun 16;26(6):106979
iScience 2023 Jun 16;26(6):106979
Kinsenoside alleviates oxidative stress-induced blood-brain barrier dysfunction via promoting Nrf2/HO-1 pathway in ischemic stroke.
Qiao N, An Z, Fu Z, Chen X, Tong Q, Zhang Y, Ren H
European journal of pharmacology 2023 Jun 15;949:175717
European journal of pharmacology 2023 Jun 15;949:175717
Diosmetin Maintains Barrier Integrity by Reducing the Expression of ABCG2 in Colonic Epithelial Cells.
Liu J, Fu L, Yin F, Yin L, Song X, Guo H, Liu J
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
Journal of agricultural and food chemistry 2023 Jun 14;71(23):8931-8940
Polystyrene microplastics aggravate acute pancreatitis in mice.
Zheng J, Tan Z, Wu J, Liu J, Yang T, Yang H
Toxicology 2023 Jun 1;491:153513
Toxicology 2023 Jun 1;491:153513
MiR-26a-5p from HucMSC-derived extracellular vesicles inhibits epithelial mesenchymal transition by targeting Adam17 in silica-induced lung fibrosis.
Zhao J, Jiang Q, Xu C, Jia Q, Wang H, Xue W, Wang Y, Zhu Z, Tian L
Ecotoxicology and environmental safety 2023 Jun 1;257:114950
Ecotoxicology and environmental safety 2023 Jun 1;257:114950
Fluoride disrupts intestinal epithelial tight junction integrity through intracellular calcium-mediated RhoA/ROCK signaling and myosin light chain kinase.
Li L, Xin J, Wang H, Wang Y, Peng W, Sun N, Huang H, Zhou Y, Liu X, Lin Y, Fang J, Jing B, Pan K, Zeng Y, Zeng D, Qin X, Bai Y, Ni X
Ecotoxicology and environmental safety 2023 Jun 1;257:114940
Ecotoxicology and environmental safety 2023 Jun 1;257:114940
Arsenic interferes with spermatogenesis involving Rictor/mTORC2-mediated blood-testis barrier disruption in mice.
Li X, Wang W, Hou Y, Li G, Yi H, Cui S, Zhang J, He X, Zhao H, Yang Z, Qiu Y, Liu Z, Xie J
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Ecotoxicology and environmental safety 2023 Jun 1;257:114914
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Huang Y, Liu J, He J, Tan F, Lu M, Yuan F, Zhu X, Kong L
Heliyon 2023 Jul;9(7):e17874
Heliyon 2023 Jul;9(7):e17874
Effect of lonidamine derivatives on the inhibition of transformed cell area expansion.
Aoyama M, Homma T, Koharazawa R, Suhara Y, Semba K
Biochemistry and biophysics reports 2023 Jul;34:101480
Biochemistry and biophysics reports 2023 Jul;34:101480
Thioredoxin1 is a target to attenuate diabetes‑induced RPE cell dysfunction in human ARPE19 cells by alleviating oxidative stress.
Qi H, Liu T, Liu J, Teng Q, Ma Z, Wang S, Wen S, Zhang C, Ren X, Kong H, Kong L
Molecular medicine reports 2023 Jul;28(1)
Molecular medicine reports 2023 Jul;28(1)
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Matrix metalloproteinases are key targets of acupuncture in the treatment of ulcerative colitis.
Zhang RB, Dong LC, Huang Q, Shen Y, Li HY, Yu SG, Wu QF
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1229-1241
Protective effects of melatonin on deoxynivalenol-induced oxidative stress and autophagy in IPEC-J2 cells.
Xu Y, Xie Y, Wu Z, Wang H, Chen Z, Wang J, Bao W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113803
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113803
Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases.
Guo HH, Shen HR, Wang LL, Luo ZG, Zhang JL, Zhang HJ, Gao TL, Han YX, Jiang JD
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114754
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114754
The ACE2 activator diminazene aceturate ameliorates colitis by repairing the gut-vascular barrier in mice.
Zhang C, Cao X, Wang H, Li Z, Zhang Y
Microvascular research 2023 Jul;148:104544
Microvascular research 2023 Jul;148:104544
Programmed cell death 10 increased blood-brain barrier permeability through HMGB1/TLR4 mediated downregulation of endothelial ZO-1 in glioblastoma.
Wu S, Wang J, Liu J, Zhu H, Li R, Wan X, Lei J, Li Y, You C, Hu F, Zhang S, Zhao K, Shu K, Lei T
Cellular signalling 2023 Jul;107:110683
Cellular signalling 2023 Jul;107:110683
Effects of the polypeptide from peanut meal mixed fermentation on lipid metabolism and intestinal flora of hyperlipidemic mice.
Ding H, Zhang H, Lu Y, Jiang X, Liu Q, Hu Y, Sun H, Ma A
Journal of the science of food and agriculture 2023 Jul;103(9):4351-4359
Journal of the science of food and agriculture 2023 Jul;103(9):4351-4359
DSPE-PEG polymer enhanced berberine absorption specifically in the small intestine of rats through paracellular passway.
Gao Y, Sun J, Wang S, Huxiao L, Xu Y, Zhang H
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):931-939
The Journal of pharmacy and pharmacology 2023 Jul 5;75(7):931-939
The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage.
Ghosh S, Erickson D, Chua MJ, Collins J, Jala VR
bioRxiv : the preprint server for biology 2023 Jul 24;
bioRxiv : the preprint server for biology 2023 Jul 24;
Mn(3)O(4) Nanozyme Loaded Thermosensitive PDLLA-PEG-PDLLA Hydrogels for the Treatment of Inflammatory Bowel Disease.
Yang Z, Zhou X, Wang L, Guo H, Han M, Guo H, Chen Y, Wu A, Li H, Chen S, Xie Y, Wang X
ACS applied materials & interfaces 2023 Jul 19;15(28):33273-33287
ACS applied materials & interfaces 2023 Jul 19;15(28):33273-33287
Alginate oligosaccharide structures differentially affect DSS-induced colitis in mice by modulating gut microbiota.
Lu S, Na K, Wei J, Tao T, Zhang L, Fang Y, Li X, Guo X
Carbohydrate polymers 2023 Jul 15;312:120806
Carbohydrate polymers 2023 Jul 15;312:120806
Open source board based acoustofluidic transwells for reversible disruption of the blood-brain barrier for therapeutic delivery.
Wang K, Sun C, Dumčius P, Zhang H, Liao H, Wu Z, Tian L, Peng W, Fu Y, Wei J, Cai M, Zhong Y, Li X, Yang X, Cui M
Biomaterials research 2023 Jul 15;27(1):69
Biomaterials research 2023 Jul 15;27(1):69
Mechanistic study for drug induced cholestasis using batch-fabricated 3D spheroids developed by agarose-stamping method.
Guo H, Yu H, Zu H, Cui J, Ding H, Xia Y, Chen D, Zeng Y, Wang Y, Wang Y, Zhang LW
Toxicology letters 2023 Jul 1;383:64-74
Toxicology letters 2023 Jul 1;383:64-74
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Chen W, Yu H, Sun C, Dong M, Zhao N, Wang Y, Yu K, Zhang J, Xu N, Liu W
Toxicology letters 2023 Jul 1;383:177-191
Toxicology letters 2023 Jul 1;383:177-191
Hexavalent chromium disrupts the skin barrier by targeting ROS-mediated mitochondrial pathway apoptosis in keratinocytes.
Wang C, Shang H, Zhang S, Wang X, Liu D, Shen M, Li N, Jiang Y, Wei K, Zhu R
Chemico-biological interactions 2023 Jul 1;379:110523
Chemico-biological interactions 2023 Jul 1;379:110523
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis.
Wang CQ, Su Z, Dai CG, Song JL, Qian B
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Ecotoxicology and environmental safety 2023 Jul 1;259:115041
Therapeutic potential of nanoceria pretreatment in preventing the development of urological chronic pelvic pain syndrome: Immunomodulation via reactive oxygen species scavenging and SerpinB2 downregulation.
Lien WC, Zhou XR, Liang YJ, Ching CT, Wang CY, Lu FI, Chang HC, Lin FH, Wang HD
Bioengineering & translational medicine 2023 Jan;8(1):e10346
Bioengineering & translational medicine 2023 Jan;8(1):e10346
Perlecan Improves Blood Spinal Cord Barrier Repair Through the Integrin β1/ROCK/MLC Pathway After Spinal Cord Injury.
Xie C, Wang Y, Wang J, Xu Y, Liu H, Guo J, Zhu L
Molecular neurobiology 2023 Jan;60(1):51-67
Molecular neurobiology 2023 Jan;60(1):51-67
Apelin-13 prevents the effects of oxygen-glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT-mTOR signaling.
Zhang R, Wu F, Cheng B, Wang C, Bai B, Chen J
Experimental biology and medicine (Maywood, N.J.) 2023 Jan;248(2):146-156
Experimental biology and medicine (Maywood, N.J.) 2023 Jan;248(2):146-156
Metasilicate-based alkaline mineral water confers diarrhea resistance in maternally separated piglets via the microbiota-gut interaction.
Chen J, Xu XW, Kang JX, Zhao BC, Xu YR, Li JL
Pharmacological research 2023 Jan;187:106580
Pharmacological research 2023 Jan;187:106580
Desulfovibrio desulfuricans aggravates atherosclerosis by enhancing intestinal permeability and endothelial TLR4/NF-κB pathway in Apoe (-/-) mice.
Zhang K, Qin X, Qiu J, Sun T, Qu K, Din AU, Yan W, Li T, Chen Y, Gu W, Rao X, Wang G
Genes & diseases 2023 Jan;10(1):239-253
Genes & diseases 2023 Jan;10(1):239-253
A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection.
Däullary T, Imdahl F, Dietrich O, Hepp L, Krammer T, Fey C, Neuhaus W, Metzger M, Vogel J, Westermann AJ, Saliba AE, Zdzieblo D
Gut microbes 2023 Jan-Dec;15(1):2186109
Gut microbes 2023 Jan-Dec;15(1):2186109
FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
Li B, Xi W, Bai Y, Liu X, Zhang Y, Li L, Bian L, Liu C, Tang Y, Shen L, Yang L, Gu X, Xie J, Zhou Z, Wang Y, Yu X, Wang J, Chao J, Han B, Yao H
Nature communications 2023 Jan 30;14(1):489
Nature communications 2023 Jan 30;14(1):489
Effects of 6-Shogaol on Glucose Uptake and Intestinal Barrier Integrity in Caco-2 Cells.
Jiao W, Sang Y, Wang X, Wang S
Foods (Basel, Switzerland) 2023 Jan 21;12(3)
Foods (Basel, Switzerland) 2023 Jan 21;12(3)
Gut Bacterial Indole-3-acetic Acid Induced Immune Promotion Mediates Preventive Effects of Fu Brick Tea Polyphenols on Experimental Colitis.
Zhang X, Shi L, Wang N, Li Q, Zhang L, Han N, Yan T, Ren D, Zhang B, Zhao Y, Yang X
Journal of agricultural and food chemistry 2023 Jan 18;71(2):1201-1213
Journal of agricultural and food chemistry 2023 Jan 18;71(2):1201-1213
Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions.
Adzraku SY, Wang G, Cao C, Bao Y, Wang Y, Smith AO, Du Y, Wang H, Li Y, Xu K, Qiao J, Ju W, Zeng L
Cellular & molecular biology letters 2023 Jan 16;28(1):2
Cellular & molecular biology letters 2023 Jan 16;28(1):2
Intestinal epithelium penetration of liraglutide via cholic acid pre-complexation and zein/rhamnolipids nanocomposite delivery.
Bao X, Qian K, Xu M, Chen Y, Wang H, Pan T, Wang Z, Yao P, Lin L
Journal of nanobiotechnology 2023 Jan 16;21(1):16
Journal of nanobiotechnology 2023 Jan 16;21(1):16
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
Yang Z, Wang YX, Wen JK, Gao HT, Han ZW, Qi JC, Gu JF, Zhao CM, Zhang H, Shi B, Wang DD, Wang XL, Qu CB
Cell death & disease 2023 Jan 13;14(1):26
Cell death & disease 2023 Jan 13;14(1):26
β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota.
Zhang X, Zhang Y, He Y, Zhu X, Ai Q, Shi Y
Journal of translational medicine 2023 Jan 10;21(1):14
Journal of translational medicine 2023 Jan 10;21(1):14
Involvement of gut-brain communication in arsenite-induced neurobehavioral impairments in adult male mice.
Lu Z, Wang F, Xia Y, Cheng S, Zhang J, Qin X, Tian X, Wang B, Qiu J, Zou Z, Jiang X, Chen C
Ecotoxicology and environmental safety 2023 Jan 1;249:114370
Ecotoxicology and environmental safety 2023 Jan 1;249:114370
ADP-ribose transferase PARP16 mediated-unfolded protein response contributes to neuronal cell damage in cerebral ischemia/reperfusion.
Wang J, Xu J, Dong Y, Su Z, Su H, Cheng Q, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22788
Effects of Buyang Huanwu Decoction on Intestinal Barrier, Intestinal Flora, and Trimethylamine Oxide in Rats with Heart Failure.
Weng JQ, Li JB, Yuan MF, Yao TT, Zhang JF, Zeng YY, Zhao J, Li Y, Xu K, Shen XX
Chinese journal of integrative medicine 2023 Feb;29(2):155-161
Chinese journal of integrative medicine 2023 Feb;29(2):155-161
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Li B, Li W, Zheng M, Wang Y, Diao Y, Mou X, Liu J
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
Experimental biology and medicine (Maywood, N.J.) 2023 Feb;248(4):317-326
Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses.
Scheibner D, Salaheldin AH, Bagato O, Zaeck LM, Mostafa A, Blohm U, Müller C, Eweas AF, Franzke K, Karger A, Schäfer A, Gischke M, Hoffmann D, Lerolle S, Li X, Abd El-Hamid HS, Veits J, Breithaupt A, Boons GJ, Matrosovich M, Finke S, Pleschka S, Mettenleiter TC, de Vries RP, Abdelwhab EM
PLoS pathogens 2023 Feb;19(2):e1011135
PLoS pathogens 2023 Feb;19(2):e1011135
Capsaicin shapes gut microbiota and pre-metastatic niche to facilitate cancer metastasis to liver.
Cheng P, Wu J, Zong G, Wang F, Deng R, Tao R, Qian C, Shan Y, Wang A, Zhao Y, Wei Z, Lu Y
Pharmacological research 2023 Feb;188:106643
Pharmacological research 2023 Feb;188:106643
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
Wu F, Wang P, Wei X, Yang Y, Al Mamun A, Zhang X, Zhu Y, Mo T, Zhang H, Jiang C, Hu J, Xiao J
Materials today. Bio 2023 Feb;18:100546
Materials today. Bio 2023 Feb;18:100546
PLK1 protects intestinal barrier function in sepsis: A translational research.
Cao YY, Li J, Chen Q, Qi YP, Xu QC, He JM, Wang Z, Lu WH
Cytokine 2023 Feb;162:156113
Cytokine 2023 Feb;162:156113
DHA-enriched phosphatidylserine alleviates high fat diet-induced jejunum injury in mice by modulating gut microbiota.
Tian S, Zhao Y, Qian L, Jiang S, Tang Y, Han T
Food & function 2023 Feb 6;14(3):1415-1429
Food & function 2023 Feb 6;14(3):1415-1429
Lutein Prevents Liver Injury and Intestinal Barrier Dysfunction in Rats Subjected to Chronic Alcohol Intake.
Zhao S, Zhang Y, Ding H, Hu S, Wu X, Ma A, Ma Y
Nutrients 2023 Feb 28;15(5)
Nutrients 2023 Feb 28;15(5)
Fecal microbiota transplantation attenuates Escherichia coli infected outgrowth by modulating the intestinal microbiome.
Wang Y, He Y, Liang Y, Liu H, Chen X, Kulyar MF, Shahzad A, Wei K, Li K
Microbial cell factories 2023 Feb 17;22(1):30
Microbial cell factories 2023 Feb 17;22(1):30
Small molecule compound K-7174 attenuates neuropsychiatric manifestations in lupus-prone mice.
Fan Y, Liu X, Wu J, Ni J, Liang J, Hou Y, Dou H
Brain research 2023 Feb 15;1801:148203
Brain research 2023 Feb 15;1801:148203
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Guo TT, Zhang Z, Sun Y, Zhu RY, Wang FX, Ma LJ, Jiang L, Liu HD
Nutrients 2023 Feb 13;15(4)
Nutrients 2023 Feb 13;15(4)
Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice.
Wang X, Huang S, Zhang M, Su Y, Pan Z, Liang J, Xie X, Wang Q, Chen J, Zhou L, Luo X
Journal of ethnopharmacology 2023 Feb 10;302(Pt B):115919
Journal of ethnopharmacology 2023 Feb 10;302(Pt B):115919
Effects of Houpo Mahuang Decoction on serum metabolism and TRPV1/Ca(2+)/TJs in asthma.
Zhou L, Hao M, Fan X, Lao Z, Li M, Shang E
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115873
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115873
Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE-19 Cells.
Ren C, Zhou P, Zhang M, Yu Z, Zhang X, Tombran-Tink J, Barnstable CJ, Li X
International journal of molecular sciences 2023 Feb 10;24(4)
International journal of molecular sciences 2023 Feb 10;24(4)
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
Lin D, Sun Q, Liu Z, Pan J, Zhu J, Wang S, Jia S, Zheng M, Li X, Gong F
Free radical biology & medicine 2023 Feb 1;195:199-218
Free radical biology & medicine 2023 Feb 1;195:199-218
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1.
Gao J, Wang Y, Jia Z, Xue J, Zhou T, Zu G
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Pharmaceutical biology 2023 Dec;61(1):1310-1317
Toxicity assessment of organophosphate flame retardant triphenyl phosphate (TPHP) on intestines in mice.
Peng C, Zhang X, Chen Y, Wang L
Ecotoxicology and environmental safety 2023 Dec;268:115685
Ecotoxicology and environmental safety 2023 Dec;268:115685
Increased R-spondin 3 contributes to aerobic exercise-induced protection against renal vascular endothelial hyperpermeability and acute kidney injury.
Xu QF, Zhang H, Zhao Y, Liu D, Wei J, Jiang L, Liu YJ, Zhu XY
Acta physiologica (Oxford, England) 2023 Dec;239(4):e14036
Acta physiologica (Oxford, England) 2023 Dec;239(4):e14036
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Li J, Bai J, Song Z, Ji Y, Chen Z, Yang Y, Wu Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
Wen W, Xu Y, Qian W, Huang L, Gong J, Li Y, Zhu W, Guo Z
Gut microbes 2023 Dec;15(2):2265578
Gut microbes 2023 Dec;15(2):2265578
The E3 ubiquitin ligase RNF31 mediates the development of ulcerative colitis by regulating NLRP3 inflammasome activation.
Wang P, Tang CT, Li J, Huang X, Jin R, Yin F, Liu Z, Chen Y, Zeng C
International immunopharmacology 2023 Dec;125(Pt B):111194
International immunopharmacology 2023 Dec;125(Pt B):111194
Ursodeoxycholic acid alleviates sepsis-induced lung injury by blocking PANoptosis via STING pathway.
He YQ, Deng JL, Zhou CC, Jiang SG, Zhang F, Tao X, Chen WS
International immunopharmacology 2023 Dec;125(Pt B):111161
International immunopharmacology 2023 Dec;125(Pt B):111161
Combined VEGF and bFGF loaded nanofiber membrane protects against neuronal injury and hypomyelination in a rat model of chronic cerebral hypoperfusion.
Wu YF, Sun J, Chen M, Lin Q, Jin KY, Su SH, Hai J
International immunopharmacology 2023 Dec;125(Pt A):111108
International immunopharmacology 2023 Dec;125(Pt A):111108
Protective effect of ethyl ferulate against hypoxic injury in retinal cells and retinal neovascularization in an oxygen-induced retinopathy model.
Xue R, Fan XL, Yang Q, Yu C, Lu TY, Wan GM
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155097
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155097
Dual-Targeted Nanoparticle-in-Microparticle System for Ulcerative Colitis Therapy.
Zhang Y, Wu Y, Yan Y, Ma Y, Tu L, Shao J, Tang X, Chen L, Liang G, Yin L
Advanced healthcare materials 2023 Dec;12(31):e2301518
Advanced healthcare materials 2023 Dec;12(31):e2301518
Effects of enteral nutrition supplemented with octanoic acid on lipopolysaccharide-induced intestinal injury: role of peroxisome proliferator-activated receptor γ/STAT-1/myeloid differentiation factor 88 pathway.
Tang J, Li X, Li W, Cao C
Nutrition (Burbank, Los Angeles County, Calif.) 2023 Dec;116:112216
Nutrition (Burbank, Los Angeles County, Calif.) 2023 Dec;116:112216
Plasma-Activated Solutions Mitigates DSS-Induced Colitis via Restoring Redox Homeostasis and Reversing Microbiota Dysbiosis.
Sun T, Ren K, Xu G, Ma R, Wang X, Min T, Xie X, Sun A, Ma Y, Wang H, Zhang Y, Zhu K, Dang C, Zhang G, Zhang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304044
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304044
IGF2/IGF2R/Sting signaling as a therapeutic target in DSS-induced ulcerative colitis.
Chen L, Zhong XL, Cao WY, Mao ML, Liu DD, Liu WJ, Zu XY, Liu JH
European journal of pharmacology 2023 Dec 5;960:176122
European journal of pharmacology 2023 Dec 5;960:176122
Lactobacillus acidophilus JYLA-126 Ameliorates Obesity-Associated Metabolic Disorders by Positively Regulating the AMPK Signaling Pathway Through the Gut-Liver Axis.
Li P, He X, Feng E, Wei J, Tu H, Chen T
Probiotics and antimicrobial proteins 2023 Dec 5;
Probiotics and antimicrobial proteins 2023 Dec 5;
FGF21 alleviates endothelial mitochondrial damage and prevents BBB from disruption after intracranial hemorrhage through a mechanism involving SIRT6.
Wang R, Wang J, Zhang Z, Ma B, Sun S, Gao L, Gao G
Molecular medicine (Cambridge, Mass.) 2023 Dec 4;29(1):165
Molecular medicine (Cambridge, Mass.) 2023 Dec 4;29(1):165
Potential Toxicity and Mechanisms of T-2 and HT-2 Individually or in Combination on the Intestinal Barrier Function of Porcine Small Intestinal Epithelial Cells.
He W, Wang J, Han M, Wang L, Li L, Zhang J, Chen S, Guo J, Zhai X, Yang J
Toxins 2023 Dec 4;15(12)
Toxins 2023 Dec 4;15(12)
Bacterial butyrate mediates the anti-atherosclerotic effect of silybin.
Shen HR, Wang ZY, Shen Z, Liu TT, Guo YD, Gao TL, Guo HH, Han YX, Jiang JD
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115916
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec 31;169:115916
Red Cabbage Juice-Mediated Gut Microbiota Modulation Improves Intestinal Epithelial Homeostasis and Ameliorates Colitis.
Jean Wilson E, Sirpu Natesh N, Ghadermazi P, Pothuraju R, Prajapati DR, Pandey S, Kaifi JT, Dodam JR, Bryan JN, Lorson CL, Watrelot AA, Foster JM, Mansell TJ, Joshua Chan SH, Batra SK, Subbiah J, Rachagani S
International journal of molecular sciences 2023 Dec 30;25(1)
International journal of molecular sciences 2023 Dec 30;25(1)
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA.
Shi L, Wang Z, Rong J, Fei X, Li X, He B, Gong W, Qian J
Aging 2023 Dec 27;15(24):15183-15195
Aging 2023 Dec 27;15(24):15183-15195
p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP.
Ouyang H, Wu S, Li W, Grey MJ, Wu W, Hansen SH
Cell reports 2023 Dec 26;42(12):113486
Cell reports 2023 Dec 26;42(12):113486
Clostridium butyricum and Clostridium tyrobutyricum: angel or devil for necrotizing enterocolitis?
Tao R, Zong G, Pan Y, Li H, Cheng P, Deng R, Chen W, Wang A, Xia S, Tang W, Lu Y, Wei Z
mSystems 2023 Dec 21;8(6):e0073223
mSystems 2023 Dec 21;8(6):e0073223
Intrarectal Administration of Adelmidrol plus Hyaluronic Acid Gel Ameliorates Experimental Colitis in Mice and Inhibits Pro-Inflammatory Response in Ex Vivo Cultured Biopsies Derived from Ulcerative Colitis-Affected Patients.
Palenca I, Seguella L, Zilli A, Basili Franzin S, Del Re A, Pepi F, Troiani A, Pesce M, Rurgo S, De Palma FDE, Luglio G, Tropeano FP, Sarnelli G, Esposito G
International journal of molecular sciences 2023 Dec 21;25(1)
International journal of molecular sciences 2023 Dec 21;25(1)
Gut microbiota-associated taurine metabolism dysregulation in a mouse model of Parkinson's disease.
Cui C, Song H, Han Y, Yu H, Li H, Yang Y, Zhang B
mSphere 2023 Dec 20;8(6):e0043123
mSphere 2023 Dec 20;8(6):e0043123
Heat Stress-Induced Fetal Intrauterine Growth Restriction Is Associated with Elevated LPS Levels Along the Maternal Intestine-Placenta-Fetus Axis in Pregnant Mice.
Zheng X, Ma W, Wang Y, Wu C, Wang J, Ma Z, Wei Y, Cui C, Zhang S, Guan W, Chen F
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19592-19609
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19592-19609
The role of ROS-pyroptosis in PM(2.5) induced air-blood barrier destruction.
Wei M, Cong Y, Lei J, Du R, Yang M, Lu X, Jiang Y, Cao R, Meng X, Jiang Z, Song L
Chemico-biological interactions 2023 Dec 1;386:110782
Chemico-biological interactions 2023 Dec 1;386:110782
Maternal Selenium-Enriched Yeast Supplementation in Sows Enhances Offspring Growth and Antioxidant Status through the Nrf2/Keap1 Pathway.
Xiong L, Lin T, Yue X, Zhang S, Liu X, Chen F, Zhang S, Guan W
Antioxidants (Basel, Switzerland) 2023 Dec 1;12(12)
Antioxidants (Basel, Switzerland) 2023 Dec 1;12(12)
Pterostilbene could alleviate diabetic cognitive impairment by suppressing TLR4/NF-кB pathway through microbiota-gut-brain axis.
Zhang ZT, Deng SM, Chen C, He QH, Peng XW, Liang QF, Zhuang GD, Wang SM, Tang D
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
Phytotherapy research : PTR 2023 Aug;37(8):3522-3542
Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function.
Xia J, Li J, Deng M, Yin F, Liu J, Wang J
Inflammopharmacology 2023 Aug;31(4):2037-2047
Inflammopharmacology 2023 Aug;31(4):2037-2047
Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment.
Ge X, Wen H, Fei Y, Xue R, Cheng Z, Li Y, Cai K, Li L, Li M, Luo Z
Biomaterials 2023 Aug;299:122184
Biomaterials 2023 Aug;299:122184
Succinate signaling attenuates high-fat diet-induced metabolic disturbance and intestinal barrier dysfunction.
Li X, Huang G, Zhang Y, Ren Y, Zhang R, Zhu W, Yu K
Pharmacological research 2023 Aug;194:106865
Pharmacological research 2023 Aug;194:106865
Limosilactobacillus fermentum NCU003089 and Lactiplantibacillus plantarum NCU001261, two probiotics with inhibition of Escherichia coli and Cronobacter sakazakii translocation in vitro.
Wei B, Peng Z, Xiao M, Huang T, Zheng W, Xie M, Xiong T
Microbial pathogenesis 2023 Aug;181:106216
Microbial pathogenesis 2023 Aug;181:106216
Sphingosine 1-phosphate receptor 1 regulates blood-brain barrier permeability in epileptic mice.
Yang LX, Yao YY, Yang JR, Cheng HL, Zhu XJ, Zhang ZJ
Neural regeneration research 2023 Aug;18(8):1763-1769
Neural regeneration research 2023 Aug;18(8):1763-1769
Triclocarban exposure aggravates dextran sulfate sodium-induced colitis by deteriorating the gut barrier function and microbial community in mice.
Qin M, Lei H, Song Y, Wu M, Chen C, Cao Z, Zhang C, Du R, Zhang C, Wang X, Zhang L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Aug;178:113908
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Aug;178:113908
MiR-874-5p targets VDR/NLRP3 to reduce intestinal pyroptosis and improve intestinal barrier damage in sepsis.
Shang L, Li J, Zhou F, Zhang M, Wang S, Yang S
International immunopharmacology 2023 Aug;121:110424
International immunopharmacology 2023 Aug;121:110424
Extracellular ATP accelerates cell death and decreases tight junction protein ZO-1 in hypoxic cochlear strial marginal cells in neonatal rats.
Zhao Y, Huang S, Xie R, Liu J
Cellular signalling 2023 Aug;108:110732
Cellular signalling 2023 Aug;108:110732
Arula-7 powder improves diarrhea and intestinal epithelial tight junction function associated with its regulation of intestinal flora in calves infected with pathogenic Escherichia coli O(1).
Chen H, Jia Z, He M, Chen A, Zhang X, Xu J, Wang C
Microbiome 2023 Aug 5;11(1):172
Microbiome 2023 Aug 5;11(1):172
Mechanisms of Lung and Intestinal Microbiota and Innate Immune Changes Caused by Pathogenic Enterococcus Faecalis Promoting the Development of Pediatric Pneumonia.
Tian Z, Deng T, Gui X, Wang L, Yan Q, Wang L
Microorganisms 2023 Aug 31;11(9)
Microorganisms 2023 Aug 31;11(9)
Zinc-Rutin Particles Ameliorate DSS-Induced Acute and Chronic Colitis via Anti-inflammatory and Antioxidant Protection of the Intestinal Epithelial Barrier.
Wu W, Liu L, Zhu Y, Ni J, Lu J, Wang X, Ma L, Jiang Y
Journal of agricultural and food chemistry 2023 Aug 30;71(34):12715-12729
Journal of agricultural and food chemistry 2023 Aug 30;71(34):12715-12729
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids.
Wang X, Quan J, Xiu C, Wang J, Zhang J
Chinese medicine 2023 Aug 30;18(1):110
Chinese medicine 2023 Aug 30;18(1):110
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis.
Jean Wilson E, Sirpu Natesh N, Ghadermazi P, Pothuraju R, Shanmugam M, Prajapati DR, Pandey S, Kaifi JT, Dodam JR, Bryan J, Lorson CL, Watrelot AA, Foster JM, Mansel TJ, Joshua Chan SH, Batra SK, Subbiah J, Rachagani S
bioRxiv : the preprint server for biology 2023 Aug 24;
bioRxiv : the preprint server for biology 2023 Aug 24;
Dextran sulfate sodium-induced mild chronic colitis induced cognitive impairment accompanied by inhibition of neuronal maturation in adolescent mice.
Lee K, Kumazoe M, Marugame Y, Fujimura Y, Tachibana H
Biochemical and biophysical research communications 2023 Aug 20;669:46-53
Biochemical and biophysical research communications 2023 Aug 20;669:46-53
Role of omentin-1 in susceptibility to anxiety and depression like behaviors.
Ji L, Zhang L, Liang Z, Zhong S, Liu X, Liu Z, Poon WS, Song Y, Chen B, Wang R
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Molecular and cellular endocrinology 2023 Aug 20;574:111990
Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition.
Ma H, Zhang X, Liu L, Huang Y, Sun S, Chen K, Xin Q, Liu P, Yan Y, Wang Y, Li Y, Liu H, Zhao R, Tan K, Chen X, Yuan X, Li Y, Liu Y, Dai H, Liu C, Wang H, Zhang XD
Science advances 2023 Aug 2;9(31):eadh7828
Science advances 2023 Aug 2;9(31):eadh7828
Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability.
Hu J, Ding R, Liu S, Wang J, Li J, Shang Y
iScience 2023 Aug 18;26(8):107503
iScience 2023 Aug 18;26(8):107503
Mechanisms of Qingyi Decoction in Severe Acute Pancreatitis-Associated Acute Lung Injury via Gut Microbiota: Targeting the Short-Chain Fatty Acids-Mediated AMPK/NF-κB/NLRP3 Pathway.
Wang Z, Liu J, Li F, Ma S, Zhao L, Ge P, Wen H, Zhang Y, Liu X, Luo Y, Yao J, Zhang G, Chen H
Microbiology spectrum 2023 Aug 17;11(4):e0366422
Microbiology spectrum 2023 Aug 17;11(4):e0366422
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Wang Z, Tan C, Duan C, Wu J, Zhou D, Hou L, Qian W, Han C, Hou X
Redox biology 2023 Apr;60:102618
Redox biology 2023 Apr;60:102618
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice.
Wang S, Liu J, Cheng D, Ren L, Zheng L, Chen F, Zeng T
Toxicology 2023 Apr;488:153487
Toxicology 2023 Apr;488:153487
JP1, a polypeptide specifically targeting integrin αVβ3, ameliorates choroidal neovascularization and diabetic retinopathy in mice.
Xie Z, Wu XJ, Cheng RW, Cui JH, Yuan ST, Zhou JW, Liu QH
Acta pharmacologica Sinica 2023 Apr;44(4):897-912
Acta pharmacologica Sinica 2023 Apr;44(4):897-912
Intranasal Delivery of Gene-Edited Microglial Exosomes Improves Neurological Outcomes after Intracerebral Hemorrhage by Regulating Neuroinflammation.
Guo M, Ge X, Wang C, Yin Z, Jia Z, Hu T, Li M, Wang D, Han Z, Wang L, Xiong X, Chen F, Lei P
Brain sciences 2023 Apr 8;13(4)
Brain sciences 2023 Apr 8;13(4)
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Xie Z, Zhang G, Liu R, Wang Y, Tsapieva AN, Zhang L, Han J
Nutrients 2023 Apr 4;15(7)
Nutrients 2023 Apr 4;15(7)
Organotypic 3D Co-Culture of Human Pleura as a Novel In Vitro Model of Staphylococcus aureus Infection and Biofilm Development.
Kurow O, Nuwayhid R, Stock P, Steinert M, Langer S, Krämer S, Metelmann IB
Bioengineering (Basel, Switzerland) 2023 Apr 27;10(5)
Bioengineering (Basel, Switzerland) 2023 Apr 27;10(5)
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis.
Guo HH, Shen HR, Tang MZ, Sheng N, Ding X, Lin Y, Zhang JL, Jiang JD, Gao TL, Wang LL, Han YX
Journal of ethnopharmacology 2023 Apr 24;306:116158
Journal of ethnopharmacology 2023 Apr 24;306:116158
Huangkui capsule alleviates doxorubicin-induced proteinuria via protecting against podocyte damage and inhibiting JAK/STAT signaling.
Zhao L, Han S, Chai C
Journal of ethnopharmacology 2023 Apr 24;306:116150
Journal of ethnopharmacology 2023 Apr 24;306:116150
Periodontitis salivary microbiota exacerbates nonalcoholic fatty liver disease in high-fat diet-induced obese mice.
Wang M, Li L, Qian J, Wang N, Bao J, Lu J, Chen F, Li Y, Zhang Y, Yan F
iScience 2023 Apr 21;26(4):106346
iScience 2023 Apr 21;26(4):106346
Cadmium-induced Sertoli Cell Injury Through p38-MAPK and Related Signaling Proteins-A Study by RNA Sequencing.
Wang L, Li X, Bu T, Wu X, Li L, Gao S, Yun D, Zhang Y, Chen H, Sun F, Cheng CY
Endocrinology 2023 Apr 17;164(6)
Endocrinology 2023 Apr 17;164(6)
Lactational exposure to Deoxynivalenol causes mammary gland injury via inducing inflammatory response and impairing blood-milk barrier integrity in mice.
Sun P, Zhao X, Liu M, Wu H, Lv C, Zhou S, Ding Z, Huo L, Yang L, Liang A
Ecotoxicology and environmental safety 2023 Apr 15;255:114773
Ecotoxicology and environmental safety 2023 Apr 15;255:114773
Astragalus polysaccharides alleviate type 1 diabetes via modulating gut microbiota in mice.
Yang B, Xiong Z, Lin M, Yang Y, Chen Y, Zeng J, Jia X, Feng L
International journal of biological macromolecules 2023 Apr 15;234:123767
International journal of biological macromolecules 2023 Apr 15;234:123767
Mitochondrial-targeting fluorescent small molecule IR-780 alleviates radiation-induced brain injury.
Zhang C, Zheng J, Chen W, Yang W, Tan X, Fan X, Shen G, Qu L, Chen Z, Shi C
Brain research 2023 Apr 15;1805:148285
Brain research 2023 Apr 15;1805:148285
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Liu C, Lu J, Yuan T, Xie L, Zhang L
Scientific reports 2023 Apr 14;13(1):6126
Scientific reports 2023 Apr 14;13(1):6126
Construction of a three-dimensional urothelium on-chip with barrier function based on urinary flow microenvironment.
Hou C, Gu Y, Yuan W, Zhang W, Xiu X, Lin J, Gao Y, Liu P, Chen X, Song L
Biofabrication 2023 Apr 11;15(3)
Biofabrication 2023 Apr 11;15(3)
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Li J, Bai J, Si X, Jia H, Wu Z
Chemico-biological interactions 2023 Apr 1;374:110386
Chemico-biological interactions 2023 Apr 1;374:110386
Kinase Activity Is Not Required for G Protein-Coupled Receptor Kinase 4 Restraining mTOR Signaling during Cilia and Kidney Development.
Gerhards J, Maerz LD, Matthees ESF, Donow C, Moepps B, Premont RT, Burkhalter MD, Hoffmann C, Philipp M
Journal of the American Society of Nephrology : JASN 2023 Apr 1;34(4):590-606
Journal of the American Society of Nephrology : JASN 2023 Apr 1;34(4):590-606
A leaky human colon model reveals uncoupled apical/basal cytotoxicity in early Clostridioides difficile toxin exposure.
Ok MT, Liu J, Bliton RJ, Hinesley CM, San Pedro EET, Breau KA, Gomez-Martinez I, Burclaff J, Magness ST
American journal of physiology. Gastrointestinal and liver physiology 2023 Apr 1;324(4):G262-G280
American journal of physiology. Gastrointestinal and liver physiology 2023 Apr 1;324(4):G262-G280
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Yang Y, Zheng S, Chu H, Du C, Chen M, Emran MY, Chen J, Yang F, Tian L
Toxins 2023 Apr 1;15(4)
Toxins 2023 Apr 1;15(4)
Selenoprotein W Ameliorates Experimental Colitis and Promotes Intestinal Epithelial Repair.
Nettleford SK, Liao C, Short SP, Rossi RM, Singh V, Prabhu KS
Antioxidants (Basel, Switzerland) 2023 Apr 1;12(4)
Antioxidants (Basel, Switzerland) 2023 Apr 1;12(4)
Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model.
Rehman AU, Siddiqui NZ, Farooqui NA, Alam G, Gul A, Ahmad B, Asim M, Khan AI, Xin Y, Zexu W, Song Ju H, Xin W, Lei S, Wang L
Frontiers in nutrition 2022;9:984695
Frontiers in nutrition 2022;9:984695
Probiotic Lactobacillus rhamnosus GR-1 supplementation attenuates Pb-induced learning and memory deficits by reshaping the gut microbiota.
Gu X, Bi N, Wang T, Huang C, Wang R, Xu Y, Wang HL
Frontiers in nutrition 2022;9:934118
Frontiers in nutrition 2022;9:934118
Lactobacillus fermentum CECT5716 Alleviates the Inflammatory Response in Asthma by Regulating TLR2/TLR4 Expression.
Wang W, Li Y, Han G, Li A, Kong X
Frontiers in nutrition 2022;9:931427
Frontiers in nutrition 2022;9:931427
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
He C, Gao M, Zhang X, Lei P, Yang H, Qing Y, Zhang L
Frontiers in nutrition 2022;9:893344
Frontiers in nutrition 2022;9:893344
Green Banana Flour Contributes to Gut Microbiota Recovery and Improves Colonic Barrier Integrity in Mice Following Antibiotic Perturbation.
Li P, Li M, Song Y, Huang X, Wu T, Xu ZZ, Lu H
Frontiers in nutrition 2022;9:832848
Frontiers in nutrition 2022;9:832848
Blue Light Induces RPE Cell Necroptosis, Which Can Be Inhibited by Minocycline.
Song W, Zhu R, Gao W, Xing C, Yang L
Frontiers in medicine 2022;9:831463
Frontiers in medicine 2022;9:831463
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
Song Q, Chen P, Wu SJ, Chen Y, Zhang Y
Frontiers in cardiovascular medicine 2022;9:746888
Frontiers in cardiovascular medicine 2022;9:746888
Bacteroides fragilis strain ZY-312 promotes intestinal barrier integrity via upregulating the STAT3 pathway in a radiation-induced intestinal injury mouse model.
Zhou Q, Shen B, Huang R, Liu H, Zhang W, Song M, Liu K, Lin X, Chen S, Liu Y, Wang Y, Zhi F
Frontiers in nutrition 2022;9:1063699
Frontiers in nutrition 2022;9:1063699
Tannic acid attenuates intestinal oxidative damage by improving antioxidant capacity and intestinal barrier in weaned piglets and IPEC-J2 cells.
Wang M, Huang H, Wang L, Yin L, Yang H, Chen C, Zheng Q, He S
Frontiers in nutrition 2022;9:1012207
Frontiers in nutrition 2022;9:1012207
Calycosin Improves Intestinal Mucosal Barrier Function after Gastrectomy in Rats through Alleviating Bacterial Translocation, Inflammation, and Oxidative Stress.
Peng H, Jin L, Zhang Q, Shen Y, Wang Z, Zhou F, Yu Q
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7412331
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7412331
Nicotinamide Mononucleotide Ameliorates Cellular Senescence and Inflammation Caused by Sodium Iodate in RPE.
Ren C, Hu C, Wu Y, Li T, Zou A, Yu D, Shen T, Cai W, Yu J
Oxidative medicine and cellular longevity 2022;2022:5961123
Oxidative medicine and cellular longevity 2022;2022:5961123
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y, Wang J, Wang X, Zhang J, Shao A
Oxidative medicine and cellular longevity 2022;2022:4295208
Oxidative medicine and cellular longevity 2022;2022:4295208
Effects of Lipolysis-Stimulated Lipoprotein Receptor on Tight Junctions of Pancreatic Ductal Epithelial Cells in Hypertriglyceridemic Acute Pancreatitis.
Wang J, Qin M, Wu Q, Yang H, Wei B, Xie J, Qin Y, Liang Z, Huang J
BioMed research international 2022;2022:4234186
BioMed research international 2022;2022:4234186
Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway.
Niu S, Jing M, Wen J, Wei S, Li H, Li X, Ma X, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3498310
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3498310
Honokiol Ameliorates DSS-Induced Mouse Colitis by Inhibiting Inflammation and Oxidative Stress and Improving the Intestinal Barrier.
Wang L, Wang J
Oxidative medicine and cellular longevity 2022;2022:1755608
Oxidative medicine and cellular longevity 2022;2022:1755608
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
Li J, Yang T, Wang Q, Li Y, Wu H, Zhang M, Qi H, Zhang H, Li J
International journal of biological sciences 2022;18(9):3576-3591
International journal of biological sciences 2022;18(9):3576-3591
The effect of a fennel seed extract on the STAT signaling and intestinal barrier function.
Das B, Rabalais J, Kozan P, Lu T, Durali N, Okamoto K, McGeough MD, Lee BJ, Barrett KE, Marchelletta R, Sivagnanam M
PloS one 2022;17(7):e0271045
PloS one 2022;17(7):e0271045
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
Sun J, Zhang W
PloS one 2022;17(3):e0266084
PloS one 2022;17(3):e0266084
The SARS-CoV-2 envelope protein disrupts barrier function in an in vitro human blood-brain barrier model.
Ju J, Su Y, Zhou Y, Wei H, Xu Q
Frontiers in cellular neuroscience 2022;16:897564
Frontiers in cellular neuroscience 2022;16:897564
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage.
Guo H, Zhang W, Wang Z, Li Z, Zhou J, Yang Z
Frontiers in molecular neuroscience 2022;15:977941
Frontiers in molecular neuroscience 2022;15:977941
Selenium-enriched Bifidobacterium longum DD98 effectively ameliorates dextran sulfate sodium-induced ulcerative colitis in mice.
Hu Y, Jin X, Gao F, Lin T, Zhu H, Hou X, Yin Y, Kan S, Chen D
Frontiers in microbiology 2022;13:955112
Frontiers in microbiology 2022;13:955112
Preventive effects of the Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple on chronic kidney disease rats via modulating the intestinal microbiota and enhancing the intestinal barrier.
Wang L, Zhu JH, Jiang XD, Ma ZX, Tao JH
Frontiers in pharmacology 2022;13:942032
Frontiers in pharmacology 2022;13:942032
Polysaccharide, the Active Component of Dendrobium officinale, Ameliorates Metabolic Hypertension in Rats via Regulating Intestinal Flora-SCFAs-Vascular Axis.
Li B, Wang HY, Huang JH, Xu WF, Feng XJ, Xiong ZP, Dong YJ, Li LZ, He X, Wu HS, Zhang K, Su J, Yu QX, Jiang NH, Lv GY, Chen SH
Frontiers in pharmacology 2022;13:935714
Frontiers in pharmacology 2022;13:935714
Intestinal Flora-Derived Kynurenic Acid Protects Against Intestinal Damage Caused by Candida albicans Infection via Activation of Aryl Hydrocarbon Receptor.
Wang Z, Yin L, Qi Y, Zhang J, Zhu H, Tang J
Frontiers in microbiology 2022;13:934786
Frontiers in microbiology 2022;13:934786
Eugenol alleviates transmissible gastroenteritis virus-induced intestinal epithelial injury by regulating NF-κB signaling pathway.
Wang K, Chen D, Yu B, He J, Mao X, Huang Z, Yan H, Wu A, Luo Y, Zheng P, Yu J, Luo J
Frontiers in immunology 2022;13:921613
Frontiers in immunology 2022;13:921613
Tryptophan Supplementation Enhances Intestinal Health by Improving Gut Barrier Function, Alleviating Inflammation, and Modulating Intestinal Microbiome in Lipopolysaccharide-Challenged Piglets.
Liu G, Lu J, Sun W, Jia G, Zhao H, Chen X, Kim IH, Zhang R, Wang J
Frontiers in microbiology 2022;13:919431
Frontiers in microbiology 2022;13:919431
Qingchang Wenzhong Decoction Prevents the Occurrence of Intestinal Tumors by Regulating Intestinal Microbiota and Gasdermin E.
Ren L, Zhang Z, Zhao W, Zhao B, Chen X, Wang Y, Chen Z, Ye J, Yang Y, Cao P
Frontiers in physiology 2022;13:917323
Frontiers in physiology 2022;13:917323
Integrated analysis of inflammatory response subtype-related signature to predict clinical outcomes, immune status and drug targets in lower-grade glioma.
Cao Y, Zhu H, Chen Q, Huang H, Xie D, Li X, Jiang X, Ren C, Peng J
Frontiers in pharmacology 2022;13:914667
Frontiers in pharmacology 2022;13:914667
Effect of Tanshinone IIA on Gut Microbiome in Diabetes-Induced Cognitive Impairment.
Zheng Y, Zhou X, Wang C, Zhang J, Chang D, Liu W, Zhu M, Zhuang S, Shi H, Wang X, Chen Y, Cheng Z, Lin Y, Nan L, Sun Y, Min L, Liu J, Chen J, Zhang J, Huang M
Frontiers in pharmacology 2022;13:890444
Frontiers in pharmacology 2022;13:890444
Shenling Baizhu Powder Alleviates TNBS-Induced Colitis in Rats by Improving Intestinal Epithelial Permeability and Inhibiting Inflammation Through the TLR5/MyD88/NF-κB Pathway.
Rao K, Qin S, Yang Y, Zhan K, Wu H, Zheng H, Huang S
Frontiers in pharmacology 2022;13:883918
Frontiers in pharmacology 2022;13:883918
Transepithelial Secretion of Mucosal IgM Mediated by Polymeric Immunoglobulin Receptor of Flounder (Paralichthys olivaceus): In-Vivo and In-Vitro Evidence.
Sheng X, Guo Y, Zhu H, Chai B, Tang X, Xing J, Chi H, Zhan W
Frontiers in immunology 2022;13:868753
Frontiers in immunology 2022;13:868753
Artemisinin analog SM934 alleviates epithelial barrier dysfunction via inhibiting apoptosis and caspase-1-mediated pyroptosis in experimental colitis.
Shao M, Yan Y, Zhu F, Yang X, Qi Q, Yang F, Hao T, Lin Z, He P, Zhou Y, Tang W, He S, Zuo J
Frontiers in pharmacology 2022;13:849014
Frontiers in pharmacology 2022;13:849014
Human Fecal Microbiota Transplantation Reduces the Susceptibility to Dextran Sulfate Sodium-Induced Germ-Free Mouse Colitis.
Yang Y, Zheng X, Wang Y, Tan X, Zou H, Feng S, Zhang H, Zhang Z, He J, Cui B, Zhang X, Wu Z, Dong M, Cheng W, Tao S, Wei H
Frontiers in immunology 2022;13:836542
Frontiers in immunology 2022;13:836542
S1PR3, as a Core Protein Related to Ischemic Stroke, is Involved in the Regulation of Blood-Brain Barrier Damage.
Fan X, Chen H, Xu C, Wang Y, Yin P, Li M, Tang Z, Jiang F, Wei W, Song J, Li G, Zhong D
Frontiers in pharmacology 2022;13:834948
Frontiers in pharmacology 2022;13:834948
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Zhang R, Xie L, Wu F, Xu J, Lu L, Cao L, Li L, Meng W, Zhang H, Shao C, Li X, Chen D
Frontiers in pharmacology 2022;13:828896
Frontiers in pharmacology 2022;13:828896
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348
Frontiers in physiology 2022;13:822348
Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis.
Ghosh S, Moorthy B, Haribabu B, Jala VR
Frontiers in immunology 2022;13:1004603
Frontiers in immunology 2022;13:1004603
Microbial metabolite restricts 5-fluorouracil-resistant colonic tumor progression by sensitizing drug transporters via regulation of FOXO3-FOXM1 axis.
Ghosh S, Singh R, Vanwinkle ZM, Guo H, Vemula PK, Goel A, Haribabu B, Jala VR
Theranostics 2022;12(12):5574-5595
Theranostics 2022;12(12):5574-5595
Liujunanwei decoction attenuates cisplatin-induced nausea and vomiting in a Rat-Pica model partially mediated by modulating the gut micsrobiome.
Chen D, Guo Y, Yang Y
Frontiers in cellular and infection microbiology 2022;12:876781
Frontiers in cellular and infection microbiology 2022;12:876781
Correlation Analysis of Gut Microbiota and Serum Metabolome With Porphyromonas gingivalis-Induced Metabolic Disorders.
Dong Z, Lv W, Zhang C, Chen S
Frontiers in cellular and infection microbiology 2022;12:858902
Frontiers in cellular and infection microbiology 2022;12:858902
Effects of Zhishi Daozhi Decoction on the intestinal flora of nonalcoholic fatty liver disease mice induced by a high-fat diet.
Bi CR, Sun JT, Du J, Chu LY, Li YJ, Jia XY, Liu Y, Zhang WP, Li YC, Liu YJ
Frontiers in cellular and infection microbiology 2022;12:1005318
Frontiers in cellular and infection microbiology 2022;12:1005318
Telomerase reverse transcriptase promotes angiogenesis in neonatal rats after hypoxic-ischemic brain damage.
Li J, Feng Y, Zhao J, Fang Z, Liu H
PeerJ 2022;10:e14220
PeerJ 2022;10:e14220
A Platform for Co-Culture of Primary Human Colonic Epithelium With Anaerobic Probiotic Bacteria.
Kim R, Wang Y, Sims CE, Allbritton NL
Frontiers in bioengineering and biotechnology 2022;10:890396
Frontiers in bioengineering and biotechnology 2022;10:890396
Discoidin domain receptor 1(DDR1) promote intestinal barrier disruption in Ulcerative Colitis through tight junction proteins degradation and epithelium apoptosis.
Li X, Li Q, Xiong B, Chen H, Wang X, Zhang D
Pharmacological research 2022 Sep;183:106368
Pharmacological research 2022 Sep;183:106368
Complement factor B inhibitor LNP023 improves lupus nephritis in MRL/lpr mice.
Chen K, Deng Y, Shang S, Tang L, Li Q, Bai X, Chen X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113433
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113433
Cortex periplocae modulates the gut microbiota to restrict colitis and colitis-associated colorectal cancer via suppression of pathogenic Th17 cells.
Lin Z, Chen L, Cheng M, Zhu F, Yang X, Zhao W, Zuo J, He S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113399
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113399
Exercise protects intestinal epithelial barrier from high fat diet- induced permeabilization through SESN2/AMPKα1/HIF-1α signaling.
Yu C, Liu S, Niu Y, Fu L
The Journal of nutritional biochemistry 2022 Sep;107:109059
The Journal of nutritional biochemistry 2022 Sep;107:109059
Glutamine in suppression of lipopolysaccharide-induced piglet intestinal inflammation: The crosstalk between AMPK activation and mitochondrial function.
He L, Zhou X, Wu Z, Feng Y, Liu D, Li T, Yin Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:137-147
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:137-147
Gut microbiota-derived metabolites contribute negatively to hindgut barrier function development at the early weaning goat model.
Zhang K, Xu Y, Yang Y, Guo M, Zhang T, Zong B, Huang S, Suo L, Ma B, Wang X, Wu Y, Brugger D, Chen Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:111-123
Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions.
Shan Q, Liu N, Wang X, Zhu Y, Yin J, Wang J
Journal of animal science and biotechnology 2022 Sep 9;13(1):101
Journal of animal science and biotechnology 2022 Sep 9;13(1):101
Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities.
Zhao Y, Zhang T, Shen X, Huang A, Li H, Wang L, Liu X, Wang X, Song X, Wang S, Dong J, Shao N
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Sep 7;30(9):3052-3065
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Sep 7;30(9):3052-3065
Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota.
Rehman AU, Khan AI, Xin Y, Liang W
AMB Express 2022 Sep 3;12(1):114
AMB Express 2022 Sep 3;12(1):114
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice.
Siddiqui NZ, Rehman AU, Yousuf W, Khan AI, Farooqui NA, Zang S, Xin Y, Wang L
Gut pathogens 2022 Sep 17;14(1):39
Gut pathogens 2022 Sep 17;14(1):39
Protective Effects and Mechanism of a Novel Probiotic Strain Ligilactobacillus salivarius YL20 against Cronobacter sakazakii-Induced Necrotizing Enterocolitis In Vitro and In Vivo.
Wang W, Geng M, Zhu C, Huang L, Zhang Y, Zhang T, Zhao C, Zhang T, Du X, Wang N
Nutrients 2022 Sep 16;14(18)
Nutrients 2022 Sep 16;14(18)
Effect and Mechanism of Pharmaceutical Excipients on Berberine to Alleviate Ulcerative Colitis via Regulating Gut Microbiota.
Wu C, Zheng T, Chen H, Zou P, Zhang M, Wang J, Li N, Zhang Y, Li Y, Dong Z
Molecules (Basel, Switzerland) 2022 Sep 15;27(18)
Molecules (Basel, Switzerland) 2022 Sep 15;27(18)
Phytic Acid Improves Hepatic Steatosis, Inflammation, and Oxidative Stress in High-Fat Diet (HFD)-Fed Mice by Modulating the Gut-Liver Axis.
Ran X, Hu G, He F, Li K, Li F, Xu D, Liu J, Fu S
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11401-11411
Journal of agricultural and food chemistry 2022 Sep 14;70(36):11401-11411
Periplaneta americana Extract Pretreatment Alleviates Oxidative Stress and Inflammation and Increases the Abundance of Gut Akkermansia muciniphila in Diquat-Induced Mice.
Lu S, Xu S, Chen L, Deng Y, Feng J
Antioxidants (Basel, Switzerland) 2022 Sep 13;11(9)
Antioxidants (Basel, Switzerland) 2022 Sep 13;11(9)
Mo(3)Se(4) nanoparticle with ROS scavenging and multi-enzyme activity for the treatment of DSS-induced colitis in mice.
Guo H, Guo H, Xie Y, Chen Y, Lu C, Yang Z, Zhu Y, Ouyang Y, Zhang Y, Wang X
Redox biology 2022 Oct;56:102441
Redox biology 2022 Oct;56:102441
TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α.
Xie H, Shi Y, Zhou Y, Liu H
Molecular biology reports 2022 Oct;49(10):9181-9194
Molecular biology reports 2022 Oct;49(10):9181-9194
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Liping Y, Xinglin YU, Chao Z, Pu C, Xiaohua D
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):707-714
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):707-714
Chromatin remodeler Znhit1 controls bone morphogenetic protein signaling in embryonic lung tissue branching.
Wei W, Tang X, Jiang N, Ni C, He H, Sun S, Yu M, Yu C, Qiu M, Yan D, Zhou Z, Song Y, Liu H, Zhao B, Lin X
The Journal of biological chemistry 2022 Oct;298(10):102490
The Journal of biological chemistry 2022 Oct;298(10):102490
Cold exposure-induced endoplasmic reticulum stress regulates autophagy through the SIRT2/FoxO1 signaling pathway.
Guo J, Nie J, Chen Z, Wang X, Hu H, Xu J, Lu J, Ma L, Ji H, Yuan J, Xu B
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Journal of cellular physiology 2022 Oct;237(10):3960-3970
Bisdemethoxycurcumin Alleviates Dextran Sodium Sulfate-Induced Colitis via Inhibiting NLRP3 Inflammasome Activation and Modulating the Gut Microbiota in Mice.
Zhang J, Li Q, Zhang X, Chen Y, Lu Y, Wang X, Zhang L, Wang T
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
Antioxidants (Basel, Switzerland) 2022 Oct 7;11(10)
Rice Protein Peptides Alleviate Dextran Sulfate Sodium-Induced Colitis via the Keap1-Nrf2 Signaling Pathway and Regulating Gut Microbiota.
Yang W, Huang Z, Xiong H, Wang J, Zhang H, Guo F, Wang C, Sun Y
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12469-12483
Journal of agricultural and food chemistry 2022 Oct 5;70(39):12469-12483
Injectable and reactive oxygen species-scavenging gelatin hydrogel promotes neural repair in experimental traumatic brain injury.
Zhang D, Chang R, Ren Y, He Y, Guo S, Guan F, Yao M
International journal of biological macromolecules 2022 Oct 31;219:844-863
International journal of biological macromolecules 2022 Oct 31;219:844-863
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT
iScience 2022 Oct 21;25(10):105050
iScience 2022 Oct 21;25(10):105050
Network Pharmacology Analysis and Experimental Validation of Kaempferol in the Treatment of Ischemic Stroke by Inhibiting Apoptosis and Regulating Neuroinflammation Involving Neutrophils.
Zhang SS, Liu M, Liu DN, Shang YF, Du GH, Wang YH
International journal of molecular sciences 2022 Oct 21;23(20)
International journal of molecular sciences 2022 Oct 21;23(20)
Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema.
Xue Y, Wang X, Wan B, Wang D, Li M, Cheng K, Luo Q, Wang D, Lu Y, Zhu L
Cell communication and signaling : CCS 2022 Oct 17;20(1):160
Cell communication and signaling : CCS 2022 Oct 17;20(1):160
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
Zhong X, Chen Z, Wang Y, Mao M, Deng Y, Shi M, Xu Y, Chen L, Cao W
Brain research bulletin 2022 Oct 15;189:174-183
Brain research bulletin 2022 Oct 15;189:174-183
The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice.
Zhou W, Wu WH, Si ZL, Liu HL, Wang H, Jiang H, Liu YF, Alolga RN, Chen C, Liu SJ, Bian XY, Shan JJ, Li J, Tan NH, Zhang ZH
Nature communications 2022 Oct 14;13(1):6081
Nature communications 2022 Oct 14;13(1):6081
Restored intestinal integrity, nutrients transporters, energy metabolism, antioxidative capacity and decreased harmful microbiota were associated with IUGR piglet's catch-up growth before weanling.
Cui C, Wu C, Wang J, Ma Z, Zheng X, Zhu P, Wang N, Zhu Y, Guan W, Chen F
Journal of animal science and biotechnology 2022 Oct 14;13(1):129
Journal of animal science and biotechnology 2022 Oct 14;13(1):129
Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.
Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J
Human molecular genetics 2022 Oct 10;31(20):3504-3520
Human molecular genetics 2022 Oct 10;31(20):3504-3520
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Yu R, Zhong J, Zhou Q, Ren W, Liu Z, Bian Y
Chemico-biological interactions 2022 Oct 1;366:110135
Chemico-biological interactions 2022 Oct 1;366:110135
Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice.
Cai G, Wu C, Mao N, Song Z, Yu L, Zhu T, Peng S, Yang Y, Liu Z, Wang D
International journal of biological macromolecules 2022 Oct 1;218:356-367
International journal of biological macromolecules 2022 Oct 1;218:356-367
P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy.
Huang L, Chen Y, Liu R, Li B, Fei X, Li X, Liu G, Li Y, Xu B, Fang W
Aging and disease 2022 Oct 1;13(5):1546-1561
Aging and disease 2022 Oct 1;13(5):1546-1561
Betaine Ameliorates Acute Sever Ulcerative Colitis by Inhibiting Oxidative Stress Induced Inflammatory Pyroptosis.
Chen L, Liu D, Mao M, Liu W, Wang Y, Liang Y, Cao W, Zhong X
Molecular nutrition & food research 2022 Nov;66(22):e2200341
Molecular nutrition & food research 2022 Nov;66(22):e2200341
Suspended Collagen Hydrogels to Replicate Human Colonic Epithelial Cell Interactions with Immune Cells.
Hinman SS, Massaro A, Wang Y, Sims CE, Kim R, Allbritton NL
Advanced biology 2022 Nov;6(11):e2200129
Advanced biology 2022 Nov;6(11):e2200129
Metabolites of Latilactobacillus curvatus BYB3 and Indole Activate Aryl Hydrocarbon Receptor to Attenuate Lipopolysaccharide-Induced Intestinal Barrier Dysfunction.
Wang X, Yong CC, Oh S
Food science of animal resources 2022 Nov;42(6):1046-1060
Food science of animal resources 2022 Nov;42(6):1046-1060
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Wang B, Zhang H, Chen YF, Hu LQ, Tian YY, Tong HW, Wang G, Chen C, Yuan P
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Detection of the role of intestinal flora and tryptophan metabolism involved in antidepressant-like actions of crocetin based on a multi-omics approach.
Lin S, Li Q, Xu Z, Chen Z, Tao Y, Tong Y, Wang T, Chen S, Wang P
Psychopharmacology 2022 Nov;239(11):3657-3677
Psychopharmacology 2022 Nov;239(11):3657-3677
Neutrophil extracellular traps: A novel therapeutic target for intracranial hemorrhage.
Jin J, Zhao X, Li W, Wang F, Tian J, Wang N, Gao X, Zhang J, Wu J, Mang G, Ma R, Hu S
Thrombosis research 2022 Nov;219:1-13
Thrombosis research 2022 Nov;219:1-13
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Zhan L, Zheng J, Meng J, Fu D, Pang L, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113778
Xiaojianzhong decoction attenuates gastric mucosal injury by activating the p62/Keap1/Nrf2 signaling pathway to inhibit ferroptosis.
Chen J, Zhang J, Chen T, Bao S, Li J, Wei H, Hu X, Liang Y, Liu F, Yan S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113631
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Nov;155:113631
Luteolin alleviates ulcerative colitis by restoring the balance of NCR(-)ILC3/NCR(+)ILC3 to repairing impaired intestinal barrier.
Xie X, Zhao M, Huang S, Li P, Chen P, Luo X, Wang Q, Pan Z, Li X, Chen J, Chen B, Zhou L
International immunopharmacology 2022 Nov;112:109251
International immunopharmacology 2022 Nov;112:109251
Magnolol limits NFκB-dependent inflammation by targeting PPARγ relieving retinal ischemia/reperfusion injury.
Wang N, Yang Y, Liu Y, Huang L, Gu M, Wu Y, Xu L, Sun H, Guo W
International immunopharmacology 2022 Nov;112:109242
International immunopharmacology 2022 Nov;112:109242
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Hypoxia-Induced HIF-1α Expression Promotes Neurogenic Bladder Fibrosis via EMT and Pyroptosis.
Li Q, Hong Y, Chen J, Zhou X, Tian X, Yu Y, Shen L, Long C, Cai M, Wu S, Wei G
Cells 2022 Nov 29;11(23)
Cells 2022 Nov 29;11(23)
Regulation of ZO-1 on β-catenin mediates sulforaphane suppressed colorectal cancer stem cell properties in colorectal cancer.
Chen Y, Tang L, Ye X, Chen Y, Shan E, Han H, Zhong C
Food & function 2022 Nov 28;13(23):12363-12370
Food & function 2022 Nov 28;13(23):12363-12370
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Song K, Yang X, An G, Xia X, Zhao J, Xu X, Wan C, Liu T, Zheng Y, Ren S, Wang M, Chang G, Cronin SJF, Penninger JM, Jing T, Ou X, Rao S, Liu Z, Zhao XY
Nature communications 2022 Nov 28;13(1):7335
Nature communications 2022 Nov 28;13(1):7335
New Baitouweng decoction combined with fecal microbiota transplantation alleviates DSS-induced colitis in rats by regulating gut microbiota metabolic homeostasis and the STAT3/NF-κB signaling pathway.
Gu X, Miao Z, Wang Y, Yang Y, Yang T, Xu Y
BMC complementary medicine and therapies 2022 Nov 24;22(1):307
BMC complementary medicine and therapies 2022 Nov 24;22(1):307
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
Xu D, Zhuang L, Gao S, Ma H, Cheng J, Liu J, Liu D, Fu S, Hu G
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14718-14731
Journal of agricultural and food chemistry 2022 Nov 23;70(46):14718-14731
FGF2 isoforms play distinct roles in tubular epithelial-to-mesenchymal transition in diabetic nephropathy.
Luo Y, Deng D, Lin L, Zhou Y, Wang L, Zou X, Wang X
Experimental cell research 2022 Nov 15;420(2):113355
Experimental cell research 2022 Nov 15;420(2):113355
Gestational PCB52 exposure induces hepatotoxicity and intestinal injury by activating inflammation in dam and offspring mice: A maternal and progeny study.
Xu LL, Zhang QY, Chen YK, Chen LJ, Zhang KK, Wang Q, Xie XL
Environmental pollution (Barking, Essex : 1987) 2022 Nov 15;313:120186
Environmental pollution (Barking, Essex : 1987) 2022 Nov 15;313:120186
DHA-enriched phosphatidylcholine from Clupea harengus roes regulates the gut-liver axis to ameliorate high-fat diet-induced non-alcoholic fatty liver disease.
Qian L, Tian S, Jiang S, Tang Y, Han T
Food & function 2022 Nov 14;13(22):11555-11567
Food & function 2022 Nov 14;13(22):11555-11567
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Li T, Zhai D, Zhang M, Ye R, Kuang X, Shao N, Bi J, Lin Y
Cancer letters 2022 Nov 1;548:215904
Cancer letters 2022 Nov 1;548:215904
Minocycline Pretreatment Prevents Blood-Brain Barrier Disruption in Septic Rats.
Yang G, Cao Y, Wang P, Mei L, Chen J, Lu W
The Journal of surgical research 2022 May;273:247-254
The Journal of surgical research 2022 May;273:247-254
Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury.
Zhao R, Wu X, Bi XY, Yang H, Zhang Q
Neural regeneration research 2022 May;17(5):1080-1087
Neural regeneration research 2022 May;17(5):1080-1087
Galactooligosaccharides as a protective agent for intestinal barrier and its regulatory functions for intestinal microbiota.
Wang G, Wang H, Jin Y, Xiao Z, Umar Yaqoob M, Lin Y, Chen H, Wang M
Food research international (Ottawa, Ont.) 2022 May;155:111003
Food research international (Ottawa, Ont.) 2022 May;155:111003
Effect of dendrobium mixture in alleviating diabetic cognitive impairment associated with regulating gut microbiota.
Zheng Y, Zhou X, Wang C, Zhang J, Chang D, Zhuang S, Xu W, Chen Y, Wang X, Nan L, Sun Y, Lin X, Lin W, He C, Dai L, Zhang J, Chen J, Shi H, Huang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112891
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112891
Comparison of five diarrhea-predominant irritable bowel syndrome (IBS-D) rat models in the brain-gut-microbiota axis.
Wu H, Zhan K, Rao K, Zheng H, Qin S, Tang X, Huang S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112811
miR-145-5p targets MMP2 to protect brain injury in hypertensive intracerebral hemorrhage via inactivation of the Wnt/β-catenin signaling pathway.
Xiao W, Jiang Z, Wan W, Pan W, Xu J
Annals of translational medicine 2022 May;10(10):571
Annals of translational medicine 2022 May;10(10):571
Human branching cholangiocyte organoids recapitulate functional bile duct formation.
Roos FJM, van Tienderen GS, Wu H, Bordeu I, Vinke D, Albarinos LM, Monfils K, Niesten S, Smits R, Willemse J, Rosmark O, Westergren-Thorsson G, Kunz DJ, de Wit M, French PJ, Vallier L, IJzermans JNM, Bartfai R, Marks H, Simons BD, van Royen ME, Verstegen MMA, van der Laan LJW
Cell stem cell 2022 May 5;29(5):776-794.e13
Cell stem cell 2022 May 5;29(5):776-794.e13
Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.
Zhang K, Lian S, Shen X, Zhao X, Zhao W, Li C
International journal of biological macromolecules 2022 May 31;208:890-900
International journal of biological macromolecules 2022 May 31;208:890-900
JAC4 Protects from X-ray Radiation-Induced Intestinal Injury by JWA-Mediated Anti-Oxidation/Inflammation Signaling.
Zhou Y, Liu J, Li X, Wang L, Hu L, Li A, Zhou J
Antioxidants (Basel, Switzerland) 2022 May 27;11(6)
Antioxidants (Basel, Switzerland) 2022 May 27;11(6)
Chromogranin A-derived peptide CGA47-66 protects against septic brain injury by reducing blood-brain barrier damage through the PI3K/AKT pathway.
Wang F, Zeng Y, Liu X, Cao J, Kang S, Zhou W, Chen X, Liu J, Zhang D
Biochemical and biophysical research communications 2022 May 21;605:162-170
Biochemical and biophysical research communications 2022 May 21;605:162-170
Methamphetamine induces intestinal injury by altering gut microbiota and promoting inflammation in mice.
Wang LB, Xu LL, Chen LJ, Zhang KK, Zhang QY, Chen YK, Li JH, Liu JL, Wang Q, Xie XL
Toxicology and applied pharmacology 2022 May 15;443:116011
Toxicology and applied pharmacology 2022 May 15;443:116011
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
Li J, Li Y, Liu P, Wang X, Ma Y, Zhong Q, Yang Q
Journal of virology 2022 May 11;96(9):e0038022
Journal of virology 2022 May 11;96(9):e0038022
Phloretin Protects Bovine Rumen Epithelial Cells from LPS-Induced Injury.
Wang K, Lei Q, Ma H, Jiang M, Yang T, Ma Q, Datsomor O, Zhan K, Zhao G
Toxins 2022 May 11;14(5)
Toxins 2022 May 11;14(5)
Gestational exposure to GenX induces hepatic alterations by the gut-liver axis in maternal mice: A similar mechanism as PFOA.
Xu LL, Chen YK, Zhang QY, Chen LJ, Zhang KK, Li JH, Liu JL, Wang Q, Xie XL
The Science of the total environment 2022 May 10;820:153281
The Science of the total environment 2022 May 10;820:153281
Ganluyin ameliorates DSS-induced ulcerative colitis by inhibiting the enteric-origin LPS/TLR4/NF-κB pathway.
Xiong T, Zheng X, Zhang K, Wu H, Dong Y, Zhou F, Cheng B, Li L, Xu W, Su J, Huang J, Jiang Z, Li B, Zhang B, Lv G, Chen S
Journal of ethnopharmacology 2022 May 10;289:115001
Journal of ethnopharmacology 2022 May 10;289:115001
Astilbin from Smilax glabra Roxb. alleviates high-fat diet-induced metabolic dysfunction.
Wang T, Ye Y, Ji J, Zhang S, Yang X, Xu J, Wang JS, Chen Z, Xia B, Shen H, Xia R, Shi W, Sun X
Food & function 2022 May 10;13(9):5023-5036
Food & function 2022 May 10;13(9):5023-5036
Diet composition affects long-term zearalenone exposure on the gut-blood-liver axis metabolic dysfunction in mice.
Wang T, Ye Y, Ji J, Yang X, Xu J, Wang JS, Han X, Zhang T, Sun X
Ecotoxicology and environmental safety 2022 May 1;236:113466
Ecotoxicology and environmental safety 2022 May 1;236:113466
Moutan Cortex polysaccharide ameliorates diabetic kidney disease via modulating gut microbiota dynamically in rats.
Zhang M, Yang L, Zhu M, Yang B, Yang Y, Jia X, Feng L
International journal of biological macromolecules 2022 May 1;206:849-860
International journal of biological macromolecules 2022 May 1;206:849-860
Dietary ferulic acid and vanillic acid on inflammation, gut barrier function and growth performance in lipopolysaccharide-challenged piglets.
Hu R, Wu S, Li B, Tan J, Yan J, Wang Y, Tang Z, Liu M, Fu C, Zhang H, He J
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):144-152
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Mar;8(1):144-152
Map, but not EspF, induces breast epithelial cell apoptosis through ERK/DRP-1 pathway.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J
Veterinary microbiology 2022 Mar;266:109367
Veterinary microbiology 2022 Mar;266:109367
Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats.
Yang R, Shen YJ, Chen M, Zhao JY, Chen SH, Zhang W, Song JK, Li L, Du GH
Journal of Asian natural products research 2022 Mar;24(3):278-289
Journal of Asian natural products research 2022 Mar;24(3):278-289
M1 macrophages impair tight junctions between endothelial cells after spinal cord injury.
Luo Y, Yao F, Hu X, Li Y, Chen Y, Li Z, Zhu Z, Yu S, Tian D, Cheng L, Zheng M, Jing J
Brain research bulletin 2022 Mar;180:59-72
Brain research bulletin 2022 Mar;180:59-72
Alterations in the expression level of visfatin in the lungs of piglets infected with PRRSV and its effect on PRRSV replication.
Zhang ZW, Ansari AR, Dong L, Niu XY, Yang WJ, Li HZ, Xu FL, Yang KL, Song H
Microbial pathogenesis 2022 Mar;164:105443
Microbial pathogenesis 2022 Mar;164:105443
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
Tan C, Fan H, Ding J, Han C, Guan Y, Zhu F, Wu H, Liu Y, Zhang W, Hou X, Tan S, Tang Q
Materials today. Bio 2022 Mar;14:100246
Materials today. Bio 2022 Mar;14:100246
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Du L, Hao YM, Yang YH, Zheng Y, Wu ZJ, Zhou MQ, Wang BZ, Wang YM, Wu H, Su GH
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2911-2922
Journal of agricultural and food chemistry 2022 Mar 9;70(9):2911-2922
Apple polyphenol extract modulates bile acid metabolism and gut microbiota by regulating the circadian rhythms in daytime-restricted high fat diet feeding C57BL/6 male mice.
Cui Y, Yin Y, Li S, Wu Z, Xie Y, Qian Q, Yang H, Li X
Food & function 2022 Mar 7;13(5):2805-2822
Food & function 2022 Mar 7;13(5):2805-2822
Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway.
Hu J, Wang X, Chen X, Fang Y, Chen K, Peng W, Wang Z, Guo K, Tan X, Liang F, Lin L, Xiong Y
Journal of neuroinflammation 2022 Mar 28;19(1):71
Journal of neuroinflammation 2022 Mar 28;19(1):71
Bioactive triple peptide inhibits inflammasome activation to alleviate Salmonella-induced intestinal inflammation in mice via modulation of host defense and bacterial virulence.
Cui C, Liu Q, Duan B, Liu X, Wei H, Peng J
Food & function 2022 Mar 21;13(6):3512-3525
Food & function 2022 Mar 21;13(6):3512-3525
Effect of TRAF6 in acute pancreatitis-induced intestinal barrier injury via TLR4/NF-κB signal pathway.
Wei B, Wu Q, Yang X, Lai C, Su Z, Liang Z
Tissue & cell 2022 Jun;76:101792
Tissue & cell 2022 Jun;76:101792
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Liu C, Sun W, Zhu T, Shi S, Zhang J, Wang J, Gao F, Ou Q, Jin C, Li J, Xu JY, Zhang J, Tian H, Xu GT, Lu L
Redox biology 2022 Jun;52:102292
Redox biology 2022 Jun;52:102292
Inhibition of galectin-3 ameliorates high-glucose-induced oxidative stress and inflammation in ARPE-19 cells.
Li M, Tian M, Jiang X, Liu Y, Wang Y, Li Y
Cutaneous and ocular toxicology 2022 Jun;41(2):179-186
Cutaneous and ocular toxicology 2022 Jun;41(2):179-186
Effects of dietary lycopene supplementation on intestinal morphology, antioxidant capability and inflammatory response in finishing pigs.
Liu A, Chen X, Huang Z, Chen D, Yu B, Chen H, He J, Yan H, Zheng P, Yu J, Luo Y
Animal biotechnology 2022 Jun;33(3):563-570
Animal biotechnology 2022 Jun;33(3):563-570
DEHP induces ferroptosis in testes via p38α-lipid ROS circulation and destroys the BTB integrity.
Yang L, Jiang L, Sun X, Li J, Wang N, Liu X, Yao X, Zhang C, Deng H, Wang S, Yang G
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113046
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113046
Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis.
Sun P, Zhang C, Huang Y, Yang J, Zhou F, Zeng J, Lin Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112975
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112975
In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation.
Zhang D, Ren Y, He Y, Chang R, Guo S, Ma S, Guan F, Yao M
Materials today. Bio 2022 Jun;15:100278
Materials today. Bio 2022 Jun;15:100278
Aryl-hydrocarbon receptor-interacting protein regulates tumorigenic and metastatic properties of colorectal cancer cells driving liver metastasis.
Solís-Fernández G, Montero-Calle A, Sánchez-Martínez M, Peláez-García A, Fernández-Aceñero MJ, Pallarés P, Alonso-Navarro M, Mendiola M, Hendrix J, Hardisson D, Bartolomé RA, Hofkens J, Rocha S, Barderas R
British journal of cancer 2022 Jun;126(11):1604-1615
British journal of cancer 2022 Jun;126(11):1604-1615
Atractyloside-A ameliorates spleen deficiency diarrhea by interfering with TLR4/MyD88/NF-κB signaling activation and regulating intestinal flora homeostasis.
Xu J, Liu C, Shi K, Sun X, Song C, Xu K, Liu Y
International immunopharmacology 2022 Jun;107:108679
International immunopharmacology 2022 Jun;107:108679
Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy.
Zhao Y, Zhang H, Zhang SL, Wei J, Zheng LL, Du JK, Zhu XY, Jiang L, Liu YJ
Annals of translational medicine 2022 Jun;10(11):630
Annals of translational medicine 2022 Jun;10(11):630
Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets.
Tian S, Wang J, Gao R, Wang J, Zhu W
Journal of animal science and biotechnology 2022 Jun 3;13(1):70
Journal of animal science and biotechnology 2022 Jun 3;13(1):70
Longitudinal 16S rRNA Sequencing Reveals Relationships among Alterations of Gut Microbiota and Nonalcoholic Fatty Liver Disease Progression in Mice.
Zhuge A, Li S, Lou P, Wu W, Wang K, Yuan Y, Xia J, Li B, Li L
Microbiology spectrum 2022 Jun 29;10(3):e0004722
Microbiology spectrum 2022 Jun 29;10(3):e0004722
Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia.
Wu DM, He M, Zhao YY, Deng SH, Liu T, Zhang T, Zhang F, Wang YY, Xu Y
Cell communication and signaling : CCS 2022 Jun 27;20(1):98
Cell communication and signaling : CCS 2022 Jun 27;20(1):98
Periodontitis may induce gut microbiota dysbiosis via salivary microbiota.
Bao J, Li L, Zhang Y, Wang M, Chen F, Ge S, Chen B, Yan F
International journal of oral science 2022 Jun 23;14(1):32
International journal of oral science 2022 Jun 23;14(1):32
Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.
Huang T, Che Q, Chen X, Chen D, Yu B, He J, Chen H, Yan H, Zheng P, Luo Y, Huang Z
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7576-7585
Journal of agricultural and food chemistry 2022 Jun 22;70(24):7576-7585
Analysis by transcriptomics and metabolomics for the proliferation inhibition and dysfunction through redox imbalance-mediated DNA damage response and ferroptosis in male reproduction of mice and TM4 Sertoli cells exposed to PM(2.5).
Shi F, Zhang Z, Cui H, Wang J, Wang Y, Tang Y, Yang W, Zou P, Ling X, Han F, Liu J, Chen Q, Liu C, Cao J, Ao L
Ecotoxicology and environmental safety 2022 Jun 15;238:113569
Ecotoxicology and environmental safety 2022 Jun 15;238:113569
Oxidized PUFAs Increase Susceptibility of Mice to Salmonella Infection by Diminishing Host's Innate Immune Responses.
Wang Y, Liu J, Liu H, Liu L, Gao X, Tong Y, Song S, Yan C
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6407-6417
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6407-6417
Burn Injury-Induced Extracellular Vesicle Production and Characteristics.
Yang X, Chatterjee V, Zheng E, Reynolds A, Ma Y, Villalba N, Tran T, Jung M, Smith DJ, Wu MH, Yuan SY
Shock (Augusta, Ga.) 2022 Jun 1;57(6):228-242
Shock (Augusta, Ga.) 2022 Jun 1;57(6):228-242
Breast Cancer Stem Cells-derived Extracellular Vesicles Affect PPARG Expression by Delivering MicroRNA-197 in Breast Cancer Cells.
Li L, Xiong Y, Wang N, Zhu M, Gu Y
Clinical breast cancer 2022 Jul;22(5):478-490
Clinical breast cancer 2022 Jul;22(5):478-490
Lactobacillus plantarum ZY08 relieves chronic alcohol-induced hepatic steatosis and liver injury in mice via restoring intestinal flora homeostasis.
Ding Q, Cao F, Lai S, Zhuge H, Chang K, Valencak TG, Liu J, Li S, Ren D
Food research international (Ottawa, Ont.) 2022 Jul;157:111259
Food research international (Ottawa, Ont.) 2022 Jul;157:111259
Protective role of casuarinin from Melastoma malabathricum against a mouse model of 5-fluorouracil-induced intestinal mucositis: Impact on inflammation and gut microbiota dysbiosis.
Chen KJ, Huang YL, Kuo LM, Chen YT, Hung CF, Hsieh PW
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154092
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154092
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Yu T, Liu Y, Xue J, Sun X, Zhu D, Ma L, Guo Y, Jin T, Cao H, Chen Y, Zhu T, Li X, Liang H, Du Z, Shan H
Cell death discovery 2022 Jul 9;8(1):312
Cell death discovery 2022 Jul 9;8(1):312
LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia.
Zhao C, Liu Y, Meng J, Wang X, Liu X, Li W, Zhou Q, Xiang J, Li N, Hou S
Investigative ophthalmology & visual science 2022 Jul 8;63(8):25
Investigative ophthalmology & visual science 2022 Jul 8;63(8):25
Human 2D Crypt Model for Assaying Intestinal Stem Cell Proliferation and Differentiation.
Wang Y, Sims CE, Allbritton NL
Analytical chemistry 2022 Jul 5;94(26):9345-9354
Analytical chemistry 2022 Jul 5;94(26):9345-9354
Neuroprotective Effects of Chlorogenic Acid in a Mouse Model of Intracerebral Hemorrhage Associated with Reduced Extracellular Matrix Metalloproteinase Inducer.
Liu Y, Wang F, Li Z, Mu Y, Yong VW, Xue M
Biomolecules 2022 Jul 22;12(8)
Biomolecules 2022 Jul 22;12(8)
Chitosan Oligosaccharide Attenuates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction through Suppressing the Inflammatory Response and Oxidative Stress in Mice.
Tao W, Wang G, Pei X, Sun W, Wang M
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 17;11(7)
Delayed administration of nafamostat mesylate inhibits thrombin-mediated blood-spinal cord barrier breakdown during acute spinal cord injury in rats.
Zhao C, Zhou T, Zhao X, Pang Y, Li W, Fan B, Li M, Liu X, Ma L, Zhang J, Sun C, Shen W, Kong X, Yao X, Feng S
Journal of neuroinflammation 2022 Jul 16;19(1):189
Journal of neuroinflammation 2022 Jul 16;19(1):189
Effect of Houpo-Mahuang Decoction on aggravated asthma induced by cigarette smoke and the expression of TRPA1 and tight junctions in mice.
Sun YB, Ni Y, Fan XS, Zhou LP, Yue QF, Shang EX
Journal of ethnopharmacology 2022 Jul 15;293:115217
Journal of ethnopharmacology 2022 Jul 15;293:115217
Metformin protects against pericyte apoptosis and promotes neurogenesis through suppressing JNK p38 MAPK signalling activation in ischemia/reperfusion injury.
Liu C, Zhang D, Lu Z, Man J, Zhang Z, Fu X, Cui K, Wang J
Neuroscience letters 2022 Jul 13;783:136708
Neuroscience letters 2022 Jul 13;783:136708
Bryodulcosigenin a natural cucurbitane-type triterpenoid attenuates dextran sulfate sodium (DSS)-induced colitis in mice.
Li R, Chen C, Liu B, Shi W, Shimizu K, Zhang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153814
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;94:153814
Radiocontrast agent and intraductal pressure promote the progression of post-ERCP pancreatitis by regulating inflammatory response, cellular apoptosis, and tight junction integrity.
Zhang D, Man X, Li L, Tang J, Liu F
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Jan;22(1):74-82
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2022 Jan;22(1):74-82
A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury.
Wu C, Du M, Yu R, Cheng Y, Wu B, Fu J, Tan W, Zhou Q, Balawi E, Liao ZB
Free radical biology & medicine 2022 Jan;178:271-294
Free radical biology & medicine 2022 Jan;178:271-294
Enterococcus faecium HDRsEf1 inhibits Lipopolysaccharide-induced downregulation of zona occludens -1 expression via toll-like receptor 2/4-mediated c-Jun N-terminal kinase/activator protein-1 signalling pathways.
Liu L, Li Y, He Y, Wang Z, Zhao H, Jin X, Shi D, Wang X
Journal of applied microbiology 2022 Jan;132(1):605-617
Journal of applied microbiology 2022 Jan;132(1):605-617
Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis.
Li H, Zhang Y, Liu M, Fan C, Feng C, Lu Q, Xiang C, Lu H, Yang X, Wu B, Zou D, Tang W
Acta pharmaceutica Sinica. B 2022 Jan;12(1):228-245
Acta pharmaceutica Sinica. B 2022 Jan;12(1):228-245
Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours.
Yu X, Bai Y, Han B, Ju M, Tang T, Shen L, Li M, Yang L, Zhang Z, Hu G, Chao J, Zhang Y, Yao H
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Journal of extracellular vesicles 2022 Jan;11(1):e12185
Apple polyphenols improve intestinal barrier function by enhancing antioxidant capacity and suppressing inflammation in weaning piglets.
Guo Z, Chen X, Huang Z, Chen D, Yu J, Yan H, Chen H, He J, Zheng P, Luo Y, Yu B
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13747
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13747
Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue.
Song X, Yu Y, Leng Y, Ma L, Mu J, Wang Z, Xu Y, Zhu H, Qiu X, Li P, Li J, Wang D
Journal of tissue engineering 2022 Jan-Dec;13:20417314221125310
Journal of tissue engineering 2022 Jan-Dec;13:20417314221125310
Immunomodulatory Effect of Serum Exosomes From Crohn Disease on Macrophages via Let-7b-5p/TLR4 Signaling.
Gong L, Xiao J, Yi J, Xiao J, Lu F, Liu X
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
Inflammatory bowel diseases 2022 Jan 5;28(1):96-108
Online Measurement System for Dynamic Flow Bioreactors to Study Barrier Integrity of hiPSC-Based Blood-Brain Barrier In Vitro Models.
Choi J, Mathew S, Oerter S, Appelt-Menzel A, Hansmann J, Schmitz T
Bioengineering (Basel, Switzerland) 2022 Jan 16;9(1)
Bioengineering (Basel, Switzerland) 2022 Jan 16;9(1)
De novo Lipogenesis in Astrocytes Promotes the Repair of Blood-Brain Barrier after Transient Cerebral Ischemia Through Interleukin-33.
Wei H, Zhen L, Wang S, Zhang Y, Wang K, Jia P, Zhang Y, Wu Z, Yang Q, Hou W, Lv J, Zhang P
Neuroscience 2022 Jan 15;481:85-98
Neuroscience 2022 Jan 15;481:85-98
Protective effects of polysaccharides from Atractylodes macrocephalae Koidz. against dextran sulfate sodium induced intestinal mucosal injury on mice.
Kai L, Zong X, Jiang Q, Lu Z, Wang F, Wang Y, Wang T, Jin M
International journal of biological macromolecules 2022 Jan 15;195:142-151
International journal of biological macromolecules 2022 Jan 15;195:142-151
Identifying distinct oxygen diffusivity through type I pneumocyte-like cell layers using microfluidic device.
Tung YC, Wang CK, Huang YK, Huang CK, Peng CC, Patra B, Chen HK, Tsao PN, Ling TY
Talanta 2022 Jan 1;236:122882
Talanta 2022 Jan 1;236:122882
Cordycepin, a major bioactive component of Cordyceps militaris, ameliorates diabetes-induced testicular damage through the Sirt1/Foxo3a pathway.
Huang T, Zhou Y, Lu X, Tang C, Ren C, Bao X, Deng Z, Cao X, Zou J, Zhang Q, Ma B
Andrologia 2022 Feb;54(1):e14294
Andrologia 2022 Feb;54(1):e14294
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2022 Feb;41(6):770-781
Oncogene 2022 Feb;41(6):770-781
Oral delivery of decanoic acid conjugated plant protein shell incorporating hybrid nanosystem leverage intestinal absorption of polyphenols.
Miao R, Jin F, Wang Z, Lu W, Liu J, Li X, Zhang RX
Biomaterials 2022 Feb;281:121373
Biomaterials 2022 Feb;281:121373
MicroRNA-582-5p regulates cell invasion in bladder cancer through targeting Forkhead Box G1.
Zhuang J, Hao J, Bu F, Yin H, Chen W, Guo H
Pathology, research and practice 2022 Feb;230:153752
Pathology, research and practice 2022 Feb;230:153752
Hyperglycemia induces corneal endothelial dysfunction through attenuating mitophagy.
Chen C, Zhou Q, Li Z, Duan H, Liu Y, Wan L, Wang H, Xie L
Experimental eye research 2022 Feb;215:108903
Experimental eye research 2022 Feb;215:108903
Connexin32 ameliorates epithelial-to-mesenchymal-transition in diabetic renal tubular via inhibiting NOX4.
Sun X, Xiao H, Li S, Chen R, Lin Z, Yang Y, Chen Z, Deng L, Huang H
Pharmacological research 2022 Feb;176:106084
Pharmacological research 2022 Feb;176:106084
CRH/CRHR1 modulates cerebrovascular endothelial cell permeability in association with S1PR2 and S1PR3 under oxidative stress.
Mu J, Que Y, Li X, Zhou F, Jin L, Li S, Zhu C
Vascular pharmacology 2022 Feb;142:106941
Vascular pharmacology 2022 Feb;142:106941
Hydroxytyrosol Alleviates Dextran Sulfate Sodium-Induced Colitis by Modulating Inflammatory Responses, Intestinal Barrier, and Microbiome.
Wang Q, Wang C, Abdullah, Tian W, Qiu Z, Song M, Cao Y, Xiao J
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2241-2252
Effects of Exopolysaccharides from Lactiplantibacillus plantarum JLAU103 on Intestinal Immune Response, Oxidative Stress, and Microbial Communities in Cyclophosphamide-Induced Immunosuppressed Mice.
Wang J, Li M, Gao Y, Li H, Fang L, Liu C, Liu X, Min W
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2197-2210
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2197-2210
Akkermansia muciniphila Ameliorates Acetaminophen-Induced Liver Injury by Regulating Gut Microbial Composition and Metabolism.
Xia J, Lv L, Liu B, Wang S, Zhang S, Wu Z, Yang L, Bian X, Wang Q, Wang K, Zhuge A, Li S, Yan R, Jiang H, Xu K, Li L
Microbiology spectrum 2022 Feb 23;10(1):e0159621
Microbiology spectrum 2022 Feb 23;10(1):e0159621
LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland.
Ma R, Gong D, You H, Xu C, Lu Y, Bergers G, Werb Z, Klein OD, Petritsch CK, Lu P
Cell reports 2022 Feb 15;38(7):110375
Cell reports 2022 Feb 15;38(7):110375
LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice.
Wang S, Qian Z, Ge X, Li C, Xue M, Liang K, Ma R, Ouyang L, Zheng L, Jing J, Cao S, Zhang Y, Yang Y, Chen Y, Ma J, Yao B
Cellular and molecular life sciences : CMLS 2022 Feb 1;79(2):114
Cellular and molecular life sciences : CMLS 2022 Feb 1;79(2):114
A Pilot Application of an iTRAQ-Based Proteomics Screen Estimates the Effects of Cigarette Smokers' Serum on RPE Cells With AMD High-Risk Alleles.
Cai B, Zhang Z, Sun S, Lin T, Ke Y, Li Z, Yang J, Li X
Translational vision science & technology 2022 Feb 1;11(2):15
Translational vision science & technology 2022 Feb 1;11(2):15
Effects of dietary dihydromyricetin supplementation on intestinal barrier and humoral immunity in growing-finishing pigs.
Wei C, Chen X, Chen D, He J, Zheng P, Chen H, Yan H, Yu B, Luo Y, Huang Z
Animal biotechnology 2022 Dec;33(7):1398-1406
Animal biotechnology 2022 Dec;33(7):1398-1406
Hesperidin partly ameliorates the decabromodiphenyl ether-induced reproductive toxicity in pubertal mice.
Li S, Che S, Chen S, Ruan Z, Zhang L
Environmental science and pollution research international 2022 Dec;29(60):90391-90403
Environmental science and pollution research international 2022 Dec;29(60):90391-90403
Acteoside alleviates dextran sulphate sodium‑induced ulcerative colitis via regulation of the HO‑1/HMGB1 signaling pathway.
Guo W, Wang X, Liu F, Chen S, Wang S, Zhang Q, Yuan L, Du S
Molecular medicine reports 2022 Dec;26(6)
Molecular medicine reports 2022 Dec;26(6)
Polysaccharide ORP-1 isolated from Oudemansiella raphanipes ameliorates age-associated intestinal epithelial barrier dysfunction in Caco-2 cells monolayer.
Pan WJ, Shi LL, Ren YR, Yao CY, Lu YM, Chen Y
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt A):112038
Food research international (Ottawa, Ont.) 2022 Dec;162(Pt A):112038
Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiation.
Xia S, Chen L, Li Z, Li Y, Zhou Y, Sun S, Su Y, Xu X, Shao J, Zhang Z, Kong D, Zhang F, Zheng S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154460
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154460
Dahuang Mudan decoction repairs intestinal barrier in chronic colitic mice by regulating the function of ILC3.
Huang S, Wang X, Xie X, Su Y, Pan Z, Li Y, Liang J, Zhang M, Pan S, Xu B, Li L, Chen J, Luo X, Zhou L
Journal of ethnopharmacology 2022 Dec 5;299:115652
Journal of ethnopharmacology 2022 Dec 5;299:115652
Glutathione Protects against Paraquat-Induced Oxidative Stress by Regulating Intestinal Barrier, Antioxidant Capacity, and CAR Signaling Pathway in Weaned Piglets.
Xiang X, Wang H, Zhou W, Wang C, Guan P, Xu G, Zhao Q, He L, Yin Y, Li T
Nutrients 2022 Dec 30;15(1)
Nutrients 2022 Dec 30;15(1)
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Yan J, Zhang Y, Wang L, Li Z, Tang S, Wang Y, Gu N, Sun X, Li L
Journal of neuroinflammation 2022 Dec 3;19(1):289
Journal of neuroinflammation 2022 Dec 3;19(1):289
A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors.
Sun Y, Li H, Liu L, Bai X, Wu L, Shan J, Sun X, Wang Q, Guo Y
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
Pharmaceuticals (Basel, Switzerland) 2022 Dec 29;16(1)
Effect of ginsenoside compound K on alleviating colitis via modulating gut microbiota.
Wang L, Shao L, Chen MY, Wang L, Zhang W, Tan FB, Huang WH
Chinese medicine 2022 Dec 28;17(1):146
Chinese medicine 2022 Dec 28;17(1):146
Integrated Profiles of Transcriptome and mRNA m6A Modification Reveal the Intestinal Cytotoxicity of Aflatoxin B1 on HCT116 Cells.
Wu Y, Bao W, Ren J, Li C, Chen M, Zhang D, Zhu A
Genes 2022 Dec 27;14(1)
Genes 2022 Dec 27;14(1)
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo.
Xia X, Lin H, Luo F, Wu X, Zhu L, Chen S, Luo H, Ye F, Peng X, Zhang Y, Yang G, Lin Q
Journal of agricultural and food chemistry 2022 Dec 21;70(50):15747-15762
Journal of agricultural and food chemistry 2022 Dec 21;70(50):15747-15762
Transcriptome and Gut Microbiota Profiling Analysis of ANIT-Induced Cholestasis and the Effects of Da-Huang-Xiao-Shi Decoction Intervention.
Wang W, Jiang S, Xu C, Tang L, Liang Y, Zhao Y, Zhu G
Microbiology spectrum 2022 Dec 21;10(6):e0324222
Microbiology spectrum 2022 Dec 21;10(6):e0324222
Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury.
Huang B, Gui M, Ni Z, He Y, Zhao J, Peng J, Lin J
Microbiology spectrum 2022 Dec 21;10(6):e0167722
Microbiology spectrum 2022 Dec 21;10(6):e0167722
Exploration of the mechanisms underlying the beneficial effect of Luo Tong formula on retinal function in diabetic rats via the "gut microbiota-inflammation-retina" axis.
Di S, Yao C, Qiao L, Li X, Pang B, Lin J, Wang J, Li M, Tong X
Chinese medicine 2022 Dec 2;17(1):133
Chinese medicine 2022 Dec 2;17(1):133
Intermittent Fasting Alleviates Risk Markers in a Murine Model of Ulcerative Colitis by Modulating the Gut Microbiome and Metabolome.
Wu J, Man D, Shi D, Wu W, Wang S, Wang K, Li Y, Yang L, Bian X, Wang Q, Li L
Nutrients 2022 Dec 14;14(24)
Nutrients 2022 Dec 14;14(24)
The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response.
Chamseddine D, Mahmud SA, Westfall AK, Castoe TA, Berg RE, Pellegrino MW
Cell reports 2022 Dec 13;41(11):111789
Cell reports 2022 Dec 13;41(11):111789
Betaine supplementation alleviates dextran sulfate sodium-induced colitis via regulating the inflammatory response, enhancing the intestinal barrier, and altering gut microbiota.
Zhao N, Yang Y, Chen C, Jing T, Hu Y, Xu H, Wang S, He Y, Liu E, Cui J
Food & function 2022 Dec 13;13(24):12814-12826
Food & function 2022 Dec 13;13(24):12814-12826
Effects of chitosan oligosaccharides (COS) and FMT from COS-dosed mice on intestinal barrier function and cell apoptosis.
Na K, Wei J, Zhang L, Fang Y, Li X, Lu S, Guo X
Carbohydrate polymers 2022 Dec 1;297:120043
Carbohydrate polymers 2022 Dec 1;297:120043
Microglia Regulate Blood-Brain Barrier Integrity via MiR-126a-5p/MMP9 Axis during Inflammatory Demyelination.
Yu Z, Fang X, Liu W, Sun R, Zhou J, Pu Y, Zhao M, Sun D, Xiang Z, Liu P, Ding Y, Cao L, He C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105442
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105442
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Hou Z, Ding Q, Li Y, Zhao Z, Yan F, Li Y, Wang X, Xu J, Chen W, Wu G, Ruan X, Zhao L
EBioMedicine 2022 Aug;82:104181
EBioMedicine 2022 Aug;82:104181
Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis.
Luo Y, Zhang Y, Han X, Yuan Y, Zhou Y, Gao Y, Yu H, Zhang J, Shi Y, Duan Y, Zhao X, Yan S, Hao H, Dai C, Zhao S, Shi J, Li W, Zhang S, Xu W, Fang N, Gong Y, Li Y
EBioMedicine 2022 Aug;82:104087
EBioMedicine 2022 Aug;82:104087
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Ge X, He Z, Cao C, Xue T, Jing J, Ma R, Zhao W, Liu L, Jueraitetibaike K, Ma J, Feng Y, Qian Z, Zou Z, Chen L, Fu C, Song N, Yao B
Redox biology 2022 Aug;54:102380
Redox biology 2022 Aug;54:102380
Pyroptosis participates in PM(2.5)-induced air-blood barrier dysfunction.
Jia R, Wei M, Zhang X, Du R, Sun W, Wang L, Song L
Environmental science and pollution research international 2022 Aug;29(40):60987-60997
Environmental science and pollution research international 2022 Aug;29(40):60987-60997
Chitosan-modified Phellinus igniarius polysaccharide PLGA nanoparticles ameliorated inflammatory bowel disease.
Bai X, Feng Z, Peng S, Zhu T, Jiao L, Mao N, Gu P, Liu Z, Yang Y, Wang D
Biomaterials advances 2022 Aug;139:213002
Biomaterials advances 2022 Aug;139:213002
Comparative Effects of Allulose, Fructose, and Glucose on the Small Intestine.
Suzuki T, Sato Y, Kadoya S, Takahashi T, Otomo M, Kobayashi H, Aoki K, Kantake M, Sugiyama M, Ferraris RP
Nutrients 2022 Aug 7;14(15)
Nutrients 2022 Aug 7;14(15)
Tollip Orchestrates Macrophage Polarization to Alleviate Intestinal Mucosal Inflammation.
Liu X, Ren X, Zhou L, Liu K, Deng L, Qing Q, Li J, Zhi F, Li M
Journal of Crohn's & colitis 2022 Aug 4;16(7):1151-1167
Journal of Crohn's & colitis 2022 Aug 4;16(7):1151-1167
Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.
Liu Z, Jiang Z, Zhang Z, Liu T, Fan Y, Liu T, Peng N
Microbiology spectrum 2022 Aug 31;10(4):e0064122
Microbiology spectrum 2022 Aug 31;10(4):e0064122
Protective effect of surface-layer proteins from four Lactobacillus strains on tumor necrosis factor-α-induced intestinal barrier dysfunction.
Zhang J, Li Q, Wu L, Xu S, Lu R
Journal of the science of food and agriculture 2022 Aug 30;102(11):4446-4453
Journal of the science of food and agriculture 2022 Aug 30;102(11):4446-4453
Neohesperidin Dihydrochalcone Ameliorates High-Fat Diet-Induced Glycolipid Metabolism Disorder in Rats.
Xiao Y, Su D, Hu X, Yang G, Shan Y
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9421-9431
Journal of agricultural and food chemistry 2022 Aug 3;70(30):9421-9431
Wumei pills attenuates 5-fluorouracil-induced intestinal mucositis through Toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-κB pathway and microbiota regulation.
Lu DX, Liu F, Wu H, Liu HX, Chen BY, Yan J, Lu Y, Sun ZG
World journal of gastroenterology 2022 Aug 28;28(32):4574-4599
World journal of gastroenterology 2022 Aug 28;28(32):4574-4599
Stigmasterol attenuates hepatic steatosis in rats by strengthening the intestinal barrier and improving bile acid metabolism.
Zhang Y, Gu Y, Jiang J, Cui X, Cheng S, Liu L, Huang Z, Liao R, Zhao P, Yu J, Wang J, Jia Y, Jin W, Zhou F
NPJ science of food 2022 Aug 27;6(1):38
NPJ science of food 2022 Aug 27;6(1):38
Psychological stress induces depressive-like behavior associated with bone marrow-derived monocyte infiltration into the hippocampus independent of blood-brain barrier disruption.
Hu H, Yang X, He Y, Duan C, Sun N
Journal of neuroinflammation 2022 Aug 24;19(1):208
Journal of neuroinflammation 2022 Aug 24;19(1):208
[Diethylhexyl phthalate induces anxiety-like behavior and learning and memory impairment in mice probably by damaging blood-brain barrier].
Li F, Zhu Y, Sun X, Hu H, Zhou M, Bai Y, Hu H
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 Aug 20;42(8):1237-1243
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 Aug 20;42(8):1237-1243
Ascorbic acid induces salivary gland function through TET2/acetylcholine receptor signaling in aging SAMP1/Klotho (-/-) mice.
Toan NK, Kim SA, Ahn SG
Aging 2022 Aug 11;14(15):6028-6046
Aging 2022 Aug 11;14(15):6028-6046
Urolithin A attenuates arsenic-induced gut barrier dysfunction.
Ghosh S, Banerjee M, Haribabu B, Jala VR
Archives of toxicology 2022 Apr;96(4):987-1007
Archives of toxicology 2022 Apr;96(4):987-1007
Curcumin Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice Through Regulating Gut Microbiota.
Guo X, Xu Y, Geng R, Qiu J, He X
Molecular nutrition & food research 2022 Apr;66(8):e2100943
Molecular nutrition & food research 2022 Apr;66(8):e2100943
Diosmetin has therapeutic efficacy in colitis regulating gut microbiota, inflammation, and oxidative stress via the circ-Sirt1/Sirt1 axis.
Li HL, Wei YY, Li XH, Zhang SS, Zhang RT, Li JH, Ma BW, Shao SB, Lv ZW, Ruan H, Zhou HG, Yang C
Acta pharmacologica Sinica 2022 Apr;43(4):919-932
Acta pharmacologica Sinica 2022 Apr;43(4):919-932
Dietary ferulic acid supplementation improves intestinal antioxidant capacity and intestinal barrier function in weaned piglets.
Chen X, Wang Y, Chen D, Yu B, Huang Z
Animal biotechnology 2022 Apr;33(2):356-361
Animal biotechnology 2022 Apr;33(2):356-361
Mesencephalic astrocyte-derived neurotrophic factor restores blood-brain barrier integrity of aged mice after ischaemic stroke/reperfusion through anti-inflammation via TLR4/MyD88/NF-κB pathway.
Han D, Li F, Zhang H, Ji C, Shu Q, Wang C, Ni H, Zhu Y, Wang S
Journal of drug targeting 2022 Apr;30(4):430-441
Journal of drug targeting 2022 Apr;30(4):430-441
Gelsolin impairs barrier function in pancreatic ductal epithelial cells by actin filament depolymerization in hypertriglyceridemia-induced pancreatitis in vitro.
Yang HY, Liang ZH, Xie JL, Wu Q, Qin YY, Zhang SY, Tang GD
Experimental and therapeutic medicine 2022 Apr;23(4):290
Experimental and therapeutic medicine 2022 Apr;23(4):290
Interfering with alternatively activated macrophages by CSF-1R inhibition exerts therapeutic capacity on allergic airway inflammation.
Xiang C, Fan C, Lu Q, Liu M, Lu H, Feng C, Wu Y, Wu B, Li H, Tang W
Biochemical pharmacology 2022 Apr;198:114952
Biochemical pharmacology 2022 Apr;198:114952
Tetrastigma hemsleyanum Diels et Gilg ameliorates lipopolysaccharide induced sepsis via repairing the intestinal mucosal barrier.
Zhan L, Pu J, Zheng J, Hang S, Pang L, Dai M, Ji C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Apr;148:112741
Late-onset hearing loss case associated with a heterozygous truncating variant of DIAPH1.
Kim BJ, Miyoshi T, Chaudhry T, Friedman TB, Choi BY, Ueyama T
Clinical genetics 2022 Apr;101(4):466-471
Clinical genetics 2022 Apr;101(4):466-471
Industrially Produced Rice Protein Ameliorates Dextran Sulfate Sodium-Induced Colitis via Protecting the Intestinal Barrier, Mitigating Oxidative Stress, and Regulating Gut Microbiota.
Huang Z, Yang W, Wang X, Guo F, Cheng Y, Cao L, Zhu W, Sun Y, Xiong H
Journal of agricultural and food chemistry 2022 Apr 27;70(16):4952-4965
Journal of agricultural and food chemistry 2022 Apr 27;70(16):4952-4965
Anemone chinensis Bunge aqueous enema alleviates dextran sulfate sodium-induced colitis via inhibition of inflammation and regulation of the colonic mucosal microbiota.
Dong L, Fan X, Li Q, Li J, Chen G, Yang D, Li Y, Zhao L, Yin H, Wang X, Liu X, Zhao Z, Lin S
Journal of ethnopharmacology 2022 Apr 24;288:114916
Journal of ethnopharmacology 2022 Apr 24;288:114916
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Song L, Wu T, Zhang L, Wan J, Ruan Z
Food & function 2022 Apr 20;13(8):4562-4575
Food & function 2022 Apr 20;13(8):4562-4575
Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.
Yan S, Chen J, Zhu L, Guo T, Qin D, Hu Z, Han S, Wang J, Matias FB, Wen L, Luo F, Lin Q
Food & function 2022 Apr 20;13(8):4486-4501
Food & function 2022 Apr 20;13(8):4486-4501
Comparison of the effects of different calorie amounts of enteral nutrition in hypercatabolism associated with ghrelin-POMC in endotoxemic rats.
Duan J, Cheng M, Xu Y, Tang S, Li X, Chen Y, Lu H, Gao T, Yu W
Nutrition & metabolism 2022 Apr 15;19(1):28
Nutrition & metabolism 2022 Apr 15;19(1):28
Sertoli cell and spermatogonial development in pigs.
Zheng Y, Gao Q, Li T, Liu R, Cheng Z, Guo M, Xiao J, Wu D, Zeng W
Journal of animal science and biotechnology 2022 Apr 11;13(1):45
Journal of animal science and biotechnology 2022 Apr 11;13(1):45
Ubiquitin-Specific Protease 25 Aggravates Acute Pancreatitis and Acute Pancreatitis-Related Multiple Organ Injury by Destroying Tight Junctions Through Activation of The STAT3 Pathway.
Liu Z, Qi M, Tian S, Yang Q, Liu J, Wang S, Ji M, Yu R, Zeng S, Li J, Wei Y, Dong W
Frontiers in cell and developmental biology 2021;9:806850
Frontiers in cell and developmental biology 2021;9:806850
Cathelicidin-WA Protects Against LPS-Induced Gut Damage Through Enhancing Survival and Function of Intestinal Stem Cells.
Wang S, Kai L, Zhu L, Xu B, Chen N, Valencak TG, Wang Y, Shan T
Frontiers in cell and developmental biology 2021;9:685363
Frontiers in cell and developmental biology 2021;9:685363
P16 (I NK 4a) Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 Deficiency.
Zhou J, Hou C, Chen H, Qin Z, Miao Z, Zhao J, Wang Q, Cui M, Xie C, Wang R, Li Q, Zuo G, Miao D, Jin J
Frontiers in cell and developmental biology 2021;9:671564
Frontiers in cell and developmental biology 2021;9:671564
Electroacupuncture Reduces Oocyte Number and Maintains Vascular Barrier Against Ovarian Hyperstimulation Syndrome by Regulating CD200.
Chen L, Huang X, Wang L, Wang C, Tang X, Gu M, Jing J, Ma R, Ge X, Yao B
Frontiers in cell and developmental biology 2021;9:648578
Frontiers in cell and developmental biology 2021;9:648578
Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice.
Li Y, Tao Y, Xu J, He Y, Zhang W, Jiang Z, He Y, Liu H, Chen M, Zhang W, Xing Z
Frontiers in medicine 2021;8:732039
Frontiers in medicine 2021;8:732039
Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model.
Gu L, Ren F, Fang X, Yuan L, Liu G, Wang S
Frontiers in medicine 2021;8:660614
Frontiers in medicine 2021;8:660614
Bovine Lactoferrin Protects Dextran Sulfate Sodium Salt Mice Against Inflammation and Impairment of Colonic Epithelial Barrier by Regulating Gut Microbial Structure and Metabolites.
Wang S, Zhou J, Xiao D, Shu G, Gu L
Frontiers in nutrition 2021;8:660598
Frontiers in nutrition 2021;8:660598
Effects of Guava (Psidium guajava L.) Leaf Extract on the Metabolomics of Serum and Feces in Weaned Piglets Challenged by Escherichia coli.
Wang D, Zhou L, Zhou H, Hou G
Frontiers in veterinary science 2021;8:656179
Frontiers in veterinary science 2021;8:656179
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
Heme Oxygenase-1-Modified Bone Marrow Mesenchymal Stem Cells Combined with Normothermic Machine Perfusion Repairs Bile Duct Injury in a Rat Model of DCD Liver Transplantation via Activation of Peribiliary Glands through the Wnt Pathway.
Tian X, Cao H, Wu L, Zheng W, Yuan M, Li X, Song H, Shen Z
Stem cells international 2021;2021:9935370
Stem cells international 2021;2021:9935370
Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota.
Zhou X, Lu J, Wei K, Wei J, Tian P, Yue M, Wang Y, Hong D, Li F, Wang B, Chen T, Fang X
Oxidative medicine and cellular longevity 2021;2021:9424582
Oxidative medicine and cellular longevity 2021;2021:9424582
Targeting the Ang2/Tie2 Axis with Tanshinone IIA Elicits Vascular Normalization in Ischemic Injury and Colon Cancer.
Zou W, Qian C, Zhang S, Wan X, Wei Z, Li X, Wu Y, Chen W, Wang A, Zhao Y, Lu Y
Oxidative medicine and cellular longevity 2021;2021:7037786
Oxidative medicine and cellular longevity 2021;2021:7037786
HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1(-/-) Mice.
Zhang Z, Zhang L, Zhang Q, Liu B, Li F, Xin Y, Duan Z
Oxidative medicine and cellular longevity 2021;2021:6620873
Oxidative medicine and cellular longevity 2021;2021:6620873
BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage.
Wan Y, Song M, Xie X, Chen Z, Gao Z, Wu X, Huang R, Chen M
Mediators of inflammation 2021;2021:5522291
Mediators of inflammation 2021;2021:5522291
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Yang W, Xu X, Xu M, Zhou J, Xi Z, Guo H, Ming J, Huang T
OncoTargets and therapy 2021;14:2339-2348
OncoTargets and therapy 2021;14:2339-2348
Overexpression of 15-Hydroxyprostaglandin Dehydrogenase Inhibits A549 Lung Adenocarcinoma Cell Growth via Inducing Cell Cycle Arrest and Inhibiting Epithelial-Mesenchymal Transition.
Wang W, Yang C, Deng H
Cancer management and research 2021;13:8887-8900
Cancer management and research 2021;13:8887-8900
Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.
Li T, Tang Z, Li C, Liu X, Cheng L, Yang Z, Zhu X, Liu W, Huang Y
Frontiers in pharmacology 2021;12:804615
Frontiers in pharmacology 2021;12:804615
Evaluation of the Anti-Aging Effects of a Probiotic Combination Isolated From Centenarians in a SAMP8 Mouse Model.
Fang X, Yue M, Wei J, Wang Y, Hong D, Wang B, Zhou X, Chen T
Frontiers in immunology 2021;12:792746
Frontiers in immunology 2021;12:792746
Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury.
Gong S, Ma H, Zheng F, Huang J, Zhang Y, Yu B, Li F, Kou J
Frontiers in pharmacology 2021;12:777680
Frontiers in pharmacology 2021;12:777680
Integrated Analysis of the Cecal Microbiome and Plasma Metabolomics to Explore NaoMaiTong and Its Potential Role in Changing the Intestinal Flora and Their Metabolites in Ischemic Stroke.
Lin H, Chen S, Shen L, Hu T, Cai J, Zhan S, Liang J, Huang M, Xian M, Wang S
Frontiers in pharmacology 2021;12:773722
Frontiers in pharmacology 2021;12:773722
Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma.
Qiao Y, Chen Y, Tan C, Sun X, Chen X, Chen J
Frontiers in genetics 2021;12:764509
Frontiers in genetics 2021;12:764509
Inhibitor of Differentiation-2 Protein Ameliorates DSS-Induced Ulcerative Colitis by Inhibiting NF-κB Activation in Neutrophils.
Ren J, Yan D, Wang Y, Zhang J, Li M, Xiong W, Jing X, Li P, Zhao W, Xiong X, Wu M, Zhong G
Frontiers in immunology 2021;12:760999
Frontiers in immunology 2021;12:760999
The Panda-Derived Lactobacillus plantarum G201683 Alleviates the Inflammatory Response in DSS-Induced Panda Microbiota-Associated Mice.
Zhou Y, Duan L, Zeng Y, Niu L, Pu Y, Jacobs JP, Chang C, Wang J, Khalique A, Pan K, Fang J, Jing B, Zeng D, Ni X
Frontiers in immunology 2021;12:747045
Frontiers in immunology 2021;12:747045
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1.
Shi A, Li T, Zheng Y, Song Y, Wang H, Wang N, Dong L, Shi H
Frontiers in pharmacology 2021;12:693048
Frontiers in pharmacology 2021;12:693048
Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis.
Qu Y, Li X, Xu F, Zhao S, Wu X, Wang Y, Xie J
Frontiers in immunology 2021;12:679897
Frontiers in immunology 2021;12:679897
α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.
He Y, Chen J, Zhang Q, Zhang J, Wang L, Chen X, Molenaar AJ, Sun X
Frontiers in plant science 2021;12:673774
Frontiers in plant science 2021;12:673774
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Ye R, Wang C, Sun P, Bai S, Zhao L
Frontiers in pharmacology 2021;12:669403
Frontiers in pharmacology 2021;12:669403
Introduction of Colonic and Fecal Microbiota From an Adult Pig Differently Affects the Growth, Gut Health, Intestinal Microbiota and Blood Metabolome of Newborn Piglets.
Qi R, Zhang Z, Wang J, Qiu X, Wang Q, Yang F, Huang J, Liu Z
Frontiers in microbiology 2021;12:623673
Frontiers in microbiology 2021;12:623673
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
Chen L, Zhong X, Cao W, Mao M, Li W, Yang H, Li M, Shi M, Zhang Y, Deng Y, Zu X, Liu J
Frontiers in immunology 2021;12:609319
Frontiers in immunology 2021;12:609319
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization.
Chen C, Yuan W, Zhou Q, Shao B, Guo Y, Wang W, Yang S, Guo Y, Zhao L, Dang Q, Yang X, Wang G, Kang Q, Ji Z, Liu J, Sun Z
Theranostics 2021;11(9):4298-4315
Theranostics 2021;11(9):4298-4315
Susceptibility of Human Airway Tissue Models Derived From Different Anatomical Sites to Bordetella pertussis and Its Virulence Factor Adenylate Cyclase Toxin.
Sivarajan R, Kessie DK, Oberwinkler H, Pallmann N, Walles T, Scherzad A, Hackenberg S, Steinke M
Frontiers in cellular and infection microbiology 2021;11:797491
Frontiers in cellular and infection microbiology 2021;11:797491
Intestinal Microbiota Play an Important Role in the Treatment of Type I Diabetes in Mice With BefA Protein.
Qin Q, Chen Y, Li Y, Wei J, Zhou X, Le F, Hu H, Chen T
Frontiers in cellular and infection microbiology 2021;11:719542
Frontiers in cellular and infection microbiology 2021;11:719542
Polydatin has anti-inflammatory and antioxidant effects in LPS-induced macrophages and improves DSS-induced mice colitis.
Chen G, Yang Z, Wen D, Guo J, Xiong Q, Li P, Zhao L, Wang J, Wu C, Dong L
Immunity, inflammation and disease 2021 Sep;9(3):959-970
Immunity, inflammation and disease 2021 Sep;9(3):959-970
Neutrophil extracellular traps induce thrombogenicity in severe carotid stenosis.
Zhang S, Guo M, Liu Q, Liu J, Cui Y
Immunity, inflammation and disease 2021 Sep;9(3):1025-1036
Immunity, inflammation and disease 2021 Sep;9(3):1025-1036
The important roles and molecular mechanisms of annexin A(2) autoantibody in children with nephrotic syndrome.
Ye Q, Zhang Y, Zhuang J, Bi Y, Xu H, Shen Q, Liu J, Fu H, Wang J, Feng C, Tang X, Liu F, Gu W, Zhao F, Zhang J, Qin Y, Shang S, Shen H, Chen X, Shen H, Liu A, Xia Y, Lu Z, Shu Q, Mao J
Annals of translational medicine 2021 Sep;9(18):1452
Annals of translational medicine 2021 Sep;9(18):1452
Enteromorpha polysaccharide-zinc replacing prophylactic antibiotics contributes to improving gut health of weaned piglets.
Xie C, Zhang Y, Niu K, Liang X, Wang H, Shan J, Wu X
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2021 Sep;7(3):641-649
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2021 Sep;7(3):641-649
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent.
Mondal A, Saha P, Bose D, Chatterjee S, Seth RK, Xiao S, Porter DE, Brooks BW, Scott GI, Nagarkatti M, Nagarkatti P, Chatterjee S
Toxicology 2021 Sep;461:152901
Toxicology 2021 Sep;461:152901
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Magnetically-propelled fecal surrogates for modeling the impact of solid-induced shear forces on primary colonic epithelial cells.
Hinman SS, Huling J, Wang Y, Wang H, Bretherton RC, DeForest CA, Allbritton NL
Biomaterials 2021 Sep;276:121059
Biomaterials 2021 Sep;276:121059
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Liu C, Cheng Y, Guo Y, Qian H
Brain research bulletin 2021 Sep;174:184-193
Brain research bulletin 2021 Sep;174:184-193
Mfsd2a overexpression alleviates vascular dysfunction in diabetic retinopathy.
Zhang CL, Wang HL, Li PC, Hong CD, Chen AQ, Qiu YM, Zeng AP, Zhou YF, Hu B, Li YN
Pharmacological research 2021 Sep;171:105755
Pharmacological research 2021 Sep;171:105755
Treatment of early brain injury after subarachnoid hemorrhage in the rat model by inhibiting p53-induced ferroptosis.
Kuang H, Wang T, Liu L, Tang C, Li T, Liu M, Wang T, Zhong W, Wang Y
Neuroscience letters 2021 Sep 25;762:136134
Neuroscience letters 2021 Sep 25;762:136134
Lactobacillus johnsonii L531 Alleviates the Damage Caused by Salmonella Typhimurium via Inhibiting TLR4, NF-κB, and NLRP3 Inflammasome Signaling Pathways.
Chen S, Li Y, Chu B, Yuan L, Liu N, Zhu Y, Wang J
Microorganisms 2021 Sep 17;9(9)
Microorganisms 2021 Sep 17;9(9)
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Hu S, Li S, Liu Y, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat.
Xun W, Fu Q, Shi L, Cao T, Jiang H, Ma Z
International immunopharmacology 2021 Oct;99:107989
International immunopharmacology 2021 Oct;99:107989
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa.
Zhong G, Zhang J, Guo Y, Wang Y, Wu M, Ren J, Li Y, Zhang X, Zhou B, Zhao W, Lou Y, Wang H, Ye J
International immunopharmacology 2021 Oct;99:107980
International immunopharmacology 2021 Oct;99:107980
Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure.
Lesko AC, Keller R, Chen P, Sutherland A
Developmental biology 2021 Oct;478:59-75
Developmental biology 2021 Oct;478:59-75
Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion.
Yu W, Jin H, Sun W, Nan D, Deng J, Jia J, Yu Z, Huang Y
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 Oct;41(10):2656-2675
AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke.
Xu SY, Bian HJ, Shu S, Xia SN, Gu Y, Zhang MJ, Xu Y, Cao X
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
CNS neuroscience & therapeutics 2021 Oct;27(10):1224-1237
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke.
Li L, Cheng SQ, Guo W, Cai ZY, Sun YQ, Huang XX, Yang J, Ji J, Chen YY, Dong YF, Cheng H, Sun XL
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Journal of cellular and molecular medicine 2021 Oct;25(20):9753-9766
Regulation of blood-brain barrier permeability by Salvinorin A via alleviating endoplasmic reticulum stress in brain endothelial cell after ischemia stroke.
Xin J, Ma X, Chen W, Zhou W, Dong H, Wang Z, Ji F
Neurochemistry international 2021 Oct;149:105093
Neurochemistry international 2021 Oct;149:105093
Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.
Chen G, Zeng H, Li X, Liu J, Li Z, Xu R, Ma Y, Liu C, Xue B
Cell death & disease 2021 Oct 30;12(11):1034
Cell death & disease 2021 Oct 30;12(11):1034
Improved epithelial cell-cell adhesion using molecular mobility of supramolecular surfaces.
Mikami R, Arisaka Y, Hakariya M, Iwata T, Yui N
Biomaterials science 2021 Oct 26;9(21):7151-7158
Biomaterials science 2021 Oct 26;9(21):7151-7158
Fructooligosaccharide supplementation alleviated the pathological immune response and prevented the impairment of intestinal barrier in DSS-induced acute colitis mice.
Liao M, Zhang Y, Qiu Y, Wu Z, Zhong Z, Zeng X, Zeng Y, Xiong L, Wen Y, Liu R
Food & function 2021 Oct 19;12(20):9844-9854
Food & function 2021 Oct 19;12(20):9844-9854
Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply.
Du K, Li S, Li C, Li P, Miao C, Luo T, Qiu B, Ding W
Acta biomaterialia 2021 Oct 15;134:228-239
Acta biomaterialia 2021 Oct 15;134:228-239
Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Lu Y, Hao R, Hu Y, Wei Y, Xie Y, Shen Y, Rui Q, Yu G
Chemico-biological interactions 2021 Oct 1;348:109653
Chemico-biological interactions 2021 Oct 1;348:109653
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
Lu YW, Hao RJ, Wei YY, Yu GR
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice.
Song M, Zhang S, Tao Z, Li J, Shi Y, Xiong Y, Zhang W, Liu C, Chen S
Biomaterials 2021 Nov;278:121183
Biomaterials 2021 Nov;278:121183
Selenium-enriched Bifidobacterium longum DD98 attenuates irinotecan-induced intestinal and hepatic toxicity in vitro and in vivo.
Zhu H, Lu C, Gao F, Qian Z, Yin Y, Kan S, Chen D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112192
Seaweed polysaccharide mitigates intestinal barrier dysfunction induced by enterotoxigenic Escherichia coli through NF-κB pathway suppression in porcine intestinal epithelial cells.
Guo X, Chen J, Yang J, He Q, Luo B, Lu Y, Zou T, Wang Z, You J
Journal of animal physiology and animal nutrition 2021 Nov;105(6):1063-1074
Journal of animal physiology and animal nutrition 2021 Nov;105(6):1063-1074
Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting the intestinal barrier, mitigating oxidative stress and regulating the gut microbiota.
Wu T, Wang X, Xiong H, Deng Z, Peng X, Xiao L, Jiang L, Sun Y
Food & function 2021 Nov 29;12(23):11760-11776
Food & function 2021 Nov 29;12(23):11760-11776
TBHQ attenuates ferroptosis against 5-fluorouracil-induced intestinal epithelial cell injury and intestinal mucositis via activation of Nrf2.
Deng S, Wu D, Li L, Li J, Xu Y
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Cellular & molecular biology letters 2021 Nov 18;26(1):48
Ripened Pu-Erh Tea Improved the Enterohepatic Circulation in a Circadian Rhythm Disorder Mice Model.
Hu S, Chen Y, Zhao S, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
Journal of agricultural and food chemistry 2021 Nov 17;69(45):13533-13545
(-)-Epigallocatechin-3-gallate mitigates cyclophosphamide-induced intestinal injury by modulating the tight junctions, inflammation and dysbiosis in mice.
Wei R, Liu X, Wang Y, Dong J, Wu F, Mackenzie GG, Su Z
Food & function 2021 Nov 15;12(22):11671-11685
Food & function 2021 Nov 15;12(22):11671-11685
Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation.
Guo F, Tsao R, Li C, Wang X, Zhang H, Jiang L, Sun Y, Xiong H
Foods (Basel, Switzerland) 2021 Nov 11;10(11)
Foods (Basel, Switzerland) 2021 Nov 11;10(11)
Neuroprotection of minocycline by inhibition of extracellular matrix metalloproteinase inducer expression following intracerebral hemorrhage in mice.
Liu Y, Li Z, Khan S, Zhang R, Wei R, Zhang Y, Xue M, Yong VW
Neuroscience letters 2021 Nov 1;764:136297
Neuroscience letters 2021 Nov 1;764:136297
Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Kong L, Ma Y, Wang Z, Liu N, Ma G, Liu C, Shi R, Du G
International immunopharmacology 2021 May;94:107507
International immunopharmacology 2021 May;94:107507
Gut-Lung Dysbiosis Accompanied by Diabetes Mellitus Leads to Pulmonary Fibrotic Change through the NF-κB Signaling Pathway.
Wang G, Hu YX, He MY, Xie YH, Su W, Long D, Zhao R, Wang J, Dai C, Li H, Si ZP, Cheng X, Li RM, Li Z, Yang X
The American journal of pathology 2021 May;191(5):838-856
The American journal of pathology 2021 May;191(5):838-856
Interleukin-9 promotes intestinal barrier injury of sepsis: a translational research.
Sun JK, Zhou J, Sun XP, Shen X, Zhu DM, Wang X, Zhou SM, Mu XW
Journal of intensive care 2021 May 3;9(1):37
Journal of intensive care 2021 May 3;9(1):37
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 May 13;27(9):1048-63
CNS neuroscience & therapeutics 2021 May 13;27(9):1048-63
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Xue S, Tang H, Zhao G, Fang C, Shen Y, Yan D, Yuan Y, Fu W, Shi Z, Tang X, Guo D
Free radical biology & medicine 2021 May 1;167:181-192
Free radical biology & medicine 2021 May 1;167:181-192
Interleukin-28A maintains the intestinal epithelial barrier function through regulation of claudin-1.
Li L, Zhou C, Li T, Xiao W, Yu M, Yang H
Annals of translational medicine 2021 Mar;9(5):365
Annals of translational medicine 2021 Mar;9(5):365
Naringenin attenuates experimental autoimmune encephalomyelitis by protecting the intact of blood-brain barrier and controlling inflammatory cell migration.
Niu X, Sang H, Wang J
The Journal of nutritional biochemistry 2021 Mar;89:108560
The Journal of nutritional biochemistry 2021 Mar;89:108560
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Fan L, Peng Y, Wang J, Ma P, Zhao L, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
Liu CD, Liu NN, Zhang S, Ma GD, Yang HG, Kong LL, Du GH
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
l-Arabinose Attenuates Gliadin-Induced Food Allergy via Regulation of Th1/Th2 Balance and Upregulation of Regulatory T Cells in Mice.
Wang Y, Sun J, Xue L, Liu J, Nie C, Fan M, Qian H, Zhang D, Ying H, Li Y, Wang L
Journal of agricultural and food chemistry 2021 Mar 31;69(12):3638-3646
Journal of agricultural and food chemistry 2021 Mar 31;69(12):3638-3646
The effects of myeloablative or non-myeloablative total body irradiations on intestinal tract in mice.
Zhu S, Liang J, Zhu F, Zhang X, Xu M, Zhao K, Zeng L, Xu K
Bioscience reports 2021 Mar 26;41(3)
Bioscience reports 2021 Mar 26;41(3)
Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion.
Wang W, Zhai D, Bai Y, Xue K, Deng L, Ma L, Du T, Ye Z, Qu D, Xiang A, Chen G, Zhao Y, Wang L, Lu Z
Cell death discovery 2021 Mar 23;7(1):58
Cell death discovery 2021 Mar 23;7(1):58
Clostridium Butyricum ZJU-F1 Benefits the Intestinal Barrier Function and Immune Response Associated with Its Modulation of Gut Microbiota in Weaned Piglets.
Fu J, Wang T, Xiao X, Cheng Y, Wang F, Jin M, Wang Y, Zong X
Cells 2021 Mar 2;10(3)
Cells 2021 Mar 2;10(3)
Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice.
Esposito G, Pesce M, Seguella L, Lu J, Corpetti C, Del Re A, De Palma FDE, Esposito G, Sanseverino W, Sarnelli G
International journal of molecular sciences 2021 Mar 14;22(6)
International journal of molecular sciences 2021 Mar 14;22(6)
Dietary seaweed-derived polysaccharides improve growth performance of weaned pigs through maintaining intestinal barrier function and modulating gut microbial populations.
Zou T, Yang J, Guo X, He Q, Wang Z, You J
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Journal of animal science and biotechnology 2021 Mar 10;12(1):28
Contributions of HO-1-Dependent MAPK to Regulating Intestinal Barrier Disruption.
Zhang Z, Zhang Q, Li F, Xin Y, Duan Z
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
Biomolecules & therapeutics 2021 Mar 1;29(2):175-183
A Microfluidic Multisize Spheroid Array for Multiparametric Screening of Anticancer Drugs and Blood-Brain Barrier Transport Properties.
Eilenberger C, Rothbauer M, Selinger F, Gerhartl A, Jordan C, Harasek M, Schädl B, Grillari J, Weghuber J, Neuhaus W, Küpcü S, Ertl P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jun;8(11):e2004856
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Jun;8(11):e2004856
Small Interfering RNA Targeting DMP1 Protects Mice Against Blood-Brain Barrier Disruption and Brain Injury After Intracerebral Hemorrhage.
Shu Y, Huang J, Gao M, Gan S, Zhu S, Xu S, Yang Z, Liao Y, Lu W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2021 Jun;30(6):105760
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
Xu D, Gao Q, Wang F, Peng Q, Wang G, Wei Q, Lei S, Zhao S, Zhang L, Guo F
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
USP9X deubiquitinates connexin43 to prevent high glucose-induced epithelial-to-mesenchymal transition in NRK-52E cells.
Sun XH, Xiao HM, Zhang M, Lin ZY, Yang Y, Chen R, Liu PQ, Huang KP, Huang HQ
Biochemical pharmacology 2021 Jun;188:114562
Biochemical pharmacology 2021 Jun;188:114562
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
Zhuang M, Deng Y, Zhang W, Zhu B, Yan H, Lou J, Zhang P, Cui Q, Tang H, Sun H, Sun Y
Cell death & disease 2021 Jun 9;12(6):595
Cell death & disease 2021 Jun 9;12(6):595
Alisol A 24-acetate protects against brain microvascular endothelial cells injury through inhibiting miR-92a-3p/tight junctions axis.
Lu L, Lu T, Shen J, Lv X, Wei W, Wang H, Xue X
Aging 2021 Jun 4;13(11):15353-15365
Aging 2021 Jun 4;13(11):15353-15365
Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut-Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation.
Yan X, Ren X, Liu X, Wang Y, Ma J, Song R, Wang X, Dong Y, Fan Q, Wei J, Yu A, She G
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7074-7083
Journal of agricultural and food chemistry 2021 Jun 30;69(25):7074-7083
Brain endothelial LRP1 maintains blood-brain barrier integrity.
Storck SE, Kurtyka M, Pietrzik CU
Fluids and barriers of the CNS 2021 Jun 19;18(1):27
Fluids and barriers of the CNS 2021 Jun 19;18(1):27
Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNFα-promotes severe intestinal epithelial dysfunction.
Dutton JS, Hinman SS, Kim R, Attayek PJ, Maurer M, Sims CS, Allbritton NL
Integrative biology : quantitative biosciences from nano to macro 2021 Jun 15;13(6):139-152
Integrative biology : quantitative biosciences from nano to macro 2021 Jun 15;13(6):139-152
Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota.
Chen Y, Zhang H, Chen Y, Jia P, Ji S, Zhang Y, Wang T
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
Journal of animal science and biotechnology 2021 Jun 10;12(1):70
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Lu YZ, Liang LM, Cheng PP, Xiong L, Wang M, Song LJ, Yu F, He XL, Xiong L, Wang XR, Xin JB, Ye H, Ma WL
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Liu FY, Wen J, Hou J, Zhang SQ, Sun CB, Zhou LC, Yin W, Pang WL, Wang C, Ying Y, Han SS, Yan JY, Li CX, Yuan JL, Xing HJ, Yang ZS
International immunopharmacology 2021 Jul;96:107758
International immunopharmacology 2021 Jul;96:107758
Xiao-Xu-Ming decoction prevented hemorrhagic transformation induced by acute hyperglycemia through inhibiting AGE-RAGE-mediated neuroinflammation.
Liu N, Liu C, Yang Y, Ma G, Wei G, Liu S, Kong L, Du G
Pharmacological research 2021 Jul;169:105650
Pharmacological research 2021 Jul;169:105650
Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis.
Wang Y, Guan X, Gao CL, Ruan W, Zhao S, Kai G, Li F, Pang T
Pharmacological research 2021 Jul;169:105640
Pharmacological research 2021 Jul;169:105640
Effects of cigarette smoke on the aggravation of ovalbumin-induced asthma and the expressions of TRPA1 and tight junctions in mice.
Sun YB, Liu M, Fan XS, Zhou LP, Li MW, Hu FY, Yue QF, Zhang YM
Molecular immunology 2021 Jul;135:62-72
Molecular immunology 2021 Jul;135:62-72
A novel PGAM5 inhibitor LFHP-1c protects blood-brain barrier integrity in ischemic stroke.
Gao C, Xu Y, Liang Z, Wang Y, Shang Q, Zhang S, Wang C, Ni M, Wu D, Huang Z, Pang T
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1867-1884
Acta pharmaceutica Sinica. B 2021 Jul;11(7):1867-1884
Protective effects of sulfated polysaccharide from Enterobacter cloacae Z0206 against DSS-induced intestinal injury via DNA methylation.
Zong X, Cheng Y, Xiao X, Fu J, Wang F, Lu Z, Wang Y, Jin M
International journal of biological macromolecules 2021 Jul 31;183:861-869
International journal of biological macromolecules 2021 Jul 31;183:861-869
Effects of Loblolly Pine Biochar and Wood Vinegar on Poultry Litter Nutrients and Microbial Abundance.
Mohammadi-Aragh MK, Stokes CE, Street JT, Linhoss JE
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Animals : an open access journal from MDPI 2021 Jul 26;11(8)
Roux-en-Y gastric bypass potentially improved intestinal permeability by regulating gut innate immunity in diet-induced obese mice.
Jin Z, Chen K, Zhou Z, Peng W, Liu W
Scientific reports 2021 Jul 21;11(1):14894
Scientific reports 2021 Jul 21;11(1):14894
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
Meningitic Escherichia coli α-hemolysin aggravates blood-brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling.
Fu J, Li L, Huo D, Yang R, Yang B, Xu B, Yang X, Dai M, Tan C, Chen H, Wang X
Molecular brain 2021 Jul 19;14(1):116
Molecular brain 2021 Jul 19;14(1):116
Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization.
Fang M, Wan W, Li Q, Wan W, Long Y, Liu H, Yang X
Life sciences 2021 Jul 15;277:119567
Life sciences 2021 Jul 15;277:119567
Sepsis induces variation of intestinal barrier function in different phase through nuclear factor kappa B signaling.
Cao YY, Wang ZH, Xu QC, Chen Q, Wang Z, Lu WH
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Jul 1;25(4):375-383
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2021 Jul 1;25(4):375-383
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling.
Cao YY, Wang Z, Wang ZH, Jiang XG, Lu WH
International immunopharmacology 2021 Jan;90:107218
International immunopharmacology 2021 Jan;90:107218
Scratching damages tight junctions through the Akt-claudin 1 axis in atopic dermatitis.
Hu XQ, Tang Y, Ju Y, Zhang XY, Yan JJ, Wang CM, Yang Y, Zhu C, Tang ZX, Zhou Y, Yu G
Clinical and experimental dermatology 2021 Jan;46(1):74-81
Clinical and experimental dermatology 2021 Jan;46(1):74-81
CD151 Alleviates Early Blood-Brain Barrier Dysfunction After Experimental Focal Brain Ischemia in Rats.
Xu W, Gao C, Wu J
Cellular and molecular neurobiology 2021 Jan;41(1):151-162
Cellular and molecular neurobiology 2021 Jan;41(1):151-162
EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice.
Jia Z, Bao K, Wei P, Yu X, Zhang Y, Wang X, Wang X, Yao L, Li L, Wu P, Yuan W, Wang S, Zheng J, Hua Y, Hong M
Mucosal immunology 2021 Jan;14(1):125-134
Mucosal immunology 2021 Jan;14(1):125-134
Compound sophorae decoction enhances intestinal barrier function of dextran sodium sulfate induced colitis via regulating notch signaling pathway in mice.
Wu H, Chen QY, Wang WZ, Chu S, Liu XX, Liu YJ, Tan C, Zhu F, Deng SJ, Dong YL, Yu T, Gao F, He HX, Leng XY, Fan H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110937
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110937
A Comparison of Chitosan, Mesoporous Silica and Poly(lactic-co-glycolic) Acid Nanocarriers for Optimising Intestinal Uptake of Oral Protein Therapeutics.
Wright L, Joyce P, Barnes TJ, Lundmark R, Bergström CAS, Hubert M, Prestidge CA
Journal of pharmaceutical sciences 2021 Jan;110(1):217-227
Journal of pharmaceutical sciences 2021 Jan;110(1):217-227
Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.
Fu J, Li L, Huo D, Zhi S, Yang R, Yang B, Xu B, Zhang T, Dai M, Tan C, Chen H, Wang X
Brain sciences 2021 Jan 8;11(1)
Brain sciences 2021 Jan 8;11(1)
Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.
Jiang K, Chen H, Fang Y, Chen L, Zhong C, Bu T, Dai S, Pan X, Fu D, Qian Y, Wei J, Ding K
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):21
Journal of experimental & clinical cancer research : CR 2021 Jan 7;40(1):21
Effects of Pinus massoniana pollen polysaccharides on intestinal microenvironment and colitis in mice.
Niu X, Shang H, Chen S, Chen R, Huang J, Miao Y, Cui W, Wang H, Sha Z, Peng D, Zhu R
Food & function 2021 Jan 7;12(1):252-266
Food & function 2021 Jan 7;12(1):252-266
Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model.
Chi H, Cao W, Zhang M, Su D, Yang H, Li Z, Li C, She X, Wang K, Gao X, Ma K, Zheng P, Li X, Cui B
Journal of neuroinflammation 2021 Jan 6;18(1):9
Journal of neuroinflammation 2021 Jan 6;18(1):9
Polystyrene microplastics induced male reproductive toxicity in mice.
Jin H, Ma T, Sha X, Liu Z, Zhou Y, Meng X, Chen Y, Han X, Ding J
Journal of hazardous materials 2021 Jan 5;401:123430
Journal of hazardous materials 2021 Jan 5;401:123430
Effects of different concentrations of coated nano zinc oxide material on fecal bacterial composition and intestinal barrier in weaned piglets.
Liu H, Bai M, Xu K, Zhou J, Zhang X, Yu R, Huang R, Yin Y
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Journal of the science of food and agriculture 2021 Jan 30;101(2):735-745
Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.
Toan NK, Tai NC, Kim SA, Ahn SG
International journal of molecular sciences 2021 Jan 2;22(1)
International journal of molecular sciences 2021 Jan 2;22(1)
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.
Zong X, Xiao X, Kai L, Cheng Y, Fu J, Xu W, Wang Y, Zhao K, Jin M
International journal of biological macromolecules 2021 Jan 15;167:76-84
International journal of biological macromolecules 2021 Jan 15;167:76-84
Antibiotic-induced microbiome depletion in adult mice disrupts blood-brain barrier and facilitates brain infiltration of monocytes after bone-marrow transplantation.
Sun N, Hu H, Wang F, Li L, Zhu W, Shen Y, Xiu J, Xu Q
Brain, behavior, and immunity 2021 Feb;92:102-114
Brain, behavior, and immunity 2021 Feb;92:102-114
Punicalagin Prevents Hepatic Steatosis through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western Diet-Fed Mice.
Liu H, Zhan Q, Miao X, Xia X, Yang G, Peng X, Yan C
Molecular nutrition & food research 2021 Feb;65(4):e2001031
Molecular nutrition & food research 2021 Feb;65(4):e2001031
First evidence of altered microbiota and intestinal damage and their link to absence epilepsy in a genetic animal model, the WAG/Rij rat.
Citraro R, Lembo F, De Caro C, Tallarico M, Coretti L, Iannone LF, Leo A, Palumbo D, Cuomo M, Buommino E, Nesci V, Marascio N, Iannone M, Quirino A, Russo R, Calignano A, Constanti A, Russo E, De Sarro G
Epilepsia 2021 Feb;62(2):529-541
Epilepsia 2021 Feb;62(2):529-541
Val-Val-Tyr-Pro protects against non-alcoholic steatohepatitis in mice by modulating the gut microbiota and gut-liver axis activation.
Xie X, Zhang L, Yuan S, Li H, Zheng C, Xie S, Sun Y, Zhang C, Wang R, Jin Y
Journal of cellular and molecular medicine 2021 Feb;25(3):1439-1455
Journal of cellular and molecular medicine 2021 Feb;25(3):1439-1455
Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis.
Chen J, Chen R, Huang S, Zu B, Zhang S
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Dietary supplementation with glutamine improves gastrointestinal barrier function and promotes compensatory growth of growth-retarded yaks.
Ma J, Shah AM, Wang ZS, Hu R, Zou HW, Wang XY, Zhao SN, Kong XY
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Animal : an international journal of animal bioscience 2021 Feb;15(2):100108
Neutrophil elastase inhibitor (MPH-966) improves intestinal mucosal damage and gut microbiota in a mouse model of 5-fluorouracil-induced intestinal mucositis.
Chen KJ, Chen YL, Ueng SH, Hwang TL, Kuo LM, Hsieh PW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111152
Induction of Epithelial-mesenchymal Transition in MDCK II Cells.
Pastuła A, Lundmark R
Bio-protocol 2021 Feb 5;11(3):e3903
Bio-protocol 2021 Feb 5;11(3):e3903
Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.
Veenstra JP, Vemu B, Tocmo R, Nauman MC, Johnson JJ
Nutrients 2021 Feb 27;13(3)
Nutrients 2021 Feb 27;13(3)
Galli gigeriae endothelium corneum: its intestinal barrier protective activity in vitro and chemical composition.
Li S, Zheng M, Zhang Z, Peng H, Dai W, Liu J
Chinese medicine 2021 Feb 16;16(1):22
Chinese medicine 2021 Feb 16;16(1):22
Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier.
Li J, Zhang L, Wu T, Li Y, Zhou X, Ruan Z
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Journal of agricultural and food chemistry 2021 Feb 10;69(5):1487-1495
Neutrophil extracellular traps induce a hypercoagulable state in glioma.
Zhang S, Guo M, Liu Q, Liu J, Cui Y
Immunity, inflammation and disease 2021 Dec;9(4):1383-1393
Immunity, inflammation and disease 2021 Dec;9(4):1383-1393
Salidroside protects against ventilation-induced lung injury by inhibiting the expression of matrix metalloproteinase-9.
Zhang H, Dong W, Li S, Zhang Y, Lv Z, Yang L, Jiang L, Wu T, Wang Y
Pharmaceutical biology 2021 Dec;59(1):760-768
Pharmaceutical biology 2021 Dec;59(1):760-768
Poly(ADP-ribose) polymerase inhibitor PJ34 protects against UVA-induced oxidative damage in corneal endothelium.
Wang X, Dong C, Zhou Q, Duan H, Zou D, Gong Y, Ma B, Li Z, Shi W
Apoptosis : an international journal on programmed cell death 2021 Dec;26(11-12):600-611
Apoptosis : an international journal on programmed cell death 2021 Dec;26(11-12):600-611
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Chen Y, Zhang H, Ji S, Jia P, Chen Y, Li Y, Wang T
Free radical biology & medicine 2021 Dec;177:1-14
Free radical biology & medicine 2021 Dec;177:1-14
Modified cyclodextrin-based nanoparticles mediated delivery of siRNA for huntingtin gene silencing across an in vitro BBB model.
Mendonça MCP, Cronin MF, Cryan JF, O'Driscoll CM
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2021 Dec;169:309-318
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2021 Dec;169:309-318
Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.
Cao Q, Wei W, Wang H, Wang Z, Lv Y, Dai M, Tan C, Chen H, Wang X
Virulence 2021 Dec;12(1):2296-2313
Virulence 2021 Dec;12(1):2296-2313
Aggregation-Induced Emission (AIE) Nanoparticles-Assisted NIR-II Fluorescence Imaging-Guided Diagnosis and Surgery for Inflammatory Bowel Disease (IBD).
Fan X, Xia Q, Zhang Y, Li Y, Feng Z, Zhou J, Qi J, Tang BZ, Qian J, Lin H
Advanced healthcare materials 2021 Dec;10(24):e2101043
Advanced healthcare materials 2021 Dec;10(24):e2101043
Djulis Hull Improves Insulin Resistance and Modulates the Gut Microbiota in High-Fat Diet (HFD)-Induced Hyperglycaemia.
Tung YT, Zeng JL, Ho ST, Xu JW, Lin IH, Wu JH
Antioxidants (Basel, Switzerland) 2021 Dec 26;11(1)
Antioxidants (Basel, Switzerland) 2021 Dec 26;11(1)
Dose-Dependent Relationship between Protection of Thioacetamide-Induced Acute Liver Injury and Hyperammonemia and Concentration of Lactobacillus salivarius Li01 in Mice.
Lou P, Shen Y, Zhuge A, Lv L, Zhu X, Yuan Y, Yang L, Wang K, Li B, Li L
Microbiology spectrum 2021 Dec 22;9(3):e0184721
Microbiology spectrum 2021 Dec 22;9(3):e0184721
Titanium dioxide nanoparticles perturb the blood-testis barrier via disruption of actin-based cell adhesive function.
Ni DQ, Ma DD, Hao SL, Yang WX, Kovacs T, Tan FQ
Aging 2021 Dec 14;13(23):25440-25452
Aging 2021 Dec 14;13(23):25440-25452
Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice.
Xie X, Zhou J, Hu L, Shu R, Zhang M, Xiong Z, Wu F, Fu Z
Environmental pollution (Barking, Essex : 1987) 2021 Dec 1;290:117934
Environmental pollution (Barking, Essex : 1987) 2021 Dec 1;290:117934
Intrahepatic cholestasis induced by α-naphthylisothiocyanate can cause gut-liver axis disorders.
Chen Z, Wu Y, Wang B, Fang J, Gan C, Sang C, Dun Z, Luosang T, Wang Q, Zeren D, Xiong T
Environmental toxicology and pharmacology 2021 Aug;86:103672
Environmental toxicology and pharmacology 2021 Aug;86:103672
LncRNA-MALAT1/miRNA-204-5p/Smad4 Axis Regulates Epithelial-Mesenchymal Transition, Proliferation and Migration of Lens Epithelial Cells.
Peng C, Wang Y, Ji L, Kuang L, Yu Z, Li H, Zhang J, Zhao J
Current eye research 2021 Aug;46(8):1137-1147
Current eye research 2021 Aug;46(8):1137-1147
Rearrangement of Actin Cytoskeleton by Zika Virus Infection Facilitates Blood-Testis Barrier Hyperpermeability.
Nie Y, Hui L, Guo M, Yang W, Huang R, Chen J, Wen X, Zhao M, Wu Y
Virologica Sinica 2021 Aug;36(4):692-705
Virologica Sinica 2021 Aug;36(4):692-705
GINS2 promotes EMT in pancreatic cancer via specifically stimulating ERK/MAPK signaling.
Huang L, Chen S, Fan H, Ji D, Chen C, Sheng W
Cancer gene therapy 2021 Aug;28(7-8):839-849
Cancer gene therapy 2021 Aug;28(7-8):839-849
Ginsenoside Rk3 alleviates gut microbiota dysbiosis and colonic inflammation in antibiotic-treated mice.
Bai X, Fu R, Duan Z, Wang P, Zhu C, Fan D
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Food research international (Ottawa, Ont.) 2021 Aug;146:110465
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Gao HN, Hu H, Wen PC, Lian S, Xie XL, Song HL, Yang ZN, Ren FZ
Journal of dairy science 2021 Aug;104(8):8411-8424
Journal of dairy science 2021 Aug;104(8):8411-8424
HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization.
Sun W, Li S, Tang G, Sun S, Luo Y, Bai R, Han L, Jiang X, Gao Y, Huang Z, Zhang J, Gong Y, Xie C
Cancer medicine 2021 Aug;10(15):5256-5269
Cancer medicine 2021 Aug;10(15):5256-5269
Aloe polysaccharides ameliorate acute colitis in mice via Nrf2/HO-1 signaling pathway and short-chain fatty acids metabolism.
Liu C, Hua H, Zhu H, Cheng Y, Guo Y, Yao W, Qian H
International journal of biological macromolecules 2021 Aug 31;185:804-812
International journal of biological macromolecules 2021 Aug 31;185:804-812
Effects of Dietary Supplementation of Algae-Derived Polysaccharides on Morphology, Tight Junctions, Antioxidant Capacity and Immune Response of Duodenum in Broilers under Heat Stress.
Liu WC, Zhu YR, Zhao ZH, Jiang P, Yin FQ
Animals : an open access journal from MDPI 2021 Aug 2;11(8)
Animals : an open access journal from MDPI 2021 Aug 2;11(8)
Galacto-oligosaccharides improve barrier function and relieve colonic inflammation via modulating mucosa-associated microbiota composition in lipopolysaccharides-challenged piglets.
Gao R, Tian S, Wang J, Zhu W
Journal of animal science and biotechnology 2021 Aug 11;12(1):92
Journal of animal science and biotechnology 2021 Aug 11;12(1):92
Oxymatrine improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury by downregulating CAV1 and MMP9 expression.
Jiao-Yan Y, Qing-Qing L, Xi L, Mei Z, Ting S, Na H, Wei J, Rui-Tao Z, Peng Y, Qi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Apr;84:153505
Effect of rifaximin on gut-lung axis in mice infected with influenza A virus.
Chen Y, Jiang Z, Lei Z, Ping J, Su J
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Comparative immunology, microbiology and infectious diseases 2021 Apr;75:101611
Glucagon-like peptide 2 attenuates intestinal mucosal barrier injury through the MLCK/pMLC signaling pathway in a piglet model.
Chang Y, Deng Q, Zhang Z, Zhao H, Tang J, Chen X, Liu G, Tian G, Cai J, Jia G
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Journal of cellular physiology 2021 Apr;236(4):3015-3032
Postnatal growth retardation is associated with deteriorated intestinal mucosal barrier function using a porcine model.
Qi M, Tan B, Wang J, Liao S, Li J, Cui Z, Shao Y, Ji P, Yin Y
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Journal of cellular physiology 2021 Apr;236(4):2631-2648
Melatonin exerts protective effects on diabetic retinopathy via inhibition of Wnt/β-catenin pathway as revealed by quantitative proteomics.
Yan M, Wang H, Gu Y, Li X, Tao L, Lu P
Experimental eye research 2021 Apr;205:108521
Experimental eye research 2021 Apr;205:108521
Multiple roles of FGF10 in the regulation of corneal endothelial wound healing.
Wang X, Zhou Q, Zhao C, Duan H, Li W, Dong C, Gong Y, Li Z, Shi W
Experimental eye research 2021 Apr;205:108517
Experimental eye research 2021 Apr;205:108517
Effects of the extract from peanut meal fermented with Bacillus natto and Monascus on lipid metabolism and intestinal barrier function of hyperlipidemic mice.
Lu Y, Ding H, Jiang X, Zhang H, Ma A, Hu Y, Li Z
Journal of the science of food and agriculture 2021 Apr;101(6):2561-2569
Journal of the science of food and agriculture 2021 Apr;101(6):2561-2569
Ginsenoside Rh4 alleviates antibiotic-induced intestinal inflammation by regulating the TLR4-MyD88-MAPK pathway and gut microbiota composition.
Bai X, Fu R, Duan Z, Liu Y, Zhu C, Fan D
Food & function 2021 Apr 7;12(7):2874-2885
Food & function 2021 Apr 7;12(7):2874-2885
Transwell Insert-Embedded Microfluidic Devices for Time-Lapse Monitoring of Alveolar Epithelium Barrier Function under Various Stimulations.
Chang SH, Ko PL, Liao WH, Peng CC, Tung YC
Micromachines 2021 Apr 6;12(4)
Micromachines 2021 Apr 6;12(4)
Impaired Colonic Contractility and Intestinal Permeability in Symptomatic Uncomplicated Diverticular Disease.
Altomare A, Gori M, Cocca S, Carotti S, Francesconi M, Ribolsi M, Emerenziani S, Perrone G, Morini S, Cicala M, Guarino MPL
Journal of neurogastroenterology and motility 2021 Apr 30;27(2):292-301
Journal of neurogastroenterology and motility 2021 Apr 30;27(2):292-301
Exosomes derived from HeLa cells break down vascular integrity by triggering endoplasmic reticulum stress in endothelial cells.
Lin Y, Zhang C, Xiang P, Shen J, Sun W, Yu H
Journal of extracellular vesicles 2020;9(1):1722385
Journal of extracellular vesicles 2020;9(1):1722385
Molecular mechanism mediating enteric bacterial translocation after severe burn: the role of cystic fibrosis transmembrane conductance regulator.
Liu X, Chen Y, You B, Peng Y, Chen Y, Yang Z, Zhang Y, Chen J
Burns & trauma 2020;9:tkaa042
Burns & trauma 2020;9:tkaa042
Comparing the gastrointestinal barrier function between growth-retarded and normal yaks on the Qinghai-Tibetan Plateau.
Ma J, Shah AM, Wang Z, Hu R, Zou H, Wang X, Cao G, Peng Q, Xue B, Wang L, Zhao S, Kong X
PeerJ 2020;8:e9851
PeerJ 2020;8:e9851
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1.
Yang F, Zhang Y, Zhu J, Wang J, Jiang Z, Zhao C, Yang Q, Huang Y, Yao W, Pang W, Han L, Zhou J
Frontiers in bioengineering and biotechnology 2020;8:647
Frontiers in bioengineering and biotechnology 2020;8:647
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism.
Chen X, Deng S, Lei Q, He Q, Ren Y, Zhang Y, Nie J, Lu W
Frontiers in cell and developmental biology 2020;8:598020
Frontiers in cell and developmental biology 2020;8:598020
The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation.
Nettleford SK, Zhao L, Qian F, Herold M, Arner B, Desai D, Amin S, Xiong N, Singh V, Carlson BA, Prabhu KS
Frontiers in nutrition 2020;7:96
Frontiers in nutrition 2020;7:96
Teasaponin Ameliorates Murine Colitis by Regulating Gut Microbiota and Suppressing the Immune System Response.
Yang H, Cai R, Kong Z, Chen Y, Cheng C, Qi S, Gu B
Frontiers in medicine 2020;7:584369
Frontiers in medicine 2020;7:584369
Koumine Alleviates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction in IPEC-J2 Cells by Regulating Nrf2/NF-κB Pathway.
Wu J, Yang CL, Sha YK, Wu Y, Liu ZY, Yuan ZH, Sun ZL
The American journal of Chinese medicine 2020;48(1):127-142
The American journal of Chinese medicine 2020;48(1):127-142
ROS Plays a Role in the Neonatal Rat Intestinal Barrier Damages Induced by Hyperoxia.
Liu DY, Lou WJ, Zhang DY, Sun SY
BioMed research international 2020;2020:8819195
BioMed research international 2020;2020:8819195
Cholic Acid Protects In Vitro Neurovascular Units against Oxygen and Glucose Deprivation-Induced Injury through the BDNF-TrkB Signaling Pathway.
Li C, Wang X, Yan J, Cheng F, Ma X, Chen C, Wang W, Wang Q
Oxidative medicine and cellular longevity 2020;2020:1201624
Oxidative medicine and cellular longevity 2020;2020:1201624
Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota.
Wang W, Zhong M, Yu T, Chen L, Shi L, Zong J, Wang S
Nutrition & metabolism 2020;17:27
Nutrition & metabolism 2020;17:27
Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet.
Chen L, Zhang L, Wang W, Qiu W, Liu L, Ning A, Cao J, Huang M, Zhong M
PloS one 2020;15(6):e0232972
PloS one 2020;15(6):e0232972
Inhibition of NOX4/ROS Suppresses Neuronal and Blood-Brain Barrier Injury by Attenuating Oxidative Stress After Intracerebral Hemorrhage.
Xie J, Hong E, Ding B, Jiang W, Zheng S, Xie Z, Tian D, Chen Y
Frontiers in cellular neuroscience 2020;14:578060
Frontiers in cellular neuroscience 2020;14:578060
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
Zou X, Wang Y, Wang Y, Yang J, Guo H, Cai Z
Drug design, development and therapy 2020;14:5623-5632
Drug design, development and therapy 2020;14:5623-5632
Bloodletting Puncture at Hand Twelve Jing-Well Points Improves Neurological Recovery by Ameliorating Acute Traumatic Brain Injury-Induced Coagulopathy in Mice.
Li B, Zhou X, Yi TL, Xu ZW, Peng DW, Guo Y, Guo YM, Cao YL, Zhu L, Zhang S, Cheng SX
Frontiers in neuroscience 2020;14:403
Frontiers in neuroscience 2020;14:403
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
Zhong M, Zhu M, Liu Y, Lin Y, Wang L, Ye Y, Chen H, Yang Y, Zhuang G, Huang J
Journal of Cancer 2020;11(10):3061-3071
Journal of Cancer 2020;11(10):3061-3071
Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets.
Hu R, He Z, Liu M, Tan J, Zhang H, Hou DX, He J, Wu S
Journal of animal science and biotechnology 2020;11:92
Journal of animal science and biotechnology 2020;11:92
H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated Nucleotide Binding Oligomerization Domain-Like Receptor Protein 3 Inflammasome Activation in Retinopathy Induced by Hyperglycemia.
Yang K, Liu J, Zhang X, Ren Z, Gao L, Wang Y, Lin W, Ma X, Hao M, Kuang H
Frontiers in pharmacology 2020;11:603689
Frontiers in pharmacology 2020;11:603689
Screening, Safety Evaluation, and Mechanism of Two Lactobacillus fermentum Strains in Reducing the Translocation of Staphylococcus aureus in the Caco-2 Monolayer Model.
Peng Z, Wei B, Huang T, Liu Z, Guan Q, Xie M, Li H, Xiong T
Frontiers in microbiology 2020;11:566473
Frontiers in microbiology 2020;11:566473
Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets.
Zhang H, Chen Y, Chen Y, Ji S, Jia P, Li Y, Wang T
Journal of animal science and biotechnology 2020;11:52
Journal of animal science and biotechnology 2020;11:52
Taurine Alleviates Intestinal Injury by Mediating Tight Junction Barriers in Diquat-Challenged Piglet Models.
Wen C, Guo Q, Wang W, Duan Y, Zhang L, Li J, He S, Chen W, Li F
Frontiers in physiology 2020;11:449
Frontiers in physiology 2020;11:449
Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells.
He S, Guo Y, Zhao J, Xu X, Wang N, Liu Q
Frontiers in pharmacology 2020;11:376
Frontiers in pharmacology 2020;11:376
1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea Protects the Blood-Brain Barrier Against Ischemic Injury by Upregulating Tight Junction Protein Expression, Mitigating Apoptosis and Inflammation In Vivo and In Vitro Model.
Yi X, Xu C, Huang P, Zhang L, Qing T, Li J, Wang C, Zeng T, Lu J, Han Z
Frontiers in pharmacology 2020;11:1197
Frontiers in pharmacology 2020;11:1197
Effect of Xiaoyaosan on Colon Morphology and Intestinal Permeability in Rats With Chronic Unpredictable Mild Stress.
Ding F, Wu J, Liu C, Bian Q, Qiu W, Ma Q, Li X, Long M, Zou X, Chen J
Frontiers in pharmacology 2020;11:1069
Frontiers in pharmacology 2020;11:1069
Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.
Lv W, Graves DT, He L, Shi Y, Deng X, Zhao Y, Dong X, Ren Y, Liu X, Xiao E, Zhang Y
Theranostics 2020;10(14):6500-6516
Theranostics 2020;10(14):6500-6516
Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae.
Yang T, Heydarian M, Kozjak-Pavlovic V, Urban M, Harbottle RP, Rudel T
Frontiers in cellular and infection microbiology 2020;10:422
Frontiers in cellular and infection microbiology 2020;10:422
Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice.
Liu Y, Ma Y, Du B, Wang Y, Yang GY, Bi X
Molecular neurobiology 2020 Sep;57(9):3891-3901
Molecular neurobiology 2020 Sep;57(9):3891-3901
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Shi L, Liu BY, Wang X, Zhu MJ, Chen L, Zhou MY, Gu YJ, Cheng L, Wang Y
Cell stress & chaperones 2020 Sep;25(5):793-802
Cell stress & chaperones 2020 Sep;25(5):793-802
Characterization of Low Molecular Weight Sulfate Ulva Polysaccharide and its Protective Effect against IBD in Mice.
Li Y, Ye H, Wang T, Wang P, Liu R, Li Y, Tian Y, Zhang J
Marine drugs 2020 Sep 29;18(10)
Marine drugs 2020 Sep 29;18(10)
Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids.
Yoshimoto S, Yoshizumi J, Anzai H, Morishita K, Okamura K, Hiraki A, Hashimoto S
Disease models & mechanisms 2020 Sep 28;13(9)
Disease models & mechanisms 2020 Sep 28;13(9)
IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier.
Furutama D, Matsuda S, Yamawaki Y, Hatano S, Okanobu A, Memida T, Oue H, Fujita T, Ouhara K, Kajiya M, Mizuno N, Kanematsu T, Tsuga K, Kurihara H
Brain sciences 2020 Sep 27;10(10)
Brain sciences 2020 Sep 27;10(10)
Chronic minocycline treatment exerts antidepressant effect, inhibits neuroinflammation, and modulates gut microbiota in mice.
Yang Q, Luo L, Sun T, Yang L, Cheng LF, Wang Y, Liu QQ, Liu A, Liu HY, Zhao MG, Wu SX, Feng B
Psychopharmacology 2020 Oct;237(10):3201-3213
Psychopharmacology 2020 Oct;237(10):3201-3213
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening.
Sondorp LHJ, Ogundipe VML, Groen AH, Kelder W, Kemper A, Links TP, Coppes RP, Kruijff S
Cancers 2020 Oct 31;12(11)
Cancers 2020 Oct 31;12(11)
Salvianolic acid B prevents body weight gain and regulates gut microbiota and LPS/TLR4 signaling pathway in high-fat diet-induced obese mice.
Li L, Li R, Zhu R, Chen B, Tian Y, Zhang H, Xia B, Jia Q, Wang L, Zhao D, Mo F, Li Y, Zhang S, Gao S, Zhang D, Guo S
Food & function 2020 Oct 21;11(10):8743-8756
Food & function 2020 Oct 21;11(10):8743-8756
Bioinformatics analysis of LINC01554 and its co‑expressed genes in hepatocellular carcinoma.
Li L, Huang K, Lu Z, Zhao H, Li H, Ye Q, Peng G
Oncology reports 2020 Nov;44(5):2185-2197
Oncology reports 2020 Nov;44(5):2185-2197
Protective effect of Lactobacillus salivarius Li01 on thioacetamide-induced acute liver injury and hyperammonaemia.
Yang L, Bian X, Wu W, Lv L, Li Y, Ye J, Jiang X, Wang Q, Shi D, Fang D, Wu J, Wang K, Wang Q, Xia J, Xie J, Lu Y, Li L
Microbial biotechnology 2020 Nov;13(6):1860-1876
Microbial biotechnology 2020 Nov;13(6):1860-1876
Anthocyanins decrease the internalization of TiO(2) nanoparticles into 3D Caco-2 spheroids.
Wang J, Zhang J, Li S, Huang C, Xie Y, Cao Y
Food chemistry 2020 Nov 30;331:127360
Food chemistry 2020 Nov 30;331:127360
Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier.
Jiang Z, Mu W, Yang Y, Sun M, Liu Y, Gao Z, Li J, Gu P, Wang H, Lu Y, Ba Q, Wang H
The Science of the total environment 2020 Nov 20;744:140844
The Science of the total environment 2020 Nov 20;744:140844
Novel Pentapeptide Derived from Chicken by-Product Ameliorates DSS-Induced Colitis by Enhancing Intestinal Barrier Function via AhR-Induced Src Inactivation.
Li S, Ma B, Wang J, Peng H, Zheng M, Dai W, Liu J
Journal of agricultural and food chemistry 2020 Nov 19;
Journal of agricultural and food chemistry 2020 Nov 19;
Crocin-I alleviates the depression-like behaviors probably via modulating "microbiota-gut-brain" axis in mice exposed to chronic restraint stress.
Xiao Q, Shu R, Wu C, Tong Y, Xiong Z, Zhou J, Yu C, Xie X, Fu Z
Journal of affective disorders 2020 Nov 1;276:476-486
Journal of affective disorders 2020 Nov 1;276:476-486
Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway.
Jia Y, Cui R, Wang C, Feng Y, Li Z, Tong Y, Qu K, Liu C, Zhang J
Redox biology 2020 May;32:101534
Redox biology 2020 May;32:101534
Effect of MicroRNA-126a-3p on Bone Marrow Mesenchymal Stem Cells Repairing Blood-brain Barrier and Nerve Injury after Intracerebral Hemorrhage.
Wang C, Cao J, Duan S, Xu R, Yu H, Huo X, Qian Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 May;29(5):104748
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2020 May;29(5):104748
Small airway remodeling in diabetic and smoking chronic obstructive pulmonary disease patients.
Wu N, Wu Z, Sun J, Yan M, Wang B, Du X, Liu Y
Aging 2020 May 5;12(9):7927-7944
Aging 2020 May 5;12(9):7927-7944
Exposure to nonylphenol in early life increases pro-inflammatory cytokines in the prefrontal cortex: Involvement of gut-brain communication.
Che X, Fang Y, You M, Xu Y, Wang Y
Chemico-biological interactions 2020 May 25;323:109076
Chemico-biological interactions 2020 May 25;323:109076
Palmitic Acid Affects Intestinal Epithelial Barrier Integrity and Permeability In Vitro.
Gori M, Altomare A, Cocca S, Solida E, Ribolsi M, Carotti S, Rainer A, Francesconi M, Morini S, Cicala M, Guarino MPL
Antioxidants (Basel, Switzerland) 2020 May 13;9(5)
Antioxidants (Basel, Switzerland) 2020 May 13;9(5)
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Wu DM, Deng SH, Zhou J, Han R, Liu T, Zhang T, Li J, Chen JP, Xu Y
International journal of cancer 2020 May 1;146(9):2563-2575
International journal of cancer 2020 May 1;146(9):2563-2575
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Wang X, Liu M, Zhu MJ, Shi L, Liu L, Zhao YL, Cheng L, Gu YJ, Zhou MY, Chen L, Kumar A, Wang Y
Cell proliferation 2020 Mar;53(3):e12773
Cell proliferation 2020 Mar;53(3):e12773
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice.
Huang M, Wang Q, Long F, Di Y, Wang J, Zhun Zhu Y, Liu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4107-4119
Protective role of berberine on ulcerative colitis through modulating enteric glial cells-intestinal epithelial cells-immune cells interactions.
Li H, Fan C, Lu H, Feng C, He P, Yang X, Xiang C, Zuo J, Tang W
Acta pharmaceutica Sinica. B 2020 Mar;10(3):447-461
Acta pharmaceutica Sinica. B 2020 Mar;10(3):447-461
Parecoxib exhibits anti-inflammatory and neuroprotective effects in a rat model of transient global cerebral ischemia.
Liu S, Dai Y, Zhou C, Zhu T
Journal of toxicology and environmental health. Part A 2020 Mar 3;83(5):203-214
Journal of toxicology and environmental health. Part A 2020 Mar 3;83(5):203-214
A PTAL-miR-101-FN1 Axis Promotes EMT and Invasion-Metastasis in Serous Ovarian Cancer.
Liang H, Yu M, Yang R, Zhang L, Zhang L, Zhu D, Luo H, Hong Y, Yu T, Sun J, Shan H, Gu Y
Molecular therapy oncolytics 2020 Mar 27;16:53-62
Molecular therapy oncolytics 2020 Mar 27;16:53-62
Jiao-tai-wan inhibits inflammation of the gut-brain-axis and attenuates cognitive impairment in insomnic rats.
Su H, Zhang C, Zou X, Lu F, Zeng Y, Guan H, Ren Y, Yuan F, Xu L, Zhang M, Dong H
Journal of ethnopharmacology 2020 Mar 25;250:112478
Journal of ethnopharmacology 2020 Mar 25;250:112478
Methamphetamine-induced alterations in intestinal mucosal barrier function occur via the microRNA-181c/ TNF-α/tight junction axis.
Shen S, Zhao J, Dai Y, Chen F, Zhang Z, Yu J, Wang K
Toxicology letters 2020 Mar 15;321:73-82
Toxicology letters 2020 Mar 15;321:73-82
Mutual regulation between butyrate and hypoxia-inducible factor-1α in epithelial cell promotes expression of tight junction proteins.
Yin J, Zhou C, Yang K, Ren Y, Qiu Y, Xu P, Xiao W, Yang H
Cell biology international 2020 Jun;44(6):1405-1414
Cell biology international 2020 Jun;44(6):1405-1414
Heme protects intestinal mucosal barrier in DSS-induced colitis through regulating macrophage polarization in both HO-1-dependent and HO-1-independent way.
Wu Y, Wu B, Zhang Z, Lu H, Fan C, Qi Q, Gao Y, Li H, Feng C, Zuo J, Tang W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8028-8043
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8028-8043
CD147 Promoted Epithelial Mesenchymal Transition in Airway Epithelial Cells Induced by Cigarette Smoke via Oxidative Stress Signaling Pathway.
Zhou H, Liu Y, Wang Z, Yang Y, Li M, Yuan D, Zhang X, Li Y
COPD 2020 Jun;17(3):269-279
COPD 2020 Jun;17(3):269-279
microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.
Wu J, He J, Tian X, Luo Y, Zhong J, Zhang H, Li H, Cen B, Jiang T, Sun X
Journal of neurochemistry 2020 Jun;153(6):710-726
Journal of neurochemistry 2020 Jun;153(6):710-726
ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch.
Shimizu A, Goh WH, Itai S, Hashimoto M, Miura S, Onoe H
Lab on a chip 2020 Jun 2;20(11):1917-1927
Lab on a chip 2020 Jun 2;20(11):1917-1927
Ursodeoxycholic Acid Halts Pathological Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy.
Thounaojam MC, Jadeja RN, Rajpurohit S, Gutsaeva DR, Stansfield BK, Martin PM, Bartoli M
Journal of clinical medicine 2020 Jun 19;9(6)
Journal of clinical medicine 2020 Jun 19;9(6)
Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease.
Uemasu K, Tanabe N, Tanimura K, Hasegawa K, Mizutani T, Hamakawa Y, Sato S, Ogawa E, Thomas MJ, Ikegami M, Muro S, Hirai T, Sato A
American journal of respiratory cell and molecular biology 2020 Jul;63(1):67-78
American journal of respiratory cell and molecular biology 2020 Jul;63(1):67-78
TBC1D20 Is Essential for Mouse Blood-Testis Barrier Integrity Through Maintaining the Epithelial Phenotype and Modulating the Maturation of Sertoli Cells.
Cui L, Gu Y, Liu S, Li M, Ye J, Zhang F, Luo X, Chang WL, Gui Y
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jul;27(7):1443-1454
Reproductive sciences (Thousand Oaks, Calif.) 2020 Jul;27(7):1443-1454
Platelet regulates neuroinflammation and restores blood-brain barrier integrity in a mouse model of traumatic brain injury.
Gao C, Wang H, Wang T, Luo C, Wang Z, Zhang M, Chen X, Tao L
Journal of neurochemistry 2020 Jul;154(2):190-204
Journal of neurochemistry 2020 Jul;154(2):190-204
Connexin 43 prevents the progression of diabetic renal tubulointerstitial fibrosis by regulating the SIRT1-HIF-1α signaling pathway.
Sun X, Huang K, Haiming X, Lin Z, Yang Y, Zhang M, Liu P, Huang H
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1573-1592
Clinical science (London, England : 1979) 2020 Jul 17;134(13):1573-1592
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis.
Bai R, Sun D, Chen M, Shi X, Luo L, Yao Z, Liu Y, Ge X, Gao X, Hu GF, Zhou W, Sheng J, Xu Z
The EMBO journal 2020 Jul 1;39(13):e103325
The EMBO journal 2020 Jul 1;39(13):e103325
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Zhu C, Zhao L, Zhao J, Zhang S
International journal of molecular medicine 2020 Jan;45(1):53-60
International journal of molecular medicine 2020 Jan;45(1):53-60
Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.
Guo F, Xu D, Lin Y, Wang G, Wang F, Gao Q, Wei Q, Lei S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884
Effects of oral florfenicol on intestinal structure, function and microbiota in mice.
Yun S, Guo Y, Yang L, Zhang X, Shen W, Wang Z, Wen S, Zhao D, Wu H, Chen J, Sun Y, Duan Z
Archives of microbiology 2020 Jan;202(1):161-169
Archives of microbiology 2020 Jan;202(1):161-169
Identification of differentially expressed genes and signaling pathways involved in endometriosis by integrated bioinformatics analysis.
Dai FF, Bao AY, Luo B, Zeng ZH, Pu XL, Wang YQ, Zhang L, Xian S, Yuan MQ, Yang DY, Liu SY, Cheng YX
Experimental and therapeutic medicine 2020 Jan;19(1):264-272
Experimental and therapeutic medicine 2020 Jan;19(1):264-272
Protective Effect of Naringin on In Vitro Gut-Vascular Barrier Disruption of Intestinal Microvascular Endothelial Cells Induced by TNF-α.
Liu P, Bian Y, Fan Y, Zhong J, Liu Z
Journal of agricultural and food chemistry 2020 Jan 8;68(1):168-175
Journal of agricultural and food chemistry 2020 Jan 8;68(1):168-175
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Jiang YP, Ye RJ, Yang JM, Liu N, Zhang WJ, Ma L, Sun T, Niu JG, Zheng P, Yu JQ
Chemico-biological interactions 2020 Jan 5;315:108869
Chemico-biological interactions 2020 Jan 5;315:108869
Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion.
Lu Z, Zhang D, Cui K, Fu X, Man J, Lu H, Yu L, Gao Y, Liu X, Liao L, Li X, Liu C, Zhang Y, Zhang Z, Wang J
Neuroscience 2020 Jan 21;428:228-241
Neuroscience 2020 Jan 21;428:228-241
Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling.
Sheng W, Shi X, Lin Y, Tang J, Jia C, Cao R, Sun J, Wang G, Zhou L, Dong M
Journal of experimental & clinical cancer research : CR 2020 Jan 17;39(1):16
Journal of experimental & clinical cancer research : CR 2020 Jan 17;39(1):16
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Melatonin protects the mouse testis against heat-induced damage.
Zhang P, Zheng Y, Lv Y, Li F, Su L, Qin Y, Zeng W
Molecular human reproduction 2020 Feb 29;26(2):65-79
Molecular human reproduction 2020 Feb 29;26(2):65-79
Peripheral inflammation promotes brain tau transmission via disrupting blood-brain barrier.
Liu Y, Zhang S, Li X, Liu E, Wang X, Zhou Q, Ye J, Wang JZ
Bioscience reports 2020 Feb 28;40(2)
Bioscience reports 2020 Feb 28;40(2)
Environmental lead exposure aggravates the progression of Alzheimer's disease in mice by targeting on blood brain barrier.
Wu S, Liu H, Zhao H, Wang X, Chen J, Xia D, Xiao C, Cheng J, Zhao Z, He Y
Toxicology letters 2020 Feb 1;319:138-147
Toxicology letters 2020 Feb 1;319:138-147
Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice.
Wang S, Chen Q, Zhang Y, Zheng F, Xue T, Ge X, Ma R, Li X, Wu R, Liang K, Qian Z, Ge Y, Ma J, Yao B
Reproductive toxicology (Elmsford, N.Y.) 2020 Dec;98:233-241
Reproductive toxicology (Elmsford, N.Y.) 2020 Dec;98:233-241
Impact of uric acid on liver injury and intestinal permeability following resuscitated hemorrhagic shock in rats.
Khazoom F, L'Écuyer S, Gilbert K, Gagné MA, Bouchard C, Rose CF, Rousseau G, Charbonney E
The journal of trauma and acute care surgery 2020 Dec;89(6):1076-1084
The journal of trauma and acute care surgery 2020 Dec;89(6):1076-1084
MMP7 damages the integrity of the renal tubule epithelium by activating MMP2/9 during ischemia-reperfusion injury.
Hu Q, Lan J, Liang W, Chen Y, Chen B, Liu Z, Xiong Y, Zhong Z, Wang Y, Ye Q
Journal of molecular histology 2020 Dec;51(6):685-700
Journal of molecular histology 2020 Dec;51(6):685-700
Icariside II attenuates cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction in rats via regulating the balance of MMP9/TIMP1.
Liu MB, Wang W, Gao JM, Li F, Shi JS, Gong QH
Acta pharmacologica Sinica 2020 Dec;41(12):1547-1556
Acta pharmacologica Sinica 2020 Dec;41(12):1547-1556
Inhibition of miRNA-29a regulates intestinal barrier function in diarrhea-predominant irritable bowel syndrome by upregulating ZO-1 and CLDN1.
Zhu H, Xiao X, Shi Y, Wu Y, Huang Y, Li D, Xiong F, He G, Chai Y, Tang H
Experimental and therapeutic medicine 2020 Dec;20(6):155
Experimental and therapeutic medicine 2020 Dec;20(6):155
Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice.
Chen Q, Wang Y, Jiao F, Shi C, Pei M, Wang L, Gong Z
Scientific reports 2020 Dec 14;10(1):21850
Scientific reports 2020 Dec 14;10(1):21850
Polysaccharide from the seeds of Plantago asiatica L. alleviates nonylphenol induced intestinal barrier injury by regulating tight junctions in human Caco-2 cell line.
Li F, Du P, Yang W, Huang D, Nie S, Xie M
International journal of biological macromolecules 2020 Dec 1;164:2134-2140
International journal of biological macromolecules 2020 Dec 1;164:2134-2140
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway.
Tian M, Ma P, Zhang Y, Mi Y, Fan D
International immunopharmacology 2020 Aug;85:106645
International immunopharmacology 2020 Aug;85:106645
Nrf2 activation ameliorates mechanical allodynia in paclitaxel-induced neuropathic pain.
Zhou YQ, Liu DQ, Chen SP, Chen N, Sun J, Wang XM, Cao F, Tian YK, Ye DW
Acta pharmacologica Sinica 2020 Aug;41(8):1041-1048
Acta pharmacologica Sinica 2020 Aug;41(8):1041-1048
Salvianolic acid B protects against myocardial ischaemia-reperfusion injury in rats via inhibiting high mobility group box 1 protein expression through the PI3K/Akt signalling pathway.
Liu H, Liu W, Qiu H, Zou D, Cai H, Chen Q, Zheng C, Xu D
Naunyn-Schmiedeberg's archives of pharmacology 2020 Aug;393(8):1527-1539
Naunyn-Schmiedeberg's archives of pharmacology 2020 Aug;393(8):1527-1539
A self-driven bioinspired nanovehicle by leukocyte membrane-hitchhiking for early detection and treatment of atherosclerosis.
Wu G, Wei W, Zhang J, Nie W, Yuan L, Huang Y, Zuo L, Huang L, Xi X, Xie HY
Biomaterials 2020 Aug;250:119963
Biomaterials 2020 Aug;250:119963
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Cong LH, Li T, Wang H, Wu YN, Wang SP, Zhao YY, Zhang GQ, Duan J
Journal of cellular and molecular medicine 2020 Aug;24(15):8532-8544
Journal of cellular and molecular medicine 2020 Aug;24(15):8532-8544
Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit.
Wu J, He J, Tian X, Zhong J, Li H, Sun X
Translational stroke research 2020 Aug;11(4):720-733
Translational stroke research 2020 Aug;11(4):720-733
Localization of ZIP14 and ZIP8 in HIBCPP Cells.
Morgan SE, Schroten H, Ishikawa H, Zhao N
Brain sciences 2020 Aug 8;10(8)
Brain sciences 2020 Aug 8;10(8)
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Tan J, Liu H, Huang M, Li N, Tang S, Meng J, Tang S, Zhou H, Kijlstra A, Yang P, Hou S
Cell death & disease 2020 Aug 22;11(8):697
Cell death & disease 2020 Aug 22;11(8):697
Metformin therapy confers cardioprotection against the remodeling of gap junction in tachycardia-induced atrial fibrillation dog model.
Li J, Li B, Bai F, Ma Y, Liu N, Liu Y, Wang Y, Liu Q
Life sciences 2020 Aug 1;254:117759
Life sciences 2020 Aug 1;254:117759
Responses of intestinal morphology and function in offspring to heat stress in primiparous sows during late gestation.
Guo H, He J, Yang X, Zheng W, Yao W
Journal of thermal biology 2020 Apr;89:102539
Journal of thermal biology 2020 Apr;89:102539
Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice.
Li P, Wu M, Xiong W, Li J, An Y, Ren J, Xie Y, Xue H, Yan D, Li M, Zhong G
International immunopharmacology 2020 Apr;81:106288
International immunopharmacology 2020 Apr;81:106288
Protective effect of Dioscorea zingiberensis ethanol extract on the disruption of blood-testes barrier in high-fat diet/streptozotocin-induced diabetic mice by upregulating ZO-1 and Nrf2.
Zhou J, Xi Y, Zhang J, Tang J, Zhou X, Chen J, Nie C, Zhu Z, Ma B
Andrologia 2020 Apr;52(3):e13508
Andrologia 2020 Apr;52(3):e13508
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
Bai L, Liang J, Li L, Li E
Oncology reports 2020 Apr;43(4):1208-1220
Oncology reports 2020 Apr;43(4):1208-1220
Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage.
Li X, Yao Z, Yang D, Jiang X, Sun J, Tian L, Hu J, Wu B, Bai W
Journal of hazardous materials 2020 Apr 5;387:121706
Journal of hazardous materials 2020 Apr 5;387:121706
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
He J, Jiang YL, Wang Y, Tian XJ, Sun SR
Chinese medical journal 2020 Apr 5;133(7):800-807
Chinese medical journal 2020 Apr 5;133(7):800-807
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis.
Li H, Feng C, Fan C, Yang Y, Yang X, Lu H, Lu Q, Zhu F, Xiang C, Zhang Z, He P, Zuo J, Tang W
Cell death & disease 2020 Apr 24;11(4):271
Cell death & disease 2020 Apr 24;11(4):271
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage.
Li M, Liu G, Wang K, Wang L, Fu X, Lim LY, Chen W, Mo J
Journal of nanobiotechnology 2020 Apr 19;18(1):61
Journal of nanobiotechnology 2020 Apr 19;18(1):61
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
Cheng Y, Wu T, Tang S, Liang F, Fang Y, Cao W, Pan S, Xu X
Food & function 2020 Apr 1;11(4):3167-3179
Food & function 2020 Apr 1;11(4):3167-3179
Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development.
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L
Theranostics 2019;9(17):5065-5084
Theranostics 2019;9(17):5065-5084
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291
Frontiers in oncology 2019;9:291
Building a Thick Mucus Hydrogel Layer to Improve the Physiological Relevance of In Vitro Primary Colonic Epithelial Models.
Wang Y, Kim R, Sims CE, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2019;8(4):653-655.e5
Cellular and molecular gastroenterology and hepatology 2019;8(4):653-655.e5
Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds.
Li D, Yuan D, Shen H, Mao X, Yuan S, Liu Q
Molecular vision 2019;25:625-635
Molecular vision 2019;25:625-635
Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
Guo Y, Huang C, Liu L, Fu X, Lu Y, Zheng J, Mei Q, Huang Z, Fan J, Lu L, Zeng Y
Mediators of inflammation 2019;2019:8474523
Mediators of inflammation 2019;2019:8474523
Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway.
Zhuang Y, Wu H, Wang X, He J, He S, Yin Y
Oxidative medicine and cellular longevity 2019;2019:7591840
Oxidative medicine and cellular longevity 2019;2019:7591840
Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis.
Yan Z, Yang F, Hong Z, Wang S, Jinjuan Z, Han B, Xie R, Leng F, Yang Q
Canadian journal of gastroenterology & hepatology 2019;2019:5236149
Canadian journal of gastroenterology & hepatology 2019;2019:5236149
High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis.
Su YR, Hong YP, Mei FC, Wang CY, Li M, Zhou Y, Zhao KL, Yu J, Wang WX
Mediators of inflammation 2019;2019:2512687
Mediators of inflammation 2019;2019:2512687
Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking.
Speer JE, Gunasekara DB, Wang Y, Fallon JK, Attayek PJ, Smith PC, Sims CE, Allbritton NL
Journal of biological engineering 2019;13:36
Journal of biological engineering 2019;13:36
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Tang G, Zeng Z, Sun W, Li S, You C, Tang F, Peng S, Ma S, Luo Y, Xu J, Tian X, Zhang N, Gong Y, Xie C
Journal of Cancer 2019;10(10):2261-2275
Journal of Cancer 2019;10(10):2261-2275
Pinocembrin Protects Against Dextran Sulfate Sodium-Induced Rats Colitis by Ameliorating Inflammation, Improving Barrier Function and Modulating Gut Microbiota.
Hu L, Wu C, Zhang Z, Liu M, Maruthi Prasad E, Chen Y, Wang K
Frontiers in physiology 2019;10:908
Frontiers in physiology 2019;10:908
A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function.
Gao J, Li Y, Wan Y, Hu T, Liu L, Yang S, Gong Z, Zeng Q, Wei Y, Yang W, Zeng Z, He X, Huang SH, Cao H
Frontiers in microbiology 2019;10:477
Frontiers in microbiology 2019;10:477
Licochalcone A Protects the Blood-Milk Barrier Integrity and Relieves the Inflammatory Response in LPS-Induced Mastitis.
Guo W, Liu B, Yin Y, Kan X, Gong Q, Li Y, Cao Y, Wang J, Xu D, Ma H, Fu S, Liu J
Frontiers in immunology 2019;10:287
Frontiers in immunology 2019;10:287
Administration of Akkermansia muciniphila Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice.
Bian X, Wu W, Yang L, Lv L, Wang Q, Li Y, Ye J, Fang D, Wu J, Jiang X, Shi D, Li L
Frontiers in microbiology 2019;10:2259
Frontiers in microbiology 2019;10:2259
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
Heydarian M, Yang T, Schweinlin M, Steinke M, Walles H, Rudel T, Kozjak-Pavlovic V
Frontiers in microbiology 2019;10:1740
Frontiers in microbiology 2019;10:1740
A Chinese Prescription Yu-Ping-Feng-San Administered in Remission Restores Bronchial Epithelial Barrier to Inhibit House Dust Mite-Induced Asthma Recurrence.
Bao K, Yuan W, Zhou Y, Chen Y, Yu X, Wang X, Jia Z, Yu X, Wang X, Yao L, Wang S, Xu Y, Zhang Y, Zheng J, Hong M
Frontiers in pharmacology 2019;10:1698
Frontiers in pharmacology 2019;10:1698
Cathelicidin-WA Facilitated Intestinal Fatty Acid Absorption Through Enhancing PPAR-γ Dependent Barrier Function.
Zong X, Cao X, Wang H, Xiao X, Wang Y, Lu Z
Frontiers in immunology 2019;10:1674
Frontiers in immunology 2019;10:1674
The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1.
Ott T, Kaufmann L, Granzow M, Hinderhofer K, Bartram CR, Theiß S, Seitz A, Paramasivam N, Schulz A, Moog U, Blum M, Evers CM
Frontiers in physiology 2019;10:134
Frontiers in physiology 2019;10:134
Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection.
Martins Gomes SF, Westermann AJ, Sauerwein T, Hertlein T, Förstner KU, Ohlsen K, Metzger M, Shusta EV, Kim BJ, Appelt-Menzel A, Schubert-Unkmeir A
Frontiers in microbiology 2019;10:1181
Frontiers in microbiology 2019;10:1181
Cilostazol ameliorates ischemia/reperfusion-induced tight junction disruption in brain endothelial cells by inhibiting endoplasmic reticulum stress.
Nan D, Jin H, Deng J, Yu W, Liu R, Sun W, Huang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10152-10164
Bletilla striata polysaccharides ameliorates lipopolysaccharide-induced injury in intestinal epithelial cells.
Luo L, Liu Y, Cai X, Wang Y, Xue J, Zhang J, Yang F
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2019 Sep-Oct;25(5):302-308
Regulatory effect of a Chinese herbal medicine formula on non-alcoholic fatty liver disease.
Yang JM, Sun Y, Wang M, Zhang XL, Zhang SJ, Gao YS, Chen L, Wu MY, Zhou L, Zhou YM, Wang Y, Zheng FJ, Li YH
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
World journal of gastroenterology 2019 Sep 14;25(34):5105-5119
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Li X, Mao M, Zhang Y, Yu K, Zhu W
Biomolecules 2019 Sep 13;9(9)
Biomolecules 2019 Sep 13;9(9)
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Chen Y, Chen JQ, Ge MM, Zhang Q, Wang XQ, Zhu JY, Xie CF, Li XT, Zhong CY, Han HY
The Journal of nutritional biochemistry 2019 Oct;72:108219
The Journal of nutritional biochemistry 2019 Oct;72:108219
Neuroprotective effect of Vanillin on hypoxic-ischemic brain damage in neonatal rats.
Lan XB, Wang Q, Yang JM, Ma L, Zhang WJ, Zheng P, Sun T, Niu JG, Liu N, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109196
Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility.
Zhang J, Yao D, Song Y, Pan Y, Zhu L, Bai Y, Xu Y, Zhang J, Shao C
Scientific reports 2019 Oct 23;9(1):15221
Scientific reports 2019 Oct 23;9(1):15221
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Wang X, Adegoke EO, Ma M, Huang F, Zhang H, Adeniran SO, Zheng P, Zhang G
Theriogenology 2019 Oct 15;138:84-93
Theriogenology 2019 Oct 15;138:84-93
Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis.
Ren MT, Gu ML, Zhou XX, Yu MS, Pan HH, Ji F, Ding CY
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
World journal of gastroenterology 2019 Oct 14;25(38):5800-5813
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z
Toxicology letters 2019 Nov;316:109-118
Toxicology letters 2019 Nov;316:109-118
Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro.
Li CX, Wang XQ, Cheng FF, Yan X, Luo J, Wang QG
Neural regeneration research 2019 Nov;14(11):1941-1949
Neural regeneration research 2019 Nov;14(11):1941-1949
The effects of c-Src kinase on EMT signaling pathway in human lens epithelial cells associated with lens diseases.
Li X, Wang F, Ren M, Du M, Zhou J
BMC ophthalmology 2019 Nov 8;19(1):219
BMC ophthalmology 2019 Nov 8;19(1):219
An in vitro intestinal platform with a self-sustaining oxygen gradient to study the human gut/microbiome interface.
Kim R, Attayek PJ, Wang Y, Furtado KL, Tamayo R, Sims CE, Allbritton NL
Biofabrication 2019 Nov 6;12(1):015006
Biofabrication 2019 Nov 6;12(1):015006
The protective effect of selenium from heat stress-induced porcine small intestinal epithelial cell line (IPEC-J2) injury is associated with regulation expression of selenoproteins.
Tang J, Cao L, Jia G, Liu G, Chen X, Tian G, Cai J, Shang H, Zhao H
The British journal of nutrition 2019 Nov 28;122(10):1081-1090
The British journal of nutrition 2019 Nov 28;122(10):1081-1090
Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora.
Wang J, Zhang C, Guo C, Li X
International journal of molecular sciences 2019 Nov 15;20(22)
International journal of molecular sciences 2019 Nov 15;20(22)
Chitosan coating of zein-carboxymethylated short-chain amylose nanocomposites improves oral bioavailability of insulin in vitro and in vivo.
Ji N, Hong Y, Gu Z, Cheng L, Li Z, Li C
Journal of controlled release : official journal of the Controlled Release Society 2019 Nov 10;313:1-13
Journal of controlled release : official journal of the Controlled Release Society 2019 Nov 10;313:1-13
GABA attenuates ETEC-induced intestinal epithelial cell apoptosis involving GABA(A)R signaling and the AMPK-autophagy pathway.
Xia Y, Chen S, Zhao Y, Chen S, Huang R, Zhu G, Yin Y, Ren W, Deng J
Food & function 2019 Nov 1;10(11):7509-7522
Food & function 2019 Nov 1;10(11):7509-7522
TIMM50 promotes tumor progression via ERK signaling and predicts poor prognosis of non-small cell lung cancer patients.
Zhang X, Han S, Zhou H, Cai L, Li J, Liu N, Liu Y, Wang L, Fan C, Li A, Miao Y
Molecular carcinogenesis 2019 May;58(5):767-776
Molecular carcinogenesis 2019 May;58(5):767-776
Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway.
Yin M, Shen Z, Yang L, Zheng W, Song H
International journal of molecular medicine 2019 May;43(5):2086-2102
International journal of molecular medicine 2019 May;43(5):2086-2102
Activation of SIRT1 ameliorates LPS-induced lung injury in mice via decreasing endothelial tight junction permeability.
Fu C, Hao S, Xu X, Zhou J, Liu Z, Lu H, Wang L, Jin W, Li S
Acta pharmacologica Sinica 2019 May;40(5):630-641
Acta pharmacologica Sinica 2019 May;40(5):630-641
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Propofol Protects Lung Endothelial Barrier Function by Suppression of High-Mobility Group Box 1 (HMGB1) Release and Mitochondrial Oxidative Damage Catalyzed by HMGB1.
Feng Z, Wang JW, Wang Y, Dong WW, Xu ZF
Medical science monitor : international medical journal of experimental and clinical research 2019 May 1;25:3199-3211
Medical science monitor : international medical journal of experimental and clinical research 2019 May 1;25:3199-3211
Magnolol exhibits anti-inflammatory and neuroprotective effects in a rat model of intracerebral haemorrhage.
Zhou F, Jiang Z, Yang B, Hu Z
Brain, behavior, and immunity 2019 Mar;77:161-167
Brain, behavior, and immunity 2019 Mar;77:161-167
Epidermal growth factor treatment has protective effects on the integrity of the blood-brain barrier against cerebral ischemia injury in bEnd3 cells.
Yang S, Jin H, Zhao ZG
Experimental and therapeutic medicine 2019 Mar;17(3):2397-2402
Experimental and therapeutic medicine 2019 Mar;17(3):2397-2402
Cold-inducible RNA-binding protein as a novel target to alleviate blood-brain barrier damage induced by cardiopulmonary bypass.
Liu M, Li Y, Liu Y, Yan S, Liu G, Zhang Q, Ji B
The Journal of thoracic and cardiovascular surgery 2019 Mar;157(3):986-996.e5
The Journal of thoracic and cardiovascular surgery 2019 Mar;157(3):986-996.e5
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Liu X, Dong H, Huang B, Miao H, Xu Z, Yuan Y, Qiu F, Chen J, Zhang H, Liu Z, Quan X, Zhu L, Zhang Z
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Ethyl pyruvate protects against Salmonella intestinal infection in mice through down-regulation of pro-inflammatory factors and inhibition of TLR4/MAPK pathway.
Dong N, Xu X, Xue C, Wang C, Li X, Shan A, Xu L, Li D
International immunopharmacology 2019 Jun;71:155-163
International immunopharmacology 2019 Jun;71:155-163
Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells.
Adegoke EO, Adeniran SO, Zeng Y, Wang X, Wang H, Wang C, Zhang H, Zheng P, Zhang G
Journal of applied toxicology : JAT 2019 Jun;39(6):832-843
Journal of applied toxicology : JAT 2019 Jun;39(6):832-843
ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling.
Zhu D, Zhou J, Zhao J, Jiang G, Zhang X, Zhang Y, Dong M
Journal of cellular physiology 2019 Jun;234(6):8899-8907
Journal of cellular physiology 2019 Jun;234(6):8899-8907
The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis.
Scheiber IF, Wu Y, Morgan SE, Zhao N
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
The Journal of biological chemistry 2019 Jun 7;294(23):9147-9160
Effects of MCRS1 on proliferation, migration, invasion, and epithelial mesenchymal transition of gastric cancer cells by interacting with Pkmyt1 protein kinase.
Wang XM, Li QY, Ren LL, Liu YM, Wang TS, Mu TC, Fu S, Liu C, Xiao JY
Cellular signalling 2019 Jul;59:171-181
Cellular signalling 2019 Jul;59:171-181
Connexin43 dephosphorylation at serine 282 is associated with connexin43-mediated cardiomyocyte apoptosis.
Yang Y, Yan X, Xue J, Zheng Y, Chen M, Sun Z, Liu T, Wang C, You H, Luo D
Cell death and differentiation 2019 Jul;26(7):1332-1345
Cell death and differentiation 2019 Jul;26(7):1332-1345
Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity.
Li H, Fan C, Feng C, Wu Y, Lu H, He P, Yang X, Zhu F, Qi Q, Gao Y, Zuo J, Tang W
British journal of pharmacology 2019 Jul;176(13):2209-2226
British journal of pharmacology 2019 Jul;176(13):2209-2226
HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration.
Sun S, Cai B, Li Y, Su W, Zhao X, Gong B, Li Z, Zhang X, Wu Y, Chen C, Tsang SH, Yang J, Li X
Aging 2019 Jul 7;11(13):4323-4337
Aging 2019 Jul 7;11(13):4323-4337
Geniposide protects against hypoxia/reperfusion-induced blood-brain barrier impairment by increasing tight junction protein expression and decreasing inflammation, oxidative stress, and apoptosis in an in vitro system.
Li C, Wang X, Cheng F, Du X, Yan J, Zhai C, Mu J, Wang Q
European journal of pharmacology 2019 Jul 5;854:224-231
European journal of pharmacology 2019 Jul 5;854:224-231
The protective effect of protopanaxatriol-type saponin on intestinal health in antibiotic-treated mice.
Zhang M, Zhao J, Deng J, Duan Z, Zhu C, Fan D
Food & function 2019 Jul 17;10(7):4124-4133
Food & function 2019 Jul 17;10(7):4124-4133
Downregulation of DAPK1 promotes the stemness of cancer stem cells and EMT process by activating ZEB1 in colorectal cancer.
Yuan W, Ji J, Shu Y, Chen J, Liu S, Wu L, Zhou Z, Liu Z, Tang Q, Zhang X, Shu X
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
Journal of molecular medicine (Berlin, Germany) 2019 Jan;97(1):89-102
S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA(2) phosphorylation.
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, Jin L, Li S
Cellular signalling 2019 Jan;53:151-161
Cellular signalling 2019 Jan;53:151-161
Nuclear factor I/B promotes colorectal cancer cell proliferation, epithelial-mesenchymal transition and 5-fluorouracil resistance.
Liu Z, Chen J, Yuan W, Ruan H, Shu Y, Ji J, Wu L, Tang Q, Zhou Z, Zhang X, Cheng Y, He S, Shu X
Cancer science 2019 Jan;110(1):86-98
Cancer science 2019 Jan;110(1):86-98
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, Zhong C, Li X
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Cao W, Wang C, Chin Y, Chen X, Gao Y, Yuan S, Xue C, Wang Y, Tang Q
Food & function 2019 Jan 22;10(1):277-288
Food & function 2019 Jan 22;10(1):277-288
Response of Colonic Mucosa-Associated Microbiota Composition, Mucosal Immune Homeostasis, and Barrier Function to Early Life Galactooligosaccharides Intervention in Suckling Piglets.
Wang J, Tian S, Yu H, Wang J, Zhu W
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Journal of agricultural and food chemistry 2019 Jan 16;67(2):578-588
Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension.
Wang J, Yu M, Xu J, Cheng Y, Li X, Wei G, Wang H, Kong H, Xie W
Journal of biomedical science 2019 Jan 12;26(1):6
Journal of biomedical science 2019 Jan 12;26(1):6
An increase of estrogen receptor α protein level regulates BDE-209-mediated blood-testis barrier disruption during spermatogenesis in F1 mice.
Zhai J, Geng X, Ding T, Li J, Tang J, Chen D, Cui L, Wang Q
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
Environmental science and pollution research international 2019 Feb;26(5):4801-4820
LncRNA CRNDE promotes the epithelial-mesenchymal transition of hepatocellular carcinoma cells via enhancing the Wnt/β-catenin signaling pathway.
Zhu L, Yang N, Du G, Li C, Liu G, Liu S, Xu Y, Di Y, Pan W, Li X
Journal of cellular biochemistry 2019 Feb;120(2):1156-1164
Journal of cellular biochemistry 2019 Feb;120(2):1156-1164
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Li J, Hao Y, Mao W, Xue X, Xu P, Liu L, Yuan J, Zhang D, Li N, Chen H, Zhao L, Sun Z, Luo J, Chen R, Zhao RC
Journal of hematology & oncology 2019 Feb 22;12(1):19
Journal of hematology & oncology 2019 Feb 22;12(1):19
Vanillin protects the blood-milk barrier and inhibits the inflammatory response in LPS-induced mastitis in mice.
Guo W, Liu B, Hu G, Kan X, Li Y, Gong Q, Xu D, Ma H, Cao Y, Huang B, Fu S, Liu J
Toxicology and applied pharmacology 2019 Feb 15;365:9-18
Toxicology and applied pharmacology 2019 Feb 15;365:9-18
Ezrin, a Membrane Cytoskeleton Cross-Linker Protein, as a Marker of Epithelial Damage in Asthma.
Jia M, Yan X, Jiang X, Wu Y, Xu J, Meng Y, Yang Y, Shan X, Zhang X, Mao S, Gu W, Pavlidis S, Barnes PJ, Adcock IM, Huang M, Yao X
American journal of respiratory and critical care medicine 2019 Feb 15;199(4):496-507
American journal of respiratory and critical care medicine 2019 Feb 15;199(4):496-507
Activation of G protein-coupled estrogen receptor protects intestine from ischemia/reperfusion injury in mice by protecting the crypt cell proliferation.
Chai S, Liu K, Feng W, Liu T, Wang Q, Zhou R, Chen S, Wang L, Chen G, Ming T, Zhao J, Liu C, Xue B
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
Clinical science (London, England : 1979) 2019 Feb 14;133(3):449-464
Lipoprotein receptor-related protein 6 is required to maintain intercalated disk integrity.
Wang X, Zou Y, Li Y, Chen Z, Yin C, Wang Y, Zhang L, Wu J, Yang C, Zhang G, Zou Y, Gong H
Genes to cells : devoted to molecular & cellular mechanisms 2019 Dec;24(12):789-800
Genes to cells : devoted to molecular & cellular mechanisms 2019 Dec;24(12):789-800
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Fan X, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota.
Wu M, Li P, An Y, Ren J, Yan D, Cui J, Li D, Li M, Wang M, Zhong G
Pharmacological research 2019 Dec;150:104489
Pharmacological research 2019 Dec;150:104489
Protective effects of acarbose against vascular endothelial dysfunction through inhibiting Nox4/NLRP3 inflammasome pathway in diabetic rats.
Li XX, Ling SK, Hu MY, Ma Y, Li Y, Huang PL
Free radical biology & medicine 2019 Dec;145:175-186
Free radical biology & medicine 2019 Dec;145:175-186
The role of sphingosine 1-phosphate receptors on retinal pigment epithelial cells barrier function and angiogenic effects.
Terao R, Honjo M, Totsuka K, Miwa Y, Kurihara T, Aihara M
Prostaglandins & other lipid mediators 2019 Dec;145:106365
Prostaglandins & other lipid mediators 2019 Dec;145:106365
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
Jiang YP, Yang JM, Ye RJ, Liu N, Zhang WJ, Ma L, Zheng P, Niu JG, Liu P, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109474
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, Wang Q, Ni Z, Mou S, Dai H, Pang H, Gu L
Cell death & disease 2019 Dec 4;10(12):915
Cell death & disease 2019 Dec 4;10(12):915
Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway.
You M, Miao Z, Pan Y, Hu F
European journal of pharmacology 2019 Dec 15;865:172736
European journal of pharmacology 2019 Dec 15;865:172736
Oral delivery of a Lactococcus lactis strain secreting bovine lactoferricin-lactoferrampin alleviates the development of acute colitis in mice.
Song L, Xie W, Liu Z, Guo D, Zhao D, Qiao X, Wang L, Zhou H, Cui W, Jiang Y, Li Y, Xu Y, Tang L
Applied microbiology and biotechnology 2019 Aug;103(15):6169-6186
Applied microbiology and biotechnology 2019 Aug;103(15):6169-6186
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Sun L, Zhang W, Li Z, Li M, Guo J, Wang H, Wang X
Scientific reports 2019 Aug 8;9(1):11510
Scientific reports 2019 Aug 8;9(1):11510
Protein phosphatase 2A modulates podocyte maturation and glomerular functional integrity in mice.
Zhu X, Ye Y, Xu C, Gao C, Zhang Y, Zhou J, Lin W, Mao J
Cell communication and signaling : CCS 2019 Aug 6;17(1):91
Cell communication and signaling : CCS 2019 Aug 6;17(1):91
Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells.
Kim BJ, McDonagh MA, Deng L, Gastfriend BD, Schubert-Unkmeir A, Doran KS, Shusta EV
Fluids and barriers of the CNS 2019 Aug 22;16(1):26
Fluids and barriers of the CNS 2019 Aug 22;16(1):26
Estrogen receptor β inhibits breast cancer cells migration and invasion through CLDN6-mediated autophagy.
Song P, Li Y, Dong Y, Liang Y, Qu H, Qi D, Lu Y, Jin X, Guo Y, Jia Y, Wang X, Xu W, Quan C
Journal of experimental & clinical cancer research : CR 2019 Aug 14;38(1):354
Journal of experimental & clinical cancer research : CR 2019 Aug 14;38(1):354
Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices.
Frost TS, Jiang L, Lynch RM, Zohar Y
Micromachines 2019 Aug 13;10(8)
Micromachines 2019 Aug 13;10(8)
Glucagon-like peptide-1 receptor activation alleviates lipopolysaccharide-induced acute lung injury in mice via maintenance of endothelial barrier function.
Xu J, Wei G, Wang J, Zhu J, Yu M, Zeng X, Wang H, Xie W, Kong H
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
Laboratory investigation; a journal of technical methods and pathology 2019 Apr;99(4):577-587
Roseburia intestinalis inhibits oncostatin M and maintains tight junction integrity in a murine model of acute experimental colitis.
Tan B, Luo W, Shen Z, Xiao M, Wu S, Meng X, Wu X, Yang Z, Tian L, Wang X
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
Scandinavian journal of gastroenterology 2019 Apr;54(4):432-440
C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.
Li X, Dong M, Zhou J, Zhu D, Zhao J, Sheng W
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Molecular and cellular biochemistry 2019 Apr;454(1-2):87-95
Butyrate Protects Mice Against Methionine-Choline-Deficient Diet-Induced Non-alcoholic Steatohepatitis by Improving Gut Barrier Function, Attenuating Inflammation and Reducing Endotoxin Levels.
Ye J, Lv L, Wu W, Li Y, Shi D, Fang D, Guo F, Jiang H, Yan R, Ye W, Li L
Frontiers in microbiology 2018;9:1967
Frontiers in microbiology 2018;9:1967
Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis.
Huang Y, He J, Liang H, Hu K, Jiang S, Yang L, Mei S, Zhu X, Yu J, Kijlstra A, Yang P, Hou S
Frontiers in immunology 2018;9:1713
Frontiers in immunology 2018;9:1713
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Wang Y, Kim R, Gunasekara DB, Reed MI, DiSalvo M, Nguyen DL, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Effects of Dietary Serine Supplementation on Intestinal Integrity, Inflammation and Oxidative Status in Early-Weaned Piglets.
Zhou X, Zhang Y, Wu X, Wan D, Yin Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):993-1002
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):993-1002
Clostridium Tyrobutyricum Protect Intestinal Barrier Function from LPS-Induced Apoptosis via P38/JNK Signaling Pathway in IPEC-J2 Cells.
Xiao Z, Liu L, Tao W, Pei X, Wang G, Wang M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):1779-1792
The Protective Mechanism of CAY10683 on Intestinal Mucosal Barrier in Acute Liver Failure through LPS/TLR4/MyD88 Pathway.
Wang Y, Chen H, Chen Q, Jiao FZ, Zhang WB, Gong ZJ
Mediators of inflammation 2018;2018:7859601
Mediators of inflammation 2018;2018:7859601
Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases.
Chen X, Liu R, Liu X, Xu C, Wang X
BioMed research international 2018;2018:7207268
BioMed research international 2018;2018:7207268
Volatile Oil of Amomum villosum Inhibits Nonalcoholic Fatty Liver Disease via the Gut-Liver Axis.
Lu S, Zhang T, Gu W, Yang X, Lu J, Zhao R, Yu J
BioMed research international 2018;2018:3589874
BioMed research international 2018;2018:3589874
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity.
Yu M, Wang Q, Ma Y, Li L, Yu K, Zhang Z, Chen G, Li X, Xiao W, Xu P, Yang H
International journal of biological sciences 2018;14(1):69-77
International journal of biological sciences 2018;14(1):69-77
A novel SWIM domain protein ZSWIM5 inhibits the malignant progression of non-small-cell lung cancer.
Xu K, Liu B, Ma Y, Xu B, Xing X
Cancer management and research 2018;10:3245-3254
Cancer management and research 2018;10:3245-3254
ZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling.
Liu B, Xing X, Li X, Guo Q, Xu T, Xu K
Cancer management and research 2018;10:3159-3168
Cancer management and research 2018;10:3159-3168
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Ma J, Yin G, Lu Z, Xie P, Zhou H, Liu J, Yu L
Phytotherapy research : PTR 2018 Sep;32(9):1770-1783
Phytotherapy research : PTR 2018 Sep;32(9):1770-1783
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Jia Z, Wang X, Wang X, Wei P, Li L, Wu P, Hong M
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Bletilla striata polysaccharide has a protective effect on intestinal epithelial barrier disruption in TAA-induced cirrhotic rats.
Luo L, Zhou Z, Xue J, Wang Y, Zhang J, Cai X, Liu Y, Yang F
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
Experimental and therapeutic medicine 2018 Sep;16(3):1715-1722
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Li M, Wen Y, Zhang R, Xie F, Zhang G, Qin X
Brain research bulletin 2018 Sep;142:54-62
Brain research bulletin 2018 Sep;142:54-62
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway.
Adegoke EO, Wang C, Machebe NS, Wang X, Wang H, Adeniran SO, Zhang H, Zheng P, Zhang G
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Environmental toxicology and pharmacology 2018 Oct;63:115-126
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Adegoke EO, Wang X, Wang H, Wang C, Zhang H, Zhang G
Biological trace element research 2018 Oct;185(2):332-343
Biological trace element research 2018 Oct;185(2):332-343
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition.
Wang W, Hu Y, Yang C, Zhu S, Wang X, Zhang Z, Deng H
Molecular & cellular proteomics : MCP 2018 Oct;17(10):2005-2017
Molecular & cellular proteomics : MCP 2018 Oct;17(10):2005-2017
Fluoride altered rat's blood testis barrier by affecting the F-actin via IL-1α.
He X, Sun Z, Manthari RK, Wu P, Wang J
Chemosphere 2018 Nov;211:826-833
Chemosphere 2018 Nov;211:826-833
Effects of berberine on tumor growth and intestinal permeability in HCT116 tumor-bearing mice using polyamines as targets.
Wu YY, Li TM, Zang LQ, Liu B, Wang GX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1447-1453
miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer.
Yan M, Yang X, Shen R, Wu C, Wang H, Ye Q, Yang P, Zhang L, Chen M, Wan B, Zhang Q, Xia S, Lu X, Shao G, Zhou X, Yu J, Shao Q
Cell death & disease 2018 Nov 8;9(11):1123
Cell death & disease 2018 Nov 8;9(11):1123
Hemopexin reduces blood-brain barrier injury and protects synaptic plasticity in cerebral ischemic rats by promoting EPCs through the HO-1 pathway.
Yang Y, Dong B, Lu J, Wang G, Yu Y
Brain research 2018 Nov 15;1699:177-185
Brain research 2018 Nov 15;1699:177-185
Autocrine transforming growth factor-β/activin A-Smad signaling induces hepatic progenitor cells undergoing partial epithelial-mesenchymal transition states.
Wu Y, Ding ZY, Jin GN, Xiong YX, Yu B, Sun YM, Wang W, Liang HF, Zhang B, Chen XP
Biochimie 2018 May;148:87-98
Biochimie 2018 May;148:87-98
Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice.
Wang X, Zhang X, Hu L, Li H
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
Reproductive biology and endocrinology : RB&E 2018 May 31;16(1):55
YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD.
Yu M, Chen Y, Li X, Yang R, Zhang L, Huangfu L, Zheng N, Zhao X, Lv L, Hong Y, Liang H, Shan H
Cell death & disease 2018 May 1;9(5):464
Cell death & disease 2018 May 1;9(5):464
Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood-Brain Barrier Permeability During Early Reperfusion in Stroke.
Zhang S, An Q, Wang T, Gao S, Zhou G
Neuroscience 2018 May 1;377:126-137
Neuroscience 2018 May 1;377:126-137
Aryl hydrocarbon receptor activation maintained the intestinal epithelial barrier function through Notch1 dependent signaling pathway.
Liu Z, Li L, Chen W, Wang Q, Xiao W, Ma Y, Sheng B, Li X, Sun L, Yu M, Yang H
International journal of molecular medicine 2018 Mar;41(3):1560-1572
International journal of molecular medicine 2018 Mar;41(3):1560-1572
Zinc finger protein 668 suppresses non-small cell lung cancer invasion and migration by downregulating Snail and upregulating E-cadherin and zonula occludens-1.
Zhang X, Jiang G, Wu J, Zhou H, Zhang Y, Miao Y, Feng Y, Yu J
Oncology letters 2018 Mar;15(3):3806-3813
Oncology letters 2018 Mar;15(3):3806-3813
ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD(+)-Mediated Epithelial-Mesenchymal Transition.
Wang W, Hu Y, Wang X, Wang Q, Deng H
Cell chemical biology 2018 Mar 15;25(3):255-261.e4
Cell chemical biology 2018 Mar 15;25(3):255-261.e4
miR-381-3p knockdown improves intestinal epithelial proliferation and barrier function after intestinal ischemia/reperfusion injury by targeting nurr1.
Liu L, Yao J, Li Z, Zu G, Feng D, Li Y, Qasim W, Zhang S, Li T, Zeng H, Tian X
Cell death & disease 2018 Mar 14;9(3):411
Cell death & disease 2018 Mar 14;9(3):411
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
2-(2-Benzofuranyl)-2-Imidazoline Mediates Neuroprotection by Regulating the Neurovascular Unit Integrity in a Rat Model of Focal Cerebral Ischemia.
Zhang Z, Zhang L, Chen J, Cao Y, Qu M, Lin X, Han Z, Ji X
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jun;27(6):1481-1489
Effects of chronic noise exposure on the microbiome-gut-brain axis in senescence-accelerated prone mice: implications for Alzheimer's disease.
Cui B, Su D, Li W, She X, Zhang M, Wang R, Zhai Q
Journal of neuroinflammation 2018 Jun 22;15(1):190
Journal of neuroinflammation 2018 Jun 22;15(1):190
Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis.
Ye JZ, Li YT, Wu WR, Shi D, Fang DQ, Yang LY, Bian XY, Wu JJ, Wang Q, Jiang XW, Peng CG, Ye WC, Xia PC, Li LJ
World journal of gastroenterology 2018 Jun 21;24(23):2468-2481
World journal of gastroenterology 2018 Jun 21;24(23):2468-2481
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Chen X, Hong M, Yang Q, Wang J
Journal of neuroinflammation 2018 Jun 21;15(1):188
Journal of neuroinflammation 2018 Jun 21;15(1):188
Tail Vein Infusion of Adipose-Derived Mesenchymal Stem Cell Alleviated Inflammatory Response and Improved Blood Brain Barrier Condition by Suppressing Endoplasmic Reticulum Stress in a Middle Cerebral Artery Occlusion Rat Model.
Chi L, Huang Y, Mao Y, Wu K, Zhang L, Nan G
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 11;24:3946-3957
Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 11;24:3946-3957
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice.
Crotty Alexander LE, Drummond CA, Hepokoski M, Mathew D, Moshensky A, Willeford A, Das S, Singh P, Yong Z, Lee JH, Vega K, Du A, Shin J, Javier C, Tian J, Brown JH, Breen EC
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
American journal of physiology. Regulatory, integrative and comparative physiology 2018 Jun 1;314(6):R834-R847
Lipopolysaccharide Induces Subacute Cerebral Microhemorrhages with Involvement of Nitric Oxide Synthase in Rats.
Zeng J, Zhào H, Liu Z, Zhang W, Huang Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jul;27(7):1905-1913
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2018 Jul;27(7):1905-1913
A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model.
Kanwal S, Joseph TP, Owusu L, Xiaomeng R, Meiqi L, Yi X
Nutrients 2018 Jul 31;10(8)
Nutrients 2018 Jul 31;10(8)
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Liu M, Yang J, Zhang Y, Zhou Z, Cui X, Zhang L, Fung KM, Zheng W, Allard FD, Yee EU, Ding K, Wu H, Liang Z, Zheng L, Fernandez-Zapico ME, Li YP, Bronze MS, Morris KT, Postier RG, Houchen CW, Yang J, Li M
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway.
Zou Y, Ma L, Zhao Y, Zhang S, Zhou C, Cai Y
International journal of molecular medicine 2018 Jan;41(1):430-438
International journal of molecular medicine 2018 Jan;41(1):430-438
A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats.
Zhang DD, Jin C, Zhang YT, Gan XD, Zou MJ, Wang YY, Fu WL, Xu T, Xing WW, Xia WR, Xu DG
Journal of neuroinflammation 2018 Jan 15;15(1):16
Journal of neuroinflammation 2018 Jan 15;15(1):16
An ECV304 monoculture model for permeability assessment of blood-brain barrier.
Yang S, Jin H, Zhao Z
Neurological research 2018 Feb;40(2):117-121
Neurological research 2018 Feb;40(2):117-121
A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells.
Tian H, Xu JY, Tian Y, Cao Y, Lian C, Ou Q, Wu B, Jin C, Gao F, Wang J, Zhang J, Zhang J, Li W, Lu L, Xu GT
Experimental eye research 2018 Dec;177:160-172
Experimental eye research 2018 Dec;177:160-172
DNase-1 Treatment Exerts Protective Effects in a Rat Model of Intestinal Ischemia-Reperfusion Injury.
Wang S, Xie T, Sun S, Wang K, Liu B, Wu X, Ding W
Scientific reports 2018 Dec 12;8(1):17788
Scientific reports 2018 Dec 12;8(1):17788
Paracellular tightness and the functional expression of efflux transporters P-gp and BCRP in bEnd3 cells.
Yang S, Jin H, Zhao Z
Neurological research 2018 Aug;40(8):644-649
Neurological research 2018 Aug;40(8):644-649
Metformin Protects against LPS-Induced Intestinal Barrier Dysfunction by Activating AMPK Pathway.
Wu W, Wang S, Liu Q, Shan T, Wang Y
Molecular pharmaceutics 2018 Aug 6;15(8):3272-3284
Molecular pharmaceutics 2018 Aug 6;15(8):3272-3284
Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury.
Main BS, Villapol S, Sloley SS, Barton DJ, Parsadanian M, Agbaegbu C, Stefos K, McCann MS, Washington PM, Rodriguez OC, Burns MP
Molecular neurodegeneration 2018 Apr 4;13(1):17
Molecular neurodegeneration 2018 Apr 4;13(1):17
Potential Orphan Drug Therapy of Intravesical Liposomal Onabotulinumtoxin-A for Ketamine-Induced Cystitis by Mucosal Protection and Anti-inflammation in a Rat Model.
Lee WC, Su CH, Tain YL, Tsai CN, Yu CC, Chuang YC
Scientific reports 2018 Apr 11;8(1):5795
Scientific reports 2018 Apr 11;8(1):5795
Volatile Oil from Amomi Fructus Attenuates 5-Fluorouracil-Induced Intestinal Mucositis.
Zhang T, Lu SH, Bi Q, Liang L, Wang YF, Yang XX, Gu W, Yu J
Frontiers in pharmacology 2017;8:786
Frontiers in pharmacology 2017;8:786
Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense.
Zeng Q, He X, Puthiyakunnon S, Xiao H, Gong Z, Boddu S, Chen L, Tian H, Huang SH, Cao H
Frontiers in microbiology 2017;8:1798
Frontiers in microbiology 2017;8:1798
Protection of Tong-Qiao-Huo-Xue Decoction against Cerebral Ischemic Injury through Reduction Blood-Brain Barrier Permeability.
Li L, Wang N, Jin Q, Wu Q, Liu Y, Wang Y
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Chemical & pharmaceutical bulletin 2017;65(11):1004-1010
Calycosin Suppresses Epithelial Derived Initiative Key Factors and Maintains Epithelial Barrier in Allergic Inflammation via TLR4 Mediated NF-κB Pathway.
Tao Y, Wang Y, Wang X, Wang C, Bao K, Ji L, Jiang G, Hong M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(3):1106-1119
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(3):1106-1119
Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier.
Yang S, Mei S, Jin H, Zhu B, Tian Y, Huo J, Cui X, Guo A, Zhao Z
PloS one 2017;12(10):e0187017
PloS one 2017;12(10):e0187017
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibition.
Li W, Li X, Liu S, Yang W, Pan F, Yang XY, Du B, Qin L, Pan Y
International journal of nanomedicine 2017;12:3509-3520
International journal of nanomedicine 2017;12:3509-3520
Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients.
Zhang X, Zhou H, Cai L, Fan C, Liu Y, Wang L, Li Q, Miao Y
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Molecular carcinogenesis 2017 Sep;56(9):2058-2065
Lasp1 promotes malignant phenotype of non-small-cell lung cancer via inducing phosphorylation of FAK-AKT pathway.
Zhang X, Liu Y, Fan C, Wang L, Li A, Zhou H, Cai L, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Sep 26;8(43):75102-75113
Oncotarget 2017 Sep 26;8(43):75102-75113
TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
Zhang X, Zhang Y, Miao Y, Zhou H, Jiang G, Wang E
Oncotarget 2017 Sep 19;8(41):70685-70694
Oncotarget 2017 Sep 19;8(41):70685-70694
Role of macrophage migration inhibitory factor (MIF) in the effects of oxidative stress on human retinal pigment epithelial cells.
Ko JA, Sotani Y, Ibrahim DG, Kiuchi Y
Cell biochemistry and function 2017 Oct;35(7):426-432
Cell biochemistry and function 2017 Oct;35(7):426-432
The Protective Effect of Heme Oxygenase-1 against Intestinal Barrier Dysfunction in Cholestatic Liver Injury Is Associated with NF-κB Inhibition.
Zhang L, Zhang Z, Liu B, Jin Y, Tian Y, Xin Y, Duan Z
Molecular medicine (Cambridge, Mass.) 2017 Oct;23:215-224
Molecular medicine (Cambridge, Mass.) 2017 Oct;23:215-224
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway.
Sheng W, Chen C, Dong M, Wang G, Zhou J, Song H, Li Y, Zhang J, Ding S
Cell death & disease 2017 Oct 26;8(10):e3147
Cell death & disease 2017 Oct 26;8(10):e3147
Administration of alpha-ketoglutarate improves epithelial restitution under stress injury in early-weaning piglets.
He L, Zhou X, Huang N, Li H, Cui Z, Tian J, Jiang Q, Liu S, Wu J, Li T, Yao K, Yin Y
Oncotarget 2017 Nov 3;8(54):91965-91978
Oncotarget 2017 Nov 3;8(54):91965-91978
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model.
Han J, Li JH, Bai G, Shen GS, Chen J, Liu JN, Wang S, Liu XJ
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
World journal of gastroenterology 2017 Mar 28;23(12):2175-2184
ZNF452 facilitates tumor proliferation and invasion via activating AKT-GSK3β signaling pathway and predicts poor prognosis of non-small cell lung cancer patients.
Zhang X, Zhou H, Zhang Y, Cai L, Jiang G, Li A, Miao Y, Li Q, Qiu X, Wang E
Oncotarget 2017 Jun 13;8(24):38863-38875
Oncotarget 2017 Jun 13;8(24):38863-38875
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Wang Y, DiSalvo M, Gunasekara DB, Dutton J, Proctor A, Lebhar MS, Williamson IA, Speer J, Howard RL, Smiddy NM, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Alex3 suppresses non-small cell lung cancer invasion via AKT/Slug/E-cadherin pathway.
Du J, Zhang X, Zhou H, Miao Y, Han Y, Han Q, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317701441
Small Interfering RNA Targeting Dickkopf-1 Contributes to Neuroprotection After Intracerebral Hemorrhage in Rats.
Li Z, Chen X, Zhang X, Ren X, Chen X, Cao J, Zang W, Liu X, Guo F
Journal of molecular neuroscience : MN 2017 Feb;61(2):279-288
Journal of molecular neuroscience : MN 2017 Feb;61(2):279-288
Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Zhang X, Jiang G, Sun M, Zhou H, Miao Y, Liang M, Wang E, Zhang Y
Oncotarget 2017 Feb 21;8(8):13357-13366
Oncotarget 2017 Feb 21;8(8):13357-13366
Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.
Zhang X, Cai L, Zhou H, Liu Y, Fan C, Wang L, Li A, Miao Y, Li Q, Qiu X, Wang E
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
Molecular carcinogenesis 2017 Dec;56(12):2558-2565
Targeted deletion of Aqp4 promotes the formation of astrocytic gap junctions.
Katoozi S, Skauli N, Rahmani S, Camassa LMA, Boldt HB, Ottersen OP, Amiry-Moghaddam M
Brain structure & function 2017 Dec;222(9):3959-3972
Brain structure & function 2017 Dec;222(9):3959-3972
Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.
Appelt-Menzel A, Cubukova A, Günther K, Edenhofer F, Piontek J, Krause G, Stüber T, Walles H, Neuhaus W, Metzger M
Stem cell reports 2017 Apr 11;8(4):894-906
Stem cell reports 2017 Apr 11;8(4):894-906
CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation.
Ramena G, Yin Y, Yu Y, Walia V, Elble RC
PloS one 2016;11(3):e0147489
PloS one 2016;11(3):e0147489
Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier.
Yang R, Liu W, Miao L, Yang X, Fu J, Dou B, Cai A, Zong X, Tan C, Chen H, Wang X
Oncotarget 2016 Sep 27;7(39):63839-63855
Oncotarget 2016 Sep 27;7(39):63839-63855
Phenotype transformation of immortalized NCM460 colon epithelial cell line by TGF-β1 is associated with chromosome instability.
Huang C, Wen B
Molecular biology reports 2016 Oct;43(10):1069-78
Molecular biology reports 2016 Oct;43(10):1069-78
A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells.
Kong J, Luo Y, Jin D, An F, Zhang W, Liu L, Li J, Fang S, Li X, Yang X, Lin B, Liu T
Oncotarget 2016 Nov 29;7(48):78421-78432
Oncotarget 2016 Nov 29;7(48):78421-78432
SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.
Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W
JCI insight 2016 Nov 17;1(19):e86934
JCI insight 2016 Nov 17;1(19):e86934
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Suzuki R, Nakamura Y, Chiba S, Mizuno T, Abe K, Horii Y, Nagashima H, Tanita T, Yamauchi K
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Pulmonary pharmacology & therapeutics 2016 Jun;38:27-35
Knockout of BRD7 results in impaired spermatogenesis and male infertility.
Wang H, Zhao R, Guo C, Jiang S, Yang J, Xu Y, Liu Y, Fan L, Xiong W, Ma J, Peng S, Zeng Z, Zhou Y, Li X, Li Z, Li X, Schmitt DC, Tan M, Li G, Zhou M
Scientific reports 2016 Feb 16;6:21776
Scientific reports 2016 Feb 16;6:21776
bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury.
Wang ZG, Cheng Y, Yu XC, Ye LB, Xia QH, Johnson NR, Wei X, Chen DQ, Cao G, Fu XB, Li XK, Zhang HY, Xiao J
Molecular neurobiology 2016 Dec;53(10):7298-7311
Molecular neurobiology 2016 Dec;53(10):7298-7311
Polysaccharides from Acanthopanax senticosus enhances intestinal integrity through inhibiting TLR4/NF-κB signaling pathways in lipopolysaccharide-challenged mice.
Han J, Liu L, Yu N, Chen J, Liu B, Yang D, Shen G
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
Animal science journal = Nihon chikusan Gakkaiho 2016 Aug;87(8):1011-8
A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway.
Sun L, Xu C, Chen G, Yu M, Yang S, Qiu Y, Peng K, Wang W, Xiao W, Yang H
International journal of biological sciences 2015;11(6):664-71
International journal of biological sciences 2015;11(6):664-71
Naturally Occurring Stilbenoid TSG Reverses Non-Alcoholic Fatty Liver Diseases via Gut-Liver Axis.
Lin P, Lu J, Wang Y, Gu W, Yu J, Zhao R
PloS one 2015;10(10):e0140346
PloS one 2015;10(10):e0140346
Cytosolic TMEM88 promotes triple-negative breast cancer by interacting with Dvl.
Yu X, Zhang X, Zhang Y, Jiang G, Mao X, Jin F
Oncotarget 2015 Sep 22;6(28):25034-45
Oncotarget 2015 Sep 22;6(28):25034-45
Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism.
Dong WW, Liu YJ, Lv Z, Mao YF, Wang YW, Zhu XY, Jiang L
Free radical biology & medicine 2015 Nov;88(Pt B):404-416
Free radical biology & medicine 2015 Nov;88(Pt B):404-416
Par-3 modulates intestinal epithelial barrier function through regulating intracellular trafficking of occludin and myosin light chain phosphorylation.
Yu M, Yang S, Qiu Y, Chen G, Wang W, Xu C, Cai W, Sun L, Xiao W, Yang H
Journal of gastroenterology 2015 Nov;50(11):1103-13
Journal of gastroenterology 2015 Nov;50(11):1103-13
The multi-targeted tyrosine kinase inhibitor vandetanib plays a bifunctional role in non-small cell lung cancer cells.
Zhou Y, Zhang Y, Zou H, Cai N, Chen X, Xu L, Kong X, Liu P
Scientific reports 2015 Feb 27;5:8629
Scientific reports 2015 Feb 27;5:8629
C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.
Zhang X, Miao Y, Yu X, Zhang Y, Jiang G, Liu Y, Yu J, Han Q, Zhao H, Wang E
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Aug;36(8):5979-85
miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
Miao L, Xiong X, Lin Y, Cheng Y, Lu J, Zhang J, Cheng N
Oncology letters 2014 Mar;7(3):658-662
Oncology letters 2014 Mar;7(3):658-662
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke.
Yang F, Wang Z, Wei X, Han H, Meng X, Zhang Y, Shi W, Li F, Xin T, Pang Q, Yi F
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014 Apr;34(4):660-7
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Ning Q, Liu C, Hou L, Meng M, Zhang X, Luo M, Shao S, Zuo X, Zhao X
PloS one 2013;8(6):e65217
PloS one 2013;8(6):e65217
Keratinocyte growth factor pretreatment prevents radiation-induced intestinal damage in a mouse model.
Cai Y, Wang W, Liang H, Sun L, Teitelbaum DH, Yang H
Scandinavian journal of gastroenterology 2013 Apr;48(4):419-26
Scandinavian journal of gastroenterology 2013 Apr;48(4):419-26
Increased epithelial permeability is the primary cause for bicarbonate loss in inflamed murine colon.
Juric M, Xiao F, Amasheh S, May O, Wahl K, Bantel H, Manns MP, Seidler U, Bachmann O
Inflammatory bowel diseases 2013 Apr;19(5):904-11
Inflammatory bowel diseases 2013 Apr;19(5):904-11
Keratinocyte growth factor improves epithelial structure and function in a mouse model of intestinal ischemia/reperfusion.
Cai Y, Wang W, Liang H, Sun L, Teitelbaum DH, Yang H
PloS one 2012;7(9):e44772
PloS one 2012;7(9):e44772
Deletion of aquaporin-4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier.
Eilert-Olsen M, Haj-Yasein NN, Vindedal GF, Enger R, Gundersen GA, Hoddevik EH, Petersen PH, Haug FM, Skare Ø, Adams ME, Froehner SC, Burkhardt JM, Thoren AE, Nagelhus EA
Glia 2012 Mar;60(3):432-40
Glia 2012 Mar;60(3):432-40
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 21773-1-AP(ZO1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21773-1-AP(ZO1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21773-1-AP(ZO1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ZO-1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ZO-1. This antibody recognizes human antigen. The ZO-1 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
