Antibody data
- Antibody Data
- Antigen structure
- References [111]
- Comments [0]
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- Product number
- 66452-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- ZO-1 antibody
- Antibody type
- Monoclonal
- Description
- ZO-1 antibody (Cat. #66452-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, Canine and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Canine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1G4A1
- Vial size
- 20ul, 150ul
Submitted references Geometrically Constrained Growth Factor Concentration Favors Enrichment of Goblet Cells and Mucus Formation.
Clostridium perfringens Type A Isolated from Intestinal Contents of Alpaca.
Lycium Barbarum Polysaccharide Attenuates Staphylococcus aureus-Induced Mastitis via the Gut Microbiota-Derived Indole-3-Propionic Acid/AhR-IL-22-STAT3 Axis.
Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosis.
Iridoids derived from Valeriana jatamansi Jones alleviates neuroinflammation and blood spinal cord barrier permeability after spinal cord injury by activating the Nrf2/HO-1 signaling pathway.
Multi-omics reveal the neuroprotective mechanisms of Xinshubao tablet against scopolamine-induced cognitive dysfunction in mice.
Molecular mechanisms of the anchang group prescription in treating radiation enteritis: network pharmacology analysis and experimental evidence.
Claudin-1 impairs blood-brain barrier by downregulating endothelial junctional proteins in traumatic brain injury.
Association between AHR in EGCs and IBS-D patients: the indole pathway of tryptophan metabolism.
Effect of four traditional Chinese medicine monomers on mechanical barrier damage and inflammation response of IPEC-J2 cells caused by soybean 7S globulin.
EMB is essential for enteric nervous system development mediated by PI3K signaling.
Butyrate enhances recovery of chemotherapy-induced oral mucositis by enhancing tight junction protein expression and inhibiting inflammatory responses.
NDR1/2 kinases regulate cell polarization and cell motility through Cdc42 GTPase and Pard3 signaling in mammalian cells.
Promotion of angiogenesis in cerebral infarction by Tongqiao Huoxue Decoction through activation of glycolysis.
KLK1 as an Epithelial-Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R-Mediated Fibroblast Phenotypic Transition.
Patients with inflammatory bowel disease exhibit increased susceptibility to HCoV-NL63.
Astragalus mongholicus polysaccharides alleviate insulin resistance through modulation of PI3K/AKT, TLR4/NF-kB signaling pathway and microbiota in rats with Type 2 Diabetes Mellitus.
Sedanolide alleviates DSS-induced colitis by modulating the intestinal FXR-SMPD3 pathway in mice.
Preparation, characterization, and stability of selenium nanoparticles decorated with Mori Fructus polysaccharide and its protective effects in bisphenol A-induced Sertoli cells.
Expression of recombination antimicrobial protein PIL22-PBD-2 in Pichia pastoris and verification of its biological function in vitro.
Sodium butyrate inhibits activation of ROS/NF-κB/NLRP3 signaling pathway and angiogenesis in human retinal microvascular endothelial cells.
Crip2 affects vascular development by fine-tuning endothelial cell aggregation and proliferation.
Enteroendocrine Cells Regulate Intestinal Barrier Permeability.
Photobiomodulation mitigates blood-brain barrier disruption in APP/PS1 mouse model of Alzheimer's disease by activating the AMPK pathway.
The Protective Effect of Low-dose Nicotine on Ischemia Stroke by Maintaining the Integrity of the Blood-Brain Barrier.
Luteolin Alleviates Ulcerative Colitis in Mice by Modulating Gut Microbiota and Plasma Metabolism.
The Role of TRPV1/CGRP Pathway Activated by Prevotella melaninogenica in Pathogenesis of Oral Lichen Planus.
Luteolin modulates macrophage phenotypic switching via the AMPK-PPARγ pathway to alleviate ulcerative colitis in mice.
Dietary Capsaicin Exacerbates Gut Microbiota Dysbiosis and Mental Disorders in Type 1 Diabetes Mice.
Pectin-Zein-IPA nanoparticles promote functional recovery and alleviate neuroinflammation after spinal cord injury.
Vasoactive intestinal peptide reduces ocular hypertension by regulating tight junction of trabecular meshwork through Rab13/PKA signalling complex.
Redirecting the route: Monocyte-mediated delivery of oHSV-1 across a human BBB-on-chip model.
Lenvatinib promotes hepatocellular carcinoma pyroptosis by regulating GSDME palmitoylation.
Gut microbiota-regulated unconjugated bilirubin metabolism drives renal calcium oxalate crystal deposition.
Liberation of galactose from lactose by gut microbial β-galactosidase prevents uterine bacterial infection.
Biomass fuel induces neuroinflammation and neurodegeneration via the astrocyte-microglia IL-17A/IL-17RA pathway.
Vitamin D enhances the therapeutic effect of TNF-α antibodies through lipid metabolism in overweight IBD patients.
Characterization and optimization of variability in a human colonic epithelium culture model.
SIRT2 Promotes NLRP3-Mediated Microglia Pyroptosis and Neuroinflammation via FOXO3a Pathway After Subarachnoid Hemorrhage.
Lipopolysaccharide in Bile Promotes the Neutrophil Extracellular Traps-Induced Gallstone Formation by Activating the Gallbladder Immune Barrier.
MicroRNA-522-3p promotes brain metastasis in non-small cell lung cancer by targeting Tensin 1 and modulating blood-brain barrier permeability.
Mechanistic study of fructus aurantii (Quzhou origin) in regulating ileal reg3g in the treatment for NASH.
Mind the Particle Rigidity: Blooms the Bioavailability via Rapidly Crossing the Mucus Layer and Alters the Intracellular Fate of Curcumin.
Ferritinophagy is involved in hexavalent chromium-induced ferroptosis in Sertoli cells.
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Helicobacter pylori CagA Promotes the Formation of Gallstones by Increasing the Permeability of Gallbladder Epithelial Cells.
miRNA Expression Analysis of IPEC-J2 Cells Damaged by Soybean 7S Globulin Reveals ssc-miR-221-5p as the Factor Alleviating Cell Damage.
Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes.
Xylooligosaccharides ameliorate insulin resistance by increasing Akkermansia muciniphila and improving intestinal barrier dysfunction in gestational diabetes mellitus mice.
Octreotide attenuates intestinal barrier damage by maintaining basal autophagy in Caco2 cells.
Revealing the Mechanism of NLRP3 Inflammatory Pathway Activation through K(+) Efflux Induced by PLO via Signal Point Mutations.
Rutin prevents pyroptosis and M1 microglia via Nrf2/Mac-1/caspase-1-mediated inflammasome axis to improve POCD.
An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain.
Ginsenoside Rg2 alleviates astrocyte inflammation and ameliorates the permeability of the Alzheimer's disease related blood-brain barrier.
AHR activation relieves deoxynivalenol-induced disruption of porcine intestinal epithelial barrier functions.
A Glucose-Responsive Hydrogel Inhibits Primary and Secondary BRB Injury for Retinal Microenvironment Remodeling in Diabetic Retinopathy.
Neuroprotection of rhubarb extract against cerebral ischaemia-reperfusion injury via the gut-brain axis pathway.
Intestinal Piezo1 aggravates intestinal barrier dysfunction during sepsis by mediating Ca(2+) influx.
The coumarin component isofraxidin targets the G-protein-coupled receptor S1PR1 to modulate IL-17 signaling and alleviate ulcerative colitis.
Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice.
Characterization and optimization of variability in a human colonic epithelium culture model.
Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier.
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis.
LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
Betaine-Based and Polyguanidine-Inserted Zwitterionic Micelle as a Promising Platform to Conquer the Intestinal Mucosal Barrier.
zwitterionic Pluronic analog-coated PLGA nanoparticles for oral insulin delivery.
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition.
Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases.
Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma.
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
RNF114 facilitates the proliferation, stemness, and metastasis of colorectal cancer.
Chronic Stress That Changed Intestinal Permeability and Induced Inflammation Was Restored by Estrogen.
TAK-242 Ameliorates Hepatic Fibrosis by Regulating the Liver-Gut Axis.
Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota.
Exploration of the potential mechanism of Baicalin for hepatic fibrosis based on network pharmacology, gut microbiota, and experimental validation.
Effects of glycolysis and polyamine predation on intestinal epithelial barrier in colorectal cancer.
Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage.
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
New mechanism for mesenchymal stem cell microvesicle to restore lung permeability: intracellular S1P signaling pathway independent of S1P receptor-1.
Nicotinamide N-Methyltransferase Remodeled Cell Metabolism and Aggravated Proinflammatory Responses by Activating STAT3/IL1β/PGE(2) Pathway.
Polystyrene nanoparticles enhance the adverse effects of di-(2-ethylhexyl) phthalate on male reproductive system in mice.
Prenatal exposure to titanium dioxide nanoparticles induces persistent neurobehavioral impairments in maternal mice that is associated with microbiota-gut-brain axis.
pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance "One Stone Four Birds" Effect of Rhein on Ulcerative Colitis.
Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis.
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer.
Lactobacillus rhamnosus Ameliorates Multi-Drug-Resistant Bacillus cereus-Induced Cell Damage through Inhibition of NLRP3 Inflammasomes and Apoptosis in Bovine Endometritis.
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Gut microbiota dysbiosis induced by polychlorinated biphenyl 126 contributes to increased brain proinflammatory cytokines: Landscapes from the gut-brain axis and fecal microbiota transplantation.
Role of Autotaxin in High Glucose-Induced Human ARPE-19 Cells.
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy.
Coronary Collateral Microcirculation Reserve Becomes Vestigial with Aging.
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2.
Chitosan-chelated zinc modulates ileal microbiota, ileal microbial metabolites, and intestinal function in weaned piglets challenged with Escherichia coli K88.
Effects of intragastric administration of La(2)O(3) nanoparticles on mouse testes.
oprC Impairs Host Defense by Increasing the Quorum-Sensing-Mediated Virulence of Pseudomonas aeruginosa.
An electrochemical biosensor for the detection of epithelial-mesenchymal transition.
Alteration of fecal tryptophan metabolism correlates with shifted microbiota and may be involved in pathogenesis of colorectal cancer.
Mice with pre-existing tumors are vulnerable to postoperative cognitive dysfunction.
LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial-Mesenchymal Transition.
Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function.
High-fat diet promotes experimental colitis by inducing oxidative stress in the colon.
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
Villegas-Novoa C, Wang Y, Wang H, Jan I, Sims CE, Allbritton NL
ACS biomaterials science & engineering 2026 May 11;12(5):2700-2713
ACS biomaterials science & engineering 2026 May 11;12(5):2700-2713
Clostridium perfringens Type A Isolated from Intestinal Contents of Alpaca.
Ren H, Jia Q, Gao S, Yang H, Zhang S, Fan R
Microorganisms 2026 Jan 12;14(1)
Microorganisms 2026 Jan 12;14(1)
Lycium Barbarum Polysaccharide Attenuates Staphylococcus aureus-Induced Mastitis via the Gut Microbiota-Derived Indole-3-Propionic Acid/AhR-IL-22-STAT3 Axis.
Li K, Ran X, Ding H, Han J, Zhang L, Wang X, Guo W, Li Y, Fu S, Bi J
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12038-12053
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12038-12053
Sulforaphane alleviates membranous nephropathy by inhibiting oxidative stress-associated podocyte pyroptosis.
Lv D, Chu L, Du Y, Li C, Bao N, Su Y, Wang G, Zheng Y, Yu Y
Iranian journal of basic medical sciences 2025;28(2):237-244
Iranian journal of basic medical sciences 2025;28(2):237-244
Iridoids derived from Valeriana jatamansi Jones alleviates neuroinflammation and blood spinal cord barrier permeability after spinal cord injury by activating the Nrf2/HO-1 signaling pathway.
He Y, Lu J, Pang R, Ding L, Wang Y, Xiao H, Cheng C, Luo Y, Hu X, Wang W
Frontiers in pharmacology 2025;16:1597719
Frontiers in pharmacology 2025;16:1597719
Multi-omics reveal the neuroprotective mechanisms of Xinshubao tablet against scopolamine-induced cognitive dysfunction in mice.
Yang Z, Zhang FR, Ren L, Bai JM, Wang SC, Li XY, Yang HJ, Xiao HH
Frontiers in pharmacology 2025;16:1596728
Frontiers in pharmacology 2025;16:1596728
Molecular mechanisms of the anchang group prescription in treating radiation enteritis: network pharmacology analysis and experimental evidence.
Liang W, Li B, Sun Y, Jia D, Hu T, Huang R, Liu Z, Yang H, Chen B, Yin X, He X, Sun Y
Frontiers in pharmacology 2025;16:1524925
Frontiers in pharmacology 2025;16:1524925
Claudin-1 impairs blood-brain barrier by downregulating endothelial junctional proteins in traumatic brain injury.
Gowrikumar S, Tarudji A, McDonald BZ, Balusa SS, Kievit FM, Dhawan P
Tissue barriers 2025;13(4):2470482
Tissue barriers 2025;13(4):2470482
Association between AHR in EGCs and IBS-D patients: the indole pathway of tryptophan metabolism.
Wang L, Zhang Y, Ran Y, Li L, Mei L, Ye F, Sun Y, Wang T, Quan X, Shi H, Dai F
Frontiers in nutrition 2025;12:1566595
Frontiers in nutrition 2025;12:1566595
Effect of four traditional Chinese medicine monomers on mechanical barrier damage and inflammation response of IPEC-J2 cells caused by soybean 7S globulin.
Deng Y, Wu X, Wan Y, Deng J, Deng H
Frontiers in veterinary science 2025;12:1548866
Frontiers in veterinary science 2025;12:1548866
EMB is essential for enteric nervous system development mediated by PI3K signaling.
Li Z, Zhuansun D, Meng X, Yang H, Xiao J, Chen Y, Wang J, Yu X, Li Z, You J, Chen X, Feng C, Wu L, Chu X, Duan W, Wang K, Li Z, Tou J, Yu L, Tang W, Liu Y, Jiang X, Ren H, Yu M, Yin Q, Liu X, Xu Z, Wu D, Jiao C, Yu D, Wu X, Zhu T, Yang J, Xiang L, Wang J, Wang Q, Zhou B, Wang D, Chen K, Mao H, Wang B, Zhan J, Wang CY, Zeng W, Chen F, Xiong B, Feng J
Genome medicine 2025 Sep 25;17(1):102
Genome medicine 2025 Sep 25;17(1):102
Butyrate enhances recovery of chemotherapy-induced oral mucositis by enhancing tight junction protein expression and inhibiting inflammatory responses.
Zeng J, Tan Z, Zhang K, Han Q, Ou S, Wang Z, Liu J, Wang F, Huang Y, Wu L
Medicina oral, patologia oral y cirugia bucal 2025 Sep 1;30(5):e657-e663
Medicina oral, patologia oral y cirugia bucal 2025 Sep 1;30(5):e657-e663
NDR1/2 kinases regulate cell polarization and cell motility through Cdc42 GTPase and Pard3 signaling in mammalian cells.
Gu J, Marjanovic J, Tomic-Canic M, Zhang F, Verde F
bioRxiv : the preprint server for biology 2025 Oct 31;
bioRxiv : the preprint server for biology 2025 Oct 31;
Promotion of angiogenesis in cerebral infarction by Tongqiao Huoxue Decoction through activation of glycolysis.
Li X, Zhang R, Li G, Liu Z, Han H, Dong P
Metabolic brain disease 2025 Oct 11;40(7):288
Metabolic brain disease 2025 Oct 11;40(7):288
KLK1 as an Epithelial-Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R-Mediated Fibroblast Phenotypic Transition.
Zhou L, Wang M, Liu S, Gu L, Liu S, Du Q, Zhang T, Ma Y, Zhao L, Wang J, Xu Q, Ling T, Cheng H, Chen H, Sun Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e07063
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(42):e07063
Patients with inflammatory bowel disease exhibit increased susceptibility to HCoV-NL63.
Ning T, Liu N, Jiang Q, Zhang N, Zhu S
Gut pathogens 2025 Nov 23;17(1):101
Gut pathogens 2025 Nov 23;17(1):101
Astragalus mongholicus polysaccharides alleviate insulin resistance through modulation of PI3K/AKT, TLR4/NF-kB signaling pathway and microbiota in rats with Type 2 Diabetes Mellitus.
Yuan H, Xu G, Liu J, Yan Y, Zhao S, Cai F, Yu X, Wang Y, Li M
Journal of traditional and complementary medicine 2025 May;15(3):274-285
Journal of traditional and complementary medicine 2025 May;15(3):274-285
Sedanolide alleviates DSS-induced colitis by modulating the intestinal FXR-SMPD3 pathway in mice.
Li S, Zhuge A, Chen H, Han S, Shen J, Wang K, Xia J, Xia H, Jiang S, Wu Y, Li L
Journal of advanced research 2025 Mar;69:413-426
Journal of advanced research 2025 Mar;69:413-426
Preparation, characterization, and stability of selenium nanoparticles decorated with Mori Fructus polysaccharide and its protective effects in bisphenol A-induced Sertoli cells.
Cao M, Qian Y, Sun Z, Liu S, Zheng R, Zhao L, Chen G
International journal of biological macromolecules 2025 Mar;294:139463
International journal of biological macromolecules 2025 Mar;294:139463
Expression of recombination antimicrobial protein PIL22-PBD-2 in Pichia pastoris and verification of its biological function in vitro.
Li X, Qiu P, Yue M, Zhang Y, Lei C, Wang J, Chen X, Qi X
Veterinary research 2025 Mar 7;56(1):52
Veterinary research 2025 Mar 7;56(1):52
Sodium butyrate inhibits activation of ROS/NF-κB/NLRP3 signaling pathway and angiogenesis in human retinal microvascular endothelial cells.
Cao X, Di Y, Tian YJ, Huang XB, Zhou Y, Zhang DM, Song Y
International ophthalmology 2025 Mar 18;45(1):108
International ophthalmology 2025 Mar 18;45(1):108
Crip2 affects vascular development by fine-tuning endothelial cell aggregation and proliferation.
Yang S, Zhang X, Li X, Li H
Cellular and molecular life sciences : CMLS 2025 Mar 13;82(1):110
Cellular and molecular life sciences : CMLS 2025 Mar 13;82(1):110
Enteroendocrine Cells Regulate Intestinal Barrier Permeability.
Nwako JG, Patel SD, Roach TJ, Gupte SR, Williams SG, Riedman AM, McCauley HA
bioRxiv : the preprint server for biology 2025 Mar 12;
bioRxiv : the preprint server for biology 2025 Mar 12;
Photobiomodulation mitigates blood-brain barrier disruption in APP/PS1 mouse model of Alzheimer's disease by activating the AMPK pathway.
Ma C, Ye Y, Shi X, Li N, Mu Z, Tan T, Yin H, Dai J, Liu Y, Chen H
Alzheimer's research & therapy 2025 Jun 23;17(1):141
Alzheimer's research & therapy 2025 Jun 23;17(1):141
The Protective Effect of Low-dose Nicotine on Ischemia Stroke by Maintaining the Integrity of the Blood-Brain Barrier.
Pang Q, Yan X, Chen Z, Yun L, Qian J, Dong Z, Wang M, Deng W, Fu Y, Hai T, Chen Z, Rong X
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2025 Jul 22;27(8):1420-1429
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2025 Jul 22;27(8):1420-1429
Luteolin Alleviates Ulcerative Colitis in Mice by Modulating Gut Microbiota and Plasma Metabolism.
Yang S, Duan H, Yan Z, Xue C, Niu T, Cheng W, Zhang Y, Zhao X, Hu J, Zhang L
Nutrients 2025 Jan 7;17(2)
Nutrients 2025 Jan 7;17(2)
The Role of TRPV1/CGRP Pathway Activated by Prevotella melaninogenica in Pathogenesis of Oral Lichen Planus.
Xu P, Shao R, Zhu P, Fei J, He Y
International journal of molecular sciences 2025 Jan 14;26(2)
International journal of molecular sciences 2025 Jan 14;26(2)
Luteolin modulates macrophage phenotypic switching via the AMPK-PPARγ pathway to alleviate ulcerative colitis in mice.
Yang S, Duan H, Zeng J, Yan Z, Niu T, Ma X, Zhang Y, Hu J, Zhang L, Zhao X
Journal of ethnopharmacology 2025 Jan 13;339:119157
Journal of ethnopharmacology 2025 Jan 13;339:119157
Dietary Capsaicin Exacerbates Gut Microbiota Dysbiosis and Mental Disorders in Type 1 Diabetes Mice.
Zhang X, Hu H, Zhang Y, Hu S, Lu J, Peng W, Luo D
Nutrients 2025 Feb 6;17(3)
Nutrients 2025 Feb 6;17(3)
Pectin-Zein-IPA nanoparticles promote functional recovery and alleviate neuroinflammation after spinal cord injury.
Chen X, Wang B, Al Mamun A, Du K, Wang S, Hu Q, Chen X, Lu Y, Du A, Wu Y, Shao J, Wang S, Jiang C, Zhou K, Hu S, Xiao J
Journal of nanobiotechnology 2025 Feb 28;23(1):152
Journal of nanobiotechnology 2025 Feb 28;23(1):152
Vasoactive intestinal peptide reduces ocular hypertension by regulating tight junction of trabecular meshwork through Rab13/PKA signalling complex.
Chen L, Yan X, Luo Z, Cheng Y, Li M
Annals of medicine 2025 Dec;57(1):2534527
Annals of medicine 2025 Dec;57(1):2534527
Redirecting the route: Monocyte-mediated delivery of oHSV-1 across a human BBB-on-chip model.
Micheli S, Reale A, Rossetto A, Parolin C, Mammano F, Calistri A, Cimetta E
Materials today. Bio 2025 Dec;35:102458
Materials today. Bio 2025 Dec;35:102458
Lenvatinib promotes hepatocellular carcinoma pyroptosis by regulating GSDME palmitoylation.
Yuan Y, Wang MR, Ding Y, Lin Y, Xu TT, He XX, Li PY
Cancer biology & therapy 2025 Dec;26(1):2532217
Cancer biology & therapy 2025 Dec;26(1):2532217
Gut microbiota-regulated unconjugated bilirubin metabolism drives renal calcium oxalate crystal deposition.
Li S, Wu W, Zhou Y, Zhang S, Wei D, Zhu M, Ying X, Sun X, Liu H, Zhu W, Tang D, Jiao R, Zeng G, Duan X, Liu J, Wu W
Gut microbes 2025 Dec;17(1):2546158
Gut microbes 2025 Dec;17(1):2546158
Liberation of galactose from lactose by gut microbial β-galactosidase prevents uterine bacterial infection.
Cai J, He Y, Qu L, Liu J, Xie X, Cao Y
The ISME journal 2025 Aug 20;
The ISME journal 2025 Aug 20;
Biomass fuel induces neuroinflammation and neurodegeneration via the astrocyte-microglia IL-17A/IL-17RA pathway.
Liang F, Xu Z, Ding L, Zhu Z, Chen M, Shu H, Huang X, Su Z, Wang X, Xiao Y, Huang S, Mai D, Yi E, Xu P, Zhang W
Journal of hazardous materials 2025 Aug 15;494:138569
Journal of hazardous materials 2025 Aug 15;494:138569
Vitamin D enhances the therapeutic effect of TNF-α antibodies through lipid metabolism in overweight IBD patients.
Yu W, Huang P, Jin Y, Wu F, Zhang C, Jing L, Chen Y, Xu H, Xiong J, Zhang R, Zhao K, Li X
Cellular and molecular life sciences : CMLS 2025 Apr 26;82(1):176
Cellular and molecular life sciences : CMLS 2025 Apr 26;82(1):176
Characterization and optimization of variability in a human colonic epithelium culture model.
Pike CM, Zwarycz B, McQueen BE, Castillo M, Barron C, Morowitz JM, Levi JA, Phadke D, Balik-Meisner M, Mav D, Shah R, Cunningham Glasspoole DL, Laetham R, Thelin W, Bunger MK, Boazak EM
ALTEX 2024;41(3):425-438
ALTEX 2024;41(3):425-438
SIRT2 Promotes NLRP3-Mediated Microglia Pyroptosis and Neuroinflammation via FOXO3a Pathway After Subarachnoid Hemorrhage.
Sun JQ, Sheng B, Gao S, Liu XZ, Cui Y, Peng Z, Chen XX, Ding PF, Zhuang Z, Wu LY, Hang CH, Li W
Journal of inflammation research 2024;17:11679-11698
Journal of inflammation research 2024;17:11679-11698
Lipopolysaccharide in Bile Promotes the Neutrophil Extracellular Traps-Induced Gallstone Formation by Activating the Gallbladder Immune Barrier.
Yu J, Meng Z, Liu X, Zheng Y, Xue D, Hao C, Wang L
ImmunoTargets and therapy 2024;13:789-803
ImmunoTargets and therapy 2024;13:789-803
MicroRNA-522-3p promotes brain metastasis in non-small cell lung cancer by targeting Tensin 1 and modulating blood-brain barrier permeability.
Liu Q, Bao H, Zhang S, Li C, Sun G, Sun X, Fu T, Wang Y, Liang P
Experimental cell research 2024 Sep 1;442(1):114199
Experimental cell research 2024 Sep 1;442(1):114199
Mechanistic study of fructus aurantii (Quzhou origin) in regulating ileal reg3g in the treatment for NASH.
Yan J, Nie Y, Chen X, Ding M, Zhang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155924
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Oct;133:155924
Mind the Particle Rigidity: Blooms the Bioavailability via Rapidly Crossing the Mucus Layer and Alters the Intracellular Fate of Curcumin.
Yuan D, Niu Z, Zheng W, Zhao Q, Zhou F, Zhao M
ACS nano 2024 Oct 1;18(39):27026-27041
ACS nano 2024 Oct 1;18(39):27026-27041
Ferritinophagy is involved in hexavalent chromium-induced ferroptosis in Sertoli cells.
Zhuge R, Zhang L, Xue Q, Wang R, Xu J, Wang C, Meng C, Lu R, Yin F, Guo L
Toxicology and applied pharmacology 2024 Nov;492:117139
Toxicology and applied pharmacology 2024 Nov;492:117139
TIPE2 aggravates experimental colitis and disrupts intestinal epithelial barrier integrity by activating JAK2/STAT3/SOCS3 signal pathway.
Zeng L, Wang Y, Shen J, Wei X, Wu Y, Chi X, Zheng X, Yu X, Shi Y, Liu W
Experimental cell research 2024 Nov 1;443(1):114287
Experimental cell research 2024 Nov 1;443(1):114287
Helicobacter pylori CagA Promotes the Formation of Gallstones by Increasing the Permeability of Gallbladder Epithelial Cells.
Yu J, He Y, Yao W, Liu T, Liu X, Zheng Y, Hao C, Xue D
Helicobacter 2024 May-Jun;29(3):e13100
Helicobacter 2024 May-Jun;29(3):e13100
miRNA Expression Analysis of IPEC-J2 Cells Damaged by Soybean 7S Globulin Reveals ssc-miR-221-5p as the Factor Alleviating Cell Damage.
Deng H, Ye T, Deng Y, Cui Y, Guo H, Deng J
Journal of agricultural and food chemistry 2024 May 22;72(20):11694-11705
Journal of agricultural and food chemistry 2024 May 22;72(20):11694-11705
Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes.
Christofidou ED, Tomazou M, Voutouri C, Michael C, Stylianopoulos T, Spyrou GM, Strati K
Cell reports 2024 Mar 26;43(3):113859
Cell reports 2024 Mar 26;43(3):113859
Xylooligosaccharides ameliorate insulin resistance by increasing Akkermansia muciniphila and improving intestinal barrier dysfunction in gestational diabetes mellitus mice.
Yang J, Wang J, Wu W, Su C, Wu Y, Li Q
Food & function 2024 Mar 18;15(6):3122-3129
Food & function 2024 Mar 18;15(6):3122-3129
Octreotide attenuates intestinal barrier damage by maintaining basal autophagy in Caco2 cells.
Liu X, Zhou Y, Zhang Y, Cui X, Yang D, Li Y
Molecular medicine reports 2024 Jun;29(6)
Molecular medicine reports 2024 Jun;29(6)
Revealing the Mechanism of NLRP3 Inflammatory Pathway Activation through K(+) Efflux Induced by PLO via Signal Point Mutations.
Shan Q, Ma W, Li B, Li Q, Wang X, Li Y, Wang J, Zhu Y, Liu N
International journal of molecular sciences 2024 Jun 18;25(12)
International journal of molecular sciences 2024 Jun 18;25(12)
Rutin prevents pyroptosis and M1 microglia via Nrf2/Mac-1/caspase-1-mediated inflammasome axis to improve POCD.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Jin D, Xu L, Ge S
International immunopharmacology 2024 Jan 25;127:111290
International immunopharmacology 2024 Jan 25;127:111290
An Amino Acids and Dipeptide Injection Inhibits the TNF-α/HMGB1 Inflammatory Signaling Pathway to Reduce Pyroptosis and M1 Microglial Polarization in POCD Mice: the Gut to the Brain.
Ji Y, Ma Y, Ma Y, Wang Y, Zhao X, Xu L, Ge S
Molecular neurobiology 2024 Dec;61(12):10097-10114
Molecular neurobiology 2024 Dec;61(12):10097-10114
Ginsenoside Rg2 alleviates astrocyte inflammation and ameliorates the permeability of the Alzheimer's disease related blood-brain barrier.
Lu YW, Wang YJ, Wang Z, Ren S, Gong XJ, Hu JN, Zhang JT, Li W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156063
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156063
AHR activation relieves deoxynivalenol-induced disruption of porcine intestinal epithelial barrier functions.
Hu ZY, Yang SJ, Chang YH, Wang XQ, Liu RQ, Jiang FW, Chen MS, Wang JX, Liu S, Zhu HM, Shi YS, Zhao Y, Li JL
Journal of hazardous materials 2024 Dec 5;480:136095
Journal of hazardous materials 2024 Dec 5;480:136095
A Glucose-Responsive Hydrogel Inhibits Primary and Secondary BRB Injury for Retinal Microenvironment Remodeling in Diabetic Retinopathy.
Zhou Y, Zhao C, Shi Z, Heger Z, Jing H, Shi Z, Dou Y, Wang S, Qiu Z, Li N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(32):e2402368
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(32):e2402368
Neuroprotection of rhubarb extract against cerebral ischaemia-reperfusion injury via the gut-brain axis pathway.
Mao M, Cao X, Liang Y, Li Q, Chen S, Zhou L, Zhang Y, Guo Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155254
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155254
Intestinal Piezo1 aggravates intestinal barrier dysfunction during sepsis by mediating Ca(2+) influx.
Yan Z, Niu L, Wang S, Gao C, Pan S
Journal of translational medicine 2024 Apr 4;22(1):332
Journal of translational medicine 2024 Apr 4;22(1):332
The coumarin component isofraxidin targets the G-protein-coupled receptor S1PR1 to modulate IL-17 signaling and alleviate ulcerative colitis.
Huang Y, Chen X, Liu X, Lin C, Wang Y
International immunopharmacology 2024 Apr 20;131:111814
International immunopharmacology 2024 Apr 20;131:111814
Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice.
Zhang Y, Liu Y, Zhang X, Yong VW, Xue M
Journal of inflammation research 2023;16:2535-2548
Journal of inflammation research 2023;16:2535-2548
Characterization and optimization of variability in a human colonic epithelium culture model.
Pike CM, Zwarycz B, McQueen BE, Castillo M, Barron C, Morowitz JM, Levi JA, Phadke D, Balik-Meisner M, Mav D, Shah R, Glasspoole DLC, Laetham R, Thelin W, Bunger MK, Boazak EM
bioRxiv : the preprint server for biology 2023 Sep 22;
bioRxiv : the preprint server for biology 2023 Sep 22;
Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
Yin J, Hu T, Xu L, Zhang L, Zhu J, Ye Y, Pang Z
International immunopharmacology 2023 Oct;123:110763
International immunopharmacology 2023 Oct;123:110763
Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier.
Mao A, Zhao W, Zhu Y, Kong F, Chen D, Si H, Xu C
Microorganisms 2023 Oct 24;11(11)
Microorganisms 2023 Oct 24;11(11)
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis.
Chen F, Wang S, Zeng C, Tang S, Gu H, Wang Z, Li J, Feng P, Zhang Y, Wang P, Wu Y, Shen H
Cellular and molecular life sciences : CMLS 2023 Oct 13;80(11):325
Cellular and molecular life sciences : CMLS 2023 Oct 13;80(11):325
LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
Hu G, Huang N, Zhang J, Zhang D, Wang S, Zhang Y, Wang L, Du Y, Kuang S, Ma K, Zhu H, Xu N, Liu M
Molecular carcinogenesis 2023 Nov;62(11):1659-1672
Molecular carcinogenesis 2023 Nov;62(11):1659-1672
Betaine-Based and Polyguanidine-Inserted Zwitterionic Micelle as a Promising Platform to Conquer the Intestinal Mucosal Barrier.
Liu K, Chen Y, Yang D, Cai Y, Yang Z, Jin J
ACS applied materials & interfaces 2023 Nov 8;15(44):51650-51662
ACS applied materials & interfaces 2023 Nov 8;15(44):51650-51662
zwitterionic Pluronic analog-coated PLGA nanoparticles for oral insulin delivery.
Liu K, Chen Y, Yang Z, Jin J
International journal of biological macromolecules 2023 May 1;236:123870
International journal of biological macromolecules 2023 May 1;236:123870
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
You B, Zhang T, Zhang W, Pei Y, Huang D, Lei Y, Zhang S, Qiu C, Zhang J, Gu Z, Cheng L, Chen J
iScience 2023 Mar 17;26(3):106151
iScience 2023 Mar 17;26(3):106151
Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition.
van Tienderen GS, Rosmark O, Lieshout R, Willemse J, de Weijer F, Elowsson Rendin L, Westergren-Thorsson G, Doukas M, Groot Koerkamp B, van Royen ME, van der Laan LJ, Verstegen MM
Acta biomaterialia 2023 Mar 1;158:115-131
Acta biomaterialia 2023 Mar 1;158:115-131
Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases.
Guo HH, Shen HR, Wang LL, Luo ZG, Zhang JL, Zhang HJ, Gao TL, Han YX, Jiang JD
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114754
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jul;163:114754
Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma.
Shen Y, Xu S, Ye C, Li Q, Chen R, Wu W, Jiang Q, Jia Y, Zhang X, Fan L, Fu W, Jiang M, Chen J, Timko MP, Zhao P, Ruan J
iScience 2023 Feb 17;26(2):106003
iScience 2023 Feb 17;26(2):106003
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
Gu K, Wang F, Sun W, Liu G, Jia G, Zhao H, Chen X, Wu C, Tian G, Cai J, Zhang R, Wang J
Animal biotechnology 2023 Dec;34(8):4069-4080
Animal biotechnology 2023 Dec;34(8):4069-4080
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
Zhu Y, Huang C, Zhang C, Zhou Y, Zhao E, Zhang Y, Pan X, Huang H, Liao W, Wang X
Nature communications 2023 Dec 8;14(1):8141
Nature communications 2023 Dec 8;14(1):8141
RNF114 facilitates the proliferation, stemness, and metastasis of colorectal cancer.
Liu SC, Gong LL, Huang FC, Xu N, Yang KX, Liu XH, Li WL
Pathology, research and practice 2023 Aug;248:154716
Pathology, research and practice 2023 Aug;248:154716
Chronic Stress That Changed Intestinal Permeability and Induced Inflammation Was Restored by Estrogen.
Li Y, Wan H, Ma R, Liu T, Chen Y, Dong Y
International journal of molecular sciences 2023 Aug 15;24(16)
International journal of molecular sciences 2023 Aug 15;24(16)
TAK-242 Ameliorates Hepatic Fibrosis by Regulating the Liver-Gut Axis.
Liu S, Wu J, Chen P, Mohammed SAD, Zhang J, Liu S
BioMed research international 2022;2022:4949148
BioMed research international 2022;2022:4949148
Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota.
Wang Z, You L, Ren Y, Zhu X, Mao X, Liang X, Wang T, Guo Y, Liu T, Xue J
Frontiers in physiology 2022;13:900961
Frontiers in physiology 2022;13:900961
Exploration of the potential mechanism of Baicalin for hepatic fibrosis based on network pharmacology, gut microbiota, and experimental validation.
Liu S, Chen P, Mohammed SAD, Li Z, Jiang X, Wu J, Liu S
Frontiers in microbiology 2022;13:1051100
Frontiers in microbiology 2022;13:1051100
Effects of glycolysis and polyamine predation on intestinal epithelial barrier in colorectal cancer.
Wang Y, He H, Chen J, Song Z, Pan X, Lan T, Wang G
Frontiers in oncology 2022;12:961257
Frontiers in oncology 2022;12:961257
Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage.
Feng D, Zhou J, Liu H, Wu X, Li F, Zhao J, Zhang Y, Wang L, Chao M, Wang Q, Qin H, Ge S, Liu Q, Zhang J, Qu Y
Science advances 2022 Sep 30;8(39):eabq2423
Science advances 2022 Sep 30;8(39):eabq2423
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
Zhu X, Chen Z, Wang L, Ou Q, Feng Z, Xiao H, Shen Q, Li Y, Jin C, Xu JY, Gao F, Wang J, Zhang J, Zhang J, Xu Z, Xu GT, Lu L, Tian H
Cell death & disease 2022 Sep 12;13(9):785
Cell death & disease 2022 Sep 12;13(9):785
New mechanism for mesenchymal stem cell microvesicle to restore lung permeability: intracellular S1P signaling pathway independent of S1P receptor-1.
Ye L, Song J, Zheng Y, Zhong M, Liu J, Zhu D, Hu S
Stem cell research & therapy 2022 Oct 8;13(1):496
Stem cell research & therapy 2022 Oct 8;13(1):496
Nicotinamide N-Methyltransferase Remodeled Cell Metabolism and Aggravated Proinflammatory Responses by Activating STAT3/IL1β/PGE(2) Pathway.
Yang C, Wang T, Zhu S, Zong Z, Luo C, Zhao Y, Liu J, Li T, Liu X, Liu C, Deng H
ACS omega 2022 Oct 25;7(42):37509-37519
ACS omega 2022 Oct 25;7(42):37509-37519
Polystyrene nanoparticles enhance the adverse effects of di-(2-ethylhexyl) phthalate on male reproductive system in mice.
Li D, Sun W, Jiang X, Yu Z, Xia Y, Cheng S, Mao L, Luo S, Tang S, Xu S, Zou Z, Chen C, Qiu J, Zhou L
Ecotoxicology and environmental safety 2022 Oct 15;245:114104
Ecotoxicology and environmental safety 2022 Oct 15;245:114104
Prenatal exposure to titanium dioxide nanoparticles induces persistent neurobehavioral impairments in maternal mice that is associated with microbiota-gut-brain axis.
Yang C, Xue J, Qin Q, Xia Y, Cheng S, Jiang X, Zhang S, Lu Z, Qin X, Zhang J, Mao L, Xu S, Qiu J, Zou Z, Chen C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Nov;169:113402
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Nov;169:113402
pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance "One Stone Four Birds" Effect of Rhein on Ulcerative Colitis.
Qi S, Luo R, Han X, Nie W, Ye N, Fu C, Gao F
ACS applied materials & interfaces 2022 Nov 16;14(45):50692-50709
ACS applied materials & interfaces 2022 Nov 16;14(45):50692-50709
Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis.
Lv D, Jiang S, Zhang M, Zhu X, Yang F, Wang H, Li S, Liu F, Zeng C, Qin W, Li L, Liu Z
Kidney diseases (Basel, Switzerland) 2022 Jul;8(4):308-318
Kidney diseases (Basel, Switzerland) 2022 Jul;8(4):308-318
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer.
Ji C, Zhang M, Hu J, Cao C, Gu Q, Liu Y, Li X, Xu D, Ying L, Yang Y, Gao H, Li J, Yu L
Cell death & disease 2022 Jul 1;13(7):577
Cell death & disease 2022 Jul 1;13(7):577
Lactobacillus rhamnosus Ameliorates Multi-Drug-Resistant Bacillus cereus-Induced Cell Damage through Inhibition of NLRP3 Inflammasomes and Apoptosis in Bovine Endometritis.
Liu N, Wang X, Shan Q, Xu L, Li Y, Chu B, Yang L, Wang J, Zhu Y
Microorganisms 2022 Jan 10;10(1)
Microorganisms 2022 Jan 10;10(1)
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Wang Y, Wang Q, Duan L, Li X, Yang W, Huang T, Kong M, Guan F, Ma S
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Hou Z, Ding Q, Li Y, Zhao Z, Yan F, Li Y, Wang X, Xu J, Chen W, Wu G, Ruan X, Zhao L
EBioMedicine 2022 Aug;82:104181
EBioMedicine 2022 Aug;82:104181
Gut microbiota dysbiosis induced by polychlorinated biphenyl 126 contributes to increased brain proinflammatory cytokines: Landscapes from the gut-brain axis and fecal microbiota transplantation.
Li T, Tian D, Lu M, Wang B, Li J, Xu B, Chen H, Wu S
Ecotoxicology and environmental safety 2022 Aug;241:113726
Ecotoxicology and environmental safety 2022 Aug;241:113726
Role of Autotaxin in High Glucose-Induced Human ARPE-19 Cells.
Liu Y, Yamagishi R, Honjo M, Kurano M, Yatomi Y, Igarashi K, Aihara M
International journal of molecular sciences 2022 Aug 16;23(16)
International journal of molecular sciences 2022 Aug 16;23(16)
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Xie C, Zhu J, Yang X, Huang C, Zhou L, Meng Z, Li X, Zhong C
Frontiers in cell and developmental biology 2021;9:645402
Frontiers in cell and developmental biology 2021;9:645402
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy.
Guo W, Li W, Su Y, Liu S, Kan X, Ran X, Cao Y, Fu S, Liu J
International journal of biological sciences 2021;17(15):4271-4284
International journal of biological sciences 2021;17(15):4271-4284
Coronary Collateral Microcirculation Reserve Becomes Vestigial with Aging.
Chen J, Liu X, Qin X, Liu Z, Zhu L, Quan X, Xu Z, Dong H, Zhang Z
Cardiology 2021;146(1):11-18
Cardiology 2021;146(1):11-18
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Zhang Z, Zheng Y, Niu Z, Zhang B, Wang C, Yao X, Peng H, Franca DN, Wang Y, Zhu Y, Su Y, Tang M, Jiang X, Ren H, He M, Wang Y, Gao L, Zhao P, Shi H, Chen Z, Wang X, Piacentini M, Bian X, Melino G, Liu L, Huang H, Sun Q
Cell death and differentiation 2021 Sep;28(9):2765-2777
Cell death and differentiation 2021 Sep;28(9):2765-2777
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Huang C, Ou R, Chen X, Zhang Y, Li J, Liang Y, Zhu X, Liu L, Li M, Lin D, Qiu J, Liu G, Zhang L, Wu Y, Tang H, Liu Y, Liang L, Ding Y, Liao W
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2.
Huang W, Xing Y, Zhu L, Zhuo J, Cai M
Experimental cell research 2021 Sep 1;406(1):112633
Experimental cell research 2021 Sep 1;406(1):112633
Chitosan-chelated zinc modulates ileal microbiota, ileal microbial metabolites, and intestinal function in weaned piglets challenged with Escherichia coli K88.
Hou G, Zhang M, Wang J, Zhu W
Applied microbiology and biotechnology 2021 Oct;105(19):7529-7544
Applied microbiology and biotechnology 2021 Oct;105(19):7529-7544
Effects of intragastric administration of La(2)O(3) nanoparticles on mouse testes.
Yuan L, Bai D, Meng L, Wang H, Sun Z, An T, Chen Z, Deng X, Zhang X
The Journal of toxicological sciences 2020;45(8):411-422
The Journal of toxicological sciences 2020;45(8):411-422
oprC Impairs Host Defense by Increasing the Quorum-Sensing-Mediated Virulence of Pseudomonas aeruginosa.
Gao P, Guo K, Pu Q, Wang Z, Lin P, Qin S, Khan N, Hur J, Liang H, Wu M
Frontiers in immunology 2020;11:1696
Frontiers in immunology 2020;11:1696
An electrochemical biosensor for the detection of epithelial-mesenchymal transition.
Du X, Zhang Z, Zheng X, Zhang H, Dong D, Zhang Z, Liu M, Zhou J
Nature communications 2020 Jan 10;11(1):192
Nature communications 2020 Jan 10;11(1):192
Alteration of fecal tryptophan metabolism correlates with shifted microbiota and may be involved in pathogenesis of colorectal cancer.
Sun XZ, Zhao DY, Zhou YC, Wang QQ, Qin G, Yao SK
World journal of gastroenterology 2020 Dec 7;26(45):7173-7190
World journal of gastroenterology 2020 Dec 7;26(45):7173-7190
Mice with pre-existing tumors are vulnerable to postoperative cognitive dysfunction.
Wu T, Wang X, Zhang R, Jiao Y, Yu W, Su D, Zhao Y, Tian J
Brain research 2020 Apr 1;1732:146650
Brain research 2020 Apr 1;1732:146650
LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial-Mesenchymal Transition.
Cai H, Li J, Zhang Y, Liao Y, Zhu Y, Wang C, Hou J
Frontiers in oncology 2019;9:1446
Frontiers in oncology 2019;9:1446
Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function.
Yuan Z, Yang L, Zhang X, Ji P, Hua Y, Wei Y
Frontiers in pharmacology 2019;10:1354
Frontiers in pharmacology 2019;10:1354
High-fat diet promotes experimental colitis by inducing oxidative stress in the colon.
Li X, Wei X, Sun Y, Du J, Li X, Xun Z, Li YC
American journal of physiology. Gastrointestinal and liver physiology 2019 Oct 1;317(4):G453-G462
American journal of physiology. Gastrointestinal and liver physiology 2019 Oct 1;317(4):G453-G462
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Liu X, Dong H, Huang B, Miao H, Xu Z, Yuan Y, Qiu F, Chen J, Zhang H, Liu Z, Quan X, Zhu L, Zhang Z
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
Han J, Guo D, Sun XY, Wang JM, Ouyang JM, Gui BS
Scientific reports 2019 Jul 8;9(1):9871
Scientific reports 2019 Jul 8;9(1):9871
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