Antibody data
- Antibody Data
- Antigen structure
- References [60]
- Comments [0]
- Validations [0]
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- Product number
- 66452-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- ZO-1 antibody
- Antibody type
- Monoclonal
- Description
- ZO-1 antibody (Cat. #66452-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, Canine and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Canine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1G4A1
- Vial size
- 20ul, 150ul
Submitted references miRNA Expression Analysis of IPEC-J2 Cells Damaged by Soybean 7S Globulin Reveals ssc-miR-221-5p as the Factor Alleviating Cell Damage.
Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes.
Octreotide attenuates intestinal barrier damage by maintaining basal autophagy in Caco2 cells.
Revealing the Mechanism of NLRP3 Inflammatory Pathway Activation through K(+) Efflux Induced by PLO via Signal Point Mutations.
Rutin prevents pyroptosis and M1 microglia via Nrf2/Mac-1/caspase-1-mediated inflammasome axis to improve POCD.
Neuroprotection of rhubarb extract against cerebral ischaemia-reperfusion injury via the gut-brain axis pathway.
Intestinal Piezo1 aggravates intestinal barrier dysfunction during sepsis by mediating Ca(2+) influx.
Sedanolide alleviates DSS-induced colitis by modulating the intestinal FXR-SMPD3 pathway in mice.
The coumarin component isofraxidin targets the G-protein-coupled receptor S1PR1 to modulate IL-17 signaling and alleviate ulcerative colitis.
Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice.
Characterization and optimization of variability in a human colonic epithelium culture model.
Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
Betaine-Based and Polyguanidine-Inserted Zwitterionic Micelle as a Promising Platform to Conquer the Intestinal Mucosal Barrier.
Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier.
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis.
LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
zwitterionic Pluronic analog-coated PLGA nanoparticles for oral insulin delivery.
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition.
Berberine is a potential alternative for metformin with good regulatory effect on lipids in treating metabolic diseases.
Proteomic and single-cell landscape reveals novel pathogenic mechanisms of HBV-infected intrahepatic cholangiocarcinoma.
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
RNF114 facilitates the proliferation, stemness, and metastasis of colorectal cancer.
Chronic Stress That Changed Intestinal Permeability and Induced Inflammation Was Restored by Estrogen.
TAK-242 Ameliorates Hepatic Fibrosis by Regulating the Liver-Gut Axis.
Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota.
Exploration of the potential mechanism of Baicalin for hepatic fibrosis based on network pharmacology, gut microbiota, and experimental validation.
Effects of glycolysis and polyamine predation on intestinal epithelial barrier in colorectal cancer.
Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage.
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
New mechanism for mesenchymal stem cell microvesicle to restore lung permeability: intracellular S1P signaling pathway independent of S1P receptor-1.
Nicotinamide N-Methyltransferase Remodeled Cell Metabolism and Aggravated Proinflammatory Responses by Activating STAT3/IL1β/PGE(2) Pathway.
Polystyrene nanoparticles enhance the adverse effects of di-(2-ethylhexyl) phthalate on male reproductive system in mice.
Prenatal exposure to titanium dioxide nanoparticles induces persistent neurobehavioral impairments in maternal mice that is associated with microbiota-gut-brain axis.
pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance "One Stone Four Birds" Effect of Rhein on Ulcerative Colitis.
Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis.
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer.
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Gut microbiota dysbiosis induced by polychlorinated biphenyl 126 contributes to increased brain proinflammatory cytokines: Landscapes from the gut-brain axis and fecal microbiota transplantation.
Role of Autotaxin in High Glucose-Induced Human ARPE-19 Cells.
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy.
Coronary Collateral Microcirculation Reserve Becomes Vestigial with Aging.
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2.
Chitosan-chelated zinc modulates ileal microbiota, ileal microbial metabolites, and intestinal function in weaned piglets challenged with Escherichia coli K88.
Effects of intragastric administration of La(2)O(3) nanoparticles on mouse testes.
oprC Impairs Host Defense by Increasing the Quorum-Sensing-Mediated Virulence of Pseudomonas aeruginosa.
An electrochemical biosensor for the detection of epithelial-mesenchymal transition.
Alteration of fecal tryptophan metabolism correlates with shifted microbiota and may be involved in pathogenesis of colorectal cancer.
Mice with pre-existing tumors are vulnerable to postoperative cognitive dysfunction.
LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial-Mesenchymal Transition.
Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function.
High-fat diet promotes experimental colitis by inducing oxidative stress in the colon.
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
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Christofidou ED, Tomazou M, Voutouri C, Michael C, Stylianopoulos T, Spyrou GM, Strati K
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Octreotide attenuates intestinal barrier damage by maintaining basal autophagy in Caco2 cells.
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Revealing the Mechanism of NLRP3 Inflammatory Pathway Activation through K(+) Efflux Induced by PLO via Signal Point Mutations.
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International journal of molecular sciences 2024 Jun 18;25(12)
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International immunopharmacology 2024 Jan 25;127:111290
Neuroprotection of rhubarb extract against cerebral ischaemia-reperfusion injury via the gut-brain axis pathway.
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Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155254
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155254
Intestinal Piezo1 aggravates intestinal barrier dysfunction during sepsis by mediating Ca(2+) influx.
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Journal of translational medicine 2024 Apr 4;22(1):332
Journal of translational medicine 2024 Apr 4;22(1):332
Sedanolide alleviates DSS-induced colitis by modulating the intestinal FXR-SMPD3 pathway in mice.
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Journal of advanced research 2024 Apr 4;
Journal of advanced research 2024 Apr 4;
The coumarin component isofraxidin targets the G-protein-coupled receptor S1PR1 to modulate IL-17 signaling and alleviate ulcerative colitis.
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International immunopharmacology 2024 Apr 20;131:111814
International immunopharmacology 2024 Apr 20;131:111814
Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice.
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Characterization and optimization of variability in a human colonic epithelium culture model.
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bioRxiv : the preprint server for biology 2023 Sep 22;
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Hsa_circRNA_103124 upregulation in Crohn's disease promoted macrophage M1 polarization to maintain an inflammatory microenvironment via activation of the AKT2 and TLR4/NF-κB pathways.
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Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis.
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LKB1 loss promotes colorectal cancer cell metastasis through regulating TNIK expression and actin cytoskeleton remodeling.
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Molecular carcinogenesis 2023 Nov;62(11):1659-1672
Molecular carcinogenesis 2023 Nov;62(11):1659-1672
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International journal of biological macromolecules 2023 May 1;236:123870
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
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iScience 2023 Mar 17;26(3):106151
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iScience 2023 Feb 17;26(2):106003
Tryptophan alleviates lipopolysaccharide-induced liver injury and inflammation by modulating necroptosis and pyroptosis signaling pathways in piglets.
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Animal biotechnology 2023 Dec;34(8):4069-4080
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
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Nature communications 2023 Dec 8;14(1):8141
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International journal of molecular sciences 2023 Aug 15;24(16)
International journal of molecular sciences 2023 Aug 15;24(16)
TAK-242 Ameliorates Hepatic Fibrosis by Regulating the Liver-Gut Axis.
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BioMed research international 2022;2022:4949148
Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota.
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Frontiers in physiology 2022;13:900961
Frontiers in physiology 2022;13:900961
Exploration of the potential mechanism of Baicalin for hepatic fibrosis based on network pharmacology, gut microbiota, and experimental validation.
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Frontiers in microbiology 2022;13:1051100
Frontiers in microbiology 2022;13:1051100
Effects of glycolysis and polyamine predation on intestinal epithelial barrier in colorectal cancer.
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Frontiers in oncology 2022;12:961257
Frontiers in oncology 2022;12:961257
Astrocytic NDRG2-PPM1A interaction exacerbates blood-brain barrier disruption after subarachnoid hemorrhage.
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Science advances 2022 Sep 30;8(39):eabq2423
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Cell death & disease 2022 Sep 12;13(9):785
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Nicotinamide N-Methyltransferase Remodeled Cell Metabolism and Aggravated Proinflammatory Responses by Activating STAT3/IL1β/PGE(2) Pathway.
Yang C, Wang T, Zhu S, Zong Z, Luo C, Zhao Y, Liu J, Li T, Liu X, Liu C, Deng H
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ACS omega 2022 Oct 25;7(42):37509-37519
Polystyrene nanoparticles enhance the adverse effects of di-(2-ethylhexyl) phthalate on male reproductive system in mice.
Li D, Sun W, Jiang X, Yu Z, Xia Y, Cheng S, Mao L, Luo S, Tang S, Xu S, Zou Z, Chen C, Qiu J, Zhou L
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Ecotoxicology and environmental safety 2022 Oct 15;245:114104
Prenatal exposure to titanium dioxide nanoparticles induces persistent neurobehavioral impairments in maternal mice that is associated with microbiota-gut-brain axis.
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Nov;169:113402
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Nov;169:113402
pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance "One Stone Four Birds" Effect of Rhein on Ulcerative Colitis.
Qi S, Luo R, Han X, Nie W, Ye N, Fu C, Gao F
ACS applied materials & interfaces 2022 Nov 16;14(45):50692-50709
ACS applied materials & interfaces 2022 Nov 16;14(45):50692-50709
Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis.
Lv D, Jiang S, Zhang M, Zhu X, Yang F, Wang H, Li S, Liu F, Zeng C, Qin W, Li L, Liu Z
Kidney diseases (Basel, Switzerland) 2022 Jul;8(4):308-318
Kidney diseases (Basel, Switzerland) 2022 Jul;8(4):308-318
The kinase activity of integrin-linked kinase regulates cellular senescence in gastric cancer.
Ji C, Zhang M, Hu J, Cao C, Gu Q, Liu Y, Li X, Xu D, Ying L, Yang Y, Gao H, Li J, Yu L
Cell death & disease 2022 Jul 1;13(7):577
Cell death & disease 2022 Jul 1;13(7):577
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
Wang Y, Wang Q, Duan L, Li X, Yang W, Huang T, Kong M, Guan F, Ma S
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
International journal of biological macromolecules 2022 Dec 1;222(Pt A):759-771
Intestinal epithelial β Klotho is a critical protective factor in alcohol-induced intestinal barrier dysfunction and liver injury.
Hou Z, Ding Q, Li Y, Zhao Z, Yan F, Li Y, Wang X, Xu J, Chen W, Wu G, Ruan X, Zhao L
EBioMedicine 2022 Aug;82:104181
EBioMedicine 2022 Aug;82:104181
Gut microbiota dysbiosis induced by polychlorinated biphenyl 126 contributes to increased brain proinflammatory cytokines: Landscapes from the gut-brain axis and fecal microbiota transplantation.
Li T, Tian D, Lu M, Wang B, Li J, Xu B, Chen H, Wu S
Ecotoxicology and environmental safety 2022 Aug;241:113726
Ecotoxicology and environmental safety 2022 Aug;241:113726
Role of Autotaxin in High Glucose-Induced Human ARPE-19 Cells.
Liu Y, Yamagishi R, Honjo M, Kurano M, Yatomi Y, Igarashi K, Aihara M
International journal of molecular sciences 2022 Aug 16;23(16)
International journal of molecular sciences 2022 Aug 16;23(16)
TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.
Xie C, Zhu J, Yang X, Huang C, Zhou L, Meng Z, Li X, Zhong C
Frontiers in cell and developmental biology 2021;9:645402
Frontiers in cell and developmental biology 2021;9:645402
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy.
Guo W, Li W, Su Y, Liu S, Kan X, Ran X, Cao Y, Fu S, Liu J
International journal of biological sciences 2021;17(15):4271-4284
International journal of biological sciences 2021;17(15):4271-4284
Coronary Collateral Microcirculation Reserve Becomes Vestigial with Aging.
Chen J, Liu X, Qin X, Liu Z, Zhu L, Quan X, Xu Z, Dong H, Zhang Z
Cardiology 2021;146(1):11-18
Cardiology 2021;146(1):11-18
SARS-CoV-2 spike protein dictates syncytium-mediated lymphocyte elimination.
Zhang Z, Zheng Y, Niu Z, Zhang B, Wang C, Yao X, Peng H, Franca DN, Wang Y, Zhu Y, Su Y, Tang M, Jiang X, Ren H, He M, Wang Y, Gao L, Zhao P, Shi H, Chen Z, Wang X, Piacentini M, Bian X, Melino G, Liu L, Huang H, Sun Q
Cell death and differentiation 2021 Sep;28(9):2765-2777
Cell death and differentiation 2021 Sep;28(9):2765-2777
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Huang C, Ou R, Chen X, Zhang Y, Li J, Liang Y, Zhu X, Liu L, Li M, Lin D, Qiu J, Liu G, Zhang L, Wu Y, Tang H, Liu Y, Liang L, Ding Y, Liao W
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Sorafenib derivatives-functionalized gold nanoparticles confer protection against tumor angiogenesis and proliferation via suppression of EGFR and VEGFR-2.
Huang W, Xing Y, Zhu L, Zhuo J, Cai M
Experimental cell research 2021 Sep 1;406(1):112633
Experimental cell research 2021 Sep 1;406(1):112633
Chitosan-chelated zinc modulates ileal microbiota, ileal microbial metabolites, and intestinal function in weaned piglets challenged with Escherichia coli K88.
Hou G, Zhang M, Wang J, Zhu W
Applied microbiology and biotechnology 2021 Oct;105(19):7529-7544
Applied microbiology and biotechnology 2021 Oct;105(19):7529-7544
Effects of intragastric administration of La(2)O(3) nanoparticles on mouse testes.
Yuan L, Bai D, Meng L, Wang H, Sun Z, An T, Chen Z, Deng X, Zhang X
The Journal of toxicological sciences 2020;45(8):411-422
The Journal of toxicological sciences 2020;45(8):411-422
oprC Impairs Host Defense by Increasing the Quorum-Sensing-Mediated Virulence of Pseudomonas aeruginosa.
Gao P, Guo K, Pu Q, Wang Z, Lin P, Qin S, Khan N, Hur J, Liang H, Wu M
Frontiers in immunology 2020;11:1696
Frontiers in immunology 2020;11:1696
An electrochemical biosensor for the detection of epithelial-mesenchymal transition.
Du X, Zhang Z, Zheng X, Zhang H, Dong D, Zhang Z, Liu M, Zhou J
Nature communications 2020 Jan 10;11(1):192
Nature communications 2020 Jan 10;11(1):192
Alteration of fecal tryptophan metabolism correlates with shifted microbiota and may be involved in pathogenesis of colorectal cancer.
Sun XZ, Zhao DY, Zhou YC, Wang QQ, Qin G, Yao SK
World journal of gastroenterology 2020 Dec 7;26(45):7173-7190
World journal of gastroenterology 2020 Dec 7;26(45):7173-7190
Mice with pre-existing tumors are vulnerable to postoperative cognitive dysfunction.
Wu T, Wang X, Zhang R, Jiao Y, Yu W, Su D, Zhao Y, Tian J
Brain research 2020 Apr 1;1732:146650
Brain research 2020 Apr 1;1732:146650
LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial-Mesenchymal Transition.
Cai H, Li J, Zhang Y, Liao Y, Zhu Y, Wang C, Hou J
Frontiers in oncology 2019;9:1446
Frontiers in oncology 2019;9:1446
Huang-Lian-Jie-Du Decoction Ameliorates Acute Ulcerative Colitis in Mice via Regulating NF-κB and Nrf2 Signaling Pathways and Enhancing Intestinal Barrier Function.
Yuan Z, Yang L, Zhang X, Ji P, Hua Y, Wei Y
Frontiers in pharmacology 2019;10:1354
Frontiers in pharmacology 2019;10:1354
High-fat diet promotes experimental colitis by inducing oxidative stress in the colon.
Li X, Wei X, Sun Y, Du J, Li X, Xun Z, Li YC
American journal of physiology. Gastrointestinal and liver physiology 2019 Oct 1;317(4):G453-G462
American journal of physiology. Gastrointestinal and liver physiology 2019 Oct 1;317(4):G453-G462
Native Coronary Collateral Microcirculation Reserve in Rat Hearts.
Liu X, Dong H, Huang B, Miao H, Xu Z, Yuan Y, Qiu F, Chen J, Zhang H, Liu Z, Quan X, Zhu L, Zhang Z
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Journal of the American Heart Association 2019 Mar 5;8(5):e011220
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
Han J, Guo D, Sun XY, Wang JM, Ouyang JM, Gui BS
Scientific reports 2019 Jul 8;9(1):9871
Scientific reports 2019 Jul 8;9(1):9871
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