orb151464

antibody from Biorbyt
Targeting: SOD2 GClnc1
Provider product page for orb151464
Western blot
ELISA
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
orb151464 - Provider product page
Provider
Biorbyt
Product name
SOD (Mn) antibody
Antibody type
Polyclonal
Description
Rabbit polyclonal to SOD (HRP). Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body. It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms. There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge. The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space. SOD3 can also be distinguished by its heparin-binding capacity..
Reactivity
Human, Mouse, Rat, Bovine, Canine, Guinea Pig, Hamster, Porcine, Rabbit, Sheep, Simian
Host
Rabbit
Conjugate
Horseradish Peroxidase
Vial size
100 ug
Concentration
1 mg/ml
Storage
Conjugated antibodies should be stored at 4°C
SOD2 protein structure - orb151464 shown in red.