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- Antibody Data
- Antigen structure
- References [20]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 18257-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18257-1-AP, RRID:AB_10598162
- Product name
- GSR antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GSR antibody (Cat. #18257-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Physiological and molecular predictors of cycling sprint performance.
MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells.
Exacerbated response to oxidative stress in the Retinitis Pigmentosa Cerkl(KD/KO) mouse model triggers retinal degeneration pathways upon acute light stress.
Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness.
Extracellular arginine availability modulates eIF2α O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis.
A Mango Leaf Extract (Zynamite(®)) Combined with Quercetin Has Exercise-Mimetic Properties in Human Skeletal Muscle.
A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites.
GSK 650394 Inhibits Osteoclasts Differentiation and Prevents Bone Loss via Promoting the Activities of Antioxidant Enzymes In Vitro and In Vivo.
Fast regulation of the NF-κB signalling pathway in human skeletal muscle revealed by high-intensity exercise and ischaemia at exhaustion: Role of oxygenation and metabolite accumulation.
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
Anti-Inflammatory Effect of Dimethyl Fumarate Associates with the Inhibition of Thioredoxin Reductase 1 in RAW 264.7 Cells.
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Desflurane Preconditioning Protects Against Renal Ischemia-Reperfusion Injury and Inhibits Inflammation and Oxidative Stress in Rats Through Regulating the Nrf2-Keap1-ARE Signaling Pathway.
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death.
GSH-dependent antioxidant defense contributes to the acclimation of colon cancer cells to acidic microenvironment.
The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Galvan-Alvarez V, Gallego-Selles A, Martinez-Canton M, Perez-Suarez I, Garcia-Gonzalez E, Martin-Rincon M, Calbet JAL
Scandinavian journal of medicine & science in sports 2024 Jan;34(1):e14545
Scandinavian journal of medicine & science in sports 2024 Jan;34(1):e14545
MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells.
Daimon T, Bhattacharya A, Wang K, Haratake N, Nakashoji A, Ozawa H, Morimoto Y, Yamashita N, Kosaka T, Oya M, Kufe DW
Cell death discovery 2024 Jan 5;10(1):9
Cell death discovery 2024 Jan 5;10(1):9
Exacerbated response to oxidative stress in the Retinitis Pigmentosa Cerkl(KD/KO) mouse model triggers retinal degeneration pathways upon acute light stress.
García-Arroyo R, Domènech EB, Herrera-Úbeda C, Asensi MA, Núñez de Arenas C, Cuezva JM, Garcia-Fernàndez J, Pallardó FV, Mirra S, Marfany G
Redox biology 2023 Oct;66:102862
Redox biology 2023 Oct;66:102862
Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness.
Galvan-Alvarez V, Gallego-Selles A, Martinez-Canton M, García-Gonzalez E, Gelabert-Rebato M, Ponce-Gonzalez JG, Larsen S, Morales-Alamo D, Losa-Reyna J, Perez-Suarez I, Dorado C, Perez-Valera M, Holmberg HC, Boushel R, de Pablos Velasco P, Helge JW, Martin-Rincon M, Calbet JAL
Free radical biology & medicine 2023 Nov 20;209(Pt 2):282-291
Free radical biology & medicine 2023 Nov 20;209(Pt 2):282-291
Extracellular arginine availability modulates eIF2α O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis.
Hung YW, Ouyang C, Ping X, Qi Y, Wang YC, Kung HJ, Ann DK
Journal of biomedical science 2023 May 22;30(1):32
Journal of biomedical science 2023 May 22;30(1):32
A Mango Leaf Extract (Zynamite(®)) Combined with Quercetin Has Exercise-Mimetic Properties in Human Skeletal Muscle.
Martinez-Canton M, Galvan-Alvarez V, Garcia-Gonzalez E, Gallego-Selles A, Gelabert-Rebato M, Garcia-Perez G, Santana A, Lopez-Rios L, Vega-Morales T, Martin-Rincon M, Calbet JAL
Nutrients 2023 Jun 23;15(13)
Nutrients 2023 Jun 23;15(13)
A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites.
Wang Y, Tang B, Li H, Zheng J, Zhang C, Yang Z, Tan X, Luo P, Ma L, Wang Y, Long L, Chen Z, Xiao Z, Ma L, Zhou J, Wang Y, Shi C
EBioMedicine 2023 Apr;90:104480
EBioMedicine 2023 Apr;90:104480
GSK 650394 Inhibits Osteoclasts Differentiation and Prevents Bone Loss via Promoting the Activities of Antioxidant Enzymes In Vitro and In Vivo.
Jin LY, Huo SC, Guo C, Liu HY, Xu S, Li XF
Oxidative medicine and cellular longevity 2022;2022:3458560
Oxidative medicine and cellular longevity 2022;2022:3458560
Fast regulation of the NF-κB signalling pathway in human skeletal muscle revealed by high-intensity exercise and ischaemia at exhaustion: Role of oxygenation and metabolite accumulation.
Gallego-Selles A, Galvan-Alvarez V, Martinez-Canton M, Garcia-Gonzalez E, Morales-Alamo D, Santana A, Gonzalez-Henriquez JJ, Dorado C, Calbet JAL, Martin-Rincon M
Redox biology 2022 Sep;55:102398
Redox biology 2022 Sep;55:102398
Glucose-6-phosphate dehydrogenase exerts antistress effects independently of its enzymatic activity.
Jin X, Li X, Li L, Zhong B, Hong Y, Niu J, Li B
The Journal of biological chemistry 2022 Dec;298(12):102587
The Journal of biological chemistry 2022 Dec;298(12):102587
Anti-Inflammatory Effect of Dimethyl Fumarate Associates with the Inhibition of Thioredoxin Reductase 1 in RAW 264.7 Cells.
Yang R, Sun S, Guo Y, Meng Y, Liu H, Shi M, Guan S, Xu J
Molecules (Basel, Switzerland) 2022 Dec 23;28(1)
Molecules (Basel, Switzerland) 2022 Dec 23;28(1)
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Chang MT, Tsai LC, Nakagawa-Goto K, Lee KH, Shyur LF
Pharmacological research 2022 Apr;178:106148
Pharmacological research 2022 Apr;178:106148
Desflurane Preconditioning Protects Against Renal Ischemia-Reperfusion Injury and Inhibits Inflammation and Oxidative Stress in Rats Through Regulating the Nrf2-Keap1-ARE Signaling Pathway.
Zheng Y, Lu H, Huang H
Drug design, development and therapy 2020;14:1351-1362
Drug design, development and therapy 2020;14:1351-1362
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Wang Z, Cai L, Li H, Liang M, Zhang Y, Wu Q, Yang L
Journal of food biochemistry 2020 May;44(5):e13180
Journal of food biochemistry 2020 May;44(5):e13180
l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.
Wang Z, Liang M, Li H, Cai L, He H, Wu Q, Yang L
Journal of the science of food and agriculture 2019 Aug 15;99(10):4849-4862
Journal of the science of food and agriculture 2019 Aug 15;99(10):4849-4862
Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death.
Blecha J, Novais SM, Rohlenova K, Novotna E, Lettlova S, Schmitt S, Zischka H, Neuzil J, Rohlena J
Free radical biology & medicine 2017 Nov;112:253-266
Free radical biology & medicine 2017 Nov;112:253-266
GSH-dependent antioxidant defense contributes to the acclimation of colon cancer cells to acidic microenvironment.
Zhao M, Liu Q, Gong Y, Xu X, Zhang C, Liu X, Zhang C, Guo H, Zhang X, Gong Y, Shao C
Cell cycle (Georgetown, Tex.) 2016;15(8):1125-33
Cell cycle (Georgetown, Tex.) 2016;15(8):1125-33
The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer.
Zheng ZG, Xu H, Suo SS, Xu XL, Ni MW, Gu LH, Chen W, Wang LY, Zhao Y, Tian B, Hua YJ
Scientific reports 2016 May 19;6:26093
Scientific reports 2016 May 19;6:26093
Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes.
Dong K, Wu M, Liu X, Huang Y, Zhang D, Wang Y, Yan LJ, Shi D
Free radical biology & medicine 2016 Dec;101:334-347
Free radical biology & medicine 2016 Dec;101:334-347
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
Wu H, Xiao Y, Zhang S, Ji S, Wei L, Fan F, Geng J, Tian J, Sun X, Qin F, Jin C, Lin J, Yin ZY, Zhang T, Luo L, Li Y, Song S, Lin SC, Deng X, Camargo F, Avruch J, Chen L, Zhou D
Cell reports 2013 May 30;3(5):1663-77
Cell reports 2013 May 30;3(5):1663-77
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 18257-1-AP(GSR antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using GSR antibody 18257-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
