11103-1-AP

antibody from Proteintech Group

Targeting: GATA2 NFE1B

Provider product page for 11103-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [25]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 11103-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#11103-1-AP, RRID:AB_10914503
Product name: GATA2 antibody
Antibody type: Polyclonal
Description: GATA2 antibody (Cat. #11103-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

GATA2 protein structure - 11103-1-AP shown in red.

Submitted references Oligomeric lactic acid nanoplastics induce intrauterine growth restriction in mice by disrupting GATA2-mediated placental vascular development.

Lv J, Wang M, Shi C, Wang Y, Zhang Y, Gao C, Bi TQ, Yang J, Xu Y, Wang Q, Wang H, Xu DX, Fang M, Huang Y
PLoS biology 2026 Mar;24(3):e3003676

Ginsenoside Rd promotes cardiac regeneration through PPARG/HMGCS2-driven ketone body metabolic reprogramming in myocardial ischemia-reperfusion injury.

Zhang H, Lin A, Zhai C, Lai T, Gong X, Wang M, Wu H, Ye T, Wang L, Tawulie D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157694

Endothelial FUNDC1 regulates metabolic reprogramming and the obesity-diabetes transition through the SIRT3/GATA2/endothelin-1 axis.

Li J, Li D, Zhao F, Wang Y, Yao H, Wu Y, An J, Liu Z, Ding Y, Zou MH
Nature communications 2026 Jan 16;17(1):1836

Histone lactylation exacerbates acute lung injury in septic mice by promoting ferroptosis in pulmonary microvascular endothelial cells.

Fang P, Li S, Lu ZQ, Xia DL, Xu MM, Pan JJ, Fu L, Sun GY, You QH
Burns & trauma 2025;13:tkaf056

IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury.

Su H, Lin X, Paredong A, Yao C, Zhang Y, Geng M, Guan Y, Gong L, Jiang F, Lv Q, Shou S, Jin H
Frontiers in molecular biosciences 2025;12:1538526

Growth hormone regulates deiodinase type 2 and 3 expression via GATA.

Mitsutani M, Hano H, Yokoyama M, Matsushita M, Hayashi M, Yamauchi I, Tagami T, Moriyama K
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2025 Oct;82:101659

PU.1/Spi1 exacerbates ischemia-reperfusion induced acute kidney injury via upregulating Gata2 and promoting fibroblast activation.

Zong C, Xu GL, Ning M, Li JY, Wang X, Guo HJ, Zhang LH, Zhou L, Xu C, Yang ZH, Lu LM, Niu JY
Acta pharmacologica Sinica 2025 Aug;46(8):2251-2266

Pkd2l1 deletion inhibits the neurogenesis of cerebrospinal fluid-contacting neurons and impedes spinal cord injury repair.

Zhang Y, Cao L, Yan H, Luo Z, Chen C, Shangguan Z, Li Q, Shi X, Yang L, Tan W, Yang S, Fu J, Wang C, Dou X, Li Q
Cell death discovery 2025 Apr 23;11(1):194

GATA2 participates in protection against hypoxia-induced pulmonary vascular remodeling.

Shirota Y, Ohmori S, Engel JD, Moriguchi T
PloS one 2024;19(12):e0315446

GATA2 downregulation contributes to pro-inflammatory phenotype and defective phagocytosis of pulmonary macrophages in chronic obstructive pulmonary disease.

Shen S, Huang Q, Liu L, Zou X, Kang T, Wu J
Aging 2024 Oct 7;16(19):12928-12951

Somatic mutations in four novel genes contribute to homologous recombination deficiency in breast cancer: a real-world clinical tumor sequencing study.

Huang Y, Qiu Y, Ding L, Ren S, Jiang Y, Luo J, Huang J, Yin X, Fu S, Zhao J, Hu K, Liao J
The journal of pathology. Clinical research 2024 Mar;10(2):e12367

ARID1A recruits GATA2 to regulate the senescence of trophoblast cells under high-glucose condition.

Huang Y, Yang X, Wang Y, Nai Y, Ji L, Zhu H, Lai R, Wang QT, Hu H, Wang L
Placenta 2024 Dec;158:156-164

miR-107 reverses the multidrug resistance of gastric cancer by targeting the CGA/EGFR/GATA2 positive feedback circuit.

Wang P, Zhou Y, Wang J, Zhou Y, Zhang X, Liu Y, Li A, He Y, Chen S, Qian A, Wang X, Nie Y, Fan D, Cao T, Lu Y, Zhao X
The Journal of biological chemistry 2024 Aug;300(8):107522

Identification of lysosomal genes associated with prognosis in lung adenocarcinoma.

Li H, Sha X, Wang W, Huang Z, Zhang P, Liu L, Wang S, Zhou Y, He S, Shi J
Translational lung cancer research 2023 Jul 31;12(7):1477-1495

Integrative analysis of the ST6GALNAC family identifies GATA2-upregulated ST6GALNAC5 as an adverse prognostic biomarker promoting prostate cancer cell invasion.

Li M, Ma Z, Zhang Y, Feng H, Li Y, Sang W, Zhu R, Huang R, Yan J
Cancer cell international 2023 Jul 19;23(1):141

Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR-RUNX1.

Zhou L, Wu D, Zhou Y, Wang D, Fu H, Huang Q, Qin G, Chen J, Lv J, Lai S, Zhang H, Tang K, Ma J, Fiskesund R, Zhang Y, Zhang X, Huang B
Nature immunology 2023 Dec;24(12):2042-2052

Downregulation of AC092894.1 promotes oxaliplatin resistance in colorectal cancer via the USP3/AR/RASGRP3 axis.

Zheng Z, Wu M, Li H, Xu W, Yang M, Pan K, Ni Y, Jiang T, Zheng H, Jin X, Zhang Y, Ding L, Fu J
BMC medicine 2023 Apr 3;21(1):132

Bone morphogenetic protein 2- and estradiol-17β-induced changes in ovarian transcriptome during primordial follicle formation†.

Chakraborty P, Anderson RL, Roy SK
Biology of reproduction 2022 Sep 12;107(3):800-812

Functional Lactotrophs in Induced Adenohypophysis Differentiated From Human iPS Cells.

Miyake N, Nagai T, Suga H, Osuka S, Kasai T, Sakakibara M, Soen M, Ozaki H, Miwata T, Asano T, Kano M, Muraoka A, Nakanishi N, Nakamura T, Goto M, Yasuda Y, Kawaguchi Y, Miyata T, Kobayashi T, Sugiyama M, Onoue T, Hagiwara D, Iwama S, Iwase A, Inoshita N, Arima H, Kajiyama H
Endocrinology 2022 Mar 1;163(3)

Divergent transcriptional regulation of astrocyte reactivity across disorders.

Burda JE, O'Shea TM, Ao Y, Suresh KB, Wang S, Bernstein AM, Chandra A, Deverasetty S, Kawaguchi R, Kim JH, McCallum S, Rogers A, Wahane S, Sofroniew MV
Nature 2022 Jun;606(7914):557-564

GATA2 regulates the CAD susceptibility gene ADTRP rs6903956 through preferential interaction with the G allele.

Luo C, Tang B, Qin S, Yuan C, Du Y, Yang J
Molecular genetics and genomics : MGG 2021 Jul;296(4):799-808

LncRNA H19-Derived miR-675-5p Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting GATA2 and Subsequently Activating Matrix Metalloproteinases.

Ogoyama M, Ohkuchi A, Takahashi H, Zhao D, Matsubara S, Takizawa T
International journal of molecular sciences 2021 Jan 27;22(3)

PGE2 and Thrombin Induce Myofibroblast Transdifferentiation via Activin A and CTGF in Endometrial Stromal Cells.

Kusama K, Fukushima Y, Yoshida K, Azumi M, Yoshie M, Mizuno Y, Kajihara T, Tamura K
Endocrinology 2021 Dec 1;162(12)

The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiation and Acute Myeloid Leukemia.

Shen C, Chen MT, Zhang XH, Yin XL, Ning HM, Su R, Lin HS, Song L, Wang F, Ma YN, Zhao HL, Yu J, Zhang JW
PLoS genetics 2016 Sep;12(9):e1006259

Functional screen reveals essential roles of miR-27a/24 in differentiation of embryonic stem cells.

Ma Y, Yao N, Liu G, Dong L, Liu Y, Zhang M, Wang F, Wang B, Wei X, Dong H, Wang L, Ji S, Zhang J, Wang Y, Huang Y, Yu J
The EMBO journal 2015 Feb 3;34(3):361-78

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HeLa cells were subjected to SDS PAGE followed by western blot with 11103-1-AP(GATA2 antibody) at dilution of 1:300
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using GATA2 antibody 11103-1-AP at 1:100 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
Sample type: cell line