Antibody data
- Antibody Data
- Antigen structure
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- Product number
- TAB-666CL - Provider product page
- Provider
- Creative Biolabs
- Product name
- Anti-Human VWF Therapeutic Single Domain Antibody (ALX-0681)
- Antibody type
- Other
- Description
- Recombinant Humanized monoclonal Single Domain Antibody expressed in E. coli binding to Human VWF. ALX-0681 is a therapeutic Single Domain Antibody targeting the A1-domain of VWF. It inhibits the interaction between ultra-large VWF and platelet GpIb-IX-V, which plays a crucial role in the pathogenesis of thrombotic thrombocytopenic purpura (TTP). ALX-0681 can successfully treat and prevent the most important hallmarks of acquired TTP without evidence of a severe bleeding risk. Therefore, ALX-0681 offers an attractive new therapeutic option for acquired TTP in the clinical setting.
- Reactivity
- Human
- Host
- Other
- Vial size
- 1 mg
- Storage
- Can be stored at 4° C. For long term storage, aliquot and store at -20° C. Avoid repeated freezing and thawing cycles.
- Handling
- The antibody solution should be gently mixed before use.
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