TAB-666CL

antibody from Creative Biolabs
Targeting: VWF F8VWF
Provider product page for TAB-666CL
Other assay

Antibody data

Product number
TAB-666CL - Provider product page
Provider
Creative Biolabs
Product name
Anti-Human VWF Therapeutic Single Domain Antibody (ALX-0681)
Antibody type
Other
Description
Recombinant Humanized monoclonal Single Domain Antibody expressed in E. coli binding to Human VWF. ALX-0681 is a therapeutic Single Domain Antibody targeting the A1-domain of VWF. It inhibits the interaction between ultra-large VWF and platelet GpIb-IX-V, which plays a crucial role in the pathogenesis of thrombotic thrombocytopenic purpura (TTP). ALX-0681 can successfully treat and prevent the most important hallmarks of acquired TTP without evidence of a severe bleeding risk. Therefore, ALX-0681 offers an attractive new therapeutic option for acquired TTP in the clinical setting.
Reactivity
Human
Host
Other
Vial size
1  mg
Storage
Can be stored at 4° C. For long term storage, aliquot and store at -20° C. Avoid repeated freezing and thawing cycles.
Handling
The antibody solution should be gently mixed before use.
VWF protein structure - TAB-666CL shown in red.