Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM00428G - Provider product page
- Provider
- Leading Biology
- Product name
- von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody - Without BSA and Azid
- Antibody type
- Monoclonal
- Description
- von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposiā€™s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- 3E2D10
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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