FNab05379

antibody from FineTest Biotech

Targeting: MSL1 DKFZp686P24239, hMSL1, MSL-1

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab05379 - Provider product page
Provider: FineTest Biotech
Product name: MSL1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16'(H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34'(H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4'(H3K4me) and 'Lys-79'(H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: male-specific lethal 1 homolog(Dros ophila)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

MSL1 protein structure - FNab05379 shown in red.