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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA035364 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA035364, RRID:AB_10601095
- Product name
- Anti-CCDC39
- Antibody type
- Polyclonal
- Description
- Affinity purified using the PrEST antigen as affinity ligand
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
ILDNELTETISAQLELDKAAQDFRKIHNERQELIK
QWENTIEQMQKRDGDIDNCALELARIKQETREKEN
LVKEKIKFLESEIGNNTEFEKRISVADR- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Submitted references Structure, interaction and nervous connectivity of beta cell primary cilia
Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models
Biallelic Variants in CCDC39 Gene Lead to Primary Ciliary Dyskinesia and Kartagener Syndrome.
A quantitative super-resolution imaging toolbox for diagnosis of motile ciliopathies
Lowe syndrome–linked endocytic adaptors direct membrane cycling kinetics with OCRL inDictyostelium discoideum
Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs
Müller A, Klena N, Pang S, Garcia L, Topcheva O, Aurrecoechea Duran S, Sulaymankhil D, Seliskar M, Mziaut H, Schöniger E, Friedland D, Kipke N, Kretschmar S, Münster C, Weitz J, Distler M, Kurth T, Schmidt D, Hess H, Xu C, Pigino G, Solimena M
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models
Liu C, Si W, Tu C, Tian S, He X, Wang S, Yang X, Yao C, Li C, Kherraf Z, Ye M, Zhou Z, Ma Y, Gao Y, Li Y, Liu Q, Tang S, Wang J, Saiyin H, Zhao L, Yang L, Meng L, Chen B, Tang D, Zhou Y, Wu H, Lv M, Tan C, Lin G, Kong Q, Shi H, Su Z, Li Z, Yao Y, Jin L, Zheng P, Ray P, Tan Y, Cao Y, Zhang F
The American Journal of Human Genetics 2023;110(3):516-530
The American Journal of Human Genetics 2023;110(3):516-530
Biallelic Variants in CCDC39 Gene Lead to Primary Ciliary Dyskinesia and Kartagener Syndrome.
Shi X, Geng H, Yu H, Hu X, Wang G, Yang J, Zhao H
BioMed research international 2022;2022:7130555
BioMed research international 2022;2022:7130555
A quantitative super-resolution imaging toolbox for diagnosis of motile ciliopathies
Liu Z, Nguyen Q, Guan Q, Albulescu A, Erdman L, Mahdaviyeh Y, Kang J, Ouyang H, Hegele R, Moraes T, Goldenberg A, Dell S, Mennella V
Science Translational Medicine 2020;12(535)
Science Translational Medicine 2020;12(535)
Lowe syndrome–linked endocytic adaptors direct membrane cycling kinetics with OCRL inDictyostelium discoideum
Luscher A, Fröhlich F, Barisch C, Littlewood C, Metcalfe J, Leuba F, Palma A, Pirruccello M, Cesareni G, Stagi M, Walther T, Soldati T, De Camilli P, Swan L, Gruenberg J
Molecular Biology of the Cell 2019;30(17):2268-2282
Molecular Biology of the Cell 2019;30(17):2268-2282
Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam
Emmert A, Iwasawa E, Shula C, Schultz P, Lindquist D, Dunn R, Fugate E, Hu Y, Mangano F, Goto J
Disease Models & Mechanisms 2019;12(11)
Disease Models & Mechanisms 2019;12(11)
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
Tarkar A, Loges NT, Slagle CE, Francis R, Dougherty GW, Tamayo JV, Shook B, Cantino M, Schwartz D, Jahnke C, Olbrich H, Werner C, Raidt J, Pennekamp P, Abouhamed M, Hjeij R, Köhler G, Griese M, Li Y, Lemke K, Klena N, Liu X, Gabriel G, Tobita K, Jaspers M, Morgan LC, Shapiro AJ, Letteboer SJ, Mans DA, Carson JL, Leigh MW, Wolf WE, Chen S, Lucas JS, Onoufriadis A, Plagnol V, Schmidts M, Boldt K, UK10K, Roepman R, Zariwala MA, Lo CW, Mitchison HM, Knowles MR, Burdine RD, Loturco JJ, Omran H
Nature genetics 2013 Sep;45(9):995-1003
Nature genetics 2013 Sep;45(9):995-1003
CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs
Merveille A, Davis E, Becker-Heck A, Legendre M, Amirav I, Bataille G, Belmont J, Beydon N, Billen F, Clément A, Clercx C, Coste A, Crosbie R, de Blic J, Deleuze S, Duquesnoy P, Escalier D, Escudier E, Fliegauf M, Horvath J, Hill K, Jorissen M, Just J, Kispert A, Lathrop M, Loges N, Marthin J, Momozawa Y, Montantin G, Nielsen K, Olbrich H, Papon J, Rayet I, Roger G, Schmidts M, Tenreiro H, Towbin J, Zelenika D, Zentgraf H, Georges M, Lequarré A, Katsanis N, Omran H, Amselem S
Nature Genetics 2010;43(1):72-78
Nature Genetics 2010;43(1):72-78
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and tonsil tissues using HPA035364 antibody. Corresponding CCDC39 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
