Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60875 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PROC polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human PROC.
- Description
- Protein C is a vitamin K-dependent plasma protein that is produced in the liver and made up of two polypeptide chains. It is an important anti-coagulant activated by Thrombin bound to an endothelial surface receptor and it enzymatically cleaves activated forms of Factors V and VIII, thus inhibiting blood coagulation. Protein C is similar to the prothrombin group of blood coagulation factors in its primary structure. Normal protein C concentration in human plasma is approximately 1-3 ng/ml and the proenzyme concentration is approximately 3 Ã×g/ml. Protein C deficiency is associated with inherited thrombophilia, a rare genetic disorder that predisposes affected individuals to venous thrombosis and habitual abortion.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of PROC pAb at 1:500 dilutionLane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysateLane3:H9C2 whole cell lysateLane4:HELA whole cell lysate