Antibody data
- Antibody Data
- Antigen structure
- References [1]
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- Product number
- 819 - Provider product page
- Provider
- YO Proteins AB
- Proper citation
- YO Proteins Cat#819, RRID:AB_2185109
- Product name
- Mouse anti-human CD62 (P-selectin) monoclonal antibody, clone CRC81
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody anti-human CD62 (P-selectin, GMP 140, PADGEM) (clone CRC81, IgG1 kappa fraction). Reacts with CD62 antigen (P-selectin, integral membrane sialoglycoprotein 140 kDa, GMP-140, granule membrane protein 140, PADGEM), which is expressed in platelet alpha granules that are translocated to the platelet surface upon activation with strong agonists. A similar protein, present in endothelial cell Weibel-Palade bodies, is transiently expressed on the surface of activated endothelial cells and functions as adhesion molecule for granulocytes. The antibody does not interfere with the functional activity of CD62 as an adhesion receptor for neutrophils
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 1 ml
Submitted references [Interaction of a monoclonal antibody to P-selectin with activated platelets and endothelial cells. Heterogeneity of expressing P-selectin in human aorta endothelial cells].
Byzova TV, Romanov IuA, Blasik TN, Mazurov AV
Biokhimiia (Moscow, Russia) 1995 Aug;60(8):1292-301
Biokhimiia (Moscow, Russia) 1995 Aug;60(8):1292-301
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