11-0628-42
antibody from Invitrogen Antibodies
Targeting: SELP
CD62, CD62P, GMP140, GRMP, PADGEM, PSEL
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 11-0628-42 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD62P (P-Selectin) Monoclonal Antibody (AK-4), FITC, eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: The AK-4 monoclonal antibody reacts with human CD62P, a 140 kDa transmembrane glycoprotein also known as P-Selectin. Upon activation, CD62P is rapidly transported from its cytoplasmic stores in the Weibel-Palade bodies of endothelial cells or the alpha-granules of platelets to the surface. CD62P initiates the adhesive interaction between endothelial cells and neutrophils and monocytes during the inflammatory reaction and is also involved in the interaction of platelets with monocytes and neutrophils.
- Conjugate
- Green dye
- Antibody clone number
- AK-4
- Concentration
- 5 µL/Test
Submitted references Efficacy of different hemodialysis methods on dendritic cell marker CD40 and CD80 and platelet activation marker CD62P and P10 in patients with chronic renal failure.
Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620.
Wang XF, Zhang BH, Lu XQ, Wang P
Journal of clinical laboratory analysis 2019 Mar;33(3):e22713
Journal of clinical laboratory analysis 2019 Mar;33(3):e22713
Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620.
Jia Y, Zhang S, Miao L, Wang J, Jin Z, Gu B, Duan Z, Zhao Z, Ma S, Zhang W, Li Z
Oncology reports 2015 Jun;33(6):2681-8
Oncology reports 2015 Jun;33(6):2681-8
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Staining of human peripheral blood mononuclear cells with CD45 Pacific Blue, CD41 APC and CD62P FITC. As expected based on known relative expression patterns, CD62P clone AK-4 stains a subset of CD45 negative cells (green), but not lymphocytes (pink), monocytes (orange) and granulocytes (blue).
- Conjugate
- Green dye