Antibody data
- Antibody Data
- Antigen structure
- References [163]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10831-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10831-1-AP, RRID:AB_2264494
- Product name
- Icam-1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ICAM-1 antibody (Cat. #10831-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Intercellular adhesion molecule-1 suppresses TMZ chemosensitivity in acquired TMZ-resistant gliomas by increasing assembly of ABCB1 on the membrane.
Esaxerenone Inhibits Interferon-γ Induced Pyroptosis of Macrophages in the Lungs of Aldosterone-treated Mice.
REXO2 up-regulation is positively correlated with poor prognosis and tumor immune infiltration in hepatocellular carcinoma.
Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids.
Quercetin attenuates inflammation in rosacea by directly targeting p65 and ICAM-1.
Ginsenoside Rg1 alleviates vascular remodeling in hypoxia-induced pulmonary hypertension mice through the calpain-1/STAT3 signaling pathway.
Ciliary neurotrophic factor promotes the development of homocysteine-induced vascular endothelial injury through inflammation mediated by the JAK2/STAT3 signaling pathway.
iNOS inhibitor S-methylisothiourea alleviates smoke inhalation-induced acute lung injury by suppressing inflammation and macrophage infiltration.
The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression.
Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs.
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
Increased expression of cell adhesion molecules in myofasciitis.
Sclareol attenuates liver fibrosis through SENP1-mediated VEGFR2 SUMOylation and inhibition of downstream STAT3 signaling.
Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF.
ERβ promoted invadopodia formation-mediated non-small cell lung cancer metastasis via the ICAM1/p-Src/p-Cortactin signaling pathway.
Salvianolic acid B inhibits atherosclerosis and TNF-α-induced inflammation by regulating NF-κB/NLRP3 signaling pathway.
Chimpanzee adenovirus-mediated multiple gene therapy for age-related macular degeneration.
Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Biomimetic nanoparticles loaded lutein functionalized by macrophage membrane for targeted amelioration pressure overload-induced cardiac fibrosis.
Tissue-derived exosome proteomics identifies promising diagnostic biomarkers for esophageal cancer.
Endogenous FGF1 Deficiency Aggravates Doxorubicin-Induced Hepatotoxicity.
ICAM-1-suPAR-CD11b Axis Is a Novel Therapeutic Target for Metastatic Triple-Negative Breast Cancer.
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.
PbO nanoparticles increase the expression of ICAM-1 and VCAM-1 by increasing reactive oxygen species production in choroid plexus.
The Effect of Cholesterol Efflux on Endothelial Dysfunction Caused by Oxidative Stress.
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Sitagliptin therapy improves myocardial perfusion and arteriolar collateralization in chronically ischemic myocardium: A pilot study.
Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice.
Skewing cPLA(2)α activity toward oxoeicosanoid production promotes neutrophil N2 polarization, wound healing, and the response to sepsis.
Disturbed Flow-Facilitated Margination and Targeting of Nanodisks Protect against Atherosclerosis.
Fyn deficiency inhibits oxidative stress by decreasing c-Cbl-mediated ubiquitination of Sirt1 to attenuate diabetic renal fibrosis.
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
KPNA2 Silencing, Regulated by E3 Ubiquitin Ligase FBXW7, Alleviates Endothelial Dysfunction and Inflammation Through Inhibiting the Nuclear Translocation of p65 and IRF3: A Possible Therapeutic Approach for Atherosclerosis.
Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increased Mitochondrial Fission In Vitro and Atherosclerosis in High-Fat-Diet-Fed ApoE(-/-) Mice.
Connexin32 Promotes the Activation of Foxo3a to Ameliorate Diabetic Nephropathy via Inhibiting the Polyubiquitination and Degradation of Sirt1.
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Protective Role of Vitamin K3 on SARS-CoV-2 Structural Protein-Induced Inflammation and Cell Death.
Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury.
Interaction of RARRES1 with ICAM1 modulates macrophages to suppress the progression of kidney renal clear cell carcinoma.
Circulating galectin-3 promotes tumor-endothelium-adhesion by upregulating ICAM-1 in endothelium-derived extracellular vesicles.
Momordica charantia Exosome-Like Nanoparticles Exert Neuroprotective Effects Against Ischemic Brain Injury via Inhibiting Matrix Metalloproteinase 9 and Activating the AKT/GSK3β Signaling Pathway.
Plasma Exosomes Transfer miR-885-3p Targeting the AKT/NFκB Signaling Pathway to Improve the Sensitivity of Intravenous Glucocorticoid Therapy Against Graves Ophthalmopathy.
ICAM-1-related noncoding RNA accelerates atherosclerosis by amplifying NF-κB signaling.
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.
Macrophage-derived exosomal miR-4532 promotes endothelial cells injury by targeting SP1 and NF-κB P65 signalling activation.
Lack of NPR1 Increases Vascular Endothelial Adhesion through Induction of Integrin Beta 4.
7-Methoxyisoflavone suppresses vascular endothelial inflammation by inhibiting the expression of endothelial adhesion molecules.
Neutrophil extracellular traps: A novel therapeutic target for intracranial hemorrhage.
Triterpenoid saponins of Ilex pubescens against TNF-α induced inflammation and apoptosis in human umbilical vein endothelial cells via autophagy pathway.
Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis.
LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.
Tumor endothelial cell-induced CD8(+) T-cell exhaustion via GPNMB in hepatocellular carcinoma.
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Neutrophil membrane-mimicking nanodecoys with intrinsic anti-inflammatory properties alleviate sepsis-induced acute liver injury and lethality in a mouse endotoxemia model.
Dihydrohomoplantagin and Homoplantaginin, Major Flavonoid Glycosides from Salvia plebeia R. Br. Inhibit oxLDL-Induced Endothelial Cell Injury and Restrict Atherosclerosis via Activating Nrf2 Anti-Oxidation Signal Pathway.
Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma.
Artemisinin and Procyanidins loaded multifunctional nanocomplexes alleviate atherosclerosis via simultaneously modulating lipid influx and cholesterol efflux.
Fusobacterium nucleatum promotes colorectal cancer cells adhesion to endothelial cells and facilitates extravasation and metastasis by inducing ALPK1/NF-κB/ICAM1 axis.
Effects of whole-life exposure to low-dose cadmium with post-weaning high-fat diet on offspring testes in a male mouse model.
Th22 cells induce Müller cell activation via the Act1/TRAF6 pathway in diabetic retinopathy.
The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).
The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.
Overexpression of integrin β(2) improves migration and engraftment of adipose-derived stem cells and augments angiogenesis in myocardial infarction.
Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells.
Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.
Dauricine Attenuates Vascular Endothelial Inflammation Through Inhibiting NF-κB Pathway.
Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance.
The role of AMP-activated protein kinase α1-mediated endoplasmic reticulum stress in alleviating the toxic effect of uremic toxin indoxyl sulfate on vascular endothelial cells by Klotho.
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
Prostaglandin E1 attenuates AngII-induced cardiac hypertrophy via EP3 receptor activation and Netrin-1upregulation.
Neutrophil-Derived Proteases Contribute to the Pathogenesis of Early Diabetic Retinopathy.
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis.
Fibroblast Growth Factor Type 1 Ameliorates High-Glucose-Induced Oxidative Stress and Neuroinflammation in Retinal Pigment Epithelial Cells and a Streptozotocin-Induced Diabetic Rat Model.
LncRNA LPAL2/miR-1287-5p/EGFR Axis Modulates TED-Derived Orbital Fibroblast Activation Through Cell Adhesion Factors.
Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis.
ICAM-1 Activates Platelets and Promotes Endothelial Permeability through VE-Cadherin after Insufficient Radiofrequency Ablation.
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway.
Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis.
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Extracellular vesicles secreted from mesenchymal stem cells exert anti-apoptotic and anti-inflammatory effects via transmitting microRNA-18b in rats with diabetic retinopathy.
Human umbilical cord mesenchymal stem cells regulate CD54 and CD105 in vascular endothelial cells and suppress inflammation in Kawasaki disease.
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway.
Ginsenoside Rg3 Alleviates ox-LDL Induced Endothelial Dysfunction and Prevents Atherosclerosis in ApoE(-/-) Mice by Regulating PPARγ/FAK Signaling Pathway.
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Genetic Deletion of Vasohibin-2 Exacerbates Ischemia-Reperfusion-Induced Acute Kidney Injury.
Heme Oxygenase Protects against Placental Vascular Inflammation and Abortion by the Alarmin Heme in Mice.
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy.
Endothelial microvesicles induced by physiological cyclic stretch inhibit ICAM1-Dependent leukocyte adhesion.
Engineered Cell-Derived Microparticles Bi(2)Se(3)/DOX@MPs for Imaging Guided Synergistic Photothermal/Low-Dose Chemotherapy of Cancer.
PP2A alleviates oxidized LDL-induced endothelial dysfunction by regulating LOX-1/ROS/MAPK axis.
Neferine suppresses vascular endothelial inflammation by inhibiting the NF-κB signaling pathway.
Bone marrow mesenchymal stem cells combine with normothermic machine perfusion to improve rat donor liver quality-the important role of hepatic microcirculation in donation after circulatory death.
DNA damage/cGAS-triggered up-regulation of MALAT1 promotes undesirable inflammatory responses in radiotherapy of cancer.
Kallistatin correlates with inflammation in abdominal aortic aneurysm and suppresses its formation in mice.
PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis.
Antihypertensive effects of Trichiurus lepturus myosin hydrolysate in spontaneously hypertensive rats.
The β-galactoside α2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation.
Simvastatin promotes endothelial dysfunction by activating the Wnt/β‑catenin pathway under oxidative stress.
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells.
Propofol attenuates the adhesion of tumor and endothelial cells through inhibiting glycolysis in human umbilical vein endothelial cells.
MiR-326 Inhibits Inflammation and Promotes Autophagy in Silica-Induced Pulmonary Fibrosis through Targeting TNFSF14 and PTBP1.
Role of allograft inflammatory factor-1 in the regulation of inflammation and oxidative stress in primary peritoneal mesothelial cells.
Chrysin Suppresses Vascular Endothelial Inflammation via Inhibiting the NF-κB Signaling Pathway.
Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice.
Sphingomyelin Synthase 2 Promotes Endothelial Dysfunction by Inducing Endoplasmic Reticulum Stress.
LXA4 ameliorates cerebrovascular endothelial dysfunction by reducing acute inflammation after subarachnoid hemorrhage in rats.
Aqueous extract of Salvia miltiorrhiza Bunge-Radix Puerariae herb pair ameliorates diabetic vascular injury by inhibiting oxidative stress in streptozotocin-induced diabetic rats.
Low-Dose IFNγ Induces Tumor Cell Stemness in Tumor Microenvironment of Non-Small Cell Lung Cancer.
Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells.
Injectable extracellular vesicle-released self-assembling peptide nanofiber hydrogel as an enhanced cell-free therapy for tissue regeneration.
Pharmacological blockage of ICAM-1 improves angiotensin II-induced cardiac remodeling by inhibiting adhesion of LFA-1(+) monocytes.
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
The expression of cerebrospinal fluid exosomal miR-630 plays an important role in the dysfunction of endothelial cells after subarachnoid hemorrhage.
Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy.
Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy.
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α.
The Role of Alpha-Lipoic Acid in the Pathomechanism of Acute Ischemic Stroke.
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Expression of P2X1 receptors in somatostatin-containing cells in mouse gastrointestinal tract and pancreatic islets of both mouse and human.
S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.
Complement component 3a receptor deficiency attenuates chronic stress-induced monocyte infiltration and depressive-like behavior.
Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy.
GATA4 regulates angiogenesis and persistence of inflammation in rheumatoid arthritis.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Hypothermic oxygenated perfusion (HOPE) attenuates ischemia/reperfusion injury in the liver through inhibition of the TXNIP/NLRP3 inflammasome pathway in a rat model of donation after cardiac death.
Effects of Tumor Necrosis Factor α (TNF-α) and Interleukina 10 (IL-10) on Intercellular Cell Adhesion Molecule-1 (ICAM-1) and Cluster of Differentiation 31 (CD31) in Human Coronary Artery Endothelial Cells.
Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats.
SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells.
Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity.
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.
Up-regulated lnc-SNHG1 contributes to osteosarcoma progression through sequestration of miR-577 and activation of WNT2B/Wnt/β-catenin pathway.
A combination of ultrasound-targeted microbubble destruction with transplantation of bone marrow mesenchymal stem cells promotes recovery of acute liver injury.
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
PAMs ameliorates the imiquimod-induced psoriasis-like skin disease in mice by inhibition of translocation of NF-κB and production of inflammatory cytokines.
Human cytotoxic T-lymphocyte membrane-camouflaged nanoparticles combined with low-dose irradiation: a new approach to enhance drug targeting in gastric cancer.
Macrophage-stimulated microRNA expression in mural cells promotes transplantation-induced neointima formation.
A new approach to transfect NF-κB decoy oligodeoxynucleotides into the periodontal tissue using the ultrasound-microbubble method.
Geniposide reduces development of streptozotocin-induced diabetic nephropathy via regulating nuclear factor-kappa B signaling pathways.
Low molecular weight fucoidan modulates P-selectin and alleviates diabetic nephropathy.
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Tetrachlorobenzoquinone Stimulates NLRP3 Inflammasome-Mediated Post-Translational Activation and Secretion of IL-1β in the HUVEC Endothelial Cell Line.
A simple multi-well stretching device to induce inflammatory responses of vascular endothelial cells.
Expression of Sox2 in breast cancer cells promotes the recruitment of M2 macrophages to tumor microenvironment.
Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway.
C-type natriuretic peptide attenuates LPS-induced endothelial activation: involvement of p38, Akt, and NF-κB pathways.
Up-regulated isocitrate dehydrogenase 1 suppresses proliferation, migration and invasion in osteosarcoma: in vitro and in vivo.
MyD88-dependent pathways in leukocytes affect the retina in diabetes.
Leukocytes regulate retinal capillary degeneration in the diabetic mouse via generation of leukotrienes.
The mobilization, recruitment and contribution of bone marrow-derived endothelial progenitor cells to the tumor neovascularization occur at an early stage and throughout the entire process of hepatocellular carcinoma growth.
Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis.
PP2A contributes to endothelial death in high glucose: inhibition by benfotiamine.
Combining carbon ion radiotherapy and local injection of α-galactosylceramide-pulsed dendritic cells inhibits lung metastases in an in vivo murine model.
Zhang X, Tan Y, Li T, Tan D, Fu B, Yang M, Chen Y, Cao M, Xuan C, Du Q, Hu R, Wang Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Sep;76:101112
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Sep;76:101112
Esaxerenone Inhibits Interferon-γ Induced Pyroptosis of Macrophages in the Lungs of Aldosterone-treated Mice.
Chang J, Gao X, Yang F, Qiang P, Fan L, Liu Z, Shimosawa T, Xu Q, Chang Y
Inflammation 2024 May 7;
Inflammation 2024 May 7;
REXO2 up-regulation is positively correlated with poor prognosis and tumor immune infiltration in hepatocellular carcinoma.
Zhang T, Zhang R, Zhang Z, Li D, Guo X, Zhang Z, Zhu X, Tan S
International immunopharmacology 2024 Mar 30;130:111740
International immunopharmacology 2024 Mar 30;130:111740
Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids.
Dao L, You Z, Lu L, Xu T, Sarkar AK, Zhu H, Liu M, Calandrelli R, Yoshida G, Lin P, Miao Y, Mierke S, Kalva S, Zhu H, Gu M, Vadivelu S, Zhong S, Huang LF, Guo Z
Cell stem cell 2024 Jun 6;31(6):818-833.e11
Cell stem cell 2024 Jun 6;31(6):818-833.e11
Quercetin attenuates inflammation in rosacea by directly targeting p65 and ICAM-1.
Meng X, Li Y, Wang F, Li T, Wang B, Wang Q, Long J, Xie H, Zhang Y, Li J
Life sciences 2024 Jun 15;347:122675
Life sciences 2024 Jun 15;347:122675
Ginsenoside Rg1 alleviates vascular remodeling in hypoxia-induced pulmonary hypertension mice through the calpain-1/STAT3 signaling pathway.
Ran C, Lu M, Zhao F, Hao Y, Guo X, Li Y, Su Y, Wang H
Journal of ginseng research 2024 Jul;48(4):405-416
Journal of ginseng research 2024 Jul;48(4):405-416
Ciliary neurotrophic factor promotes the development of homocysteine-induced vascular endothelial injury through inflammation mediated by the JAK2/STAT3 signaling pathway.
Zhang L, Xiang Y, Cao C, Tan J, Li F, Yang X
Experimental cell research 2024 Jul 1;440(1):114103
Experimental cell research 2024 Jul 1;440(1):114103
iNOS inhibitor S-methylisothiourea alleviates smoke inhalation-induced acute lung injury by suppressing inflammation and macrophage infiltration.
Shi Y, Cao Y, Han X, Xie L, Xiao K
International immunopharmacology 2024 Jan 5;126:111097
International immunopharmacology 2024 Jan 5;126:111097
The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Wang C, Chen H, Su H, Sheng Q, Lang Y, Yu Q, Lv Z, Wang R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb;38(2):e23446
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Feb;38(2):e23446
Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression.
Liu Y, He J, Li M, Ren K, Zhao Z
ACS applied materials & interfaces 2024 Feb 14;16(6):6879-6893
ACS applied materials & interfaces 2024 Feb 14;16(6):6879-6893
Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs.
Kersey AL, Cheng DY, Deo KA, Dubell CR, Wang TC, Jaiswal MK, Kim MH, Murali A, Hargett SE, Mallick S, Lele TP, Singh I, Gaharwar AK
Biomaterials 2024 Apr;306:122473
Biomaterials 2024 Apr;306:122473
TMAO promotes vascular endothelial cell pyroptosis via the LPEAT-mitophagy pathway.
Chen Y, Yuan C, Qin W, Yu B, Wei D, Wu P
Biochemical and biophysical research communications 2024 Apr 9;703:149667
Biochemical and biophysical research communications 2024 Apr 9;703:149667
Increased expression of cell adhesion molecules in myofasciitis.
Ma X, Gao H, Xu L, Bi Z, Ji S, Bu B
Frontiers in neurology 2023;14:1113404
Frontiers in neurology 2023;14:1113404
Sclareol attenuates liver fibrosis through SENP1-mediated VEGFR2 SUMOylation and inhibition of downstream STAT3 signaling.
Ge MX, Niu WX, Bao YY, Lu ZN, He HW
Phytotherapy research : PTR 2023 Sep;37(9):3898-3912
Phytotherapy research : PTR 2023 Sep;37(9):3898-3912
Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF.
Fan R, Su L, Zhang H, Jiang Y, Yu Z, Zhang X, Li X
Journal of nanobiotechnology 2023 Sep 8;21(1):327
Journal of nanobiotechnology 2023 Sep 8;21(1):327
ERβ promoted invadopodia formation-mediated non-small cell lung cancer metastasis via the ICAM1/p-Src/p-Cortactin signaling pathway.
Wang Y, Qiu W, Chen J, Meng W, Zhao R, Lin W, Mei P, Diao M, Xiao H, Liao Y
International journal of cancer 2023 Sep 15;153(6):1287-1299
International journal of cancer 2023 Sep 15;153(6):1287-1299
Salvianolic acid B inhibits atherosclerosis and TNF-α-induced inflammation by regulating NF-κB/NLRP3 signaling pathway.
Zhao Y, Shao C, Zhou H, Yu L, Bao Y, Mao Q, Yang J, Wan H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155002
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155002
Chimpanzee adenovirus-mediated multiple gene therapy for age-related macular degeneration.
Wei-Zhang S, Cui B, Xing M, Liu J, Guo Y, He K, Bai T, Dong X, Lei Y, Zhou W, Zhou H, Liu S, Wang X, Zhou D, Yan H
iScience 2023 Oct 20;26(10):107939
iScience 2023 Oct 20;26(10):107939
Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions.
Tiruppathi C, Wang DM, Ansari MO, Bano S, Tsukasaki Y, Mukhopadhyay A, Joshi JC, Loch C, Niessen HWM, Malik AB
Nature communications 2023 Oct 18;14(1):6582
Nature communications 2023 Oct 18;14(1):6582
Biomimetic nanoparticles loaded lutein functionalized by macrophage membrane for targeted amelioration pressure overload-induced cardiac fibrosis.
Guo T, Chen L, Li F, Cao Y, Li D, Xiong Q, Ling Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115579
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115579
Tissue-derived exosome proteomics identifies promising diagnostic biomarkers for esophageal cancer.
Rao D, Lu H, Wang X, Lai Z, Zhang J, Tang Z
eLife 2023 Nov 15;12
eLife 2023 Nov 15;12
Endogenous FGF1 Deficiency Aggravates Doxorubicin-Induced Hepatotoxicity.
Gu C, Liu Z, Li Y, Yi M, Wang S, Fan X, Sun D, Zhang C, Yan X, Wu G
Toxics 2023 Nov 12;11(11)
Toxics 2023 Nov 12;11(11)
ICAM-1-suPAR-CD11b Axis Is a Novel Therapeutic Target for Metastatic Triple-Negative Breast Cancer.
Li D, Hemati H, Park Y, Taftaf R, Zhang Y, Liu J, Cristofanilli M, Liu X
Cancers 2023 May 12;15(10)
Cancers 2023 May 12;15(10)
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.
Fang J, Zhang Y, Huang C, Lu R, Yu J, Chen R, Wang Y, Zhao X, Yu J, Huang J
Oncogene 2023 Mar;42(14):1058-1071
Oncogene 2023 Mar;42(14):1058-1071
PbO nanoparticles increase the expression of ICAM-1 and VCAM-1 by increasing reactive oxygen species production in choroid plexus.
Wang W, Li S, Wang X, Wang J, Zhang Y
Environmental science and pollution research international 2023 Mar;30(14):40162-40173
Environmental science and pollution research international 2023 Mar;30(14):40162-40173
The Effect of Cholesterol Efflux on Endothelial Dysfunction Caused by Oxidative Stress.
Ye H, Liu Q, Wang Y, Zhen X, Yan N
International journal of molecular sciences 2023 Mar 21;24(6)
International journal of molecular sciences 2023 Mar 21;24(6)
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Qiu Q, Guo G, Guo X, Hu X, Yu T, Liu G, Zhang H, Chen Y, She J
Biomedicines 2023 Mar 13;11(3)
Biomedicines 2023 Mar 13;11(3)
Sitagliptin therapy improves myocardial perfusion and arteriolar collateralization in chronically ischemic myocardium: A pilot study.
Sabe SA, Harris DD, Broadwin M, Sabra M, Xu CM, Banerjee D, Abid MR, Sellke FW
Physiological reports 2023 Jun;11(11):e15744
Physiological reports 2023 Jun;11(11):e15744
Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice.
Pei Z, Zhou R, Yao W, Dong S, Liu Y, Gao Z
iScience 2023 Jul 21;26(7):107080
iScience 2023 Jul 21;26(7):107080
Skewing cPLA(2)α activity toward oxoeicosanoid production promotes neutrophil N2 polarization, wound healing, and the response to sepsis.
Maus KD, Stephenson DJ, Macknight HP, Vu NT, Hoeferlin LA, Kim M, Diegelmann RF, Xie X, Chalfant CE
Science signaling 2023 Jul 11;16(793):eadd6527
Science signaling 2023 Jul 11;16(793):eadd6527
Disturbed Flow-Facilitated Margination and Targeting of Nanodisks Protect against Atherosclerosis.
Zhao CR, Li J, Jiang ZT, Zhu JJ, Zhao JN, Yang QR, Yao W, Pang W, Li N, Yu M, Gan Y, Zhou J
Small (Weinheim an der Bergstrasse, Germany) 2023 Jan;19(2):e2204694
Small (Weinheim an der Bergstrasse, Germany) 2023 Jan;19(2):e2204694
Fyn deficiency inhibits oxidative stress by decreasing c-Cbl-mediated ubiquitination of Sirt1 to attenuate diabetic renal fibrosis.
Li S, Lin Z, Xiao H, Xu Z, Li C, Zeng J, Xie X, Deng L, Huang H
Metabolism: clinical and experimental 2023 Feb;139:155378
Metabolism: clinical and experimental 2023 Feb;139:155378
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
Lin D, Sun Q, Liu Z, Pan J, Zhu J, Wang S, Jia S, Zheng M, Li X, Gong F
Free radical biology & medicine 2023 Feb 1;195:199-218
Free radical biology & medicine 2023 Feb 1;195:199-218
KPNA2 Silencing, Regulated by E3 Ubiquitin Ligase FBXW7, Alleviates Endothelial Dysfunction and Inflammation Through Inhibiting the Nuclear Translocation of p65 and IRF3: A Possible Therapeutic Approach for Atherosclerosis.
Xing Z, Zhen Y, Chen J, Du M, Li D, Liu R, Zheng J
Inflammation 2023 Dec;46(6):2071-2088
Inflammation 2023 Dec;46(6):2071-2088
Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increased Mitochondrial Fission In Vitro and Atherosclerosis in High-Fat-Diet-Fed ApoE(-/-) Mice.
Ren J, Liu J, Zhang J, Hu X, Cui Y, Wei X, Ma Y, Li X, Zhao Y
International journal of molecular sciences 2023 Dec 23;25(1)
International journal of molecular sciences 2023 Dec 23;25(1)
Connexin32 Promotes the Activation of Foxo3a to Ameliorate Diabetic Nephropathy via Inhibiting the Polyubiquitination and Degradation of Sirt1.
Li S, Xiao H, Sun X, Chen Z, Lin Z, Li C, Zeng J, Xu Z, Cheng Y, Huang H
Antioxidants & redox signaling 2023 Aug;39(4-6):241-261
Antioxidants & redox signaling 2023 Aug;39(4-6):241-261
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Wang X, Zhou Y, Sun Q, Zhang Q, Zhou H, Zhang J, Du Y, Wang Y, Yuan K, Xu L, Zhang M, Yan D, Zeng L, Xu K, Sang W
Transplantation and cellular therapy 2023 Aug;29(8):492.e1-492.e10
Transplantation and cellular therapy 2023 Aug;29(8):492.e1-492.e10
Protective Role of Vitamin K3 on SARS-CoV-2 Structural Protein-Induced Inflammation and Cell Death.
Zhan Y, Zha D, Lin H, Mao X, Yang L, Huang H, He Z, Zhou S, Xu F, Qian Y, Liu Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 3;16(8)
Pharmaceuticals (Basel, Switzerland) 2023 Aug 3;16(8)
Caspase-1-mediated extracellular vesicles derived from pyroptotic alveolar macrophages promote inflammation in acute lung injury.
Qin X, Zhou Y, Jia C, Chao Z, Qin H, Liang J, Liu X, Liu Z, Sun T, Yuan Y, Zhang H
International journal of biological sciences 2022;18(4):1521-1538
International journal of biological sciences 2022;18(4):1521-1538
Interaction of RARRES1 with ICAM1 modulates macrophages to suppress the progression of kidney renal clear cell carcinoma.
Geng X, Chi K, Liu C, Fu Z, Wang X, Meng L, Wang H, Cai G, Chen X, Hong Q
Frontiers in immunology 2022;13:982045
Frontiers in immunology 2022;13:982045
Circulating galectin-3 promotes tumor-endothelium-adhesion by upregulating ICAM-1 in endothelium-derived extracellular vesicles.
Wang L, Du DD, Zheng ZX, Shang PF, Yang XX, Sun C, Wang XY, Tang YJ, Guo XL
Frontiers in pharmacology 2022;13:979474
Frontiers in pharmacology 2022;13:979474
Momordica charantia Exosome-Like Nanoparticles Exert Neuroprotective Effects Against Ischemic Brain Injury via Inhibiting Matrix Metalloproteinase 9 and Activating the AKT/GSK3β Signaling Pathway.
Cai H, Huang LY, Hong R, Song JX, Guo XJ, Zhou W, Hu ZL, Wang W, Wang YL, Shen JG, Qi SH
Frontiers in pharmacology 2022;13:908830
Frontiers in pharmacology 2022;13:908830
Plasma Exosomes Transfer miR-885-3p Targeting the AKT/NFκB Signaling Pathway to Improve the Sensitivity of Intravenous Glucocorticoid Therapy Against Graves Ophthalmopathy.
Sun J, Wei J, Zhang Y, Li J, Li J, Yan J, Guo M, Han J, Qiao H
Frontiers in immunology 2022;13:819680
Frontiers in immunology 2022;13:819680
ICAM-1-related noncoding RNA accelerates atherosclerosis by amplifying NF-κB signaling.
Ding S, Liu J, Han X, Ding W, Liu Z, Zhu Y, Zhan W, Wan Y, Gai S, Hou J, Wang X, Wu Y, Wu A, Li CY, Zheng Z, Tian XL, Cao H
Journal of molecular and cellular cardiology 2022 Sep;170:75-86
Journal of molecular and cellular cardiology 2022 Sep;170:75-86
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.
Zhou Y, Lu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113291
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113291
Macrophage-derived exosomal miR-4532 promotes endothelial cells injury by targeting SP1 and NF-κB P65 signalling activation.
Liu P, Wang S, Wang G, Zhao M, Du F, Li K, Wang L, Wu H, Chen J, Yang Y, Su G
Journal of cellular and molecular medicine 2022 Oct;26(20):5165-5180
Journal of cellular and molecular medicine 2022 Oct;26(20):5165-5180
Lack of NPR1 Increases Vascular Endothelial Adhesion through Induction of Integrin Beta 4.
Liu H, Liu J, Long C, Chen L, Zhan W, Xiao W, Gong X, Liu M, Tian XL, Chen S
International journal of molecular sciences 2022 Oct 20;23(20)
International journal of molecular sciences 2022 Oct 20;23(20)
7-Methoxyisoflavone suppresses vascular endothelial inflammation by inhibiting the expression of endothelial adhesion molecules.
Zhu X, Peng J, Yang L, Guo Y, Wang P, Liu K, Zhu J, Deng S, Liang M
European journal of pharmacology 2022 Oct 15;933:175268
European journal of pharmacology 2022 Oct 15;933:175268
Neutrophil extracellular traps: A novel therapeutic target for intracranial hemorrhage.
Jin J, Zhao X, Li W, Wang F, Tian J, Wang N, Gao X, Zhang J, Wu J, Mang G, Ma R, Hu S
Thrombosis research 2022 Nov;219:1-13
Thrombosis research 2022 Nov;219:1-13
Triterpenoid saponins of Ilex pubescens against TNF-α induced inflammation and apoptosis in human umbilical vein endothelial cells via autophagy pathway.
Yan X, Shang X, Feng Z, Chen B, Wu Y, Zhou Y, Li Y, Zhang L
The Journal of pharmacy and pharmacology 2022 Nov 25;74(12):1749-1757
The Journal of pharmacy and pharmacology 2022 Nov 25;74(12):1749-1757
Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis.
Li Y, Zhang H, Chen C, Qiao K, Li Z, Han J, Han X, Li K, Lai K, Liu N, Li A, Xiao N, Zhang Y, Zhao X, Gao W, Zhang Y, Liu H, Sun T
Advanced materials (Deerfield Beach, Fla.) 2022 May;34(19):e2108476
Advanced materials (Deerfield Beach, Fla.) 2022 May;34(19):e2108476
LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.
Zhu W, Peng F, Cui X, Li J, Sun C
Clinical immunology (Orlando, Fla.) 2022 May;238:109006
Clinical immunology (Orlando, Fla.) 2022 May;238:109006
Tumor endothelial cell-induced CD8(+) T-cell exhaustion via GPNMB in hepatocellular carcinoma.
Sakano Y, Noda T, Kobayashi S, Sasaki K, Iwagami Y, Yamada D, Tomimaru Y, Akita H, Gotoh K, Takahashi H, Asaoka T, Tanemura M, Wada H, Doki Y, Eguchi H
Cancer science 2022 May;113(5):1625-1638
Cancer science 2022 May;113(5):1625-1638
Porcine Epidemic Diarrhea Virus Infection Disrupts the Nasal Endothelial Barrier To Favor Viral Dissemination.
Li J, Li Y, Liu P, Wang X, Ma Y, Zhong Q, Yang Q
Journal of virology 2022 May 11;96(9):e0038022
Journal of virology 2022 May 11;96(9):e0038022
miR-1290 promotes IL-8-mediated vascular endothelial cell adhesion by targeting GSK-3β.
Xu H, Cui Y, Liu X, Zheng X, Liu J, Hu X, Gao F, Hu X, Li M, Wei X, Gao Y, Zhao Y
Molecular biology reports 2022 Mar;49(3):1871-1882
Molecular biology reports 2022 Mar;49(3):1871-1882
Neutrophil membrane-mimicking nanodecoys with intrinsic anti-inflammatory properties alleviate sepsis-induced acute liver injury and lethality in a mouse endotoxemia model.
Xiao Y, Ren C, Chen G, Shang P, Song X, You G, Yan S, Yao Y, Zhou H
Materials today. Bio 2022 Mar;14:100244
Materials today. Bio 2022 Mar;14:100244
Dihydrohomoplantagin and Homoplantaginin, Major Flavonoid Glycosides from Salvia plebeia R. Br. Inhibit oxLDL-Induced Endothelial Cell Injury and Restrict Atherosclerosis via Activating Nrf2 Anti-Oxidation Signal Pathway.
Meng N, Chen K, Wang Y, Hou J, Chu W, Xie S, Yang F, Sun C
Molecules (Basel, Switzerland) 2022 Mar 19;27(6)
Molecules (Basel, Switzerland) 2022 Mar 19;27(6)
Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma.
Li Z, Li Y, Li N, Shen L, Liu A
Clinical science (London, England : 1979) 2022 Jun 17;136(11):895-909
Clinical science (London, England : 1979) 2022 Jun 17;136(11):895-909
Artemisinin and Procyanidins loaded multifunctional nanocomplexes alleviate atherosclerosis via simultaneously modulating lipid influx and cholesterol efflux.
Zhou H, You P, Liu H, Fan J, Tong C, Yang A, Jiang Y, Liu B
Journal of controlled release : official journal of the Controlled Release Society 2022 Jan;341:828-843
Journal of controlled release : official journal of the Controlled Release Society 2022 Jan;341:828-843
Fusobacterium nucleatum promotes colorectal cancer cells adhesion to endothelial cells and facilitates extravasation and metastasis by inducing ALPK1/NF-κB/ICAM1 axis.
Zhang Y, Zhang L, Zheng S, Li M, Xu C, Jia D, Qi Y, Hou T, Wang L, Wang B, Li A, Chen S, Si J, Zhuo W
Gut microbes 2022 Jan-Dec;14(1):2038852
Gut microbes 2022 Jan-Dec;14(1):2038852
Effects of whole-life exposure to low-dose cadmium with post-weaning high-fat diet on offspring testes in a male mouse model.
Xiong L, Zhou B, Young JL, Xu J, Wintergerst K, Cai L
Chemico-biological interactions 2022 Feb 1;353:109797
Chemico-biological interactions 2022 Feb 1;353:109797
Th22 cells induce Müller cell activation via the Act1/TRAF6 pathway in diabetic retinopathy.
Wang Y, Yu H, Li J, Liu W, Yu S, Lv P, Zhao L, Wang X, Zuo Z, Liu X
Cell and tissue research 2022 Dec;390(3):367-383
Cell and tissue research 2022 Dec;390(3):367-383
The ubiquitination of CKIP-1 mediated by Src aggravates diabetic renal fibrosis (original article).
Yang Y, Xiao H, Lin Z, Chen R, Li S, Li C, Sun X, Hei Z, Gong W, Huang H
Biochemical pharmacology 2022 Dec;206:115339
Biochemical pharmacology 2022 Dec;206:115339
The mechanism underlying ICAM-1 and E-selectin-mediated hypertriglyceridemic pancreatitis-associated lung injury.
Yu R, Hou C, Peng Y, Zhu X, Shi C, Huang D, Miao Y, Li Q
Molecular immunology 2022 Dec;152:55-66
Molecular immunology 2022 Dec;152:55-66
Overexpression of integrin β(2) improves migration and engraftment of adipose-derived stem cells and augments angiogenesis in myocardial infarction.
Yuan Z, Yan K, Wang J
Annals of translational medicine 2022 Aug;10(16):863
Annals of translational medicine 2022 Aug;10(16):863
Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells.
Jun L, Lin-Lin S, Hui S
Molecular vision 2021;27:575-587
Molecular vision 2021;27:575-587
Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.
Wu Y, Liu L, Shen X, Liu W, Ma R
Cancer management and research 2021;13:559-570
Cancer management and research 2021;13:559-570
Dauricine Attenuates Vascular Endothelial Inflammation Through Inhibiting NF-κB Pathway.
Hu J, Chen R, An J, Wang Y, Liang M, Huang K
Frontiers in pharmacology 2021;12:758962
Frontiers in pharmacology 2021;12:758962
Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance.
Zhao M, Wang Y, Li L, Liu S, Wang C, Yuan Y, Yang G, Chen Y, Cheng J, Lu Y, Liu J
Theranostics 2021;11(4):1845-1863
Theranostics 2021;11(4):1845-1863
The role of AMP-activated protein kinase α1-mediated endoplasmic reticulum stress in alleviating the toxic effect of uremic toxin indoxyl sulfate on vascular endothelial cells by Klotho.
Chen C, Wu L, Xie C, Zhao X, Mao H, Xing C
Journal of applied toxicology : JAT 2021 Sep;41(9):1446-1455
Journal of applied toxicology : JAT 2021 Sep;41(9):1446-1455
Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.
Wang TD, Xu SL, Yu ZY, Ni SB, Zhang C, Jiao ZX
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
Chinese journal of integrative medicine 2021 Oct;27(10):760-766
Prostaglandin E1 attenuates AngII-induced cardiac hypertrophy via EP3 receptor activation and Netrin-1upregulation.
Shen Y, Wang X, Yuan R, Pan X, Yang X, Cai J, Li Y, Yin A, Xiao Q, Ji Q, Li Y, He B, Shen L
Journal of molecular and cellular cardiology 2021 Oct;159:91-104
Journal of molecular and cellular cardiology 2021 Oct;159:91-104
Neutrophil-Derived Proteases Contribute to the Pathogenesis of Early Diabetic Retinopathy.
Lessieur EM, Liu H, Saadane A, Du Y, Tang J, Kiser J, Kern TS
Investigative ophthalmology & visual science 2021 Oct 4;62(13):7
Investigative ophthalmology & visual science 2021 Oct 4;62(13):7
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Zhang J, Ma X, Fan D
Foods (Basel, Switzerland) 2021 May 26;10(6)
Foods (Basel, Switzerland) 2021 May 26;10(6)
MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis.
Xie Y, Liu B, Pan J, Liu J, Li X, Li H, Qiu S, Xiang X, Zheng P, Chen J, Yuan Y, Dong Z, Zhang D
Molecular therapy. Nucleic acids 2021 Mar 5;23:76-88
Molecular therapy. Nucleic acids 2021 Mar 5;23:76-88
Fibroblast Growth Factor Type 1 Ameliorates High-Glucose-Induced Oxidative Stress and Neuroinflammation in Retinal Pigment Epithelial Cells and a Streptozotocin-Induced Diabetic Rat Model.
Huang HW, Yang CM, Yang CH
International journal of molecular sciences 2021 Jul 5;22(13)
International journal of molecular sciences 2021 Jul 5;22(13)
LncRNA LPAL2/miR-1287-5p/EGFR Axis Modulates TED-Derived Orbital Fibroblast Activation Through Cell Adhesion Factors.
Wang N, Hou SY, Qi X, Deng M, Cao JM, Tong BD, Xiong W
The Journal of clinical endocrinology and metabolism 2021 Jul 13;106(8):e2866-e2886
The Journal of clinical endocrinology and metabolism 2021 Jul 13;106(8):e2866-e2886
Hsa_circ_0007456 regulates the natural killer cell-mediated cytotoxicity toward hepatocellular carcinoma via the miR-6852-3p/ICAM-1 axis.
Shi M, Li ZY, Zhang LM, Wu XY, Xiang SH, Wang YG, Zhang YQ
Cell death & disease 2021 Jan 18;12(1):94
Cell death & disease 2021 Jan 18;12(1):94
ICAM-1 Activates Platelets and Promotes Endothelial Permeability through VE-Cadherin after Insufficient Radiofrequency Ablation.
Kong J, Yao C, Dong S, Wu S, Xu Y, Li K, Ji L, Shen Q, Zhang Q, Zhan R, Cui H, Zhou C, Niu H, Li G, Sun W, Zheng L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Feb;8(4):2002228
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Feb;8(4):2002228
MicroRNA-520c-3p suppresses vascular endothelium dysfunction by targeting RELA and regulating the AKT and NF-κB signaling pathways.
Jiao Y, Zhao D, Gao F, Hu X, Hu X, Li M, Cui Y, Wei X, Xie C, Zhao Y, Gao Y
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
Journal of physiology and biochemistry 2021 Feb;77(1):47-61
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway.
Feng Z, Wang C, Yue, Jin, Meng Q, Wu J, Sun H
Pharmaceutical biology 2021 Dec;59(1):1106-1116
Pharmaceutical biology 2021 Dec;59(1):1106-1116
Kaposi's sarcoma-associated herpesvirus vFLIP promotes MEndT to generate hybrid M/E state for tumorigenesis.
Chen W, Ding Y, Liu D, Lu Z, Wang Y, Yuan Y
PLoS pathogens 2021 Dec;17(12):e1009600
PLoS pathogens 2021 Dec;17(12):e1009600
Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy.
Wang Z, Li Y, Yao J, Yu S, Yu H, Men L, Du J
The international journal of biochemistry & cell biology 2021 Dec;141:106111
The international journal of biochemistry & cell biology 2021 Dec;141:106111
Extracellular vesicles secreted from mesenchymal stem cells exert anti-apoptotic and anti-inflammatory effects via transmitting microRNA-18b in rats with diabetic retinopathy.
Xu Z, Tian N, Li S, Li K, Guo H, Zhang H, Jin H, An M, Yu X
International immunopharmacology 2021 Dec;101(Pt B):108234
International immunopharmacology 2021 Dec;101(Pt B):108234
Human umbilical cord mesenchymal stem cells regulate CD54 and CD105 in vascular endothelial cells and suppress inflammation in Kawasaki disease.
Chen T, Xu T, Cheng M, Fang H, Shen X, Tang Z, Zhao J
Experimental cell research 2021 Dec 15;409(2):112941
Experimental cell research 2021 Dec 15;409(2):112941
Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells.
Zhou X, Liu J, Yang S, Su Y, Meng Z, Hu Y
Clinics (Sao Paulo, Brazil) 2020;75:e1865
Clinics (Sao Paulo, Brazil) 2020;75:e1865
Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway.
Chen Y, Feng B, Yuan Y, Hu J, Zhao W, Jiang H, Li W, Fan Z, Du Z
Mediators of inflammation 2020;2020:6318520
Mediators of inflammation 2020;2020:6318520
Ginsenoside Rg3 Alleviates ox-LDL Induced Endothelial Dysfunction and Prevents Atherosclerosis in ApoE(-/-) Mice by Regulating PPARγ/FAK Signaling Pathway.
Geng J, Fu W, Yu X, Lu Z, Liu Y, Sun M, Yu P, Li X, Fu L, Xu H, Sui D
Frontiers in pharmacology 2020;11:500
Frontiers in pharmacology 2020;11:500
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Xie T, Wang C, Jin Y, Meng Q, Liu Q, Wu J, Sun H
Frontiers in pharmacology 2020;11:1034
Frontiers in pharmacology 2020;11:1034
Ketamine attenuates high-glucose-mediated endothelial inflammation in human umbilical vein endothelial cells.
Wang T, Zhu H, Hou Y, Duan W, Meng F, Liu Y
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Canadian journal of physiology and pharmacology 2020 Mar;98(3):156-161
Genetic Deletion of Vasohibin-2 Exacerbates Ischemia-Reperfusion-Induced Acute Kidney Injury.
Miyake H, Tanabe K, Tanimura S, Nakashima Y, Morioka T, Masuda K, Sugiyama H, Sato Y, Wada J
International journal of molecular sciences 2020 Jun 26;21(12)
International journal of molecular sciences 2020 Jun 26;21(12)
Heme Oxygenase Protects against Placental Vascular Inflammation and Abortion by the Alarmin Heme in Mice.
Suttorp CM, van Rheden REM, van Dijk NWM, Helmich MPAC, Kuijpers-Jagtman AM, Wagener FADTG
International journal of molecular sciences 2020 Jul 29;21(15)
International journal of molecular sciences 2020 Jul 29;21(15)
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Yang F, Li S, Cheng Y, Li J, Han X
Life sciences 2020 Jul 1;252:117611
Life sciences 2020 Jul 1;252:117611
Gentiopicroside activates the bile acid receptor Gpbar1 (TGR5) to repress NF-kappaB pathway and ameliorate diabetic nephropathy.
Xiao H, Sun X, Liu R, Chen Z, Lin Z, Yang Y, Zhang M, Liu P, Quan S, Huang H
Pharmacological research 2020 Jan;151:104559
Pharmacological research 2020 Jan;151:104559
Endothelial microvesicles induced by physiological cyclic stretch inhibit ICAM1-Dependent leukocyte adhesion.
Zhuang F, Shi Q, Wang WB, Bao H, Yan J, Gao S, Liu Z, Jiang ZL, Qi YX
Experimental cell research 2020 Jan 1;386(1):111710
Experimental cell research 2020 Jan 1;386(1):111710
Engineered Cell-Derived Microparticles Bi(2)Se(3)/DOX@MPs for Imaging Guided Synergistic Photothermal/Low-Dose Chemotherapy of Cancer.
Wang D, Yao Y, He J, Zhong X, Li B, Rao S, Yu H, He S, Feng X, Xu T, Yang B, Yong T, Gan L, Hu J, Yang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Feb;7(3):1901293
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Feb;7(3):1901293
PP2A alleviates oxidized LDL-induced endothelial dysfunction by regulating LOX-1/ROS/MAPK axis.
Xu K, Liu X, Yin D, Ren G, Zhao Y
Life sciences 2020 Feb 15;243:117270
Life sciences 2020 Feb 15;243:117270
Neferine suppresses vascular endothelial inflammation by inhibiting the NF-κB signaling pathway.
Zhong Y, He S, Huang K, Liang M
Archives of biochemistry and biophysics 2020 Dec 15;696:108595
Archives of biochemistry and biophysics 2020 Dec 15;696:108595
Bone marrow mesenchymal stem cells combine with normothermic machine perfusion to improve rat donor liver quality-the important role of hepatic microcirculation in donation after circulatory death.
Yang L, Cao H, Sun D, Hou B, Lin L, Shen ZY, Song HL
Cell and tissue research 2020 Aug;381(2):239-254
Cell and tissue research 2020 Aug;381(2):239-254
DNA damage/cGAS-triggered up-regulation of MALAT1 promotes undesirable inflammatory responses in radiotherapy of cancer.
Yuan C, Wang D, Zhang N, Wang Z, Yang F, He J, Sun R, Yang X, Hu J, Wu M
Biochemical and biophysical research communications 2020 Aug 6;528(4):746-752
Biochemical and biophysical research communications 2020 Aug 6;528(4):746-752
Kallistatin correlates with inflammation in abdominal aortic aneurysm and suppresses its formation in mice.
He Y, Han Y, Xing J, Zhai X, Wang S, Xin S, Zhang J
Cardiovascular diagnosis and therapy 2020 Apr;10(2):107-123
Cardiovascular diagnosis and therapy 2020 Apr;10(2):107-123
PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis.
Ye S, Chen Q, Jiang N, Liang X, Li J, Zong R, Huang C, Qiu Y, Ma JX, Liu Z
Investigative ophthalmology & visual science 2020 Apr 9;61(4):15
Investigative ophthalmology & visual science 2020 Apr 9;61(4):15
Antihypertensive effects of Trichiurus lepturus myosin hydrolysate in spontaneously hypertensive rats.
Fu W, Wang P, Wu H, Zhang Z, Zeng H, Zhang Y, Zheng B, Hu J
Food & function 2020 Apr 30;11(4):3645-3656
Food & function 2020 Apr 30;11(4):3645-3656
The β-galactoside α2,6-sialyltranferase 1 (ST6GAL1) inhibits the colorectal cancer metastasis by stabilizing intercellular adhesion molecule-1 via sialylation.
Zhou L, Zhang S, Zou X, Lu J, Yang X, Xu Z, Shan A, Jia W, Liu F, Yan X, Su H, Liang T, Zheng M, Zhang Y, Feng B
Cancer management and research 2019;11:6185-6199
Cancer management and research 2019;11:6185-6199
Simvastatin promotes endothelial dysfunction by activating the Wnt/β‑catenin pathway under oxidative stress.
He Z, Du X, Wu Y, Hua L, Wan L, Yan N
International journal of molecular medicine 2019 Oct;44(4):1289-1298
International journal of molecular medicine 2019 Oct;44(4):1289-1298
Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.
Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, Liu K, Sun H
Pharmacological research 2019 Oct;148:104414
Pharmacological research 2019 Oct;148:104414
Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells.
Zhang L, Wang F, Zhang Q, Liang Q, Wang S, Xian M, Wang F
International journal of molecular sciences 2019 Oct 29;20(21)
International journal of molecular sciences 2019 Oct 29;20(21)
Propofol attenuates the adhesion of tumor and endothelial cells through inhibiting glycolysis in human umbilical vein endothelial cells.
Qi J, Wu Q, Zhu X, Zhang S, Chen X, Chen W, Sun Z, Zhu M, Miao C
Acta biochimica et biophysica Sinica 2019 Nov 18;51(11):1114-1122
Acta biochimica et biophysica Sinica 2019 Nov 18;51(11):1114-1122
MiR-326 Inhibits Inflammation and Promotes Autophagy in Silica-Induced Pulmonary Fibrosis through Targeting TNFSF14 and PTBP1.
Xu T, Yan W, Wu Q, Xu Q, Yuan J, Li Y, Li P, Pan H, Ni C
Chemical research in toxicology 2019 Nov 18;32(11):2192-2203
Chemical research in toxicology 2019 Nov 18;32(11):2192-2203
Role of allograft inflammatory factor-1 in the regulation of inflammation and oxidative stress in primary peritoneal mesothelial cells.
Zhou Y, Li X, Yuan X, Hao L
Cell biology international 2019 May;43(5):495-505
Cell biology international 2019 May;43(5):495-505
Chrysin Suppresses Vascular Endothelial Inflammation via Inhibiting the NF-κB Signaling Pathway.
Zhao S, Liang M, Wang Y, Hu J, Zhong Y, Li J, Huang K, Li Y
Journal of cardiovascular pharmacology and therapeutics 2019 May;24(3):278-287
Journal of cardiovascular pharmacology and therapeutics 2019 May;24(3):278-287
Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice.
Fang Y, Tian Y, Huang Q, Wan Y, Xu L, Wang W, Pan D, Zhu S, Xie M
Journal of neuroinflammation 2019 May 9;16(1):96
Journal of neuroinflammation 2019 May 9;16(1):96
Sphingomyelin Synthase 2 Promotes Endothelial Dysfunction by Inducing Endoplasmic Reticulum Stress.
Hua L, Wu N, Zhao R, He X, Liu Q, Li X, He Z, Yu L, Yan N
International journal of molecular sciences 2019 Jun 12;20(12)
International journal of molecular sciences 2019 Jun 12;20(12)
LXA4 ameliorates cerebrovascular endothelial dysfunction by reducing acute inflammation after subarachnoid hemorrhage in rats.
Liu L, Zhang P, Zhang Z, Hu Q, He J, Liu H, Zhao J, Liang Y, He Z, Li X, Sun X, Guo Z
Neuroscience 2019 Jun 1;408:105-114
Neuroscience 2019 Jun 1;408:105-114
Aqueous extract of Salvia miltiorrhiza Bunge-Radix Puerariae herb pair ameliorates diabetic vascular injury by inhibiting oxidative stress in streptozotocin-induced diabetic rats.
Zhao W, Yuan Y, Zhao H, Han Y, Chen X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Jul;129:97-107
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Jul;129:97-107
Low-Dose IFNγ Induces Tumor Cell Stemness in Tumor Microenvironment of Non-Small Cell Lung Cancer.
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Cancer research 2019 Jul 15;79(14):3737-3748
Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells.
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BMC cardiovascular disorders 2019 Dec 30;19(1):318
BMC cardiovascular disorders 2019 Dec 30;19(1):318
Injectable extracellular vesicle-released self-assembling peptide nanofiber hydrogel as an enhanced cell-free therapy for tissue regeneration.
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Journal of controlled release : official journal of the Controlled Release Society 2019 Dec 28;316:93-104
Journal of controlled release : official journal of the Controlled Release Society 2019 Dec 28;316:93-104
Pharmacological blockage of ICAM-1 improves angiotensin II-induced cardiac remodeling by inhibiting adhesion of LFA-1(+) monocytes.
Lin QY, Lang PP, Zhang YL, Yang XL, Xia YL, Bai J, Li HH
American journal of physiology. Heart and circulatory physiology 2019 Dec 1;317(6):H1301-H1311
American journal of physiology. Heart and circulatory physiology 2019 Dec 1;317(6):H1301-H1311
Initial human T-cell leukemia virus type 1 infection of the salivary gland epithelial cells requires a biofilm-like structure.
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Virus research 2019 Aug;269:197643
Virus research 2019 Aug;269:197643
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Scientific reports 2019 Aug 8;9(1):11510
Scientific reports 2019 Aug 8;9(1):11510
Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy.
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Nature communications 2019 Aug 23;10(1):3838
Nature communications 2019 Aug 23;10(1):3838
Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy.
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Investigative ophthalmology & visual science 2019 Apr 1;60(5):1538-1546
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Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α.
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Theranostics 2018;8(3):610-626
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British journal of pharmacology 2018 May;175(9):1486-1503
British journal of pharmacology 2018 May;175(9):1486-1503
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Neurochemistry international 2018 Jun;116:1-12
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun 5;:fj201800028RR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Jun 5;:fj201800028RR
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Medical science monitor : international medical journal of experimental and clinical research 2018 Jun 27;24:4433-4439
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Experimental animals 2018 Jul 30;67(3):313-320
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SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells.
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Acta biochimica et biophysica Sinica 2018 Jul 1;50(7):635-642
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Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity.
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Life sciences 2018 Jul 1;204:55-64
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Up-regulated lnc-SNHG1 contributes to osteosarcoma progression through sequestration of miR-577 and activation of WNT2B/Wnt/β-catenin pathway.
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Biochemical and biophysical research communications 2018 Jan 1;495(1):238-245
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A new approach to transfect NF-κB decoy oligodeoxynucleotides into the periodontal tissue using the ultrasound-microbubble method.
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International journal of oral science 2017 Jun;9(2):80-86
International journal of oral science 2017 Jun;9(2):80-86
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International journal of biological macromolecules 2016 Oct;91:233-40
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
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Cancer letters 2015 Mar 28;358(2):115-123
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The mobilization, recruitment and contribution of bone marrow-derived endothelial progenitor cells to the tumor neovascularization occur at an early stage and throughout the entire process of hepatocellular carcinoma growth.
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Hepatology (Baltimore, Md.) 2011 Nov;54(5):1600-9
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American journal of physiology. Regulatory, integrative and comparative physiology 2010 Dec;299(6):R1610-7
American journal of physiology. Regulatory, integrative and comparative physiology 2010 Dec;299(6):R1610-7
Combining carbon ion radiotherapy and local injection of α-galactosylceramide-pulsed dendritic cells inhibits lung metastases in an in vivo murine model.
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International journal of radiation oncology, biology, physics 2010 Dec 1;78(5):1524-31
International journal of radiation oncology, biology, physics 2010 Dec 1;78(5):1524-31
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 10831-1-AP(ICAM-1 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ICAM-1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ICAM-1. This antibody recognizes human, mouse antigen. The ICAM-1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.