322712

antibody from BioLegend

Targeting: ICAM1 BB2, CD54

Antibody data

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Validation data

Product number: 322712 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#322712, RRID:AB_535984
Product name: APC anti-human CD54Ê
Antibody type: Monoclonal
Antigen: CD54Ê
Description: CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 on the cell surface is potently upregulated by activation; a soluble form of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.
Reactivity: Human, Simian
Host: Mouse
Conjugate: Red dye
Isotype: IgG
Vial size: 100 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

ICAM1 protein structure - 322712 shown in red.