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- Antibody Data
- Antigen structure
- References [47]
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- Validations
- Western blot [1]
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- Product number
- 10020-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10020-1-AP, RRID:AB_2121773
- Product name
- Icam-1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Icam-1 antibody (Cat. #10020-1-AP) is a rabbit polyclonal antibody that shows reactivity with mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation.
Daphnetin Preconditioning Decreases Cardiac Injury and Susceptibility to Ventricular Arrhythmia following Ischaemia-Reperfusion through the TLR4/MyD88/NF-Κb Signalling Pathway.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice.
Unveiling the CHO surfaceome: Identification of cell surface proteins reveals cell aggregation-relevant mechanisms.
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Downregulation of G3BP2 reduces atherosclerotic lesions in ApoE-/- mice.
Endothelial intercellular cell adhesion molecule 1 contributes to cell aggregate formation in CHO cells cultured in serum-free media.
Blockade of intercellular adhesion molecule-1 prevents angiotensin II-induced hypertension and vascular dysfunction.
Quasi-ultrafine particles promote cell metastasis via HMGB1-mediated cancer cell adhesion.
Injected laquinimod D-α-tocopheryl polyethylene glycol-1000 succinate polymeric micelles for the treatment of inflammatory bowel disease.
Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury.
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.
DNA damage/cGAS-triggered up-regulation of MALAT1 promotes undesirable inflammatory responses in radiotherapy of cancer.
ECM1 Prevents Activation of Transforming Growth Factor β, Hepatic Stellate Cells, and Fibrogenesis in Mice.
Low-intensity pulsed ultrasound attenuates cardiac inflammation of CVB3-induced viral myocarditis via regulation of caveolin-1 and MAPK pathways.
Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats.
Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy.
TRPC6 modulates adhesion of neutrophils to airway epithelial cells via NF-κB activation and ICAM-1 expression with ozone exposure.
Ulcerative colitis-specific delivery of keratinocyte growth factor by neutrophils-simulated liposomes facilitates the morphologic and functional recovery of the damaged colon through alleviating the inflammation.
Effects of Qingshen Granules on the Oxidative Stress-NF/kB Signal Pathway in Unilateral Ureteral Obstruction Rats.
Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival.
Control release of mitochondria-targeted antioxidant by injectable self-assembling peptide hydrogel ameliorated persistent mitochondrial dysfunction and inflammation after acute kidney injury.
Expression and significance of Sirt1 in renal allografts at the early stage of chronic renal allograft dysfunction.
Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice.
Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites.
Extracts of Zuo Jin Wan, a traditional Chinese medicine, phenocopies 5-HTR1D antagonist in attenuating Wnt/β-catenin signaling in colorectal cancer cells.
BTP2, a Store-Operated Calcium Channel Inhibitor, Attenuates Lung Ischemia-Reperfusion Injury in Rats.
In vitro assessment of deferoxamine on mesenchymal stromal cells from tumor and bone marrow.
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Puerarin Improves Diabetic Aorta Injury by Inhibiting NADPH Oxidase-Derived Oxidative Stress in STZ-Induced Diabetic Rats.
Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide.
Neuroprotective effects of Kaempferide-7-O-(4″-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats.
FTY720 Attenuates Retinal Inflammation and Protects Blood-Retinal Barrier in Diabetic Rats.
Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes.
Early treatment with atorvastatin exerts parenchymal and vascular protective effects in experimental cerebral ischaemia.
Anti-inflammation Effects of Oxysophoridine on Cerebral Ischemia-Reperfusion Injury in Mice.
Endothelial precursor cells promote angiogenesis in hepatocellular carcinoma.
Bone marrow cells: Important role on neovascularization of hepatocellular carcinoma.
Effects of pegylated interferon α2b on metastasis of hepatocellular carcinoma.
Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation.
Tumor-derived intercellular adhesion molecule-1 mediates tumor-associated leukocyte infiltration in orthotopic pancreatic xenografts.
Cyclosporin A and phenytoin modulate inflammatory responses.
Effects of sodium beta-aescin on expression of adhesion molecules and migration of neutrophils after middle cerebral artery occlusion in rats.
Koch PS, Sandorski K, Heil J, Schmid CD, Kürschner SW, Hoffmann J, Winkler M, Staniczek T, de la Torre C, Sticht C, Schledzewski K, Taketo MM, Trogisch FA, Heineke J, Géraud C, Goerdt S, Olsavszky V
Frontiers in physiology 2021;12:722394
Frontiers in physiology 2021;12:722394
Daphnetin Preconditioning Decreases Cardiac Injury and Susceptibility to Ventricular Arrhythmia following Ischaemia-Reperfusion through the TLR4/MyD88/NF-Κb Signalling Pathway.
Yang F, Jiang X, Cao H, Shuai W, Zhang L, Wang G, Quan D, Jiang X
Pharmacology 2021;106(7-8):369-383
Pharmacology 2021;106(7-8):369-383
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice.
Li D, Liu M, Li Z, Zheng G, Chen A, Zhao L, Yang P, Wei L, Chen Y, Ruan XZ
Aging and disease 2021 Jun;12(3):747-763
Aging and disease 2021 Jun;12(3):747-763
Unveiling the CHO surfaceome: Identification of cell surface proteins reveals cell aggregation-relevant mechanisms.
Klingler F, Mathias S, Schneider H, Buck T, Raab N, Zeh N, Shieh YW, Pfannstiel J, Otte K
Biotechnology and bioengineering 2021 Aug;118(8):3015-3028
Biotechnology and bioengineering 2021 Aug;118(8):3015-3028
Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.
Ma C, Feng K, Yang X, Yang Z, Wang Z, Shang Y, Fan G, Liu L, Yang S, Li X, Han J, Duan Y, Chen Y
British journal of pharmacology 2021 Apr;178(7):1620-1638
British journal of pharmacology 2021 Apr;178(7):1620-1638
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Yang GS, Zheng B, Qin Y, Zhou J, Yang Z, Zhang XH, Zhao HY, Yang HJ, Wen JK
Theranostics 2020;10(17):7787-7811
Theranostics 2020;10(17):7787-7811
Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells.
Zhao Y, Tang J, Yang D, Tang C, Chen J
Journal of dairy science 2020 Sep;103(9):8350-8359
Journal of dairy science 2020 Sep;103(9):8350-8359
Downregulation of G3BP2 reduces atherosclerotic lesions in ApoE-/- mice.
Li T, Safitri M, Zhang K, Wang Y, Huang L, Zhu Y, Daniel R, Wu LJ, Qiu J, Wang G
Atherosclerosis 2020 Oct;310:64-74
Atherosclerosis 2020 Oct;310:64-74
Endothelial intercellular cell adhesion molecule 1 contributes to cell aggregate formation in CHO cells cultured in serum-free media.
Louie S, Heidersbach A, Blanco N, Haley B, Rose CM, Liu PS, Yim M, Tang D, Lam C, Sandoval WN, Shaw D, Snedecor B, Misaghi S
Biotechnology progress 2020 May;36(3):e2951
Biotechnology progress 2020 May;36(3):e2951
Blockade of intercellular adhesion molecule-1 prevents angiotensin II-induced hypertension and vascular dysfunction.
Lang PP, Bai J, Zhang YL, Yang XL, Xia YL, Lin QY, Li HH
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):378-386
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):378-386
Quasi-ultrafine particles promote cell metastasis via HMGB1-mediated cancer cell adhesion.
Gao R, Sang N
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113390
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113390
Injected laquinimod D-α-tocopheryl polyethylene glycol-1000 succinate polymeric micelles for the treatment of inflammatory bowel disease.
Wang L, Xue P, Tong M, Chen R, Yang W, ZhuGe D, Yuan J, Yao Q, Zhao Y, Xu H
Colloids and surfaces. B, Biointerfaces 2020 Jan 1;185:110575
Colloids and surfaces. B, Biointerfaces 2020 Jan 1;185:110575
Inhibition of calcineurin/NFATc4 signaling attenuates ventilator‑induced lung injury.
Li M, Fang XZ, Liu XT, Zheng YF, Xie YB, Ma XD, Xia Y, Shao DH
Molecular medicine reports 2020 Feb;21(2):607-614
Molecular medicine reports 2020 Feb;21(2):607-614
Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway.
Chen ZQ, Sun XH, Li XJ, Xu ZC, Yang Y, Lin ZY, Xiao HM, Zhang M, Quan SJ, Huang HQ
Acta pharmacologica Sinica 2020 Dec;41(12):1587-1596
Acta pharmacologica Sinica 2020 Dec;41(12):1587-1596
DNA damage/cGAS-triggered up-regulation of MALAT1 promotes undesirable inflammatory responses in radiotherapy of cancer.
Yuan C, Wang D, Zhang N, Wang Z, Yang F, He J, Sun R, Yang X, Hu J, Wu M
Biochemical and biophysical research communications 2020 Aug 6;528(4):746-752
Biochemical and biophysical research communications 2020 Aug 6;528(4):746-752
ECM1 Prevents Activation of Transforming Growth Factor β, Hepatic Stellate Cells, and Fibrogenesis in Mice.
Fan W, Liu T, Chen W, Hammad S, Longerich T, Hausser I, Fu Y, Li N, He Y, Liu C, Zhang Y, Lian Q, Zhao X, Yan C, Li L, Yi C, Ling Z, Ma L, Zhao X, Xu H, Wang P, Cong M, You H, Liu Z, Wang Y, Chen J, Li D, Hui L, Dooley S, Hou J, Jia J, Sun B
Gastroenterology 2019 Nov;157(5):1352-1367.e13
Gastroenterology 2019 Nov;157(5):1352-1367.e13
Low-intensity pulsed ultrasound attenuates cardiac inflammation of CVB3-induced viral myocarditis via regulation of caveolin-1 and MAPK pathways.
Zheng C, Wu SM, Lian H, Lin YZ, Zhuang R, Thapa S, Chen QZ, Chen YF, Lin JF
Journal of cellular and molecular medicine 2019 Mar;23(3):1963-1975
Journal of cellular and molecular medicine 2019 Mar;23(3):1963-1975
Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats.
Deng J, Xia Y, Zhou Q, Wang X, Xiong C, Shao X, Shao M, Zou H
Transplant immunology 2019 Jun;54:20-28
Transplant immunology 2019 Jun;54:20-28
Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy.
Liu H, Lessieur EM, Saadane A, Lindstrom SI, Taylor PR, Kern TS
Diabetologia 2019 Dec;62(12):2365-2374
Diabetologia 2019 Dec;62(12):2365-2374
TRPC6 modulates adhesion of neutrophils to airway epithelial cells via NF-κB activation and ICAM-1 expression with ozone exposure.
Chen QZ, Zhou YB, Zhou LF, Fu ZD, Wu YS, Chen Y, Li SN, Huang JR, Li JH
Experimental cell research 2019 Apr 15;377(1-2):56-66
Experimental cell research 2019 Apr 15;377(1-2):56-66
Ulcerative colitis-specific delivery of keratinocyte growth factor by neutrophils-simulated liposomes facilitates the morphologic and functional recovery of the damaged colon through alleviating the inflammation.
Zhao YZ, ZhuGe DL, Tong MQ, Lin MT, Zheng YW, Jiang X, Yang WG, Yao Q, Xiang Q, Li XK, Xu HL
Journal of controlled release : official journal of the Controlled Release Society 2019 Apr 10;299:90-106
Journal of controlled release : official journal of the Controlled Release Society 2019 Apr 10;299:90-106
Effects of Qingshen Granules on the Oxidative Stress-NF/kB Signal Pathway in Unilateral Ureteral Obstruction Rats.
Jin H, Wang Y, Wang D, Zhang L
Evidence-based complementary and alternative medicine : eCAM 2018;2018:4761925
Evidence-based complementary and alternative medicine : eCAM 2018;2018:4761925
Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival.
Lorenz L, Axnick J, Buschmann T, Henning C, Urner S, Fang S, Nurmi H, Eichhorst N, Holtmeier R, Bódis K, Hwang JH, Müssig K, Eberhard D, Stypmann J, Kuss O, Roden M, Alitalo K, Häussinger D, Lammert E
Nature 2018 Oct;562(7725):128-132
Nature 2018 Oct;562(7725):128-132
Control release of mitochondria-targeted antioxidant by injectable self-assembling peptide hydrogel ameliorated persistent mitochondrial dysfunction and inflammation after acute kidney injury.
Zhao M, Zhou Y, Liu S, Li L, Chen Y, Cheng J, Lu Y, Liu J
Drug delivery 2018 Nov;25(1):546-554
Drug delivery 2018 Nov;25(1):546-554
Expression and significance of Sirt1 in renal allografts at the early stage of chronic renal allograft dysfunction.
Xia Y, Deng J, Zhou Q, Shao X, Yang X, Sha M, Zou H
Transplant immunology 2018 Jun;48:18-25
Transplant immunology 2018 Jun;48:18-25
Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice.
Leibing T, Géraud C, Augustin I, Boutros M, Augustin HG, Okun JG, Langhans CD, Zierow J, Wohlfeil SA, Olsavszky V, Schledzewski K, Goerdt S, Koch PS
Hepatology (Baltimore, Md.) 2018 Aug;68(2):707-722
Hepatology (Baltimore, Md.) 2018 Aug;68(2):707-722
Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites.
Feng S, Bowden N, Fragiadaki M, Souilhol C, Hsiao S, Mahmoud M, Allen S, Pirri D, Ayllon BT, Akhtar S, Thompson AAR, Jo H, Weber C, Ridger V, Schober A, Evans PC
Arteriosclerosis, thrombosis, and vascular biology 2017 Nov;37(11):2087-2101
Arteriosclerosis, thrombosis, and vascular biology 2017 Nov;37(11):2087-2101
Extracts of Zuo Jin Wan, a traditional Chinese medicine, phenocopies 5-HTR1D antagonist in attenuating Wnt/β-catenin signaling in colorectal cancer cells.
Pan J, Xu Y, Song H, Zhou X, Yao Z, Ji G
BMC complementary and alternative medicine 2017 Nov 28;17(1):506
BMC complementary and alternative medicine 2017 Nov 28;17(1):506
BTP2, a Store-Operated Calcium Channel Inhibitor, Attenuates Lung Ischemia-Reperfusion Injury in Rats.
Zhang W, Qi Z, Wang Y
Inflammation 2017 Jun;40(3):778-787
Inflammation 2017 Jun;40(3):778-787
In vitro assessment of deferoxamine on mesenchymal stromal cells from tumor and bone marrow.
Wang G, Shen G, Yin T
Environmental toxicology and pharmacology 2017 Jan;49:58-64
Environmental toxicology and pharmacology 2017 Jan;49:58-64
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
Gu R, Lei B, Jiang C, Xu G
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J
Diabetes research and clinical practice 2017 Feb;124:30-40
Diabetes research and clinical practice 2017 Feb;124:30-40
Puerarin Improves Diabetic Aorta Injury by Inhibiting NADPH Oxidase-Derived Oxidative Stress in STZ-Induced Diabetic Rats.
Li W, Zhao W, Wu Q, Lu Y, Shi J, Chen X
Journal of diabetes research 2016;2016:8541520
Journal of diabetes research 2016;2016:8541520
Human β-defensin-3 alleviates the progression of atherosclerosis accelerated by Porphyromonas gingivalis lipopolysaccharide.
Li L, Bian T, Lyu J, Cui D, Lei L, Yan F
International immunopharmacology 2016 Sep;38:204-13
International immunopharmacology 2016 Sep;38:204-13
Neuroprotective effects of Kaempferide-7-O-(4″-O-acetylrhamnosyl)-3-O-rutinoside on cerebral ischemia-reperfusion injury in rats.
Wang S, Xu H, Xin Y, Li M, Fu W, Wang Y, Lu Z, Yu X, Sui D
European journal of pharmacology 2016 Oct 5;788:335-342
European journal of pharmacology 2016 Oct 5;788:335-342
FTY720 Attenuates Retinal Inflammation and Protects Blood-Retinal Barrier in Diabetic Rats.
Fan L, Yan H
Investigative ophthalmology & visual science 2016 Mar;57(3):1254-63
Investigative ophthalmology & visual science 2016 Mar;57(3):1254-63
Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes.
Liu H, Tang J, Du Y, Saadane A, Tonade D, Samuels I, Veenstra A, Palczewski K, Kern TS
Investigative ophthalmology & visual science 2016 Aug 1;57(10):4272-81
Investigative ophthalmology & visual science 2016 Aug 1;57(10):4272-81
Early treatment with atorvastatin exerts parenchymal and vascular protective effects in experimental cerebral ischaemia.
Potey C, Ouk T, Petrault O, Petrault M, Berezowski V, Salleron J, Bordet R, Gautier S
British journal of pharmacology 2015 Nov;172(21):5188-98
British journal of pharmacology 2015 Nov;172(21):5188-98
Anti-inflammation Effects of Oxysophoridine on Cerebral Ischemia-Reperfusion Injury in Mice.
Wang YS, Li YX, Zhao P, Wang HB, Zhou R, Hao YJ, Wang J, Wang SJ, Du J, Ma L, Sun T, Yu JQ
Inflammation 2015 Dec;38(6):2259-68
Inflammation 2015 Dec;38(6):2259-68
Endothelial precursor cells promote angiogenesis in hepatocellular carcinoma.
Sun XT, Yuan XW, Zhu HT, Deng ZM, Yu DC, Zhou X, Ding YT
World journal of gastroenterology 2012 Sep 21;18(35):4925-33
World journal of gastroenterology 2012 Sep 21;18(35):4925-33
Bone marrow cells: Important role on neovascularization of hepatocellular carcinoma.
Zhu H, Shao Q, Sun X, Deng Z, Yuan X, Zhou X, Ding Y
Journal of gastroenterology and hepatology 2012 Jul;27(7):1241-51
Journal of gastroenterology and hepatology 2012 Jul;27(7):1241-51
Effects of pegylated interferon α2b on metastasis of hepatocellular carcinoma.
Arakawa Y, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T
The Journal of surgical research 2012 Jan;172(1):95-101
The Journal of surgical research 2012 Jan;172(1):95-101
Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation.
Garin A, Meyer-Hermann M, Contie M, Figge MT, Buatois V, Gunzer M, Toellner KM, Elson G, Kosco-Vilbois MH
Immunity 2010 Jul 23;33(1):84-95
Immunity 2010 Jul 23;33(1):84-95
Tumor-derived intercellular adhesion molecule-1 mediates tumor-associated leukocyte infiltration in orthotopic pancreatic xenografts.
Roland CL, Dineen SP, Toombs JE, Carbon JG, Smith CW, Brekken RA, Barnett CC Jr
Experimental biology and medicine (Maywood, N.J.) 2010 Feb;235(2):263-70
Experimental biology and medicine (Maywood, N.J.) 2010 Feb;235(2):263-70
Cyclosporin A and phenytoin modulate inflammatory responses.
Suzuki AM, Yoshimura A, Ozaki Y, Kaneko T, Hara Y
Journal of dental research 2009 Dec;88(12):1131-6
Journal of dental research 2009 Dec;88(12):1131-6
Effects of sodium beta-aescin on expression of adhesion molecules and migration of neutrophils after middle cerebral artery occlusion in rats.
Hu XM, Zhang Y, Zeng FD
Acta pharmacologica Sinica 2004 Jul;25(7):869-75
Acta pharmacologica Sinica 2004 Jul;25(7):869-75
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Icam1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of mouse Icam1. This antibody recognizes mouse, rat antigen. The Icam1 antibody has been validated for the following applications: ELISA, WB analysis.
