Antibody data
- Antibody Data
- Antigen structure
- References [30]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 15833-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15833-1-AP, RRID:AB_2216309
- Product name
- Vitronectin antibody
- Antibody type
- Polyclonal
- Description
- Vitronectin antibody (Cat. #15833-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age-Related Macular Degeneration.
Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.
S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice From FOLFOX-Induced Liver Injury.
Altered pattern of proteolysis in rhegmatogenous retinal detachment by mining of N-termini datasets from vitreous humor proteome.
Temporal Proteome Profiling of Anterior Cruciate Ligament Tear Remnants: Secretory Proteins in the Acute Phase Potentially Promote Tissue Repair.
Characterization of Protein Expression and Signaling Pathway Activation That May Contribute to Differential Biological Functions in Porcine Arterial and Venous Smooth Muscle Cells.
Up-regulated vitronectin in Kawasaki disease shock syndrome serves as a potential biomarker.
Multi-omics analysis reveals the pre-protective mechanism of Dendrobium flexicaule polysaccharide against alcohol-induced gastric mucosal injury.
Uremic serum exposure leads to differential phenotypic switch in porcine arterial and venous smooth muscle cells.
Insufficient expression of VTN promotes the development of early-onset severe preeclampsia through the HEY1/autophagy signaling pathway.
Vitronectin stimulates hepatic gluconeogenesis by activating the cAMP/PKA/CREB axis in the liver.
Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury.
Follicular fluid aids cell adhesion, spreading in an age independent manner and shows an age-dependent effect on DNA damage in fallopian tube epithelial cells.
Proteomics and phosphoproteomics to study Tuina reverses capsule fibrosis in frozen shoulder: a research report based on rats.
Characterization of drusen formation in a primary porcine tissue culture model of dry AMD.
Vitronectin promotes insulin resistance in trophoblast cells by activating JNK in gestational diabetes mellitus.
Binding of serum-derived amyloid-associated proteins to amyloid fibrils.
The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome.
Isolation, culture, and cryosectioning of primary porcine retinal pigment epithelium on transwell cell culture inserts.
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.
Intervertebral disc regeneration with an adipose mesenchymal stem cell-derived tissue-engineered construct in a rat nucleotomy model.
Induction of migration of periodontal ligament cells by selective regulation of integrin subunits.
VEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer.
Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.
Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.
Characterization of Initial Cell Adhesion on Charged Polymer Substrates in Serum-Containing and Serum-Free Media.
Surface changes of nanotopography by carbon ion implantation to enhance the biocompatibility of silicone rubber: an in vitro study of the optimum ion fluence and adsorbed protein.
SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.
Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis.
Molins B, Nabaes Jodar MS, de Oliveira E, Estanyol JM, Peña E, Bezunartea J, Hernández M, Figueras-Roca M, Adan A
Aging cell 2026 May;25(5):e70501
Aging cell 2026 May;25(5):e70501
Targeting TFAM K76 acetylation attenuates mitochondrial dysfunction and kidney injury in diabetic kidney disease.
Fu T, Sun S, Wang Z, Zhao F, Zhen J, Ji X, Xue F, Mu Q, Wang Y, Liu Y, Wan Q
Cardiovascular diabetology 2026 Feb 3;25(1)
Cardiovascular diabetology 2026 Feb 3;25(1)
S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice From FOLFOX-Induced Liver Injury.
Gangi A, Li TWH, Lim Y, Chandla S, Floris A, Khangholi A, Tomasi ML, Lu SC
Cellular and molecular gastroenterology and hepatology 2025;19(8):101513
Cellular and molecular gastroenterology and hepatology 2025;19(8):101513
Altered pattern of proteolysis in rhegmatogenous retinal detachment by mining of N-termini datasets from vitreous humor proteome.
Zingale GA, Giammaria S, Pandino I, Placentino L, Ripandelli G, Tundo GR, Grasso G, Bocedi A, Bell PA, Rossi T, Sbardella D
Scientific reports 2025 Oct 14;15(1):35848
Scientific reports 2025 Oct 14;15(1):35848
Temporal Proteome Profiling of Anterior Cruciate Ligament Tear Remnants: Secretory Proteins in the Acute Phase Potentially Promote Tissue Repair.
Liu Y, Li B, Zhang J, Zhao B, Chen L, Chen B
Journal of proteome research 2025 May 2;24(5):2302-2313
Journal of proteome research 2025 May 2;24(5):2302-2313
Characterization of Protein Expression and Signaling Pathway Activation That May Contribute to Differential Biological Functions in Porcine Arterial and Venous Smooth Muscle Cells.
Arteaga EC, Wai C, Uriyanghai U, Rudraraju M, Su H, Sudarsanam VA, Haddad SO, Poulton JS, Roy-Chaudhury P, Xi G
International journal of molecular sciences 2025 Mar 28;26(7)
International journal of molecular sciences 2025 Mar 28;26(7)
Up-regulated vitronectin in Kawasaki disease shock syndrome serves as a potential biomarker.
Wei Z, Bai B, Zheng Y, Wang H, Zhang M, Zhang Q, Li X
Translational pediatrics 2025 Jun 27;14(6):1230-1244
Translational pediatrics 2025 Jun 27;14(6):1230-1244
Multi-omics analysis reveals the pre-protective mechanism of Dendrobium flexicaule polysaccharide against alcohol-induced gastric mucosal injury.
Wang F, Yuan C, Deng R, Liu Y
International journal of biological macromolecules 2025 Feb;291:139191
International journal of biological macromolecules 2025 Feb;291:139191
Uremic serum exposure leads to differential phenotypic switch in porcine arterial and venous smooth muscle cells.
Su H, Uriyanghai U, Wai C, Arteaga EC, Wan H, Adam KP, Sudarsanam VA, Haddad SO, Yang A, Li L, Bahnson EM, Poulton JS, Roy-Chaudhury P, Xi G
American journal of physiology. Renal physiology 2025 Dec 1;329(6):F809-F819
American journal of physiology. Renal physiology 2025 Dec 1;329(6):F809-F819
Insufficient expression of VTN promotes the development of early-onset severe preeclampsia through the HEY1/autophagy signaling pathway.
Qi G, Gong Y, Li Y, Jin Y, Chi S, Zhang W, Luo X
Placenta 2025 Aug;168:56-66
Placenta 2025 Aug;168:56-66
Vitronectin stimulates hepatic gluconeogenesis by activating the cAMP/PKA/CREB axis in the liver.
Ju Y, Wu R, Wang G, Shen T, Hu J, Kong Y
Molecular and cellular endocrinology 2025 Apr 1;599:112485
Molecular and cellular endocrinology 2025 Apr 1;599:112485
Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury.
Wang S, Wang X, Shan Y, Tan Z, Su Y, Cao Y, Wang S, Dong J, Gu J, Wang Y
Cell stem cell 2024 Mar 7;31(3):341-358.e7
Cell stem cell 2024 Mar 7;31(3):341-358.e7
Follicular fluid aids cell adhesion, spreading in an age independent manner and shows an age-dependent effect on DNA damage in fallopian tube epithelial cells.
Salvi A, Li W, Dipali SS, Cologna SM, Pavone ME, Duncan FE, Burdette JE
Heliyon 2024 Mar 30;10(6):e27336
Heliyon 2024 Mar 30;10(6):e27336
Proteomics and phosphoproteomics to study Tuina reverses capsule fibrosis in frozen shoulder: a research report based on rats.
Qiao Y, Wang J, Zheng L, Yang Y, Li H, Li M, Zhang S, Wang H, Zhang T
Scientific reports 2024 Jan 5;14(1):661
Scientific reports 2024 Jan 5;14(1):661
Characterization of drusen formation in a primary porcine tissue culture model of dry AMD.
Shaw EM, Tate AJ, Periasamy R, Lipinski DM
Molecular therapy. Methods & clinical development 2024 Dec 12;32(4):101331
Molecular therapy. Methods & clinical development 2024 Dec 12;32(4):101331
Vitronectin promotes insulin resistance in trophoblast cells by activating JNK in gestational diabetes mellitus.
Ju Y, Shen T, Guo Z, Kong Y, Huang Y, Hu J
Cell biology international 2024 Apr 23;
Cell biology international 2024 Apr 23;
Binding of serum-derived amyloid-associated proteins to amyloid fibrils.
Misumi Y, Tabata Y, Tasaki M, Obayashi K, Yamakawa S, Nomura T, Ueda M
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2023 Mar;30(1):67-73
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2023 Mar;30(1):67-73
The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome.
Zhao B, Wu C, Sammad A, Ma Z, Suo L, Wu Y, Fu X
BMC genomics 2022 Mar 7;23(1):191
BMC genomics 2022 Mar 7;23(1):191
Isolation, culture, and cryosectioning of primary porcine retinal pigment epithelium on transwell cell culture inserts.
Hood EMS, Curcio CA, Lipinski D
STAR protocols 2022 Dec 16;3(4):101758
STAR protocols 2022 Dec 16;3(4):101758
Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.
Tougan T, Edula JR, Morita M, Takashima E, Honma H, Tsuboi T, Horii T
Malaria journal 2020 Apr 15;19(1):155
Malaria journal 2020 Apr 15;19(1):155
Intervertebral disc regeneration with an adipose mesenchymal stem cell-derived tissue-engineered construct in a rat nucleotomy model.
Ishiguro H, Kaito T, Yarimitsu S, Hashimoto K, Okada R, Kushioka J, Chijimatsu R, Takenaka S, Makino T, Sakai Y, Moriguchi Y, Otsuru S, Hart DA, Fujie H, Nakamura N, Yoshikawa H
Acta biomaterialia 2019 Mar 15;87:118-129
Acta biomaterialia 2019 Mar 15;87:118-129
Induction of migration of periodontal ligament cells by selective regulation of integrin subunits.
Kawamura M, Yamamoto T, Yamashiro K, Kochi S, Yoshihara-Hirata C, Ideguchi H, Aoyagi H, Omori K, Takashiba S
Journal of cellular and molecular medicine 2019 Feb;23(2):1211-1223
Journal of cellular and molecular medicine 2019 Feb;23(2):1211-1223
VEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer.
Lian L, Li XL, Xu MD, Li XM, Wu MY, Zhang Y, Tao M, Li W, Shen XM, Zhou C, Jiang M
BMC cancer 2019 Feb 28;19(1):183
BMC cancer 2019 Feb 28;19(1):183
Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.
Wang H, Ning T, Song C, Luo X, Xu S, Zhang X, Deng Z, Ma D, Wu B
Journal of cellular physiology 2019 Aug;234(8):12897-12909
Journal of cellular physiology 2019 Aug;234(8):12897-12909
Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.
Tougan T, Edula JR, Takashima E, Morita M, Shinohara M, Shinohara A, Tsuboi T, Horii T
Scientific reports 2018 Mar 22;8(1):5052
Scientific reports 2018 Mar 22;8(1):5052
Characterization of Initial Cell Adhesion on Charged Polymer Substrates in Serum-Containing and Serum-Free Media.
Hoshiba T, Yoshikawa C, Sakakibara K
Langmuir : the ACS journal of surfaces and colloids 2018 Apr 3;34(13):4043-4051
Langmuir : the ACS journal of surfaces and colloids 2018 Apr 3;34(13):4043-4051
Surface changes of nanotopography by carbon ion implantation to enhance the biocompatibility of silicone rubber: an in vitro study of the optimum ion fluence and adsorbed protein.
Li X, Zhou X, Chen Y, Yu S, Chen X, Xia X, Shi X, Zhang Y, Fan D
Journal of materials science. Materials in medicine 2017 Sep 15;28(10):167
Journal of materials science. Materials in medicine 2017 Sep 15;28(10):167
SILAC-based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells.
Zhang H, Wu P, Chen F, Hao Y, Lao Y, Ren L, Sun L, Sun W, Wei H, Chan DW, Jiang Y, He F
Proteomics 2014 Sep;14(17-18):1977-86
Proteomics 2014 Sep;14(17-18):1977-86
Secretomes are a potential source of molecular targets for cancer therapies and indicate that APOE is a candidate biomarker for lung adenocarcinoma metastasis.
Liu Z, Gao Y, Hao F, Lou X, Zhang X, Li Y, Wu D, Xiao T, Yang L, Li Q, Qiu X, Wang E
Molecular biology reports 2014 Nov;41(11):7507-23
Molecular biology reports 2014 Nov;41(11):7507-23
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human serum tissue were subjected to SDS PAGE followed by western blot with 15833-1-AP(VTN antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The Vitronectin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Vitronectin. This antibody recognizes human,mouse,rat antigen. The Vitronectin antibody has been validated for the following applications: ELISA, WB, IHC analysis.