BMS109

antibody from Invitrogen Antibodies
Targeting: ICAM2 CD102
Provider product page for BMS109
ELISA
Immunohistochemistry
Flow cytometry
Other assay

Antibody data

Product number
BMS109 - Provider product page
Provider
Invitrogen Antibodies
Product name
CD102 (ICAM-2) Monoclonal Antibody (CBR-IC2/2), eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: BMS109 does not cross react with mouse. Intercellular Adhesion Molecule-2 (ICAM-2) is a 60 kDa surface glycoprotein that promotes adhesion between immune cells and the vascular endothelium. ICAM-2 is a member of the Ig-superfamily with two immunoglobulin-like extracellular domains. ICAM-2 is much more closely related to the two N-terminal domains of ICAM-1 (34% identity) than either ICAM-1 or ICAM-2 is to other members of the Ig-superfamily, demonstrating the existence of a subfamily of Ig-like ligands that bind the same integrin receptor. ICAM-2 is broadly distributed on hematopoietic cells. On resting lymphocytes, the ICAM-2 expression is several-fold higher than that seen with ICAM-1, while monocytes express equivalent levels of ICAM-1 and ICAM-2. In contrast to ICAM-1, neutrophils stain negative for ICAM-2. Just little or no ICAM-2 staining can be demonstrated on other cell lines, the sole exception being resting vascular endothelial cells, which possess high levels of ICAM-2, and small clusters of cells in lymphoid tissue germinal centres. ICAM-2 expression is unaffected by a variety of inflammatory cytokines. Applications Tested: ELISA, Flow Cytometry, Functional Studies (Blocking), Immunohistochemistry. Purity: >95%.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
CBR-IC2/2
Vial size
50 µg
Concentration
0.5 mg/mL
Storage
4° C
ICAM2 protein structure - BMS109 shown in red.