Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- ABIN152096 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse, Bovine, Canine
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 4B10
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS.
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors.
sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism.
microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1.
Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins.
A novel nucleocytoplasmic shuttling sequence of DAZAP1, a testis-abundant RNA-binding protein.
Heterogeneous nuclear ribonucleoprotein A1 is a novel internal ribosome entry site trans-acting factor that modulates alternative initiation of translation of the fibroblast growth factor 2 mRNA.
Altered patterns of expression of members of the heterogeneous nuclear ribonucleoprotein (hnRNP) family in lung cancer.
Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation.
Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: candidate intermediates in formation and export of mRNA.
Transcription-dependent nucleocytoplasmic distribution of hnRNP A1 protein in early mouse embryos.
The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation.
hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer.
Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.
A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export.
Transcription-dependent and transcription-independent nuclear transport of hnRNP proteins.
A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts.
Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins.
Kamelgarn M, Chen J, Kuang L, Arenas A, Zhai J, Zhu H, Gal J
Biochimica et biophysica acta 2016 Oct;1862(10):2004-14
Biochimica et biophysica acta 2016 Oct;1862(10):2004-14
AKAP95 regulates splicing through scaffolding RNAs and RNA processing factors.
Hu J, Khodadadi-Jamayran A, Mao M, Shah K, Yang Z, Nasim MT, Wang Z, Jiang H
Nature communications 2016 Nov 8;7:13347
Nature communications 2016 Nov 8;7:13347
sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism.
Kunze MM, Benz F, Brauß TF, Lampe S, Weigand JE, Braun J, Richter FM, Wittig I, Brüne B, Schmid T
Biochimica et biophysica acta 2016 Jul;1859(7):848-59
Biochimica et biophysica acta 2016 Jul;1859(7):848-59
microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1.
Fujiya M, Konishi H, Mohamed Kamel MK, Ueno N, Inaba Y, Moriichi K, Tanabe H, Ikuta K, Ohtake T, Kohgo Y
Oncogene 2014 Oct 2;33(40):4847-56
Oncogene 2014 Oct 2;33(40):4847-56
Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins.
Huelga SC, Vu AQ, Arnold JD, Liang TY, Liu PP, Yan BY, Donohue JP, Shiue L, Hoon S, Brenner S, Ares M Jr, Yeo GW
Cell reports 2012 Feb 23;1(2):167-78
Cell reports 2012 Feb 23;1(2):167-78
A novel nucleocytoplasmic shuttling sequence of DAZAP1, a testis-abundant RNA-binding protein.
Lin YT, Yen PH
RNA (New York, N.Y.) 2006 Aug;12(8):1486-93
RNA (New York, N.Y.) 2006 Aug;12(8):1486-93
Heterogeneous nuclear ribonucleoprotein A1 is a novel internal ribosome entry site trans-acting factor that modulates alternative initiation of translation of the fibroblast growth factor 2 mRNA.
Bonnal S, Pileur F, Orsini C, Parker F, Pujol F, Prats AC, Vagner S
The Journal of biological chemistry 2005 Feb 11;280(6):4144-53
The Journal of biological chemistry 2005 Feb 11;280(6):4144-53
Altered patterns of expression of members of the heterogeneous nuclear ribonucleoprotein (hnRNP) family in lung cancer.
Pino I, Pío R, Toledo G, Zabalegui N, Vicent S, Rey N, Lozano MD, Torre W, García-Foncillas J, Montuenga LM
Lung cancer (Amsterdam, Netherlands) 2003 Aug;41(2):131-43
Lung cancer (Amsterdam, Netherlands) 2003 Aug;41(2):131-43
Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation.
Guil S, Gattoni R, Carrascal M, Abián J, Stévenin J, Bach-Elias M
Molecular and cellular biology 2003 Apr;23(8):2927-41
Molecular and cellular biology 2003 Apr;23(8):2927-41
Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: candidate intermediates in formation and export of mRNA.
Mili S, Shu HJ, Zhao Y, Piñol-Roma S
Molecular and cellular biology 2001 Nov;21(21):7307-19
Molecular and cellular biology 2001 Nov;21(21):7307-19
Transcription-dependent nucleocytoplasmic distribution of hnRNP A1 protein in early mouse embryos.
Vautier D, Chesné P, Cunha C, Calado A, Renard JP, Carmo-Fonseca M
Journal of cell science 2001 Apr;114(Pt 8):1521-31
Journal of cell science 2001 Apr;114(Pt 8):1521-31
The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation.
van der Houven van Oordt W, Diaz-Meco MT, Lozano J, Krainer AR, Moscat J, Cáceres JF
The Journal of cell biology 2000 Apr 17;149(2):307-16
The Journal of cell biology 2000 Apr 17;149(2):307-16
hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer.
Del Gatto-Konczak F, Olive M, Gesnel MC, Breathnach R
Molecular and cellular biology 1999 Jan;19(1):251-60
Molecular and cellular biology 1999 Jan;19(1):251-60
Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.
Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G
The Journal of cell biology 1997 Sep 22;138(6):1181-92
The Journal of cell biology 1997 Sep 22;138(6):1181-92
A role for the M9 transport signal of hnRNP A1 in mRNA nuclear export.
Izaurralde E, Jarmolowski A, Beisel C, Mattaj IW, Dreyfuss G, Fischer U
The Journal of cell biology 1997 Apr 7;137(1):27-35
The Journal of cell biology 1997 Apr 7;137(1):27-35
Transcription-dependent and transcription-independent nuclear transport of hnRNP proteins.
Piñol-Roma S, Dreyfuss G
Science (New York, N.Y.) 1991 Jul 19;253(5017):312-4
Science (New York, N.Y.) 1991 Jul 19;253(5017):312-4
A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts.
Piñol-Roma S, Swanson MS, Gall JG, Dreyfuss G
The Journal of cell biology 1989 Dec;109(6 Pt 1):2575-87
The Journal of cell biology 1989 Dec;109(6 Pt 1):2575-87
Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins.
Piñol-Roma S, Choi YD, Matunis MJ, Dreyfuss G
Genes & development 1988 Feb;2(2):215-27
Genes & development 1988 Feb;2(2):215-27
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB