orb385815

antibody from Biorbyt

Targeting: CSF3 C17orf33, G-CSF, GCSF, MGC45931

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

orb385815

Provider

Biorbyt

Product name

CSF3 Antibody / Granulocyte-Colony Stimulating Factor

Antibody type

Monoclonal

Description

This mAb recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSF's, which are identical except for a three amino acid deletion in the amino-terminus of one form of the protein have been isolated from human cells. Murine and human G-CSF's share 73% sequence identity at the amino acid level.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antibody clone number

PRPN2-1

Vial size

20 ug

Storage

Store the G-CSF antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).