12-7351-41

antibody from Invitrogen Antibodies
Targeting: CSF3 C17orf33, G-CSF, GCSF, MGC45931
Provider product page for 12-7351-41

Antibody data

Product number
12-7351-41 - Provider product page
Provider
Invitrogen Antibodies
Product name
G-CSF Monoclonal Antibody (8F5CSF), PE, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: G-CSF (Granulocyte colony-stimulating factor) is a growth factor that stimulates the proliferation, differentiation, and mobilization of hematopoetic stem cells. It is expressed by monocytes, macrophages, and bone marrow stromal cells, and can also be induced in fibroblasts by IL-17A. Unlike GM-CSF and IL-3, which can stimulate cells of multiple lineages, G-CSF activity is limited to neutrophilic granulocytes. G-CSF is essential to the maintenance of neutrophil counts during homeostasis, and low basal levels of the protein are detectable in the serum of healthy individuals. Circulating levels become elevated rapidly upon infection, as G-CSF is also important for the activation and mobilization of mature neutrophils during the innate immune response. G-CSF therapy is commonly used to treat neutropenia following bone marrow transplant or chemotherapy. Applications Reported: This 8F5CSF antibody has been reported for use in intracellular staining and flow cytometric analysis. Applications Tested: This 8F5CSF antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Isotype
IgG
Antibody clone number
8F5CSF
Vial size
25 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
CSF3 protein structure - 12-7351-41 shown in red.