Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS6287 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PSMA3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human PSMA3.
- Description
- The 20S proteasome is the major proteolytic enzyme complex involved in intracellular protein degradation. It consists of four stacked rings, each with seven distinct subunits. The two outer layers are identical rings composed of Ï« subunits (called PSMAs), and the two inner layers are identical rings composed of ÉÇ subunits. While the catalytic sites are located on the ÉÇ rings, the Ï« subunits are important for assembly and as binding sites for regulatory proteins. Seven different Ï« and ten different ÉÇ proteasome genes have been identified in mammals. PA700, PA28, and PA200 are three major protein complexes that function as activators of the 20S proteasome. PA700 binds polyubiquitin with high affinity and associates with the 20S proteasome to form the 26S proteasome, which preferentially degrades poly-ubiquitinated proteins ).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- WesternBlot (WB) analysis of PSMA3 pAb in extracts from JAR, A549 and PC12 cells.