BS6287

antibody from Bioworld Technology, Inc
Targeting: PSMA3 HC8
Provider product page for BS6287
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6287 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PSMA3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PSMA3.
Description
The 20S proteasome is the major proteolytic enzyme complex involved in intracellular protein degradation. It consists of four stacked rings, each with seven distinct subunits. The two outer layers are identical rings composed of Ï« subunits (called PSMAs), and the two inner layers are identical rings composed of ÉÇ subunits. While the catalytic sites are located on the ÉÇ rings, the Ï« subunits are important for assembly and as binding sites for regulatory proteins. Seven different Ï« and ten different ÉÇ proteasome genes have been identified in mammals. PA700, PA28, and PA200 are three major protein complexes that function as activators of the 20S proteasome. PA700 binds polyubiquitin with high affinity and associates with the 20S proteasome to form the 26S proteasome, which preferentially degrades poly-ubiquitinated proteins ).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PSMA3 protein structure - BS6287 shown in red.