Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MA5-14857 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Phospho-IKK alpha/beta (Ser176, Ser177) Monoclonal Antibody (J.10.3)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- It is not recommended to aliquot this antibody.
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Rabbit
- Isotype
- IgG
- Antibody clone number
- J.10.3
- Vial size
- 100 µL
- Concentration
- 88 µg/mL
- Storage
- -20°C
Submitted references Targeting Macrophage Histone H3 Modification as a Leishmania Strategy to Dampen the NF-κB/NLRP3-Mediated Inflammatory Response.
Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence.
Lecoeur H, Prina E, Rosazza T, Kokou K, N'Diaye P, Aulner N, Varet H, Bussotti G, Xing Y, Milon G, Weil R, Meng G, Späth GF
Cell reports 2020 Feb 11;30(6):1870-1882.e4
Cell reports 2020 Feb 11;30(6):1870-1882.e4
Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence.
Liu Y, Hawkins OE, Su Y, Vilgelm AE, Sobolik T, Thu YM, Kantrow S, Splittgerber RC, Short S, Amiri KI, Ecsedy JA, Sosman JA, Kelley MC, Richmond A
EMBO molecular medicine 2013 Jan;5(1):149-66
EMBO molecular medicine 2013 Jan;5(1):149-66
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of Phospho-IKK-alpha pSer176 /IKKbeta pSer177 in extracts from differentiated THP-1 cells, untreated or LPS-treated for 15 minutes, using Phospho-IKK-alpha pSer176 /IKKbeta pSer177 monoclonal antibody (Product # MA5-14857) (upper), IKK-alpha antibody (middle) and IKK-beta monoclonal antibody (lower).