M121

antibody from Invitrogen Antibodies

Targeting: IL23A IL-23, IL-23A, IL23P19, P19, SGRF

No application information provided.

Antibody Data

Product number

M121

Provider

Invitrogen Antibodies

Product name

IL-12/IL-23 p40 Monoclonal Antibody (C8.6)

Antibody type

Monoclonal

Antigen

Recombinant full-length protein

Description

This antibody is specific for natural IL-12 and recognizes the p70 heterodimer as well as the p40 subunit (monomers and homodimers). It will not cross-react with the p35 subunit.

Antibody clone number

C8.6

Concentration

1 mg/mL

References

Submitted references

Hepatitis C virus modulates human monocyte-derived dendritic cells.

Eksioglu EA, Bess JR, Zhu H, Xu Y, Dong HJ, Elyar J, Nelson DR, Liu C
Journal of viral hepatitis 2010 Nov;17(11):757-69

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Lyme arthritis synovial gammadelta T cells instruct dendritic cells via fas ligand.

Collins C, Wolfe J, Roessner K, Shi C, Sigal LH, Budd RC
Journal of immunology (Baltimore, Md. : 1950) 2005 Nov 1;175(9):5656-65

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Monocyte chemoattractant protein-1 levels in bronchoalveolar lavage fluid of lung-transplanted patients treated with tacrolimus as rescue treatment for refractory acute rejection.

Meloni F, Cascina A, Paschetto E, Marone Bianco A, Morosini M, Pellegrini C, Fietta A, Vitulo P, Pozzi E, Viganò M
Transplantation proceedings 2003 Jun;35(4):1523-6

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Monocyte induction of IL-10 and down-regulation of IL-12 by iC3b deposited in ultraviolet-exposed human skin.

Yoshida Y, Kang K, Berger M, Chen G, Gilliam AC, Moser A, Wu L, Hammerberg C, Cooper KD
Journal of immunology (Baltimore, Md. : 1950) 1998 Dec 1;161(11):5873-9

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Stimulation of human T lymphocytes by LPS is MHC unrestricted, but strongly dependent on B7 interactions.

Mattern T, Flad HD, Brade L, Rietschel ET, Ulmer AJ
Journal of immunology (Baltimore, Md. : 1950) 1998 Apr 1;160(7):3412-8

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IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells.

Kaliński P, Hilkens CM, Snijders A, Snijdewint FG, Kapsenberg ML
Journal of immunology (Baltimore, Md. : 1950) 1997 Jul 1;159(1):28-35

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Reduced IL-12 production by monocytes upon ultraviolet-B irradiation selectively limits activation of T helper-1 cells.

Kremer IB, Hilkens CM, Sylva-Steenland RM, Koomen CW, Kapsenberg ML, Bos JD, Teunissen MB
Journal of immunology (Baltimore, Md. : 1950) 1996 Sep 1;157(5):1913-8

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Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit.

Snijders A, Hilkens CM, van der Pouw Kraan TC, Engel M, Aarden LA, Kapsenberg ML
Journal of immunology (Baltimore, Md. : 1950) 1996 Feb 1;156(3):1207-12

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Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

Manetti R, Parronchi P, Giudizi MG, Piccinni MP, Maggi E, Trinchieri G, Romagnani S
The Journal of experimental medicine 1993 Apr 1;177(4):1199-204