DPABH-12285

antibody from Creative Diagnostics

Targeting: VPS4A FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1

No application information provided.

Antibody Data

Product number

DPABH-12285

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-12285, RRID:AB_2524503

Product name

Rabbit Anti-Human VPS4A Polyclonal antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16