Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS6066 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Catenin ÎÛ polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human JUP.
- Description
- The catenins, Ï«, ÉÇ and ÎÛ, are proteins which bind to the highly conserved,intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherincomplexes play an important role mediating cellular adhesion. Ï«-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. ÉÇ-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. ÉÇ-catenin has also been found in complexes with the tumor suppressor protein APC. ÎÛ-catenin, also known as plakoglobin, binds with Ï«-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTPÃ× associates with catenin/cadherin complexes and may regulate complex signaling.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- WesternBlot (WB) analysis of Catenin-¦Ã pAb in extracts from MCF7, 293T, HT29, SW480 cells and mouse lung tissue.