orb385949

antibody from Biorbyt
Targeting: JUP CTNNG, DP3, DPIII, PDGB, PKGB
Provider product page for orb385949
Western blot
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb385949 - Provider product page
Provider
Biorbyt
Product name
Gamma Catenin Antibody / Plakoglobin
Antibody type
Monoclonal
Description
Plakoglobin, or gamma Catenin, is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of Plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). [UniProt]
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
15F11
Vial size
20 ug
Storage
Store the Plakoglobin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
JUP protein structure - orb385949 shown in red.