FNab01483

antibody from FineTest Biotech
Targeting: CD44 CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1
Provider product page for FNab01483
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
FNab01483 - Provider product page
Provider
FineTest Biotech
Product name
CD44 antibody
Antibody type
Monoclonal
Antigen
Recombinant protein fragment
Description
Receptor for hyaluronic acid(HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases(MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T(iTreg) cell stability and suppressive function(By similarity).
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
CD44 molecule(Indian blood group)
Epitope
IgG2a
Isotype
IgG
Antibody clone number
7D6
Vial size
100¦Ìg
Concentration
Protein A+G purification
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
CD44 protein structure - FNab01483 shown in red.