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LearnFAB3660P
antibody from R&D Systems
Targeting: CD44
CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB3660P - Provider product page
- Provider
- R&D Systems
- Product name
- Human CD44 v6 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human CD44 v6 in Western blots. By flow cytometry analysis using a panel of CD44-transfected COS cells (9), monoclonal antibody clone 2F10 was deduced to be specific for human CD44 protein isoforms containing variant exon 6 (CD44 v6).
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 2F10
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance.
Coexpression of EpCAM, CD44 variant isoforms and claudin-7 in anaplastic thyroid carcinoma.
Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer.
Preferential migration of T regulatory cells induced by IL-16.
Preferential migration of T regulatory cells induced by IL-16.
Whelan KA, Chandramouleeswaran PM, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, Darling DS, Kita Y, Natsugoe S, Winkler JD, Klein-Szanto AJ, Amaravadi RK, Avadhani NG, Rustgi AK, Nakagawa H
Oncogene 2017 Aug 24;36(34):4843-4858
Oncogene 2017 Aug 24;36(34):4843-4858
Coexpression of EpCAM, CD44 variant isoforms and claudin-7 in anaplastic thyroid carcinoma.
Okada T, Nakamura T, Watanabe T, Onoda N, Ashida A, Okuyama R, Ito K
PloS one 2014;9(4):e94487
PloS one 2014;9(4):e94487
Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer.
Krishnamachary B, Penet MF, Nimmagadda S, Mironchik Y, Raman V, Solaiyappan M, Semenza GL, Pomper MG, Bhujwalla ZM
PloS one 2012;7(8):e44078
PloS one 2012;7(8):e44078
Preferential migration of T regulatory cells induced by IL-16.
McFadden C, Morgan R, Rahangdale S, Green D, Yamasaki H, Center D, Cruikshank W
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 15;179(10):6439-45
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 15;179(10):6439-45
Preferential migration of T regulatory cells induced by IL-16.
McFadden C, Morgan R, Rahangdale S, Green D, Yamasaki H, Center D, Cruikshank W
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 15;179(10):6439-45
Journal of immunology (Baltimore, Md. : 1950) 2007 Nov 15;179(10):6439-45
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Supportive validation
- Submitted by
- R&D Systems (provider)
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- Experimental details
- Detection of CD44 v6 in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human CD44 v6 PE-conjugated Monoclonal Antibody (Catalog # FAB3660P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.
