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LearnHPA005785
antibody from Atlas Antibodies
Targeting: CD44
CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [25]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- HPA005785 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA005785, RRID:AB_1078467
- Product name
- Anti-CD44
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human CD44, Gene description: CD44 molecule (Indian blood group), Alternative Gene Names: CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1, Validated applications: ICC, IHC, WB, Uniprot ID: P16070, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references TempEasy 3D Hydrogel Coculture System Provides Mechanistic Insights into Prostate Cancer Bone Metastasis
Endogenous osteoprotegerin (OPG) represses ERα and promotes stemness and chemoresistance in breast cancer cells
MiR-21-5p regulates the dynamic of mitochondria network and rejuvenates the senile phenotype of bone marrow stromal cells (BMSCs) isolated from osteoporotic SAM/P6 mice
Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system
Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system
Bone marrow stromal cells (BMSCs CD45‐/CD44+/CD73+/CD90+) isolated from osteoporotic mice SAM/P6 as a novel model for osteoporosis investigation
CUL4B contributes to cancer stemness by repressing tumor suppressor miR34a in colorectal cancer
Cell–cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion
Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori–Infected CAPZA1-Overexpressing Cells
Protein and glycomic plasma markers for early detection of adenoma and colon cancer
Experimental Model of Human Malignant Mesothelioma in Athymic Mice
Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues
Toward early detection of Helicobacter pylori-associated gastric cancer
Role of MIF/CD74 signaling pathway in the development of pleural mesothelioma
The Role of CD44 and ERM Proteins in Expression and Functionality of P-glycoprotein in Breast Cancer Cells
Loss of KCNQ1 expression in stage II and stage III colon cancer is a strong prognostic factor for disease recurrence.
Murine model: maternal administration of stem cells for prevention of prematurity
EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer
A spatiotemporal observation of EndMT and mesenchymal cell colonization at the onset of human cardiac valve development
Superficial scrapings from breast tumors is a source for biobanking and research purposes
Optimization of tumor xenograft dissociation for the profiling of cell surface markers and nutrient transporters
Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay
Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status.
Synthesis of hyaluronan in oesophageal cancer cells is uncoupled from the prostaglandin–cAMP pathway
Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma
Zhang Z, Chen W, Sun M, Aalders T, Verhaegh G, Kouwer P
ACS Applied Materials & Interfaces 2024;16(20):25773-25787
ACS Applied Materials & Interfaces 2024;16(20):25773-25787
Endogenous osteoprotegerin (OPG) represses ERα and promotes stemness and chemoresistance in breast cancer cells
Alraouji N, Colak D, Al-mohanna F, Alaiya A, Aboussekhra A
Cell Death Discovery 2024;10(1)
Cell Death Discovery 2024;10(1)
MiR-21-5p regulates the dynamic of mitochondria network and rejuvenates the senile phenotype of bone marrow stromal cells (BMSCs) isolated from osteoporotic SAM/P6 mice
Sikora M, Śmieszek A, Pielok A, Marycz K
Stem Cell Research & Therapy 2023;14(1)
Stem Cell Research & Therapy 2023;14(1)
Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system
Schuth S, Le Blanc S, Krieger T, Jabs J, Schenk M, Giese N, Büchler M, Eils R, Conrad C, Strobel O
Journal of Experimental & Clinical Cancer Research 2022;41(1)
Journal of Experimental & Clinical Cancer Research 2022;41(1)
Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system
Weigert A, Zheng X, Nenzel A, Turkowski K, Günther S, Strack E, Sirait-Fischer E, Elwakeel E, Kur I, Nikam V, Valasarajan C, Winter H, Wissgott A, Voswinkel R, Grimminger F, Brüne B, Seeger W, Pullamsetti S, Savai R
Nature Communications 2022;13(1)
Nature Communications 2022;13(1)
Bone marrow stromal cells (BMSCs CD45‐/CD44+/CD73+/CD90+) isolated from osteoporotic mice SAM/P6 as a novel model for osteoporosis investigation
Sikora M, Śmieszek A, Marycz K
Journal of Cellular and Molecular Medicine 2021;25(14):6634-6651
Journal of Cellular and Molecular Medicine 2021;25(14):6634-6651
CUL4B contributes to cancer stemness by repressing tumor suppressor miR34a in colorectal cancer
Li Y, Hu H, Wang Y, Fan Y, Yang Y, Guo B, Xie X, Lian J, Jiang B, Han B, Wang Y, Shao C, Gong Y
Oncogenesis 2020;9(2)
Oncogenesis 2020;9(2)
Cell–cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion
Ilina O, Gritsenko P, Syga S, Lippoldt J, La Porta C, Chepizhko O, Grosser S, Vullings M, Bakker G, Starruß J, Bult P, Zapperi S, Käs J, Deutsch A, Friedl P
Nature Cell Biology 2020;22(9):1103-1115
Nature Cell Biology 2020;22(9):1103-1115
Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori–Infected CAPZA1-Overexpressing Cells
Tsugawa H, Kato C, Mori H, Matsuzaki J, Kameyama K, Saya H, Hatakeyama M, Suematsu M, Suzuki H
Cellular and Molecular Gastroenterology and Hepatology 2019;8(3):319-334
Cellular and Molecular Gastroenterology and Hepatology 2019;8(3):319-334
Protein and glycomic plasma markers for early detection of adenoma and colon cancer
Rho J, Ladd J, Li C, Potter J, Zhang Y, Shelley D, Shibata D, Coppola D, Yamada H, Toyoda H, Tada T, Kumada T, Brenner D, Hanash S, Lampe P
Gut 2018;67(3):473-484
Gut 2018;67(3):473-484
Experimental Model of Human Malignant Mesothelioma in Athymic Mice
Colin D, Cottet-Dumoulin D, Faivre A, Germain S, Triponez F, Serre-Beinier V
International Journal of Molecular Sciences 2018;19(7):1881
International Journal of Molecular Sciences 2018;19(7):1881
Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues
Zhou D, Alver B, Li S, Hlady R, Thompson J, Schroeder M, Lee J, Qiu J, Schwartz P, Sarkaria J, Robertson K
Genome Biology 2018;19(1)
Genome Biology 2018;19(1)
Toward early detection of Helicobacter pylori-associated gastric cancer
Walker R, Poleszczuk J, Mejia J, Lee J, Pimiento J, Malafa M, Giuliano A, Enderling H, Coppola D
Gastric Cancer 2017;21(2):196-203
Gastric Cancer 2017;21(2):196-203
Role of MIF/CD74 signaling pathway in the development of pleural mesothelioma
D’Amato-Brito C, Cipriano D, Colin D, Germain S, Seimbille Y, Robert J, Triponez F, Serre-Beinier V
Oncotarget 2016;7(10):11512-11525
Oncotarget 2016;7(10):11512-11525
The Role of CD44 and ERM Proteins in Expression and Functionality of P-glycoprotein in Breast Cancer Cells
Pokharel D, Padula M, Lu J, Jaiswal R, Djordjevic S, Bebawy M
Molecules 2016;21(3):290
Molecules 2016;21(3):290
Loss of KCNQ1 expression in stage II and stage III colon cancer is a strong prognostic factor for disease recurrence.
den Uil SH, Coupé VM, Linnekamp JF, van den Broek E, Goos JA, Delis-van Diemen PM, Belt EJ, van Grieken NC, Scott PM, Vermeulen L, Medema JP, Bril H, Stockmann HB, Cormier RT, Meijer GA, Fijneman RJ
British journal of cancer 2016 Dec 6;115(12):1565-1574
British journal of cancer 2016 Dec 6;115(12):1565-1574
Murine model: maternal administration of stem cells for prevention of prematurity
Lei J, Firdaus W, Rosenzweig J, Alrebh S, Bakhshwin A, Borbiev T, Fatemi A, Blakemore K, Johnston M, Burd I
American Journal of Obstetrics and Gynecology 2015;212(5):639.e1-639.e10
American Journal of Obstetrics and Gynecology 2015;212(5):639.e1-639.e10
EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer
Dittmar T, Schneck H, Gierke B, Uppenkamp F, Behrens B, Niederacher D, Stoecklein N, Templin M, Pawlak M, Fehm T, Neubauer H
PLOS ONE 2015;10(12):e0144535
PLOS ONE 2015;10(12):e0144535
A spatiotemporal observation of EndMT and mesenchymal cell colonization at the onset of human cardiac valve development
Monaghan M, Linneweh M, Liebscher S, Van Handel B, Layland S, Schenke-Layland K
Development 2015
Development 2015
Superficial scrapings from breast tumors is a source for biobanking and research purposes
Ma R, Fredriksson I, Karthik G, Winn G, Darai-Ramqvist E, Bergh J, Hartman J
Laboratory Investigation 2014;94(7):796-805
Laboratory Investigation 2014;94(7):796-805
Optimization of tumor xenograft dissociation for the profiling of cell surface markers and nutrient transporters
Petit V, Massonnet G, Maciorowski Z, Touhami J, Thuleau A, Némati F, Laval J, Château-Joubert S, Servely J, Vallerand D, Fontaine J, Taylor N, Battini J, Sitbon M, Decaudin D
Laboratory Investigation 2013;93(5):611-621
Laboratory Investigation 2013;93(5):611-621
Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay
Baccelli I, Schneeweiss A, Riethdorf S, Stenzinger A, Schillert A, Vogel V, Klein C, Saini M, Bäuerle T, Wallwiener M, Holland-Letz T, Höfner T, Sprick M, Scharpff M, Marmé F, Sinn H, Pantel K, Weichert W, Trumpp A
Nature Biotechnology 2013;31(6):539-544
Nature Biotechnology 2013;31(6):539-544
Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status.
Vazquez-Martin A, Oliveras-Ferraros C, Cufí S, Del Barco S, Martin-Castillo B, Menendez JA
Cell cycle (Georgetown, Tex.) 2010 Sep 15;9(18):3807-14
Cell cycle (Georgetown, Tex.) 2010 Sep 15;9(18):3807-14
Synthesis of hyaluronan in oesophageal cancer cells is uncoupled from the prostaglandin–cAMP pathway
Twarock S, Röck K, Sarbia M, Weber A, Jänicke R, Fischer J
British Journal of Pharmacology 2009;157(2):234-243
British Journal of Pharmacology 2009;157(2):234-243
Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma
Asplund A, Gry Björklund M, Sundquist C, Strömberg S, Edlund K, Östman A, Nilsson P, Pontén F, Lundeberg J
British Journal of Dermatology 2008;158(3):527-538
British Journal of Dermatology 2008;158(3):527-538
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human skin and skeletal muscle tissues using HPA005785 antibody. Corresponding CD44 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
