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- Antigen structure
- References [52]
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- Product number
- 21775-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21775-1-AP, RRID:AB_10734593
- Product name
- IFIH1/MDA5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IFIH1/MDA5 antibody (Cat. #21775-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hyperacetylated microtubules assist porcine deltacoronavirus nsp8 to degrade MDA5 via SQSTM1/p62-dependent selective autophagy.
Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.
Histone H1.2 Inhibited EMCV Replication through Enhancing MDA5-Mediated IFN-β Signaling Pathway.
Transcriptome-Wide N6-Methyladenosine Alternations in Pulmonary Arteries of Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats and Novel Therapeutic Targets.
Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition.
Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response.
IFNα-induced BST2(+) tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling.
A tale of two tumors: differential, but detrimental, effects of glioblastoma extracellular vesicles (EVs) on normal human brain cells.
IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages.
ADAR1 links R-loop homeostasis to ATR activation in replication stress response.
Incorporation of 5 methylcytidine alleviates innate immune response to self-amplifying RNA vaccine.
CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.
IFITM2 Presents Antiviral Response through Enhancing Type I IFN Signaling Pathway.
Porcine Epidemic Diarrhea Virus nsp7 Inhibits MDA5 Dephosphorylation to Antagonize Type I Interferon Production.
Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses.
STAT3 regulates antiviral immunity by suppressing excessive interferon signaling.
LGP2 Promotes Type I Interferon Production To Inhibit PRRSV Infection via Enhancing MDA5-Mediated Signaling.
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection.
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
A genome-wide optical pooled screen reveals regulators of cellular antiviral responses.
Systematic Analysis of Molecular Subtypes Based on the Expression Profile of Immune-Related Genes in Pancreatic Cancer.
CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses.
Peste des Petits Ruminants Virus Upregulates STING to Activate ATF6-Mediated Autophagy.
Direct Interaction of Coronavirus Nonstructural Protein 3 with Melanoma Differentiation-Associated Gene 5 Modulates Type I Interferon Response during Coronavirus Infection.
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses.
RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency.
Impaired Antiviral Responses to Extracellular Double-Stranded RNA and Cytosolic DNA, but Not to Interferon-α Stimulation, in TRIM56-Deficient Cells.
STING1 is essential for an RNA-virus triggered autophagy.
HSP27 Protein Dampens Encephalomyocarditis Virus Replication by Stabilizing Melanoma Differentiation-Associated Gene 5.
Constitutive TRIM22 Expression in the Respiratory Tract Confers a Pre-Existing Defence Against Influenza A Virus Infection.
Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion.
Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation.
Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses.
Murine norovirus replicase augments RIG-I-like receptors-mediated antiviral interferon response.
ALS-associated genes in SCA2 mouse spinal cord transcriptomes.
Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response.
ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress.
Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy.
Ribosome biogenesis restricts innate immune responses to virus infection and DNA.
MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation.
Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-Induced Innate Immunity.
RNA m(6) A modification enzymes shape innate responses to DNA by regulating interferon β.
HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction.
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
ARRDC4 regulates enterovirus 71-induced innate immune response by promoting K63 polyubiquitination of MDA5 through TRIM65.
TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity.
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism.
Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins.
Li Z, Lai Y, Qiu R, Tang W, Ren J, Xiao S, Fang P, Fang L
Journal of virology 2024 Mar 19;98(3):e0000324
Journal of virology 2024 Mar 19;98(3):e0000324
Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.
Li D, Mo R, Li X, Cheng R, Xie J, Li H, Yang Y, Li S, Li H, Yan Z, Wei S, Idris A, Li X, Feng R
mSphere 2024 Jun 25;9(6):e0023624
mSphere 2024 Jun 25;9(6):e0023624
Histone H1.2 Inhibited EMCV Replication through Enhancing MDA5-Mediated IFN-β Signaling Pathway.
Song Y, Li H, Lian R, Dou X, Li S, Xie J, Li X, Feng R, Li Z
Viruses 2024 Jan 24;16(2)
Viruses 2024 Jan 24;16(2)
Transcriptome-Wide N6-Methyladenosine Alternations in Pulmonary Arteries of Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats and Novel Therapeutic Targets.
Feng Y, Yu Z, Tang M, Li J, Peng B, Juaiti M, Tang Y, Liang B, Ouyang M, Liu Q, Song J
Biomedicines 2024 Feb 4;12(2)
Biomedicines 2024 Feb 4;12(2)
Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition.
Li Y, Shen S, Guo H, Li H, Zhang L, Zhang B, Yu XF, Wei W
Cell reports 2024 Feb 27;43(2):113749
Cell reports 2024 Feb 27;43(2):113749
Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response.
Li ZA, Bajpai AK, Wang R, Liu Y, Webby RJ, Wilk E, Gu W, Schughart K, Li K, Lu L
Virus research 2024 Apr;342:199335
Virus research 2024 Apr;342:199335
IFNα-induced BST2(+) tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling.
Zheng C, Wang J, Zhou Y, Duan Y, Zheng R, Xie Y, Wei X, Wu J, Shen H, Ye M, Kong B, Liu Y, Xu P, Zhang Q, Liang T
Cell reports 2024 Apr 23;43(4):114088
Cell reports 2024 Apr 23;43(4):114088
A tale of two tumors: differential, but detrimental, effects of glioblastoma extracellular vesicles (EVs) on normal human brain cells.
Wang M, Graner AN, Knowles B, McRae C, Fringuello A, Paucek P, Gavrilovic M, Redwine M, Hanson C, Coughlan C, Metzger B, Bolus V, Kopper T, Smith M, Zhou W, Lenz M, Abosch A, Ojemann S, Lillehei KO, Yu X, Graner MW
bioRxiv : the preprint server for biology 2024 Apr 12;
bioRxiv : the preprint server for biology 2024 Apr 12;
IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages.
Aparici-Herraiz I, Sánchez-Sánchez G, Batlle C, Rehues P, López-Serrat M, Valverde-Estrella L, Lloberas J, Celada A
Journal of innate immunity 2023;15(1):297-316
Journal of innate immunity 2023;15(1):297-316
ADAR1 links R-loop homeostasis to ATR activation in replication stress response.
Zhang B, Li Y, Zhang J, Wang Y, Liang C, Lu T, Zhang C, Liu L, Qin Y, He J, Zhao X, Yu J, Hao J, Yang J, Li MJ, Yao Z, Ma S, Cheng H, Cheng T, Shi L
Nucleic acids research 2023 Nov 27;51(21):11668-11687
Nucleic acids research 2023 Nov 27;51(21):11668-11687
Incorporation of 5 methylcytidine alleviates innate immune response to self-amplifying RNA vaccine.
Komori M, Morey AL, Quiñones-Molina AA, Fofana J, Romero L, Peters E, Matsuda K, Gummuluru S, Smith JF, Akahata W, Akiyama H
bioRxiv : the preprint server for biology 2023 Nov 1;
bioRxiv : the preprint server for biology 2023 Nov 1;
CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.
Yi J, Wang L, Hu GS, Zhang YY, Du J, Ding JC, Ji X, Shen HF, Huang HH, Ye F, Liu W
The EMBO journal 2023 May 15;42(10):e112408
The EMBO journal 2023 May 15;42(10):e112408
IFITM2 Presents Antiviral Response through Enhancing Type I IFN Signaling Pathway.
Chen L, Li X, Deng Y, Bi Y, Yan Z, Yang Y, Zhang X, Li H, Xie J, Feng R
Viruses 2023 Mar 28;15(4)
Viruses 2023 Mar 28;15(4)
Porcine Epidemic Diarrhea Virus nsp7 Inhibits MDA5 Dephosphorylation to Antagonize Type I Interferon Production.
Zhang J, Fang P, Ren J, Xia S, Zhang H, Zhu X, Ding T, Xiao S, Fang L
Microbiology spectrum 2023 Mar 28;11(2):e0501722
Microbiology spectrum 2023 Mar 28;11(2):e0501722
Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses.
Deng S, He W, Gong AY, Li M, Wang Y, Xia Z, Zhang XT, Huang Pacheco AS, Naqib A, Jenkins M, Swanson PC, Drescher KM, Strauss-Soukup JK, Belshan M, Chen XM
Nature communications 2023 Mar 16;14(1):1456
Nature communications 2023 Mar 16;14(1):1456
STAT3 regulates antiviral immunity by suppressing excessive interferon signaling.
Liu S, Liu S, Yu Z, Zhou W, Zheng M, Gu R, Hong J, Yang Z, Chi X, Guo G, Li X, Chen N, Huang S, Wang S, Chen JL
Cell reports 2023 Jul 25;42(7):112806
Cell reports 2023 Jul 25;42(7):112806
LGP2 Promotes Type I Interferon Production To Inhibit PRRSV Infection via Enhancing MDA5-Mediated Signaling.
Zhu Z, Zhang M, Yuan L, Xu Y, Zhou H, Lian Z, Liu P, Li X
Journal of virology 2023 Jan 31;97(1):e0184322
Journal of virology 2023 Jan 31;97(1):e0184322
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
Zheng W, Zhou Z, Rui Y, Ye R, Xia F, Guo F, Liu X, Su J, Lou M, Yu XF
Signal transduction and targeted therapy 2023 Feb 24;8(1):79
Signal transduction and targeted therapy 2023 Feb 24;8(1):79
CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection.
Burgess HM, Grande R, Riccio S, Dinesh I, Winkler GS, Depledge DP, Mohr I
EMBO reports 2023 Dec 6;24(12):e56327
EMBO reports 2023 Dec 6;24(12):e56327
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
Tang F, Lu C, He X, Lin W, Xie B, Gao X, Peng Y, Yang D, Sun L, Weng L
Cell reports 2023 Dec 26;42(12):113477
Cell reports 2023 Dec 26;42(12):113477
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus.
Guney MH, Nagalekshmi K, McCauley SM, Carbone C, Aydemir O, Luban J
bioRxiv : the preprint server for biology 2023 Dec 12;
bioRxiv : the preprint server for biology 2023 Dec 12;
A genome-wide optical pooled screen reveals regulators of cellular antiviral responses.
Carlson RJ, Leiken MD, Guna A, Hacohen N, Blainey PC
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 18;120(16):e2210623120
Proceedings of the National Academy of Sciences of the United States of America 2023 Apr 18;120(16):e2210623120
Systematic Analysis of Molecular Subtypes Based on the Expression Profile of Immune-Related Genes in Pancreatic Cancer.
Ke M
Oxidative medicine and cellular longevity 2022;2022:3124122
Oxidative medicine and cellular longevity 2022;2022:3124122
CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses.
Jalloh S, Olejnik J, Berrigan J, Nisa A, Suder EL, Akiyama H, Lei M, Ramaswamy S, Tyagi S, Bushkin Y, Mühlberger E, Gummuluru S
PLoS pathogens 2022 Oct;18(10):e1010479
PLoS pathogens 2022 Oct;18(10):e1010479
Peste des Petits Ruminants Virus Upregulates STING to Activate ATF6-Mediated Autophagy.
Zhang R, Lin H, You Q, Zhang Z, Bai L, Chen F, Zhu X, Zhang Z, Li Y
Journal of virology 2022 Oct 26;96(20):e0137522
Journal of virology 2022 Oct 26;96(20):e0137522
Direct Interaction of Coronavirus Nonstructural Protein 3 with Melanoma Differentiation-Associated Gene 5 Modulates Type I Interferon Response during Coronavirus Infection.
Sun X, Quan L, Chen R, Liu D
International journal of molecular sciences 2022 Oct 2;23(19)
International journal of molecular sciences 2022 Oct 2;23(19)
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Hiatt JB, Sandborg H, Garrison SM, Arnold HU, Liao SY, Norton JP, Friesen TJ, Wu F, Sutherland KD, Rienhoff HY, Martins R, Houghton AM, Srivastava S, MacPherson D
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Oct 14;28(20):4551-4564
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 Oct 14;28(20):4551-4564
CD169-mediated restrictive SARS-CoV-2 infection of macrophages induces pro-inflammatory responses.
Jalloh S, Olejnik J, Berrigan J, Nisa A, Suder EL, Akiyama H, Lei M, Tyagi S, Bushkin Y, Mühlberger E, Gummuluru S
bioRxiv : the preprint server for biology 2022 Mar 30;
bioRxiv : the preprint server for biology 2022 Mar 30;
RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency.
Stok JE, Oosenbrug T, Ter Haar LR, Gravekamp D, Bromley CP, Zelenay S, Reis e Sousa C, van der Veen AG
The EMBO journal 2022 Mar 15;41(6):e109760
The EMBO journal 2022 Mar 15;41(6):e109760
Impaired Antiviral Responses to Extracellular Double-Stranded RNA and Cytosolic DNA, but Not to Interferon-α Stimulation, in TRIM56-Deficient Cells.
Wang D, Wang R, Li K
Viruses 2022 Jan 5;14(1)
Viruses 2022 Jan 5;14(1)
STING1 is essential for an RNA-virus triggered autophagy.
Zhang R, Qin X, Yang Y, Zhu X, Zhao S, Zhang Z, Su Q, Zhao Z, Yin X, Meng X, Zhang Z, Li Y
Autophagy 2022 Apr;18(4):816-828
Autophagy 2022 Apr;18(4):816-828
HSP27 Protein Dampens Encephalomyocarditis Virus Replication by Stabilizing Melanoma Differentiation-Associated Gene 5.
Li X, Ma R, Wu B, Niu Y, Li H, Li D, Xie J, Idris A, Feng R
Frontiers in microbiology 2021;12:788870
Frontiers in microbiology 2021;12:788870
Constitutive TRIM22 Expression in the Respiratory Tract Confers a Pre-Existing Defence Against Influenza A Virus Infection.
Charman M, McFarlane S, Wojtus JK, Sloan E, Dewar R, Leeming G, Al-Saadi M, Hunter L, Carroll MW, Stewart JP, Digard P, Hutchinson E, Boutell C
Frontiers in cellular and infection microbiology 2021;11:689707
Frontiers in cellular and infection microbiology 2021;11:689707
Curcumol inhibits encephalomyocarditis virus by promoting IFN-β secretion.
Zheng J, Xu Y, Khan A, Sun P, Sun Y, Fan K, Yin W, Wang S, Li H, Sun N
BMC veterinary research 2021 Sep 30;17(1):318
BMC veterinary research 2021 Sep 30;17(1):318
Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation.
Shen Y, Tang K, Chen D, Hong M, Sun F, Wang S, Ke Y, Wu T, Sun R, Qian J, Du Y
Cell reports 2021 Jun 22;35(12):109272
Cell reports 2021 Jun 22;35(12):109272
Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses.
Mikhalkevich N, O'Carroll IP, Tkavc R, Lund K, Sukumar G, Dalgard CL, Johnson KR, Li W, Wang T, Nath A, Iordanskiy S
PLoS pathogens 2021 Feb;17(2):e1009305
PLoS pathogens 2021 Feb;17(2):e1009305
Murine norovirus replicase augments RIG-I-like receptors-mediated antiviral interferon response.
Yu P, Li Y, Li Y, Miao Z, Wang Y, Peppelenbosch MP, Pan Q
Antiviral research 2020 Oct;182:104877
Antiviral research 2020 Oct;182:104877
ALS-associated genes in SCA2 mouse spinal cord transcriptomes.
Scoles DR, Dansithong W, Pflieger LT, Paul S, Gandelman M, Figueroa KP, Rigo F, Bennett CF, Pulst SM
Human molecular genetics 2020 Jun 27;29(10):1658-1672
Human molecular genetics 2020 Jun 27;29(10):1658-1672
Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response.
Dhanwani R, Takahashi M, Mathews IT, Lenzi C, Romanov A, Watrous JD, Pieters B, Hedrick CC, Benedict CA, Linden J, Nilsson R, Jain M, Sharma S
Science advances 2020 Jul;6(30):eaba3688
Science advances 2020 Jul;6(30):eaba3688
ADAR1-Dependent RNA Editing Promotes MET and iPSC Reprogramming by Alleviating ER Stress.
Guallar D, Fuentes-Iglesias A, Souto Y, Ameneiro C, Freire-Agulleiro O, Pardavila JA, Escudero A, Garcia-Outeiral V, Moreira T, Saenz C, Xiong H, Liu D, Xiao S, Hou Y, Wu K, Torrecilla D, Hartner JC, Blanco MG, Lee LJ, López M, Walkley CR, Wang J, Fidalgo M
Cell stem cell 2020 Aug 6;27(2):300-314.e11
Cell stem cell 2020 Aug 6;27(2):300-314.e11
Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy.
Lee AK, Pan D, Bao X, Hu M, Li F, Li CY
Radiation research 2020 Apr;193(4):305-317
Radiation research 2020 Apr;193(4):305-317
Ribosome biogenesis restricts innate immune responses to virus infection and DNA.
Bianco C, Mohr I
eLife 2019 Dec 16;8
eLife 2019 Dec 16;8
MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation.
Zhou P, Ding X, Wan X, Liu L, Yuan X, Zhang W, Hui X, Meng G, Xiao H, Li B, Zhong J, Hou F, Deng L, Zhang Y
Nature communications 2018 Mar 28;9(1):1243
Nature communications 2018 Mar 28;9(1):1243
Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-Induced Innate Immunity.
Shang J, Xia T, Han QQ, Zhao X, Hu MM, Shu HB, Guo L
Proteomics 2018 Jan;18(2)
Proteomics 2018 Jan;18(2)
RNA m(6) A modification enzymes shape innate responses to DNA by regulating interferon β.
Rubio RM, Depledge DP, Bianco C, Thompson L, Mohr I
Genes & development 2018 Dec 1;32(23-24):1472-1484
Genes & development 2018 Dec 1;32(23-24):1472-1484
HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction.
Akiyama H, Miller CM, Ettinger CR, Belkina AC, Snyder-Cappione JE, Gummuluru S
Nature communications 2018 Aug 27;9(1):3450
Nature communications 2018 Aug 27;9(1):3450
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
Burgess HM, Mohr I
Journal of virology 2018 Aug 1;92(15)
Journal of virology 2018 Aug 1;92(15)
ARRDC4 regulates enterovirus 71-induced innate immune response by promoting K63 polyubiquitination of MDA5 through TRIM65.
Meng J, Yao Z, He Y, Zhang R, Zhang Y, Yao X, Yang H, Chen L, Zhang Z, Zhang H, Bao X, Hu G, Wu T, Cheng J
Cell death & disease 2017 Jun 8;8(6):e2866
Cell death & disease 2017 Jun 8;8(6):e2866
TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity.
Lang X, Tang T, Jin T, Ding C, Zhou R, Jiang W
The Journal of experimental medicine 2017 Feb;214(2):459-473
The Journal of experimental medicine 2017 Feb;214(2):459-473
Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus.
Zhang LK, Xin QL, Zhu SL, Wan WW, Wang W, Xiao G
Journal of virology 2016 Nov 15;90(22):10259-10270
Journal of virology 2016 Nov 15;90(22):10259-10270
The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism.
Wang Y, Liu L
mBio 2016 Feb 9;7(1):e01872-15
mBio 2016 Feb 9;7(1):e01872-15
Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins.
Zhang W, Zhang L, Zan Y, Du N, Yang Y, Tien P
The Journal of general virology 2015 Jan;96(Pt 1):170-182
The Journal of general virology 2015 Jan;96(Pt 1):170-182
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IFIH1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IFIH1. This antibody recognizes human antigen. The IFIH1 antibody has been validated for the following applications: ELISA, WB analysis.
