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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500266 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Interferon Induced with Helicase C Domain 1 (IFIH1) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- MDA5 antibody was raised against a 16 amino acid peptide from near the center of humanMDA5.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses.
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.
Pathogen recognition and innate immunity.
Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter.
Surface-embedded Green-function method for general surfaces: Application to Al(111).
Hiscott J, Nguyen TL, Arguello M, Nakhaei P, Paz S
Oncogene 2006 Oct 30;25(51):6844-67
Oncogene 2006 Oct 30;25(51):6844-67
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.
Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, Matsui K, Uematsu S, Jung A, Kawai T, Ishii KJ, Yamaguchi O, Otsu K, Tsujimura T, Koh CS, Reis e Sousa C, Matsuura Y, Fujita T, Akira S
Nature 2006 May 4;441(7089):101-5
Nature 2006 May 4;441(7089):101-5
Pathogen recognition and innate immunity.
Akira S, Uematsu S, Takeuchi O
Cell 2006 Feb 24;124(4):783-801
Cell 2006 Feb 24;124(4):783-801
Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene.
Kang DC, Gopalkrishnan RV, Lin L, Randolph A, Valerie K, Pestka S, Fisher PB
Oncogene 2004 Mar 4;23(9):1789-800
Oncogene 2004 Mar 4;23(9):1789-800
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter.
Andrejeva J, Childs KS, Young DF, Carlos TS, Stock N, Goodbourn S, Randall RE
Proceedings of the National Academy of Sciences of the United States of America 2004 Dec 7;101(49):17264-9
Proceedings of the National Academy of Sciences of the United States of America 2004 Dec 7;101(49):17264-9
Surface-embedded Green-function method for general surfaces: Application to Al(111).
Benesh GA, Liyanage LS
Physical review. B, Condensed matter 1994 Jun 15;49(24):17264-17272
Physical review. B, Condensed matter 1994 Jun 15;49(24):17264-17272
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of MDA5 in Daudi cell lysate with MDA5 antibody Cat.-No AP30554PU-N at (A) 1, (B) 2 and (C) 4 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence of MDA5 in Human Lymph Node cells with MDA5 antibody Cat.-No AP30554PU-N at 20 mg/ml
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of MDA5 in human lymph node tissue with MDA5 antibody Cat.-No AP30554PU-N at 5 ?g/ml.
