CABT-L1645

antibody from Creative Diagnostics

Targeting: TRAF1 EBI6

No application information provided.

Antibody Data

Product number

CABT-L1645

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human TRAF1 monoclonal antibody, clone L.026.20

Antibody type

Monoclonal

Description

The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins