11090-1-AP

antibody from Proteintech Group

Targeting: DNAJC7 TPR2, TTC2

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

11090-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#11090-1-AP, RRID:AB_2293179

Product name

DNAJC7 antibody

Antibody type

Polyclonal

Description

KD/KO validated DNAJC7 antibody (Cat. #11090-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB, ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Microcephaly-associated protein WDR62 supports purine metabolism by interacting with co-chaperone BAG2.

Morris MJ, Yeap YY, Edwards JR, Chen C, Paolino A, Furness SGB, Millard SS, Pagan JK, Fenlon LR, Ng DCH
The EMBO journal 2026 Apr;45(7):2157-2181

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The Hsp40 cochaperone DNAJC7 regulates polyglutamine aggregation and exhibits context-dependent effects on polyglycine aggregation.

Ramani B, Ehsani K, Kampmann M
The Journal of biological chemistry 2026 Apr;302(4):111292

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The Hsp40 co-chaperone DNAJC7 modifies polyglutamine but not polyglycine aggregation.

Ramani B, Ehsani K, Kampmann M
bioRxiv : the preprint server for biology 2025 Aug 12;

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DnaJC7 specifically regulates tau seeding.

Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL 3rd, Joachimiak LA, Diamond MI
bioRxiv : the preprint server for biology 2023 Mar 16;

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DnaJC7 specifically regulates tau seeding.

Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL, Joachimiak LA, Diamond MI
eLife 2023 Jun 30;12

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ALS-linked loss of Cyclin-F function affects HSP90.

Siebert A, Gattringer V, Weishaupt JH, Behrends C
Life science alliance 2022 Sep 16;5(12)

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Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin.

Alalem M, Bhosale M, Ranjan A, Yamamoto S, Kaida A, Nishikawa S, Parrales A, Farooki S, Anant S, Padhye S, Iwakuma T
Cancers 2022 Aug 29;14(17)

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DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation.

Hou Z, Wydorski PM, Perez VA, Mendoza-Oliva A, Ryder BD, Mirbaha H, Kashmer O, Joachimiak LA
Nature communications 2021 Sep 9;12(1):5338

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Indirect activation of constitutive androstane receptor in three-dimensionally cultured HepG2 cells.

Yokobori K, Azuma I, Chiba K, Akita H, Furihata T, Kobayashi K
Biochemical pharmacology 2019 Oct;168:26-37

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Co-chaperon DnaJC7/TPR2 enhances p53 stability and activity through blocking the complex formation between p53 and MDM2.

Kubo N, Wu D, Yoshihara Y, Sang M, Nakagawara A, Ozaki T
Biochemical and biophysical research communications 2013 Jan 18;430(3):1034-9

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Jurkat cells were subjected to SDS PAGE followed by western blot with 11090-1-AP(DNAJC7 antibody) at dilution of 1:500

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using DNAJC7 antibody 11090-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human pancreas cancer using 11090-1-AP(DNAJC7 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue