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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA019462 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA019462, RRID:AB_1847595
- Product name
- Anti-DEFA6
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human DEFA6, Gene description: defensin, alpha 6, Paneth cell-specific, Alternative Gene Names: DEF6, HD-6, Validated applications: IHC, WB, Uniprot ID: Q01524, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Development of Human Gut Organoids With Resident Tissue Macrophages as a Model of Intestinal Immune Responses
Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn’s disease
A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells
REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation
Macaque Paneth Cells Express Lymphoid Chemokine CXCL13 and Other Antimicrobial Peptides Not Previously Described as Expressed in Intestinal Crypts
Activation of REG family proteins in colitis
Tsuruta S, Kawasaki T, Machida M, Iwatsuki K, Inaba A, Shibata S, Shindo T, Nakabayashi K, Hakamada K, Umezawa A, Akutsu H
Cellular and Molecular Gastroenterology and Hepatology 2022;14(3):726-729.e5
Cellular and Molecular Gastroenterology and Hepatology 2022;14(3):726-729.e5
Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn’s disease
Thorsvik S, Bakke I, van Beelen Granlund A, Røyset E, Damås J, Østvik A, Sandvik A
Cell and Tissue Research 2018;374(2):339-348
Cell and Tissue Research 2018;374(2):339-348
A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells
Uchida H, Machida M, Miura T, Kawasaki T, Okazaki T, Sasaki K, Sakamoto S, Ohuchi N, Kasahara M, Umezawa A, Akutsu H
JCI Insight 2017;2(1)
JCI Insight 2017;2(1)
REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation
van Beelen Granlund A, Østvik A, Brenna Ø, Torp S, Gustafsson B, Sandvik A
Cell and Tissue Research 2013;352(3):639-646
Cell and Tissue Research 2013;352(3):639-646
Macaque Paneth Cells Express Lymphoid Chemokine CXCL13 and Other Antimicrobial Peptides Not Previously Described as Expressed in Intestinal Crypts
Lucero C, Fallert Junecko B, Klamar C, Sciullo L, Berendam S, Cillo A, Qin S, Sui Y, Sanghavi S, Murphey-Corb M, Reinhart T
Clinical and Vaccine Immunology 2013;20(8):1320-1328
Clinical and Vaccine Immunology 2013;20(8):1320-1328
Activation of REG family proteins in colitis
Granlund A, Beisvag V, Torp S, Flatberg A, Kleveland P, Østvik A, Waldum H, Sandvik A
Scandinavian Journal of Gastroenterology 2011;46(11):1316-1323
Scandinavian Journal of Gastroenterology 2011;46(11):1316-1323
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human small intestine and cerebral cortex tissues using HPA019462 antibody. Corresponding DEFA6 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
