PA5-71105

antibody from Invitrogen Antibodies

Targeting: FAM171A2 MGC34829

Western blot (Recommended by provider)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-71105

Provider

Invitrogen Antibodies

Product name

FAM171A2 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

This target displays homology in the following species: Cow: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

0.5 mg/mL

Storage

-20° C, Avoid Freeze/Thaw Cycles

References

Submitted references

Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer.

Apóstolo N, Smukowski SN, Vanderlinden J, Condomitti G, Rybakin V, Ten Bos J, Trobiani L, Portegies S, Vennekens KM, Gounko NV, Comoletti D, Wierda KD, Savas JN, de Wit J
Nature communications 2020 Oct 14;11(1):5171

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Fig. 2 Dissection of MF synapse CSP composition. a Protein functional classes represented in the group of CSPs identified in isolated MF synaptosomes. b Occurrence of protein domains among identified CSPs. c SynGO cellular component analysis of CSP genes (75) and respective CSPs (77). Discrepancy between gene number and CSP number is related to NRXN isoforms. Proteins with unknown function in the brain are highlighted in bold with an asterisk: APMAP, BRINP2, FAM171A2, and IgSF8. d Validation of 15 CSPs in sorted MF synaptosomes by western blot, including BRINP2 and IgSF8, CSPs without a known function in the brain. e Confocal images of P28 mouse hippocampal sections immunostained for 15 CSPs showing a striking laminar distribution to the SL. Of the CSPs without a known function in the brain, IgSF8 showed strong labeling in the MF pathway. Source data are provided as a Source data file. Scale bar in e 200 mum.