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- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- NBP1-20989 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-20989, RRID:AB_1643238
- Product name
- Goat Polyclonal TRPC4 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This antibody is expected to recognise all six reported isoforms (NP_057263.1
- Reactivity
- Human, Rat
- Host
- Goat
- Antigen sequence
C terminus- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility.
Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture.
Abou-Saleh H, Pathan AR, Daalis A, Hubrack S, Abou-Jassoum H, Al-Naeimi H, Rusch NJ, Machaca K
The Journal of biological chemistry 2013 Nov 15;288(46):32941-51
The Journal of biological chemistry 2013 Nov 15;288(46):32941-51
Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture.
Song X, Zhao Y, Narcisse L, Duffy H, Kress Y, Lee S, Brosnan CF
Glia 2005 Feb;49(3):418-29
Glia 2005 Feb;49(3):418-29
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TRPC4 Antibody [NBP1-20989] - (0.3ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TRPC4 Antibody [NBP1-20989] - (4.75ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TRPC4 Antibody [NBP1-20989] - (4.75ug/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
