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PLCD3
Phospholipase C delta 3This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| NSJ Bioreagents |  RQ7952 |
Polyclonal |
WB
EL
ICC
FC
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| Proteintech Group | 16792-1-AP |
2 references | Polyclonal |
WB
EL
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| Biorbyt | orb1676217 |
Polyclonal |
WB
EL
ICC
FC
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| antibodies-online | ABIN4346117 |
Polyclonal |
WB
ICC
IHC
|
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| Antibodies.com | A326279 |
Polyclonal |
WB
EL
IHC
|
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