PLCD3

gene product
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
89 antibodies from 22 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
18 antibodies
Novus Biologicals
3 antibodies
Invitrogen Antibodies
3 antibodies
Atlas Antibodies
2 antibodies
Abnova Corporation
1 antibody
GeneTex
1 antibody
NovoPro Bioscience Inc.
2 antibodies
Proteintech Group
1 antibody
LifeSpan BioSciences, Inc.
24 antibodies
Biorbyt
6 antibodies
Abgent
1 antibody
Acris Antibodies GmbH
1 antibody
Aviva Systems Biology
1 antibody
Creative Biolabs
1 antibody
OriGene
1 antibody
R&D Systems
1 antibody
St John's Laboratory
1 antibody
Creative Diagnostics
3 antibodies
MyBioSource
2 antibodies
Sigma-Aldrich
1 antibody
United States Biological
14 antibodies
ProSci
1 antibody