HPA021679
antibody from Atlas Antibodies
		Targeting: CHAF1B
		
		CAF-1, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7	
	
	
	
	
Antibody data
- Antibody Data
 - Antigen structure
 - References [3]
 - Comments [0]
 - Validations
 - Immunocytochemistry [1]
 
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Validation data
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- Product number
 - HPA021679 - Provider product page

 - Provider
 - Atlas Antibodies
 - Proper citation
 - Atlas Antibodies Cat#HPA021679, RRID:AB_1846621
 - Product name
 - Anti-CHAF1B
 - Antibody type
 - Polyclonal
 - Description
 - Polyclonal Antibody against Human CHAF1B, Gene description: chromatin assembly factor 1, subunit B (p60), Alternative Gene Names: CAF-1, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7, Validated applications: ICC, IHC, WB, Uniprot ID: Q13112, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
 - Reactivity
 - Human
 - Host
 - Rabbit
 - Conjugate
 - Unconjugated
 - Isotype
 - IgG
 - Vial size
 - 100 µl
 - Concentration
 - 0.1 mg/ml
 - Storage
 - Store at +4°C for short term storage. Long time storage is recommended at -20°C.
 - Handling
 - The antibody solution should be gently mixed before use.
 
Submitted references		NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis
				
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
				
CAF-1 Subunits Levels Suggest Combined Treatments with PARP-Inhibitors and Ionizing Radiation in Advanced HNSCC
				
		
	
			Ilter D, Drapela S, Schild T, Ward N, Adhikari E, Low V, Asara J, Oskarsson T, Lau E, DeNicola G, McReynolds M, Gomes A
Redox Biology 2023;61
		Redox Biology 2023;61
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
			Gomes A, Ilter D, Low V, Rosenzweig A, Shen Z, Schild T, Rivas M, Er E, McNally D, Mutvei A, Han J, Ou Y, Cavaliere P, Mullarky E, Nagiec M, Shin S, Yoon S, Dephoure N, Massagué J, Melnick A, Cantley L, Tyler J, Blenis J
Cancer Cell 2019;36(4):402-417.e13
		Cancer Cell 2019;36(4):402-417.e13
CAF-1 Subunits Levels Suggest Combined Treatments with PARP-Inhibitors and Ionizing Radiation in Advanced HNSCC
			Morra F, Merolla F, Picardi I, Russo D, Ilardi G, Varricchio S, Liotti F, Pacelli R, Palazzo L, Mascolo M, Celetti A, Staibano S
Cancers 2019;11(10):1582
		Cancers 2019;11(10):1582
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					Supportive validation
					
									
				
		- Submitted by
 - Atlas Antibodies (provider)
 - Main image
 
- Experimental details
 - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
 - Sample type
 - Human