CABT-L1299
antibody from Creative Diagnostics
Targeting: FERMT1
C20orf42, FLJ20116, KIND1, UNC112A, URP1
Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-L1299 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-Human Kindlin 1 monoclonal antibody, clone 8I8M0
- Antibody type
- Monoclonal
- Description
- Kindlin 1 is a member of the kindlin family of focal adhesion proteins and contains a FERM domain and pleckstrin homology domain. It is involved in integrin signaling, linkage of the cytoskeleton to the extracellular matrix, and cell adhesion. It is most often expressed in epithelial cells. When kindlin 1 is coexpressed with talin it helps to activate ITGA2B. It is required for keratinocyte proliferation, polarization of basal keratinocytes in the skin, and for normal cell shape. Mutations in kindlin 1 have been linked to Kindler syndrome, a recessive skin disorder involving blistering, photosensitivity, poikiloderma, and atrophy.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 8I8M0
- Concentration
- 0.5 mg/ml
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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