Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10062-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10062-2-AP, RRID:AB_2153338
- Product name
- Notch1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Notch1 antibody (Cat. #10062-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Screening and identification of NOTCH1, CDKN2A, and NOS3 as differentially expressed autophagy-related genes in erectile dysfunction.
Lipoxin A4 regulates microglial M1/M2 polarization after cerebral ischemia-reperfusion injury via the Notch signaling pathway.
Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury.
POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling.
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Potential role of the Jagged1/Notch1 signaling pathway in the endothelial-myofibroblast transition during BLM-induced pulmonary fibrosis.
The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats.
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Thymosin beta 4 silencing suppresses proliferation and invasion of non-small cell lung cancer cells by repressing Notch1 activation.
Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth.
TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.
Neuropathological and biochemical assessments of an Alzheimer's disease patient treated with the γ-secretase inhibitor semagacestat.
Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/β-catenin pathway.
Luo C, Zhou X, Wang L, Zeng Q, Fan J, He S, Zhang H, Wei A
PeerJ 2021;9:e11986
PeerJ 2021;9:e11986
Lipoxin A4 regulates microglial M1/M2 polarization after cerebral ischemia-reperfusion injury via the Notch signaling pathway.
Li QQ, Ding DH, Wang XY, Sun YY, Wu J
Experimental neurology 2021 May;339:113645
Experimental neurology 2021 May;339:113645
Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.
Hou HW, Xue P, Wang Y, Li YK
European review for medical and pharmacological sciences 2020 Dec;24(23):12408-12422
European review for medical and pharmacological sciences 2020 Dec;24(23):12408-12422
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury.
Zhang HM, Liu P, Jiang C, Jin XQ, Liu RN, Li SQ, Zhao Y
PloS one 2018;13(2):e0193037
PloS one 2018;13(2):e0193037
POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling.
Du Y, Li D, Li N, Su C, Yang C, Lin C, Chen M, Wu R, Li X, Hu G
Cell death & disease 2018 Sep 24;9(10):995
Cell death & disease 2018 Sep 24;9(10):995
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Yin LL, Wen XM, Li M, Xu YM, Zhao XF, Li J, Wang XW
Oncology letters 2018 Nov;16(5):6283-6292
Oncology letters 2018 Nov;16(5):6283-6292
Potential role of the Jagged1/Notch1 signaling pathway in the endothelial-myofibroblast transition during BLM-induced pulmonary fibrosis.
Yin Q, Wang W, Cui G, Yan L, Zhang S
Journal of cellular physiology 2018 Mar;233(3):2451-2463
Journal of cellular physiology 2018 Mar;233(3):2451-2463
The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats.
Gong C, Li L, Qin C, Wu W, Liu Q, Li Y, Gan L, Ou S
Journal of diabetes research 2017;2017:8968523
Journal of diabetes research 2017;2017:8968523
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, Wei X, Zhang Y, Sun Y, Zhou Z, Su H, Zhang C, Li N, Gao C, Peng J, Yi F
Nature communications 2017 Sep 4;8(1):413
Nature communications 2017 Sep 4;8(1):413
Fbw7 regulates apoptosis in activated B-cell like diffuse large B-cell lymphoma by targeting Stat3 for ubiquitylation and degradation.
Yao S, Xu F, Chen Y, Ge Y, Zhang F, Huang H, Li L, Lin D, Luo X, Xu J, Luo D, Zhu X, Liu Y
Journal of experimental & clinical cancer research : CR 2017 Jan 10;36(1):10
Journal of experimental & clinical cancer research : CR 2017 Jan 10;36(1):10
Thymosin beta 4 silencing suppresses proliferation and invasion of non-small cell lung cancer cells by repressing Notch1 activation.
Huang D, Wang S, Wang A, Chen X, Zhang H
Acta biochimica et biophysica Sinica 2016 Sep;48(9):788-94
Acta biochimica et biophysica Sinica 2016 Sep;48(9):788-94
Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth.
Nemeth Z, Csizmadia E, Vikstrom L, Li M, Bisht K, Feizi A, Otterbein S, Zuckerbraun B, Costa DB, Pandolfi PP, Fillinger J, Döme B, Otterbein LE, Wegiel B
Oncotarget 2016 Apr 26;7(17):23919-32
Oncotarget 2016 Apr 26;7(17):23919-32
TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production.
Wang J, Lu R, Yang J, Li H, He Z, Jing N, Wang X, Wang Y
Nature communications 2015 Nov 19;6:8876
Nature communications 2015 Nov 19;6:8876
Neuropathological and biochemical assessments of an Alzheimer's disease patient treated with the γ-secretase inhibitor semagacestat.
Roher AE, Maarouf CL, Kokjohn TA, Whiteside CM, Kalback WM, Serrano G, Belden C, Liebsack C, Jacobson SA, Sabbagh MN, Beach TG
American journal of neurodegenerative disease 2014;3(3):115-33
American journal of neurodegenerative disease 2014;3(3):115-33
Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/β-catenin pathway.
Sun Q, Wang R, Luo J, Wang P, Xiong S, Liu M, Cheng B
International journal of oncology 2014 Oct;45(4):1638-48
International journal of oncology 2014 Oct;45(4):1638-48
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Notch1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of mouse Notch1. This antibody recognizes human antigen. The Notch1 antibody has been validated for the following applications: ELISA, WB analysis.
