22788-1-AP

antibody from Proteintech Group

Targeting: HIC2 HRG22, KIAA1020, ZBTB30, ZNF907

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

22788-1-AP

Provider

Proteintech Group

Product name

HIC2 antibody

Antibody type

Polyclonal

Description

HIC2 antibody (Cat. #22788-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Direct and indirect regulation of fetal globin transcript by RNA-binding protein IGF2BP1.

Coyne S, Wu T, Hossain M, Vinjamur D, Starrs M, Zeng J, Andresen F, Gutierrez A, Shimamura A, Bauer DE
bioRxiv : the preprint server for biology 2025 Sep 9;

---

HIC2 suppresses glioblastoma progression via transcriptional repression of SEMA3A and inhibition of TGF-β signaling.

Zhang L, Yang J, Ke X, Huang N, Zhou D, Cai H
Free radical biology & medicine 2025 Dec 1;240:674-684

---

let-7 miRNAs repress HIC2 to regulate BCL11A transcription and hemoglobin switching.

Huang P, Peslak SA, Shehu V, Keller CA, Giardine B, Shi J, Hardison RC, Blobel GA, Khandros E
Blood 2024 May 9;143(19):1980-1991

---

Small extracellular vesicle-associated miR-6068 promotes aggressive phenotypes of prostate cancer through miR-6068/HIC2/SIRT1 axis.

Gaballah MSA, Ali HEA, Hassan ZA, Mahgoub S, Ali HI, Rhim JS, Zerfaoui M, El Sayed KA, Stephen D, Sylvester PW, Abd Elmageed ZY
American journal of cancer research 2022;12(8):4015-4027

---

HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription.

Huang P, Peslak SA, Ren R, Khandros E, Qin K, Keller CA, Giardine B, Bell HW, Lan X, Sharma M, Horton JR, Abdulmalik O, Chou ST, Shi J, Crossley M, Hardison RC, Cheng X, Blobel GA
Nature genetics 2022 Sep;54(9):1417-1426