Antibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- NBP2-24905 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal TLR7 Antibody
- Antibody type
- Polyclonal
Submitted references The genetic background influences the cellular and humoral immune responses to vaccines.
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
Analysis of the membrane proteome of ciprofloxacin-resistant macrophages by stable isotope labeling with amino acids in cell culture (SILAC).
Identification of lineage relationships and novel markers of blood and skin human dendritic cells.
Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses.
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Toll-like receptor 7-triggered immune response in the lung mediates acute and long-lasting suppression of experimental asthma.
Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block.
Toll-like receptor 7 mediates pruritus.
Toll-like receptors 3, 4, and 7 are expressed in the enteric nervous system and dorsal root ganglia.
Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells.
Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling.
Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling.
Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract.
Antitumor effects of imidazoquinolines in urothelial cell carcinoma of the bladder.
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice.
Toll-like receptor-7 modulates immune complex glomerulonephritis.
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad.
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad.
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.
Zeng M, Nourishirazi E, Guinet E, Nouri-Shirazi M
Clinical and experimental immunology 2016 Nov;186(2):190-204
Clinical and experimental immunology 2016 Nov;186(2):190-204
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
Abdi J, Mutis T, Garssen J, Redegeld F
PloS one 2013;8(4):e60671
PloS one 2013;8(4):e60671
Analysis of the membrane proteome of ciprofloxacin-resistant macrophages by stable isotope labeling with amino acids in cell culture (SILAC).
Caceres NE, Aerts M, Marquez B, Mingeot-Leclercq MP, Tulkens PM, Devreese B, Van Bambeke F
PloS one 2013;8(3):e58285
PloS one 2013;8(3):e58285
Identification of lineage relationships and novel markers of blood and skin human dendritic cells.
Harman AN, Bye CR, Nasr N, Sandgren KJ, Kim M, Mercier SK, Botting RA, Lewin SR, Cunningham AL, Cameron PU
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):66-79
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):66-79
Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses.
Krejbich-Trotot P, Denizot M, Hoarau JJ, Jaffar-Bandjee MC, Das T, Gasque P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Jan;25(1):314-25
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 Jan;25(1):314-25
Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific.
Wu J, Meng Z, Jiang M, Zhang E, Trippler M, Broering R, Bucchi A, Krux F, Dittmer U, Yang D, Roggendorf M, Gerken G, Lu M, Schlaak JF
Immunology 2010 Mar;129(3):363-74
Immunology 2010 Mar;129(3):363-74
Toll-like receptor 7-triggered immune response in the lung mediates acute and long-lasting suppression of experimental asthma.
Xirakia C, Koltsida O, Stavropoulos A, Thanassopoulou A, Aidinis V, Sideras P, Andreakos E
American journal of respiratory and critical care medicine 2010 Jun 1;181(11):1207-16
American journal of respiratory and critical care medicine 2010 Jun 1;181(11):1207-16
Ro60-associated single-stranded RNA links inflammation with fetal cardiac fibrosis via ligation of TLRs: a novel pathway to autoimmune-associated heart block.
Clancy RM, Alvarez D, Komissarova E, Barrat FJ, Swartz J, Buyon JP
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 15;184(4):2148-55
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 15;184(4):2148-55
Toll-like receptor 7 mediates pruritus.
Liu T, Xu ZZ, Park CK, Berta T, Ji RR
Nature neuroscience 2010 Dec;13(12):1460-2
Nature neuroscience 2010 Dec;13(12):1460-2
Toll-like receptors 3, 4, and 7 are expressed in the enteric nervous system and dorsal root ganglia.
Barajon I, Serrao G, Arnaboldi F, Opizzi E, Ripamonti G, Balsari A, Rumio C
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Nov;57(11):1013-23
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009 Nov;57(11):1013-23
Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells.
Clark RA, Huang SJ, Murphy GF, Mollet IG, Hijnen D, Muthukuru M, Schanbacher CF, Edwards V, Miller DM, Kim JE, Lambert J, Kupper TS
The Journal of experimental medicine 2008 Sep 29;205(10):2221-34
The Journal of experimental medicine 2008 Sep 29;205(10):2221-34
Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling.
Kalali BN, Köllisch G, Mages J, Müller T, Bauer S, Wagner H, Ring J, Lang R, Mempel M, Ollert M
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2694-704
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2694-704
Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling.
Kalali BN, Köllisch G, Mages J, Müller T, Bauer S, Wagner H, Ring J, Lang R, Mempel M, Ollert M
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2694-704
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 15;181(4):2694-704
Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract.
Palladino MA, Johnson TA, Gupta R, Chapman JL, Ojha P
Biology of reproduction 2007 Jun;76(6):958-64
Biology of reproduction 2007 Jun;76(6):958-64
Antitumor effects of imidazoquinolines in urothelial cell carcinoma of the bladder.
Smith EB, Schwartz M, Kawamoto H, You X, Hwang D, Liu H, Scherr DS
The Journal of urology 2007 Jun;177(6):2347-51
The Journal of urology 2007 Jun;177(6):2347-51
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.
Brinkmann MM, Spooner E, Hoebe K, Beutler B, Ploegh HL, Kim YM
The Journal of cell biology 2007 Apr 23;177(2):265-75
The Journal of cell biology 2007 Apr 23;177(2):265-75
Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice.
Patole PS, Pawar RD, Lech M, Zecher D, Schmidt H, Segerer S, Ellwart A, Henger A, Kretzler M, Anders HJ
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006 Nov;21(11):3062-73
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006 Nov;21(11):3062-73
Toll-like receptor-7 modulates immune complex glomerulonephritis.
Pawar RD, Patole PS, Zecher D, Segerer S, Kretzler M, Schlöndorff D, Anders HJ
Journal of the American Society of Nephrology : JASN 2006 Jan;17(1):141-9
Journal of the American Society of Nephrology : JASN 2006 Jan;17(1):141-9
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad.
François S, El Benna J, Dang PM, Pedruzzi E, Gougerot-Pocidalo MA, Elbim C
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3633-42
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3633-42
Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad.
François S, El Benna J, Dang PM, Pedruzzi E, Gougerot-Pocidalo MA, Elbim C
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3633-42
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3633-42
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Srivastava MD, Srivastava BI
Leukemia research 2005 Jul;29(7):813-20
Leukemia research 2005 Jul;29(7):813-20
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.
Hart OM, Athie-Morales V, O'Connor GM, Gardiner CM
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 1;175(3):1636-42
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 1;175(3):1636-42
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.
Hart OM, Athie-Morales V, O'Connor GM, Gardiner CM
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 1;175(3):1636-42
Journal of immunology (Baltimore, Md. : 1950) 2005 Aug 1;175(3):1636-42
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TLR7 Antibody [Azide Free] [NBP2-24905] - analysis of TLR7 in RAW cell lysate using this antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TLR7 Antibody [Azide Free] [NBP2-24905] - Analysis of human colon tissue using NBP2-24905 (top) and an isotype control (bottom) at 5 ug/ml.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR7 Antibody [Azide Free] [NBP2-24905] - Intracellular staining by analysis of TLR7 in human PBMC using this antibody at 0.5 ug/ml. Shaded histogram is cells alone, green is rabbit IgG isotype control (NBP2-24891), red represents anti-TLR7 antibody. NBP2-30343PE was used for secondary.