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- Antigen structure
- References [2]
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- Validations
- Flow cytometry [2]
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- Product number
- NBP2-27251 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal TLR7 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation.
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Chauhan SK, Singh VV, Rai R, Rai M, Rai G
Journal of clinical immunology 2013 Jul;33(5):954-64
Journal of clinical immunology 2013 Jul;33(5):954-64
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann SM, Krüger C, Park B, Derkow K, Rosenberger K, Baumgart J, Trimbuch T, Eom G, Hinz M, Kaul D, Habbel P, Kälin R, Franzoni E, Rybak A, Nguyen D, Veh R, Ninnemann O, Peters O, Nitsch R, Heppner FL, Golenbock D, Schott E, Ploegh HL, Wulczyn FG, Lehnardt S
Nature neuroscience 2012 Jun;15(6):827-35
Nature neuroscience 2012 Jun;15(6):827-35
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR7 Antibody (4G6) [PE] [NBP2-27251] - Intracellular analysis of TLR7 in 10^6 human BDCM cells (red) and 0.5 ug of mouse IgG1 isotype control (green). this antibody was used for this test.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: TLR7 Antibody (4G6) [PE] [NBP2-27251] - An intracellular stain was performed on THP-1 cells with TLR7 (4G6) antibody NBP2-27251 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Phycoerythrin.
