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Blocking/NeutralizingAntibody data
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- References [2]
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- Blocking/Neutralizing [1]
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- Product number
- AB-219-NA - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IL-12 Antibody
- Antibody type
- Polyclonal
Submitted references A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association.
IL-33 induces IL-9 production in human CD4+ T cells and basophils.
Huang H, Liu S, Jean M, Simpson S, Huang H, Merkley M, Hayashi T, Kong W, RodrÃguez-Sánchez I, Zhang X, Yosief HO, Miao H, Que J, Kobie JJ, Bradner J, Santoso NG, Zhang W, Zhu J
Frontiers in microbiology 2017;8:1035
Frontiers in microbiology 2017;8:1035
IL-33 induces IL-9 production in human CD4+ T cells and basophils.
Blom L, Poulsen BC, Jensen BM, Hansen A, Poulsen LK
PloS one 2011;6(7):e21695
PloS one 2011;6(7):e21695
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Supportive validation
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- Novus Biologicals (provider)
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- Cell Proliferation Induced by IL-12 and Neutralization by Human IL-12 Antibody. Recombinant Human IL-12 (Catalog # 219-IL) stimulates proliferation in PHA-activated human peripheral blood mononuclear cells (PBMC) in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human IL-12 (1 ng/mL) is neutralized (green line) by increasing concentrations of Human IL-12 Polyclonal Antibody (Catalog # AB-219-NA). The ND50 is typically 1-2 µg/mL.
