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- References [17]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 13224-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13224-1-AP, RRID:AB_2138714
- Product name
- LRG1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LRG1 antibody (Cat. #13224-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Leucine-Rich α-2-Glycoprotein 1 Suppresses Endothelial Cell Activation Through ADAM10-Mediated Shedding of TNF-α Receptor.
Prognostic Value of LRG1 in Breast Cancer: A Retrospective Study.
LRG1 facilitates corneal fibrotic response by inducing neutrophil chemotaxis via Stat3 signaling in alkali-burned mouse corneas.
LRG1 Promotes Metastatic Dissemination of Melanoma through Regulating EGFR/STAT3 Signalling.
Single-Cell Transcriptomes Reveal a Complex Cellular Landscape in the Middle Ear and Differential Capacities for Acute Response to Infection.
A Multifunctional Role of Leucine-Rich α-2-Glycoprotein 1 in Cutaneous Wound Healing Under Normal and Diabetic Conditions.
MicroRNA-497 elevation or LRG1 knockdown promotes osteoblast proliferation and collagen synthesis in osteoporosis via TGF-β1/Smads signalling pathway.
Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach.
Leucine-rich α2-glycoprotein-1 upregulation in plasma and kidney of patients with lupus nephritis.
Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao.
Molecular Beacon Gold Nanosensors for Leucine-Rich Alpha-2-Glycoprotein-1 Detection in Pathological Angiogenesis.
Gene expression profiles of glomerular endothelial cells support their role in the glomerulopathy of diabetic mice.
LRG1 suppresses the migration and invasion of hepatocellular carcinoma cells.
Leucine-rich α-2-glycoprotein promotes TGFβ1-mediated growth suppression in the Lewis lung carcinoma cell lines.
Clinicopathological Significance of Leucine-Rich α2-Glycoprotein-1 in Sera of Patients With Pancreatic Cancer.
Serum leucine-rich alpha-2 glycoprotein is a disease activity biomarker in ulcerative colitis.
A combination of serum leucine-rich α-2-glycoprotein 1, CA19-9 and interleukin-6 differentiate biliary tract cancer from benign biliary strictures.
Pang KT, Ghim M, Liu C, Tay HM, Fhu CW, Chia RN, Qiu B, Sarathchandra P, Chester AH, Yacoub MH, Wilkinson FL, Weston R, Warboys CM, Hou HW, Weinberg PD, Wang X
Frontiers in cell and developmental biology 2021;9:706143
Frontiers in cell and developmental biology 2021;9:706143
Prognostic Value of LRG1 in Breast Cancer: A Retrospective Study.
Zhang YS, Han L, Yang C, Liu YJ, Zhang XM
Oncology research and treatment 2021;44(1-2):36-42
Oncology research and treatment 2021;44(1-2):36-42
LRG1 facilitates corneal fibrotic response by inducing neutrophil chemotaxis via Stat3 signaling in alkali-burned mouse corneas.
Yu B, Yang L, Song S, Li W, Wang H, Cheng J
American journal of physiology. Cell physiology 2021 Sep 1;321(3):C415-C428
American journal of physiology. Cell physiology 2021 Sep 1;321(3):C415-C428
LRG1 Promotes Metastatic Dissemination of Melanoma through Regulating EGFR/STAT3 Signalling.
Kwan YP, Teo MHY, Lim JCW, Tan MS, Rosellinny G, Wahli W, Wang X
Cancers 2021 Jun 30;13(13)
Cancers 2021 Jun 30;13(13)
Single-Cell Transcriptomes Reveal a Complex Cellular Landscape in the Middle Ear and Differential Capacities for Acute Response to Infection.
Ryan AF, Nasamran CA, Pak K, Draf C, Fisch KM, Webster N, Kurabi A
Frontiers in genetics 2020;11:358
Frontiers in genetics 2020;11:358
A Multifunctional Role of Leucine-Rich α-2-Glycoprotein 1 in Cutaneous Wound Healing Under Normal and Diabetic Conditions.
Liu C, Teo MHY, Pek SLT, Wu X, Leong ML, Tay HM, Hou HW, Ruedl C, Moss SE, Greenwood J, Tavintharan S, Hong W, Wang X
Diabetes 2020 Nov;69(11):2467-2480
Diabetes 2020 Nov;69(11):2467-2480
MicroRNA-497 elevation or LRG1 knockdown promotes osteoblast proliferation and collagen synthesis in osteoporosis via TGF-β1/Smads signalling pathway.
Gu Z, Xie D, Huang C, Ding R, Zhang R, Li Q, Lin C, Qiu Y
Journal of cellular and molecular medicine 2020 Nov;24(21):12619-12632
Journal of cellular and molecular medicine 2020 Nov;24(21):12619-12632
Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach.
Lipski DA, Foucart V, Dewispelaere R, Caspers LE, Defrance M, Bruyns C, Willermain F
BMC ophthalmology 2020 Mar 17;20(1):106
BMC ophthalmology 2020 Mar 17;20(1):106
Leucine-rich α2-glycoprotein-1 upregulation in plasma and kidney of patients with lupus nephritis.
Yang Y, Luo R, Cheng Y, Liu T, Dai W, Li Y, Ge S, Xu G
BMC nephrology 2020 Apr 6;21(1):122
BMC nephrology 2020 Apr 6;21(1):122
Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao.
Xing QQ, Liu LW, Zhao X, Lu Y, Dong YM, Liang ZQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109390
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109390
Molecular Beacon Gold Nanosensors for Leucine-Rich Alpha-2-Glycoprotein-1 Detection in Pathological Angiogenesis.
Lio DCS, Liu C, Wiraja C, Qiu B, Fhu CW, Wang X, Xu C
ACS sensors 2018 Sep 28;3(9):1647-1655
ACS sensors 2018 Sep 28;3(9):1647-1655
Gene expression profiles of glomerular endothelial cells support their role in the glomerulopathy of diabetic mice.
Fu J, Wei C, Zhang W, Schlondorff D, Wu J, Cai M, He W, Baron MH, Chuang PY, Liu Z, He JC, Lee K
Kidney international 2018 Aug;94(2):326-345
Kidney international 2018 Aug;94(2):326-345
LRG1 suppresses the migration and invasion of hepatocellular carcinoma cells.
Zhang Y, Luo Q, Wang N, Hu F, Jin H, Ge T, Wang C, Qin W
Medical oncology (Northwood, London, England) 2015 May;32(5):146
Medical oncology (Northwood, London, England) 2015 May;32(5):146
Leucine-rich α-2-glycoprotein promotes TGFβ1-mediated growth suppression in the Lewis lung carcinoma cell lines.
Takemoto N, Serada S, Fujimoto M, Honda H, Ohkawara T, Takahashi T, Nomura S, Inohara H, Naka T
Oncotarget 2015 May 10;6(13):11009-22
Oncotarget 2015 May 10;6(13):11009-22
Clinicopathological Significance of Leucine-Rich α2-Glycoprotein-1 in Sera of Patients With Pancreatic Cancer.
Furukawa K, Kawamoto K, Eguchi H, Tanemura M, Tanida T, Tomimaru Y, Akita H, Hama N, Wada H, Kobayashi S, Nonaka Y, Takamatsu S, Shinzaki S, Kumada T, Satomura S, Ito T, Serada S, Naka T, Mori M, Doki Y, Miyoshi E, Nagano H
Pancreas 2015 Jan;44(1):93-8
Pancreas 2015 Jan;44(1):93-8
Serum leucine-rich alpha-2 glycoprotein is a disease activity biomarker in ulcerative colitis.
Serada S, Fujimoto M, Terabe F, Iijima H, Shinzaki S, Matsuzaki S, Ohkawara T, Nezu R, Nakajima S, Kobayashi T, Plevy SE, Takehara T, Naka T
Inflammatory bowel diseases 2012 Nov;18(11):2169-79
Inflammatory bowel diseases 2012 Nov;18(11):2169-79
A combination of serum leucine-rich α-2-glycoprotein 1, CA19-9 and interleukin-6 differentiate biliary tract cancer from benign biliary strictures.
Sandanayake NS, Sinclair J, Andreola F, Chapman MH, Xue A, Webster GJ, Clarkson A, Gill A, Norton ID, Smith RC, Timms JF, Pereira SP
British journal of cancer 2011 Oct 25;105(9):1370-8
British journal of cancer 2011 Oct 25;105(9):1370-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 13224-1-AP(LRG1 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LRG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LRG1. This antibody recognizes human, mouse antigen. The LRG1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
